Hub : Genes

Ttl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018205 0.44 0.14 0.0e+00 0.26 0.29 0.28 0.29 1.8e-28 4.7e-32 1.6e-31 1.8e-32
2 Adipose mRNA stability ENSRNOG00000018205 0.1 0.06 4.4e-09 0.06 0.06 0.05 0.05 6.9e-07 9.1e-07 5.4e-06 1.9e-06
3 BLA gene expression ENSRNOG00000018205 0.43 0.2 4.8e-13 0.2 0.18 0.21 0.2 4.9e-11 6.6e-10 2.0e-11 4.8e-11
4 Brain gene expression ENSRNOG00000018205 0.17 0.09 3.5e-13 0.11 0.13 0.14 0.14 1.0e-10 3.9e-12 8.4e-13 1.4e-12
5 Brain mRNA stability ENSRNOG00000018205 0.13 0.08 7.8e-09 0.05 0.1 0.09 0.09 3.1e-05 3.4e-09 1.1e-08 1.9e-08
6 IL gene expression ENSRNOG00000018205 0.36 0.22 2.0e-04 0.08 0.01 0.02 -0.01 5.8e-03 1.4e-01 1.2e-01 6.4e-01
7 LHb gene expression ENSRNOG00000018205 0.27 0.23 6.8e-03 0.05 -0 0.03 0.02 2.9e-02 3.5e-01 6.6e-02 9.0e-02
8 Liver alternative TSS ENSRNOT00000024694 0.03 0.02 3.2e-03 0 -0 0.01 -0 7.2e-02 7.4e-01 3.4e-02 6.3e-01
9 Liver alternative TSS ENSRNOT00000109318 0.03 0.02 3.7e-03 0.01 -0 0.01 -0 5.2e-02 9.1e-01 3.3e-02 6.7e-01
10 Liver gene expression ENSRNOG00000018205 0.21 0.1 0.0e+00 0.06 0.14 0.14 0.13 1.2e-07 7.4e-15 4.5e-15 4.6e-14
11 NAcc gene expression ENSRNOG00000018205 0.09 0.06 8.5e-06 0.06 0.06 0.05 0.06 3.3e-05 1.8e-05 8.7e-05 2.8e-05
12 NAcc mRNA stability ENSRNOG00000018205 0.07 0.05 2.5e-04 0.03 0.04 0.04 0.04 2.1e-03 6.0e-04 8.4e-04 1.1e-03
13 PL gene expression ENSRNOG00000018205 0.1 0.09 9.3e-05 0.06 0.04 0.05 0.05 5.0e-05 2.2e-04 1.8e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.82.75.21.82.11.01.52.21.1-2.2-0.80.82.31.41.91.2
BMI without tail2.85.811.02.82.61.92.22.92.3-3.3-1.21.32.82.22.82.0
Body weight4.418.727.35.04.83.94.34.04.4-5.2-3.23.33.94.55.04.1
Epididymis fat weight0.51.22.01.31.30.81.01.21.0-1.4-0.60.61.21.01.30.9
Glucose0.30.40.70.80.20.80.70.20.6-0.6-0.70.60.10.70.70.8
Heart weight5.88.311.43.22.33.33.40.83.3-2.6-3.33.20.83.32.93.3
Left kidney weight1.33.96.32.01.22.42.1-0.22.5-1.3-2.52.4-0.22.31.72.5
Right kidney weight1.13.25.41.81.02.21.8-0.22.2-1.2-2.32.3-0.22.11.62.3
Tail length3.410.117.43.83.42.82.93.33.5-4.2-1.91.93.23.13.72.8
Length with tail3.312.217.94.03.43.73.62.14.2-3.6-3.23.21.93.93.93.7
Length without tail1.02.13.01.51.51.61.60.41.7-1.1-1.71.70.31.71.51.7
Liver weight, left0.91.42.30.8-0.61.51.1-1.31.4-0.1-1.51.4-1.41.10.41.5
Liver weight, right0.00.10.2-0.3-0.4-0.2-0.1-0.3-0.50.20.1-0.1-0.2-0.2-0.3-0.1
Parametrial fat weight0.20.40.7-0.8-0.7-0.8-0.5-0.3-0.70.70.5-0.5-0.2-0.9-0.8-0.8
Retroperitoneal fat weight0.00.10.20.3-0.40.40.4-0.40.3-0.1-0.40.3-0.40.20.00.5
Intraocular pressure0.10.20.60.40.3-0.1-0.20.80.2-0.60.6-0.60.7-0.00.3-0.1
Extensor digitorum longus weight0.10.41.00.70.30.30.30.80.8-1.00.1-0.20.90.30.60.4
Soleus weight0.30.91.91.10.21.20.9-0.01.4-0.9-0.90.8-0.11.10.91.3
Tibialis anterior weight1.13.65.42.31.91.81.91.72.3-2.3-1.31.31.71.92.21.8
Tibia length2.26.315.62.63.41.11.44.01.9-3.6-0.30.43.91.82.91.2
Number of licking bursts0.10.20.70.6-0.50.20.30.30.1-0.90.3-0.40.3-0.00.20.4
Food consumed during 24 hour testing period0.40.41.4-0.5-1.1-0.2-0.4-1.1-0.10.8-0.1-0.0-1.2-0.4-0.7-0.1
Times rat made contact with spout0.00.10.4-0.2-0.2-0.1-0.1-0.30.00.2-0.0-0.0-0.6-0.1-0.2-0.1
Mean time between licks in bursts0.30.40.8-0.5-0.2-0.7-0.90.3-0.70.20.9-0.90.3-0.6-0.4-0.8
Mean num. licks in bursts0.20.31.1-0.70.3-0.1-0.2-0.80.01.1-0.50.6-0.90.0-0.3-0.2
Std. dev. time between licks in bursts0.70.81.41.20.71.00.90.60.8-1.2-0.60.60.51.01.11.1
Water consumed over 24 hours0.00.00.1-0.1-0.3-0.3-0.20.2-0.2-0.10.2-0.3-0.1-0.3-0.1-0.2
Indifference point 0 sec0.60.92.20.5-0.01.20.9-1.01.00.3-1.51.4-1.11.00.40.9
Indifference point AUC0.30.30.60.60.40.60.70.30.7-0.5-0.70.70.30.60.60.5
Indifference point function ln k0.50.71.20.90.51.10.9-0.11.1-0.5-1.00.9-0.21.00.81.0
Indifference point function log k0.50.71.20.90.51.10.9-0.11.1-0.5-1.00.9-0.21.00.81.0
Delay discounting total patch changes 0 sec0.61.02.30.6-0.01.30.9-1.11.10.3-1.51.5-1.21.00.41.0
Delay discounting total patch changes 12 sec0.00.00.1-0.10.1-0.1-0.10.0-0.20.2-0.00.1-0.10.0-0.0-0.3
Delay discounting total patch changes 18 sec0.70.93.5-0.5-1.40.3-0.1-1.70.01.3-0.50.4-1.9-0.2-0.8-0.1
Delay discounting total patch changes 24 sec1.21.66.1-0.3-1.60.80.4-2.40.41.4-1.11.0-2.50.1-0.80.4
Delay discounting total patch changes 6 sec0.91.43.01.00.31.51.4-0.61.4-0.3-1.71.7-0.71.30.81.3
Delay discounting time to switch 0 sec3.75.78.7-2.5-1.8-2.8-2.8-0.3-3.01.82.7-2.7-0.3-2.8-2.4-2.8
Delay discounting water rate 0 sec5.48.511.93.12.33.43.50.63.3-2.4-3.43.30.63.43.03.4
Delay discounting water rate 12 sec1.32.03.41.50.61.81.7-0.21.8-0.9-1.71.7-0.31.61.21.8
Delay discounting water rate 18 sec0.50.61.10.90.90.60.70.70.9-1.0-0.50.50.70.80.90.8
Delay discounting water rate 24 sec0.60.81.41.11.00.81.00.80.9-1.2-0.60.60.80.91.00.8
Delay discounting water rate 6 sec1.82.63.61.91.41.71.81.01.9-1.7-1.51.50.91.91.81.7
Locomotor activity0.40.71.10.91.00.70.70.90.7-0.9-0.50.60.80.91.00.6
Locomotor testing distance0.10.10.20.2-0.10.40.3-0.30.30.1-0.50.4-0.40.30.20.2
Locomotor testing rearing1.01.63.11.20.81.61.3-0.21.6-0.6-1.81.7-0.41.51.11.4
Light reinforcement 10.61.12.01.21.01.11.00.91.4-1.2-0.60.60.81.11.21.1
Light reinforcement 20.30.50.80.80.60.60.70.50.8-0.9-0.50.50.60.70.70.8
Reaction time number correct0.20.30.50.50.00.70.4-0.50.7-0.1-0.60.5-0.50.60.30.7
Reaction time mean minus median0.71.01.7-1.1-1.3-0.8-0.9-1.2-0.91.20.4-0.4-1.1-1.0-1.2-0.8
Reaction time mean minus median AUC0.30.40.8-0.7-0.8-0.4-0.4-0.9-0.50.8-0.00.1-0.8-0.5-0.7-0.4
Reaction time num false alarms2.73.75.62.01.62.32.10.52.4-1.5-2.22.20.42.32.02.2
Reaction time num false alarms AUC2.12.94.01.81.71.91.80.92.0-1.6-1.81.80.82.01.91.8
Reaction time trials correct on left0.20.30.50.50.00.70.4-0.50.7-0.1-0.60.5-0.50.60.30.7
Reaction time trials on left0.20.30.60.50.10.70.5-0.40.7-0.2-0.70.6-0.50.70.40.7
Reaction time mean0.00.10.10.20.30.10.20.30.0-0.3-0.20.30.40.20.20.2
Reaction time mean AUC0.00.00.10.20.30.10.20.20.0-0.3-0.20.30.30.10.20.1
Median of all reaction times0.20.30.50.70.70.50.60.60.4-0.7-0.50.50.60.60.70.5
Reaction time omissions0.60.81.40.71.10.81.00.40.6-0.7-1.11.20.41.10.90.9
Reaction time false alarm rate1.21.82.21.31.51.31.40.91.5-1.2-1.41.50.81.51.51.3
Reaction time premature initiation rate0.10.20.70.60.20.30.30.70.2-0.80.1-0.10.70.30.50.3
Reaction time premature initiations0.10.10.40.60.00.50.30.20.4-0.6-0.10.10.10.40.40.5
Std. dev. reaction times0.10.10.20.40.40.20.40.40.2-0.5-0.30.40.50.30.40.3
Reaction time trials completed0.20.30.60.50.10.70.5-0.40.7-0.2-0.70.6-0.50.70.40.7
Reaction time trials AUC0.20.30.50.50.10.70.5-0.40.7-0.2-0.60.6-0.50.60.30.7
Social response proportion0.70.81.80.70.71.00.8-0.11.0-0.4-1.31.3-0.11.00.71.1
Social responses1.82.34.31.52.11.31.31.41.5-1.6-1.41.51.31.71.81.4
Social time0.20.21.10.21.1-0.00.10.70.3-0.4-0.20.20.70.30.50.0
Conditioned locomotion2.52.94.91.71.72.01.90.21.8-1.1-2.22.20.12.11.71.9
Cocaine response after cond. corrected0.10.10.4-0.3-0.30.0-0.1-0.6-0.10.5-0.20.2-0.6-0.1-0.3-0.1
Cocaine response after cond. not corrected0.20.20.6-0.6-0.3-0.3-0.3-0.5-0.40.80.00.0-0.6-0.3-0.5-0.4
Cocaine response before conditioning0.20.30.5-0.7-0.1-0.7-0.50.0-0.70.50.5-0.50.1-0.6-0.5-0.7
Saline control response3.64.86.52.52.42.12.11.72.5-2.5-1.71.81.62.42.52.2
Condit. Reinf. active minus inactive responses3.44.35.82.32.02.32.20.92.4-1.9-2.22.20.82.42.22.3
Condit. Reinf. active-inactive response ratio3.73.95.32.31.72.12.11.02.2-2.1-2.01.90.92.22.22.2
Condit. Reinf. active responses3.95.47.32.52.62.42.41.42.4-2.3-2.32.31.32.72.62.4
Condit. Reinf. inactive responses0.50.61.10.81.10.90.80.40.8-0.6-0.80.80.41.00.90.8
Condit. Reinf. lever presses1.11.52.31.41.51.01.21.21.1-1.5-0.90.91.21.31.51.2
Condit. Reinf. lever reinforcers received3.34.76.42.42.32.32.31.12.3-2.1-2.22.21.02.52.42.3
Pavlov. Cond. lever latency2.73.75.0-2.2-2.1-1.8-2.0-1.5-2.22.21.5-1.5-1.5-2.1-2.2-1.9
Pavlov. Cond. magazine entry latency0.20.20.50.40.00.60.4-0.20.7-0.2-0.60.6-0.20.50.30.6
Pavlov. Cond. change in total contacts1.62.23.41.71.81.21.31.51.5-1.8-1.01.11.51.51.81.3
Pavlov. Cond. index score1.92.53.61.81.81.41.51.41.7-1.9-1.21.21.41.61.81.5
Pavlov. Cond. latency score1.41.82.51.61.41.31.31.01.6-1.5-1.21.20.91.51.51.4
Pavlov. Cond. lever contacts2.73.75.02.22.11.81.91.52.2-2.2-1.51.51.42.12.22.0
Pavlov. Cond. magazine entry number0.50.61.0-0.9-0.8-0.7-0.7-0.7-1.01.00.6-0.6-0.7-0.8-0.9-0.7
Pavlov. Cond. intertrial magazine entries0.10.20.9-0.1-0.90.1-0.0-0.8-0.20.30.1-0.1-0.7-0.1-0.40.2
Pavlov. Cond. lever-magazine prob. diff.1.51.92.71.61.61.21.31.31.5-1.6-1.01.11.21.41.61.3
Pavlov. Cond. response bias2.94.05.62.32.21.92.01.62.4-2.3-1.61.61.52.22.32.0
Conditioned reinforcement - actives0.70.61.11.00.80.70.90.70.7-1.1-0.50.60.90.80.90.7
Conditioned reinforcement - inactives4.14.68.52.01.32.72.6-0.52.5-1.2-2.92.9-0.32.51.82.5
Conditioned locomotion0.30.40.80.80.40.70.70.40.6-0.8-0.50.50.40.70.70.9
Intermittent access intake day 1-15 change2.42.43.71.91.31.51.91.01.5-1.9-1.31.41.11.71.71.5
Intermittent access intake escalation1.81.82.91.61.21.31.70.91.3-1.7-1.11.21.01.51.51.3
Intermittent access intake escalation 20.50.40.90.80.60.60.90.40.5-0.9-0.60.70.50.70.80.5
Intermitt. access day 1 inactive lever presses1.81.93.31.41.01.61.6-0.01.7-1.0-1.81.80.21.61.31.6
Intermitt. access day 15 inactive lever presses2.02.34.61.10.12.01.6-1.31.9-0.2-2.12.1-1.21.50.81.8
Intermitt. access escalation Index1.11.01.8-1.0-0.5-1.3-1.10.3-1.10.61.2-1.20.2-1.2-0.8-1.3
Intermittent access day 1 total infusions0.30.30.4-0.6-0.6-0.5-0.5-0.4-0.60.60.5-0.5-0.3-0.7-0.7-0.5
Intermittent access day 15 total infusions0.80.91.61.10.71.01.30.40.9-1.1-0.90.90.61.01.01.0
Intermittent access terminal intake (last 3 days)0.70.81.70.90.51.11.3-0.20.9-0.7-1.21.20.01.00.81.0
Intermittent access total infusions0.30.30.50.4-0.00.70.7-0.50.6-0.2-0.70.7-0.30.60.30.6
Intermittent access day 1 locomotion0.30.30.70.50.10.70.6-0.10.5-0.4-0.60.5-0.20.50.40.8
Intermittent access day 15 total locomotion1.71.83.51.20.81.61.7-0.41.3-0.7-1.91.9-0.41.51.11.7
Intermittent access total locomotion1.11.22.31.20.51.41.4-0.11.1-0.9-1.41.3-0.11.21.01.5
Intermittent access standard deviation0.30.30.70.60.40.40.80.40.4-0.8-0.40.40.60.50.60.4
Cocaine induced anxiety4.65.215.2-2.3-3.0-1.0-1.7-3.4-1.43.00.1-0.5-3.9-1.7-2.6-1.4
Post-drug Anxiety1.92.05.1-1.6-1.7-0.9-1.2-1.9-1.11.80.2-0.4-2.3-1.2-1.7-1.1
Baseline Anxiety1.01.03.21.01.40.40.71.50.5-1.4-0.00.21.80.71.10.5
Lifetime Intake0.30.30.60.60.20.70.8-0.10.6-0.4-0.70.7-0.00.60.50.6
Incentive Sensitization - Responses0.00.00.20.00.1-0.00.00.00.0-0.00.2-0.00.50.0-0.00.0
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.1-0.00.0-0.2-0.00.20.1-0.00.3-0.0-0.1-0.0
Progressive ratio test 1 active lever presses2.02.02.91.61.61.31.51.11.3-1.7-1.21.21.11.61.71.4
Progressive ratio test 1 breakpoint2.32.43.51.71.71.41.71.31.4-1.9-1.21.31.31.71.81.5
Progressive ratio test 1 inactive lever presses1.71.83.21.31.01.61.6-0.11.6-0.9-1.81.80.11.61.21.6
Progressive ratio test 2 active lever presses0.50.61.00.70.40.91.0-0.30.9-0.4-0.91.00.10.90.60.9
Progressive ratio test 2 breakpoint0.30.30.60.50.30.60.8-0.10.6-0.3-0.50.70.30.60.40.6
Progressive ratio test 2 inactive lever presses2.52.94.91.61.02.12.0-0.32.1-1.0-2.22.2-0.21.91.42.1
Total sessions with >9 infusions0.00.10.1-0.00.0-0.3-0.00.4-0.3-0.30.3-0.30.3-0.2-0.0-0.3
Short access day 1 total inactive lever presses0.30.30.50.60.40.60.70.10.7-0.5-0.60.70.20.50.50.6
Short access day 10 total inactive lever presses1.21.45.1-0.2-1.20.80.3-2.20.71.2-1.21.1-2.20.3-0.60.7
Short access day 1 total infusions0.00.00.0-0.00.0-0.00.0-0.0-0.00.0-0.10.0-0.2-0.0-0.1-0.1
Short access day 10 total infusions0.00.10.1-0.2-0.3-0.2-0.1-0.1-0.30.10.3-0.3-0.1-0.2-0.2-0.2
Short access total infusions0.00.00.00.1-0.00.00.10.1-0.0-0.2-0.0-0.0-0.00.00.1-0.1
Short access day 1 locomotion0.20.20.7-0.4-0.5-0.1-0.1-0.7-0.20.5-0.20.1-0.9-0.2-0.4-0.2
Short access day 10 total locomotion0.80.91.41.11.10.81.00.90.7-1.2-0.80.80.70.91.11.0
Short access total locomotion0.50.50.90.80.50.80.90.10.6-0.7-1.00.9-0.10.80.70.9
Compulsive drug intake1.01.01.7-1.1-0.9-1.1-1.3-0.3-1.10.91.1-1.1-0.2-1.2-1.0-1.2
One hour access (0.3 mA shock)0.91.01.81.10.81.11.30.21.0-0.9-1.11.20.51.21.01.0
One hour access (shock baseline)0.30.40.80.50.50.60.9-0.00.6-0.4-0.70.80.30.70.50.6
Number of responses in last shaping day0.00.00.1-0.2-0.3-0.2-0.2-0.10.00.10.2-0.2-0.4-0.2-0.2-0.2
Context. condit. distance diff. score2.02.44.81.80.22.21.8-0.51.8-1.1-1.81.7-0.61.71.32.2
Locomotion velocity, session 10.10.10.4-0.50.4-0.3-0.2-0.1-0.50.6-0.20.3-0.3-0.1-0.2-0.4
Locomotion distance, session 11.21.62.91.20.81.61.4-0.31.5-0.6-1.71.7-0.31.51.11.5
Locomotion velocity, session 20.10.10.3-0.40.0-0.3-0.50.0-0.20.40.2-0.2-0.2-0.3-0.2-0.5
Locomotion distance, session 22.73.85.82.01.82.32.20.32.4-1.3-2.42.40.22.31.92.2
Locomotion velocity, session 30.50.62.40.81.20.20.21.60.4-1.10.2-0.21.20.40.90.1
Locomotion distance, session 35.05.49.62.63.01.61.93.02.0-3.1-1.21.22.82.12.81.7
Stereotopy head waving bouts, day 31.51.88.6-1.1-1.5-0.0-0.5-2.3-0.11.9-0.50.3-2.9-0.4-1.2-0.2
Stereotopy head waving duration, day 31.21.54.2-1.4-1.3-0.8-1.0-1.6-0.81.70.4-0.5-2.0-1.0-1.4-0.8
Locomotion velocity, session 71.71.93.31.80.81.71.30.61.6-1.6-1.11.00.41.51.51.7
Locomotion distance, session 74.15.28.92.71.12.92.70.22.5-2.1-2.62.50.12.62.23.0
Stereotopy head waving bouts, day 70.10.20.4-0.20.4-0.5-0.40.7-0.1-0.00.5-0.50.4-0.3-0.0-0.6
Stereotopy head waving duration, day 70.70.81.7-0.90.1-1.2-1.10.6-0.90.51.2-1.10.5-1.0-0.6-1.3
Locomotion velocity, session 80.91.11.91.10.71.31.00.11.2-0.6-1.41.3-0.31.21.01.1
Locomotion distance, session 86.59.715.43.42.03.93.60.23.6-2.4-3.73.60.13.63.03.8
Degree of sensitization distance1.31.35.1-0.1-1.60.90.4-2.30.40.9-1.00.8-2.20.3-0.60.9
Degree of sensitization stereotypy0.80.93.70.51.3-0.30.01.90.1-1.10.6-0.51.90.10.8-0.3
Condit. Reinf. active minus inactive responses0.40.41.20.41.10.10.60.90.4-0.7-0.40.51.00.40.70.3
Condit. Reinf. active-inactive response ratio0.90.91.60.91.10.81.20.51.1-0.8-1.21.20.61.01.00.9
Condit. Reinf. active responses0.10.20.60.30.70.10.40.60.4-0.4-0.10.20.70.30.40.1
Condit. Reinf. inactive responses0.00.00.2-0.1-0.20.10.0-0.40.30.4-0.00.0-0.3-0.0-0.2-0.0
Incentive salience index mean0.30.30.60.50.70.50.80.30.6-0.5-0.70.80.40.60.60.6
Condit. Reinf. lever presses0.10.10.20.40.10.40.50.00.3-0.3-0.40.40.10.40.30.5
Time in familiar zone, hab. session 10.70.61.2-0.8-0.9-0.8-1.1-0.3-0.30.71.0-1.0-0.4-0.9-0.8-0.8
Time in novel zone, hab. session 10.80.81.80.70.51.11.3-0.40.4-0.4-1.41.3-0.41.00.71.1
Total zone transitions, hab. session 11.01.42.91.20.91.51.2-0.01.7-0.7-1.41.3-0.11.41.11.4
Total locomotion distance, hab. session 11.72.56.51.40.52.11.6-0.72.6-0.5-2.01.9-0.91.81.11.8
Locomotion velocity, hab. session 11.82.66.31.40.62.11.7-0.62.5-0.5-2.02.0-0.81.81.21.8
Time in familiar zone, hab. session 20.70.81.3-1.1-1.0-0.8-0.9-0.9-0.81.10.5-0.5-0.8-0.9-1.1-0.8
Time in novel zone, hab. session 20.70.71.21.11.00.80.90.90.7-1.1-0.50.50.70.91.00.7
Total zone transitions, hab. session 22.33.04.21.92.11.61.81.52.0-1.9-1.31.41.51.82.01.6
Total locomotion distance, hab. session 22.83.76.61.71.22.42.3-0.52.5-0.7-2.62.5-0.62.21.52.2
Locomotion velocity, hab. session 22.33.16.31.30.82.22.0-0.92.2-0.3-2.52.5-1.01.91.22.0
Novel to familiar place preference ratio0.30.31.80.0-0.60.40.2-0.90.20.4-0.40.3-1.30.1-0.20.3
Novelty place preference0.30.32.2-0.2-0.80.2-0.1-0.9-0.10.6-0.20.0-1.5-0.2-0.40.0
Time in novel zone, NPP test0.30.31.9-0.1-0.70.30.1-0.80.10.4-0.30.1-1.4-0.0-0.30.1
Total zone transitions, NPP test0.50.81.21.00.80.91.00.61.1-0.9-0.80.80.60.91.00.9
Total locomotion distance, NPP test2.94.07.21.80.82.62.3-0.82.5-0.9-2.72.6-0.92.31.52.5
Locomotion velocity, NPP test2.13.05.51.50.42.22.0-0.92.1-0.6-2.42.3-1.01.91.22.2
Pavlov. Cond. lever latency0.30.41.30.10.4-0.4-0.41.1-0.1-0.60.8-0.81.2-0.20.2-0.3
Pavlov. Cond. magazine entry latency0.60.81.80.80.51.11.2-0.21.0-0.4-1.31.30.11.00.71.0
Pavlov. Cond. change in total contacts0.30.40.80.50.10.70.8-0.40.6-0.3-0.90.9-0.20.60.40.8
Pavlov. Cond. index score0.20.20.80.20.00.50.7-0.50.40.1-0.80.9-0.30.40.10.5
Pavlov. Cond. latency score0.30.41.10.1-0.20.60.7-0.90.30.4-1.01.0-0.80.4-0.00.5
Pavlov. Cond. lever contacts0.30.30.90.30.10.60.8-0.60.40.1-0.91.0-0.40.50.20.6
Pavlov. Cond. magazine entry number0.40.51.5-0.7-0.8-0.4-0.7-0.8-0.60.80.3-0.4-1.2-0.5-0.7-0.5
Pavlov. Cond. intertrial magazine entries0.20.20.40.60.60.40.40.60.6-0.7-0.10.10.60.50.60.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.10.00.40.6-0.40.30.1-0.70.7-0.20.30.10.4
Pavlov. Cond. response bias0.50.60.90.80.60.81.00.30.8-0.8-0.80.90.70.80.80.8
Bone: apparent density2.13.55.02.21.52.12.20.61.9-1.9-2.02.00.62.22.02.2
Bone surface1.42.53.51.81.21.81.80.31.9-1.4-1.81.80.31.91.61.9
Bone volume1.62.74.01.81.22.01.90.31.8-1.5-1.91.80.21.91.72.0
Bone: connectivity density1.11.72.51.51.01.51.60.41.3-1.3-1.51.40.41.51.41.6
Bone: cortical apparent density0.30.41.1-0.20.9-0.6-0.11.0-0.7-0.20.5-0.41.0-0.20.1-0.6
Bone: cortical area2.43.64.82.12.21.82.01.42.0-2.0-1.61.71.32.12.21.8
Bone: cortical porosity2.12.24.2-1.2-0.1-1.9-1.71.1-1.80.62.1-2.01.0-1.6-0.9-2.0
Bone: cortical porosity1.41.53.0-0.70.5-1.5-1.31.5-1.3-0.11.7-1.61.5-1.1-0.3-1.6
Bone: cortical thickness0.60.92.80.81.70.61.01.10.5-0.9-0.70.81.10.91.10.6
Bone: cortical thickness0.10.20.50.20.70.00.10.7-0.1-0.40.1-0.10.70.20.40.0
Bone: cortical tissue density0.30.40.9-0.40.7-0.7-0.20.9-0.8-0.10.6-0.50.9-0.30.0-0.6
Bone: elastic displacement0.80.91.7-0.40.3-1.1-0.81.2-1.0-0.31.3-1.31.2-0.8-0.2-1.0
Bone: elastic work0.20.30.8-0.10.4-0.6-0.30.9-0.5-0.30.7-0.70.9-0.40.0-0.6
Bone: endosteal estimation0.91.94.31.80.41.81.30.32.1-1.5-1.21.00.21.51.41.7
Bone: endosteal perimeter2.14.36.52.51.62.32.10.92.5-2.2-2.01.90.82.42.22.4
Bone: final force2.84.66.12.52.22.22.31.42.2-2.2-2.02.01.32.42.42.2
Bone: final moment2.23.65.02.21.92.02.01.32.1-2.0-1.71.71.22.12.22.0
Bone: marrow area0.91.94.41.80.41.81.30.22.1-1.4-1.21.10.11.51.31.7
Bone: maximum diameter3.66.68.83.02.62.82.71.52.9-2.7-2.42.41.33.02.92.7
Bone: maximum force0.61.01.51.10.81.21.10.31.2-0.9-1.11.10.11.21.01.1
Bone: maximum moment0.30.50.90.80.41.00.80.01.0-0.6-0.80.8-0.10.90.70.9
Bone: minimum diameter0.91.72.61.51.41.31.21.01.6-1.4-1.11.10.81.41.51.3
Bone: periosteal estimation2.04.16.52.51.72.22.01.22.6-2.3-1.71.71.12.32.32.2
Bone: periosteal perimeter2.43.95.32.21.92.12.11.02.2-2.1-2.02.01.02.32.22.2
Bone: post-yield work0.60.91.9-0.9-1.4-0.5-1.0-1.2-0.21.10.6-0.7-1.2-0.8-1.1-0.7
Bone: stiffness1.21.92.81.41.31.61.50.41.4-1.0-1.61.70.21.71.41.5
Bone: tissue strength0.40.40.80.50.10.80.8-0.30.9-0.2-0.90.8-0.30.60.40.7
Bone: trabecular number2.74.16.02.41.62.32.30.92.1-2.2-2.01.90.92.32.22.4
Bone: trabecular spacing0.50.61.2-1.1-0.5-0.8-0.6-0.5-0.91.10.6-0.5-0.5-0.9-0.9-1.0
Bone: trabecular thickness0.70.81.11.01.01.01.00.40.8-0.9-1.01.00.41.11.01.0
Bone: trabecular tissue density1.31.82.81.31.41.41.60.31.2-1.0-1.61.70.41.61.41.5
Breakpoint value in progressive ratio session0.80.92.60.81.60.40.61.40.4-1.2-0.40.51.60.71.10.6
Distance traveled before self-admin5.55.88.42.81.92.82.60.82.9-2.3-2.52.50.42.92.62.8
Distance traveled after self-admin2.62.94.82.21.41.81.81.21.9-2.0-1.41.31.11.91.91.9
Delta time in closed arm before/after self-admin0.30.30.5-0.6-0.6-0.5-0.7-0.4-0.40.60.7-0.7-0.6-0.6-0.6-0.6
Delta time in open arm before/after self-admin1.71.62.31.41.11.41.40.41.4-1.1-1.51.50.41.51.31.5
Diff in mean of infusions in LGA sessions1.01.11.7-1.2-0.9-1.2-1.3-0.4-1.30.81.0-1.0-0.2-1.2-1.1-1.0
Extinction: sum of active levers before priming0.10.10.3-0.20.5-0.3-0.20.6-0.3-0.00.1-0.10.6-0.10.1-0.3
Active lever presses in extinction session 60.20.20.8-0.4-0.5-0.1-0.3-0.7-0.10.6-0.30.2-0.9-0.1-0.4-0.0
Delta distance traveled before/after self-admin0.30.40.7-0.3-0.2-0.7-0.60.5-0.70.10.9-0.80.8-0.7-0.3-0.7
Delta ambulatory time before/after self-admin3.03.24.6-1.8-1.6-2.1-2.0-0.4-2.11.62.1-2.00.0-2.1-1.8-2.1
Time in closed arm before self-admin0.50.61.0-0.8-0.8-0.7-1.0-0.4-0.80.60.8-0.8-0.3-0.9-0.8-0.8
Time in closed arm after self-admin2.02.13.8-1.5-1.3-1.6-1.8-0.1-1.51.01.9-1.9-0.3-1.7-1.4-1.6
Time in open arm before self-admin0.20.20.4-0.3-0.4-0.5-0.40.0-0.40.20.7-0.60.2-0.5-0.4-0.4
Time in open arm after self-admin1.31.42.41.20.41.51.4-0.51.4-0.6-1.51.6-0.31.40.91.5
Sum of active levers in priming session hrs 5-60.50.50.90.60.20.80.7-0.20.8-0.5-0.90.9-0.20.80.60.9
Time to tail flick, vehicle, before self-admin0.70.72.8-0.3-1.10.50.2-1.70.20.7-0.40.3-1.7-0.0-0.60.3
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.2-0.1-0.10.20.0-0.20.3-0.40.2-0.10.00.0
Time to tail flick, test, before self-admin0.40.41.40.60.70.00.41.10.1-0.80.1-0.11.20.30.60.2
Time to tail flick, test, after self-admin0.90.92.9-0.8-1.4-0.3-0.7-1.7-0.41.4-0.0-0.0-1.6-0.6-1.1-0.4
Delta time to tail flick, vehicle, before/after SA1.11.12.31.21.20.60.81.50.9-1.4-0.40.41.30.91.30.8
Delta time to tail flick, test, before/after SA1.00.93.9-0.5-1.30.3-0.3-1.90.21.1-0.40.3-2.0-0.2-0.80.1
Ambulatory time before self-admin3.53.75.32.31.72.12.01.22.3-2.2-1.61.61.22.22.22.2
Ambulatory time after self-admin1.01.12.11.41.10.90.91.30.9-1.4-0.60.51.31.01.31.0
Total heroin consumption1.61.94.11.32.01.21.31.01.3-1.2-1.41.51.01.61.61.3
Area under the delay curve0.30.30.6-0.6-0.4-0.6-0.7-0.2-0.50.60.7-0.6-0.0-0.6-0.6-0.5
Delay disc. indifference point, 0s delay4.65.06.6-2.5-1.9-2.4-2.6-1.3-2.52.32.3-2.3-1.0-2.4-2.4-2.4
Delay disc. indifference point, 16s delay0.30.30.5-0.6-0.7-0.5-0.6-0.5-0.50.70.6-0.6-0.1-0.7-0.7-0.5
Delay disc. indifference point, 2s delay0.10.10.2-0.3-0.4-0.2-0.5-0.3-0.20.40.4-0.4-0.3-0.3-0.4-0.1
Delay disc. indifference point, 24s delay1.01.01.4-1.2-1.0-0.9-1.2-0.8-0.91.20.8-0.7-0.5-1.0-1.2-1.1
Delay disc. indifference point, 4s delay0.20.20.6-0.30.2-0.5-0.50.5-0.4-0.00.8-0.80.8-0.4-0.1-0.3
Delay disc. indifference point, 8s delay0.30.30.7-0.4-0.3-0.6-0.70.2-0.50.20.9-0.80.3-0.6-0.4-0.5
Delay discount exponential model param0.30.30.60.60.40.60.80.10.5-0.5-0.60.60.00.60.50.5
Delay discount hyperbolic model param0.30.30.60.60.40.60.80.10.5-0.5-0.70.6-0.00.60.50.5
Fecal boli incidents, locomotor time 10.20.20.3-0.20.2-0.6-0.50.5-0.5-0.10.5-0.50.6-0.4-0.1-0.4
Change in fecal boli incidents, locomotor task0.00.00.0-0.2-0.0-0.1-0.1-0.1-0.20.20.00.0-0.0-0.1-0.1-0.1
Time >=10cm from walls, locomotor time 10.40.42.00.50.50.00.11.10.2-0.80.4-0.41.40.20.50.2
Bouts of movement, locomotor time 14.34.87.3-2.7-1.6-2.6-2.5-1.0-2.62.32.1-2.0-0.7-2.4-2.3-2.6
Total resting periods, locomotor time 14.14.67.0-2.6-1.4-2.6-2.4-0.7-2.62.12.2-2.1-0.3-2.4-2.2-2.6
Rest time, locomotor task time 10.60.71.2-1.0-0.7-1.0-1.0-0.1-1.10.60.8-0.8-0.1-1.0-0.8-1.0
Distance moved, locomotor task time 10.00.00.10.20.10.20.2-0.00.3-0.0-0.00.10.10.10.10.1
Vertical activity count, locomotor time 10.30.30.60.60.30.70.6-0.00.7-0.4-0.60.5-0.10.60.50.7
Time >=10cm from walls, locomotor time 20.20.20.60.5-0.10.30.30.30.4-0.60.2-0.20.80.20.30.5
Bouts of movement, locomotor time 21.11.12.1-1.0-0.7-1.4-1.10.4-1.20.41.5-1.40.5-1.3-0.8-1.3
Total resting periods, locomotor time 21.21.32.5-1.0-0.5-1.5-1.10.7-1.30.31.6-1.50.8-1.3-0.8-1.4
Rest time, locomotor task time 20.80.92.2-1.0-0.0-1.3-1.00.6-1.50.41.0-0.90.7-1.0-0.6-1.3
Distance moved, locomotor task time 20.30.31.40.1-0.60.60.2-1.20.70.5-0.50.4-0.90.3-0.20.5
Vertical activity count, locomotor time 20.60.61.30.6-0.21.10.6-0.91.20.0-1.00.9-0.90.70.31.1
Weight adjusted by age5.35.98.62.71.62.92.80.52.9-2.2-2.72.70.52.82.52.9
Seeking ratio, delayed vs. immediate footshock0.20.20.5-0.5-0.6-0.3-0.2-0.5-0.30.50.1-0.2-0.7-0.4-0.5-0.4
Locomotion in novel chamber0.30.40.80.80.20.60.50.60.8-0.9-0.30.30.50.60.70.7
Locomotion in novel chamber post-restriction0.80.92.21.01.40.50.51.50.5-1.3-0.50.41.10.81.20.6
Progressive ratio5.05.77.7-2.8-2.5-2.3-2.6-1.8-2.42.71.7-1.9-2.3-2.6-2.8-2.4
Food seeking constrained by brief footshock1.11.42.90.80.21.51.3-1.01.30.0-1.71.7-0.91.30.61.3
Seeking ratio, punishment vs. effort5.16.38.72.82.42.72.91.12.8-2.3-2.42.61.52.92.72.7
Run reversals in cocaine runway, females1.21.22.31.30.41.41.20.21.5-1.1-1.01.00.31.21.11.4
Run reversals in cocaine runway, males1.71.62.61.21.61.11.40.90.9-1.2-1.31.40.91.51.51.2
Latency to leave start box in cocaine runway1.31.42.1-1.4-0.9-1.3-1.5-0.7-1.31.41.1-1.0-0.6-1.3-1.3-1.4
Latency to leave start box in cocaine runway, F2.62.94.5-2.0-1.0-2.0-2.0-0.6-1.91.81.6-1.6-0.7-1.9-1.8-2.1
Latency to leave start box in cocaine runway, M0.30.30.80.4-0.20.70.3-0.90.60.0-0.50.5-0.60.50.10.7
Cd content in liver0.20.20.50.50.60.50.70.40.4-0.5-0.50.50.30.50.60.4
Co content in liver0.91.01.71.11.31.00.90.81.0-1.1-0.90.90.71.21.21.0
Cu content in liver1.11.42.61.21.60.81.01.40.8-1.4-0.60.71.61.11.40.9
Fe content in liver0.20.30.60.70.10.80.5-0.10.6-0.5-0.50.4-0.20.70.50.8
K content in liver0.10.10.40.20.70.00.10.40.4-0.2-0.30.30.50.30.30.1
Mg content in liver1.01.02.01.01.40.80.90.91.0-0.9-0.80.91.01.11.20.8
Mn content in liver1.21.42.91.21.70.80.91.31.3-1.3-0.80.91.21.21.40.9
Na content in liver0.10.10.5-0.3-0.40.0-0.2-0.70.00.5-0.20.1-0.6-0.1-0.30.0
Rb content in liver2.63.25.41.92.31.71.91.31.6-1.9-1.71.70.92.12.11.8
Se content in liver2.12.63.61.81.21.91.80.41.9-1.4-1.81.80.71.91.61.9
Sr content in liver0.90.81.61.20.41.00.80.71.1-1.3-0.30.31.30.91.01.1
Zn content in liver0.30.31.00.20.40.60.6-0.40.60.1-0.91.0-0.10.70.40.6