Hub : Genes

Ppp1r3c

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018494 0.04 0.03 2.1e-03 -0 -0 -0 -0 7.1e-01 5.1e-01 5.6e-01 8.0e-01
2 BLA gene expression ENSRNOG00000018494 0.48 0.14 0.0e+00 0.27 0.33 0.32 0.31 9.5e-15 2.3e-18 1.7e-17 4.4e-17
3 Brain gene expression ENSRNOG00000018494 0.43 0.11 0.0e+00 0.33 0.32 0.37 0.36 2.7e-31 1.4e-30 6.1e-36 3.4e-34
4 Eye gene expression ENSRNOG00000018494 0.32 0.17 4.2e-03 -0.01 0.06 0.06 0 5.6e-01 4.1e-02 4.7e-02 2.7e-01
5 IL gene expression ENSRNOG00000018494 0.22 0.12 6.0e-04 0.1 0.11 0.12 0.1 2.4e-03 1.3e-03 1.0e-03 2.2e-03
6 LHb gene expression ENSRNOG00000018494 0.47 0.16 2.3e-09 0.25 0.36 0.39 0.33 9.4e-07 1.7e-09 2.2e-10 1.1e-08
7 Liver alternative polyA ENSRNOT00000024941 0.06 0.04 3.8e-07 0.07 0.05 0.05 0.06 5.5e-08 1.3e-06 1.3e-06 2.3e-07
8 Liver alternative polyA ENSRNOT00000107925 0.08 0.05 2.2e-08 0.08 0.06 0.07 0.07 4.2e-09 9.5e-08 3.5e-08 1.7e-08
9 Liver gene expression ENSRNOG00000018494 0.03 0.02 3.4e-03 0.02 0 0.01 0.01 2.7e-03 8.6e-02 3.7e-02 4.2e-02
10 Liver isoform ratio ENSRNOT00000024941 0.03 0.02 1.3e-03 0.02 0.02 0.03 0.02 1.4e-03 1.6e-03 8.3e-04 1.9e-03
11 Liver isoform ratio ENSRNOT00000107925 0.03 0.02 2.1e-03 0.02 0.02 0.02 0.02 2.4e-03 1.6e-03 1.1e-03 2.3e-03
12 NAcc gene expression ENSRNOG00000018494 0.41 0.11 0.0e+00 0.26 0.33 0.38 0.38 1.3e-19 2.2e-25 2.0e-29 1.2e-29
13 OFC gene expression ENSRNOG00000018494 0.35 0.13 4.2e-07 0.2 0.2 0.28 0.29 2.0e-05 1.6e-05 2.1e-07 1.2e-07
14 PL gene expression ENSRNOG00000018494 0.49 0.14 0.0e+00 0.24 0.24 0.36 0.32 4.2e-18 2.4e-18 9.7e-29 3.5e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.10.52.10.5-0.6-0.4-0.5-0.4-0.60.8-0.80.50.7-1.5-0.6-0.7-0.5
BMI without tail0.10.32.80.3-0.2-0.3-0.4-0.3-0.40.3-0.30.50.3-1.7-0.4-0.5-0.1
Body weight0.62.412.00.40.60.2-0.7-0.2-1.11.9-1.93.01.9-3.5-0.3-0.30.4
Epididymis fat weight0.20.51.8-0.50.90.70.50.70.30.4-0.41.20.4-1.40.40.50.3
Glucose0.10.10.3-0.30.50.40.00.5-0.1-0.00.0-0.1-0.00.30.50.40.4
Heart weight0.20.21.1-0.20.2-0.3-0.5-0.3-0.2-0.60.6-0.7-0.5-1.00.4-0.1-0.4
Left kidney weight0.41.23.1-1.11.81.30.61.00.10.3-0.31.70.3-1.21.11.21.7
Right kidney weight0.82.26.3-2.02.51.81.21.60.8-0.60.60.9-0.7-0.42.01.91.7
Tail length0.31.04.8-0.41.31.00.30.6-0.00.6-0.62.20.6-1.30.50.61.6
Length with tail0.62.111.2-0.21.50.9-0.10.3-0.61.4-1.43.41.5-2.40.30.61.6
Length without tail0.71.48.2-0.11.11.00.20.4-0.41.4-1.42.91.4-0.80.20.61.5
Liver weight, left0.91.47.00.40.50.5-0.40.1-1.01.8-1.82.61.8-1.3-0.30.00.5
Liver weight, right0.61.13.5-0.91.41.30.91.20.40.8-0.81.90.8-0.50.90.90.9
Parametrial fat weight0.40.72.3-0.61.11.10.50.70.20.5-0.51.50.5-1.00.60.61.2
Retroperitoneal fat weight0.10.31.60.20.30.1-0.2-0.0-0.30.4-0.41.10.4-1.3-0.30.00.2
Intraocular pressure0.71.04.10.8-0.6-0.8-1.0-0.9-0.90.9-0.90.50.9-2.0-0.9-0.9-0.8
Extensor digitorum longus weight0.52.08.5-0.61.42.01.01.70.50.9-0.92.90.9-0.01.00.92.1
Soleus weight1.13.25.02.0-1.8-1.7-2.1-1.9-2.21.6-1.60.41.6-1.7-1.9-1.9-1.8
Tibialis anterior weight0.51.99.3-0.31.11.81.01.60.51.4-1.43.11.4-0.10.60.61.6
Tibia length0.00.00.10.10.2-0.1-0.4-0.3-0.30.1-0.10.30.1-0.3-0.00.00.1
Number of licking bursts1.92.23.8-1.91.51.21.81.42.0-1.61.6-0.6-1.61.11.71.41.0
Food consumed during 24 hour testing period0.20.30.7-0.70.80.50.30.50.3-0.50.50.0-0.5-0.10.80.70.5
Times rat made contact with spout0.20.21.1-0.20.30.60.60.40.60.2-0.21.00.2-0.3-0.00.20.4
Mean time between licks in bursts0.60.92.7-0.70.30.10.30.40.6-1.41.4-1.6-1.41.00.90.50.6
Mean num. licks in bursts1.41.62.61.6-1.2-0.7-1.3-1.0-1.51.6-1.61.11.6-1.1-1.5-1.1-0.6
Std. dev. time between licks in bursts1.51.83.6-1.40.80.51.00.91.2-1.91.9-1.7-1.91.11.51.00.7
Water consumed over 24 hours1.11.32.3-1.11.21.51.51.51.3-0.40.41.2-0.40.81.11.11.4
Indifference point 0 sec0.20.32.5-0.70.6-0.10.1-0.10.1-0.30.3-0.2-0.3-1.60.60.3-0.2
Indifference point AUC1.61.92.7-1.61.51.41.41.41.5-1.41.4-0.6-1.41.11.51.71.1
Indifference point function ln k1.42.02.91.5-1.1-1.0-1.4-1.2-1.51.7-1.71.71.7-1.6-1.4-1.4-0.4
Indifference point function log k1.42.02.91.5-1.1-1.0-1.4-1.2-1.51.7-1.71.71.7-1.6-1.4-1.4-0.4
Delay discounting total patch changes 0 sec0.20.32.6-0.60.6-0.1-0.0-0.10.0-0.20.2-0.1-0.2-1.60.50.3-0.1
Delay discounting total patch changes 12 sec1.11.42.7-1.40.90.61.10.91.3-1.61.6-1.6-1.60.61.21.1-0.2
Delay discounting total patch changes 18 sec0.30.40.7-0.90.80.40.70.50.8-0.70.7-0.1-0.7-0.70.60.60.3
Delay discounting total patch changes 24 sec0.81.02.2-1.31.51.01.01.01.0-0.70.70.3-0.7-0.81.31.20.6
Delay discounting total patch changes 6 sec0.91.42.4-1.51.30.60.90.81.1-1.51.5-1.5-1.50.31.51.30.2
Delay discounting time to switch 0 sec0.40.61.9-0.60.10.10.60.40.8-1.11.1-1.2-1.01.40.50.30.2
Delay discounting water rate 0 sec0.20.31.00.30.00.2-0.2-0.1-0.30.7-0.70.80.7-1.0-0.2-0.0-0.2
Delay discounting water rate 12 sec0.20.41.00.3-0.0-0.3-0.6-0.4-0.70.9-0.90.60.8-1.0-0.2-0.40.0
Delay discounting water rate 18 sec0.40.61.50.4-0.0-0.1-0.6-0.2-0.81.2-1.21.01.2-1.1-0.2-0.5-0.2
Delay discounting water rate 24 sec0.60.83.30.30.40.4-0.20.2-0.51.4-1.41.81.4-1.1-0.20.10.2
Delay discounting water rate 6 sec0.20.41.30.6-0.5-0.6-0.7-0.6-0.60.4-0.40.20.4-1.1-0.5-0.6-0.7
Locomotor activity0.10.20.3-0.40.2-0.00.30.10.6-0.60.6-0.4-0.6-0.10.30.20.5
Locomotor testing distance0.20.41.4-0.60.2-0.10.40.20.7-0.90.9-1.2-0.90.40.50.40.2
Locomotor testing rearing0.10.10.3-0.00.20.30.20.20.10.5-0.50.60.4-0.1-0.00.1-0.2
Light reinforcement 11.12.06.11.3-1.4-1.6-1.3-1.4-1.11.0-1.00.01.0-2.5-1.5-1.6-1.8
Light reinforcement 20.70.95.3-0.1-0.8-1.00.2-0.40.7-1.21.2-2.3-1.20.3-0.1-0.5-0.9
Reaction time number correct1.31.93.61.4-1.2-0.9-1.1-1.1-1.21.7-1.71.11.7-1.2-1.5-1.4-1.9
Reaction time mean minus median0.50.71.80.7-0.8-1.0-1.2-1.0-1.10.1-0.1-1.00.1-0.5-0.6-0.6-1.4
Reaction time mean minus median AUC0.50.72.20.6-0.9-1.0-0.9-0.9-0.7-0.20.2-1.3-0.1-0.5-0.6-0.6-1.5
Reaction time num false alarms0.40.63.0-0.20.70.90.40.70.10.9-0.91.70.8-0.40.30.60.3
Reaction time num false alarms AUC0.40.51.6-0.61.01.00.60.90.30.4-0.41.30.40.00.70.90.6
Reaction time trials correct on left1.31.93.61.4-1.2-0.9-1.1-1.1-1.21.7-1.71.11.7-1.2-1.5-1.4-1.9
Reaction time trials on left1.31.83.41.4-1.1-0.9-1.1-1.1-1.21.6-1.61.11.6-1.2-1.4-1.3-1.8
Reaction time mean1.41.94.4-1.10.60.30.70.50.9-2.02.0-2.1-2.01.91.21.00.8
Reaction time mean AUC1.72.25.6-1.20.60.30.70.61.0-2.22.2-2.4-2.22.01.31.00.8
Median of all reaction times1.92.65.6-1.30.70.41.00.81.3-2.42.4-2.3-2.32.21.41.11.2
Reaction time omissions0.10.20.7-0.20.30.10.1-0.00.1-0.70.7-0.1-0.70.50.00.60.8
Reaction time false alarm rate0.50.71.4-0.81.21.20.81.10.6-0.10.10.9-0.10.21.01.11.2
Reaction time premature initiation rate0.40.51.30.4-0.0-0.1-0.5-0.2-0.81.1-1.11.11.1-0.5-0.4-0.4-0.3
Reaction time premature initiations1.62.34.61.3-0.7-0.7-1.3-0.9-1.62.1-2.11.82.1-1.4-1.3-1.2-1.4
Std. dev. reaction times0.30.52.4-0.1-0.2-0.6-0.5-0.5-0.3-1.01.0-1.5-1.00.30.10.2-0.4
Reaction time trials completed1.31.83.41.4-1.1-0.9-1.1-1.1-1.21.6-1.61.11.6-1.2-1.4-1.3-1.8
Reaction time trials AUC0.81.22.21.1-0.9-0.6-0.8-0.8-0.81.4-1.41.01.4-0.8-1.1-1.1-1.5
Social response proportion1.31.43.11.4-1.8-1.5-1.1-1.3-0.90.6-0.6-0.70.6-0.4-1.4-1.6-1.7
Social responses2.12.75.81.6-1.7-1.9-1.8-1.7-1.71.1-1.1-0.51.1-1.9-1.6-1.8-2.4
Social time0.60.71.4-1.10.70.40.80.50.9-1.01.0-1.2-1.00.60.90.80.6
Conditioned locomotion0.40.51.60.6-0.4-0.3-0.5-0.3-0.61.0-1.01.21.0-0.6-0.6-0.6-0.2
Cocaine response after cond. corrected0.20.20.60.5-0.5-0.6-0.4-0.8-0.30.0-0.0-0.20.0-0.3-0.8-0.3-0.5
Cocaine response after cond. not corrected0.00.00.30.10.20.20.1-0.10.00.1-0.10.50.1-0.1-0.20.20.2
Cocaine response before conditioning1.11.32.4-1.31.61.51.21.41.0-0.50.50.6-0.50.81.51.31.5
Saline control response0.30.41.0-0.30.40.70.90.70.8-0.00.00.70.01.00.20.60.8
Condit. Reinf. active minus inactive responses0.60.73.1-0.30.91.30.70.90.50.4-0.41.80.4-0.20.20.91.3
Condit. Reinf. active-inactive response ratio0.30.31.1-0.20.50.80.60.60.5-0.10.11.0-0.1-0.20.10.60.8
Condit. Reinf. active responses0.60.84.40.60.20.5-0.3-0.1-0.61.2-1.22.11.2-1.0-0.70.10.6
Condit. Reinf. inactive responses0.50.61.20.8-0.2-0.3-0.9-0.7-1.01.0-1.01.11.0-0.8-0.8-0.3-0.0
Condit. Reinf. lever presses0.10.10.20.4-0.2-0.1-0.3-0.3-0.20.2-0.20.50.2-0.2-0.5-0.10.2
Condit. Reinf. lever reinforcers received0.30.52.80.40.20.5-0.10.1-0.30.9-0.91.70.9-0.7-0.50.20.5
Pavlov. Cond. lever latency0.10.20.4-0.20.30.60.40.60.20.5-0.50.60.50.10.40.10.3
Pavlov. Cond. magazine entry latency1.21.41.6-1.21.21.11.21.11.2-1.21.2-0.2-1.21.31.21.31.2
Pavlov. Cond. change in total contacts0.40.50.8-0.60.80.80.80.70.8-0.60.60.5-0.60.70.50.90.8
Pavlov. Cond. index score0.20.30.5-0.50.60.50.50.40.5-0.60.60.3-0.60.40.30.70.6
Pavlov. Cond. latency score0.10.10.2-0.30.50.40.30.20.3-0.30.30.5-0.30.10.10.50.4
Pavlov. Cond. lever contacts0.00.10.20.0-0.0-0.2-0.1-0.3-0.0-0.50.5-0.3-0.40.2-0.20.1-0.0
Pavlov. Cond. magazine entry number2.32.93.51.8-1.7-1.6-1.8-1.7-1.91.8-1.80.41.8-1.8-1.7-1.9-1.7
Pavlov. Cond. intertrial magazine entries0.40.63.10.30.30.5-0.00.1-0.31.1-1.11.81.1-0.8-0.3-0.00.4
Pavlov. Cond. lever-magazine prob. diff.0.40.50.8-0.70.90.70.80.70.8-0.70.70.4-0.70.60.60.90.8
Pavlov. Cond. response bias0.71.01.6-1.00.90.70.90.71.0-1.31.3-0.5-1.21.10.81.10.9
Conditioned reinforcement - actives1.81.82.91.0-0.8-1.2-1.4-1.2-1.71.6-1.60.81.6-1.7-1.1-1.2-1.3
Conditioned reinforcement - inactives2.63.04.21.7-1.5-1.6-1.9-1.7-2.01.8-1.80.71.8-1.8-1.8-1.8-1.8
Conditioned locomotion2.02.43.71.5-1.6-1.7-1.8-1.6-1.91.3-1.3-0.31.3-1.8-1.4-1.7-1.9
Intermittent access intake day 1-15 change3.73.78.51.6-1.6-1.9-2.1-2.0-2.31.8-1.80.21.8-2.9-1.6-2.0-2.1
Intermittent access intake escalation3.43.49.11.4-1.4-1.8-2.0-1.9-2.21.7-1.70.11.7-3.0-1.4-1.9-2.0
Intermittent access intake escalation 21.71.74.81.0-1.1-1.3-1.4-1.2-1.51.2-1.2-0.11.2-2.2-1.0-1.5-1.6
Intermitt. access day 1 inactive lever presses0.60.71.61.1-1.2-0.9-0.8-1.3-0.50.4-0.4-0.10.4-0.5-1.2-1.0-0.6
Intermitt. access day 15 inactive lever presses4.14.57.52.4-2.4-2.5-2.5-2.7-2.31.4-1.4-0.31.4-1.7-2.5-2.2-2.6
Intermitt. access escalation Index1.00.92.9-0.80.81.21.01.30.8-0.50.5-0.0-0.51.70.90.91.3
Intermittent access day 1 total infusions0.50.61.50.6-0.2-0.2-0.5-0.3-0.71.2-1.21.21.2-0.7-0.6-0.4-0.1
Intermittent access day 15 total infusions3.33.79.51.4-1.0-1.5-2.0-1.7-2.52.3-2.31.22.3-3.1-1.4-1.7-1.4
Intermittent access terminal intake (last 3 days)2.42.66.11.2-1.1-1.4-1.6-1.4-2.01.9-1.90.61.9-2.5-1.2-1.5-1.4
Intermittent access total infusions1.41.53.10.9-0.6-0.7-1.1-0.8-1.51.7-1.71.01.8-1.8-0.9-1.0-0.8
Intermittent access day 1 locomotion0.40.41.90.20.20.2-0.2-0.1-0.30.9-0.91.41.0-0.8-0.1-0.00.6
Intermittent access day 15 total locomotion2.22.35.21.4-1.3-1.5-1.7-1.6-1.81.4-1.40.31.4-2.3-1.4-1.5-1.5
Intermittent access total locomotion0.40.41.20.4-0.3-0.3-0.4-0.4-0.60.9-0.90.61.0-1.1-0.4-0.5-0.3
Intermittent access standard deviation1.21.32.51.1-1.0-1.1-1.5-1.3-1.60.9-0.9-0.11.0-1.3-1.0-1.2-1.4
Cocaine induced anxiety0.20.31.0-0.30.30.60.70.60.7-0.20.20.2-0.21.00.40.50.7
Post-drug Anxiety0.20.20.50.4-0.6-0.4-0.1-0.30.2-0.30.3-0.6-0.30.7-0.4-0.2-0.6
Baseline Anxiety0.30.30.90.5-0.7-0.8-0.6-0.7-0.5-0.20.2-0.5-0.2-0.4-0.6-0.5-1.0
Lifetime Intake1.11.32.60.7-0.6-0.7-1.0-0.7-1.41.6-1.60.81.6-1.6-0.8-1.0-0.8
Incentive Sensitization - Responses5.25.215.51.7-1.5-1.7-2.1-1.8-2.42.6-2.61.32.6-3.9-1.8-2.3-2.0
Incentive Sensitization - Breakpoint5.35.315.71.8-1.6-1.8-2.2-1.9-2.52.6-2.61.22.6-4.0-1.9-2.4-2.0
Progressive ratio test 1 active lever presses1.41.52.11.2-1.0-1.1-1.3-1.2-1.51.5-1.50.91.5-1.0-1.3-1.1-0.8
Progressive ratio test 1 breakpoint1.51.62.11.2-1.1-1.2-1.3-1.3-1.51.5-1.50.81.5-1.2-1.3-1.2-0.9
Progressive ratio test 1 inactive lever presses2.72.95.01.4-1.4-1.4-1.5-1.5-1.82.0-2.01.02.0-2.2-1.7-1.9-1.5
Progressive ratio test 2 active lever presses4.34.610.61.8-1.4-1.7-2.1-1.9-2.52.5-2.51.42.5-3.3-1.9-2.1-1.8
Progressive ratio test 2 breakpoint5.46.012.52.1-1.7-2.0-2.4-2.1-2.82.8-2.81.62.8-3.5-2.2-2.4-2.0
Progressive ratio test 2 inactive lever presses3.94.56.62.1-2.1-2.2-2.2-2.0-2.32.1-2.10.42.1-2.3-2.2-2.3-2.6
Total sessions with >9 infusions0.40.42.60.1-0.1-0.5-0.5-0.5-0.60.7-0.70.30.8-1.6-0.3-0.5-0.5
Short access day 1 total inactive lever presses4.55.08.32.3-2.6-2.6-2.3-2.5-2.11.5-1.5-0.31.5-2.6-2.6-2.8-2.9
Short access day 10 total inactive lever presses0.20.30.9-0.1-0.4-0.30.4-0.10.6-0.60.6-1.0-0.60.7-0.2-0.2-0.3
Short access day 1 total infusions0.00.00.1-0.30.1-0.1-0.00.2-0.10.0-0.0-0.10.1-0.20.1-0.0-0.1
Short access day 10 total infusions0.10.10.4-0.40.2-0.1-0.00.1-0.20.2-0.2-0.60.2-0.20.40.0-0.2
Short access total infusions0.60.61.40.4-0.4-0.6-0.7-0.5-0.91.2-1.20.51.2-1.2-0.5-0.7-0.7
Short access day 1 locomotion0.30.30.8-0.90.80.40.60.70.4-0.20.20.3-0.2-0.70.70.50.6
Short access day 10 total locomotion0.10.10.3-0.20.10.40.40.20.5-0.00.00.10.00.20.20.20.5
Short access total locomotion0.10.10.3-0.50.30.20.40.20.5-0.10.1-0.1-0.1-0.40.40.10.3
Compulsive drug intake0.60.64.10.50.20.3-0.3-0.1-0.50.8-0.82.00.8-1.2-0.4-0.10.7
One hour access (0.3 mA shock)6.87.917.02.3-1.8-2.2-2.8-2.3-3.33.3-3.32.03.3-4.1-2.4-2.6-2.3
One hour access (shock baseline)2.02.33.81.1-1.1-1.5-1.6-1.4-1.91.7-1.70.01.8-1.9-1.1-1.6-1.7
Number of responses in last shaping day2.32.35.41.3-1.2-1.5-1.5-1.5-1.81.4-1.40.81.4-2.3-1.6-1.5-1.3
Context. condit. distance diff. score1.01.35.51.0-0.20.3-0.5-0.1-1.01.6-1.62.31.6-1.1-1.0-0.30.3
Locomotion velocity, session 11.01.14.5-0.5-0.2-0.60.3-0.30.8-1.71.7-2.1-1.70.40.50.1-0.1
Locomotion distance, session 10.00.10.3-0.1-0.2-0.30.1-0.20.3-0.30.3-0.5-0.30.10.0-0.00.1
Locomotion velocity, session 20.40.41.2-0.60.30.10.50.20.7-1.11.1-0.5-1.10.30.50.50.7
Locomotion distance, session 20.71.01.8-1.11.11.01.01.11.1-0.70.70.2-0.70.71.21.11.4
Locomotion velocity, session 30.10.10.50.00.30.40.10.2-0.00.2-0.20.70.2-0.1-0.00.30.4
Locomotion distance, session 30.60.62.3-0.30.91.20.51.00.10.4-0.41.50.40.40.40.81.1
Stereotopy head waving bouts, day 30.50.61.40.8-1.1-1.0-0.8-1.1-0.5-0.20.2-1.2-0.2-0.3-0.9-0.8-1.1
Stereotopy head waving duration, day 30.60.71.40.8-1.2-1.1-0.8-1.1-0.50.1-0.1-0.90.1-0.5-1.0-1.0-1.1
Locomotion velocity, session 70.40.41.60.00.40.80.50.60.11.0-1.01.31.00.5-0.10.30.4
Locomotion distance, session 70.40.52.30.20.20.50.20.4-0.21.1-1.11.51.10.1-0.20.00.3
Stereotopy head waving bouts, day 70.10.10.30.1-0.1-0.2-0.2-0.3-0.0-0.50.5-0.5-0.5-0.1-0.10.0-0.0
Stereotopy head waving duration, day 70.20.20.70.4-0.5-0.6-0.7-0.7-0.5-0.40.4-0.8-0.4-0.2-0.3-0.3-0.4
Locomotion velocity, session 80.10.20.40.3-0.2-0.1-0.3-0.1-0.60.7-0.70.40.7-0.4-0.3-0.3-0.2
Locomotion distance, session 80.40.63.30.10.40.90.40.70.10.8-0.81.80.8-0.30.00.41.0
Degree of sensitization distance0.00.00.2-0.20.00.10.40.20.40.2-0.20.10.20.10.1-0.1-0.2
Degree of sensitization stereotypy0.10.10.20.2-0.2-0.3-0.5-0.4-0.4-0.20.2-0.2-0.2-0.2-0.2-0.1-0.0
Condit. Reinf. active minus inactive responses1.51.72.3-1.31.31.31.41.31.5-1.31.3-0.0-1.31.31.21.51.5
Condit. Reinf. active-inactive response ratio0.80.91.8-0.80.50.30.60.50.9-1.31.3-1.3-1.31.30.90.70.5
Condit. Reinf. active responses0.70.92.4-0.71.11.21.01.10.9-0.30.31.3-0.30.60.61.11.5
Condit. Reinf. inactive responses0.60.74.80.40.20.5-0.00.1-0.21.0-1.02.21.0-0.8-0.60.10.6
Incentive salience index mean2.83.35.1-1.92.02.02.02.02.0-1.51.50.4-1.51.71.82.22.3
Condit. Reinf. lever presses2.63.64.9-1.92.02.12.22.12.2-1.61.60.2-1.61.91.82.22.2
Time in familiar zone, hab. session 10.30.30.50.5-0.7-0.7-0.6-0.7-0.60.3-0.3-0.50.3-0.1-0.6-0.6-0.6
Time in novel zone, hab. session 10.60.61.0-0.90.80.70.90.90.9-0.80.8-0.1-0.80.41.00.70.6
Total zone transitions, hab. session 10.10.20.30.5-0.6-0.5-0.4-0.5-0.30.3-0.3-0.10.3-0.1-0.6-0.5-0.5
Total locomotion distance, hab. session 10.30.51.6-0.60.40.50.90.71.1-0.70.7-0.3-0.71.30.50.60.3
Locomotion velocity, hab. session 10.70.92.0-0.90.70.91.31.11.4-0.90.9-0.1-0.91.40.70.90.7
Time in familiar zone, hab. session 20.10.10.4-0.1-0.1-0.3-0.1-0.20.1-0.40.4-0.6-0.40.00.1-0.1-0.1
Time in novel zone, hab. session 20.00.00.10.2-0.2-0.2-0.2-0.1-0.20.1-0.1-0.20.1-0.1-0.2-0.2-0.3
Total zone transitions, hab. session 20.30.30.8-0.50.40.10.30.10.5-0.90.9-0.7-0.90.50.50.50.6
Total locomotion distance, hab. session 20.50.60.9-0.80.60.50.70.70.9-0.90.9-0.6-0.90.80.80.80.8
Locomotion velocity, hab. session 20.60.81.3-1.00.80.81.00.91.1-0.90.9-0.4-0.91.01.01.00.9
Novel to familiar place preference ratio1.11.22.90.9-0.9-0.8-0.7-0.8-0.91.2-1.20.61.2-1.7-1.1-1.2-1.4
Novelty place preference1.41.53.41.1-1.1-1.0-0.9-0.9-1.11.3-1.30.61.3-1.8-1.2-1.4-1.6
Time in novel zone, NPP test1.01.02.50.8-0.8-0.8-0.7-0.7-0.91.1-1.10.41.1-1.6-0.9-1.2-1.5
Total zone transitions, NPP test1.01.51.9-1.31.31.11.31.21.4-1.21.2-0.4-1.21.41.31.41.3
Total locomotion distance, NPP test1.31.93.3-1.41.21.21.61.41.8-1.51.5-0.6-1.51.51.21.41.1
Locomotion velocity, NPP test1.42.03.6-1.41.31.31.71.51.9-1.41.4-0.4-1.41.51.21.51.4
Pavlov. Cond. lever latency1.92.44.51.5-1.7-2.0-1.9-2.0-1.70.6-0.6-0.80.6-1.4-1.5-1.8-2.1
Pavlov. Cond. magazine entry latency2.83.75.6-2.02.12.01.92.01.9-1.61.6-0.3-1.62.12.22.22.4
Pavlov. Cond. change in total contacts3.03.24.8-1.81.81.81.71.71.8-1.71.7-0.8-1.72.21.82.12.0
Pavlov. Cond. index score3.24.18.0-2.12.42.52.22.42.1-1.11.10.8-1.11.92.22.42.8
Pavlov. Cond. latency score3.44.38.7-2.12.52.62.42.52.2-0.90.91.2-0.91.82.12.52.9
Pavlov. Cond. lever contacts2.83.35.6-1.92.12.22.12.22.0-0.90.90.6-0.91.81.82.12.4
Pavlov. Cond. magazine entry number1.41.83.51.4-1.5-1.4-1.2-1.4-1.21.0-1.00.11.0-1.3-1.6-1.5-1.9
Pavlov. Cond. intertrial magazine entries0.30.31.80.5-0.10.1-0.2-0.2-0.40.7-0.71.30.7-0.7-0.5-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.3.84.78.3-2.32.52.62.42.52.3-1.31.30.5-1.32.12.42.52.9
Pavlov. Cond. response bias2.53.14.6-1.91.91.71.71.81.7-1.51.5-0.5-1.52.02.12.02.1
Bone: apparent density8.914.822.04.1-3.4-3.3-4.1-3.9-4.34.0-4.02.24.0-4.7-4.1-3.9-3.2
Bone surface4.57.911.73.1-2.5-2.5-3.2-3.1-3.32.7-2.71.32.7-3.4-3.1-2.8-2.2
Bone volume5.18.614.23.1-2.3-2.2-3.1-2.8-3.43.2-3.22.43.2-3.8-3.1-2.8-1.9
Bone: connectivity density6.610.413.63.4-3.2-3.2-3.5-3.5-3.63.1-3.10.73.1-3.7-3.5-3.4-3.0
Bone: cortical apparent density0.70.92.3-0.70.10.10.80.41.1-1.51.5-1.5-1.51.10.50.5-0.0
Bone: cortical area1.11.66.90.90.20.3-0.9-0.4-1.31.7-1.72.61.7-1.5-0.7-0.20.5
Bone: cortical porosity0.20.20.4-0.50.40.40.50.60.4-0.30.3-0.3-0.30.50.60.30.3
Bone: cortical porosity0.00.00.1-0.20.20.30.20.30.10.0-0.00.20.00.00.30.10.3
Bone: cortical thickness0.40.71.8-0.61.21.20.60.70.40.1-0.11.30.1-0.10.61.11.4
Bone: cortical thickness0.60.71.3-0.80.91.01.00.91.1-0.70.70.4-0.70.70.61.10.9
Bone: cortical tissue density0.70.92.4-0.70.00.00.80.41.0-1.51.5-1.6-1.51.10.50.4-0.1
Bone: elastic displacement0.80.95.0-0.0-0.9-0.90.1-0.30.6-1.21.2-2.2-1.20.6-0.2-0.4-0.8
Bone: elastic work0.60.82.70.6-1.4-1.3-0.4-0.80.0-0.50.5-1.7-0.5-0.3-0.7-1.0-1.0
Bone: endosteal estimation3.98.412.23.2-2.3-2.2-3.2-2.8-3.53.2-3.22.43.2-3.4-3.0-2.7-2.0
Bone: endosteal perimeter4.59.213.53.3-2.6-2.3-3.4-2.9-3.73.4-3.41.93.4-3.0-3.1-3.0-2.6
Bone: final force0.40.61.70.50.10.0-0.7-0.4-0.91.0-1.01.31.0-1.2-0.3-0.30.4
Bone: final moment0.40.71.80.7-0.3-0.4-1.0-0.8-1.10.9-0.91.00.9-1.3-0.5-0.60.0
Bone: marrow area4.39.213.23.3-2.5-2.3-3.3-2.9-3.63.3-3.32.43.3-3.5-3.1-2.9-2.2
Bone: maximum diameter6.311.616.13.7-2.6-2.2-3.6-3.0-4.04.0-4.03.34.0-3.6-3.6-3.0-2.3
Bone: maximum force1.52.65.61.6-0.9-0.9-1.8-1.5-2.01.8-1.81.81.8-2.4-1.4-1.3-0.6
Bone: maximum moment1.72.96.11.7-1.2-1.3-2.1-1.8-2.21.7-1.71.41.7-2.5-1.5-1.6-0.9
Bone: minimum diameter3.36.110.82.4-1.1-0.9-2.7-1.8-3.33.2-3.23.13.2-2.9-2.0-1.7-0.8
Bone: periosteal estimation3.77.611.22.9-1.8-1.6-2.9-2.4-3.43.2-3.23.03.2-3.3-2.7-2.3-1.4
Bone: periosteal perimeter2.94.88.22.3-1.3-1.0-2.2-1.7-2.62.9-2.92.62.9-2.3-2.1-1.7-1.2
Bone: post-yield work0.91.33.70.80.10.0-1.2-0.8-1.51.3-1.31.81.3-1.9-0.6-0.4-0.2
Bone: stiffness1.01.67.20.60.40.6-0.7-0.0-1.21.8-1.82.71.8-1.5-0.2-0.20.8
Bone: tissue strength0.30.31.60.1-0.4-0.7-0.6-0.5-0.5-0.30.3-1.3-0.3-0.20.2-0.5-0.5
Bone: trabecular number7.111.017.33.4-3.0-3.1-3.7-3.4-3.83.3-3.31.43.3-4.2-3.4-3.5-2.9
Bone: trabecular spacing4.05.28.3-2.42.32.22.52.32.6-2.12.1-0.8-2.12.92.32.52.2
Bone: trabecular thickness4.55.59.32.3-1.9-1.9-2.6-2.2-2.82.5-2.51.72.5-3.1-2.3-2.3-1.6
Bone: trabecular tissue density1.52.13.41.6-1.3-0.8-1.1-1.0-1.31.8-1.81.51.8-1.6-1.7-1.4-1.1
Breakpoint value in progressive ratio session0.40.41.70.30.10.2-0.10.1-0.31.0-1.01.31.0-0.8-0.3-0.20.1
Distance traveled before self-admin0.70.71.4-0.70.91.01.00.90.9-0.50.50.2-0.51.10.81.01.2
Distance traveled after self-admin1.92.14.11.8-2.0-1.6-1.4-1.6-1.11.0-1.0-0.30.9-0.8-1.9-1.7-1.9
Delta time in closed arm before/after self-admin2.52.43.7-1.91.91.71.51.71.4-1.31.3-0.2-1.31.11.91.81.8
Delta time in open arm before/after self-admin0.40.41.21.1-1.0-0.5-0.4-0.7-0.20.4-0.40.20.40.3-1.1-0.6-0.4
Diff in mean of infusions in LGA sessions0.20.30.9-0.30.60.80.40.70.20.2-0.21.00.30.20.30.50.6
Extinction: sum of active levers before priming0.20.21.1-0.30.60.50.30.4-0.00.0-0.00.70.10.50.30.51.0
Active lever presses in extinction session 60.90.82.00.9-0.7-0.3-0.4-0.4-0.61.4-1.41.31.4-0.7-1.0-0.7-0.4
Delta distance traveled before/after self-admin3.23.44.52.0-2.1-1.9-1.9-1.8-1.81.7-1.70.51.7-1.9-2.1-2.1-2.1
Delta ambulatory time before/after self-admin4.04.46.02.4-2.2-2.0-2.1-2.0-2.12.1-2.11.02.1-2.1-2.4-2.3-2.0
Time in closed arm before self-admin0.20.20.80.3-0.6-0.5-0.0-0.10.10.4-0.4-0.50.30.1-0.4-0.7-0.9
Time in closed arm after self-admin2.52.64.3-1.81.71.82.02.11.9-1.01.0-0.1-1.01.71.81.61.6
Time in open arm before self-admin0.10.11.4-0.30.3-0.1-0.0-0.2-0.1-0.30.30.1-0.3-1.20.30.00.2
Time in open arm after self-admin2.22.43.71.8-1.7-1.7-1.6-1.9-1.51.2-1.20.51.2-1.7-1.8-1.6-1.7
Sum of active levers in priming session hrs 5-60.60.62.20.6-1.2-1.0-0.5-0.6-0.2-0.10.1-1.5-0.10.4-0.7-0.7-1.4
Time to tail flick, vehicle, before self-admin0.30.31.40.1-0.6-0.6-0.0-0.30.2-0.30.3-1.2-0.4-0.4-0.3-0.6-0.9
Time to tail flick, vehicle, after self-admin0.80.83.4-0.50.91.00.80.80.30.8-0.81.80.80.10.50.51.4
Time to tail flick, test, before self-admin1.31.24.80.9-0.40.1-0.6-0.2-1.01.6-1.62.21.6-0.8-1.0-0.60.4
Time to tail flick, test, after self-admin0.10.10.3-0.40.30.10.50.20.5-0.20.2-0.1-0.2-0.20.20.10.2
Delta time to tail flick, vehicle, before/after SA1.61.69.6-0.00.91.20.40.7-0.21.5-1.53.11.5-0.10.30.61.6
Delta time to tail flick, test, before/after SA0.20.20.4-0.60.50.20.50.30.5-0.40.4-0.5-0.4-0.20.60.4-0.0
Ambulatory time before self-admin1.31.32.2-1.11.11.21.31.11.4-1.01.0-0.4-1.01.41.11.21.5
Ambulatory time after self-admin1.71.93.71.7-1.8-1.4-1.2-1.4-1.01.2-1.20.41.1-1.2-1.9-1.7-1.3
Total heroin consumption0.50.61.10.7-0.6-0.5-0.7-0.6-0.91.0-1.00.71.1-0.9-0.7-0.7-0.5
Area under the delay curve0.50.51.0-0.80.90.60.90.51.0-0.70.70.2-0.70.10.60.71.0
Delay disc. indifference point, 0s delay0.60.72.3-0.50.91.11.10.80.80.3-0.31.50.3-0.40.30.71.3
Delay disc. indifference point, 16s delay0.10.10.40.3-0.1-0.4-0.3-0.6-0.20.2-0.20.40.2-0.6-0.5-0.3-0.1
Delay disc. indifference point, 2s delay0.10.10.30.2-0.4-0.40.0-0.50.2-0.00.0-0.3-0.1-0.5-0.4-0.3-0.6
Delay disc. indifference point, 24s delay2.82.76.6-1.71.91.61.71.41.6-1.51.50.4-1.51.41.51.82.6
Delay disc. indifference point, 4s delay0.60.71.7-0.81.00.91.10.80.9-0.20.20.9-0.30.10.70.81.3
Delay disc. indifference point, 8s delay1.51.52.8-1.41.10.61.30.71.6-1.61.6-0.8-1.70.91.11.11.1
Delay discount exponential model param0.60.61.30.9-1.0-0.6-1.0-0.5-1.00.8-0.8-0.20.9-0.2-0.7-0.8-1.1
Delay discount hyperbolic model param0.50.50.90.8-0.8-0.5-0.9-0.4-1.00.7-0.7-0.00.8-0.2-0.6-0.7-0.9
Fecal boli incidents, locomotor time 10.10.10.3-0.20.20.40.40.50.20.3-0.30.20.30.10.20.00.6
Change in fecal boli incidents, locomotor task0.10.10.2-0.30.30.20.10.20.2-0.30.3-0.3-0.30.40.40.3-0.1
Time >=10cm from walls, locomotor time 11.21.26.10.50.60.9-0.30.2-0.71.3-1.32.51.30.4-0.10.41.6
Bouts of movement, locomotor time 10.30.41.50.1-0.1-0.3-0.3-0.3-0.50.9-0.90.50.9-1.2-0.2-0.5-0.3
Total resting periods, locomotor time 10.40.51.40.2-0.2-0.3-0.3-0.2-0.51.1-1.10.71.1-1.2-0.2-0.5-0.4
Rest time, locomotor task time 10.80.83.40.7-1.1-1.1-0.7-0.6-0.60.7-0.7-0.60.7-0.9-0.7-1.3-1.8
Distance moved, locomotor task time 12.02.26.2-1.21.81.91.31.31.2-1.01.00.8-1.01.51.21.92.5
Vertical activity count, locomotor time 10.30.31.2-0.40.70.60.20.30.2-0.30.30.3-0.30.50.40.81.1
Time >=10cm from walls, locomotor time 20.91.04.4-0.61.21.30.90.90.60.0-0.01.40.00.60.81.02.1
Bouts of movement, locomotor time 21.41.53.4-1.61.00.91.71.31.8-1.01.0-0.8-1.00.81.41.00.9
Total resting periods, locomotor time 21.51.63.6-1.81.21.01.81.51.9-1.01.0-0.7-1.00.81.51.10.9
Rest time, locomotor task time 20.20.20.5-0.70.60.30.60.70.40.2-0.20.50.2-0.30.70.10.1
Distance moved, locomotor task time 20.60.62.9-0.30.81.10.50.60.4-0.50.50.8-0.50.90.31.11.7
Vertical activity count, locomotor time 20.20.20.6-0.30.20.20.20.00.2-0.80.8-0.7-0.80.50.30.50.4
Weight adjusted by age0.70.81.90.9-1.2-1.2-0.6-1.1-0.40.4-0.4-0.30.4-0.6-1.2-1.0-1.4
Seeking ratio, delayed vs. immediate footshock0.10.20.5-0.30.50.60.30.60.20.1-0.10.70.1-0.20.30.30.5
Locomotion in novel chamber2.22.73.81.9-1.7-1.3-1.6-1.3-1.71.8-1.81.11.8-1.7-1.9-1.9-1.2
Locomotion in novel chamber post-restriction1.21.46.10.8-0.00.2-0.5-0.2-0.81.8-1.82.51.8-1.3-0.8-0.40.3
Progressive ratio0.40.51.7-0.50.90.90.50.60.20.5-0.51.10.5-0.30.50.51.3
Food seeking constrained by brief footshock0.60.83.10.30.40.1-0.7-0.4-1.21.1-1.11.81.1-1.3-0.1-0.00.6
Seeking ratio, punishment vs. effort0.00.10.10.10.0-0.3-0.3-0.3-0.3-0.30.30.0-0.3-0.1-0.00.0-0.3
Run reversals in cocaine runway, females0.50.51.00.7-1.0-0.8-0.6-0.8-0.20.2-0.2-0.90.2-0.0-0.7-0.8-1.0
Run reversals in cocaine runway, males0.40.40.8-0.80.90.60.50.40.4-0.70.7-0.1-0.70.30.80.90.7
Latency to leave start box in cocaine runway0.80.93.81.0-0.6-0.2-0.6-0.6-0.60.9-0.91.90.9-1.2-1.2-0.60.4
Latency to leave start box in cocaine runway, F0.30.31.70.5-0.20.1-0.1-0.1-0.10.5-0.51.30.5-0.6-0.7-0.20.6
Latency to leave start box in cocaine runway, M0.70.62.20.8-0.4-0.4-0.7-0.8-0.80.7-0.71.50.7-1.3-0.8-0.6-0.0
Cd content in liver0.20.30.7-0.50.40.20.10.00.3-0.70.7-0.8-0.70.50.50.50.4
Co content in liver0.91.14.10.7-1.4-1.5-0.8-1.3-0.3-0.60.6-2.0-0.6-0.0-0.9-0.9-1.1
Cu content in liver1.01.26.9-0.3-0.6-1.1-0.0-0.70.5-1.41.4-2.6-1.40.50.1-0.3-1.0
Fe content in liver3.44.06.2-2.11.61.41.81.62.1-2.52.5-2.0-2.51.92.11.81.6
K content in liver0.30.30.9-0.60.40.41.00.80.9-0.20.20.1-0.20.30.60.30.4
Mg content in liver0.80.91.6-1.00.70.61.20.91.3-1.11.1-0.5-1.10.80.90.80.6
Mn content in liver1.51.72.4-1.51.11.01.41.31.5-1.41.4-1.0-1.41.31.51.20.9
Na content in liver2.52.64.8-1.71.51.62.11.82.2-1.41.4-0.0-1.41.61.51.71.6
Rb content in liver0.10.10.9-0.20.40.40.30.30.10.2-0.21.00.2-0.40.10.30.4
Se content in liver15.018.132.1-4.42.82.13.82.94.7-5.75.7-5.2-5.74.54.13.52.2
Sr content in liver2.22.03.41.6-1.9-1.8-1.7-1.8-1.40.6-0.6-0.70.6-1.0-1.6-1.6-1.6
Zn content in liver8.29.013.4-3.22.32.23.22.83.5-3.43.4-2.7-3.43.73.12.82.1