Gstp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018237 0.08 0.05 4.9e-08 0.03 0.06 0.06 0.05 5.4e-04 4.2e-07 5.6e-07 1.1e-06
2 BLA gene expression ENSRNOG00000018237 0.2 0.13 1.2e-08 0.13 0.13 0.12 0.13 2.9e-07 1.3e-07 9.2e-07 2.9e-07
3 Brain gene expression ENSRNOG00000018237 0.29 0.15 0.0e+00 0.2 0.17 0.19 0.2 8.1e-18 7.3e-16 1.7e-17 1.3e-18
4 Liver mRNA stability ENSRNOG00000018237 0.07 0.04 7.3e-05 0.03 0.02 0.02 0.03 9.4e-05 3.4e-03 1.4e-03 5.0e-04
5 NAcc gene expression ENSRNOG00000018237 0.09 0.06 3.2e-07 0.07 0.06 0.06 0.05 5.5e-06 2.3e-05 4.1e-05 6.7e-05
6 NAcc mRNA stability ENSRNOG00000018237 0.08 0.06 4.7e-04 0.04 0.04 0.04 0.04 5.6e-04 4.9e-04 9.3e-04 8.5e-04
7 OFC gene expression ENSRNOG00000018237 0.25 0.15 1.8e-04 0.17 0.04 0.17 0.13 7.8e-05 4.5e-02 9.4e-05 5.1e-04
8 PL gene expression ENSRNOG00000018237 0.07 0.05 1.9e-05 0.07 0.06 0.06 0.06 4.1e-06 2.2e-05 1.7e-05 1.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail1.13.611.5-2.10.42.5-2.4-0.43.4-0.2-0.4
BMI without tail0.61.34.4-1.20.31.5-1.4-0.02.1-0.0-0.1
Body weight2.18.718.10.22.83.9-3.72.14.32.42.2
Epididymis fat weight2.55.88.5-0.8-2.4-2.92.9-2.2-2.9-2.1-2.2
Glucose2.63.96.0-2.0-2.3-1.51.6-2.3-1.1-2.4-2.3
Heart weight1.52.23.6-0.7-1.5-1.71.9-1.5-1.4-1.4-1.4
Left kidney weight0.61.74.30.6-0.7-1.92.1-0.6-2.0-0.4-0.5
Right kidney weight0.51.33.51.2-0.2-1.61.7-0.1-1.90.20.0
Tail length1.23.55.51.92.21.3-1.32.11.02.32.2
Length with tail2.48.911.52.13.42.9-2.93.12.73.33.2
Length without tail2.04.45.71.02.32.4-2.32.02.32.12.1
Liver weight, left0.10.10.2-0.1-0.3-0.40.3-0.1-0.5-0.3-0.1
Liver weight, right0.10.20.60.80.3-0.30.40.3-0.50.50.4
Parametrial fat weight2.03.95.2-1.6-2.3-2.01.9-2.1-1.6-2.2-2.2
Retroperitoneal fat weight4.013.421.5-1.2-3.7-4.54.6-3.2-4.4-3.1-3.2
Intraocular pressure0.40.51.41.20.3-0.60.70.5-1.10.50.4
Extensor digitorum longus weight5.421.632.71.94.85.7-5.74.35.14.34.3
Soleus weight2.36.616.00.6-2.0-3.63.7-1.4-4.0-1.5-1.5
Tibialis anterior weight8.930.737.83.96.15.8-6.05.84.65.95.8
Tibia length0.51.52.91.71.40.3-0.61.50.01.51.5
Number of licking bursts0.00.00.1-0.4-0.20.1-0.2-0.10.2-0.3-0.1
Food consumed during 24 hour testing period0.10.10.60.4-0.1-0.50.4-0.0-0.7-0.10.1
Times rat made contact with spout0.30.31.0-0.70.10.6-0.7-0.01.0-0.1-0.1
Mean time between licks in bursts0.70.91.30.51.11.1-0.70.91.11.10.9
Mean num. licks in bursts0.00.00.1-0.2-0.10.00.2-0.20.2-0.1-0.2
Std. dev. time between licks in bursts1.41.72.81.51.50.8-0.71.50.41.71.5
Water consumed over 24 hours0.30.41.1-0.40.30.8-0.90.41.10.10.3
Indifference point 0 sec0.50.81.8-0.3-0.8-1.21.3-0.9-0.8-0.6-0.9
Indifference point AUC1.61.92.40.91.51.5-1.51.61.21.31.5
Indifference point function ln k3.14.48.7-0.4-2.0-2.73.0-1.8-2.6-1.6-1.7
Indifference point function log k3.14.48.7-0.4-2.0-2.73.0-1.8-2.6-1.6-1.7
Delay discounting total patch changes 0 sec0.20.31.10.2-0.2-0.91.1-0.3-0.60.0-0.3
Delay discounting total patch changes 12 sec1.52.03.20.41.51.7-1.81.31.81.21.2
Delay discounting total patch changes 18 sec0.10.10.4-0.20.30.5-0.30.20.60.10.1
Delay discounting total patch changes 24 sec0.91.21.70.81.20.9-0.91.30.91.21.2
Delay discounting total patch changes 6 sec0.20.31.5-0.60.30.7-0.5-0.21.20.1-0.1
Delay discounting time to switch 0 sec1.21.84.0-1.8-0.21.5-1.8-0.62.0-0.7-0.5
Delay discounting water rate 0 sec2.43.810.52.0-0.4-2.72.90.1-3.20.20.1
Delay discounting water rate 12 sec3.14.613.81.9-0.8-3.03.2-0.1-3.7-0.2-0.1
Delay discounting water rate 18 sec0.81.13.00.5-0.7-1.51.6-0.2-1.7-0.3-0.4
Delay discounting water rate 24 sec1.31.84.91.70.0-1.81.80.4-2.20.50.4
Delay discounting water rate 6 sec0.91.43.61.60.2-1.21.40.7-1.90.50.6
Locomotor activity0.50.72.00.6-0.4-1.31.4-0.3-1.3-0.1-0.2
Locomotor testing distance0.61.02.90.5-0.5-1.51.7-0.3-1.5-0.2-0.3
Locomotor testing rearing0.91.42.0-0.8-1.3-1.21.4-1.1-1.0-1.3-1.2
Light reinforcement 10.30.51.70.3-0.6-1.10.9-0.1-1.3-0.5-0.2
Light reinforcement 21.52.04.60.2-1.1-2.01.9-0.8-2.2-0.9-0.8
Reaction time number correct0.91.31.91.21.31.0-0.81.40.51.31.4
Reaction time mean minus median1.01.33.6-0.40.91.6-1.70.11.90.80.3
Reaction time mean minus median AUC1.11.52.60.31.31.5-1.60.71.61.20.9
Reaction time num false alarms0.50.71.51.20.90.10.10.9-0.21.11.0
Reaction time num false alarms AUC0.91.22.11.21.30.8-0.61.20.61.41.3
Reaction time trials correct on left0.91.31.91.21.31.0-0.81.40.51.31.4
Reaction time trials on left1.11.62.31.31.41.1-0.91.50.61.41.5
Reaction time mean0.30.40.9-0.8-0.50.0-0.3-0.90.2-0.7-0.8
Reaction time mean AUC0.40.51.2-0.9-0.7-0.1-0.1-1.10.1-0.8-0.9
Median of all reaction times0.60.81.5-1.1-0.9-0.30.1-1.2-0.1-1.1-1.1
Reaction time omissions1.42.03.10.61.51.7-1.70.91.71.41.2
Reaction time false alarm rate0.20.20.50.70.60.10.00.50.10.70.6
Reaction time premature initiation rate2.02.74.00.61.82.0-1.91.42.01.61.5
Reaction time premature initiations4.05.77.01.42.62.6-2.52.32.32.52.4
Std. dev. reaction times0.30.41.1-0.40.30.7-0.9-0.41.00.3-0.1
Reaction time trials completed1.11.62.31.31.41.1-0.91.50.61.41.5
Reaction time trials AUC0.81.11.71.11.20.9-0.71.30.51.21.3
Social response proportion0.40.51.6-0.50.30.9-0.9-0.31.30.2-0.1
Social responses0.50.71.00.61.01.0-0.90.70.81.00.8
Social time0.50.61.10.10.81.1-0.90.61.10.70.6
Conditioned locomotion3.74.45.92.02.41.8-1.82.41.12.42.4
Cocaine response after cond. corrected0.10.20.2-0.3-0.5-0.40.5-0.4-0.3-0.5-0.4
Cocaine response after cond. not corrected0.40.40.6-0.8-0.8-0.50.5-0.8-0.2-0.8-0.8
Cocaine response before conditioning0.10.10.2-0.4-0.10.2-0.3-0.30.4-0.2-0.3
Saline control response1.92.54.40.21.52.1-2.11.32.11.31.3
Condit. Reinf. active minus inactive responses1.62.03.2-1.6-1.6-1.01.0-1.8-0.4-1.6-1.7
Condit. Reinf. active-inactive response ratio2.42.53.1-1.2-1.8-1.61.6-1.8-1.2-1.7-1.7
Condit. Reinf. active responses1.11.53.2-1.8-1.3-0.40.3-1.60.3-1.4-1.6
Condit. Reinf. inactive responses0.50.61.7-1.0-0.00.9-0.9-0.21.3-0.2-0.3
Condit. Reinf. lever presses0.40.61.6-0.90.01.0-1.0-0.21.3-0.2-0.2
Condit. Reinf. lever reinforcers received0.91.33.2-1.8-1.1-0.10.1-1.40.6-1.3-1.4
Pavlov. Cond. lever latency0.00.00.10.2-0.0-0.10.20.1-0.20.10.0
Pavlov. Cond. magazine entry latency1.51.75.1-0.90.61.8-1.90.42.30.30.4
Pavlov. Cond. change in total contacts0.20.30.9-1.0-0.30.4-0.4-0.40.8-0.5-0.4
Pavlov. Cond. index score0.40.51.5-0.70.21.0-1.00.21.2-0.00.1
Pavlov. Cond. latency score0.30.41.1-0.60.20.8-0.90.11.0-0.00.1
Pavlov. Cond. lever contacts0.10.10.10.30.30.2-0.20.30.10.30.3
Pavlov. Cond. magazine entry number1.82.36.81.0-0.8-2.12.2-0.4-2.6-0.4-0.4
Pavlov. Cond. intertrial magazine entries0.91.22.60.1-0.9-1.51.5-0.7-1.6-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.72.1-0.60.41.2-1.20.31.50.10.2
Pavlov. Cond. response bias0.30.41.2-0.30.40.9-1.00.21.10.30.2
Conditioned reinforcement - actives0.20.20.60.60.0-0.40.5-0.0-0.80.2-0.3
Conditioned reinforcement - inactives4.55.17.7-0.5-2.1-2.62.8-2.2-2.8-1.9-2.3
Conditioned locomotion4.85.714.30.6-1.9-3.33.2-1.3-3.8-1.4-1.6
Intermittent access intake day 1-15 change0.90.92.50.4-0.7-1.31.4-0.2-1.6-0.5-0.4
Intermittent access intake escalation1.01.02.1-0.1-1.0-1.21.4-0.6-1.4-0.9-0.7
Intermittent access intake escalation 20.40.41.10.3-0.5-0.81.0-0.2-1.1-0.4-0.3
Intermitt. access day 1 inactive lever presses1.51.62.3-0.5-1.2-1.51.5-1.4-1.3-1.0-1.4
Intermitt. access day 15 inactive lever presses2.32.53.8-1.0-1.6-1.61.7-1.7-1.4-1.6-2.0
Intermitt. access escalation Index1.51.33.30.2-1.0-1.61.5-0.6-1.8-0.8-0.5
Intermittent access day 1 total infusions6.37.211.8-2.8-3.0-1.92.0-3.4-1.2-3.0-3.3
Intermittent access day 15 total infusions7.58.410.4-1.7-3.1-3.03.2-3.1-2.8-2.9-3.1
Intermittent access terminal intake (last 3 days)6.16.78.5-1.9-2.8-2.52.6-2.9-2.1-2.7-2.9
Intermittent access total infusions4.65.17.7-1.9-2.5-1.92.0-2.7-1.6-2.5-2.8
Intermittent access day 1 locomotion3.53.56.5-2.2-2.0-1.01.0-2.5-0.5-2.1-2.6
Intermittent access day 15 total locomotion4.14.45.2-1.2-2.3-2.22.2-2.1-2.1-2.2-2.2
Intermittent access total locomotion7.07.911.0-2.3-3.2-2.42.4-3.2-2.1-3.1-3.3
Intermittent access standard deviation0.60.61.1-0.1-0.7-1.01.0-0.5-1.0-0.6-0.7
Cocaine induced anxiety0.00.00.00.0-0.0-0.10.1-0.1-0.1-0.2-0.0
Post-drug Anxiety1.21.41.91.01.41.0-0.91.30.91.31.4
Baseline Anxiety2.12.22.91.01.61.5-1.41.71.31.61.7
Lifetime Intake4.04.47.0-1.8-2.3-1.71.8-2.6-1.3-2.2-2.6
Incentive Sensitization - Responses0.40.40.6-0.3-0.6-0.50.6-0.8-0.5-0.6-0.8
Incentive Sensitization - Breakpoint0.50.50.7-0.3-0.7-0.70.8-0.8-0.7-0.7-0.8
Progressive ratio test 1 active lever presses1.41.42.2-0.2-1.0-1.31.5-1.4-1.4-0.7-1.4
Progressive ratio test 1 breakpoint1.11.21.90.0-0.8-1.31.4-1.1-1.4-0.6-1.3
Progressive ratio test 1 inactive lever presses0.60.71.4-0.4-0.7-0.70.8-1.1-0.7-0.7-1.2
Progressive ratio test 2 active lever presses2.83.04.3-0.6-1.6-1.92.1-1.9-1.9-1.4-2.0
Progressive ratio test 2 breakpoint2.83.15.3-0.2-1.5-2.12.3-1.7-2.3-1.2-1.8
Progressive ratio test 2 inactive lever presses7.68.712.2-1.5-3.0-3.03.1-3.3-2.9-2.8-3.5
Total sessions with >9 infusions0.91.01.7-0.7-1.0-0.80.9-1.2-0.7-1.0-1.3
Short access day 1 total inactive lever presses2.62.93.8-0.7-1.7-1.92.0-1.9-1.7-1.5-1.9
Short access day 10 total inactive lever presses1.31.41.8-0.6-1.2-1.31.3-1.2-1.2-1.2-1.2
Short access day 1 total infusions3.13.35.3-1.5-1.9-1.51.8-2.3-1.2-1.8-2.3
Short access day 10 total infusions3.23.56.4-2.4-2.0-0.70.8-2.5-0.1-2.2-2.4
Short access total infusions1.71.93.8-1.5-1.5-0.70.8-2.0-0.3-1.5-1.9
Short access day 1 locomotion2.42.54.3-1.5-1.7-1.21.2-1.9-0.9-1.8-2.1
Short access day 10 total locomotion1.21.32.3-1.2-1.3-0.70.6-1.5-0.5-1.2-1.5
Short access total locomotion1.21.22.6-1.1-1.1-0.60.5-1.5-0.3-1.1-1.6
Compulsive drug intake4.14.05.71.52.42.0-1.92.01.82.41.9
One hour access (0.3 mA shock)6.98.011.9-1.1-2.8-3.23.4-3.0-3.1-2.5-3.0
One hour access (shock baseline)7.89.012.8-1.1-3.0-3.53.6-3.0-3.4-2.7-3.0
Number of responses in last shaping day0.40.40.80.1-0.4-0.60.8-0.7-0.8-0.3-0.9
Context. condit. distance diff. score0.91.11.5-0.7-1.2-1.11.2-1.0-1.0-1.2-1.0
Locomotion velocity, session 10.00.00.0-0.1-0.00.2-0.10.00.1-0.10.0
Locomotion distance, session 10.60.82.1-1.4-0.50.9-0.7-0.61.2-0.8-0.6
Locomotion velocity, session 21.92.23.50.41.51.9-1.91.31.81.31.3
Locomotion distance, session 20.50.72.0-0.60.41.3-1.30.21.40.20.2
Locomotion velocity, session 30.80.92.4-1.6-0.9-0.00.0-1.10.6-1.1-1.1
Locomotion distance, session 30.10.10.1-0.4-0.2-0.0-0.0-0.30.2-0.3-0.3
Stereotopy head waving bouts, day 31.21.42.5-1.6-1.3-0.70.7-1.4-0.1-1.4-1.4
Stereotopy head waving duration, day 31.51.82.3-1.3-1.5-1.31.2-1.5-0.8-1.5-1.5
Locomotion velocity, session 70.60.71.7-1.3-0.90.10.0-1.00.4-1.0-1.0
Locomotion distance, session 70.20.20.7-0.30.20.8-0.60.10.70.10.1
Stereotopy head waving bouts, day 71.41.62.5-1.5-1.4-1.00.9-1.6-0.3-1.4-1.6
Stereotopy head waving duration, day 70.60.72.1-1.5-0.40.5-0.6-0.71.2-0.6-0.8
Locomotion velocity, session 81.11.32.30.21.11.5-1.41.01.40.91.0
Locomotion distance, session 80.30.40.9-0.8-0.8-0.20.4-0.7-0.3-0.9-0.7
Degree of sensitization distance0.20.20.4-0.5-0.00.7-0.5-0.10.7-0.1-0.1
Degree of sensitization stereotypy0.20.30.8-0.9-0.30.1-0.3-0.50.6-0.4-0.5
Condit. Reinf. active minus inactive responses0.20.20.6-0.8-0.30.3-0.2-0.50.5-0.4-0.5
Condit. Reinf. active-inactive response ratio0.20.20.5-0.7-0.5-0.20.2-0.60.1-0.6-0.6
Condit. Reinf. active responses0.00.00.1-0.3-0.20.1-0.0-0.20.1-0.2-0.2
Condit. Reinf. inactive responses0.00.00.10.30.0-0.10.20.0-0.2-0.00.0
Incentive salience index mean0.10.20.3-0.6-0.10.5-0.4-0.20.6-0.3-0.2
Condit. Reinf. lever presses0.10.10.20.30.30.4-0.30.30.10.20.3
Time in familiar zone, hab. session 10.60.60.8-0.7-0.9-0.60.7-0.9-0.5-0.9-0.9
Time in novel zone, hab. session 10.10.10.10.30.30.1-0.20.30.10.40.3
Total zone transitions, hab. session 10.30.41.0-0.20.41.0-0.90.20.90.30.2
Total locomotion distance, hab. session 10.40.60.8-0.6-0.9-0.50.8-0.9-0.7-0.9-0.9
Locomotion velocity, hab. session 10.10.10.2-0.3-0.5-0.10.3-0.4-0.4-0.4-0.4
Time in familiar zone, hab. session 21.11.11.61.11.20.9-0.91.30.51.21.3
Time in novel zone, hab. session 20.90.91.8-1.3-1.0-0.40.4-1.20.1-1.1-1.2
Total zone transitions, hab. session 21.41.84.6-2.1-0.61.2-1.2-0.91.9-1.0-0.9
Total locomotion distance, hab. session 20.71.02.5-1.6-1.00.1-0.0-1.10.4-1.2-1.1
Locomotion velocity, hab. session 20.91.22.5-1.6-1.2-0.20.3-1.30.1-1.4-1.3
Novel to familiar place preference ratio0.20.20.6-0.8-0.30.2-0.3-0.40.5-0.4-0.4
Novelty place preference0.30.30.8-0.9-0.6-0.10.0-0.70.2-0.7-0.7
Time in novel zone, NPP test0.30.30.8-0.9-0.6-0.10.0-0.70.3-0.7-0.7
Total zone transitions, NPP test0.60.92.5-1.00.21.5-1.30.01.6-0.20.0
Total locomotion distance, NPP test0.20.30.7-0.8-0.60.20.0-0.60.1-0.8-0.6
Locomotion velocity, NPP test0.10.20.4-0.6-0.50.20.0-0.50.0-0.6-0.5
Pavlov. Cond. lever latency0.10.20.40.3-0.1-0.60.6-0.2-0.6-0.0-0.2
Pavlov. Cond. magazine entry latency0.81.02.1-1.4-1.1-0.30.3-1.20.2-1.3-1.2
Pavlov. Cond. change in total contacts0.70.81.2-0.9-1.1-0.70.7-1.0-0.5-1.1-1.0
Pavlov. Cond. index score0.00.10.1-0.2-0.3-0.10.2-0.2-0.2-0.4-0.2
Pavlov. Cond. latency score0.10.10.2-0.5-0.4-0.10.1-0.3-0.0-0.5-0.3
Pavlov. Cond. lever contacts0.00.00.1-0.3-0.10.3-0.2-0.00.2-0.2-0.0
Pavlov. Cond. magazine entry number0.00.00.1-0.00.20.3-0.20.10.30.20.1
Pavlov. Cond. intertrial magazine entries0.20.30.70.80.3-0.40.40.4-0.70.40.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.2-0.20.00.0-0.1-0.0-0.3-0.1
Pavlov. Cond. response bias0.00.10.1-0.2-0.3-0.20.2-0.2-0.2-0.3-0.2
Bone: apparent density1.11.85.3-2.3-1.10.4-0.4-1.51.3-1.4-1.3
Bone surface1.32.36.5-1.9-0.01.8-2.0-0.42.5-0.5-0.4
Bone volume0.81.43.9-2.0-0.80.7-0.9-1.01.4-1.1-1.0
Bone: connectivity density1.32.06.1-2.0-0.21.6-1.5-0.62.5-0.6-0.5
Bone: cortical apparent density0.60.81.00.61.01.0-0.80.90.80.90.9
Bone: cortical area0.81.21.61.11.20.8-1.11.30.51.21.3
Bone: cortical porosity0.00.10.1-0.3-0.2-0.30.2-0.10.1-0.3-0.2
Bone: cortical porosity0.10.20.40.10.40.4-0.40.40.60.30.3
Bone: cortical thickness5.49.011.52.63.42.7-3.03.42.03.33.4
Bone: cortical thickness2.42.83.61.21.91.6-1.91.71.31.71.8
Bone: cortical tissue density0.70.91.20.61.11.1-0.91.00.91.01.0
Bone: elastic displacement1.31.54.22.01.1-0.30.31.4-0.91.41.4
Bone: elastic work2.43.14.51.72.11.4-1.32.11.02.12.1
Bone: endosteal estimation2.04.35.7-1.9-2.4-1.71.8-2.4-1.3-2.4-2.4
Bone: endosteal perimeter4.38.811.6-2.6-3.4-2.72.6-3.4-1.9-3.4-3.4
Bone: final force1.01.63.5-0.11.01.7-1.91.01.80.71.0
Bone: final moment0.81.42.9-0.11.01.6-1.70.91.70.70.9
Bone: marrow area2.04.45.8-1.9-2.4-1.81.8-2.4-1.3-2.4-2.4
Bone: maximum diameter0.00.10.30.2-0.2-0.40.3-0.0-0.6-0.1-0.1
Bone: maximum force0.91.54.4-1.50.11.5-1.6-0.22.1-0.4-0.2
Bone: maximum moment0.71.23.8-1.40.11.4-1.5-0.11.9-0.3-0.2
Bone: minimum diameter2.13.85.7-2.2-2.2-1.41.3-2.4-0.7-2.3-2.3
Bone: periosteal estimation0.10.30.4-0.4-0.6-0.50.4-0.6-0.5-0.7-0.6
Bone: periosteal perimeter0.40.60.9-0.9-0.9-0.50.4-1.0-0.3-0.9-0.9
Bone: post-yield work5.16.914.7-3.8-2.9-0.80.8-3.20.5-3.2-3.2
Bone: stiffness0.81.33.0-1.7-0.31.1-1.3-0.61.7-0.7-0.6
Bone: tissue strength0.20.20.4-0.5-0.6-0.40.4-0.4-0.2-0.6-0.6
Bone: trabecular number0.91.44.2-2.0-0.90.5-0.5-1.21.2-1.3-1.1
Bone: trabecular spacing0.30.41.01.00.4-0.2-0.10.7-0.70.50.5
Bone: trabecular thickness1.82.13.5-1.7-1.6-1.01.2-1.9-0.2-1.7-1.7
Bone: trabecular tissue density2.83.910.40.6-1.5-2.82.7-0.9-3.2-1.1-1.0
Breakpoint value in progressive ratio session1.51.73.10.11.21.8-1.71.01.71.01.0
Distance traveled before self-admin0.10.10.2-0.30.00.3-0.20.20.4-0.10.5
Distance traveled after self-admin0.00.00.0-0.2-0.1-0.10.0-0.10.1-0.20.0
Delta time in closed arm before/after self-admin1.21.21.60.91.31.1-1.11.20.81.31.1
Delta time in open arm before/after self-admin0.30.20.5-0.4-0.6-0.50.4-0.7-0.4-0.4-0.5
Diff in mean of infusions in LGA sessions0.50.61.00.50.80.8-0.71.00.60.61.0
Extinction: sum of active levers before priming2.12.15.2-0.31.22.2-1.90.92.30.80.8
Active lever presses in extinction session 62.22.13.01.41.71.1-1.31.60.81.71.7
Delta distance traveled before/after self-admin0.00.00.00.10.0-0.20.0-0.1-0.10.1-0.2
Delta ambulatory time before/after self-admin0.00.10.20.30.30.0-0.20.10.10.40.1
Time in closed arm before self-admin0.30.30.5-0.5-0.7-0.60.3-0.7-0.4-0.6-0.5
Time in closed arm after self-admin0.20.20.30.50.50.2-0.50.40.10.50.4
Time in open arm before self-admin0.40.50.80.50.80.8-0.50.90.60.70.7
Time in open arm after self-admin0.00.00.10.30.20.10.00.20.00.20.2
Sum of active levers in priming session hrs 5-61.91.94.32.11.60.4-0.31.5-0.21.71.7
Time to tail flick, vehicle, before self-admin0.80.82.7-1.6-0.70.5-0.6-0.51.0-0.9-0.6
Time to tail flick, vehicle, after self-admin1.41.53.6-0.21.01.7-1.70.71.90.80.7
Time to tail flick, test, before self-admin1.11.12.7-1.6-1.1-0.0-0.1-1.30.4-1.2-1.2
Time to tail flick, test, after self-admin0.20.20.60.20.30.1-0.60.80.20.30.8
Delta time to tail flick, vehicle, before/after SA0.80.81.30.51.01.2-1.00.71.00.80.7
Delta time to tail flick, test, before/after SA3.33.05.42.11.90.6-1.02.30.22.02.3
Ambulatory time before self-admin0.10.10.3-0.5-0.30.2-0.10.10.3-0.40.0
Ambulatory time after self-admin1.11.22.0-1.3-1.3-0.80.7-1.3-0.3-1.4-1.2
Total heroin consumption3.03.65.80.61.92.4-2.41.62.31.71.7
Area under the delay curve0.60.61.5-1.2-0.9-0.20.1-0.80.2-1.0-1.0
Delay disc. indifference point, 0s delay1.11.22.7-1.6-1.1-0.30.2-1.30.4-1.3-1.4
Delay disc. indifference point, 16s delay1.41.41.7-0.7-1.3-1.31.3-1.1-1.2-1.2-1.3
Delay disc. indifference point, 2s delay0.60.61.1-1.0-1.0-0.60.5-0.7-0.3-1.0-0.9
Delay disc. indifference point, 24s delay0.20.20.40.60.60.10.00.60.10.60.3
Delay disc. indifference point, 4s delay0.20.20.5-0.7-0.4-0.0-0.2-0.20.3-0.5-0.4
Delay disc. indifference point, 8s delay0.20.20.5-0.7-0.30.1-0.0-0.30.4-0.4-0.5
Delay discount exponential model param0.40.41.11.00.70.2-0.00.5-0.30.80.8
Delay discount hyperbolic model param0.30.41.11.00.70.10.00.5-0.30.80.7
Fecal boli incidents, locomotor time 10.00.00.1-0.1-0.2-0.20.1-0.3-0.2-0.0-0.2
Change in fecal boli incidents, locomotor task0.10.10.5-0.30.20.6-0.40.10.70.1-0.1
Time >=10cm from walls, locomotor time 13.83.86.8-2.1-2.1-1.21.2-2.5-0.6-2.3-2.6
Bouts of movement, locomotor time 11.41.52.51.11.31.2-1.01.60.71.31.5
Total resting periods, locomotor time 10.80.91.61.01.00.8-0.61.30.41.01.2
Rest time, locomotor task time 10.70.82.50.8-0.3-1.21.3-0.1-1.6-0.00.1
Distance moved, locomotor task time 10.50.51.5-1.2-0.70.1-0.2-0.90.5-0.9-0.8
Vertical activity count, locomotor time 11.51.62.1-1.0-1.4-1.21.2-1.4-0.9-1.4-1.4
Time >=10cm from walls, locomotor time 20.10.10.10.3-0.1-0.30.3-0.1-0.4-0.1-0.3
Bouts of movement, locomotor time 20.50.50.90.40.80.8-0.80.60.70.90.4
Total resting periods, locomotor time 20.20.20.30.10.40.5-0.50.30.50.50.1
Rest time, locomotor task time 22.32.73.9-1.3-1.8-1.61.6-2.0-1.3-1.7-1.7
Distance moved, locomotor task time 21.01.22.11.01.20.8-0.91.40.71.11.4
Vertical activity count, locomotor time 21.41.53.61.91.40.1-0.21.5-0.31.51.5
Weight adjusted by age1.41.62.90.41.21.7-1.71.21.41.01.1
Seeking ratio, delayed vs. immediate footshock0.30.41.0-1.0-0.50.10.1-0.60.5-0.7-0.7
Locomotion in novel chamber5.36.58.7-1.2-2.7-2.92.9-2.6-2.8-2.5-2.4
Locomotion in novel chamber post-restriction2.32.85.1-0.3-1.6-2.32.1-1.3-2.1-1.3-1.4
Progressive ratio1.41.64.2-1.9-0.31.2-1.5-0.62.1-0.6-0.6
Food seeking constrained by brief footshock0.20.20.4-0.10.40.5-0.50.30.70.40.3
Seeking ratio, punishment vs. effort0.81.02.81.50.2-0.91.10.6-1.70.60.5
Run reversals in cocaine runway, females0.80.82.3-1.2-0.01.1-1.1-0.41.5-0.3-0.5
Run reversals in cocaine runway, males0.80.81.61.21.00.3-0.41.00.11.11.3
Latency to leave start box in cocaine runway0.80.81.8-1.3-1.0-0.20.2-1.10.2-1.2-1.1
Latency to leave start box in cocaine runway, F0.40.41.2-1.1-0.7-0.0-0.1-0.60.3-0.9-0.5
Latency to leave start box in cocaine runway, M0.10.10.1-0.2-0.2-0.00.3-0.3-0.1-0.3-0.3
Cd content in liver0.91.02.40.2-0.8-1.41.3-0.6-1.5-0.7-0.6
Co content in liver0.40.41.31.10.5-0.40.30.6-0.80.60.6
Cu content in liver0.20.20.30.40.50.4-0.50.30.30.50.4
Fe content in liver0.00.00.10.10.20.3-0.10.20.30.10.2
K content in liver0.80.82.3-1.10.11.1-1.2-0.11.5-0.2-0.2
Mg content in liver1.71.84.4-2.1-1.4-0.20.0-1.60.6-1.6-1.6
Mn content in liver1.01.12.80.10.91.5-1.70.71.30.80.7
Na content in liver0.30.30.70.70.60.1-0.20.8-0.10.60.8
Rb content in liver3.03.86.0-2.1-2.1-1.51.5-2.5-0.7-2.2-2.4
Se content in liver0.60.81.4-1.2-1.0-0.40.5-1.0-0.1-1.1-1.1
Sr content in liver3.02.73.31.31.81.7-1.71.81.21.81.8
Zn content in liver0.70.81.50.40.91.0-1.20.81.00.90.8