Klc4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000018168 0.05 0.03 3.2e-05 0.03 0.04 0.03 0.03 5.0e-04 6.0e-05 6.1e-04 1.2e-04
2 BLA gene expression ENSRNOG00000018168 0.1 0.06 2.4e-06 0.12 0.11 0.09 0.11 4.4e-07 1.7e-06 1.5e-05 1.1e-06
3 Brain gene expression ENSRNOG00000018168 0.73 0.08 0.0e+00 0.67 0.66 0.67 0.67 4.9e-83 2.6e-81 1.2e-83 2.5e-84
4 Brain mRNA stability ENSRNOG00000018168 0.06 0.04 3.9e-06 0.07 0.06 0.06 0.06 9.8e-07 3.1e-06 2.5e-06 1.3e-06
5 IL gene expression ENSRNOG00000018168 0.28 0.14 3.1e-05 0.22 0.2 0.22 0.2 6.8e-06 1.4e-05 6.8e-06 1.4e-05
6 LHb gene expression ENSRNOG00000018168 0.18 0.12 1.3e-03 0.03 0.12 0.12 0.1 7.5e-02 9.6e-04 1.2e-03 2.1e-03
7 Liver gene expression ENSRNOG00000018168 0.11 0.07 1.6e-06 0.06 0.04 0.05 0.06 1.2e-07 1.2e-05 3.7e-06 4.2e-07
8 Liver intron excision ratio chr9:14342948:14343345 0.02 0.02 4.1e-03 0.02 0.02 0.01 0.01 2.2e-03 4.4e-03 1.4e-02 6.9e-03
9 PL gene expression ENSRNOG00000018168 0.13 0.07 1.7e-11 0.13 0.14 0.14 0.13 3.7e-10 9.9e-11 1.7e-10 2.8e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail3.812.516.04.03.73.8-3.63.64.00.1-3.83.5
BMI without tail11.524.028.95.45.35.2-5.05.15.4-0.8-5.15.0
Body weight2.811.913.43.73.73.7-3.63.63.6-1.3-3.63.7
Epididymis fat weight2.14.86.21.82.42.3-2.22.21.9-2.3-2.22.5
Glucose4.87.48.92.52.92.9-3.03.02.7-1.3-2.92.9
Heart weight1.21.82.3-1.1-1.4-1.41.4-1.4-1.21.01.3-1.5
Left kidney weight0.20.71.91.40.60.5-0.50.51.01.2-0.60.3
Right kidney weight0.20.53.10.90.1-0.0-0.00.00.51.80.1-0.3
Tail length1.85.56.62.42.52.4-2.42.42.3-1.8-2.32.6
Length with tail0.10.42.00.50.50.5-0.50.50.3-1.4-0.40.7
Length without tail2.55.57.1-2.4-2.6-2.52.4-2.4-2.7-0.12.5-2.3
Liver weight, left0.50.71.41.20.60.7-1.01.01.00.9-0.70.6
Liver weight, right0.60.91.21.00.90.9-1.01.00.9-0.8-0.91.1
Parametrial fat weight5.911.613.63.33.63.6-3.63.63.4-1.7-3.63.7
Retroperitoneal fat weight1.55.18.42.92.32.3-2.22.22.70.5-2.32.1
Intraocular pressure0.91.31.6-1.1-1.2-1.11.2-1.2-1.01.31.0-1.3
Extensor digitorum longus weight0.10.30.60.70.60.6-0.50.60.60.2-0.60.5
Soleus weight0.41.11.41.21.01.1-1.11.11.1-0.6-1.11.1
Tibialis anterior weight0.20.60.70.60.80.9-0.80.80.7-0.5-0.80.8
Tibia length2.26.28.83.02.62.5-2.72.72.90.5-2.52.3
Number of licking bursts3.64.35.71.42.12.2-2.12.11.8-2.2-2.12.4
Food consumed during 24 hour testing period0.60.71.21.10.70.7-0.80.81.00.9-0.70.5
Times rat made contact with spout4.75.46.82.02.52.4-2.62.62.3-1.4-2.42.6
Mean time between licks in bursts1.41.93.8-2.0-1.3-1.31.4-1.4-1.7-0.51.3-1.2
Mean num. licks in bursts0.60.72.2-0.4-0.7-0.80.7-0.7-0.51.50.8-1.0
Std. dev. time between licks in bursts1.82.13.0-1.4-1.4-1.41.7-1.7-1.40.91.4-1.6
Water consumed over 24 hours2.12.44.12.01.61.5-1.61.61.80.2-1.51.5
Indifference point 0 sec0.71.21.51.01.21.1-1.21.21.2-0.4-1.11.1
Indifference point AUC1.11.22.81.60.90.7-0.90.91.41.7-0.70.5
Indifference point function ln k0.40.60.7-0.8-0.8-0.70.8-0.8-0.70.70.7-0.9
Indifference point function log k0.40.60.7-0.8-0.8-0.70.8-0.8-0.70.70.7-0.9
Delay discounting total patch changes 0 sec1.01.62.01.21.41.3-1.31.31.4-0.4-1.31.3
Delay discounting total patch changes 12 sec1.01.33.01.71.21.0-1.01.01.40.6-0.90.9
Delay discounting total patch changes 18 sec1.41.83.51.91.41.2-1.31.31.70.7-1.21.2
Delay discounting total patch changes 24 sec0.81.01.91.41.21.0-0.90.91.20.4-0.90.9
Delay discounting total patch changes 6 sec2.03.04.02.01.91.7-1.81.81.9-0.5-1.71.8
Delay discounting time to switch 0 sec4.56.910.3-3.2-2.6-2.62.7-2.7-3.2-1.22.7-2.3
Delay discounting water rate 0 sec2.94.69.53.12.01.8-1.81.82.72.4-1.91.4
Delay discounting water rate 12 sec5.27.710.93.32.92.9-2.82.83.20.4-2.92.7
Delay discounting water rate 18 sec1.21.62.51.61.41.2-1.21.21.50.5-1.21.1
Delay discounting water rate 24 sec1.92.63.81.91.61.6-1.61.62.00.9-1.71.4
Delay discounting water rate 6 sec0.50.73.11.10.50.4-0.40.40.91.8-0.50.2
Locomotor activity2.33.64.51.61.91.9-2.12.11.7-1.8-1.92.1
Locomotor testing distance2.03.24.11.51.81.8-1.91.91.6-1.9-1.82.0
Locomotor testing rearing3.04.76.32.52.22.2-2.32.32.5-0.1-2.22.1
Light reinforcement 11.93.54.72.21.91.9-2.02.02.1-0.1-2.01.8
Light reinforcement 22.73.64.51.51.92.0-2.02.01.6-1.8-2.12.1
Reaction time number correct0.30.52.90.3-0.3-0.40.4-0.40.11.70.4-0.6
Reaction time mean minus median0.10.20.4-0.3-0.4-0.40.2-0.2-0.5-0.70.5-0.3
Reaction time mean minus median AUC0.40.50.9-0.9-0.7-0.70.5-0.5-0.9-0.90.8-0.5
Reaction time num false alarms0.70.91.2-1.0-1.1-1.01.1-1.1-1.00.11.0-0.9
Reaction time num false alarms AUC0.50.70.9-0.7-0.9-0.80.9-0.9-0.80.30.8-0.9
Reaction time trials correct on left0.30.52.90.3-0.3-0.40.4-0.40.11.70.4-0.6
Reaction time trials on left0.30.42.50.3-0.2-0.40.4-0.40.11.60.3-0.6
Reaction time mean0.70.95.9-1.1-0.4-0.20.2-0.2-0.9-2.40.20.1
Reaction time mean AUC0.70.96.4-1.1-0.3-0.10.1-0.1-0.8-2.50.10.2
Median of all reaction times0.60.85.9-1.0-0.20.00.0-0.0-0.7-2.4-0.10.3
Reaction time omissions0.50.71.30.60.80.8-0.90.90.7-1.1-0.90.9
Reaction time false alarm rate0.60.91.3-1.2-1.0-0.90.9-0.9-1.1-0.60.9-0.7
Reaction time premature initiation rate0.91.31.61.21.21.3-1.11.11.2-0.4-1.31.2
Reaction time premature initiations0.81.22.21.51.11.1-0.90.91.40.6-1.10.9
Std. dev. reaction times0.50.74.4-0.9-0.4-0.30.3-0.3-0.8-2.10.4-0.0
Reaction time trials completed0.30.42.50.3-0.2-0.40.4-0.40.11.60.3-0.6
Reaction time trials AUC0.30.42.50.5-0.1-0.20.2-0.20.31.60.2-0.4
Social response proportion0.91.01.4-1.0-1.1-0.91.1-1.1-1.2-0.40.9-0.9
Social responses2.02.63.5-1.5-1.7-1.71.9-1.9-1.8-0.41.6-1.6
Social time1.72.25.9-0.3-1.5-1.41.4-1.4-0.82.41.3-1.7
Conditioned locomotion1.92.24.4-0.8-1.4-1.51.5-1.5-1.12.11.5-1.7
Cocaine response after cond. corrected0.20.30.4-0.6-0.6-0.50.5-0.5-0.50.20.5-0.5
Cocaine response after cond. not corrected0.40.40.6-0.7-0.7-0.70.6-0.6-0.70.50.7-0.8
Cocaine response before conditioning0.10.10.50.50.10.1-0.10.10.40.7-0.2-0.0
Saline control response0.00.00.00.2-0.1-0.0-0.10.10.10.00.1-0.1
Condit. Reinf. active minus inactive responses0.10.10.9-0.30.10.1-0.20.2-0.1-1.0-0.00.3
Condit. Reinf. active-inactive response ratio0.91.02.20.30.90.9-1.11.10.6-1.5-0.91.1
Condit. Reinf. active responses0.00.00.2-0.20.0-0.00.0-0.0-0.1-0.40.10.1
Condit. Reinf. inactive responses0.10.10.50.2-0.1-0.20.4-0.4-0.00.70.3-0.3
Condit. Reinf. lever presses0.50.71.70.50.90.9-0.80.80.6-1.3-0.81.0
Condit. Reinf. lever reinforcers received0.00.00.2-0.2-0.0-0.10.1-0.1-0.2-0.50.10.0
Pavlov. Cond. lever latency2.53.44.7-1.5-1.9-1.91.8-1.8-1.62.21.9-2.1
Pavlov. Cond. magazine entry latency1.82.12.61.31.51.5-1.41.41.2-1.5-1.61.6
Pavlov. Cond. change in total contacts2.43.45.11.51.91.9-1.81.81.5-2.3-1.82.1
Pavlov. Cond. index score4.45.77.02.22.52.5-2.42.42.2-2.2-2.52.6
Pavlov. Cond. latency score4.76.07.42.22.52.6-2.42.42.3-2.2-2.62.7
Pavlov. Cond. lever contacts2.73.84.81.62.02.0-1.81.81.7-2.2-2.02.2
Pavlov. Cond. magazine entry number0.91.12.1-0.9-1.0-1.00.8-0.8-0.81.41.1-1.2
Pavlov. Cond. intertrial magazine entries0.00.10.50.0-0.1-0.1-0.10.10.10.70.1-0.1
Pavlov. Cond. lever-magazine prob. diff.4.45.77.02.12.52.5-2.32.32.1-2.3-2.52.6
Pavlov. Cond. response bias1.11.54.00.91.21.2-1.01.00.8-2.0-1.11.4
Conditioned reinforcement - actives0.90.91.4-0.3-1.0-1.01.1-1.1-0.61.20.9-1.1
Conditioned reinforcement - inactives0.70.81.71.30.80.9-0.70.71.20.6-1.00.7
Conditioned locomotion0.00.00.00.1-0.10.10.1-0.10.1-0.2-0.10.0
Intermittent access intake day 1-15 change0.10.10.30.60.10.1-0.10.10.30.1-0.20.1
Intermittent access intake escalation0.00.00.00.2-0.0-0.10.1-0.10.0-0.2-0.0-0.1
Intermittent access intake escalation 20.10.10.40.60.20.2-0.10.10.40.4-0.20.1
Intermitt. access day 1 inactive lever presses1.31.42.11.31.31.3-1.11.11.3-0.2-1.51.2
Intermitt. access day 15 inactive lever presses1.71.93.01.51.41.6-1.31.31.50.0-1.71.4
Intermitt. access escalation Index0.00.00.1-0.2-0.1-0.00.1-0.0-0.10.2-0.0-0.1
Intermittent access day 1 total infusions0.70.81.10.50.81.0-0.80.80.7-1.1-1.11.0
Intermittent access day 15 total infusions0.40.40.90.40.50.8-0.50.50.5-0.9-0.90.7
Intermittent access terminal intake (last 3 days)0.30.31.20.20.30.7-0.30.30.3-1.1-0.70.5
Intermittent access total infusions0.20.31.10.00.20.6-0.30.20.2-1.1-0.70.5
Intermittent access day 1 locomotion0.30.30.50.00.50.7-0.60.50.3-0.5-0.70.7
Intermittent access day 15 total locomotion0.30.30.50.50.50.7-0.50.50.6-0.1-0.70.6
Intermittent access total locomotion0.10.10.7-0.40.10.4-0.20.1-0.1-0.9-0.40.4
Intermittent access standard deviation3.13.34.5-2.1-1.9-1.72.0-1.9-2.1-0.81.8-1.6
Cocaine induced anxiety0.10.10.30.10.40.4-0.40.40.2-0.5-0.40.4
Post-drug Anxiety0.20.21.6-0.40.10.0-0.10.1-0.3-1.3-0.10.2
Baseline Anxiety0.20.20.3-0.4-0.5-0.60.5-0.5-0.5-0.30.4-0.4
Lifetime Intake0.10.10.3-0.4-0.30.00.3-0.3-0.3-0.5-0.1-0.1
Incentive Sensitization - Responses1.21.21.91.41.01.2-1.00.91.30.1-1.31.0
Incentive Sensitization - Breakpoint1.21.22.01.41.01.2-1.01.01.30.2-1.31.0
Progressive ratio test 1 active lever presses1.31.32.20.61.11.2-1.11.00.9-1.5-1.31.3
Progressive ratio test 1 breakpoint1.01.01.50.71.01.1-1.00.90.9-1.1-1.21.1
Progressive ratio test 1 inactive lever presses0.91.01.61.20.91.2-0.90.81.2-0.1-1.30.9
Progressive ratio test 2 active lever presses1.11.21.91.31.01.3-1.10.91.3-0.2-1.41.1
Progressive ratio test 2 breakpoint1.71.92.71.61.31.6-1.41.21.6-0.2-1.71.3
Progressive ratio test 2 inactive lever presses0.50.61.10.90.60.9-0.60.50.9-0.1-1.00.7
Total sessions with >9 infusions0.00.00.10.1-0.20.00.2-0.20.10.2-0.1-0.2
Short access day 1 total inactive lever presses0.20.21.00.60.10.3-0.10.10.51.0-0.30.0
Short access day 10 total inactive lever presses0.91.01.81.30.91.0-0.80.81.20.8-1.10.8
Short access day 1 total infusions0.40.40.6-0.4-0.7-0.50.7-0.8-0.50.50.5-0.7
Short access day 10 total infusions0.20.21.4-0.4-0.00.20.0-0.0-0.2-1.2-0.40.2
Short access total infusions0.30.40.6-0.8-0.7-0.50.7-0.7-0.7-0.30.4-0.6
Short access day 1 locomotion0.60.60.8-0.8-0.9-0.70.9-0.9-0.80.10.7-0.8
Short access day 10 total locomotion2.02.24.1-2.0-1.5-1.41.4-1.5-1.9-0.51.4-1.3
Short access total locomotion2.12.12.6-1.5-1.6-1.51.6-1.6-1.60.71.4-1.5
Compulsive drug intake0.20.21.50.2-0.2-0.30.2-0.20.11.20.4-0.4
One hour access (0.3 mA shock)0.40.41.2-0.0-0.6-0.60.7-0.7-0.21.10.6-0.7
One hour access (shock baseline)0.20.20.40.30.40.6-0.40.40.4-0.6-0.60.6
Number of responses in last shaping day0.10.10.30.60.30.3-0.30.20.50.5-0.30.2
Context. condit. distance diff. score0.20.31.00.30.40.4-0.40.40.3-1.0-0.40.6
Locomotion velocity, session 10.70.81.61.30.70.6-0.80.81.11.2-0.70.4
Locomotion distance, session 12.22.83.41.81.71.8-1.81.81.8-0.6-1.81.7
Locomotion velocity, session 25.46.39.33.12.62.5-2.72.72.80.1-2.52.4
Locomotion distance, session 21.31.92.71.61.31.4-1.51.51.60.2-1.51.3
Locomotion velocity, session 30.60.71.51.20.70.6-0.70.71.01.2-0.50.4
Locomotion distance, session 30.91.01.8-0.5-1.0-0.91.0-1.0-0.71.31.0-1.1
Stereotopy head waving bouts, day 31.21.41.81.21.31.3-1.21.21.3-0.2-1.31.3
Stereotopy head waving duration, day 31.92.33.21.71.61.6-1.61.61.80.4-1.51.5
Locomotion velocity, session 70.40.41.61.00.40.4-0.30.30.71.3-0.40.2
Locomotion distance, session 70.20.31.40.70.20.2-0.20.20.51.2-0.30.0
Stereotopy head waving bouts, day 70.20.30.50.40.50.5-0.50.50.4-0.7-0.50.6
Stereotopy head waving duration, day 70.10.21.1-0.5-0.1-0.10.1-0.1-0.4-1.10.20.0
Locomotion velocity, session 80.60.71.01.00.80.7-1.01.00.8-0.3-0.70.8
Locomotion distance, session 81.01.51.81.31.21.3-1.31.31.2-0.7-1.31.3
Degree of sensitization distance1.81.82.41.51.41.4-1.41.41.5-0.0-1.51.3
Degree of sensitization stereotypy0.50.50.7-0.8-0.7-0.60.7-0.7-0.9-0.80.7-0.5
Condit. Reinf. active minus inactive responses1.51.72.11.31.41.4-1.41.41.4-0.3-1.41.4
Condit. Reinf. active-inactive response ratio0.30.30.40.30.60.5-0.60.60.5-0.5-0.50.6
Condit. Reinf. active responses2.73.23.81.92.01.9-1.91.91.9-0.7-1.91.9
Condit. Reinf. inactive responses2.22.53.11.61.71.7-1.61.61.6-0.8-1.71.8
Incentive salience index mean2.12.53.61.91.71.6-1.61.61.8-0.1-1.61.6
Condit. Reinf. lever presses3.74.96.92.62.42.3-2.22.22.5-0.4-2.22.3
Time in familiar zone, hab. session 10.70.71.81.30.60.7-0.50.51.01.0-0.80.5
Time in novel zone, hab. session 10.80.81.7-1.3-0.9-0.90.7-0.7-1.0-0.10.9-0.8
Total zone transitions, hab. session 13.95.66.92.52.42.6-2.42.42.5-0.8-2.62.5
Total locomotion distance, hab. session 14.15.98.02.82.62.5-2.52.52.7-0.1-2.52.4
Locomotion velocity, hab. session 13.75.37.42.72.42.4-2.42.42.6-0.1-2.42.3
Time in familiar zone, hab. session 22.02.12.9-1.7-1.6-1.41.6-1.6-1.7-0.71.4-1.2
Time in novel zone, hab. session 20.50.50.90.80.60.5-0.70.70.81.0-0.60.3
Total zone transitions, hab. session 22.93.74.91.32.02.0-2.02.01.6-2.0-2.02.2
Total locomotion distance, hab. session 23.04.04.81.72.12.2-2.12.12.0-1.2-2.22.2
Locomotion velocity, hab. session 22.43.24.01.51.91.9-1.91.91.7-1.3-1.92.0
Novel to familiar place preference ratio0.10.10.10.30.30.3-0.30.30.3-0.0-0.30.3
Novelty place preference0.00.00.00.20.10.0-0.10.10.1-0.0-0.00.1
Time in novel zone, NPP test0.00.00.00.10.1-0.0-0.10.10.10.2-0.00.0
Total zone transitions, NPP test6.79.511.03.13.23.3-3.33.33.1-1.7-3.33.3
Total locomotion distance, NPP test5.88.09.42.73.03.0-3.03.02.8-1.6-3.03.1
Locomotion velocity, NPP test6.39.010.92.83.13.1-3.23.22.9-2.1-3.13.3
Pavlov. Cond. lever latency2.32.95.3-2.3-1.7-1.71.6-1.6-2.0-0.21.7-1.6
Pavlov. Cond. magazine entry latency0.81.12.51.60.90.8-0.70.71.31.4-0.90.5
Pavlov. Cond. change in total contacts2.02.13.51.91.51.5-1.31.31.80.6-1.51.2
Pavlov. Cond. index score2.43.16.22.51.71.7-1.61.62.10.6-1.71.5
Pavlov. Cond. latency score1.72.25.02.21.41.4-1.31.31.80.8-1.41.2
Pavlov. Cond. lever contacts3.23.86.52.52.02.0-1.91.92.3-0.0-2.01.9
Pavlov. Cond. magazine entry number1.72.24.4-2.1-1.5-1.41.3-1.3-1.8-0.71.5-1.2
Pavlov. Cond. intertrial magazine entries0.81.01.4-1.2-1.1-1.01.0-1.0-1.1-0.01.1-1.0
Pavlov. Cond. lever-magazine prob. diff.2.32.85.82.41.71.6-1.51.52.10.8-1.71.4
Pavlov. Cond. response bias3.94.87.92.82.32.2-2.12.12.60.3-2.32.0
Bone: apparent density0.40.71.7-1.2-0.6-0.60.7-0.7-1.0-1.30.7-0.4
Bone surface1.32.33.6-1.9-1.5-1.41.6-1.6-1.8-0.91.4-1.2
Bone volume0.50.91.5-1.2-0.9-0.90.9-0.9-1.2-0.80.9-0.7
Bone: connectivity density0.91.43.1-1.8-1.0-0.91.0-1.0-1.5-1.60.9-0.6
Bone: cortical apparent density0.70.91.3-0.8-1.0-1.10.9-0.9-1.00.31.1-1.0
Bone: cortical area0.60.92.31.50.80.9-0.80.81.10.4-0.80.8
Bone: cortical porosity0.10.10.20.20.30.4-0.30.30.3-0.1-0.40.4
Bone: cortical porosity0.10.10.40.40.20.3-0.20.20.40.6-0.30.2
Bone: cortical thickness0.81.43.31.81.11.1-1.11.11.40.4-1.11.0
Bone: cortical thickness0.00.00.2-0.2-0.1-0.00.0-0.1-0.2-0.50.00.1
Bone: cortical tissue density0.60.81.1-0.7-0.9-1.00.9-0.9-0.90.21.1-1.0
Bone: elastic displacement0.30.30.5-0.5-0.5-0.70.5-0.5-0.6-0.00.7-0.5
Bone: elastic work0.10.10.90.10.20.1-0.20.2-0.0-0.9-0.00.3
Bone: endosteal estimation0.40.91.2-1.1-1.0-0.91.0-1.0-1.0-0.10.9-0.9
Bone: endosteal perimeter0.00.00.00.0-0.00.10.1-0.1-0.0-0.00.00.0
Bone: final force0.40.60.90.90.70.8-0.70.70.7-0.7-0.80.9
Bone: final moment0.30.51.21.10.70.7-0.70.60.8-0.1-0.70.8
Bone: marrow area0.51.01.3-1.1-1.0-1.01.1-1.1-1.1-0.11.0-1.0
Bone: maximum diameter0.20.41.11.00.50.5-0.50.40.81.0-0.50.3
Bone: maximum force0.10.21.3-0.00.10.2-0.10.1-0.1-1.2-0.20.4
Bone: maximum moment0.00.00.30.10.00.1-0.00.0-0.0-0.6-0.10.2
Bone: minimum diameter0.20.40.80.90.50.7-0.50.50.70.2-0.70.6
Bone: periosteal estimation0.00.10.30.50.10.2-0.10.10.40.5-0.20.1
Bone: periosteal perimeter0.50.91.51.20.91.0-0.90.91.0-0.4-1.01.0
Bone: post-yield work0.10.10.7-0.3-0.00.2-0.0-0.0-0.2-0.9-0.20.2
Bone: stiffness0.00.10.4-0.2-0.10.00.1-0.1-0.2-0.60.00.1
Bone: tissue strength0.10.10.1-0.1-0.3-0.40.2-0.2-0.30.20.4-0.3
Bone: trabecular number0.50.81.2-1.1-0.9-0.70.9-0.9-1.1-0.90.7-0.6
Bone: trabecular spacing0.60.81.41.20.70.7-0.90.91.11.2-0.70.5
Bone: trabecular thickness0.81.01.7-1.3-0.9-0.91.0-1.0-1.2-0.70.9-0.7
Bone: trabecular tissue density0.60.96.80.5-0.3-0.40.3-0.30.32.60.3-0.8
Breakpoint value in progressive ratio session0.00.00.10.2-0.2-0.10.1-0.10.10.10.2-0.2
Distance traveled before self-admin0.10.10.30.60.20.4-0.20.20.50.4-0.40.3
Distance traveled after self-admin3.74.15.12.02.12.1-2.22.22.20.3-2.12.0
Delta time in closed arm before/after self-admin0.30.31.70.00.20.5-0.40.40.1-1.3-0.50.5
Delta time in open arm before/after self-admin0.60.62.4-0.5-0.6-0.60.7-0.7-0.41.50.6-0.7
Diff in mean of infusions in LGA sessions0.40.41.11.00.50.6-0.60.60.9-0.0-0.60.4
Extinction: sum of active levers before priming0.00.00.00.1-0.00.1-0.00.00.10.2-0.00.0
Active lever presses in extinction session 60.10.10.40.70.10.0-0.20.20.50.6-0.0-0.0
Delta distance traveled before/after self-admin4.75.06.91.92.62.3-2.62.62.2-0.5-2.32.4
Delta ambulatory time before/after self-admin3.84.25.71.72.32.1-2.42.42.1-0.4-2.02.2
Time in closed arm before self-admin0.20.20.7-0.8-0.3-0.40.4-0.4-0.7-0.60.2-0.2
Time in closed arm after self-admin0.40.42.4-0.80.00.10.1-0.1-0.4-1.6-0.20.2
Time in open arm before self-admin2.62.84.82.21.51.7-1.81.82.0-0.0-1.61.5
Time in open arm after self-admin0.70.82.01.20.50.7-0.70.71.11.4-0.60.5
Sum of active levers in priming session hrs 5-61.11.13.2-0.2-0.9-1.00.9-0.9-0.41.80.9-1.3
Time to tail flick, vehicle, before self-admin0.30.30.5-0.4-0.7-0.40.6-0.6-0.5-0.60.3-0.4
Time to tail flick, vehicle, after self-admin2.62.74.3-2.1-1.5-1.71.4-1.4-2.0-1.61.7-1.3
Time to tail flick, test, before self-admin5.04.96.3-1.6-2.4-2.32.2-2.2-1.92.22.4-2.5
Time to tail flick, test, after self-admin0.50.51.1-0.6-0.7-0.90.6-0.6-0.8-0.11.1-0.7
Delta time to tail flick, vehicle, before/after SA0.60.51.0-1.0-0.5-0.90.6-0.6-0.9-0.31.0-0.6
Delta time to tail flick, test, before/after SA2.01.87.80.31.21.1-1.21.20.5-2.8-0.91.4
Ambulatory time before self-admin0.10.10.60.3-0.2-0.10.3-0.30.10.80.2-0.2
Ambulatory time after self-admin3.33.74.52.02.12.0-2.12.12.10.1-1.92.0
Total heroin consumption0.10.10.50.20.20.4-0.20.20.3-0.7-0.30.3
Area under the delay curve7.98.411.6-2.4-3.1-3.22.9-3.0-2.72.03.4-3.2
Delay disc. indifference point, 0s delay1.51.62.8-1.1-1.2-1.31.0-1.1-1.01.71.5-1.5
Delay disc. indifference point, 16s delay11.011.213.5-3.0-3.6-3.63.5-3.5-3.31.73.7-3.7
Delay disc. indifference point, 2s delay3.13.45.4-1.5-1.8-2.11.7-1.7-1.61.82.3-2.1
Delay disc. indifference point, 24s delay1.21.21.8-1.2-1.2-1.20.9-1.0-1.2-0.11.3-1.1
Delay disc. indifference point, 4s delay3.23.45.8-0.8-1.8-1.91.8-1.8-1.22.42.2-2.2
Delay disc. indifference point, 8s delay5.05.27.1-1.8-2.4-2.42.3-2.3-2.01.82.7-2.5
Delay discount exponential model param7.78.111.62.43.03.1-2.92.92.7-1.9-3.43.1
Delay discount hyperbolic model param6.97.410.72.22.83.0-2.72.82.5-2.0-3.33.0
Fecal boli incidents, locomotor time 10.60.72.60.0-0.7-0.70.8-0.8-0.31.60.5-0.8
Change in fecal boli incidents, locomotor task0.10.10.20.0-0.3-0.30.2-0.2-0.00.40.3-0.4
Time >=10cm from walls, locomotor time 10.40.40.70.80.50.6-0.40.40.80.7-0.60.4
Bouts of movement, locomotor time 10.10.10.5-0.7-0.20.00.3-0.3-0.40.2-0.0-0.0
Total resting periods, locomotor time 10.10.10.3-0.10.30.6-0.20.20.20.0-0.50.5
Rest time, locomotor task time 10.70.81.0-0.7-0.9-0.81.0-1.0-0.71.00.8-1.0
Distance moved, locomotor task time 10.00.00.20.10.10.1-0.30.30.0-0.40.00.2
Vertical activity count, locomotor time 10.60.61.2-0.7-0.8-1.00.6-0.6-0.90.01.1-0.8
Time >=10cm from walls, locomotor time 20.60.61.31.10.70.8-0.50.51.01.0-0.60.5
Bouts of movement, locomotor time 20.40.40.60.50.70.7-0.50.50.6-0.8-0.60.6
Total resting periods, locomotor time 20.20.20.90.10.40.4-0.20.20.2-1.0-0.30.3
Rest time, locomotor task time 20.60.71.2-1.1-0.8-0.81.0-1.0-1.0-0.40.8-0.7
Distance moved, locomotor task time 20.91.11.41.01.01.2-1.11.11.10.3-1.11.1
Vertical activity count, locomotor time 20.10.20.4-0.1-0.4-0.40.2-0.2-0.20.60.5-0.5
Weight adjusted by age0.20.20.30.60.40.4-0.40.40.6-0.2-0.20.4
Seeking ratio, delayed vs. immediate footshock2.02.23.0-1.7-1.6-1.51.7-1.6-1.7-0.01.5-1.5
Locomotion in novel chamber0.70.91.2-0.8-1.1-1.01.0-1.0-0.90.61.0-1.0
Locomotion in novel chamber post-restriction1.41.63.5-0.5-1.3-1.31.3-1.2-0.81.91.1-1.5
Progressive ratio0.60.71.0-0.7-0.8-1.00.8-0.8-0.9-0.51.0-0.7
Food seeking constrained by brief footshock0.10.10.40.00.30.2-0.30.20.1-0.6-0.10.3
Seeking ratio, punishment vs. effort0.50.70.90.70.90.9-0.90.90.90.4-0.90.8
Run reversals in cocaine runway, females0.60.61.41.20.60.7-0.90.81.0-0.1-0.70.7
Run reversals in cocaine runway, males0.10.10.30.30.10.3-0.10.10.40.6-0.40.1
Latency to leave start box in cocaine runway1.92.12.91.71.41.6-1.41.41.60.5-1.61.4
Latency to leave start box in cocaine runway, F0.20.20.40.40.50.6-0.40.40.40.3-0.60.5
Latency to leave start box in cocaine runway, M4.74.56.92.62.12.2-2.12.12.50.2-2.32.0
Cd content in liver1.21.32.8-0.8-1.1-1.01.1-1.1-0.81.71.1-1.3
Co content in liver0.00.00.20.10.20.2-0.20.20.20.4-0.20.1
Cu content in liver0.70.93.0-0.3-0.9-0.90.8-0.8-0.51.71.0-1.1
Fe content in liver0.40.50.7-0.6-0.8-0.70.9-0.9-0.8-0.50.6-0.6
K content in liver0.90.93.2-1.4-0.6-0.60.6-0.6-1.1-1.80.6-0.2
Mg content in liver1.81.92.5-1.4-1.4-1.51.5-1.5-1.6-0.11.5-1.3
Mn content in liver0.70.81.20.51.11.0-1.01.01.0-0.1-1.01.0
Na content in liver0.10.10.20.40.20.1-0.20.20.2-0.5-0.10.3
Rb content in liver6.07.68.8-2.6-3.0-3.03.0-3.0-2.90.82.9-2.9
Se content in liver0.20.20.90.50.40.4-0.30.30.60.9-0.30.2
Sr content in liver0.80.71.01.00.90.8-0.90.91.00.6-0.90.7
Zn content in liver4.85.37.4-1.5-2.3-2.42.4-2.4-1.92.72.2-2.6