Hub : Genes

Slc3a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018487 0.36 0.12 0.0e+00 0.2 0.17 0.18 0.19 3.1e-21 5.8e-19 4.2e-19 1.4e-20
2 BLA gene expression ENSRNOG00000018487 0.17 0.09 5.8e-05 0.09 0.07 0.07 0.08 1.4e-05 1.3e-04 1.5e-04 5.1e-05
3 BLA intron excision ratio chr1:205610437:205610982 0.06 0.04 1.8e-03 0.05 0.05 0.04 0.04 1.3e-03 1.5e-03 5.7e-03 2.3e-03
4 BLA intron excision ratio chr1:205610437:205618707 0.04 0.03 7.1e-03 0.03 0.03 0.02 0.02 1.3e-02 1.3e-02 1.9e-02 3.9e-02
5 Brain gene expression ENSRNOG00000018487 0.45 0.25 3.0e-14 0.15 0.12 0.15 0.16 1.7e-13 3.0e-11 5.3e-14 2.2e-14
6 Brain intron excision ratio chr1:205610437:205610982 0.05 0.03 5.8e-05 0.04 0.04 0.03 0.04 7.8e-05 4.6e-05 7.0e-04 1.0e-04
7 Brain intron excision ratio chr1:205610437:205618707 0.06 0.04 1.0e-05 0.06 0.06 0.04 0.06 5.0e-06 4.4e-06 4.7e-05 4.9e-06
8 Brain mRNA stability ENSRNOG00000018487 0.04 0.03 3.6e-03 0 0.02 0.02 0.01 1.3e-01 3.6e-03 2.4e-03 2.1e-02
9 Liver gene expression ENSRNOG00000018487 0.3 0.12 6.4e-14 0.11 0.11 0.1 0.11 4.8e-12 1.6e-12 2.8e-11 8.7e-12
10 NAcc gene expression ENSRNOG00000018487 0.21 0.12 7.0e-07 0.09 0.08 0.08 0.09 2.4e-07 2.1e-06 1.9e-06 2.7e-07
11 NAcc intron excision ratio chr1:205610437:205610982 0.06 0.03 3.2e-05 0.04 0.06 0.06 0.06 2.8e-04 1.9e-05 5.2e-05 3.0e-05
12 NAcc intron excision ratio chr1:205610437:205618707 0.06 0.04 9.6e-06 0.05 0.07 0.06 0.07 7.8e-05 8.0e-06 2.3e-05 1.1e-05
13 OFC gene expression ENSRNOG00000018487 0.29 0.15 6.5e-03 -0.01 -0 -0.01 0 9.9e-01 4.1e-01 6.6e-01 2.9e-01
14 PL gene expression ENSRNOG00000018487 0.2 0.12 1.3e-07 0.1 0.09 0.09 0.09 4.5e-08 4.0e-07 3.5e-07 1.3e-07
15 PL intron excision ratio chr1:205610437:205618707 0.03 0.02 4.0e-03 0.01 0.02 0.01 0.01 2.5e-02 1.8e-02 5.5e-02 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail3.812.318.04.24.2-2.63.34.1-3.23.1-0.74.04.2-3.03.14.04.23.1
BMI without tail1.32.83.41.81.7-1.51.71.6-1.71.7-1.01.71.9-1.61.61.71.91.8
Body weight2.811.718.22.92.9-4.04.32.6-4.34.2-0.32.33.0-4.14.12.63.04.2
Epididymis fat weight0.61.32.71.31.41.1-0.51.50.6-0.6-1.21.61.30.7-0.71.61.3-0.6
Glucose1.42.14.80.50.52.2-1.90.71.9-2.0-1.01.00.72.0-1.90.70.7-1.9
Heart weight0.60.82.40.70.80.9-0.80.70.8-0.8-1.51.20.61.0-1.10.90.6-0.6
Left kidney weight0.10.41.00.81.0-0.00.31.0-0.20.20.30.90.7-0.30.30.80.70.1
Right kidney weight0.20.61.41.01.0-0.40.61.2-0.40.40.91.00.8-0.60.71.10.80.2
Tail length0.51.53.3-0.6-0.7-1.81.5-1.0-1.61.6-0.1-1.1-0.8-1.61.5-0.8-0.81.7
Length with tail1.24.49.70.70.7-3.12.90.5-3.03.00.70.10.7-3.02.90.50.72.9
Length without tail1.22.74.81.11.2-2.22.21.1-2.22.20.70.71.2-2.22.20.91.22.0
Liver weight, left0.20.30.7-0.4-0.40.6-0.7-0.40.6-0.6-0.8-0.1-0.10.7-0.8-0.3-0.1-0.6
Liver weight, right0.50.82.21.01.0-0.10.31.0-0.40.3-0.71.31.5-0.10.11.11.50.4
Parametrial fat weight0.91.82.81.00.91.7-1.41.21.5-1.6-0.71.61.21.5-1.41.21.2-1.6
Retroperitoneal fat weight1.34.38.10.90.92.7-2.51.12.5-2.6-2.81.70.82.8-2.71.20.8-2.4
Intraocular pressure0.71.02.3-1.0-1.10.5-0.6-1.00.6-0.61.0-1.5-1.50.4-0.4-1.1-1.5-0.6
Extensor digitorum longus weight4.216.729.42.72.8-5.35.42.5-5.45.41.41.82.9-5.45.42.32.95.2
Soleus weight1.44.08.4-0.7-0.62.6-2.8-0.52.7-2.8-2.3-0.0-0.42.9-2.9-0.5-0.4-2.6
Tibialis anterior weight5.318.237.61.91.8-6.15.91.6-5.85.92.80.71.9-6.16.11.31.95.6
Tibia length0.92.612.80.80.9-1.51.81.1-1.61.63.60.30.8-2.12.20.70.81.2
Number of licking bursts0.00.00.10.00.1-0.2-0.00.10.0-0.0-0.20.10.00.0-0.00.10.0-0.0
Food consumed during 24 hour testing period0.20.20.6-0.7-0.50.5-0.4-0.40.4-0.40.8-0.5-0.30.3-0.3-0.6-0.3-0.5
Times rat made contact with spout0.20.30.6-0.6-0.6-0.70.3-0.8-0.40.4-0.6-0.6-0.5-0.30.2-0.6-0.50.5
Mean time between licks in bursts0.60.92.40.80.7-1.01.10.3-1.31.3-1.10.50.5-0.90.80.60.51.5
Mean num. licks in bursts0.20.20.6-0.6-0.70.1-0.2-0.80.1-0.1-0.4-0.6-0.50.2-0.2-0.7-0.5-0.0
Std. dev. time between licks in bursts0.10.11.60.20.10.2-0.2-0.10.0-0.0-1.30.20.00.3-0.40.20.00.2
Water consumed over 24 hours0.30.30.8-0.5-0.4-0.90.6-0.5-0.70.70.2-0.6-0.2-0.60.6-0.5-0.20.7
Indifference point 0 sec0.40.61.30.50.6-1.11.00.4-1.01.00.40.30.6-1.01.00.40.61.0
Indifference point AUC1.01.24.8-0.1-0.1-1.21.40.0-1.31.32.2-0.50.0-1.61.7-0.30.01.0
Indifference point function ln k1.82.512.80.80.71.5-1.70.51.6-1.6-3.61.20.22.1-2.21.00.2-1.1
Indifference point function log k1.82.512.80.80.71.5-1.70.51.6-1.6-3.61.20.22.1-2.21.00.2-1.1
Delay discounting total patch changes 0 sec0.30.51.50.20.3-1.20.90.1-1.01.00.10.00.4-0.90.90.20.41.1
Delay discounting total patch changes 12 sec3.14.19.00.20.3-3.02.80.2-2.72.72.2-0.20.7-3.03.0-0.10.72.5
Delay discounting total patch changes 18 sec0.30.51.9-0.5-0.4-0.80.6-0.4-0.60.61.4-0.7-0.1-0.80.8-0.7-0.10.5
Delay discounting total patch changes 24 sec4.55.611.31.41.5-3.43.21.3-3.13.11.00.81.5-3.23.21.21.53.0
Delay discounting total patch changes 6 sec0.81.32.30.70.8-1.51.40.6-1.41.40.20.61.1-1.41.40.61.11.4
Delay discounting time to switch 0 sec0.71.12.41.21.3-0.40.81.4-0.70.70.91.21.5-0.80.91.11.50.5
Delay discounting water rate 0 sec0.40.71.0-0.8-0.90.5-0.8-1.00.8-0.7-1.0-0.7-0.80.9-0.9-0.7-0.8-0.6
Delay discounting water rate 12 sec0.91.45.6-0.5-0.51.0-1.4-0.81.3-1.2-2.4-0.2-0.81.7-1.8-0.3-0.8-0.9
Delay discounting water rate 18 sec0.50.65.00.60.50.2-0.50.20.4-0.4-2.20.70.40.8-0.90.80.4-0.0
Delay discounting water rate 24 sec0.70.92.3-0.4-0.70.9-1.2-0.71.1-1.1-1.5-0.3-0.51.4-1.4-0.3-0.5-0.9
Delay discounting water rate 6 sec0.60.94.1-0.2-0.40.7-1.2-0.61.0-1.0-2.0-0.1-0.61.4-1.5-0.2-0.6-0.7
Locomotor activity0.61.04.9-0.7-0.70.6-1.0-0.90.8-0.8-2.2-0.5-0.81.1-1.2-0.6-0.8-0.5
Locomotor testing distance0.60.97.7-0.3-0.40.6-0.9-0.70.7-0.7-2.8-0.0-0.31.2-1.3-0.2-0.3-0.3
Locomotor testing rearing0.50.82.3-0.3-0.41.1-1.1-0.61.0-1.0-1.5-0.1-0.31.3-1.4-0.3-0.3-0.7
Light reinforcement 10.20.40.9-0.9-0.70.4-0.5-0.80.5-0.40.3-1.0-0.80.5-0.5-0.8-0.8-0.4
Light reinforcement 20.30.41.60.10.21.0-0.50.60.7-0.71.30.10.50.4-0.30.20.5-1.0
Reaction time number correct0.30.41.1-0.0-0.0-0.90.9-0.2-0.91.00.1-0.3-0.2-0.80.8-0.1-0.21.0
Reaction time mean minus median0.60.74.4-0.8-1.00.10.2-0.7-0.10.12.1-1.2-0.9-0.50.5-0.9-0.9-0.3
Reaction time mean minus median AUC0.91.12.8-1.4-1.60.1-0.1-1.40.1-0.11.3-1.7-1.3-0.10.1-1.4-1.3-0.3
Reaction time num false alarms0.40.53.1-0.7-0.70.1-0.4-1.00.3-0.3-1.8-0.4-0.70.5-0.7-0.7-0.70.0
Reaction time num false alarms AUC0.40.53.1-0.8-0.8-0.60.1-1.1-0.20.3-1.8-0.6-0.70.0-0.2-0.8-0.70.6
Reaction time trials correct on left0.30.41.1-0.0-0.0-0.90.9-0.2-0.91.00.1-0.3-0.2-0.80.8-0.1-0.21.0
Reaction time trials on left0.30.41.1-0.1-0.1-0.90.9-0.3-1.01.00.2-0.4-0.3-0.90.8-0.1-0.31.0
Reaction time mean0.50.72.5-0.9-1.00.7-0.4-0.80.5-0.51.6-1.0-1.00.2-0.2-0.9-1.0-0.7
Reaction time mean AUC0.60.82.4-0.9-1.00.9-0.6-0.80.6-0.61.5-1.0-1.00.4-0.3-0.8-1.0-0.8
Median of all reaction times0.10.21.5-0.4-0.50.4-0.1-0.30.1-0.11.2-0.4-0.5-0.00.1-0.3-0.5-0.3
Reaction time omissions0.70.92.2-1.3-1.4-0.2-0.1-1.40.00.00.2-1.5-1.4-0.10.1-1.3-1.4-0.0
Reaction time false alarm rate0.20.32.8-0.4-0.40.1-0.4-0.50.3-0.3-1.7-0.1-0.30.5-0.6-0.4-0.3-0.1
Reaction time premature initiation rate3.34.48.31.71.7-2.52.61.4-2.82.80.21.31.7-2.52.41.41.72.9
Reaction time premature initiations3.24.510.41.11.2-2.92.90.8-3.13.10.40.61.1-2.82.70.81.13.2
Std. dev. reaction times1.21.73.3-1.6-1.80.7-0.7-1.50.8-0.71.5-1.8-1.70.4-0.4-1.6-1.7-1.0
Reaction time trials completed0.30.41.1-0.1-0.1-0.90.9-0.3-1.01.00.2-0.4-0.3-0.90.8-0.1-0.31.0
Reaction time trials AUC0.20.30.9-0.00.0-0.80.8-0.2-0.90.90.0-0.3-0.2-0.70.7-0.0-0.21.0
Social response proportion0.10.10.20.30.2-0.10.40.2-0.40.40.20.10.1-0.40.30.20.10.5
Social responses0.30.41.2-0.9-1.0-0.30.1-1.1-0.20.2-0.2-1.0-0.6-0.10.0-1.0-0.60.2
Social time0.30.41.0-0.8-0.9-0.3-0.2-1.00.1-0.1-0.4-0.9-0.70.2-0.2-0.9-0.70.0
Conditioned locomotion0.40.50.90.30.3-0.90.90.2-0.90.9-0.80.30.6-0.90.80.30.60.9
Cocaine response after cond. corrected0.30.31.50.40.40.3-0.60.20.5-0.6-1.20.70.10.8-0.90.50.1-0.3
Cocaine response after cond. not corrected0.20.20.50.40.40.7-0.60.30.5-0.5-0.10.60.20.7-0.70.50.2-0.3
Cocaine response before conditioning0.60.78.2-0.3-0.30.50.4-0.1-0.30.42.9-0.7-0.3-0.50.6-0.3-0.30.1
Saline control response1.31.73.80.40.6-1.91.80.3-1.91.9-0.00.10.5-1.81.80.30.51.9
Condit. Reinf. active minus inactive responses0.50.61.4-0.8-0.70.8-0.8-0.50.9-0.91.2-0.6-0.50.7-0.6-0.8-0.5-1.0
Condit. Reinf. active-inactive response ratio0.60.61.9-0.00.11.1-0.90.41.1-1.11.30.20.10.8-0.70.00.1-1.4
Condit. Reinf. active responses0.10.10.3-0.4-0.40.0-0.1-0.30.1-0.10.6-0.4-0.20.0-0.0-0.4-0.2-0.2
Condit. Reinf. inactive responses0.20.20.7-0.3-0.3-0.50.4-0.5-0.50.6-0.9-0.4-0.2-0.30.2-0.3-0.20.7
Condit. Reinf. lever presses0.40.61.50.40.4-0.61.00.5-1.01.01.20.10.5-1.11.10.40.50.8
Condit. Reinf. lever reinforcers received0.10.20.8-0.5-0.5-0.20.2-0.4-0.10.20.9-0.6-0.3-0.30.3-0.5-0.30.0
Pavlov. Cond. lever latency0.40.60.9-0.9-0.90.3-0.8-0.90.8-0.8-0.4-0.6-0.80.8-0.9-0.8-0.8-0.7
Pavlov. Cond. magazine entry latency2.42.78.00.40.3-1.62.20.3-2.22.22.8-0.20.3-2.32.30.10.32.0
Pavlov. Cond. change in total contacts0.71.05.30.30.3-0.61.20.6-1.11.22.3-0.10.3-1.41.50.20.30.8
Pavlov. Cond. index score1.51.96.30.70.7-1.01.80.8-1.71.72.50.20.6-1.92.00.50.61.5
Pavlov. Cond. latency score1.41.85.70.80.8-0.91.71.0-1.61.62.40.30.8-1.81.80.70.81.4
Pavlov. Cond. lever contacts0.20.21.3-0.0-0.0-0.10.60.1-0.60.61.1-0.3-0.1-0.70.7-0.1-0.10.4
Pavlov. Cond. magazine entry number3.74.610.0-0.7-0.72.2-2.9-0.72.9-2.9-3.20.0-0.73.1-3.1-0.5-0.7-2.6
Pavlov. Cond. intertrial magazine entries1.21.52.8-0.9-0.91.2-1.6-0.81.7-1.7-0.5-0.6-1.01.6-1.6-0.7-1.0-1.6
Pavlov. Cond. lever-magazine prob. diff.1.62.17.10.70.6-1.11.90.8-1.81.92.70.10.6-2.02.10.50.61.6
Pavlov. Cond. response bias0.81.13.20.30.3-0.81.40.4-1.41.41.8-0.20.2-1.51.50.20.21.2
Conditioned reinforcement - actives1.71.73.6-0.9-0.91.8-1.7-0.61.8-1.80.7-0.7-0.91.5-1.5-0.7-0.9-1.9
Conditioned reinforcement - inactives0.50.61.60.40.31.3-0.90.61.1-1.10.60.60.20.9-0.80.50.2-1.2
Conditioned locomotion1.11.32.60.50.51.6-1.40.71.5-1.5-0.71.10.21.5-1.40.80.2-1.5
Intermittent access intake day 1-15 change2.22.22.9-1.6-1.61.5-1.5-1.41.5-1.51.4-1.7-1.41.3-1.2-1.5-1.4-1.7
Intermittent access intake escalation1.51.52.1-1.4-1.41.2-1.2-1.21.2-1.21.3-1.4-1.11.0-0.9-1.3-1.1-1.4
Intermittent access intake escalation 20.70.73.1-1.0-0.90.4-0.3-0.80.4-0.41.8-1.2-0.80.1-0.1-0.9-0.8-0.6
Intermitt. access day 1 inactive lever presses0.91.02.3-0.1-0.21.4-1.40.11.5-1.5-0.40.3-0.31.4-1.40.0-0.3-1.5
Intermitt. access day 15 inactive lever presses0.70.82.01.21.20.10.31.4-0.20.20.91.21.1-0.30.41.31.10.0
Intermitt. access escalation Index0.40.42.90.50.40.1-0.20.40.1-0.1-1.70.90.60.4-0.40.50.60.1
Intermittent access day 1 total infusions2.52.98.92.12.21.0-0.42.40.5-0.6-1.43.02.00.7-0.52.52.0-0.5
Intermittent access day 15 total infusions1.72.05.40.20.32.3-1.80.62.0-2.0-0.10.90.31.9-1.70.60.3-2.1
Intermittent access terminal intake (last 3 days)1.01.12.51.11.21.2-0.61.50.8-0.80.61.61.20.6-0.41.41.2-1.0
Intermittent access total infusions1.21.33.11.21.21.3-0.71.50.9-0.9-0.11.81.20.8-0.71.51.2-1.0
Intermittent access day 1 locomotion3.43.510.62.52.50.20.32.6-0.20.1-1.83.32.40.00.12.82.40.3
Intermittent access day 15 total locomotion0.90.92.51.31.30.6-0.11.50.3-0.30.01.61.20.2-0.11.51.2-0.4
Intermittent access total locomotion3.13.59.72.62.60.50.22.9-0.0-0.1-0.13.12.5-0.10.22.82.5-0.1
Intermittent access standard deviation1.61.72.5-1.3-1.31.5-1.4-1.11.5-1.50.6-1.2-1.21.3-1.3-1.1-1.2-1.6
Cocaine induced anxiety0.20.21.20.20.2-0.30.50.2-0.40.41.1-0.00.4-0.50.60.10.40.3
Post-drug Anxiety0.40.43.40.00.0-0.60.70.1-0.60.61.8-0.4-0.1-0.80.9-0.1-0.10.4
Baseline Anxiety0.60.61.40.10.1-1.21.1-0.0-1.11.10.5-0.3-0.3-1.11.0-0.1-0.31.1
Lifetime Intake1.11.23.41.21.31.2-0.71.40.8-0.8-0.81.81.10.8-0.71.51.1-0.8
Incentive Sensitization - Responses0.40.41.10.90.90.00.31.0-0.20.20.80.90.7-0.30.41.00.70.1
Incentive Sensitization - Breakpoint0.40.41.10.90.90.20.21.1-0.10.10.80.90.7-0.20.31.00.7-0.0
Progressive ratio test 1 active lever presses1.11.12.6-0.3-0.31.6-1.5-0.11.5-1.6-0.50.2-0.51.5-1.4-0.1-0.5-1.5
Progressive ratio test 1 breakpoint1.31.32.9-0.4-0.41.7-1.6-0.31.7-1.7-0.40.0-0.61.6-1.5-0.2-0.6-1.6
Progressive ratio test 1 inactive lever presses0.40.41.00.90.8-0.30.40.8-0.40.4-0.81.00.6-0.30.30.90.60.5
Progressive ratio test 2 active lever presses0.91.02.60.30.31.6-1.30.61.4-1.40.00.80.31.3-1.20.60.3-1.5
Progressive ratio test 2 breakpoint1.51.64.2-0.2-0.22.0-1.80.01.9-1.90.00.3-0.31.7-1.60.0-0.3-2.0
Progressive ratio test 2 inactive lever presses0.70.81.70.90.91.1-0.71.20.8-0.90.21.30.70.7-0.61.20.7-0.9
Total sessions with >9 infusions1.31.43.10.90.91.4-1.01.01.1-1.1-1.81.70.91.2-1.21.20.9-0.9
Short access day 1 total inactive lever presses0.90.92.51.11.00.9-0.61.10.7-0.7-1.51.60.70.8-0.81.20.7-0.6
Short access day 10 total inactive lever presses1.31.44.7-0.3-0.41.3-1.5-0.31.4-1.5-2.20.3-0.51.7-1.7-0.2-0.5-1.2
Short access day 1 total infusions0.80.92.30.80.81.0-0.70.90.7-0.8-1.51.40.80.9-0.81.00.8-0.6
Short access day 10 total infusions2.02.26.92.02.00.50.02.20.1-0.2-1.22.61.70.2-0.12.31.7-0.1
Short access total infusions1.21.34.41.41.50.6-0.21.60.3-0.3-1.62.11.10.5-0.41.71.1-0.2
Short access day 1 locomotion2.02.15.71.91.9-0.20.61.9-0.60.5-1.32.41.9-0.40.42.11.90.6
Short access day 10 total locomotion1.41.54.01.71.6-0.20.41.8-0.40.3-0.82.01.7-0.30.31.81.70.4
Short access total locomotion2.72.76.72.12.2-0.50.92.2-0.80.7-1.22.62.2-0.60.72.32.20.8
Compulsive drug intake1.01.02.2-0.6-0.5-1.41.0-0.9-1.31.3-1.1-0.8-0.4-1.00.8-0.7-0.41.5
One hour access (0.3 mA shock)2.02.35.30.00.12.3-2.00.42.2-2.2-0.70.90.22.1-2.00.40.2-2.2
One hour access (shock baseline)2.93.38.5-0.4-0.42.8-2.50.12.7-2.80.60.3-0.32.4-2.3-0.0-0.3-2.9
Number of responses in last shaping day0.10.11.20.10.1-0.10.1-0.0-0.10.1-1.10.30.10.0-0.10.20.10.3
Context. condit. distance diff. score0.40.51.20.90.90.1-0.30.80.3-0.4-0.91.10.90.5-0.51.10.9-0.2
Locomotion velocity, session 10.20.31.10.70.6-0.50.20.4-0.30.3-1.00.60.3-0.10.00.70.30.5
Locomotion distance, session 11.11.42.11.41.4-1.31.11.2-1.11.0-0.71.31.4-0.90.91.41.41.2
Locomotion velocity, session 21.82.23.81.11.0-2.01.90.9-1.91.80.80.81.1-1.91.90.91.11.8
Locomotion distance, session 20.30.41.00.50.4-1.00.60.3-0.60.6-0.90.50.6-0.50.50.50.60.8
Locomotion velocity, session 32.02.34.62.02.0-0.80.91.8-0.90.8-0.92.12.1-0.70.71.92.10.9
Locomotion distance, session 30.10.10.50.20.3-0.30.30.1-0.30.30.00.40.7-0.20.20.20.70.4
Stereotopy head waving bouts, day 31.82.25.31.92.0-0.30.11.9-0.0-0.1-1.92.32.00.1-0.02.02.00.1
Stereotopy head waving duration, day 30.81.04.01.21.3-0.4-0.11.20.2-0.2-2.01.40.90.2-0.21.30.9-0.1
Locomotion velocity, session 70.40.41.30.80.7-0.10.00.80.0-0.1-0.41.01.10.1-0.00.91.1-0.1
Locomotion distance, session 70.50.61.61.00.9-0.2-0.00.9-0.0-0.0-1.01.31.20.2-0.21.11.20.2
Stereotopy head waving bouts, day 70.10.10.40.60.5-0.40.30.6-0.10.10.10.40.3-0.40.40.50.30.0
Stereotopy head waving duration, day 71.01.32.70.90.9-1.31.50.8-1.41.40.50.30.4-1.61.60.80.41.3
Locomotion velocity, session 80.10.21.4-0.1-0.2-0.5-0.1-0.40.0-0.0-1.2-0.1-0.40.2-0.3-0.1-0.40.2
Locomotion distance, session 80.60.92.21.31.3-0.1-0.21.20.3-0.3-0.91.51.30.4-0.31.41.3-0.2
Degree of sensitization distance1.51.53.51.81.7-0.10.21.8-0.10.0-1.01.91.60.00.01.81.60.1
Degree of sensitization stereotypy0.40.41.20.40.3-0.70.90.4-0.80.81.0-0.00.1-1.01.10.30.10.6
Condit. Reinf. active minus inactive responses0.60.71.30.50.5-1.01.10.4-1.11.11.10.20.3-1.11.10.40.31.0
Condit. Reinf. active-inactive response ratio0.30.30.6-0.3-0.2-0.80.6-0.4-0.60.60.4-0.6-0.7-0.60.6-0.3-0.70.6
Condit. Reinf. active responses0.91.12.51.01.0-0.81.11.0-1.01.01.60.70.9-1.21.20.90.90.9
Condit. Reinf. inactive responses0.60.71.81.20.90.60.11.20.0-0.01.31.01.3-0.10.21.11.3-0.2
Incentive salience index mean1.31.52.01.31.3-1.11.41.2-1.41.41.30.91.0-1.41.41.11.01.3
Condit. Reinf. lever presses1.21.62.31.51.5-0.71.21.5-1.21.11.41.21.3-1.11.21.51.31.1
Time in familiar zone, hab. session 10.40.40.80.70.70.20.40.7-0.50.40.80.70.9-0.30.30.80.90.4
Time in novel zone, hab. session 11.11.12.5-0.9-0.80.9-1.2-0.91.2-1.2-1.6-0.6-0.81.3-1.3-0.8-0.8-1.0
Total zone transitions, hab. session 10.10.21.00.10.1-1.00.60.0-0.60.60.2-0.0-0.1-0.60.60.1-0.10.6
Total locomotion distance, hab. session 10.30.51.30.90.9-0.2-0.11.00.1-0.20.21.11.10.1-0.10.91.1-0.2
Locomotion velocity, hab. session 10.30.40.80.70.7-0.70.40.8-0.40.30.70.80.9-0.40.50.70.90.3
Time in familiar zone, hab. session 20.60.61.4-1.1-1.10.9-0.6-1.20.4-0.40.2-0.9-0.60.6-0.7-1.0-0.6-0.3
Time in novel zone, hab. session 20.90.91.61.31.2-1.00.91.2-0.80.7-0.21.00.9-0.80.91.20.90.7
Total zone transitions, hab. session 21.52.02.91.41.4-1.51.61.2-1.61.60.61.11.5-1.51.51.31.51.7
Total locomotion distance, hab. session 20.71.02.41.21.2-0.60.61.1-0.60.60.71.31.5-0.50.51.21.50.7
Locomotion velocity, hab. session 20.71.02.41.31.3-0.50.41.3-0.40.40.71.41.5-0.30.31.31.50.4
Novel to familiar place preference ratio1.11.12.60.80.8-1.31.50.8-1.31.40.30.40.6-1.61.60.60.61.2
Novelty place preference0.60.61.50.70.6-0.91.10.7-1.01.00.20.30.4-1.21.20.50.40.8
Time in novel zone, NPP test0.70.81.70.70.7-1.01.20.7-1.11.10.00.40.6-1.21.30.60.61.0
Total zone transitions, NPP test0.81.12.50.70.6-1.61.40.5-1.41.40.70.40.7-1.41.30.60.71.5
Total locomotion distance, NPP test0.30.40.90.70.7-0.60.40.6-0.40.40.50.91.0-0.30.30.71.00.5
Locomotion velocity, NPP test0.10.10.30.30.3-0.60.20.2-0.20.20.50.50.6-0.20.10.30.60.3
Pavlov. Cond. lever latency1.62.12.6-1.6-1.60.9-1.4-1.61.4-1.3-1.6-1.3-1.61.4-1.4-1.5-1.6-1.2
Pavlov. Cond. magazine entry latency1.21.65.21.11.1-0.51.21.2-1.11.12.31.01.5-1.21.31.01.50.9
Pavlov. Cond. change in total contacts0.60.65.70.60.60.10.50.8-0.30.32.40.40.7-0.60.70.50.70.1
Pavlov. Cond. index score0.50.74.40.50.5-0.40.80.6-0.80.82.10.30.7-0.90.90.40.70.6
Pavlov. Cond. latency score0.60.83.00.70.7-0.40.80.8-0.80.81.70.60.9-0.80.90.70.90.7
Pavlov. Cond. lever contacts0.60.71.50.90.9-0.20.60.9-0.60.61.20.81.1-0.60.60.81.10.5
Pavlov. Cond. magazine entry number0.60.76.90.20.20.3-0.70.00.6-0.7-2.60.3-0.00.9-0.90.3-0.0-0.4
Pavlov. Cond. intertrial magazine entries0.50.62.0-0.8-0.90.1-0.2-0.80.2-0.21.4-1.1-1.1-0.00.1-0.9-1.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.70.84.80.50.5-0.50.90.6-0.90.92.20.40.8-1.01.10.40.80.6
Pavlov. Cond. response bias0.70.96.60.40.5-0.30.90.6-0.80.82.60.30.6-1.01.00.40.60.6
Bone: apparent density0.61.01.71.21.3-0.60.81.3-0.80.70.31.11.2-0.80.81.21.20.7
Bone surface1.62.84.11.71.7-1.41.91.8-1.71.71.71.21.6-1.92.01.51.61.5
Bone volume0.91.52.51.41.5-0.71.21.6-1.01.01.41.01.3-1.21.31.31.30.8
Bone: connectivity density1.72.73.41.71.7-1.41.81.7-1.81.71.31.41.6-1.81.81.51.61.7
Bone: cortical apparent density0.40.51.0-0.7-0.7-1.00.6-0.8-0.60.70.6-0.9-0.8-0.70.7-0.8-0.80.6
Bone: cortical area0.50.81.40.70.8-0.81.10.8-1.01.00.90.50.9-1.11.20.60.90.9
Bone: cortical porosity0.30.40.8-0.8-0.9-0.1-0.4-0.90.4-0.40.2-0.8-0.70.3-0.3-0.8-0.7-0.4
Bone: cortical porosity0.30.40.8-0.8-0.9-0.4-0.1-0.90.0-0.00.1-0.9-0.8-0.10.0-0.9-0.8-0.0
Bone: cortical thickness1.42.45.2-0.4-0.4-2.32.1-0.7-2.22.20.8-0.9-0.4-2.22.1-0.7-0.42.2
Bone: cortical thickness0.30.40.9-0.6-0.5-0.90.7-0.7-0.80.8-0.4-0.5-0.1-0.70.6-0.6-0.10.9
Bone: cortical tissue density0.50.71.2-0.8-0.8-1.10.7-0.9-0.70.70.7-0.9-0.8-0.80.7-0.8-0.80.7
Bone: elastic displacement0.91.03.3-1.2-1.20.4-0.8-1.30.7-0.7-1.8-0.9-0.90.8-0.9-1.1-0.9-0.5
Bone: elastic work0.60.82.5-0.1-0.0-1.31.0-0.3-1.11.1-1.6-0.00.2-1.00.9-0.10.21.3
Bone: endosteal estimation1.63.46.72.02.21.7-1.02.41.2-1.3-1.12.62.41.3-1.12.32.4-1.4
Bone: endosteal perimeter1.73.65.51.91.92.2-1.52.31.8-1.8-0.82.32.11.7-1.42.02.1-2.0
Bone: final force1.72.84.11.61.6-1.62.01.6-1.91.91.11.21.6-2.02.01.51.61.8
Bone: final moment1.62.73.91.51.5-1.61.91.5-1.91.81.21.11.6-1.92.01.41.61.7
Bone: marrow area1.63.56.62.02.11.8-1.22.31.3-1.4-1.22.62.31.4-1.22.22.3-1.5
Bone: maximum diameter0.40.71.71.11.1-0.20.41.3-0.30.30.81.01.1-0.50.61.11.10.1
Bone: maximum force3.25.67.62.62.7-1.72.42.7-2.22.21.42.22.7-2.32.52.62.72.0
Bone: maximum moment3.05.16.82.52.6-1.62.32.6-2.22.11.42.12.6-2.32.42.42.62.0
Bone: minimum diameter1.42.75.62.02.11.2-0.62.30.7-0.8-1.12.42.30.7-0.62.12.3-0.9
Bone: periosteal estimation0.91.94.51.81.90.40.12.10.0-0.1-0.12.02.1-0.00.21.82.1-0.3
Bone: periosteal perimeter0.40.71.81.11.10.40.01.30.1-0.20.31.21.30.00.11.11.3-0.4
Bone: post-yield work2.43.37.82.42.51.0-0.12.80.3-0.41.92.52.40.20.02.52.4-0.6
Bone: stiffness0.81.22.51.11.2-0.71.11.3-1.01.01.60.91.2-1.21.31.01.20.8
Bone: tissue strength0.20.20.7-0.1-0.20.8-0.5-0.10.4-0.40.2-0.4-0.50.5-0.5-0.1-0.5-0.4
Bone: trabecular number1.01.52.41.51.5-0.91.21.6-1.11.10.71.21.4-1.21.31.41.41.0
Bone: trabecular spacing0.60.81.7-1.2-1.20.7-0.7-1.30.6-0.50.1-1.0-1.10.7-0.8-1.2-1.1-0.4
Bone: trabecular thickness0.20.20.60.0-0.00.7-0.50.20.6-0.60.30.20.20.5-0.40.00.2-0.8
Bone: trabecular tissue density3.34.67.3-1.5-1.72.1-2.7-1.52.7-2.7-1.4-1.4-2.22.7-2.7-1.3-2.2-2.5
Breakpoint value in progressive ratio session1.01.23.5-0.5-0.6-1.31.2-0.5-1.21.21.9-1.1-0.2-1.41.4-0.7-0.21.0
Distance traveled before self-admin1.21.32.90.40.4-1.41.50.5-1.41.41.7-0.00.5-1.61.70.30.51.2
Distance traveled after self-admin0.20.31.6-0.4-0.4-0.30.4-0.3-0.40.41.3-0.7-0.4-0.50.5-0.4-0.40.2
Delta time in closed arm before/after self-admin2.12.03.61.21.2-1.81.50.8-1.61.6-1.71.31.4-1.31.21.21.41.9
Delta time in open arm before/after self-admin0.80.84.00.10.1-0.91.10.2-0.91.02.0-0.3-0.0-1.31.3-0.1-0.00.7
Diff in mean of infusions in LGA sessions1.01.12.3-0.7-0.7-1.51.2-0.8-1.21.21.1-1.2-0.5-1.31.3-0.9-0.51.2
Extinction: sum of active levers before priming2.12.14.40.60.5-2.02.00.5-2.02.01.5-0.00.5-2.12.10.40.51.8
Active lever presses in extinction session 61.41.45.5-0.2-0.3-1.31.4-0.2-1.41.42.4-0.9-0.1-1.61.7-0.4-0.11.1
Delta distance traveled before/after self-admin0.40.50.8-0.5-0.60.7-0.8-0.60.7-0.7-0.8-0.4-0.70.9-0.9-0.5-0.7-0.6
Delta ambulatory time before/after self-admin0.70.81.4-0.7-0.80.8-1.1-0.80.9-0.9-1.1-0.5-0.91.1-1.2-0.7-0.9-0.8
Time in closed arm before self-admin0.10.10.90.0-0.00.5-0.20.20.3-0.31.0-0.10.00.1-0.0-0.00.0-0.5
Time in closed arm after self-admin0.30.31.70.20.10.6-0.60.10.5-0.6-1.30.50.40.7-0.80.20.4-0.4
Time in open arm before self-admin0.70.76.1-0.4-0.40.2-0.8-0.60.6-0.6-2.5-0.0-0.41.0-1.1-0.2-0.4-0.2
Time in open arm after self-admin0.40.41.0-0.9-0.9-0.40.0-1.0-0.10.10.1-1.0-1.0-0.10.0-0.9-1.00.1
Sum of active levers in priming session hrs 5-61.41.48.9-1.1-1.1-0.50.6-0.9-0.40.53.0-1.7-0.9-0.91.0-1.3-0.90.1
Time to tail flick, vehicle, before self-admin1.51.52.71.61.6-0.70.91.6-0.80.80.21.61.6-0.80.91.61.60.7
Time to tail flick, vehicle, after self-admin1.01.01.61.11.1-0.90.90.9-0.90.9-1.21.11.3-0.70.71.01.31.0
Time to tail flick, test, before self-admin2.42.44.81.91.9-0.90.91.7-0.90.9-1.52.22.1-0.70.72.02.11.0
Time to tail flick, test, after self-admin0.10.10.1-0.3-0.30.2-0.3-0.30.3-0.3-0.0-0.3-0.20.3-0.3-0.3-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.1-0.0-0.20.1-0.2-0.20.2-0.8-0.00.1-0.0-0.0-0.10.10.3
Delta time to tail flick, test, before/after SA2.21.94.6-1.8-1.80.4-0.6-1.70.6-0.51.4-2.1-1.90.3-0.4-1.9-1.9-0.7
Ambulatory time before self-admin1.01.14.80.10.2-1.01.30.3-1.21.22.2-0.40.4-1.51.50.00.40.9
Ambulatory time after self-admin0.20.21.80.20.2-0.00.40.3-0.30.31.3-0.00.3-0.50.50.20.30.1
Total heroin consumption1.92.35.0-0.6-0.7-2.21.8-0.8-1.91.91.7-1.4-0.5-2.02.0-0.9-0.51.8
Area under the delay curve0.50.51.11.00.9-0.30.30.9-0.30.3-0.81.10.8-0.20.21.00.80.4
Delay disc. indifference point, 0s delay1.01.13.21.31.20.1-0.11.20.1-0.1-1.81.71.20.3-0.31.41.20.1
Delay disc. indifference point, 16s delay0.50.51.01.00.9-0.20.40.9-0.40.30.20.90.9-0.40.40.90.90.3
Delay disc. indifference point, 2s delay0.40.41.30.90.80.4-0.20.90.3-0.3-0.41.10.80.4-0.31.00.8-0.3
Delay disc. indifference point, 24s delay0.20.20.60.40.6-0.50.40.3-0.50.5-0.80.50.4-0.30.30.40.40.6
Delay disc. indifference point, 4s delay1.01.11.81.21.2-1.00.81.0-0.90.8-1.31.31.0-0.60.61.21.01.1
Delay disc. indifference point, 8s delay0.20.32.40.20.20.1-0.40.10.4-0.4-1.60.4-0.00.6-0.60.2-0.0-0.2
Delay discount exponential model param0.40.41.0-0.9-0.90.3-0.3-0.80.3-0.30.8-1.0-0.70.1-0.1-0.9-0.7-0.4
Delay discount hyperbolic model param0.50.51.2-1.0-0.90.3-0.3-0.90.3-0.30.8-1.1-0.80.2-0.2-1.0-0.8-0.4
Fecal boli incidents, locomotor time 10.40.41.6-0.4-0.30.9-0.6-0.00.8-0.81.3-0.4-0.40.5-0.4-0.4-0.4-1.0
Change in fecal boli incidents, locomotor task0.60.64.60.50.40.1-0.50.30.4-0.4-2.20.80.50.7-0.80.60.5-0.1
Time >=10cm from walls, locomotor time 11.31.33.30.30.51.8-1.40.81.6-1.70.20.70.31.4-1.30.50.3-1.8
Bouts of movement, locomotor time 12.12.36.2-2.1-1.9-0.1-0.2-2.00.1-0.11.6-2.5-2.1-0.10.1-2.1-2.1-0.2
Total resting periods, locomotor time 11.41.64.2-1.7-1.5-0.1-0.1-1.50.1-0.01.7-2.1-1.7-0.20.2-1.8-1.7-0.2
Rest time, locomotor task time 11.31.41.9-1.2-1.21.1-1.4-1.11.4-1.4-0.5-0.9-0.91.3-1.4-1.1-0.9-1.3
Distance moved, locomotor task time 10.40.50.90.90.8-0.40.70.9-0.60.60.10.80.6-0.60.61.00.60.6
Vertical activity count, locomotor time 10.30.30.70.0-0.00.8-0.80.10.8-0.8-0.60.20.00.8-0.80.20.0-0.7
Time >=10cm from walls, locomotor time 20.50.51.7-0.8-0.60.7-0.5-0.50.6-0.61.3-0.9-0.80.4-0.3-0.6-0.8-0.8
Bouts of movement, locomotor time 20.60.71.5-0.00.0-1.11.1-0.1-1.21.20.9-0.4-0.1-1.21.2-0.1-0.11.1
Total resting periods, locomotor time 20.30.30.7-0.0-0.0-0.70.8-0.1-0.80.80.7-0.4-0.1-0.80.8-0.2-0.10.7
Rest time, locomotor task time 21.82.14.3-0.7-0.71.8-2.0-0.62.0-2.0-1.2-0.1-0.52.1-2.1-0.7-0.5-1.9
Distance moved, locomotor task time 20.40.51.0-0.6-0.5-0.50.6-0.6-0.60.61.0-0.9-0.7-0.70.7-0.5-0.70.5
Vertical activity count, locomotor time 20.50.61.7-1.1-1.1-0.1-0.2-1.30.1-0.1-0.5-1.2-1.00.2-0.3-1.0-1.00.0
Weight adjusted by age1.11.32.30.90.9-0.91.40.9-1.31.31.40.50.9-1.51.50.90.91.2
Seeking ratio, delayed vs. immediate footshock0.10.10.20.40.4-0.20.20.4-0.20.2-0.20.40.3-0.10.10.50.30.2
Locomotion in novel chamber1.21.54.50.10.12.1-1.60.51.7-1.80.20.50.41.6-1.50.40.4-1.9
Locomotion in novel chamber post-restriction1.61.93.9-0.8-0.91.4-1.9-0.72.0-2.0-0.8-0.4-0.81.9-1.9-0.6-0.8-1.9
Progressive ratio0.20.20.60.60.60.20.10.8-0.10.10.20.60.8-0.10.20.70.8-0.0
Food seeking constrained by brief footshock0.10.10.9-0.1-0.1-0.0-0.2-0.20.1-0.1-0.90.0-0.10.3-0.4-0.1-0.1-0.0
Seeking ratio, punishment vs. effort0.20.21.5-0.3-0.4-0.3-0.2-0.60.1-0.1-1.2-0.2-0.50.3-0.4-0.4-0.50.2
Run reversals in cocaine runway, females2.72.74.31.81.9-1.31.31.6-1.41.4-2.12.11.9-1.01.01.91.91.6
Run reversals in cocaine runway, males0.60.60.8-0.8-0.80.5-0.8-0.70.8-0.8-0.9-0.6-0.70.8-0.9-0.7-0.7-0.7
Latency to leave start box in cocaine runway0.60.61.41.01.10.6-0.31.10.4-0.4-0.61.20.90.5-0.41.10.9-0.4
Latency to leave start box in cocaine runway, F0.10.10.30.50.5-0.00.10.5-0.10.1-0.10.50.4-0.10.10.50.40.1
Latency to leave start box in cocaine runway, M1.51.53.20.10.11.8-1.70.21.7-1.7-0.90.4-0.01.8-1.80.3-0.0-1.6
Cd content in liver0.80.91.8-0.4-0.41.2-1.2-0.21.3-1.3-1.0-0.4-0.71.2-1.2-0.2-0.7-1.4
Co content in liver2.63.14.8-2.1-1.91.1-1.7-2.21.5-1.4-1.3-1.8-2.21.7-1.8-1.8-2.2-1.2
Cu content in liver0.20.20.7-0.1-0.1-0.80.5-0.2-0.50.5-0.5-0.3-0.5-0.50.4-0.1-0.50.7
Fe content in liver0.00.00.10.10.20.1-0.10.20.1-0.2-0.20.0-0.20.00.00.1-0.2-0.2
K content in liver1.81.83.01.41.7-0.91.21.6-1.21.10.41.41.7-1.21.21.61.71.0
Mg content in liver1.61.73.41.61.8-0.70.91.8-0.80.7-0.01.61.8-0.70.81.81.80.7
Mn content in liver1.11.22.80.50.6-1.31.50.6-1.51.51.10.00.4-1.61.70.40.41.3
Na content in liver0.40.40.80.40.7-0.60.80.6-0.70.70.10.40.7-0.90.90.50.70.6
Rb content in liver0.70.93.10.20.41.1-1.20.31.1-1.2-1.80.60.21.3-1.30.50.2-1.0
Se content in liver0.20.20.50.40.6-0.10.40.7-0.20.20.70.20.3-0.50.60.40.3-0.1
Sr content in liver2.72.45.50.20.2-2.32.20.1-2.12.21.4-0.20.2-2.32.30.10.22.0
Zn content in liver2.62.95.40.91.0-2.32.20.9-2.12.11.50.71.4-2.32.30.81.42.0