Hub : Genes

Slc22a6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	ENSRNOG00000018215	0.04	0.03	2.0e-03	0.04	0.03	0.03	0.03	2.6e-04	4.4e-04	9.9e-04	4.5e-04
2	Brain	mRNA stability	ENSRNOG00000018215	0.12	0.06	2.7e-09	0.1	0.1	0.1	0.1	8.4e-10	1.0e-09	2.3e-09	8.9e-10
3	PL	mRNA stability	ENSRNOG00000018215	0.05	0.04	3.0e-04	0.05	0.04	0.04	0.04	1.9e-04	7.8e-04	4.6e-04	3.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	2.0	6.4	7.1	-2.4	2.5	2.7
BMI without tail	1.2	2.4	3.0	-1.5	1.5	1.7
Body weight	3.6	15.4	17.2	-3.8	3.8	4.2
Epididymis fat weight	0.3	0.7	0.9	0.9	-0.9	-0.4
Glucose	2.7	4.2	4.3	2.1	-2.0	-2.0
Heart weight	0.3	0.5	0.6	0.6	-0.7	-0.8
Left kidney weight	0.0	0.0	0.0	0.1	-0.1	0.1
Right kidney weight	0.0	0.0	0.0	0.0	-0.0	0.1
Tail length	1.2	3.5	4.2	-1.8	1.8	2.1
Length with tail	2.4	8.7	9.4	-2.9	2.9	3.1
Length without tail	1.8	3.9	4.0	-1.9	2.0	2.0
Liver weight, left	0.2	0.3	0.3	0.6	-0.5	-0.5
Liver weight, right	0.0	0.1	0.1	-0.2	0.3	0.3
Parametrial fat weight	1.6	3.2	3.2	1.8	-1.8	-1.8
Retroperitoneal fat weight	2.1	7.0	7.6	2.7	-2.8	-2.5
Intraocular pressure	0.1	0.2	0.3	0.4	-0.5	-0.4
Extensor digitorum longus weight	6.4	25.5	27.1	-5.0	5.0	5.2
Soleus weight	2.4	6.9	6.9	2.6	-2.6	-2.6
Tibialis anterior weight	8.6	29.5	30.9	-5.4	5.4	5.6
Tibia length	0.4	1.0	1.2	-0.9	0.9	1.1
Number of licking bursts	0.0	0.0	0.0	0.1	-0.0	-0.0
Food consumed during 24 hour testing period	0.2	0.2	0.3	0.5	-0.4	-0.5
Times rat made contact with spout	0.4	0.5	0.6	-0.7	0.7	0.7
Mean time between licks in bursts	2.3	3.2	3.3	-1.8	1.8	1.7
Mean num. licks in bursts	0.0	0.0	0.0	-0.2	0.1	0.1
Std. dev. time between licks in bursts	0.2	0.2	0.3	-0.5	0.5	0.3
Water consumed over 24 hours	0.7	0.8	0.9	-0.9	0.9	0.9
Indifference point 0 sec	0.5	0.9	0.9	-0.9	0.9	1.0
Indifference point AUC	0.8	0.9	0.9	-1.0	1.0	1.0
Indifference point function ln k	0.8	1.2	1.4	1.0	-1.0	-1.2
Indifference point function log k	0.8	1.2	1.4	1.0	-1.0	-1.2
Delay discounting total patch changes 0 sec	0.7	1.2	1.3	-1.1	1.1	1.1
Delay discounting total patch changes 12 sec	4.4	5.8	5.9	-2.4	2.4	2.4
Delay discounting total patch changes 18 sec	0.2	0.2	0.3	-0.5	0.5	0.4
Delay discounting total patch changes 24 sec	6.8	8.6	8.9	-3.0	2.9	2.9
Delay discounting total patch changes 6 sec	1.2	1.9	2.0	-1.4	1.4	1.3
Delay discounting time to switch 0 sec	0.0	0.1	0.1	-0.3	0.2	0.2
Delay discounting water rate 0 sec	0.1	0.1	0.2	0.3	-0.3	-0.5
Delay discounting water rate 12 sec	0.2	0.4	0.5	0.7	-0.6	-0.5
Delay discounting water rate 18 sec	0.0	0.0	0.0	-0.1	0.1	0.1
Delay discounting water rate 24 sec	0.4	0.6	0.7	0.7	-0.7	-0.9
Delay discounting water rate 6 sec	0.1	0.2	0.3	0.5	-0.4	-0.5
Locomotor activity	0.0	0.0	0.0	0.2	-0.2	-0.2
Locomotor testing distance	0.0	0.0	0.0	0.1	-0.1	-0.1
Locomotor testing rearing	0.2	0.3	0.3	0.5	-0.6	-0.5
Light reinforcement 1	0.0	0.1	0.1	0.2	-0.3	-0.2
Light reinforcement 2	1.1	1.4	1.5	1.2	-1.2	-1.1
Reaction time number correct	1.1	1.6	1.9	-1.2	1.3	1.4
Reaction time mean minus median	0.0	0.1	0.1	0.2	-0.2	-0.3
Reaction time mean minus median AUC	0.0	0.0	0.1	0.2	-0.2	-0.3
Reaction time num false alarms	0.0	0.0	0.1	-0.2	0.2	0.1
Reaction time num false alarms AUC	0.4	0.5	0.6	-0.8	0.8	0.7
Reaction time trials correct on left	1.1	1.6	1.9	-1.2	1.3	1.4
Reaction time trials on left	1.2	1.7	1.9	-1.2	1.3	1.4
Reaction time mean	0.3	0.5	0.7	0.6	-0.6	-0.8
Reaction time mean AUC	0.5	0.6	0.8	0.7	-0.8	-0.9
Median of all reaction times	0.1	0.1	0.2	0.2	-0.3	-0.4
Reaction time omissions	0.0	0.0	0.1	-0.3	0.2	-0.1
Reaction time false alarm rate	0.0	0.0	0.0	0.0	-0.1	-0.2
Reaction time premature initiation rate	5.9	7.9	8.7	-2.8	2.7	2.9
Reaction time premature initiations	7.9	11.2	12.3	-3.3	3.2	3.5
Std. dev. reaction times	0.5	0.7	0.9	0.8	-0.8	-1.0
Reaction time trials completed	1.2	1.7	1.9	-1.2	1.3	1.4
Reaction time trials AUC	1.0	1.5	1.7	-1.1	1.2	1.3
Social response proportion	0.2	0.2	0.3	-0.4	0.4	0.6
Social responses	0.1	0.2	0.2	-0.4	0.4	0.5
Social time	0.0	0.0	0.1	-0.0	0.1	0.3
Conditioned locomotion	0.6	0.7	0.8	-0.9	0.9	0.7
Cocaine response after cond. corrected	0.1	0.1	0.2	0.3	-0.3	-0.5
Cocaine response after cond. not corrected	0.1	0.1	0.2	0.3	-0.4	-0.4
Cocaine response before conditioning	0.0	0.0	0.1	-0.2	0.1	0.3
Saline control response	3.0	3.9	4.4	-1.9	1.9	2.1
Condit. Reinf. active minus inactive responses	0.9	1.1	1.1	1.1	-1.1	-1.0
Condit. Reinf. active-inactive response ratio	2.5	2.6	2.7	1.6	-1.6	-1.6
Condit. Reinf. active responses	0.0	0.0	0.0	0.2	-0.1	0.0
Condit. Reinf. inactive responses	0.8	0.9	1.1	-0.9	0.9	1.1
Condit. Reinf. lever presses	0.4	0.6	0.7	-0.7	0.8	0.8
Condit. Reinf. lever reinforcers received	0.0	0.0	0.0	-0.1	0.1	0.2
Pavlov. Cond. lever latency	0.2	0.3	0.4	0.5	-0.6	-0.6
Pavlov. Cond. magazine entry latency	3.5	4.0	4.1	-2.0	2.0	2.0
Pavlov. Cond. change in total contacts	0.4	0.6	0.7	-0.7	0.8	0.8
Pavlov. Cond. index score	1.4	1.9	1.9	-1.4	1.4	1.4
Pavlov. Cond. latency score	1.2	1.5	1.6	-1.2	1.3	1.2
Pavlov. Cond. lever contacts	0.2	0.2	0.3	-0.5	0.5	0.5
Pavlov. Cond. magazine entry number	5.2	6.5	6.5	2.5	-2.5	-2.5
Pavlov. Cond. intertrial magazine entries	1.9	2.5	2.6	1.6	-1.6	-1.5
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.3	2.4	-1.5	1.5	1.5
Pavlov. Cond. response bias	1.1	1.5	1.5	-1.2	1.2	1.2
Conditioned reinforcement - actives	3.2	3.2	3.4	1.7	-1.8	-1.8
Conditioned reinforcement - inactives	1.3	1.5	1.5	1.2	-1.2	-1.2
Conditioned locomotion	2.2	2.7	3.0	1.6	-1.6	-1.7
Intermittent access intake day 1-15 change	2.0	2.0	2.1	1.4	-1.4	-1.4
Intermittent access intake escalation	1.3	1.3	1.3	1.1	-1.1	-1.1
Intermittent access intake escalation 2	0.2	0.2	0.2	0.4	-0.4	-0.5
Intermitt. access day 1 inactive lever presses	2.2	2.4	2.8	1.7	-1.5	-1.5
Intermitt. access day 15 inactive lever presses	0.0	0.0	0.0	0.2	-0.2	0.0
Intermitt. access escalation Index	0.0	0.0	0.0	0.0	-0.0	-0.1
Intermittent access day 1 total infusions	0.7	0.8	0.9	0.8	-0.9	-0.9
Intermittent access day 15 total infusions	4.1	4.6	4.7	2.1	-2.2	-2.2
Intermittent access terminal intake (last 3 days)	1.1	1.2	1.3	1.0	-1.1	-1.1
Intermittent access total infusions	1.2	1.4	1.5	1.1	-1.2	-1.2
Intermittent access day 1 locomotion	0.0	0.0	0.1	0.1	-0.1	-0.3
Intermittent access day 15 total locomotion	0.3	0.3	0.3	0.5	-0.6	-0.6
Intermittent access total locomotion	0.2	0.3	0.3	0.4	-0.5	-0.6
Intermittent access standard deviation	1.8	1.9	2.1	1.3	-1.4	-1.4
Cocaine induced anxiety	0.1	0.1	0.1	-0.4	0.3	0.3
Post-drug Anxiety	0.3	0.3	0.3	-0.5	0.6	0.6
Baseline Anxiety	1.2	1.3	1.4	-1.1	1.2	1.2
Lifetime Intake	1.0	1.1	1.2	1.0	-1.1	-1.1
Incentive Sensitization - Responses	0.0	0.0	0.0	-0.1	-0.0	-0.0
Incentive Sensitization - Breakpoint	0.0	0.0	0.0	0.0	-0.1	-0.1
Progressive ratio test 1 active lever presses	2.5	2.6	2.8	1.5	-1.6	-1.7
Progressive ratio test 1 breakpoint	2.8	2.9	3.2	1.6	-1.7	-1.8
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.1	-0.3	0.3	0.3
Progressive ratio test 2 active lever presses	2.4	2.5	2.6	1.5	-1.6	-1.6
Progressive ratio test 2 breakpoint	3.6	4.0	4.2	1.9	-2.0	-2.0
Progressive ratio test 2 inactive lever presses	1.1	1.3	1.5	1.1	-1.2	-1.1
Total sessions with >9 infusions	1.2	1.3	1.5	1.1	-1.2	-1.2
Short access day 1 total inactive lever presses	0.6	0.6	0.7	0.8	-0.8	-0.8
Short access day 10 total inactive lever presses	1.6	1.8	1.9	1.4	-1.3	-1.3
Short access day 1 total infusions	0.6	0.7	0.8	0.7	-0.9	-0.8
Short access day 10 total infusions	0.1	0.2	0.2	0.3	-0.4	-0.5
Short access total infusions	0.2	0.3	0.3	0.4	-0.5	-0.6
Short access day 1 locomotion	0.1	0.1	0.2	-0.4	0.4	0.3
Short access day 10 total locomotion	0.0	0.0	0.0	-0.1	0.2	-0.0
Short access total locomotion	0.2	0.2	0.3	-0.5	0.6	0.3
Compulsive drug intake	2.3	2.3	2.5	-1.5	1.5	1.6
One hour access (0.3 mA shock)	4.6	5.3	5.4	2.3	-2.3	-2.3
One hour access (shock baseline)	7.4	8.6	8.9	2.9	-2.9	-3.0
Number of responses in last shaping day	0.0	0.0	0.1	-0.2	0.2	0.1
Context. condit. distance diff. score	0.1	0.1	0.2	0.3	-0.3	-0.4
Locomotion velocity, session 1	0.2	0.2	0.3	-0.5	0.6	0.4
Locomotion distance, session 1	0.8	1.1	1.1	-1.0	1.0	1.0
Locomotion velocity, session 2	2.3	2.7	2.9	-1.6	1.6	1.7
Locomotion distance, session 2	0.3	0.5	0.5	-0.7	0.7	0.7
Locomotion velocity, session 3	0.4	0.5	0.6	-0.7	0.7	0.8
Locomotion distance, session 3	0.3	0.3	0.4	-0.4	0.5	0.6
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	0.4	-0.3	-0.5
Stereotopy head waving duration, day 3	0.1	0.1	0.2	0.3	-0.3	-0.4
Locomotion velocity, session 7	0.1	0.1	0.1	0.4	-0.3	-0.4
Locomotion distance, session 7	0.0	0.0	0.0	0.0	0.1	-0.0
Stereotopy head waving bouts, day 7	0.0	0.0	0.0	0.2	-0.2	-0.2
Stereotopy head waving duration, day 7	1.2	1.5	1.6	-1.2	1.2	1.3
Locomotion velocity, session 8	0.0	0.0	0.1	-0.3	0.2	0.2
Locomotion distance, session 8	0.1	0.2	0.2	0.4	-0.4	-0.4
Degree of sensitization distance	0.1	0.1	0.1	0.2	-0.1	-0.3
Degree of sensitization stereotypy	0.2	0.2	0.3	-0.5	0.4	0.5
Condit. Reinf. active minus inactive responses	1.0	1.1	1.3	-1.0	1.1	1.0
Condit. Reinf. active-inactive response ratio	0.6	0.6	0.7	-0.8	0.9	0.7
Condit. Reinf. active responses	0.4	0.5	0.6	-0.7	0.8	0.7
Condit. Reinf. inactive responses	0.2	0.2	0.2	0.5	-0.4	-0.4
Incentive salience index mean	1.3	1.5	1.6	-1.2	1.3	1.2
Condit. Reinf. lever presses	0.6	0.9	1.0	-0.9	0.9	1.0
Time in familiar zone, hab. session 1	0.2	0.2	0.3	-0.4	0.5	0.4
Time in novel zone, hab. session 1	0.8	0.8	0.9	0.9	-1.0	-0.9
Total zone transitions, hab. session 1	0.2	0.3	0.4	-0.5	0.6	0.6
Total locomotion distance, hab. session 1	0.2	0.2	0.3	0.5	-0.4	-0.6
Locomotion velocity, hab. session 1	0.0	0.0	0.0	-0.0	0.1	-0.0
Time in familiar zone, hab. session 2	0.0	0.0	0.0	-0.1	0.1	0.1
Time in novel zone, hab. session 2	0.2	0.2	0.3	-0.5	0.5	0.4
Total zone transitions, hab. session 2	2.1	2.7	2.9	-1.6	1.6	1.7
Total locomotion distance, hab. session 2	0.2	0.2	0.3	-0.4	0.5	0.5
Locomotion velocity, hab. session 2	0.0	0.0	0.0	-0.1	0.2	0.2
Novel to familiar place preference ratio	1.1	1.1	1.2	-1.0	1.1	1.1
Novelty place preference	0.5	0.5	0.6	-0.7	0.7	0.8
Time in novel zone, NPP test	0.7	0.7	0.7	-0.8	0.8	0.9
Total zone transitions, NPP test	1.4	2.0	2.0	-1.4	1.4	1.4
Total locomotion distance, NPP test	0.1	0.1	0.2	-0.4	0.4	0.3
Locomotion velocity, NPP test	0.0	0.0	0.1	-0.2	0.2	0.1
Pavlov. Cond. lever latency	0.8	1.0	1.1	1.0	-1.0	-1.0
Pavlov. Cond. magazine entry latency	0.4	0.5	0.6	-0.7	0.7	0.8
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	0.1	-0.1	-0.1
Pavlov. Cond. index score	0.2	0.3	0.3	-0.5	0.5	0.6
Pavlov. Cond. latency score	0.3	0.3	0.4	-0.5	0.5	0.6
Pavlov. Cond. lever contacts	0.1	0.2	0.2	-0.4	0.4	0.5
Pavlov. Cond. magazine entry number	0.1	0.2	0.2	0.4	-0.4	-0.4
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.1	0.3	-0.3	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.3	-0.5	0.5	0.6
Pavlov. Cond. response bias	0.2	0.3	0.3	-0.5	0.5	0.6
Bone: apparent density	0.2	0.3	0.3	-0.6	0.6	0.4
Bone surface	0.9	1.6	1.8	-1.3	1.3	1.2
Bone volume	0.2	0.4	0.5	-0.6	0.7	0.5
Bone: connectivity density	1.5	2.3	2.5	-1.6	1.6	1.4
Bone: cortical apparent density	0.4	0.6	0.6	-0.8	0.8	0.7
Bone: cortical area	0.4	0.6	0.7	-0.7	0.7	0.8
Bone: cortical porosity	0.1	0.1	0.1	0.3	-0.3	-0.4
Bone: cortical porosity	0.0	0.0	0.0	-0.1	0.1	0.0
Bone: cortical thickness	3.4	5.6	6.1	-2.3	2.3	2.5
Bone: cortical thickness	1.0	1.2	1.3	-1.1	1.1	1.1
Bone: cortical tissue density	0.5	0.7	0.8	-0.9	0.9	0.7
Bone: elastic displacement	0.1	0.1	0.1	0.3	-0.3	-0.4
Bone: elastic work	1.5	1.9	2.0	-1.4	1.4	1.3
Bone: endosteal estimation	1.5	3.2	3.3	1.8	-1.8	-1.8
Bone: endosteal perimeter	2.9	6.1	6.2	2.5	-2.5	-2.4
Bone: final force	1.6	2.6	2.7	-1.6	1.6	1.6
Bone: final moment	1.5	2.5	2.6	-1.5	1.6	1.6
Bone: marrow area	1.6	3.5	3.6	1.9	-1.9	-1.9
Bone: maximum diameter	0.0	0.0	0.0	0.2	-0.2	-0.1
Bone: maximum force	1.6	2.8	3.0	-1.6	1.7	1.7
Bone: maximum moment	1.6	2.7	2.9	-1.6	1.6	1.7
Bone: minimum diameter	0.9	1.6	1.7	1.3	-1.3	-1.2
Bone: periosteal estimation	0.2	0.4	0.4	0.7	-0.6	-0.6
Bone: periosteal perimeter	0.2	0.3	0.4	0.6	-0.6	-0.5
Bone: post-yield work	0.8	1.1	1.4	1.0	-1.0	-1.2
Bone: stiffness	0.2	0.4	0.4	-0.6	0.6	0.7
Bone: tissue strength	0.1	0.1	0.2	0.4	-0.4	-0.1
Bone: trabecular number	0.5	0.7	0.8	-0.9	0.9	0.8
Bone: trabecular spacing	0.0	0.0	0.1	0.2	-0.3	-0.1
Bone: trabecular thickness	0.6	0.7	1.0	0.7	-0.8	-1.0
Bone: trabecular tissue density	4.2	5.9	6.1	2.4	-2.4	-2.5
Breakpoint value in progressive ratio session	1.2	1.4	1.5	-1.2	1.1	1.2
Distance traveled before self-admin	1.4	1.5	1.6	-1.2	1.3	1.2
Distance traveled after self-admin	0.2	0.2	0.3	-0.3	0.4	0.5
Delta time in closed arm before/after self-admin	3.3	3.2	3.3	-1.8	1.8	1.8
Delta time in open arm before/after self-admin	0.5	0.5	0.6	-0.7	0.7	0.7
Diff in mean of infusions in LGA sessions	1.6	1.8	1.9	-1.3	1.4	1.4
Extinction: sum of active levers before priming	3.6	3.6	3.8	-1.8	1.9	1.9
Active lever presses in extinction session 6	1.6	1.5	1.6	-1.2	1.3	1.2
Delta distance traveled before/after self-admin	0.2	0.2	0.2	0.4	-0.5	-0.3
Delta ambulatory time before/after self-admin	0.4	0.4	0.4	0.6	-0.7	-0.6
Time in closed arm before self-admin	0.2	0.2	0.3	0.4	-0.5	-0.4
Time in closed arm after self-admin	0.2	0.2	0.3	0.4	-0.6	-0.4
Time in open arm before self-admin	0.0	0.0	0.0	0.1	-0.1	-0.2
Time in open arm after self-admin	0.1	0.1	0.1	-0.2	0.3	0.2
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.1	-0.2	0.3	0.3
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.2	-0.5	0.5	0.5
Time to tail flick, vehicle, after self-admin	0.8	0.9	0.9	-0.9	0.9	0.9
Time to tail flick, test, before self-admin	0.7	0.7	0.7	-0.8	0.8	0.8
Time to tail flick, test, after self-admin	0.1	0.1	0.1	0.3	-0.3	-0.3
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.1	-0.3	0.4	0.3
Delta time to tail flick, test, before/after SA	0.3	0.2	0.2	0.5	-0.5	-0.5
Ambulatory time before self-admin	0.8	0.9	1.0	-0.9	0.9	1.0
Ambulatory time after self-admin	0.0	0.0	0.1	-0.1	0.2	0.3
Total heroin consumption	3.2	3.8	4.0	-1.9	1.9	2.0
Area under the delay curve	0.1	0.1	0.1	-0.3	0.3	0.2
Delay disc. indifference point, 0s delay	0.0	0.0	0.0	0.0	-0.0	-0.1
Delay disc. indifference point, 16s delay	0.0	0.0	0.0	-0.2	0.2	0.1
Delay disc. indifference point, 2s delay	0.1	0.2	0.2	0.4	-0.4	-0.4
Delay disc. indifference point, 24s delay	0.4	0.4	0.4	-0.6	0.6	0.7
Delay disc. indifference point, 4s delay	0.9	0.9	1.0	-1.0	1.0	0.9
Delay disc. indifference point, 8s delay	0.0	0.0	0.1	0.2	-0.2	-0.2
Delay discount exponential model param	0.1	0.1	0.1	0.3	-0.2	-0.2
Delay discount hyperbolic model param	0.1	0.1	0.1	0.3	-0.3	-0.3
Fecal boli incidents, locomotor time 1	1.0	1.1	1.2	1.1	-1.0	-1.1
Change in fecal boli incidents, locomotor task	0.0	0.0	0.0	0.1	-0.1	-0.1
Time >=10cm from walls, locomotor time 1	3.7	3.8	4.0	1.9	-1.9	-2.0
Bouts of movement, locomotor time 1	0.0	0.0	0.0	-0.1	-0.0	0.0
Total resting periods, locomotor time 1	0.0	0.0	0.0	-0.0	-0.0	-0.0
Rest time, locomotor task time 1	1.5	1.7	1.7	1.3	-1.3	-1.3
Distance moved, locomotor task time 1	0.3	0.4	0.4	-0.6	0.7	0.6
Vertical activity count, locomotor time 1	0.4	0.4	0.5	0.7	-0.6	-0.7
Time >=10cm from walls, locomotor time 2	0.5	0.6	0.6	0.7	-0.7	-0.8
Bouts of movement, locomotor time 2	1.1	1.2	1.3	-1.1	1.1	1.1
Total resting periods, locomotor time 2	0.5	0.5	0.5	-0.7	0.7	0.7
Rest time, locomotor task time 2	3.2	3.7	3.8	1.9	-1.9	-1.9
Distance moved, locomotor task time 2	0.4	0.5	0.5	-0.7	0.7	0.7
Vertical activity count, locomotor time 2	0.1	0.1	0.1	-0.3	0.2	0.3
Weight adjusted by age	1.3	1.5	1.5	-1.2	1.2	1.2
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.0	-0.2	0.1	0.2
Locomotion in novel chamber	2.9	3.6	3.8	1.9	-1.9	-1.9
Locomotion in novel chamber post-restriction	3.0	3.5	3.7	1.9	-1.8	-1.9
Progressive ratio	0.0	0.0	0.0	0.1	-0.2	0.1
Food seeking constrained by brief footshock	0.0	0.0	0.0	0.0	-0.0	0.0
Seeking ratio, punishment vs. effort	0.0	0.0	0.1	-0.2	0.3	0.1
Run reversals in cocaine runway, females	1.9	1.8	1.9	-1.4	1.3	1.4
Run reversals in cocaine runway, males	0.5	0.5	0.6	0.6	-0.6	-0.7
Latency to leave start box in cocaine runway	0.2	0.3	0.3	0.5	-0.6	-0.4
Latency to leave start box in cocaine runway, F	0.0	0.0	0.0	-0.1	-0.0	0.1
Latency to leave start box in cocaine runway, M	2.6	2.5	2.7	1.6	-1.6	-1.5
Cd content in liver	1.6	1.7	2.3	1.2	-1.2	-1.5
Co content in liver	0.5	0.6	0.8	0.7	-0.7	-0.9
Cu content in liver	0.5	0.6	0.7	-0.8	0.8	0.8
Fe content in liver	0.1	0.1	0.1	0.2	-0.2	-0.3
K content in liver	0.6	0.6	1.0	-0.7	0.7	1.0
Mg content in liver	0.2	0.2	0.4	-0.4	0.5	0.6
Mn content in liver	1.5	1.7	2.1	-1.2	1.2	1.5
Na content in liver	0.2	0.2	0.3	-0.4	0.4	0.5
Rb content in liver	0.8	1.0	1.1	1.1	-1.0	-0.9
Se content in liver	0.0	0.0	0.0	0.2	-0.2	-0.1
Sr content in liver	4.8	4.4	4.4	-2.1	2.1	2.1
Zn content in liver	3.0	3.3	3.6	-1.8	1.9	1.8