Hub : Genes

Anapc10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000018296 0.07 0.04 1.6e-04 0.03 0.03 0.02 0.02 2.9e-04 6.4e-04 9.3e-04 1.7e-03
2 BLA gene expression ENSRNOG00000018296 0.16 0.07 8.2e-08 0.08 0.14 0.12 0.11 4.7e-05 5.1e-08 3.7e-07 1.7e-06
3 Brain gene expression ENSRNOG00000018296 0.21 0.08 0.0e+00 0.17 0.2 0.18 0.2 8.3e-16 4.4e-18 8.9e-17 4.5e-18
4 IL gene expression ENSRNOG00000018296 0.32 0.16 5.8e-04 0.12 0.07 0.08 0.06 8.9e-04 8.1e-03 6.0e-03 1.4e-02
5 NAcc gene expression ENSRNOG00000018296 0.23 0.09 4.4e-14 0.2 0.18 0.19 0.2 1.7e-14 3.1e-13 4.8e-14 1.8e-14
6 NAcc mRNA stability ENSRNOG00000018296 0.05 0.03 1.2e-03 0.01 0.02 0.01 0.01 1.1e-01 6.3e-03 2.7e-02 5.3e-02
7 OFC gene expression ENSRNOG00000018296 0.23 0.12 3.5e-04 0.1 0.1 0.1 0.11 2.9e-03 2.8e-03 2.9e-03 1.4e-03
8 PL gene expression ENSRNOG00000018296 0.23 0.09 2.6e-13 0.15 0.17 0.15 0.16 1.4e-11 1.3e-12 9.0e-12 3.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.44.510.0-0.62.52.31.51.33.22.71.6
BMI without tail0.30.72.61.60.1-0.3-1.1-1.10.4-0.0-0.8
Body weight1.25.28.22.3-2.2-2.1-2.0-2.7-1.2-2.4-2.9
Epididymis fat weight1.74.06.51.7-2.0-1.8-2.2-1.9-1.4-2.2-2.6
Glucose0.30.42.0-0.6-0.20.0-0.20.5-1.4-0.60.3
Heart weight1.21.83.41.9-0.5-0.5-1.1-1.61.8-0.1-1.8
Left kidney weight0.92.65.02.0-1.3-1.3-1.3-1.7-0.8-1.7-2.2
Right kidney weight0.41.22.81.7-0.4-0.5-0.6-1.0-1.1-1.2-1.4
Tail length5.416.219.04.0-4.0-4.0-3.8-4.2-3.4-4.4-4.3
Length with tail5.419.626.03.5-4.9-4.6-3.7-4.4-3.9-5.1-5.0
Length without tail0.71.53.3-0.1-1.8-1.2-0.6-0.9-1.0-1.7-1.5
Liver weight, left2.33.87.31.7-1.8-1.7-1.4-1.8-2.3-2.7-1.8
Liver weight, right0.10.10.6-0.00.30.40.20.4-0.8-0.30.1
Parametrial fat weight0.40.81.40.5-1.2-0.8-0.6-0.9-0.6-1.0-1.2
Retroperitoneal fat weight1.44.68.81.3-2.2-1.9-1.5-1.5-3.0-3.0-2.1
Intraocular pressure0.20.31.40.50.60.20.2-0.41.20.60.2
Extensor digitorum longus weight0.73.06.0-0.32.42.01.71.41.21.91.9
Soleus weight1.13.24.81.9-1.8-1.9-1.8-2.2-0.6-1.7-1.9
Tibialis anterior weight0.10.31.21.10.40.00.1-0.51.00.4-0.1
Tibia length0.10.20.5-0.30.40.50.70.5-0.20.00.3
Number of licking bursts1.21.42.01.3-1.2-1.3-1.4-1.3-0.2-1.0-1.4
Food consumed during 24 hour testing period0.50.63.30.7-0.3-0.5-0.2-0.2-1.8-0.9-0.1
Times rat made contact with spout0.20.30.90.40.50.20.00.21.00.70.3
Mean time between licks in bursts0.20.30.90.9-0.2-0.3-0.5-0.5-0.3-0.6-0.6
Mean num. licks in bursts0.91.11.6-0.71.21.10.91.10.81.21.3
Std. dev. time between licks in bursts1.11.31.71.3-1.0-1.1-1.2-1.2-0.7-1.2-1.3
Water consumed over 24 hours0.10.10.20.40.40.10.10.2-0.10.30.3
Indifference point 0 sec0.71.12.81.7-0.5-0.8-0.9-1.4-0.3-0.9-1.1
Indifference point AUC0.00.00.10.20.10.00.3-0.00.20.10.2
Indifference point function ln k0.40.51.00.7-0.5-0.5-1.0-0.80.3-0.5-1.0
Indifference point function log k0.40.51.00.7-0.5-0.5-1.0-0.80.3-0.5-1.0
Delay discounting total patch changes 0 sec0.81.32.91.7-0.7-1.0-1.0-1.5-0.4-1.0-1.3
Delay discounting total patch changes 12 sec0.20.31.81.30.1-0.2-0.1-0.6-0.3-0.3-0.3
Delay discounting total patch changes 18 sec1.01.32.51.6-1.0-1.3-0.9-1.0-1.0-1.3-1.0
Delay discounting total patch changes 24 sec1.01.23.11.8-0.7-1.0-0.7-1.3-1.0-1.0-1.0
Delay discounting total patch changes 6 sec0.20.31.01.0-0.2-0.3-0.5-0.7-0.0-0.4-0.6
Delay discounting time to switch 0 sec0.30.40.8-0.70.50.50.80.9-0.20.40.6
Delay discounting water rate 0 sec0.20.30.70.4-0.4-0.3-0.5-0.6-0.9-0.8-0.4
Delay discounting water rate 12 sec0.20.31.4-0.00.20.1-0.8-0.21.20.5-0.2
Delay discounting water rate 18 sec0.81.13.01.2-0.6-1.0-1.7-1.2-0.1-0.7-1.1
Delay discounting water rate 24 sec0.10.10.5-0.30.20.1-0.70.00.50.10.3
Delay discounting water rate 6 sec0.20.31.1-0.20.60.3-0.10.5-1.0-0.20.7
Locomotor activity0.81.22.0-0.91.01.40.90.81.41.30.9
Locomotor testing distance0.20.30.7-0.30.50.60.30.30.80.70.4
Locomotor testing rearing1.72.73.4-1.41.71.81.81.81.11.61.7
Light reinforcement 10.40.83.81.10.6-0.10.70.1-1.9-0.50.7
Light reinforcement 20.70.94.70.70.3-0.30.60.3-2.2-1.00.4
Reaction time number correct0.20.30.50.6-0.5-0.5-0.6-0.70.5-0.1-0.7
Reaction time mean minus median0.10.10.8-0.9-0.30.10.00.30.10.4-0.1
Reaction time mean minus median AUC0.40.61.9-1.40.10.70.50.70.61.00.4
Reaction time num false alarms0.71.01.7-1.20.90.80.80.90.71.31.1
Reaction time num false alarms AUC0.60.92.0-0.70.90.80.60.51.31.40.8
Reaction time trials correct on left0.20.30.50.6-0.5-0.5-0.6-0.70.5-0.1-0.7
Reaction time trials on left0.10.20.30.4-0.4-0.4-0.5-0.50.5-0.0-0.5
Reaction time mean0.50.61.7-1.30.20.70.60.80.81.00.4
Reaction time mean AUC0.50.61.6-1.30.30.80.60.80.81.00.4
Median of all reaction times0.40.51.1-1.00.30.70.50.70.91.00.3
Reaction time omissions3.24.48.6-2.91.62.02.12.50.22.02.4
Reaction time false alarm rate0.60.91.6-0.81.10.90.70.70.91.31.0
Reaction time premature initiation rate0.20.20.50.00.70.50.40.5-0.20.50.6
Reaction time premature initiations0.00.10.20.20.30.20.10.10.10.40.3
Std. dev. reaction times0.10.21.1-1.0-0.40.2-0.00.30.20.4-0.1
Reaction time trials completed0.10.20.30.4-0.4-0.4-0.5-0.50.5-0.0-0.5
Reaction time trials AUC0.20.20.40.4-0.5-0.5-0.6-0.60.4-0.1-0.6
Social response proportion0.20.20.80.1-0.2-0.5-0.10.0-0.9-0.40.2
Social responses0.20.21.11.00.2-0.3-0.5-0.20.4-0.0-0.1
Social time0.40.50.91.0-0.6-0.8-0.5-0.8-0.7-0.8-0.5
Conditioned locomotion0.30.41.0-0.3-0.7-0.6-0.2-0.3-1.0-0.8-0.3
Cocaine response after cond. corrected0.80.91.8-1.1-1.4-0.8-0.5-0.1-1.3-1.2-0.5
Cocaine response after cond. not corrected0.40.51.8-1.3-0.9-0.20.30.3-0.9-0.6-0.1
Cocaine response before conditioning0.91.12.20.21.31.01.50.71.11.30.8
Saline control response1.21.63.10.3-1.7-1.5-0.7-0.7-1.7-1.5-1.1
Condit. Reinf. active minus inactive responses0.10.10.5-0.4-0.6-0.20.7-0.0-0.00.1-0.2
Condit. Reinf. active-inactive response ratio0.50.51.4-0.3-1.2-0.8-0.1-0.5-0.6-0.8-0.6
Condit. Reinf. active responses0.10.21.0-0.20.00.21.00.20.20.50.0
Condit. Reinf. inactive responses0.50.61.6-0.50.80.81.30.80.21.00.6
Condit. Reinf. lever presses1.92.74.1-0.61.81.81.91.22.02.01.2
Condit. Reinf. lever reinforcers received0.40.51.9-0.40.40.61.40.50.70.90.3
Pavlov. Cond. lever latency1.21.73.4-0.6-1.8-1.4-1.5-0.9-1.4-1.5-0.9
Pavlov. Cond. magazine entry latency0.70.82.00.41.41.11.30.8-0.10.60.9
Pavlov. Cond. change in total contacts1.11.63.50.21.51.31.10.91.91.60.7
Pavlov. Cond. index score1.82.34.60.42.11.71.81.21.31.61.2
Pavlov. Cond. latency score1.62.04.10.42.01.61.71.11.21.51.1
Pavlov. Cond. lever contacts1.31.83.40.61.81.41.40.91.71.60.9
Pavlov. Cond. magazine entry number1.01.32.9-0.3-1.7-1.3-1.4-1.0-0.5-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.10.20.50.2-0.7-0.5-0.2-0.5-0.2-0.2-0.6
Pavlov. Cond. lever-magazine prob. diff.1.62.14.20.42.01.61.81.21.21.51.1
Pavlov. Cond. response bias1.21.63.30.41.81.41.61.01.21.40.9
Conditioned reinforcement - actives0.50.50.70.6-0.7-0.7-0.6-0.8-0.5-0.7-0.8
Conditioned reinforcement - inactives1.11.22.21.2-1.1-1.3-1.2-1.5-0.1-0.6-1.2
Conditioned locomotion0.60.71.30.6-0.9-0.8-0.8-0.7-1.1-0.8-0.9
Intermittent access intake day 1-15 change1.21.22.41.4-0.8-1.0-1.5-1.4-0.1-0.4-1.2
Intermittent access intake escalation0.90.92.21.2-0.6-0.7-1.5-1.2-0.1-0.4-1.1
Intermittent access intake escalation 21.41.32.91.4-0.9-1.1-1.7-1.5-0.2-0.6-1.2
Intermitt. access day 1 inactive lever presses3.43.75.41.9-1.9-2.1-2.2-2.3-0.1-1.7-2.2
Intermitt. access day 15 inactive lever presses0.10.10.1-0.2-0.3-0.30.4-0.30.0-0.00.0
Intermitt. access escalation Index1.61.52.31.2-1.3-1.1-1.0-1.0-0.9-1.4-1.5
Intermittent access day 1 total infusions0.20.20.60.2-0.8-0.7-0.3-0.5-0.2-0.3-0.5
Intermittent access day 15 total infusions0.91.01.81.1-0.9-1.0-1.4-1.30.2-0.2-1.2
Intermittent access terminal intake (last 3 days)1.51.62.71.3-1.3-1.4-1.5-1.7-0.1-0.5-1.5
Intermittent access total infusions0.50.60.90.6-0.9-0.9-0.9-0.90.1-0.3-0.9
Intermittent access day 1 locomotion0.10.10.4-0.20.20.30.20.20.70.20.1
Intermittent access day 15 total locomotion0.30.30.60.4-0.6-0.4-0.8-0.6-0.3-0.5-0.8
Intermittent access total locomotion0.10.10.3-0.50.10.40.10.30.20.20.2
Intermittent access standard deviation4.64.98.32.4-2.2-2.6-2.6-2.9-0.3-1.2-2.4
Cocaine induced anxiety0.30.40.9-0.60.70.70.40.70.00.50.9
Post-drug Anxiety0.10.10.3-0.20.60.50.20.3-0.20.20.5
Baseline Anxiety0.20.20.60.5-0.4-0.3-0.4-0.5-0.0-0.4-0.8
Lifetime Intake0.80.91.50.7-1.2-1.2-1.0-1.1-0.1-0.6-1.1
Incentive Sensitization - Responses0.10.10.2-0.0-0.0-0.3-0.00.00.30.30.5
Incentive Sensitization - Breakpoint0.10.10.2-0.0-0.1-0.3-0.00.00.20.20.5
Progressive ratio test 1 active lever presses0.10.10.4-0.7-0.3-0.00.50.00.50.3-0.0
Progressive ratio test 1 breakpoint0.10.10.2-0.5-0.4-0.20.3-0.10.50.2-0.1
Progressive ratio test 1 inactive lever presses1.61.73.40.6-1.9-1.5-1.1-1.4-0.5-1.4-1.5
Progressive ratio test 2 active lever presses0.20.20.50.2-0.6-0.7-0.6-0.50.5-0.0-0.2
Progressive ratio test 2 breakpoint0.30.40.90.4-0.8-0.9-0.6-0.70.2-0.2-0.4
Progressive ratio test 2 inactive lever presses0.10.10.3-0.1-0.5-0.5-0.1-0.2-0.40.00.0
Total sessions with >9 infusions1.21.32.40.8-1.1-0.9-1.2-1.31.5-0.5-1.5
Short access day 1 total inactive lever presses1.01.12.20.7-1.2-1.1-0.6-1.0-1.1-1.5-0.9
Short access day 10 total inactive lever presses1.41.52.41.3-1.2-1.2-1.3-1.60.5-0.8-1.5
Short access day 1 total infusions3.13.36.71.1-2.6-2.3-1.5-2.00.0-1.5-2.1
Short access day 10 total infusions0.80.92.20.4-1.5-1.3-0.7-1.0-0.5-0.6-1.0
Short access total infusions0.70.81.80.4-1.4-1.2-0.6-1.00.0-0.6-1.0
Short access day 1 locomotion2.83.05.01.3-2.2-2.1-1.7-1.9-0.3-1.6-2.0
Short access day 10 total locomotion0.30.31.9-0.20.10.30.1-0.01.40.6-0.1
Short access total locomotion1.01.01.70.8-1.2-1.0-1.1-1.20.2-0.9-1.3
Compulsive drug intake1.61.62.61.6-1.1-1.4-1.3-1.3-0.6-1.4-1.3
One hour access (0.3 mA shock)0.91.12.21.5-0.7-1.2-1.3-1.3-0.4-0.4-0.9
One hour access (shock baseline)0.60.71.7-0.61.00.90.60.60.61.30.9
Number of responses in last shaping day0.80.83.7-0.20.50.60.7-0.11.91.20.2
Context. condit. distance diff. score0.20.21.2-1.1-0.50.0-0.10.3-0.2-0.4-0.0
Locomotion velocity, session 10.40.51.4-0.90.30.71.20.80.30.30.5
Locomotion distance, session 10.50.61.5-0.50.81.01.20.70.50.50.8
Locomotion velocity, session 20.20.30.50.7-0.5-0.3-0.2-0.70.0-0.5-0.7
Locomotion distance, session 20.00.10.2-0.00.20.30.40.1-0.2-0.30.3
Locomotion velocity, session 30.10.20.40.1-0.6-0.4-0.4-0.2-0.0-0.5-0.5
Locomotion distance, session 31.11.22.51.6-0.9-1.1-1.1-1.30.1-0.9-1.3
Stereotopy head waving bouts, day 30.20.31.00.5-0.1-0.3-0.6-0.51.00.4-0.4
Stereotopy head waving duration, day 30.30.32.0-0.20.10.20.00.01.40.80.1
Locomotion velocity, session 70.30.30.70.8-0.5-0.5-0.6-0.7-0.2-0.6-0.6
Locomotion distance, session 70.10.20.40.2-0.4-0.4-0.5-0.3-0.7-0.5-0.3
Stereotopy head waving bouts, day 71.41.67.42.7-0.0-1.0-1.2-1.40.2-0.4-0.9
Stereotopy head waving duration, day 70.91.24.82.2-0.2-0.9-1.1-1.20.3-0.4-0.8
Locomotion velocity, session 81.21.42.8-1.70.81.21.61.4-0.10.51.2
Locomotion distance, session 80.30.41.7-1.30.10.50.50.8-0.1-0.10.6
Degree of sensitization distance0.30.31.2-1.1-0.00.20.30.4-0.90.00.6
Degree of sensitization stereotypy0.91.04.92.20.0-0.7-0.8-1.1-0.0-0.4-0.7
Condit. Reinf. active minus inactive responses0.10.10.70.80.40.00.2-0.2-0.5-0.10.1
Condit. Reinf. active-inactive response ratio0.20.30.4-0.40.50.40.50.6-0.60.20.7
Condit. Reinf. active responses0.80.93.21.8-0.3-0.7-0.6-1.1-0.7-0.8-0.9
Condit. Reinf. inactive responses2.42.85.82.4-1.2-1.5-1.4-2.0-1.2-1.7-1.7
Incentive salience index mean0.40.52.11.50.1-0.3-0.3-0.6-0.8-0.5-0.4
Condit. Reinf. lever presses0.91.24.52.1-0.2-0.8-1.1-1.1-0.5-0.8-1.0
Time in familiar zone, hab. session 10.50.51.50.51.20.70.20.6-0.30.50.9
Time in novel zone, hab. session 10.50.52.2-0.3-0.7-0.4-0.3-0.51.50.2-0.6
Total zone transitions, hab. session 10.10.20.3-0.10.50.60.50.30.40.40.3
Total locomotion distance, hab. session 10.00.00.10.20.10.1-0.1-0.2-0.40.0-0.0
Locomotion velocity, hab. session 10.10.10.60.5-0.1-0.1-0.2-0.3-0.8-0.4-0.2
Time in familiar zone, hab. session 20.20.21.20.50.1-0.2-0.1-0.1-1.1-0.40.1
Time in novel zone, hab. session 20.30.30.6-0.70.40.60.40.50.80.50.2
Total zone transitions, hab. session 20.10.10.60.10.30.40.70.20.40.20.1
Total locomotion distance, hab. session 20.20.31.0-0.40.20.40.70.5-1.0-0.10.5
Locomotion velocity, hab. session 20.20.30.8-0.30.30.40.70.4-0.9-0.10.5
Novel to familiar place preference ratio0.40.51.0-1.00.50.50.20.80.70.60.7
Novelty place preference0.50.50.9-0.90.60.70.40.90.60.60.8
Time in novel zone, NPP test0.30.30.5-0.60.60.60.20.60.70.60.6
Total zone transitions, NPP test0.40.51.00.9-0.7-0.6-0.3-0.7-0.7-1.0-0.8
Total locomotion distance, NPP test1.11.52.21.1-1.5-1.2-1.1-1.4-0.6-1.2-1.4
Locomotion velocity, NPP test1.11.62.60.9-1.6-1.3-1.0-1.3-1.0-1.4-1.4
Pavlov. Cond. lever latency0.10.10.4-0.7-0.10.10.20.50.30.20.2
Pavlov. Cond. magazine entry latency0.81.11.9-0.11.41.11.30.50.91.31.1
Pavlov. Cond. change in total contacts0.10.10.30.10.60.40.50.2-0.30.20.3
Pavlov. Cond. index score0.20.20.50.10.60.60.7-0.00.50.60.3
Pavlov. Cond. latency score0.20.20.50.10.60.50.7-0.00.30.50.3
Pavlov. Cond. lever contacts0.10.10.20.50.1-0.00.1-0.5-0.2-0.1-0.2
Pavlov. Cond. magazine entry number0.80.91.6-0.0-1.3-1.1-1.3-0.4-1.0-1.1-0.9
Pavlov. Cond. intertrial magazine entries1.21.43.90.7-1.1-1.1-0.8-1.0-2.0-1.4-0.9
Pavlov. Cond. lever-magazine prob. diff.0.30.40.8-0.30.60.70.90.20.50.60.5
Pavlov. Cond. response bias0.20.20.50.60.70.40.5-0.20.40.40.2
Bone: apparent density1.22.03.51.2-1.3-1.5-1.5-1.2-1.2-1.9-1.4
Bone surface1.32.23.41.2-1.6-1.6-1.5-1.3-1.3-1.8-1.5
Bone volume2.84.76.81.6-2.3-2.4-2.2-2.0-1.9-2.6-2.2
Bone: connectivity density0.30.50.90.8-0.5-0.7-0.9-0.6-0.3-1.0-0.6
Bone: cortical apparent density0.10.10.40.10.50.3-0.10.20.60.30.3
Bone: cortical area0.50.72.2-0.3-1.1-0.7-0.2-0.4-1.5-1.2-0.6
Bone: cortical porosity0.10.10.8-0.4-0.10.10.90.3-0.40.10.2
Bone: cortical porosity0.30.31.30.1-0.5-0.30.4-0.2-1.1-0.6-0.3
Bone: cortical thickness0.81.32.0-1.21.11.31.41.10.31.01.2
Bone: cortical thickness0.40.50.8-0.60.70.90.80.70.40.60.6
Bone: cortical tissue density0.00.10.20.30.30.1-0.3-0.00.50.10.1
Bone: elastic displacement0.00.10.20.4-0.0-0.20.0-0.40.00.0-0.0
Bone: elastic work0.00.00.0-0.00.20.20.2-0.2-0.20.00.1
Bone: endosteal estimation1.32.94.31.2-1.9-1.7-1.3-1.5-2.1-2.0-1.7
Bone: endosteal perimeter2.96.010.60.3-3.3-2.6-1.7-1.7-3.1-3.2-2.2
Bone: final force0.10.20.7-0.50.20.40.50.5-0.8-0.20.3
Bone: final moment0.10.10.8-0.20.00.20.40.2-0.9-0.30.1
Bone: marrow area1.22.74.01.2-1.8-1.6-1.2-1.5-2.0-2.0-1.6
Bone: maximum diameter1.62.95.10.2-2.3-1.9-1.3-1.4-2.0-2.2-1.5
Bone: maximum force0.20.31.3-0.3-0.5-0.10.0-0.0-1.2-0.8-0.2
Bone: maximum moment0.20.41.5-0.0-0.6-0.4-0.1-0.3-1.2-0.9-0.5
Bone: minimum diameter2.03.77.70.7-2.1-1.8-1.5-1.4-2.8-2.6-1.6
Bone: periosteal estimation1.53.05.50.9-2.0-1.7-1.2-1.4-2.4-2.2-1.6
Bone: periosteal perimeter1.83.05.60.0-2.4-1.8-1.2-1.1-2.2-2.4-1.6
Bone: post-yield work1.52.13.41.0-1.4-1.5-1.6-1.0-1.6-1.8-1.2
Bone: stiffness0.81.23.0-1.70.51.11.21.4-1.10.10.9
Bone: tissue strength0.00.00.10.20.20.20.20.0-0.2-0.20.1
Bone: trabecular number0.81.32.11.3-0.9-1.1-1.5-1.2-0.3-1.3-1.2
Bone: trabecular spacing0.20.20.7-0.70.10.40.80.30.50.50.2
Bone: trabecular thickness1.11.32.30.5-1.1-1.1-1.4-0.8-1.4-1.5-0.9
Bone: trabecular tissue density1.41.93.3-1.71.21.81.51.40.61.11.2
Breakpoint value in progressive ratio session3.43.85.9-2.02.12.32.02.4-0.60.92.4
Distance traveled before self-admin0.50.61.1-0.60.70.70.60.70.81.00.7
Distance traveled after self-admin0.70.80.90.6-1.0-1.0-0.9-0.8-1.0-0.8-0.8
Delta time in closed arm before/after self-admin0.10.10.20.4-0.1-0.5-0.1-0.3-0.4-0.3-0.2
Delta time in open arm before/after self-admin1.00.91.5-1.20.81.21.01.1-0.40.60.9
Diff in mean of infusions in LGA sessions1.51.72.8-1.71.01.41.51.5-0.30.81.7
Extinction: sum of active levers before priming1.11.13.30.61.51.10.30.31.81.30.4
Active lever presses in extinction session 63.02.95.8-1.41.72.00.91.32.41.91.5
Delta distance traveled before/after self-admin0.60.61.00.3-1.0-0.9-0.7-0.7-0.9-1.0-0.7
Delta ambulatory time before/after self-admin1.31.42.80.8-1.2-1.2-1.1-1.0-1.3-1.7-1.0
Time in closed arm before self-admin0.70.81.81.0-0.7-0.8-1.4-0.90.3-0.6-1.0
Time in closed arm after self-admin0.20.20.60.8-0.1-0.5-0.4-0.4-0.2-0.3-0.2
Time in open arm before self-admin0.30.30.5-0.60.50.50.70.50.40.30.7
Time in open arm after self-admin1.82.03.1-1.51.51.81.61.40.81.21.4
Sum of active levers in priming session hrs 5-63.73.76.7-1.22.62.21.92.10.21.62.4
Time to tail flick, vehicle, before self-admin1.41.42.61.1-1.4-1.1-1.1-1.50.5-0.8-1.6
Time to tail flick, vehicle, after self-admin0.20.21.1-0.1-0.4-0.2-0.30.2-1.0-0.60.0
Time to tail flick, test, before self-admin0.20.21.5-0.2-0.1-0.30.10.2-1.2-0.10.4
Time to tail flick, test, after self-admin0.40.41.70.2-0.1-0.2-0.20.0-1.3-1.1-0.0
Delta time to tail flick, vehicle, before/after SA0.70.62.4-0.70.30.20.50.9-1.6-0.21.0
Delta time to tail flick, test, before/after SA0.20.20.90.4-0.3-0.2-0.4-0.3-0.2-0.9-0.6
Ambulatory time before self-admin1.11.11.8-1.00.91.20.91.01.21.31.0
Ambulatory time after self-admin0.30.31.20.2-0.5-0.5-0.6-0.3-1.1-0.7-0.3
Total heroin consumption2.02.43.5-1.71.51.81.61.90.51.01.9
Area under the delay curve0.10.10.30.20.0-0.1-0.6-0.30.20.0-0.1
Delay disc. indifference point, 0s delay0.60.61.2-1.10.50.70.60.90.50.81.0
Delay disc. indifference point, 16s delay0.60.60.9-1.00.80.60.70.70.20.91.0
Delay disc. indifference point, 2s delay0.10.10.30.10.20.1-0.3-0.20.50.50.1
Delay disc. indifference point, 24s delay0.20.20.60.3-0.4-0.5-0.7-0.6-0.2-0.3-0.4
Delay disc. indifference point, 4s delay0.60.71.20.3-1.0-0.8-1.1-0.8-0.2-0.8-1.0
Delay disc. indifference point, 8s delay0.30.31.00.6-0.3-0.4-1.0-0.70.2-0.1-0.6
Delay discount exponential model param0.20.20.6-0.40.20.20.80.5-0.10.20.4
Delay discount hyperbolic model param0.20.20.7-0.40.20.20.80.6-0.20.10.4
Fecal boli incidents, locomotor time 10.30.41.01.0-0.5-0.4-0.6-0.5-0.2-0.3-0.9
Change in fecal boli incidents, locomotor task1.11.01.60.4-1.2-1.2-1.2-1.0-0.8-1.2-0.7
Time >=10cm from walls, locomotor time 13.03.16.42.5-1.3-1.8-1.5-1.9-1.0-1.6-1.9
Bouts of movement, locomotor time 11.92.15.1-1.41.31.31.11.11.62.31.3
Total resting periods, locomotor time 11.41.64.4-0.91.21.20.80.71.62.10.9
Rest time, locomotor task time 13.13.45.82.3-1.7-1.8-1.9-2.4-0.2-1.1-2.4
Distance moved, locomotor task time 11.61.82.9-1.41.31.31.71.7-0.50.51.7
Vertical activity count, locomotor time 11.21.26.5-0.9-0.2-0.20.50.9-2.6-0.80.8
Time >=10cm from walls, locomotor time 20.40.40.8-0.90.30.40.80.6-0.90.00.5
Bouts of movement, locomotor time 20.70.73.00.10.70.70.10.11.71.3-0.1
Total resting periods, locomotor time 20.50.62.30.50.50.4-0.3-0.31.51.1-0.4
Rest time, locomotor task time 21.41.62.91.7-1.0-1.2-1.5-1.70.0-0.7-1.5
Distance moved, locomotor task time 21.61.93.3-1.81.11.31.81.6-0.10.91.5
Vertical activity count, locomotor time 21.31.54.4-1.7-0.10.31.21.4-2.1-0.41.0
Weight adjusted by age0.30.40.8-0.50.50.60.40.30.70.90.7
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.0-0.3-0.2-0.5-0.30.3-0.1-0.3
Locomotion in novel chamber2.02.53.6-1.51.71.91.81.60.41.41.8
Locomotion in novel chamber post-restriction0.70.91.9-1.40.50.70.91.11.00.61.0
Progressive ratio0.40.51.0-0.30.80.80.50.70.61.00.7
Food seeking constrained by brief footshock1.72.04.01.3-1.6-1.3-1.3-1.7-0.2-1.3-2.0
Seeking ratio, punishment vs. effort1.31.52.50.9-1.4-1.3-1.0-1.4-0.6-1.4-1.6
Run reversals in cocaine runway, females1.31.32.70.3-1.5-1.3-0.5-0.9-1.7-1.2-1.0
Run reversals in cocaine runway, males0.80.81.51.1-0.3-0.6-1.2-1.11.1-0.3-0.8
Latency to leave start box in cocaine runway0.91.02.2-1.50.60.91.11.20.20.71.0
Latency to leave start box in cocaine runway, F2.12.35.0-2.21.01.51.41.60.91.41.6
Latency to leave start box in cocaine runway, M0.30.31.70.10.0-0.00.40.3-1.3-0.50.0
Cd content in liver0.30.40.80.9-0.6-0.50.1-0.70.70.1-0.8
Co content in liver0.30.42.11.50.5-0.2-0.5-0.4-0.0-0.0-0.2
Cu content in liver0.20.30.6-0.70.40.60.50.80.10.40.5
Fe content in liver0.40.40.90.3-0.7-0.8-0.9-0.6-0.5-0.5-0.7
K content in liver0.60.61.4-0.0-1.2-0.7-0.5-0.6-0.7-1.1-0.9
Mg content in liver1.01.12.2-0.3-1.5-1.0-1.0-0.7-0.8-1.4-1.1
Mn content in liver1.01.12.2-0.4-1.4-0.9-1.1-0.5-1.3-1.5-0.8
Na content in liver0.10.10.6-0.5-0.10.20.70.2-0.1-0.10.1
Rb content in liver0.00.00.0-0.10.0-0.1-0.00.1-0.2-0.10.0
Se content in liver0.40.51.5-1.20.20.50.20.9-0.9-0.10.6
Sr content in liver0.10.10.30.6-0.2-0.30.1-0.5-0.3-0.2-0.3
Zn content in liver0.30.41.30.5-0.4-0.6-0.3-0.4-1.1-0.8-0.5