Hub : Genes

Slc22a8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000018086 0.09 0.05 6.2e-06 0.07 0.06 0.07 0.07 1.0e-06 1.8e-06 4.8e-07 7.1e-07
2 Brain mRNA stability ENSRNOG00000018086 0.07 0.04 4.2e-05 0 0.05 0.04 0.04 1.5e-01 3.1e-05 1.4e-04 1.9e-04
3 Liver gene expression ENSRNOG00000018086 0.13 0.07 2.9e-09 0.04 0.06 0.04 0.06 4.8e-05 1.9e-07 3.2e-05 5.5e-07
4 Liver isoform ratio ENSRNOT00000024488 0.06 0.04 1.8e-04 0.02 0.02 0.01 0.02 1.5e-03 1.8e-03 2.0e-02 1.8e-03
5 Liver isoform ratio ENSRNOT00000100942 0.06 0.04 2.3e-04 0.02 0.02 0.02 0.02 1.4e-03 2.2e-03 4.7e-03 2.0e-03
6 Liver mRNA stability ENSRNOG00000018086 0.06 0.03 1.6e-05 0 0.02 0.02 0.01 7.6e-02 1.1e-03 2.8e-03 1.7e-02
7 NAcc mRNA stability ENSRNOG00000018086 0.06 0.04 2.1e-03 0.03 0.03 0.01 0.01 3.6e-03 5.4e-03 2.6e-02 3.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.06.617.5-4.2-2.2-2.3-0.10.1-4.1-1.4
BMI without tail0.81.73.7-1.9-0.5-1.8-0.70.7-1.9-0.1
Body weight1.66.918.4-3.8-2.3-2.8-0.30.3-4.31.3
Epididymis fat weight0.30.63.6-0.90.2-0.1-0.10.1-0.2-1.9
Glucose0.81.36.30.30.80.80.1-0.11.1-2.5
Heart weight0.91.32.3-0.41.5-0.9-1.41.40.4-1.2
Left kidney weight0.20.40.7-0.6-0.80.30.7-0.7-0.6-0.6
Right kidney weight0.51.42.5-0.9-1.60.81.5-1.5-1.0-0.6
Tail length0.51.46.8-0.1-0.1-1.2-0.70.7-0.72.6
Length with tail0.82.96.4-1.7-1.5-1.6-0.00.0-2.42.5
Length without tail0.81.74.3-1.6-1.5-1.00.4-0.4-2.11.2
Liver weight, left0.20.30.80.50.9-0.2-0.60.60.6-0.5
Liver weight, right0.40.71.2-1.00.4-1.1-0.90.9-0.7-0.8
Parametrial fat weight0.71.37.6-0.10.20.90.6-0.60.5-2.8
Retroperitoneal fat weight0.82.511.30.11.70.5-0.70.71.4-3.4
Intraocular pressure0.40.61.11.0-0.21.10.6-0.60.80.7
Extensor digitorum longus weight2.59.926.6-4.1-3.5-2.90.2-0.2-5.22.4
Soleus weight0.92.55.21.32.20.7-0.90.92.3-2.0
Tibialis anterior weight3.211.126.4-3.5-4.3-2.21.3-1.3-5.13.5
Tibia length1.95.312.1-1.1-3.51.43.0-3.0-1.90.3
Number of licking bursts0.00.00.0-0.1-0.00.00.1-0.1-0.0-0.1
Food consumed during 24 hour testing period0.20.20.50.5-0.40.70.6-0.60.3-0.2
Times rat made contact with spout0.50.61.10.10.7-0.8-0.90.90.11.0
Mean time between licks in bursts2.02.85.9-0.81.2-2.4-2.22.2-0.81.3
Mean num. licks in bursts0.20.30.40.40.7-0.3-0.60.60.40.6
Std. dev. time between licks in bursts1.41.73.40.11.7-1.5-1.91.90.30.5
Water consumed over 24 hours0.30.31.4-0.0-0.0-0.6-0.40.4-0.31.2
Indifference point 0 sec0.20.40.9-0.9-0.6-0.6-0.10.1-1.00.2
Indifference point AUC2.22.65.6-0.2-2.41.02.1-2.1-1.21.2
Indifference point function ln k4.46.212.7-0.13.6-2.0-3.33.31.4-1.7
Indifference point function log k4.46.212.7-0.13.6-2.0-3.33.31.4-1.7
Delay discounting total patch changes 0 sec0.30.41.0-0.7-0.1-1.0-0.60.6-0.80.6
Delay discounting total patch changes 12 sec2.23.06.6-1.2-2.6-0.41.3-1.3-2.32.0
Delay discounting total patch changes 18 sec0.40.61.20.1-1.10.50.9-0.9-0.40.8
Delay discounting total patch changes 24 sec2.73.48.6-2.4-2.2-1.40.5-0.5-2.91.4
Delay discounting total patch changes 6 sec0.50.72.0-1.2-0.8-1.0-0.10.1-1.40.3
Delay discounting time to switch 0 sec0.91.32.4-1.3-1.60.31.1-1.1-1.3-1.1
Delay discounting water rate 0 sec0.40.71.50.71.2-0.3-0.90.91.00.2
Delay discounting water rate 12 sec2.53.78.60.92.9-1.3-2.52.51.50.1
Delay discounting water rate 18 sec2.83.77.7-0.42.3-2.1-2.82.80.4-0.5
Delay discounting water rate 24 sec1.21.63.90.72.0-0.6-1.61.61.2-0.3
Delay discounting water rate 6 sec1.92.86.40.62.5-1.3-2.22.21.20.0
Locomotor activity1.72.85.70.82.4-1.2-2.22.21.20.4
Locomotor testing distance2.64.28.50.32.9-1.9-2.92.91.00.1
Locomotor testing rearing1.32.14.70.52.2-1.0-1.91.91.1-0.0
Light reinforcement 10.20.30.80.90.50.3-0.10.10.70.6
Light reinforcement 22.22.95.30.1-1.72.12.3-2.30.0-1.4
Reaction time number correct0.50.72.0-0.60.2-1.1-0.80.8-0.61.4
Reaction time mean minus median2.33.05.90.9-2.02.12.4-2.4-0.00.4
Reaction time mean minus median AUC1.11.52.21.3-1.01.51.5-1.50.50.9
Reaction time num false alarms1.82.54.60.72.2-1.4-2.12.10.90.7
Reaction time num false alarms AUC1.82.54.50.51.9-1.7-2.12.10.51.2
Reaction time trials correct on left0.50.72.0-0.60.2-1.1-0.80.8-0.61.4
Reaction time trials on left0.50.72.3-0.50.2-1.0-0.80.8-0.61.5
Reaction time mean1.11.52.91.1-1.01.71.6-1.60.6-0.1
Reaction time mean AUC1.11.53.11.1-0.91.81.5-1.50.6-0.3
Median of all reaction times0.50.61.10.5-0.81.01.1-1.10.1-0.3
Reaction time omissions0.30.51.31.20.00.50.3-0.30.61.1
Reaction time false alarm rate0.91.32.60.61.6-1.0-1.51.50.70.1
Reaction time premature initiation rate2.63.57.7-2.1-0.4-2.8-1.51.5-2.51.4
Reaction time premature initiations3.04.39.0-1.9-0.3-3.0-1.71.7-2.52.4
Std. dev. reaction times1.62.34.41.8-0.92.11.8-1.81.00.4
Reaction time trials completed0.50.72.3-0.50.2-1.0-0.80.8-0.61.5
Reaction time trials AUC0.50.71.7-0.60.3-1.1-0.90.9-0.51.3
Social response proportion0.10.10.2-0.20.0-0.5-0.40.4-0.30.4
Social responses0.30.41.70.60.5-0.4-0.50.50.31.3
Social time0.40.51.30.70.8-0.4-0.70.70.61.1
Conditioned locomotion0.20.30.6-0.7-0.4-0.6-0.10.1-0.80.4
Cocaine response after cond. corrected1.51.63.1-0.11.8-1.1-1.71.70.6-1.0
Cocaine response after cond. not corrected0.91.01.8-0.11.3-0.8-1.31.30.4-0.8
Cocaine response before conditioning0.81.01.70.3-1.31.01.3-1.3-0.30.8
Saline control response1.01.32.3-1.2-0.5-1.5-0.70.7-1.51.5
Condit. Reinf. active minus inactive responses0.81.12.40.8-0.61.51.3-1.30.7-0.5
Condit. Reinf. active-inactive response ratio2.42.64.70.3-1.32.22.1-2.10.4-1.6
Condit. Reinf. active responses0.10.10.20.2-0.30.40.5-0.50.10.2
Condit. Reinf. inactive responses1.01.22.10.01.1-1.4-1.41.4-0.11.2
Condit. Reinf. lever presses0.60.92.2-0.6-1.50.21.0-1.0-1.10.3
Condit. Reinf. lever reinforcers received0.20.30.50.2-0.70.50.7-0.7-0.10.4
Pavlov. Cond. lever latency0.40.51.10.91.10.1-0.50.51.00.2
Pavlov. Cond. magazine entry latency1.41.73.5-0.8-1.9-0.40.8-0.8-1.81.7
Pavlov. Cond. change in total contacts1.52.15.3-0.5-2.30.91.8-1.8-1.30.4
Pavlov. Cond. index score1.52.05.2-0.9-2.30.21.4-1.4-1.80.7
Pavlov. Cond. latency score1.51.94.9-1.0-2.20.21.4-1.4-1.70.5
Pavlov. Cond. lever contacts0.30.30.9-0.1-0.90.30.7-0.7-0.50.5
Pavlov. Cond. magazine entry number2.73.37.91.32.80.3-1.41.42.6-1.8
Pavlov. Cond. intertrial magazine entries0.70.92.51.20.91.10.3-0.31.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.51.95.1-0.9-2.30.11.3-1.3-1.80.9
Pavlov. Cond. response bias0.71.02.5-0.5-1.60.00.9-0.9-1.30.9
Conditioned reinforcement - actives2.12.14.41.4-0.22.11.5-1.51.4-1.3
Conditioned reinforcement - inactives1.31.43.30.1-0.61.51.4-1.40.4-1.8
Conditioned locomotion0.91.15.60.20.41.00.4-0.40.8-2.4
Intermittent access intake day 1-15 change2.52.55.21.9-0.42.31.7-1.71.60.0
Intermittent access intake escalation1.81.83.71.6-0.41.91.5-1.51.20.1
Intermittent access intake escalation 21.61.63.11.0-1.11.71.7-1.70.50.4
Intermitt. access day 1 inactive lever presses0.70.82.50.50.51.00.4-0.41.1-1.6
Intermitt. access day 15 inactive lever presses1.21.41.9-1.0-1.40.71.3-1.3-0.9-1.4
Intermitt. access escalation Index1.21.12.2-0.41.1-1.2-1.51.5-0.0-0.7
Intermittent access day 1 total infusions2.02.313.2-1.5-0.0-0.2-0.00.0-0.6-3.6
Intermittent access day 15 total infusions2.12.48.80.6-0.11.81.3-1.31.1-3.0
Intermittent access terminal intake (last 3 days)2.32.57.9-0.6-1.21.41.7-1.7-0.2-2.8
Intermittent access total infusions1.61.88.5-0.6-0.61.01.0-1.0-0.1-2.9
Intermittent access day 1 locomotion2.52.610.3-2.00.1-1.1-0.80.8-1.2-3.2
Intermittent access day 15 total locomotion1.21.25.3-0.7-0.80.60.9-0.9-0.5-2.3
Intermittent access total locomotion3.13.514.1-1.9-1.40.41.2-1.2-1.4-3.8
Intermittent access standard deviation1.41.53.11.70.11.81.1-1.11.5-0.4
Cocaine induced anxiety0.50.51.2-0.3-1.10.51.0-1.0-0.5-0.0
Post-drug Anxiety1.11.22.4-0.2-1.50.91.5-1.5-0.60.7
Baseline Anxiety0.50.62.6-0.5-0.3-0.7-0.30.3-0.71.6
Lifetime Intake0.91.06.6-0.60.00.40.3-0.3-0.0-2.6
Incentive Sensitization - Responses0.80.81.3-0.6-1.10.61.1-1.1-0.7-0.9
Incentive Sensitization - Breakpoint0.90.91.3-0.6-1.10.71.2-1.2-0.6-1.0
Progressive ratio test 1 active lever presses0.90.92.10.90.61.10.3-0.31.2-1.5
Progressive ratio test 1 breakpoint1.01.02.11.00.71.20.4-0.41.4-1.4
Progressive ratio test 1 inactive lever presses0.40.40.7-0.80.3-0.8-0.70.7-0.5-0.4
Progressive ratio test 2 active lever presses1.41.55.40.4-0.21.41.1-1.10.7-2.3
Progressive ratio test 2 breakpoint1.71.94.71.00.11.81.1-1.11.3-2.2
Progressive ratio test 2 inactive lever presses1.21.45.5-0.4-0.61.11.2-1.20.1-2.3
Total sessions with >9 infusions1.11.25.7-0.21.0-0.2-0.80.80.4-2.4
Short access day 1 total inactive lever presses0.70.83.9-0.50.8-0.3-0.70.70.1-2.0
Short access day 10 total inactive lever presses1.71.84.20.72.1-0.4-1.61.61.4-1.2
Short access day 1 total infusions0.80.83.5-0.40.9-0.4-0.80.80.2-1.9
Short access day 10 total infusions1.21.36.2-1.40.0-0.5-0.30.3-0.8-2.5
Short access total infusions0.91.03.8-1.00.7-0.7-0.80.8-0.3-1.9
Short access day 1 locomotion1.41.54.0-1.7-0.0-1.1-0.70.7-1.2-2.0
Short access day 10 total locomotion0.91.03.9-1.3-0.3-0.6-0.20.2-1.0-2.0
Short access total locomotion1.71.84.5-1.9-0.3-1.2-0.60.6-1.5-2.1
Compulsive drug intake3.23.26.1-0.21.2-2.2-2.22.2-0.42.5
One hour access (0.3 mA shock)1.82.19.30.70.51.50.7-0.71.3-3.0
One hour access (shock baseline)4.14.810.31.3-0.33.02.2-2.21.8-3.2
Number of responses in last shaping day0.60.61.4-0.10.9-1.0-1.21.20.00.1
Context. condit. distance diff. score0.70.81.6-0.70.9-0.8-1.11.10.0-1.3
Locomotion velocity, session 11.01.12.1-0.61.0-1.3-1.51.5-0.2-0.3
Locomotion distance, session 11.01.32.6-1.60.1-1.6-1.11.1-1.2-0.3
Locomotion velocity, session 21.01.23.1-1.5-1.1-1.00.1-0.1-1.80.8
Locomotion distance, session 20.40.51.3-0.60.4-1.1-0.90.9-0.50.4
Locomotion velocity, session 31.41.64.5-2.1-0.2-1.3-0.70.7-1.4-1.4
Locomotion distance, session 30.40.40.8-0.60.4-0.9-0.80.8-0.4-0.1
Stereotopy head waving bouts, day 31.01.24.6-1.70.1-0.7-0.30.3-0.8-2.1
Stereotopy head waving duration, day 30.50.62.1-1.10.4-0.6-0.50.5-0.3-1.4
Locomotion velocity, session 70.30.31.3-0.8-0.2-0.10.1-0.1-0.4-1.2
Locomotion distance, session 70.70.91.3-0.90.9-1.1-1.11.1-0.3-0.8
Stereotopy head waving bouts, day 70.70.81.5-0.6-1.20.81.2-1.2-0.5-0.7
Stereotopy head waving duration, day 71.01.22.9-1.2-1.7-0.10.8-0.8-1.50.3
Locomotion velocity, session 80.81.02.00.11.3-1.0-1.41.40.40.3
Locomotion distance, session 80.40.72.1-1.00.4-0.6-0.60.6-0.3-1.5
Degree of sensitization distance0.60.61.8-1.3-0.0-0.5-0.20.2-0.7-1.4
Degree of sensitization stereotypy1.11.22.9-0.5-1.70.71.4-1.4-0.90.2
Condit. Reinf. active minus inactive responses0.40.41.0-0.7-0.9-0.30.3-0.3-1.00.6
Condit. Reinf. active-inactive response ratio0.10.20.90.0-0.2-0.3-0.10.1-0.20.9
Condit. Reinf. active responses0.91.02.4-1.0-1.60.21.1-1.1-1.3-0.1
Condit. Reinf. inactive responses0.91.11.7-0.6-1.20.81.3-1.3-0.7-1.2
Incentive salience index mean0.70.92.3-1.3-1.1-0.70.2-0.2-1.50.1
Condit. Reinf. lever presses0.60.82.2-1.5-1.0-0.60.2-0.2-1.5-0.3
Time in familiar zone, hab. session 10.20.20.4-0.6-0.2-0.5-0.20.2-0.6-0.1
Time in novel zone, hab. session 10.90.92.10.91.40.0-0.90.91.3-0.4
Total zone transitions, hab. session 10.10.10.2-0.2-0.2-0.3-0.10.1-0.40.4
Total locomotion distance, hab. session 10.20.31.2-0.6-0.30.20.5-0.5-0.3-1.1
Locomotion velocity, hab. session 10.20.30.4-0.6-0.60.10.6-0.6-0.6-0.4
Time in familiar zone, hab. session 21.01.01.80.91.3-0.5-1.11.10.81.0
Time in novel zone, hab. session 20.60.61.6-1.3-0.9-0.30.3-0.3-1.1-0.8
Total zone transitions, hab. session 21.11.42.9-1.7-0.4-1.7-0.80.8-1.70.3
Total locomotion distance, hab. session 20.40.61.3-1.2-0.0-1.0-0.50.5-0.9-0.6
Locomotion velocity, hab. session 20.30.41.2-1.1-0.2-0.6-0.20.2-0.8-0.8
Novel to familiar place preference ratio1.31.43.4-1.0-1.80.21.2-1.2-1.50.5
Novelty place preference1.01.02.5-0.8-1.60.31.1-1.1-1.10.3
Time in novel zone, NPP test0.90.92.2-0.9-1.50.10.9-0.9-1.20.3
Total zone transitions, NPP test0.50.81.5-1.1-0.4-1.2-0.60.6-1.20.5
Total locomotion distance, NPP test0.30.40.9-0.80.3-0.9-0.70.7-0.5-0.4
Locomotion velocity, NPP test0.10.20.4-0.40.3-0.6-0.50.5-0.2-0.2
Pavlov. Cond. lever latency0.91.23.01.51.40.5-0.50.51.70.3
Pavlov. Cond. magazine entry latency1.21.63.6-1.2-1.90.31.3-1.3-1.5-0.3
Pavlov. Cond. change in total contacts1.61.73.2-0.5-1.81.11.8-1.8-0.8-0.7
Pavlov. Cond. index score0.60.82.0-0.6-1.40.41.1-1.1-1.00.1
Pavlov. Cond. latency score0.40.61.3-0.8-1.10.00.7-0.7-1.0-0.1
Pavlov. Cond. lever contacts0.30.30.8-0.8-0.7-0.20.3-0.3-0.9-0.3
Pavlov. Cond. magazine entry number1.01.32.70.01.6-0.9-1.51.50.7-0.5
Pavlov. Cond. intertrial magazine entries0.60.81.40.9-0.71.21.1-1.10.40.4
Pavlov. Cond. lever-magazine prob. diff.0.91.12.6-0.6-1.60.51.3-1.3-1.10.1
Pavlov. Cond. response bias0.91.12.5-0.5-1.60.51.3-1.3-1.00.2
Bone: apparent density0.50.81.9-1.4-1.0-0.30.3-0.3-1.2-0.8
Bone surface1.73.06.9-2.0-2.60.11.6-1.6-2.3-0.5
Bone volume1.42.35.1-1.6-2.30.51.6-1.6-1.7-0.9
Bone: connectivity density1.11.74.4-2.0-1.6-0.90.3-0.3-2.1-0.3
Bone: cortical apparent density0.20.31.60.4-0.2-0.20.0-0.0-0.11.3
Bone: cortical area0.71.12.4-1.1-1.50.21.1-1.1-1.30.1
Bone: cortical porosity0.20.20.70.80.10.50.3-0.30.60.4
Bone: cortical porosity0.20.20.60.70.10.20.1-0.10.40.8
Bone: cortical thickness1.01.67.0-0.5-0.6-1.3-0.40.4-1.32.6
Bone: cortical thickness0.70.81.6-0.00.6-1.2-1.01.0-0.31.3
Bone: cortical tissue density0.20.31.90.4-0.2-0.20.0-0.0-0.11.4
Bone: elastic displacement0.91.12.21.01.5-0.4-1.11.11.10.6
Bone: elastic work0.91.22.5-0.60.5-1.6-1.31.3-0.71.1
Bone: endosteal estimation1.12.412.9-1.4-0.50.80.8-0.8-0.3-3.6
Bone: endosteal perimeter1.93.914.2-0.9-1.01.91.9-1.90.1-3.8
Bone: final force1.21.94.8-2.0-1.9-0.60.7-0.7-2.20.1
Bone: final moment1.11.94.6-1.9-1.9-0.60.7-0.7-2.10.1
Bone: marrow area1.12.413.1-1.3-0.30.80.8-0.8-0.2-3.6
Bone: maximum diameter0.91.72.9-1.0-1.70.91.6-1.6-0.9-1.0
Bone: maximum force2.44.19.0-2.9-2.7-0.51.3-1.3-3.0-0.8
Bone: maximum moment2.23.88.3-2.8-2.6-0.61.2-1.2-2.9-0.7
Bone: minimum diameter1.12.18.7-1.5-0.80.71.1-1.1-0.6-2.9
Bone: periosteal estimation1.12.34.9-1.6-1.50.81.5-1.5-1.1-2.2
Bone: periosteal perimeter0.91.52.6-0.8-1.41.01.6-1.6-0.6-1.3
Bone: post-yield work2.94.010.0-1.7-2.01.32.0-2.0-1.2-3.2
Bone: stiffness1.21.84.0-1.2-2.00.51.6-1.6-1.4-0.4
Bone: tissue strength0.10.10.20.40.30.1-0.20.20.40.1
Bone: trabecular number0.91.43.0-1.7-1.5-0.30.6-0.6-1.6-0.9
Bone: trabecular spacing1.11.42.51.21.6-0.5-1.21.21.11.1
Bone: trabecular thickness0.60.71.30.1-0.71.11.1-1.10.2-0.9
Bone: trabecular tissue density2.12.98.12.42.01.3-0.40.42.8-0.5
Breakpoint value in progressive ratio session1.11.22.40.1-1.60.41.2-1.2-0.81.5
Distance traveled before self-admin1.41.53.8-0.8-2.00.31.3-1.3-1.40.6
Distance traveled after self-admin0.40.50.80.2-0.90.60.9-0.9-0.30.7
Delta time in closed arm before/after self-admin3.63.57.9-1.61.0-2.8-2.32.3-1.30.5
Delta time in open arm before/after self-admin2.12.04.3-0.4-2.11.01.9-1.9-0.90.6
Diff in mean of infusions in LGA sessions0.80.84.70.2-0.8-0.20.4-0.4-0.52.2
Extinction: sum of active levers before priming1.51.63.2-1.1-1.8-0.40.9-0.9-1.71.4
Active lever presses in extinction session 61.91.84.1-0.1-2.00.71.6-1.6-1.01.3
Delta distance traveled before/after self-admin0.60.61.50.61.2-0.3-0.90.90.90.3
Delta ambulatory time before/after self-admin1.01.12.60.91.6-0.4-1.21.21.20.2
Time in closed arm before self-admin0.80.91.80.1-1.11.11.3-1.3-0.1-0.6
Time in closed arm after self-admin0.60.71.10.01.1-0.6-1.01.00.4-0.9
Time in open arm before self-admin3.73.97.60.42.7-1.8-2.82.81.00.2
Time in open arm after self-admin0.30.41.60.60.4-0.1-0.30.30.41.3
Sum of active levers in priming session hrs 5-63.83.77.00.8-2.32.02.6-2.6-0.21.5
Time to tail flick, vehicle, before self-admin1.11.12.3-1.5-1.2-0.20.6-0.6-1.4-1.3
Time to tail flick, vehicle, after self-admin0.91.02.1-1.20.2-1.4-1.01.0-1.0-0.5
Time to tail flick, test, before self-admin2.01.93.8-1.90.2-1.7-1.21.2-1.4-1.4
Time to tail flick, test, after self-admin0.00.00.10.30.20.20.0-0.00.4-0.1
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.00.7-0.8-0.90.90.00.2
Delta time to tail flick, test, before/after SA1.81.62.91.7-0.31.51.1-1.11.21.7
Ambulatory time before self-admin2.12.25.3-0.5-2.30.91.9-1.9-1.20.6
Ambulatory time after self-admin0.80.81.7-0.2-1.30.81.3-1.3-0.6-0.2
Total heroin consumption1.21.45.9-0.1-1.4-0.30.7-0.7-1.12.4
Area under the delay curve0.40.40.7-0.80.3-0.8-0.70.7-0.5-0.6
Delay disc. indifference point, 0s delay1.31.41.9-1.21.1-1.3-1.41.4-0.3-1.3
Delay disc. indifference point, 16s delay0.40.40.7-0.8-0.7-0.10.4-0.4-0.7-0.8
Delay disc. indifference point, 2s delay0.30.31.8-0.60.1-0.1-0.10.1-0.2-1.3
Delay disc. indifference point, 24s delay0.70.61.4-0.50.6-1.2-1.11.1-0.40.2
Delay disc. indifference point, 4s delay1.41.53.2-1.30.7-1.8-1.51.5-0.9-0.1
Delay disc. indifference point, 8s delay0.80.81.7-0.01.3-0.9-1.31.30.4-0.2
Delay discount exponential model param0.40.40.70.8-0.40.80.7-0.70.40.6
Delay discount hyperbolic model param0.40.50.80.9-0.30.90.7-0.70.50.6
Fecal boli incidents, locomotor time 11.71.83.40.6-1.21.91.8-1.80.4-0.8
Change in fecal boli incidents, locomotor task2.22.14.0-0.31.9-1.5-2.02.00.4-0.5
Time >=10cm from walls, locomotor time 12.22.26.20.4-0.61.91.5-1.50.7-2.5
Bouts of movement, locomotor time 11.61.86.01.6-0.31.20.9-0.91.02.4
Total resting periods, locomotor time 11.31.54.01.3-0.61.21.1-1.10.72.0
Rest time, locomotor task time 10.70.72.01.30.80.90.0-0.01.4-0.2
Distance moved, locomotor task time 10.20.20.6-0.7-0.4-0.5-0.10.1-0.8-0.3
Vertical activity count, locomotor time 10.20.20.70.30.60.1-0.30.30.6-0.8
Time >=10cm from walls, locomotor time 21.11.22.50.9-0.81.61.4-1.40.6-0.1
Bouts of movement, locomotor time 20.50.52.2-0.4-0.7-0.40.2-0.2-0.81.5
Total resting periods, locomotor time 20.30.31.2-0.3-0.6-0.20.2-0.2-0.51.1
Rest time, locomotor task time 21.11.33.01.11.40.8-0.30.31.7-1.4
Distance moved, locomotor task time 20.30.31.60.4-0.50.10.3-0.3-0.21.3
Vertical activity count, locomotor time 20.80.91.70.81.1-0.5-1.01.00.71.3
Weight adjusted by age1.11.22.8-1.1-1.7-0.01.0-1.0-1.50.4
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.30.1-0.4-0.40.4-0.30.0
Locomotion in novel chamber1.72.15.30.6-0.41.91.4-1.40.9-2.3
Locomotion in novel chamber post-restriction1.01.22.91.30.91.20.4-0.41.7-1.2
Progressive ratio0.30.40.6-0.5-0.80.30.7-0.7-0.5-0.7
Food seeking constrained by brief footshock0.40.51.10.01.0-0.7-1.01.00.30.3
Seeking ratio, punishment vs. effort1.11.42.80.21.5-1.1-1.71.70.50.6
Run reversals in cocaine runway, females3.23.16.5-2.00.7-2.6-2.02.0-1.6-0.5
Run reversals in cocaine runway, males0.30.30.90.70.80.3-0.30.30.9-0.0
Latency to leave start box in cocaine runway0.40.53.0-0.50.00.00.1-0.1-0.2-1.7
Latency to leave start box in cocaine runway, F0.10.10.3-0.3-0.30.00.3-0.3-0.3-0.5
Latency to leave start box in cocaine runway, M1.00.93.10.71.10.6-0.10.11.2-1.8
Cd content in liver0.60.61.30.70.21.10.5-0.51.1-1.0
Co content in liver3.13.67.42.12.7-0.4-1.91.92.31.0
Cu content in liver0.40.50.9-0.10.5-0.9-1.01.0-0.20.8
Fe content in liver0.10.20.30.0-0.40.50.5-0.50.1-0.3
K content in liver1.11.12.6-1.5-1.3-0.40.6-0.6-1.6-0.4
Mg content in liver1.01.02.8-1.7-0.9-0.50.2-0.2-1.4-1.0
Mn content in liver1.11.23.2-1.0-1.8-0.01.0-1.0-1.50.7
Na content in liver0.70.81.7-0.7-1.30.31.0-1.0-0.9-0.0
Rb content in liver0.81.02.00.01.4-0.4-1.11.10.8-1.2
Se content in liver1.72.13.9-0.5-2.01.42.0-2.0-0.7-0.6
Sr content in liver1.91.73.5-0.9-1.9-0.40.9-0.9-1.71.7
Zn content in liver1.82.04.5-1.5-2.1-0.51.0-1.0-2.10.8