Camkk1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000018242 0.14 0.09 9.3e-04 0.01 0.03 0.03 0.03 1.4e-01 8.3e-03 8.3e-03 1.0e-02
2 BLA intron excision ratio chr10:57645314:57645696 0.09 0.07 1.7e-03 0.04 0.03 0.06 0.03 3.8e-03 6.0e-03 6.6e-04 1.7e-02
3 BLA intron excision ratio chr10:57645749:57646107 0.08 0.08 9.3e-03 0.01 0.01 0 0.01 1.2e-01 6.4e-02 1.9e-01 1.3e-01
4 Brain gene expression ENSRNOG00000018242 0.35 0.11 0.0e+00 0.3 0.34 0.34 0.34 5.9e-28 2.9e-32 9.7e-33 5.8e-33
5 Brain isoform ratio ENSRNOT00000104077 0.1 0.06 7.4e-10 0.1 0.1 0.09 0.09 2.6e-09 3.9e-09 2.3e-08 6.4e-09
6 Brain intron excision ratio chr10:57637483:57644236 0.04 0.03 9.0e-04 0.03 0.04 0.04 0.04 1.9e-03 1.8e-04 1.7e-04 2.4e-04
7 IL gene expression ENSRNOG00000018242 0.25 0.15 7.5e-03 0.06 -0.01 0.03 -0 1.3e-02 5.3e-01 6.5e-02 3.7e-01
8 LHb intron excision ratio chr10:57644145:57644236 0.19 0.13 5.8e-03 0.06 0.06 0.03 0.12 1.3e-02 1.8e-02 6.9e-02 9.2e-04
9 NAcc gene expression ENSRNOG00000018242 0.09 0.06 2.8e-04 0.05 0.04 0.04 0.04 1.4e-04 7.1e-04 4.0e-04 2.8e-04
10 NAcc intron excision ratio chr10:57644145:57644236 0.14 0.13 6.3e-03 0.01 0.02 0.02 0.01 5.5e-02 1.4e-02 6.4e-03 4.4e-02
11 OFC gene expression ENSRNOG00000018242 0.43 0.16 1.8e-05 0.13 0.14 0.11 0.13 5.9e-04 3.9e-04 1.3e-03 5.5e-04
12 PL gene expression ENSRNOG00000018242 0.37 0.15 0.0e+00 0.13 0.21 0.23 0.24 5.3e-10 3.7e-16 2.5e-17 4.7e-18
13 PL intron excision ratio chr10:57644145:57644236 0.11 0.06 7.6e-08 0.11 0.09 0.1 0.09 8.5e-09 2.2e-07 1.0e-07 1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.20.71.2-1.0-0.91.1-0.8-0.5-0.5-0.90.8-0.7-0.1-0.8-0.91.0
BMI without tail0.51.01.7-1.3-0.70.8-1.2-0.6-1.0-1.3-0.3-1.11.1-1.2-1.31.1
Body weight0.94.09.5-2.7-1.10.6-3.00.6-0.7-1.6-1.3-3.10.7-3.0-2.61.6
Epididymis fat weight3.37.712.2-3.5-2.13.4-2.9-1.8-2.7-3.41.7-2.51.0-2.8-3.43.5
Glucose1.32.04.91.81.4-0.52.2-0.9-0.30.90.62.21.22.21.6-0.9
Heart weight0.91.32.5-1.3-0.91.4-0.9-1.0-1.1-1.40.9-0.80.6-0.9-1.41.6
Left kidney weight0.30.86.0-0.00.60.00.4-0.9-1.1-0.5-0.60.52.40.3-0.30.6
Right kidney weight0.20.53.5-0.10.6-0.10.3-0.7-0.9-0.3-0.60.31.90.2-0.30.5
Tail length2.06.212.7-3.2-0.30.4-3.60.5-1.9-2.2-2.5-3.42.4-3.5-3.12.0
Length with tail1.13.99.1-2.5-0.4-0.0-3.01.1-0.8-1.3-2.2-3.01.2-2.9-2.61.2
Length without tail0.81.73.9-1.8-1.00.7-1.90.6-0.3-0.9-0.3-2.0-0.2-1.9-1.71.1
Liver weight, left0.40.71.8-0.9-0.1-0.5-1.10.80.1-0.1-1.4-1.30.5-1.2-0.80.2
Liver weight, right1.01.73.2-1.6-0.20.5-1.5-0.3-1.3-1.3-0.9-1.51.8-1.5-1.71.3
Parametrial fat weight9.518.529.2-5.4-3.24.9-4.6-2.7-4.3-5.31.9-3.82.8-4.5-5.45.3
Retroperitoneal fat weight0.10.51.70.20.11.00.4-1.0-0.8-0.61.30.70.20.40.10.6
Intraocular pressure1.31.88.50.2-0.52.01.0-1.9-1.2-0.92.91.50.01.10.40.8
Extensor digitorum longus weight2.510.223.2-3.1-2.84.8-2.1-3.4-3.4-4.23.9-1.30.9-1.9-3.14.2
Soleus weight2.57.213.5-3.7-1.62.1-3.6-0.4-2.0-3.0-0.3-3.41.2-3.6-3.63.0
Tibialis anterior weight2.99.917.7-3.7-2.44.2-3.1-2.3-3.0-4.12.7-2.40.5-2.9-3.54.1
Tibia length0.71.98.5-0.80.7-1.6-1.42.00.50.5-2.9-1.70.5-1.5-0.7-0.4
Number of licking bursts0.20.20.40.60.5-0.50.40.30.40.6-0.20.3-0.20.50.6-0.6
Food consumed during 24 hour testing period0.30.41.10.00.1-0.7-0.31.00.90.7-0.7-0.6-0.8-0.40.3-0.7
Times rat made contact with spout0.80.92.10.60.9-1.50.11.30.91.2-1.4-0.2-0.20.10.9-1.2
Mean time between licks in bursts1.41.94.0-1.7-0.91.2-1.4-0.7-1.4-1.7-0.0-1.21.4-1.4-2.01.7
Mean num. licks in bursts0.10.10.5-0.20.1-0.3-0.40.40.10.1-0.7-0.40.3-0.4-0.2-0.0
Std. dev. time between licks in bursts0.40.50.8-0.9-0.60.6-0.7-0.5-0.6-0.9-0.1-0.60.8-0.7-0.90.9
Water consumed over 24 hours2.22.66.60.71.1-2.3-0.22.61.92.0-2.1-0.8-1.4-0.21.1-2.0
Indifference point 0 sec0.91.43.80.40.8-1.9-0.21.91.31.5-1.9-0.6-0.5-0.20.6-1.4
Indifference point AUC1.21.44.6-0.1-0.41.40.8-2.1-1.4-1.11.51.11.60.8-0.31.1
Indifference point function ln k3.65.112.41.10.9-3.1-0.13.53.02.7-2.7-0.9-2.6-0.31.7-2.8
Indifference point function log k3.65.112.41.10.9-3.1-0.13.53.02.7-2.7-0.9-2.6-0.31.7-2.8
Delay discounting total patch changes 0 sec0.61.03.00.30.8-1.6-0.11.50.91.2-1.7-0.5-0.2-0.10.4-1.1
Delay discounting total patch changes 12 sec0.81.03.1-0.70.01.0-0.2-1.4-1.5-1.10.50.01.8-0.1-1.01.2
Delay discounting total patch changes 18 sec0.40.62.5-0.5-0.10.6-0.2-1.0-1.1-0.90.10.11.6-0.1-0.80.9
Delay discounting total patch changes 24 sec0.40.51.9-0.00.30.50.5-1.1-1.0-0.40.40.51.40.5-0.10.5
Delay discounting total patch changes 6 sec0.81.23.6-0.3-0.31.20.4-1.9-1.5-1.11.10.61.70.5-0.71.2
Delay discounting time to switch 0 sec1.01.53.0-1.1-0.51.4-0.8-1.4-1.7-1.70.5-0.41.3-0.8-1.61.7
Delay discounting water rate 0 sec0.61.01.91.20.6-1.20.90.81.21.3-0.50.7-0.50.91.2-1.4
Delay discounting water rate 12 sec0.20.30.5-0.7-0.50.4-0.7-0.1-0.3-0.7-0.2-0.60.4-0.7-0.60.7
Delay discounting water rate 18 sec0.50.62.0-0.50.3-0.4-0.91.40.60.4-0.5-1.1-1.3-0.9-0.0-0.3
Delay discounting water rate 24 sec0.00.00.10.20.1-0.00.2-0.10.00.00.10.30.20.30.1-0.1
Delay discounting water rate 6 sec0.30.51.00.80.4-0.80.70.40.70.8-0.30.5-0.40.71.0-1.0
Locomotor activity0.40.71.4-0.90.00.9-0.6-0.9-1.2-1.10.4-0.40.9-0.5-0.81.1
Locomotor testing distance1.93.17.1-1.3-0.22.0-0.5-2.5-2.7-2.41.10.02.7-0.4-1.52.3
Locomotor testing rearing2.33.67.9-1.1-0.52.6-0.1-2.8-2.8-2.42.10.52.1-0.1-1.42.4
Light reinforcement 10.91.63.6-1.1-0.71.9-0.4-1.6-1.7-1.61.6-0.00.9-0.4-1.21.7
Light reinforcement 20.10.10.40.0-0.30.40.3-0.6-0.2-0.30.40.40.40.30.20.3
Reaction time number correct0.10.20.6-0.2-0.8-0.2-0.50.30.6-0.1-0.4-0.5-0.5-0.5-0.00.0
Reaction time mean minus median0.60.81.71.10.4-0.41.10.30.81.00.51.1-1.31.01.1-0.9
Reaction time mean minus median AUC0.40.52.60.5-0.20.30.60.00.50.41.20.6-1.60.50.4-0.3
Reaction time num false alarms1.01.42.91.30.2-0.81.00.91.51.30.31.0-1.71.11.6-1.4
Reaction time num false alarms AUC0.91.22.41.30.2-0.71.10.71.31.20.41.0-1.61.11.5-1.3
Reaction time trials correct on left0.10.20.6-0.2-0.8-0.2-0.50.30.6-0.1-0.4-0.5-0.5-0.5-0.00.0
Reaction time trials on left0.10.20.6-0.2-0.8-0.1-0.40.30.6-0.1-0.3-0.5-0.6-0.4-0.00.0
Reaction time mean0.20.30.60.70.5-0.30.60.30.40.60.30.7-0.80.50.8-0.5
Reaction time mean AUC0.50.71.41.10.7-0.51.10.30.60.90.31.0-0.90.91.2-0.9
Median of all reaction times0.10.10.30.50.5-0.10.50.00.10.30.30.6-0.40.40.6-0.3
Reaction time omissions0.30.52.0-0.3-0.51.20.1-0.8-0.6-0.61.40.2-0.40.0-0.40.7
Reaction time false alarm rate0.60.91.61.10.5-0.51.00.60.91.10.41.0-1.01.11.2-1.1
Reaction time premature initiation rate1.21.64.30.40.1-1.5-0.41.91.81.3-1.3-0.8-2.1-0.40.7-1.3
Reaction time premature initiations1.11.65.20.2-0.4-1.4-0.61.92.01.1-1.3-1.0-2.3-0.60.6-1.1
Std. dev. reaction times1.11.53.01.40.7-0.91.30.81.31.50.21.1-1.71.11.5-1.4
Reaction time trials completed0.10.20.6-0.2-0.8-0.1-0.40.30.6-0.1-0.3-0.5-0.6-0.4-0.00.0
Reaction time trials AUC0.10.20.7-0.2-0.8-0.1-0.40.30.6-0.1-0.3-0.5-0.7-0.40.00.0
Social response proportion2.02.16.3-1.30.1-1.0-2.12.10.70.3-2.0-2.5-0.8-2.0-0.8-0.5
Social responses2.02.55.1-2.2-1.01.3-2.0-0.4-1.4-1.7-0.1-1.91.4-1.9-1.91.8
Social time1.21.52.9-1.7-0.80.9-1.7-0.0-0.9-1.2-0.2-1.60.7-1.7-1.51.3
Conditioned locomotion0.80.91.91.40.9-0.91.30.30.61.1-0.01.2-0.21.21.0-1.1
Cocaine response after cond. corrected0.40.51.4-0.3-0.1-0.7-0.61.20.80.6-0.7-0.9-0.9-0.60.1-0.6
Cocaine response after cond. not corrected0.30.40.9-0.5-0.4-0.3-0.70.90.60.2-0.5-0.9-0.9-0.7-0.3-0.2
Cocaine response before conditioning0.50.71.3-0.8-0.81.0-0.6-0.9-0.8-1.20.6-0.40.2-0.6-0.91.1
Saline control response0.40.51.2-0.8-0.00.8-0.6-0.7-1.1-1.00.3-0.50.7-0.5-0.70.9
Condit. Reinf. active minus inactive responses0.40.61.8-0.10.3-0.8-0.51.10.80.6-0.8-0.8-1.3-0.40.3-0.7
Condit. Reinf. active-inactive response ratio0.60.61.30.20.8-1.1-0.11.20.80.9-1.0-0.4-0.9-0.10.4-0.9
Condit. Reinf. active responses0.20.31.2-0.20.3-0.4-0.40.80.50.4-0.4-0.6-1.1-0.40.3-0.5
Condit. Reinf. inactive responses0.10.20.80.0-0.20.60.2-0.5-0.2-0.20.90.2-0.30.20.30.2
Condit. Reinf. lever presses0.40.61.40.91.0-0.61.0-0.00.20.70.10.9-0.51.01.2-0.8
Condit. Reinf. lever reinforcers received0.20.31.7-0.10.2-0.3-0.20.60.50.4-0.1-0.4-1.3-0.20.5-0.5
Pavlov. Cond. lever latency1.52.14.2-1.7-1.31.6-1.6-0.6-1.1-1.70.7-1.30.6-1.6-2.11.8
Pavlov. Cond. magazine entry latency0.91.02.41.01.1-1.60.70.80.91.2-1.30.5-0.30.70.8-1.3
Pavlov. Cond. change in total contacts0.71.02.01.01.3-1.40.90.70.61.2-1.10.7-0.10.81.1-1.2
Pavlov. Cond. index score1.21.62.71.61.4-1.31.60.20.61.3-0.61.5-0.11.61.6-1.4
Pavlov. Cond. latency score1.51.93.51.81.5-1.41.90.00.61.4-0.51.8-0.11.81.7-1.5
Pavlov. Cond. lever contacts0.70.92.11.11.4-1.21.10.20.21.0-0.80.90.31.11.2-1.0
Pavlov. Cond. magazine entry number0.70.91.5-1.1-1.11.2-1.0-0.4-0.6-1.00.8-0.90.1-1.0-1.01.1
Pavlov. Cond. intertrial magazine entries0.71.01.7-1.2-0.71.3-1.0-0.7-1.0-1.30.8-0.90.2-1.0-0.81.2
Pavlov. Cond. lever-magazine prob. diff.1.31.62.71.61.5-1.41.60.20.61.3-0.61.5-0.11.61.6-1.4
Pavlov. Cond. response bias0.91.22.11.21.4-1.41.10.50.61.2-1.00.90.01.11.4-1.3
Conditioned reinforcement - actives0.90.93.1-0.8-0.71.6-0.5-0.9-0.8-1.01.7-0.3-0.7-0.4-1.01.0
Conditioned reinforcement - inactives1.41.63.8-1.0-1.01.9-0.6-1.7-1.2-1.71.9-0.30.4-0.5-1.21.5
Conditioned locomotion0.40.51.80.10.60.60.6-1.3-1.0-0.60.90.60.40.6-0.10.4
Intermittent access intake day 1-15 change1.21.23.30.80.31.21.2-1.8-0.9-0.61.81.60.41.40.30.4
Intermittent access intake escalation1.51.53.91.10.70.91.6-1.7-0.9-0.31.62.00.71.70.60.2
Intermittent access intake escalation 21.91.95.51.71.7-0.12.1-0.9-0.50.60.92.30.72.01.5-0.6
Intermitt. access day 1 inactive lever presses0.60.61.51.20.2-0.31.2-0.50.60.40.61.2-0.31.20.9-0.5
Intermitt. access day 15 inactive lever presses0.20.20.50.50.5-0.60.00.50.40.3-0.70.20.20.00.3-0.4
Intermitt. access escalation Index1.71.63.4-1.7-1.40.3-1.80.3-0.2-1.0-0.9-1.80.6-1.8-1.50.9
Intermittent access day 1 total infusions1.82.04.5-1.6-1.12.1-1.0-1.5-1.5-1.71.8-0.70.0-0.9-1.61.7
Intermittent access day 15 total infusions3.33.610.4-0.7-0.93.00.3-3.1-2.3-2.23.20.90.80.5-1.22.0
Intermittent access terminal intake (last 3 days)3.03.37.9-1.4-0.62.8-0.7-2.3-2.5-2.32.5-0.10.9-0.5-1.72.1
Intermittent access total infusions1.81.94.9-0.9-0.52.2-0.2-2.1-1.8-1.72.20.20.4-0.1-1.21.5
Intermittent access day 1 locomotion1.31.33.2-0.9-1.31.4-0.5-1.8-1.1-1.61.0-0.30.7-0.4-1.21.3
Intermittent access day 15 total locomotion1.11.13.30.1-0.21.30.6-1.8-1.4-1.01.61.01.10.7-0.31.0
Intermittent access total locomotion0.40.51.9-0.3-0.60.8-0.0-1.4-0.8-1.00.70.10.50.1-0.70.7
Intermittent access standard deviation3.23.411.90.6-0.02.51.5-3.0-1.8-1.43.42.10.71.6-0.01.3
Cocaine induced anxiety1.92.24.21.71.0-1.71.11.21.91.5-0.80.9-1.91.01.4-2.0
Post-drug Anxiety0.50.61.80.6-0.1-0.90.21.11.30.9-0.60.1-1.00.20.6-1.0
Baseline Anxiety1.01.02.1-1.1-1.11.4-0.6-0.6-1.1-0.90.9-0.51.4-0.6-0.81.4
Lifetime Intake2.73.07.5-1.2-0.82.7-0.4-2.5-2.2-2.22.70.10.4-0.2-1.51.9
Incentive Sensitization - Responses0.20.20.7-0.5-0.80.5-0.4-0.20.1-0.30.6-0.5-0.7-0.4-0.30.4
Incentive Sensitization - Breakpoint0.20.20.6-0.4-0.70.5-0.3-0.20.1-0.30.6-0.4-0.5-0.3-0.20.3
Progressive ratio test 1 active lever presses1.51.53.0-1.4-0.91.7-1.1-1.0-1.2-1.51.4-1.0-0.0-1.0-1.51.4
Progressive ratio test 1 breakpoint2.32.33.9-1.9-1.22.0-1.6-0.9-1.4-1.81.4-1.40.0-1.5-2.01.7
Progressive ratio test 1 inactive lever presses0.80.82.7-0.5-0.21.2-0.0-1.6-1.2-1.21.20.10.80.1-0.81.0
Progressive ratio test 2 active lever presses0.90.92.4-1.0-0.81.5-0.7-0.8-0.9-1.01.5-0.6-0.3-0.6-0.91.1
Progressive ratio test 2 breakpoint0.50.61.8-0.8-0.61.2-0.5-0.6-0.5-0.71.3-0.5-0.5-0.5-0.70.7
Progressive ratio test 2 inactive lever presses1.31.63.7-0.9-0.71.9-0.4-1.8-1.5-1.61.9-0.10.7-0.3-1.01.4
Total sessions with >9 infusions2.12.34.8-1.4-0.12.2-0.8-2.0-2.2-2.01.8-0.60.5-0.7-1.71.7
Short access day 1 total inactive lever presses0.30.31.7-0.4-1.30.4-0.4-0.70.3-0.70.4-0.4-0.2-0.3-0.60.4
Short access day 10 total inactive lever presses0.30.31.20.2-0.6-0.80.00.51.10.4-0.8-0.3-0.0-0.00.3-0.4
Short access day 1 total infusions2.62.78.8-0.4-1.22.50.4-2.8-1.7-1.83.00.80.30.5-0.91.6
Short access day 10 total infusions1.61.75.8-1.0-0.72.2-0.5-1.4-1.3-1.52.4-0.2-0.6-0.4-1.21.4
Short access total infusions3.03.39.0-0.9-0.72.9-0.1-2.8-2.3-2.23.00.50.50.1-1.42.0
Short access day 1 locomotion1.01.04.50.1-0.31.50.6-1.7-0.9-0.82.10.8-0.10.7-0.20.8
Short access day 10 total locomotion0.30.31.90.0-0.70.60.4-1.4-0.4-0.70.70.40.10.4-0.30.4
Short access total locomotion0.40.42.00.0-0.40.80.3-1.4-0.6-0.81.00.40.00.4-0.40.5
Compulsive drug intake1.01.03.3-0.10.3-1.5-0.61.41.20.7-1.8-1.0-0.3-0.60.1-1.2
One hour access (0.3 mA shock)1.41.76.1-1.0-0.62.1-0.4-1.5-1.4-1.42.5-0.2-0.5-0.3-1.11.3
One hour access (shock baseline)1.92.17.0-0.9-1.12.4-0.1-2.0-1.6-1.62.60.20.1-0.0-1.01.7
Number of responses in last shaping day0.80.82.00.7-0.60.71.2-1.4-0.0-0.11.41.2-0.01.30.5-0.0
Context. condit. distance diff. score1.31.63.6-1.4-1.91.5-1.3-0.5-0.3-1.31.1-1.2-0.6-1.3-1.71.3
Locomotion velocity, session 12.52.75.1-2.3-0.41.1-2.2-0.2-1.6-1.8-0.4-2.11.0-2.2-2.21.8
Locomotion distance, session 10.81.02.3-1.1-0.01.0-0.8-1.0-1.5-1.30.3-0.51.3-0.7-1.21.3
Locomotion velocity, session 20.50.63.3-0.40.5-1.1-0.71.00.30.2-1.8-0.80.4-0.7-0.2-0.3
Locomotion distance, session 20.30.51.0-0.9-0.30.2-1.00.1-0.4-0.6-0.5-1.00.3-1.0-1.00.6
Locomotion velocity, session 31.92.24.81.71.4-2.21.41.01.21.8-1.71.20.41.41.4-1.9
Locomotion distance, session 30.20.20.70.4-0.4-0.30.20.30.70.40.00.1-0.80.20.2-0.5
Stereotopy head waving bouts, day 30.20.20.80.00.3-0.5-0.10.2-0.00.1-0.9-0.20.8-0.1-0.6-0.1
Stereotopy head waving duration, day 30.60.71.80.90.4-0.11.2-1.1-0.50.00.01.31.41.20.2-0.1
Locomotion velocity, session 70.10.10.4-0.1-0.60.50.0-0.30.1-0.20.70.1-0.60.0-0.30.2
Locomotion distance, session 70.30.42.6-0.0-0.80.4-0.10.20.70.10.8-0.1-1.6-0.1-0.3-0.1
Stereotopy head waving bouts, day 70.80.91.8-1.1-0.70.7-0.9-0.7-1.0-1.3-0.3-0.71.3-0.9-1.11.3
Stereotopy head waving duration, day 71.01.22.2-1.3-0.90.9-1.1-0.8-1.0-1.4-0.2-0.91.3-1.1-1.31.5
Locomotion velocity, session 80.80.91.7-1.1-0.91.2-0.8-0.8-1.0-1.20.6-0.60.7-0.8-1.31.2
Locomotion distance, session 81.72.55.0-2.1-1.81.4-2.1-0.2-0.7-1.70.3-1.90.1-2.0-2.21.6
Degree of sensitization distance0.50.61.1-0.9-0.31.0-0.7-0.6-0.8-0.90.7-0.50.1-0.6-0.91.0
Degree of sensitization stereotypy1.21.32.4-1.5-0.90.7-1.5-0.3-0.8-1.3-0.6-1.41.0-1.5-1.21.3
Condit. Reinf. active minus inactive responses0.60.62.00.20.9-1.1-0.31.40.70.9-1.1-0.5-0.7-0.30.1-0.9
Condit. Reinf. active-inactive response ratio0.40.51.50.21.0-1.1-0.21.10.40.7-1.2-0.4-0.1-0.20.1-0.7
Condit. Reinf. active responses0.40.51.60.00.5-0.7-0.41.30.70.7-0.6-0.6-1.0-0.40.1-0.8
Condit. Reinf. inactive responses0.20.21.30.1-0.60.30.10.10.60.20.80.1-1.10.10.3-0.2
Incentive salience index mean0.81.03.2-0.11.1-1.3-0.61.80.70.9-1.6-1.0-0.5-0.70.0-1.0
Condit. Reinf. lever presses1.21.75.0-0.70.7-1.3-1.42.20.80.6-2.0-1.8-0.9-1.5-0.3-0.8
Time in familiar zone, hab. session 10.30.20.90.3-0.30.50.5-0.6-0.0-0.11.00.6-0.70.50.50.1
Time in novel zone, hab. session 10.30.20.9-0.10.3-0.7-0.30.80.40.4-0.9-0.50.2-0.4-0.2-0.4
Total zone transitions, hab. session 13.14.310.3-1.5-1.13.2-0.6-2.8-2.7-2.62.8-0.01.3-0.5-1.62.7
Total locomotion distance, hab. session 10.20.30.6-0.6-0.20.8-0.4-0.6-0.8-0.80.5-0.30.3-0.4-0.40.7
Locomotion velocity, hab. session 10.30.40.9-0.5-0.30.9-0.3-0.8-0.8-0.80.8-0.10.3-0.2-0.40.8
Time in familiar zone, hab. session 20.20.21.0-0.2-0.6-0.1-0.40.60.70.2-0.1-0.5-1.0-0.50.0-0.2
Time in novel zone, hab. session 20.40.40.70.90.8-0.80.80.10.20.7-0.50.80.30.80.6-0.7
Total zone transitions, hab. session 21.82.44.3-1.7-1.12.0-1.1-1.6-1.8-2.11.1-0.71.3-1.0-1.62.1
Total locomotion distance, hab. session 20.40.51.6-0.8-0.20.6-0.5-0.7-1.0-0.9-0.1-0.41.3-0.5-0.70.9
Locomotion velocity, hab. session 20.40.61.8-0.8-0.20.6-0.5-0.8-1.1-1.0-0.1-0.31.3-0.4-0.70.9
Novel to familiar place preference ratio0.20.20.70.3-0.60.40.5-0.50.2-0.00.80.5-0.50.50.30.0
Novelty place preference0.10.10.30.1-0.50.10.2-0.10.30.00.30.2-0.50.20.2-0.0
Time in novel zone, NPP test0.10.10.40.0-0.60.1-0.00.00.4-0.00.3-0.0-0.7-0.00.0-0.0
Total zone transitions, NPP test2.23.16.6-1.6-1.62.6-0.8-2.2-2.0-2.32.0-0.41.1-0.8-1.72.3
Total locomotion distance, NPP test0.20.30.90.0-0.40.70.4-1.0-0.5-0.50.80.50.50.4-0.00.4
Locomotion velocity, NPP test0.30.41.00.5-0.10.40.8-1.0-0.3-0.10.81.00.40.90.40.1
Pavlov. Cond. lever latency1.21.53.8-0.6-1.21.90.1-1.9-1.2-1.41.90.50.70.1-0.61.5
Pavlov. Cond. magazine entry latency1.82.37.10.30.8-2.0-0.52.71.91.7-2.0-1.0-1.8-0.60.7-1.7
Pavlov. Cond. change in total contacts1.41.52.91.11.2-1.70.71.51.21.6-1.10.4-0.70.71.0-1.7
Pavlov. Cond. index score1.21.65.00.10.7-1.7-0.62.21.41.2-1.9-1.0-1.2-0.70.3-1.3
Pavlov. Cond. latency score1.51.95.8-0.00.8-1.9-0.82.41.41.2-2.2-1.2-1.1-0.80.2-1.4
Pavlov. Cond. lever contacts0.91.02.90.20.7-1.5-0.31.71.11.0-1.6-0.6-0.7-0.30.4-1.2
Pavlov. Cond. magazine entry number0.91.13.2-0.4-0.71.30.1-1.8-1.3-1.31.00.41.40.1-0.61.4
Pavlov. Cond. intertrial magazine entries1.82.25.2-0.7-1.22.3-0.1-2.3-1.6-1.82.20.41.0-0.0-0.81.8
Pavlov. Cond. lever-magazine prob. diff.1.11.44.50.20.6-1.6-0.52.11.41.2-1.6-0.9-1.3-0.50.4-1.4
Pavlov. Cond. response bias1.11.33.90.30.6-1.5-0.32.01.41.3-1.4-0.7-1.3-0.30.5-1.4
Bone: apparent density0.81.33.3-1.5-1.10.4-1.80.70.2-0.8-0.4-1.8-0.7-1.8-1.00.8
Bone surface0.81.52.4-1.4-1.51.5-1.3-0.6-0.6-1.50.8-1.1-0.1-1.3-1.41.5
Bone volume1.11.93.1-1.7-1.41.6-1.4-0.9-1.0-1.80.8-1.20.3-1.4-1.61.8
Bone: connectivity density1.11.73.4-1.7-1.71.1-1.90.2-0.0-1.20.3-1.8-0.9-1.8-1.31.2
Bone: cortical apparent density1.01.32.51.30.1-0.81.10.71.41.40.40.9-1.61.11.3-1.4
Bone: cortical area0.30.51.00.90.9-0.51.0-0.5-0.30.4-0.21.00.91.00.5-0.4
Bone: cortical porosity1.11.24.00.20.6-1.7-0.51.81.21.0-2.0-0.8-0.6-0.60.3-1.1
Bone: cortical porosity1.11.13.50.40.6-1.7-0.21.71.21.1-1.9-0.5-0.5-0.30.5-1.2
Bone: cortical thickness1.83.06.31.91.8-2.51.41.31.42.1-2.01.1-0.11.41.9-2.2
Bone: cortical thickness2.83.28.61.11.7-2.90.32.41.82.2-2.9-0.2-0.60.31.3-2.2
Bone: cortical tissue density0.81.02.31.10.1-0.71.00.71.31.30.40.8-1.51.01.1-1.2
Bone: elastic displacement0.30.40.90.80.0-0.20.9-0.20.50.60.50.8-0.40.90.7-0.7
Bone: elastic work1.11.42.41.41.1-1.61.30.50.81.4-1.01.00.41.31.3-1.5
Bone: endosteal estimation1.94.19.5-1.0-0.82.8-0.1-3.1-2.7-2.52.30.62.40.0-1.62.5
Bone: endosteal perimeter2.14.49.4-1.2-1.03.1-0.2-3.0-2.7-2.52.80.41.9-0.2-1.92.6
Bone: final force0.61.04.7-0.70.30.5-0.4-1.0-1.5-1.1-0.3-0.22.2-0.3-1.11.1
Bone: final moment0.50.94.0-0.60.20.7-0.2-1.1-1.4-1.0-0.0-0.02.0-0.2-1.01.0
Bone: marrow area1.94.09.3-1.0-0.82.7-0.1-3.1-2.7-2.42.30.62.40.0-1.62.5
Bone: maximum diameter0.50.92.70.10.01.20.6-1.6-1.3-0.81.40.91.00.6-0.40.9
Bone: maximum force0.61.16.2-0.60.50.5-0.2-1.2-1.6-1.1-0.3-0.02.5-0.2-0.91.1
Bone: maximum moment0.61.15.6-0.50.30.7-0.1-1.4-1.6-1.10.00.22.40.0-0.81.1
Bone: minimum diameter1.42.57.0-0.9-0.11.8-0.3-2.2-2.4-1.91.00.22.6-0.2-1.61.9
Bone: periosteal estimation0.91.95.0-0.3-0.01.50.3-2.2-2.0-1.51.20.82.20.4-1.01.5
Bone: periosteal perimeter0.61.02.6-0.20.01.20.3-1.6-1.5-1.11.20.61.30.3-0.71.1
Bone: post-yield work0.50.71.3-1.1-0.20.5-1.1-0.0-0.7-0.9-0.3-1.10.5-1.1-0.90.9
Bone: stiffness2.03.15.6-2.1-0.31.1-2.0-0.7-2.0-2.0-0.6-1.72.3-1.9-2.42.0
Bone: tissue strength0.20.20.40.40.30.00.6-0.5-0.30.00.20.60.60.60.2-0.1
Bone: trabecular number0.60.92.3-1.0-0.9-0.1-1.41.10.7-0.2-0.6-1.5-1.3-1.4-0.40.1
Bone: trabecular spacing0.40.52.20.6-0.10.70.9-0.8-0.20.01.51.0-0.10.90.1-0.0
Bone: trabecular thickness0.30.41.1-0.7-0.1-0.2-0.70.1-0.4-0.5-1.0-0.80.9-0.7-0.60.5
Bone: trabecular tissue density1.52.13.51.91.5-1.61.70.60.91.7-0.71.50.21.71.6-1.7
Breakpoint value in progressive ratio session1.21.42.7-1.7-1.21.1-1.50.1-0.4-1.00.5-1.6-0.8-1.5-1.41.1
Distance traveled before self-admin0.40.51.30.5-0.00.50.9-1.2-0.4-0.20.71.00.80.90.30.3
Distance traveled after self-admin3.84.29.2-1.4-0.42.7-0.4-3.0-2.7-2.61.70.22.7-0.4-1.82.8
Delta time in closed arm before/after self-admin0.90.81.8-0.30.41.3-0.1-1.2-1.3-1.21.10.40.90.0-0.71.1
Delta time in open arm before/after self-admin0.70.71.1-1.0-0.81.1-0.7-0.6-1.0-1.00.8-0.7-0.0-0.7-1.01.0
Diff in mean of infusions in LGA sessions0.80.92.8-0.8-1.00.2-1.21.11.0-0.0-0.1-1.4-1.7-1.3-0.60.1
Extinction: sum of active levers before priming1.71.73.2-1.7-1.31.3-1.8-0.0-0.8-1.30.4-1.6-0.2-1.8-1.71.4
Active lever presses in extinction session 61.61.52.5-1.6-1.21.6-1.3-0.7-0.7-1.41.0-1.2-0.1-1.3-1.51.5
Delta distance traveled before/after self-admin2.72.95.1-2.0-0.51.9-1.5-1.6-1.8-2.30.5-1.21.9-1.5-2.22.2
Delta ambulatory time before/after self-admin1.71.83.2-1.5-0.11.4-1.2-1.2-1.6-1.80.3-0.91.7-1.2-1.71.7
Time in closed arm before self-admin1.11.34.4-0.7-1.0-1.1-1.21.31.20.3-2.1-1.60.2-1.3-0.5-0.4
Time in closed arm after self-admin0.30.31.50.20.3-0.7-0.0-0.00.50.0-1.20.01.0-0.10.0-0.2
Time in open arm before self-admin1.61.84.11.82.0-0.71.8-0.1-0.21.10.31.9-0.21.81.5-1.1
Time in open arm after self-admin0.91.04.10.40.41.11.0-1.3-1.4-0.32.01.1-0.41.10.30.4
Sum of active levers in priming session hrs 5-61.71.74.1-1.5-1.50.5-1.90.90.5-0.6-0.2-2.0-1.3-1.9-1.50.6
Time to tail flick, vehicle, before self-admin1.11.12.7-1.2-1.50.3-1.60.80.3-0.5-0.3-1.6-0.5-1.6-1.20.6
Time to tail flick, vehicle, after self-admin0.10.10.20.00.00.40.0-0.4-0.4-0.40.40.20.30.0-0.20.3
Time to tail flick, test, before self-admin2.72.66.60.71.3-2.6-0.12.41.91.9-2.6-0.7-0.9-0.21.1-1.9
Time to tail flick, test, after self-admin0.60.61.80.2-0.1-1.3-0.21.21.00.9-1.3-0.5-0.5-0.20.4-0.9
Delta time to tail flick, vehicle, before/after SA1.11.02.50.90.90.71.3-1.5-0.9-0.31.31.60.51.30.60.1
Delta time to tail flick, test, before/after SA1.31.24.0-0.5-1.41.70.1-1.5-1.0-1.12.00.40.00.2-0.71.2
Ambulatory time before self-admin0.20.20.60.40.30.10.7-0.7-0.40.00.10.70.80.70.40.1
Ambulatory time after self-admin2.32.56.6-1.40.41.5-1.0-1.7-2.3-2.00.1-0.62.6-1.0-1.82.1
Total heroin consumption2.63.19.8-2.4-1.30.3-2.61.20.2-0.7-0.8-3.1-1.5-2.7-2.00.8
Area under the delay curve0.20.20.60.30.8-0.00.5-0.4-0.70.00.10.60.60.50.2-0.0
Delay disc. indifference point, 0s delay1.41.53.3-0.9-0.41.7-0.5-1.5-1.8-1.71.00.11.3-0.5-1.31.7
Delay disc. indifference point, 16s delay0.50.51.80.2-0.10.90.6-1.0-0.6-0.51.30.80.20.5-0.10.5
Delay disc. indifference point, 2s delay0.30.40.80.60.6-0.80.60.2-0.10.5-0.80.60.90.60.6-0.5
Delay disc. indifference point, 24s delay0.50.51.00.60.9-1.00.40.80.51.0-0.60.2-0.20.40.8-1.0
Delay disc. indifference point, 4s delay0.30.31.0-0.4-0.10.6-0.2-0.8-1.0-0.70.4-0.00.8-0.1-0.50.7
Delay disc. indifference point, 8s delay0.10.10.9-0.01.0-0.10.1-0.1-0.8-0.0-0.10.00.50.1-0.00.0
Delay discount exponential model param0.10.10.7-0.3-0.80.3-0.40.00.5-0.20.2-0.3-0.5-0.4-0.30.2
Delay discount hyperbolic model param0.10.20.6-0.3-0.80.2-0.40.10.6-0.10.2-0.4-0.6-0.4-0.20.1
Fecal boli incidents, locomotor time 10.20.20.60.3-0.3-0.80.10.60.70.6-0.5-0.2-0.30.10.3-0.5
Change in fecal boli incidents, locomotor task0.50.51.20.60.4-0.80.40.71.10.8-0.50.4-0.60.30.7-0.9
Time >=10cm from walls, locomotor time 10.30.31.60.2-0.1-0.80.00.71.30.6-0.8-0.1-0.3-0.10.4-0.6
Bouts of movement, locomotor time 10.60.72.50.3-0.5-0.7-0.11.11.50.7-0.5-0.2-1.6-0.20.5-0.8
Total resting periods, locomotor time 11.31.54.40.80.1-1.30.21.62.01.4-0.90.0-2.10.01.0-1.5
Rest time, locomotor task time 10.60.72.10.9-0.0-0.90.80.51.40.9-0.50.7-0.20.71.0-1.0
Distance moved, locomotor task time 10.91.02.7-0.8-0.11.6-0.4-1.1-1.3-1.21.7-0.2-0.0-0.4-0.81.2
Vertical activity count, locomotor time 10.91.02.0-1.1-0.41.3-0.7-0.9-1.4-1.21.0-0.70.3-0.7-1.11.3
Time >=10cm from walls, locomotor time 20.60.61.10.60.9-1.10.30.90.71.0-0.90.1-0.30.30.9-1.0
Bouts of movement, locomotor time 20.90.92.90.70.3-1.10.21.21.41.1-0.70.0-1.70.10.9-1.2
Total resting periods, locomotor time 20.60.72.20.50.0-0.90.11.11.40.9-0.5-0.1-1.5-0.10.6-1.0
Rest time, locomotor task time 20.91.13.21.1-0.0-1.20.71.01.81.2-0.70.7-0.70.61.1-1.3
Distance moved, locomotor task time 21.51.85.3-0.70.92.00.0-1.7-2.3-1.52.10.40.70.1-0.71.5
Vertical activity count, locomotor time 20.91.04.8-0.91.30.8-0.4-0.9-2.2-0.90.3-0.31.4-0.2-0.81.0
Weight adjusted by age2.42.76.1-1.6-1.92.5-1.0-1.7-1.3-1.92.3-0.7-0.0-0.9-1.62.1
Seeking ratio, delayed vs. immediate footshock0.70.81.31.11.1-1.11.00.40.40.9-0.91.00.40.91.0-0.7
Locomotion in novel chamber1.72.16.11.60.40.72.2-1.4-0.30.22.02.5-0.12.11.5-0.1
Locomotion in novel chamber post-restriction0.30.30.50.70.6-0.70.60.40.20.7-0.30.5-0.30.50.6-0.7
Progressive ratio0.60.72.1-0.30.70.90.1-1.1-1.5-0.80.70.31.30.1-0.30.9
Food seeking constrained by brief footshock0.30.30.90.60.8-0.60.50.4-0.20.4-0.70.70.90.50.6-0.2
Seeking ratio, punishment vs. effort0.81.02.60.8-0.2-1.60.31.41.41.2-1.50.1-0.50.20.8-1.3
Run reversals in cocaine runway, females0.20.20.50.60.7-0.30.50.10.00.4-0.10.5-0.50.50.5-0.5
Run reversals in cocaine runway, males1.31.33.90.3-1.21.50.9-1.8-0.6-1.02.01.30.50.8-0.11.0
Latency to leave start box in cocaine runway0.10.10.50.00.7-0.3-0.00.2-0.40.1-0.50.00.7-0.10.1-0.0
Latency to leave start box in cocaine runway, F0.40.41.0-0.41.0-0.4-0.60.5-0.9-0.0-1.0-0.61.0-0.6-0.30.2
Latency to leave start box in cocaine runway, M0.10.10.5-0.3-0.70.4-0.1-0.5-0.2-0.40.30.00.5-0.1-0.30.4
Cd content in liver1.01.12.3-1.1-1.21.5-0.9-0.9-0.8-1.31.2-0.6-0.1-0.8-1.31.3
Co content in liver0.20.20.4-0.5-0.50.6-0.4-0.3-0.2-0.60.4-0.3-0.1-0.4-0.40.5
Cu content in liver1.61.94.41.10.4-1.80.42.02.11.8-1.1-0.0-1.80.31.0-1.8
Fe content in liver0.40.51.3-0.80.1-0.3-1.00.80.0-0.2-1.0-1.10.2-1.0-0.60.2
K content in liver0.80.83.0-0.80.6-0.6-0.90.6-0.4-0.2-1.7-1.01.4-1.0-1.00.3
Mg content in liver0.00.00.10.20.2-0.10.3-0.2-0.20.1-0.10.20.40.2-0.1-0.0
Mn content in liver0.91.02.60.40.9-1.5-0.11.61.01.2-1.6-0.4-0.3-0.20.4-1.2
Na content in liver0.50.53.10.31.0-0.30.6-0.5-0.80.1-0.50.61.80.50.20.0
Rb content in liver0.60.82.5-0.6-0.91.5-0.2-1.0-0.9-1.01.60.00.1-0.2-0.91.1
Se content in liver0.80.91.81.10.7-1.20.90.80.91.3-0.50.6-0.60.81.3-1.3
Sr content in liver1.21.12.3-1.1-0.91.5-0.9-1.1-1.2-1.51.0-0.50.5-0.7-1.01.3
Zn content in liver0.50.52.50.5-0.8-0.00.40.31.10.50.70.4-1.60.40.6-0.5