Dnajb13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000017975 0.15 0.1 3.2e-06 0.04 0.1 0.1 0.09 3.1e-03 3.1e-06 3.1e-06 1.0e-05
2 BLA intron excision ratio chr1:154850574:154862890 0.12 0.08 9.8e-06 0.09 0.1 0.08 0.09 1.8e-05 6.1e-06 3.0e-05 1.9e-05
3 BLA mRNA stability ENSRNOG00000017975 0.14 0.09 2.8e-06 0.11 0.12 0.11 0.11 1.2e-06 8.0e-07 1.2e-06 1.7e-06
4 Brain gene expression ENSRNOG00000017975 0.03 0.03 1.0e-02 0.02 0.01 0.02 0.01 7.2e-03 5.8e-02 1.2e-02 1.8e-02
5 Brain intron excision ratio chr1:154850574:154862890 0.33 0.16 0.0e+00 0.33 0.33 0.32 0.32 2.8e-31 2.0e-31 9.9e-31 7.0e-31
6 Brain intron excision ratio chr1:154851183:154852870 0.07 0.05 4.9e-06 0.07 0.06 0.06 0.07 6.5e-07 2.1e-06 8.0e-06 9.0e-07
7 Brain intron excision ratio chr1:154852983:154862890 0.07 0.05 1.9e-05 0.05 0.06 0.06 0.05 1.6e-05 7.1e-06 4.7e-06 1.1e-05
8 Brain intron excision ratio chr1:154857476:154858820 0.04 0.03 3.4e-03 0.02 0.03 0.03 0.02 9.0e-03 1.2e-03 1.0e-03 2.4e-03
9 Brain mRNA stability ENSRNOG00000017975 0.1 0.07 1.1e-07 0.08 0.08 0.08 0.08 1.1e-07 6.1e-08 1.1e-07 1.5e-07
10 IL gene expression ENSRNOG00000017975 0.34 0.17 5.2e-05 0.06 0.11 0.08 0.09 1.6e-02 1.5e-03 6.1e-03 4.2e-03
11 IL intron excision ratio chr1:154850574:154862890 0.22 0.14 2.9e-03 0.01 0.02 -0.01 -0 1.4e-01 1.0e-01 6.3e-01 3.8e-01
12 IL intron excision ratio chr1:154852983:154857315 0.29 0.17 1.5e-03 0.03 0.09 0.08 0.06 6.4e-02 4.2e-03 5.8e-03 1.8e-02
13 NAcc gene expression ENSRNOG00000017975 0.13 0.08 5.6e-09 0.11 0.09 0.1 0.11 1.2e-08 3.9e-07 7.1e-08 1.2e-08
14 NAcc intron excision ratio chr1:154850574:154851070 0.04 0.04 9.1e-03 0.03 0 0.01 0.02 2.5e-03 1.5e-01 3.9e-02 1.9e-02
15 NAcc intron excision ratio chr1:154850574:154862890 0.09 0.06 1.8e-06 0.07 0.08 0.06 0.09 3.6e-06 1.3e-06 1.6e-05 4.6e-07
16 NAcc intron excision ratio chr1:154852983:154862890 0.07 0.05 1.9e-03 0.03 0.02 0.03 0.02 2.8e-03 1.2e-02 4.4e-03 1.7e-02
17 OFC gene expression ENSRNOG00000017975 0.23 0.14 3.3e-04 0.1 0.08 0.1 0.08 2.3e-03 6.8e-03 2.0e-03 5.5e-03
18 OFC intron excision ratio chr1:154850574:154862890 0.21 0.13 6.7e-04 0.1 0.1 0.07 0.09 2.1e-03 2.9e-03 7.8e-03 3.8e-03
19 OFC mRNA stability ENSRNOG00000017975 0.19 0.13 1.5e-03 0.11 0.11 0.14 0.14 1.4e-03 1.4e-03 3.9e-04 3.3e-04
20 PL gene expression ENSRNOG00000017975 0.4 0.19 0.0e+00 0.34 0.31 0.35 0.33 1.3e-26 2.1e-24 2.7e-27 5.3e-26
21 PL intron excision ratio chr1:154850574:154862890 0.23 0.12 5.6e-17 0.19 0.19 0.2 0.2 2.1e-14 2.3e-14 2.9e-15 1.5e-15
22 PL intron excision ratio chr1:154852983:154862890 0.04 0.03 5.8e-03 0.04 0.01 0.02 0.02 7.2e-04 2.3e-02 1.9e-02 5.9e-03
23 PL mRNA stability ENSRNOG00000017975 0.19 0.11 3.5e-13 0.09 0.13 0.16 0.08 2.6e-07 3.1e-10 3.7e-12 6.5e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
BMI with tail0.10.20.6-0.3-0.5-0.40.1-0.50.50.70.7-0.2-0.6-0.4-0.2-0.6-0.0-0.60.7-0.5-0.5-0.4-0.5-0.60.0-0.3
BMI without tail0.91.86.7-0.1-1.2-0.81.4-1.11.21.82.30.3-1.9-0.5-2.1-1.3-1.3-1.22.6-1.3-1.4-1.0-0.9-1.20.0-0.0
Body weight0.73.09.9-0.4-1.6-1.31.4-1.51.72.53.00.0-2.4-0.8-2.2-1.8-1.2-1.83.1-1.8-1.8-1.4-1.4-1.70.0-0.4
Epididymis fat weight1.53.56.2-1.5-2.1-1.9-0.0-2.12.12.52.5-1.2-2.3-1.7-0.6-2.20.3-2.12.1-2.1-2.1-2.1-2.1-2.10.0-1.5
Glucose0.10.10.20.20.40.30.00.4-0.4-0.5-0.50.20.40.30.20.4-0.10.4-0.40.40.40.40.30.40.00.2
Heart weight1.01.52.31.51.31.41.51.3-1.3-0.7-0.31.51.01.5-1.01.3-1.41.20.51.31.21.41.31.20.01.5
Left kidney weight0.51.68.20.7-0.4-0.12.3-0.30.41.32.11.1-1.30.3-2.5-0.6-2.0-0.42.9-0.5-0.5-0.2-0.2-0.60.00.8
Right kidney weight0.31.05.40.4-0.5-0.21.8-0.40.31.11.70.7-1.10.1-1.9-0.5-1.5-0.42.3-0.5-0.5-0.2-0.3-0.70.00.4
Tail length1.64.721.80.8-1.3-0.63.2-1.11.42.73.81.4-2.70.1-4.3-1.4-3.0-1.34.7-1.4-1.6-1.0-0.7-1.50.00.8
Length with tail1.13.915.40.0-1.6-1.12.0-1.51.92.83.50.6-2.7-0.5-3.2-1.8-1.9-1.83.9-1.8-1.8-1.4-1.1-1.80.00.1
Length without tail0.10.30.6-0.6-0.5-0.5-0.8-0.50.60.40.2-0.7-0.3-0.60.6-0.50.7-0.6-0.2-0.5-0.4-0.5-0.5-0.40.0-0.6
Liver weight, left1.62.64.3-1.3-1.9-1.7-0.4-1.81.92.12.0-1.1-2.0-1.5-0.5-1.90.3-1.91.4-1.9-1.8-1.8-1.7-1.90.0-1.3
Liver weight, right3.65.99.4-2.1-2.8-2.6-0.6-2.82.93.12.9-1.7-3.1-2.4-0.6-2.90.6-2.82.2-2.9-2.9-2.8-2.7-2.80.0-2.0
Parametrial fat weight1.63.14.9-1.7-2.0-1.9-0.7-2.02.22.11.8-1.5-2.0-1.80.0-2.21.0-2.11.2-2.0-2.0-2.0-1.9-1.90.0-1.6
Retroperitoneal fat weight6.321.032.5-4.1-5.3-5.0-1.5-5.25.45.75.3-3.5-5.5-4.6-0.6-5.31.7-5.63.6-5.3-5.3-5.2-5.1-5.30.0-4.0
Intraocular pressure0.50.81.50.71.00.90.10.9-1.0-1.2-1.20.61.10.80.31.1-0.21.1-0.91.01.01.00.90.90.00.6
Extensor digitorum longus weight0.41.63.2-0.9-1.4-1.30.1-1.41.41.71.8-0.7-1.7-1.1-0.7-1.4-0.1-1.51.6-1.4-1.5-1.3-1.4-1.40.0-0.9
Soleus weight1.13.27.5-1.0-2.0-1.70.4-1.92.02.52.7-0.7-2.5-1.4-1.4-2.0-0.4-2.12.5-2.0-2.0-1.8-1.8-2.00.0-1.0
Tibialis anterior weight0.10.41.60.0-0.4-0.30.7-0.40.40.81.10.2-0.8-0.1-1.0-0.4-0.7-0.51.3-0.5-0.5-0.4-0.4-0.50.00.1
Tibia length2.26.28.62.72.82.81.92.8-2.8-2.6-2.02.52.62.8-0.82.8-1.82.8-0.92.82.72.82.92.80.02.7
Number of licking bursts4.95.88.3-2.9-2.6-2.8-2.2-2.72.62.11.3-2.8-2.2-2.91.6-2.52.3-2.60.1-2.6-2.6-2.7-2.9-2.60.0-2.9
Food consumed during 24 hour testing period3.84.66.32.52.32.42.02.4-2.3-1.9-1.22.51.92.5-1.32.4-2.12.4-0.12.32.32.42.52.30.02.5
Times rat made contact with spout0.91.01.6-0.8-1.1-1.1-0.2-1.11.21.31.2-0.7-1.3-1.0-0.3-1.10.2-1.20.9-1.2-1.2-1.1-1.1-1.20.0-0.8
Mean time between licks in bursts2.23.113.22.00.51.03.30.6-0.30.92.02.4-0.71.5-3.60.4-3.20.23.30.40.30.71.00.30.02.0
Mean num. licks in bursts3.74.46.62.62.32.42.12.3-2.2-1.7-1.02.61.82.5-1.62.2-2.22.20.22.22.22.32.52.20.02.6
Std. dev. time between licks in bursts1.11.36.30.5-0.5-0.21.7-0.50.71.42.00.8-1.30.2-2.2-0.5-1.7-0.62.5-0.6-0.7-0.4-0.3-0.70.00.5
Water consumed over 24 hours0.30.41.0-0.8-0.4-0.5-1.0-0.50.40.0-0.3-0.9-0.1-0.71.0-0.30.9-0.3-0.7-0.4-0.4-0.5-0.6-0.40.0-0.8
Indifference point 0 sec3.04.98.02.82.32.52.82.3-2.2-1.4-0.52.81.62.6-2.12.2-2.72.21.02.22.22.32.42.20.02.7
Indifference point AUC0.50.61.4-0.3-0.8-0.60.6-0.70.91.01.1-0.1-1.1-0.5-0.8-0.8-0.6-0.71.2-0.8-0.9-0.7-0.6-0.80.0-0.2
Indifference point function ln k2.33.25.01.72.12.00.82.1-2.2-2.2-1.91.52.11.80.12.1-0.72.2-1.22.12.12.12.02.10.01.6
Indifference point function log k2.33.25.01.72.12.00.82.1-2.2-2.2-1.91.52.11.80.12.1-0.72.2-1.22.12.12.12.02.10.01.6
Delay discounting total patch changes 0 sec2.33.76.32.41.92.12.52.0-1.9-1.1-0.32.51.32.3-1.91.9-2.41.91.01.91.92.02.01.80.02.3
Delay discounting total patch changes 12 sec0.50.73.30.80.10.31.70.1-0.00.51.01.1-0.50.6-1.80.0-1.70.21.70.0-0.00.20.2-0.00.00.8
Delay discounting total patch changes 18 sec1.21.54.51.61.01.22.01.1-0.7-0.30.31.70.41.4-1.80.9-2.10.91.20.90.91.01.21.00.01.6
Delay discounting total patch changes 24 sec0.50.63.00.80.10.31.40.20.10.61.11.0-0.50.6-1.70.0-1.4-0.01.60.00.10.10.40.00.00.9
Delay discounting total patch changes 6 sec0.50.71.31.00.90.91.10.9-0.9-0.7-0.41.00.61.0-0.70.8-1.01.00.30.80.80.90.80.80.00.9
Delay discounting time to switch 0 sec2.23.47.3-2.4-1.7-1.9-2.7-1.81.70.9-0.0-2.5-0.9-2.22.3-1.72.6-1.6-1.4-1.7-1.5-1.8-2.0-1.60.0-2.4
Delay discounting water rate 0 sec2.43.96.22.52.02.22.42.1-2.1-1.4-0.62.51.52.4-1.82.0-2.32.00.62.01.92.12.21.90.02.4
Delay discounting water rate 12 sec2.13.24.72.22.02.11.52.0-1.9-1.5-1.02.11.62.1-1.21.9-1.51.8-0.12.01.92.02.22.00.02.1
Delay discounting water rate 18 sec0.81.02.21.40.91.01.30.9-0.9-0.40.11.50.41.2-1.50.9-1.30.70.70.90.81.01.10.80.01.4
Delay discounting water rate 24 sec1.92.64.21.61.91.80.81.8-1.9-2.0-1.81.41.81.7-0.11.9-0.62.0-1.11.81.81.81.81.80.01.5
Delay discounting water rate 6 sec1.31.92.91.61.51.61.01.6-1.5-1.4-1.11.51.31.6-0.71.5-1.11.5-0.41.51.51.51.71.50.01.5
Locomotor activity0.50.81.41.01.01.01.20.9-1.2-0.9-0.51.00.81.0-0.61.0-0.91.20.21.00.81.10.90.90.01.0
Locomotor testing distance1.11.94.71.71.21.42.21.3-1.4-0.60.11.90.61.6-1.81.1-2.01.31.21.21.11.41.31.10.01.7
Locomotor testing rearing0.30.52.70.5-0.20.01.4-0.10.10.71.20.7-0.70.3-1.5-0.3-1.2-0.11.6-0.2-0.3-0.0-0.0-0.30.00.5
Light reinforcement 12.03.66.0-2.4-1.9-2.1-2.2-2.02.01.30.7-2.4-1.3-2.31.9-2.02.3-1.9-0.4-1.8-1.8-2.0-2.2-1.80.0-2.5
Light reinforcement 20.20.21.2-0.40.0-0.1-0.8-0.0-0.0-0.3-0.6-0.60.4-0.31.10.20.80.0-0.90.10.1-0.0-0.20.10.0-0.5
Reaction time number correct0.91.33.70.61.21.0-0.41.1-1.5-1.8-1.90.31.50.81.01.30.51.4-1.81.21.11.21.01.10.00.5
Reaction time mean minus median0.30.41.50.80.40.61.20.4-0.20.00.40.90.00.7-1.20.3-1.10.41.00.40.40.50.60.40.00.8
Reaction time mean minus median AUC0.81.01.71.31.11.21.21.1-0.9-0.8-0.41.30.81.2-0.90.9-1.11.10.31.11.11.11.21.10.01.3
Reaction time num false alarms2.23.04.5-2.0-1.9-2.0-1.4-2.01.71.61.1-1.9-1.6-2.01.0-1.91.6-1.90.3-1.9-1.9-1.9-2.1-1.90.0-2.1
Reaction time num false alarms AUC1.01.42.2-1.4-1.3-1.3-1.1-1.31.11.00.7-1.4-1.0-1.40.9-1.31.2-1.30.1-1.2-1.2-1.3-1.4-1.30.0-1.5
Reaction time trials correct on left0.91.33.70.61.21.0-0.41.1-1.5-1.8-1.90.31.50.81.01.30.51.4-1.81.21.11.21.01.10.00.5
Reaction time trials on left0.91.33.70.51.21.0-0.41.1-1.5-1.8-1.90.31.50.81.01.30.51.4-1.81.21.11.21.01.10.00.5
Reaction time mean1.01.42.0-1.3-1.3-1.3-0.8-1.31.41.21.0-1.2-1.2-1.30.3-1.30.8-1.40.5-1.3-1.3-1.3-1.4-1.30.0-1.3
Reaction time mean AUC1.11.42.1-1.4-1.3-1.3-1.1-1.31.41.10.8-1.3-1.1-1.40.7-1.31.2-1.40.1-1.3-1.2-1.3-1.3-1.20.0-1.4
Median of all reaction times1.41.92.6-1.6-1.5-1.6-1.3-1.51.51.30.9-1.6-1.2-1.60.9-1.41.3-1.60.1-1.5-1.4-1.5-1.6-1.40.0-1.6
Reaction time omissions0.40.60.9-0.8-0.9-0.9-0.4-0.90.90.90.8-0.8-0.8-0.90.2-0.80.5-0.90.5-0.9-0.9-0.8-0.9-0.90.0-0.8
Reaction time false alarm rate1.92.63.7-1.7-1.8-1.8-1.0-1.81.81.81.5-1.6-1.7-1.80.4-1.91.0-1.90.9-1.8-1.8-1.8-1.9-1.80.0-1.7
Reaction time premature initiation rate1.01.36.60.7-0.4-0.11.9-0.30.61.31.91.0-1.20.3-2.4-0.6-1.9-0.62.6-0.5-0.4-0.3-0.1-0.50.00.7
Reaction time premature initiations0.50.72.71.10.40.61.60.5-0.40.10.61.2-0.10.9-1.60.3-1.50.41.20.40.40.60.60.30.01.0
Std. dev. reaction times0.50.72.5-0.1-0.7-0.50.8-0.70.81.11.40.1-1.1-0.3-1.2-0.8-0.8-0.81.6-0.8-0.8-0.6-0.6-0.80.0-0.1
Reaction time trials completed0.91.33.70.51.21.0-0.41.1-1.5-1.8-1.90.31.50.81.01.30.51.4-1.81.21.11.21.01.10.00.5
Reaction time trials AUC0.71.02.80.51.00.8-0.31.0-1.3-1.6-1.70.31.30.70.81.10.41.3-1.51.10.91.10.81.00.00.4
Social response proportion0.60.71.4-0.7-1.0-0.9-0.4-1.01.00.90.8-0.6-1.0-0.8-0.2-1.20.4-1.00.5-1.0-1.0-1.0-0.9-1.00.0-0.7
Social responses1.31.62.9-0.9-1.4-1.3-0.1-1.41.61.71.7-0.7-1.7-1.1-0.6-1.60.1-1.51.4-1.5-1.4-1.5-1.3-1.40.0-0.9
Social time1.52.05.6-1.8-1.1-1.4-2.4-1.21.20.4-0.4-2.0-0.4-1.62.1-1.32.4-1.2-1.5-1.1-1.0-1.3-1.2-1.00.0-1.8
Conditioned locomotion0.10.10.4-0.10.20.1-0.40.2-0.2-0.4-0.5-0.20.40.00.60.20.40.2-0.60.20.20.20.20.20.0-0.1
Cocaine response after cond. corrected2.42.63.6-1.8-1.8-1.8-1.2-1.81.81.71.3-1.7-1.7-1.80.6-1.91.3-1.90.6-1.8-1.8-1.8-1.8-1.80.0-1.7
Cocaine response after cond. not corrected0.60.61.0-0.9-0.9-0.9-0.7-0.90.90.80.7-0.8-0.8-0.90.4-0.90.7-1.00.3-0.9-0.9-0.9-0.9-0.90.0-0.9
Cocaine response before conditioning2.53.14.21.92.02.01.22.0-2.0-1.9-1.51.71.92.0-0.42.1-1.22.0-0.72.02.02.02.02.00.01.8
Saline control response1.01.33.81.50.81.01.90.9-0.7-0.10.61.70.21.3-1.90.8-1.90.71.40.80.70.91.10.70.01.5
Condit. Reinf. active minus inactive responses3.94.813.12.91.72.13.51.8-1.6-0.50.63.20.62.5-3.41.6-3.61.72.21.61.51.92.21.50.02.9
Condit. Reinf. active-inactive response ratio1.21.22.51.41.01.21.51.1-0.9-0.5-0.01.50.61.3-1.41.0-1.61.00.71.01.01.11.21.00.01.5
Condit. Reinf. active responses4.66.419.03.31.82.34.32.0-1.6-0.31.03.70.42.9-4.31.7-4.41.82.81.71.62.02.41.60.03.3
Condit. Reinf. inactive responses2.43.010.02.21.11.43.11.2-0.90.01.12.50.01.9-3.20.9-3.11.02.31.00.91.21.40.90.02.2
Condit. Reinf. lever presses11.015.131.95.13.64.15.53.7-3.4-1.8-0.15.42.04.7-5.03.4-5.63.52.53.43.33.84.33.30.05.1
Condit. Reinf. lever reinforcers received5.57.721.23.62.22.74.52.3-2.0-0.60.84.00.73.2-4.42.0-4.62.12.82.01.92.42.71.90.03.7
Pavlov. Cond. lever latency11.716.031.2-5.2-3.8-4.3-5.5-4.03.62.20.4-5.4-2.3-4.84.8-3.65.6-3.7-2.2-3.7-3.6-4.0-4.4-3.60.0-5.2
Pavlov. Cond. magazine entry latency3.64.26.42.52.22.32.22.2-2.1-1.6-0.92.51.62.4-1.72.1-2.22.10.32.12.12.22.42.10.02.5
Pavlov. Cond. change in total contacts9.813.723.74.73.74.14.73.8-3.5-2.3-0.84.92.44.4-4.03.5-4.93.61.53.53.53.84.23.50.04.7
Pavlov. Cond. index score9.612.522.44.53.53.84.73.6-3.3-2.0-0.64.72.24.3-4.03.3-4.73.41.73.33.23.64.03.20.04.6
Pavlov. Cond. latency score8.711.019.44.33.33.64.33.4-3.1-2.0-0.64.42.14.0-3.73.1-4.43.21.43.13.13.43.83.10.04.3
Pavlov. Cond. lever contacts12.217.032.95.33.94.45.64.1-3.7-2.2-0.45.62.35.0-4.93.7-5.73.92.23.83.74.24.63.70.05.4
Pavlov. Cond. magazine entry number6.37.711.8-3.4-2.9-3.1-3.1-3.02.82.11.2-3.4-2.2-3.32.3-2.83.1-2.9-0.4-2.9-2.8-3.0-3.3-2.80.0-3.4
Pavlov. Cond. intertrial magazine entries0.81.02.9-0.4-1.0-0.90.5-1.01.11.51.7-0.2-1.4-0.6-1.0-1.0-0.5-1.21.7-1.1-1.1-1.0-0.9-1.10.0-0.4
Pavlov. Cond. lever-magazine prob. diff.8.711.321.24.33.23.64.53.4-3.1-1.8-0.44.52.04.1-3.93.1-4.63.11.83.13.03.43.83.00.04.4
Pavlov. Cond. response bias12.917.732.35.44.14.65.64.2-3.9-2.4-0.75.62.65.1-4.83.9-5.74.02.03.93.94.34.73.90.05.5
Conditioned reinforcement - actives3.43.34.62.12.12.11.72.1-2.1-1.6-1.12.01.82.1-0.92.0-1.62.0-0.12.12.22.12.12.00.02.0
Conditioned reinforcement - inactives0.30.30.8-0.4-0.6-0.5-0.3-0.50.70.90.8-0.3-0.6-0.5-0.1-0.70.2-0.90.5-0.5-0.3-0.6-0.5-0.50.0-0.4
Conditioned locomotion3.84.57.22.22.42.41.42.4-2.6-2.2-1.82.12.32.3-0.62.7-1.52.4-0.82.42.12.52.52.40.02.3
Intermittent access intake day 1-15 change0.70.71.10.90.80.90.80.8-1.0-0.9-0.60.90.60.9-0.61.0-0.81.1-0.10.90.80.90.80.70.00.9
Intermittent access intake escalation0.80.81.51.00.91.00.90.9-1.1-1.1-0.81.00.71.0-0.61.2-0.81.2-0.21.00.91.10.90.80.00.9
Intermittent access intake escalation 20.10.10.50.2-0.00.00.7-0.0-0.2-0.10.10.3-0.30.1-0.70.1-0.50.30.4-0.0-0.20.1-0.1-0.20.00.2
Intermitt. access day 1 inactive lever presses0.50.51.0-0.6-0.8-0.8-0.6-0.80.91.00.8-0.6-0.8-0.70.0-0.90.3-1.00.4-0.7-0.5-0.9-0.7-0.80.0-0.7
Intermitt. access day 15 inactive lever presses0.30.30.80.60.70.70.20.7-0.5-0.4-0.50.50.80.60.10.6-0.30.5-0.30.70.90.60.80.80.00.7
Intermitt. access escalation Index0.30.30.70.60.50.50.80.5-0.5-0.4-0.20.60.30.6-0.50.5-0.50.70.20.50.50.50.50.40.00.6
Intermittent access day 1 total infusions0.91.02.11.41.01.11.21.1-0.6-0.20.21.40.61.3-1.20.9-1.40.50.70.91.00.91.31.00.01.4
Intermittent access day 15 total infusions1.71.92.91.71.51.61.41.5-1.3-1.0-0.61.71.11.6-1.11.6-1.41.40.21.41.51.51.71.40.01.7
Intermittent access terminal intake (last 3 days)1.31.42.31.51.21.31.51.2-1.1-0.7-0.21.50.81.4-1.21.3-1.51.10.51.11.11.21.31.10.01.5
Intermittent access total infusions0.91.01.91.31.01.11.11.0-0.7-0.3-0.01.40.61.2-1.10.9-1.40.60.50.91.00.91.21.00.01.4
Intermittent access day 1 locomotion0.30.30.60.50.60.60.10.6-0.5-0.5-0.40.50.70.60.00.7-0.30.4-0.30.50.50.60.70.70.00.6
Intermittent access day 15 total locomotion1.51.62.51.41.41.51.21.4-1.4-1.2-0.91.41.21.5-0.71.6-1.11.5-0.11.31.11.51.51.40.01.5
Intermittent access total locomotion0.70.71.41.11.01.00.91.0-0.7-0.5-0.31.10.81.1-0.61.0-1.00.70.20.80.70.91.11.00.01.2
Intermittent access standard deviation0.10.10.30.1-0.1-0.00.4-0.10.10.20.40.2-0.30.0-0.4-0.1-0.6-0.00.5-0.1-0.1-0.1-0.2-0.20.00.1
Cocaine induced anxiety1.61.83.4-1.8-1.3-1.5-1.5-1.41.20.80.3-1.8-0.8-1.61.5-1.31.9-1.2-0.5-1.3-1.3-1.4-1.6-1.30.0-1.8
Post-drug Anxiety1.21.31.7-1.3-1.3-1.3-0.8-1.31.21.00.8-1.2-1.1-1.30.5-1.31.2-1.20.2-1.3-1.3-1.3-1.3-1.30.0-1.2
Baseline Anxiety0.60.61.91.10.60.71.10.6-0.5-0.10.31.20.10.9-1.40.6-1.40.50.70.50.50.60.90.50.01.1
Lifetime Intake1.21.32.61.61.21.31.21.2-0.9-0.4-0.11.60.81.4-1.21.0-1.50.70.51.11.21.11.51.20.01.6
Incentive Sensitization - Responses1.21.24.91.30.81.02.20.8-0.9-0.20.41.50.21.2-1.70.7-1.90.91.30.70.50.90.90.60.01.4
Incentive Sensitization - Breakpoint1.21.24.41.30.91.02.10.9-1.0-0.40.21.50.31.2-1.60.8-1.81.01.10.80.61.01.00.70.01.4
Progressive ratio test 1 active lever presses0.10.10.2-0.2-0.1-0.2-0.5-0.10.30.30.2-0.2-0.1-0.20.2-0.10.3-0.4-0.1-0.2-0.1-0.3-0.1-0.10.0-0.1
Progressive ratio test 1 breakpoint0.10.10.3-0.2-0.3-0.3-0.4-0.30.40.50.4-0.2-0.2-0.20.0-0.30.2-0.50.1-0.3-0.2-0.4-0.2-0.20.0-0.2
Progressive ratio test 1 inactive lever presses0.30.30.60.70.50.60.50.50.10.40.50.70.30.6-0.70.1-0.6-0.30.70.40.60.30.70.60.00.8
Progressive ratio test 2 active lever presses0.50.62.20.90.60.71.50.6-0.5-0.00.41.00.20.8-1.10.4-1.30.51.00.50.40.60.70.50.01.0
Progressive ratio test 2 breakpoint0.50.62.40.90.60.71.50.6-0.50.00.41.10.10.8-1.20.4-1.30.51.10.40.40.60.70.50.01.0
Progressive ratio test 2 inactive lever presses1.01.11.91.31.21.31.11.3-0.9-0.6-0.31.21.11.3-0.61.0-1.00.80.31.11.21.11.41.30.01.4
Total sessions with >9 infusions2.83.15.32.22.02.11.42.0-1.6-1.2-0.82.11.62.2-1.21.8-1.61.50.01.92.01.92.32.00.02.3
Short access day 1 total inactive lever presses0.10.10.5-0.00.0-0.0-0.70.00.50.30.0-0.10.1-0.00.3-0.40.5-0.4-0.3-0.00.2-0.20.20.10.0-0.0
Short access day 10 total inactive lever presses0.10.10.2-0.3-0.1-0.1-0.4-0.1-0.1-0.3-0.4-0.30.0-0.20.4-0.20.40.1-0.40.0-0.0-0.1-0.2-0.10.0-0.3
Short access day 1 total infusions1.81.93.71.81.31.51.81.4-1.1-0.50.01.90.81.7-1.71.1-1.80.90.91.21.31.31.61.30.01.9
Short access day 10 total infusions0.80.92.71.30.70.91.50.8-0.50.10.61.40.21.1-1.60.5-1.60.41.10.60.60.61.00.70.01.4
Short access total infusions0.70.81.91.30.81.01.10.9-0.40.00.41.30.41.1-1.30.5-1.30.20.70.70.90.71.20.80.01.4
Short access day 1 locomotion2.72.94.51.92.02.01.02.0-1.9-1.6-1.31.71.91.9-0.42.0-1.01.8-0.51.91.92.02.12.10.01.9
Short access day 10 total locomotion0.20.21.10.40.20.31.10.2-0.5-0.20.10.5-0.00.4-0.70.4-0.80.50.70.2-0.00.40.10.10.00.5
Short access total locomotion0.20.20.30.50.40.50.50.5-0.4-0.2-0.10.50.40.5-0.30.6-0.40.30.20.30.20.50.50.40.00.5
Compulsive drug intake0.30.30.80.10.50.4-0.20.5-0.7-0.8-0.9-0.10.80.20.80.40.50.6-0.70.70.70.50.30.50.00.0
One hour access (0.3 mA shock)1.51.83.61.71.31.41.71.3-1.2-0.7-0.21.80.81.6-1.61.2-1.91.20.61.21.31.41.51.20.01.7
One hour access (shock baseline)1.01.13.31.40.91.11.50.9-0.8-0.40.11.50.41.3-1.61.0-1.80.90.70.80.71.01.10.80.01.4
Number of responses in last shaping day0.20.21.00.3-0.10.00.9-0.00.10.50.70.4-0.30.2-0.8-0.2-0.7-0.11.0-0.2-0.3-0.10.0-0.10.00.4
Context. condit. distance diff. score2.73.24.52.12.02.11.52.1-2.0-1.7-1.22.01.82.1-0.92.0-1.52.0-0.32.02.02.02.11.90.02.0
Locomotion velocity, session 10.30.31.4-0.10.40.2-0.70.4-0.4-0.8-1.0-0.30.70.11.00.40.70.4-1.20.40.40.30.20.40.0-0.1
Locomotion distance, session 11.11.41.81.21.31.30.81.3-1.4-1.3-1.11.11.31.3-0.31.4-0.81.4-0.51.31.31.41.31.30.01.2
Locomotion velocity, session 20.00.00.10.20.10.20.30.1-0.1-0.00.10.30.00.2-0.30.1-0.30.10.20.10.10.10.20.10.00.3
Locomotion distance, session 20.40.60.90.90.90.90.70.9-0.9-0.8-0.60.80.80.9-0.40.9-0.70.9-0.20.90.90.90.80.80.00.8
Locomotion velocity, session 31.11.31.91.11.31.30.61.3-1.4-1.4-1.21.01.31.20.01.4-0.61.4-0.81.31.21.41.31.40.01.1
Locomotion distance, session 32.12.33.21.51.71.70.81.7-1.8-1.8-1.51.31.71.6-0.11.8-0.81.8-0.91.71.71.81.71.80.01.4
Stereotopy head waving bouts, day 30.60.81.1-0.8-1.0-1.0-0.4-1.01.01.01.0-0.7-1.0-0.9-0.0-1.00.4-1.00.6-1.0-1.0-1.0-0.9-1.00.0-0.8
Stereotopy head waving duration, day 30.10.10.20.30.50.40.10.4-0.4-0.5-0.40.30.50.40.10.4-0.10.4-0.30.50.50.40.40.50.00.4
Locomotion velocity, session 70.10.10.5-0.4-0.1-0.2-0.6-0.10.1-0.1-0.4-0.50.2-0.30.7-0.10.6-0.1-0.6-0.1-0.0-0.2-0.2-0.10.0-0.4
Locomotion distance, session 70.10.20.3-0.5-0.4-0.5-0.4-0.50.40.40.2-0.5-0.4-0.50.2-0.40.4-0.40.0-0.4-0.4-0.5-0.5-0.50.0-0.5
Stereotopy head waving bouts, day 72.63.04.02.01.92.01.61.9-1.9-1.6-1.11.91.62.0-1.01.9-1.61.9-0.11.91.92.02.01.90.02.0
Stereotopy head waving duration, day 72.73.34.82.21.92.12.02.0-1.9-1.4-0.82.21.52.1-1.41.9-2.01.90.31.91.82.02.11.90.02.2
Locomotion velocity, session 80.70.91.21.11.01.10.91.0-1.0-0.8-0.51.10.81.1-0.61.0-0.91.00.01.01.01.01.11.00.01.1
Locomotion distance, session 82.13.24.62.12.02.01.82.0-1.9-1.5-1.02.11.62.1-1.21.9-1.81.90.11.91.92.02.11.80.02.1
Degree of sensitization distance2.62.64.6-1.2-1.8-1.7-0.2-1.81.92.12.1-1.0-2.1-1.5-0.7-1.90.2-1.91.7-1.8-1.8-1.8-1.7-1.90.0-1.2
Degree of sensitization stereotypy5.66.18.42.92.72.82.42.7-2.7-2.2-1.42.82.22.9-1.52.7-2.42.7-0.02.72.62.82.92.60.02.9
Condit. Reinf. active minus inactive responses0.20.21.00.2-0.3-0.10.6-0.20.30.60.80.3-0.60.0-0.9-0.3-0.6-0.31.0-0.3-0.3-0.2-0.1-0.30.00.2
Condit. Reinf. active-inactive response ratio0.30.31.60.5-0.10.11.0-0.10.20.60.90.6-0.50.3-1.3-0.1-1.0-0.21.3-0.2-0.2-0.00.1-0.20.00.5
Condit. Reinf. active responses0.10.10.3-0.1-0.3-0.20.2-0.30.30.40.5-0.0-0.4-0.2-0.4-0.3-0.2-0.30.5-0.3-0.3-0.3-0.3-0.30.0-0.1
Condit. Reinf. inactive responses0.00.00.1-0.2-0.0-0.1-0.3-0.0-0.0-0.1-0.2-0.20.1-0.10.40.00.30.0-0.3-0.0-0.0-0.0-0.10.00.0-0.2
Incentive salience index mean0.10.20.80.3-0.10.00.7-0.10.10.40.60.4-0.40.2-0.9-0.1-0.7-0.10.9-0.1-0.20.0-0.0-0.10.00.3
Condit. Reinf. lever presses0.00.10.20.30.10.20.50.1-0.10.00.20.3-0.10.2-0.40.1-0.50.10.40.10.00.20.10.10.00.3
Time in familiar zone, hab. session 10.20.10.4-0.1-0.4-0.30.1-0.40.40.60.6-0.1-0.5-0.2-0.4-0.4-0.1-0.40.6-0.4-0.4-0.4-0.3-0.40.0-0.1
Time in novel zone, hab. session 10.20.20.3-0.6-0.5-0.5-0.5-0.50.40.30.1-0.6-0.4-0.60.4-0.40.5-0.4-0.2-0.5-0.5-0.5-0.5-0.50.0-0.6
Total zone transitions, hab. session 10.30.41.10.30.70.6-0.20.7-0.7-0.9-1.10.20.90.40.60.70.20.7-1.00.70.80.70.50.70.00.3
Total locomotion distance, hab. session 11.72.43.8-1.4-1.8-1.7-0.5-1.81.81.91.8-1.1-1.9-1.5-0.3-1.80.5-1.81.3-1.8-1.8-1.7-1.9-1.90.0-1.4
Locomotion velocity, hab. session 11.01.42.2-1.0-1.4-1.3-0.3-1.31.41.41.4-0.8-1.5-1.1-0.3-1.30.3-1.41.0-1.3-1.3-1.3-1.4-1.40.0-1.1
Time in familiar zone, hab. session 20.90.92.21.30.81.01.50.9-0.7-0.30.21.40.31.1-1.40.7-1.50.70.90.80.70.91.10.70.01.3
Time in novel zone, hab. session 20.20.20.8-0.5-0.2-0.3-0.8-0.20.1-0.2-0.5-0.60.1-0.40.9-0.10.8-0.1-0.8-0.1-0.1-0.2-0.3-0.10.0-0.5
Total zone transitions, hab. session 21.82.33.01.61.71.71.11.7-1.7-1.6-1.31.51.61.7-0.41.7-1.11.7-0.51.71.71.71.71.70.01.6
Total locomotion distance, hab. session 20.71.02.6-0.4-1.0-0.80.5-1.01.11.41.6-0.2-1.4-0.6-1.0-1.1-0.5-1.11.6-1.0-1.0-0.9-0.9-1.10.0-0.4
Locomotion velocity, hab. session 21.01.43.5-0.6-1.3-1.10.4-1.21.31.71.9-0.4-1.6-0.8-1.0-1.3-0.4-1.31.7-1.3-1.3-1.2-1.1-1.30.0-0.6
Novel to familiar place preference ratio0.10.10.10.30.30.30.20.3-0.3-0.2-0.20.30.30.3-0.10.3-0.20.3-0.00.30.30.30.30.30.00.3
Novelty place preference0.10.10.10.30.30.30.20.3-0.3-0.3-0.20.30.30.3-0.10.3-0.20.3-0.00.30.30.30.30.30.00.3
Time in novel zone, NPP test0.20.20.30.50.50.50.40.5-0.5-0.4-0.30.50.40.5-0.20.5-0.40.5-0.00.50.50.50.50.50.00.5
Total zone transitions, NPP test0.40.61.00.70.90.90.30.9-1.0-1.0-0.90.61.00.80.10.9-0.31.0-0.60.90.90.90.80.90.00.7
Total locomotion distance, NPP test1.11.52.5-1.0-1.4-1.3-0.2-1.41.41.61.5-0.8-1.6-1.2-0.4-1.40.2-1.41.2-1.4-1.4-1.4-1.4-1.40.0-1.0
Locomotion velocity, NPP test1.42.03.0-1.3-1.7-1.6-0.5-1.61.71.71.6-1.1-1.7-1.5-0.1-1.70.5-1.71.1-1.6-1.6-1.6-1.7-1.70.0-1.4
Pavlov. Cond. lever latency0.81.02.2-1.3-0.9-1.1-1.5-1.00.90.4-0.0-1.4-0.5-1.21.3-0.91.5-0.9-0.8-0.9-0.8-1.0-1.0-1.00.0-1.3
Pavlov. Cond. magazine entry latency1.82.35.12.01.41.62.31.4-1.3-0.60.22.10.71.8-2.11.3-2.31.31.21.31.21.51.61.30.02.0
Pavlov. Cond. change in total contacts0.91.02.11.30.91.01.50.9-0.8-0.30.21.40.41.2-1.40.8-1.50.80.90.80.80.91.10.80.01.3
Pavlov. Cond. index score1.82.35.32.01.31.52.31.4-1.2-0.50.22.10.61.8-2.11.3-2.31.21.31.21.11.41.51.30.02.0
Pavlov. Cond. latency score1.82.35.11.91.31.62.31.4-1.2-0.60.22.10.71.8-2.01.3-2.31.21.21.21.21.41.61.30.02.0
Pavlov. Cond. lever contacts0.70.82.31.10.60.81.50.7-0.6-0.10.41.30.21.0-1.50.6-1.50.61.10.60.50.70.80.70.01.2
Pavlov. Cond. magazine entry number2.32.95.5-2.2-1.6-1.8-2.3-1.71.50.90.1-2.3-1.0-2.12.0-1.62.3-1.5-1.1-1.5-1.5-1.7-1.9-1.60.0-2.2
Pavlov. Cond. intertrial magazine entries0.60.71.7-1.1-0.7-0.9-1.3-0.80.70.3-0.2-1.2-0.3-1.01.2-0.71.3-0.7-0.8-0.7-0.7-0.8-0.9-0.70.0-1.1
Pavlov. Cond. lever-magazine prob. diff.1.51.84.21.81.21.42.01.2-1.1-0.50.21.90.61.6-1.91.1-2.01.11.11.11.11.31.41.20.01.8
Pavlov. Cond. response bias0.70.82.21.20.70.91.50.7-0.6-0.20.31.30.21.0-1.40.7-1.50.61.00.60.60.80.90.70.01.2
Bone: apparent density0.10.20.7-0.10.30.2-0.40.2-0.3-0.6-0.7-0.20.50.10.70.40.40.4-0.80.30.30.30.10.30.0-0.1
Bone surface0.50.91.61.20.91.01.21.0-0.8-0.5-0.11.30.61.1-1.00.9-1.30.90.50.90.91.01.10.90.01.2
Bone volume0.30.60.90.90.80.80.90.8-0.7-0.5-0.21.00.50.9-0.70.8-0.90.70.30.70.70.80.80.70.00.9
Bone: connectivity density0.30.51.20.40.70.6-0.20.7-0.8-1.0-1.10.20.90.50.60.90.10.8-1.00.80.80.80.60.80.00.4
Bone: cortical apparent density2.22.94.0-1.9-1.9-2.0-1.4-2.01.81.61.2-1.8-1.7-2.00.7-1.91.5-1.80.4-1.9-1.9-1.9-2.0-1.90.0-1.9
Bone: cortical area0.20.21.10.50.10.20.90.1-0.00.30.60.6-0.30.4-1.1-0.0-0.90.11.00.10.00.20.20.00.00.5
Bone: cortical porosity1.51.62.31.31.51.50.71.5-1.4-1.4-1.21.21.51.4-0.11.4-0.71.4-0.61.51.51.41.51.50.01.3
Bone: cortical porosity1.31.42.01.21.41.40.61.4-1.3-1.3-1.11.11.41.3-0.01.4-0.61.3-0.71.41.41.31.41.40.01.2
Bone: cortical thickness0.10.10.3-0.4-0.2-0.3-0.4-0.30.20.0-0.1-0.4-0.1-0.40.5-0.30.6-0.2-0.3-0.2-0.3-0.2-0.3-0.30.0-0.4
Bone: cortical thickness0.20.30.40.50.60.60.30.6-0.6-0.6-0.60.40.60.50.00.6-0.20.7-0.30.60.60.70.60.60.00.5
Bone: cortical tissue density2.12.83.8-1.9-1.9-1.9-1.4-1.91.81.51.1-1.8-1.7-1.90.8-1.91.5-1.80.3-1.9-1.9-1.9-1.9-1.90.0-1.9
Bone: elastic displacement1.11.34.0-1.5-0.8-1.0-1.9-0.80.70.0-0.6-1.6-0.1-1.32.0-0.82.0-0.7-1.5-0.7-0.6-0.9-1.0-0.60.0-1.5
Bone: elastic work0.91.24.6-1.3-0.5-0.8-2.0-0.60.4-0.3-0.9-1.50.2-1.12.1-0.62.0-0.4-1.8-0.5-0.4-0.7-0.8-0.40.0-1.3
Bone: endosteal estimation0.61.25.61.20.20.52.00.3-0.00.71.41.4-0.60.9-2.40.1-2.10.02.20.10.10.30.50.10.01.2
Bone: endosteal perimeter0.81.56.11.50.50.82.30.6-0.40.41.21.8-0.31.2-2.50.5-2.40.42.10.50.40.70.80.40.01.5
Bone: final force0.00.00.1-0.2-0.2-0.2-0.1-0.20.20.20.2-0.1-0.2-0.20.0-0.30.2-0.20.2-0.2-0.2-0.2-0.2-0.20.0-0.2
Bone: final moment0.00.00.10.1-0.0-0.00.2-0.00.00.10.20.1-0.10.0-0.2-0.1-0.1-0.00.3-0.0-0.0-0.00.0-0.00.00.1
Bone: marrow area0.51.04.91.00.00.31.80.10.10.81.51.2-0.70.7-2.2-0.0-1.9-0.12.1-0.0-0.00.10.3-0.00.01.0
Bone: maximum diameter0.81.54.91.60.81.02.20.9-0.70.10.81.80.11.3-2.20.6-2.10.71.80.70.70.91.00.70.01.6
Bone: maximum force0.00.00.10.10.00.10.30.1-0.00.10.10.2-0.00.1-0.2-0.1-0.10.00.30.00.00.10.10.00.00.1
Bone: maximum moment0.00.10.30.40.20.30.50.2-0.2-0.00.10.40.10.3-0.50.1-0.40.20.40.20.20.20.30.20.00.4
Bone: minimum diameter0.71.35.40.0-0.9-0.61.2-0.81.01.62.10.4-1.5-0.3-1.9-0.9-1.2-1.02.3-1.0-1.0-0.8-0.6-1.00.00.0
Bone: periosteal estimation0.51.04.61.10.30.51.90.3-0.10.61.21.4-0.50.8-2.10.1-1.90.11.90.20.20.40.50.20.01.1
Bone: periosteal perimeter0.61.03.71.20.50.71.80.6-0.40.20.91.4-0.11.0-1.90.5-1.80.41.60.50.40.60.70.40.01.2
Bone: post-yield work0.10.20.30.50.40.40.50.4-0.4-0.2-0.10.50.30.5-0.40.5-0.50.40.20.40.40.40.50.40.00.5
Bone: stiffness0.50.81.2-0.7-1.0-0.9-0.2-1.01.01.11.0-0.6-1.1-0.8-0.2-1.10.3-1.00.8-1.0-1.0-0.9-0.9-1.00.0-0.7
Bone: tissue strength0.80.83.10.10.80.6-0.80.7-0.8-1.3-1.6-0.11.20.31.30.80.80.8-1.80.80.80.70.60.80.00.1
Bone: trabecular number0.40.62.5-0.9-0.2-0.4-1.4-0.30.1-0.4-0.9-1.00.3-0.71.6-0.11.4-0.1-1.5-0.2-0.2-0.3-0.5-0.20.0-0.9
Bone: trabecular spacing0.70.91.41.21.01.11.11.0-0.9-0.6-0.31.20.71.1-0.80.8-1.00.90.30.91.00.91.11.00.01.2
Bone: trabecular thickness0.30.30.5-0.6-0.6-0.6-0.4-0.60.60.50.4-0.6-0.6-0.70.3-0.70.5-0.60.1-0.6-0.6-0.6-0.6-0.60.0-0.6
Bone: trabecular tissue density2.73.85.7-1.8-2.3-2.2-0.7-2.32.22.32.1-1.6-2.4-2.0-0.2-2.40.9-2.21.5-2.3-2.3-2.2-2.2-2.30.0-1.8
Breakpoint value in progressive ratio session0.20.20.9-0.30.20.1-0.60.1-0.2-0.5-0.7-0.40.5-0.10.90.30.70.2-0.80.20.20.10.10.30.0-0.2
Distance traveled before self-admin1.21.32.2-1.5-1.2-1.3-0.9-1.30.90.60.3-1.4-1.0-1.40.9-1.11.2-0.9-0.2-1.2-1.3-1.2-1.5-1.40.0-1.5
Distance traveled after self-admin0.60.63.0-0.10.50.3-1.10.5-0.6-1.1-1.4-0.31.00.11.30.80.90.6-1.70.60.70.50.40.50.0-0.2
Delta time in closed arm before/after self-admin4.54.47.3-1.8-2.4-2.3-0.3-2.42.42.62.5-1.5-2.6-2.0-0.4-2.70.5-2.41.8-2.5-2.5-2.4-2.3-2.40.0-1.7
Delta time in open arm before/after self-admin2.82.64.72.11.61.81.91.7-1.4-0.9-0.22.21.12.0-1.71.6-2.11.40.81.61.61.71.91.50.02.1
Diff in mean of infusions in LGA sessions3.13.54.8-2.2-2.0-2.1-2.0-2.02.01.40.8-2.2-1.6-2.21.3-2.12.0-2.0-0.4-2.0-2.0-2.1-2.1-2.00.0-2.2
Extinction: sum of active levers before priming0.10.10.2-0.3-0.3-0.3-0.3-0.30.40.40.3-0.3-0.3-0.30.1-0.20.1-0.40.1-0.4-0.3-0.4-0.3-0.30.0-0.3
Active lever presses in extinction session 64.84.68.11.92.42.31.12.4-2.7-2.6-2.21.72.52.10.12.9-0.92.7-1.22.52.42.52.32.30.01.9
Delta distance traveled before/after self-admin2.02.23.51.71.71.70.41.7-1.4-1.4-1.21.51.61.7-0.41.8-1.01.4-0.81.71.91.61.91.70.01.6
Delta ambulatory time before/after self-admin2.52.74.51.71.91.90.32.0-1.6-1.7-1.51.51.91.8-0.12.1-0.91.6-1.11.92.11.82.02.00.01.6
Time in closed arm before self-admin4.75.38.02.12.72.50.72.6-2.8-2.8-2.61.82.82.30.32.7-0.62.8-1.72.72.72.72.62.80.02.1
Time in closed arm after self-admin0.40.41.8-0.6-0.0-0.2-1.2-0.1-0.1-0.5-0.9-0.80.4-0.41.3-0.21.20.1-1.30.00.0-0.1-0.20.10.0-0.5
Time in open arm before self-admin4.75.07.9-2.7-2.5-2.6-1.7-2.62.21.91.2-2.6-2.1-2.71.4-2.42.0-2.20.1-2.5-2.5-2.5-2.8-2.60.0-2.8
Time in open arm after self-admin0.50.62.5-0.0-0.6-0.51.0-0.60.61.01.30.2-1.0-0.2-1.2-0.5-1.0-0.61.6-0.7-0.7-0.5-0.5-0.90.0-0.1
Sum of active levers in priming session hrs 5-60.10.10.6-0.30.1-0.0-0.30.0-0.3-0.4-0.5-0.40.3-0.10.70.40.40.3-0.50.20.10.1-0.10.00.0-0.3
Time to tail flick, vehicle, before self-admin0.10.10.2-0.10.10.1-0.30.1-0.2-0.3-0.4-0.10.30.00.40.40.20.2-0.50.10.20.10.1-0.00.0-0.1
Time to tail flick, vehicle, after self-admin2.83.05.02.12.02.11.12.0-1.6-1.4-1.02.01.72.1-0.91.8-1.51.7-0.31.92.11.92.22.00.02.0
Time to tail flick, test, before self-admin0.20.20.80.4-0.00.10.60.00.10.40.60.5-0.30.3-0.90.2-0.9-0.20.8-0.1-0.1-0.00.20.10.00.5
Time to tail flick, test, after self-admin0.60.62.20.1-0.6-0.40.8-0.50.71.11.30.3-1.0-0.1-1.4-0.7-0.9-0.71.5-0.6-0.6-0.5-0.3-0.80.00.2
Delta time to tail flick, vehicle, before/after SA1.71.73.11.71.51.61.01.5-1.0-0.8-0.41.61.21.6-0.91.2-1.21.00.11.41.61.31.81.60.01.6
Delta time to tail flick, test, before/after SA0.30.30.8-0.6-0.6-0.6-0.4-0.60.60.50.3-0.6-0.5-0.60.2-0.90.6-0.60.1-0.6-0.6-0.6-0.6-0.70.0-0.6
Ambulatory time before self-admin0.91.01.9-1.3-1.0-1.1-1.1-1.10.70.4-0.0-1.3-0.7-1.21.1-0.91.2-0.7-0.6-0.9-1.0-0.9-1.2-1.10.0-1.4
Ambulatory time after self-admin1.11.24.10.31.00.8-1.01.0-1.0-1.5-1.90.01.50.61.41.30.71.0-2.01.11.21.00.91.10.00.2
Total heroin consumption0.50.61.00.70.90.90.40.9-0.9-0.8-0.70.70.90.8-0.01.0-0.20.9-0.30.90.90.90.90.90.00.8
Area under the delay curve0.20.20.4-0.4-0.4-0.40.3-0.40.30.50.5-0.3-0.5-0.4-0.0-0.40.0-0.30.6-0.4-0.5-0.4-0.6-0.50.0-0.3
Delay disc. indifference point, 0s delay0.40.41.30.80.50.61.10.5-0.5-0.20.20.90.20.7-1.00.5-1.10.60.60.50.40.60.60.50.00.8
Delay disc. indifference point, 16s delay0.00.00.2-0.2-0.0-0.0-0.1-0.0-0.1-0.1-0.2-0.20.1-0.10.40.00.30.1-0.20.00.0-0.0-0.20.00.0-0.1
Delay disc. indifference point, 2s delay0.40.42.20.5-0.00.11.3-0.00.00.61.00.7-0.50.3-1.3-0.1-1.2-0.11.5-0.1-0.10.1-0.0-0.10.00.6
Delay disc. indifference point, 24s delay0.60.61.3-1.1-0.7-0.8-0.9-0.80.60.3-0.0-1.1-0.4-1.01.1-0.71.0-0.6-0.4-0.7-0.7-0.7-1.0-0.70.0-1.0
Delay disc. indifference point, 4s delay0.50.52.40.4-0.2-0.01.4-0.20.20.71.20.6-0.70.2-1.4-0.3-1.2-0.21.6-0.3-0.3-0.1-0.2-0.30.00.4
Delay disc. indifference point, 8s delay0.00.00.3-0.0-0.0-0.00.5-0.0-0.00.10.20.0-0.1-0.0-0.1-0.0-0.10.10.5-0.0-0.1-0.0-0.1-0.10.0-0.0
Delay discount exponential model param0.20.20.40.50.50.4-0.20.5-0.4-0.5-0.50.40.50.5-0.00.4-0.10.4-0.60.50.50.40.70.50.00.4
Delay discount hyperbolic model param0.20.20.70.30.50.4-0.50.5-0.4-0.6-0.70.20.60.30.30.40.20.4-0.90.40.50.40.60.50.00.2
Fecal boli incidents, locomotor time 11.41.52.21.21.41.40.61.4-1.5-1.4-1.21.11.41.3-0.21.5-0.61.5-0.61.41.41.51.41.40.01.2
Change in fecal boli incidents, locomotor task1.01.01.5-1.1-1.1-1.1-1.2-1.11.10.80.4-1.1-0.9-1.20.6-1.11.0-1.1-0.3-1.0-1.1-1.2-1.0-1.10.0-1.1
Time >=10cm from walls, locomotor time 12.22.23.01.71.71.71.31.7-1.7-1.4-1.01.61.51.7-0.71.7-1.11.7-0.11.71.71.71.71.70.01.6
Bouts of movement, locomotor time 10.30.30.50.50.60.60.40.6-0.7-0.6-0.50.50.50.6-0.20.7-0.50.7-0.10.60.60.70.50.60.00.5
Total resting periods, locomotor time 10.50.51.10.50.80.8-0.10.8-0.9-1.0-1.10.40.90.60.30.9-0.10.9-0.80.80.90.90.70.90.00.5
Rest time, locomotor task time 10.20.20.70.10.50.4-0.50.5-0.4-0.7-0.9-0.00.70.20.70.40.40.4-0.90.50.50.40.50.50.00.2
Distance moved, locomotor task time 10.50.61.8-0.2-0.7-0.60.8-0.70.61.01.20.0-1.0-0.4-1.0-0.7-0.7-0.61.3-0.7-0.8-0.6-0.7-0.80.0-0.3
Vertical activity count, locomotor time 10.30.31.40.2-0.2-0.10.9-0.20.30.71.00.4-0.60.1-1.0-0.3-0.7-0.31.2-0.2-0.2-0.2-0.2-0.30.00.1
Time >=10cm from walls, locomotor time 21.01.02.01.41.01.11.41.0-0.8-0.40.11.40.61.3-1.30.8-1.40.80.70.91.00.91.31.00.01.4
Bouts of movement, locomotor time 20.40.41.30.0-0.6-0.30.7-0.50.40.71.00.2-0.9-0.2-1.1-0.4-1.0-0.41.1-0.6-0.6-0.3-0.6-0.60.0-0.0
Total resting periods, locomotor time 20.40.51.0-0.3-0.8-0.60.3-0.70.70.80.9-0.1-1.0-0.4-0.8-0.7-0.6-0.70.9-0.8-0.8-0.6-0.8-0.80.0-0.3
Rest time, locomotor task time 22.12.45.2-1.9-1.4-1.6-2.3-1.41.60.90.1-2.1-0.8-1.81.9-1.52.3-1.6-1.1-1.4-1.3-1.7-1.5-1.30.0-1.9
Distance moved, locomotor task time 21.92.26.41.91.21.42.51.3-1.2-0.50.42.10.51.7-2.21.2-2.41.21.61.21.11.31.41.00.01.8
Vertical activity count, locomotor time 20.60.73.10.90.30.51.80.3-0.20.41.01.1-0.20.7-1.60.2-1.50.21.60.30.20.30.40.20.00.8
Weight adjusted by age0.30.41.60.3-0.3-0.10.9-0.20.20.71.00.5-0.70.1-1.2-0.4-1.0-0.31.3-0.3-0.2-0.2-0.2-0.40.00.2
Seeking ratio, delayed vs. immediate footshock0.60.73.2-0.9-0.4-0.6-1.8-0.50.70.1-0.5-1.10.1-0.81.5-0.21.5-0.7-1.3-0.4-0.2-0.6-0.4-0.30.0-1.0
Locomotion in novel chamber1.51.94.01.01.51.40.61.4-2.0-2.0-1.80.91.61.20.31.7-0.62.0-1.11.51.31.61.21.40.01.0
Locomotion in novel chamber post-restriction2.63.14.42.02.02.01.32.0-2.0-1.7-1.21.91.72.0-0.81.9-1.42.0-0.31.91.92.02.12.00.02.0
Progressive ratio0.20.20.40.30.50.40.00.5-0.6-0.6-0.60.20.60.30.30.5-0.00.5-0.50.60.60.50.40.40.00.2
Food seeking constrained by brief footshock0.40.52.30.60.00.21.40.1-0.20.40.90.9-0.50.5-1.50.1-1.40.11.50.0-0.10.20.2-0.10.00.7
Seeking ratio, punishment vs. effort0.60.73.10.3-0.5-0.21.2-0.40.51.01.50.6-1.00.1-1.7-0.5-1.2-0.51.8-0.6-0.7-0.3-0.2-0.50.00.4
Run reversals in cocaine runway, females4.14.18.5-1.2-2.2-2.00.1-2.12.52.92.9-0.9-2.7-1.6-1.3-2.4-0.2-2.52.4-2.3-2.2-2.2-1.9-2.20.0-1.2
Run reversals in cocaine runway, males0.00.00.1-0.1-0.0-0.0-0.3-0.00.20.1-0.1-0.20.1-0.10.4-0.20.3-0.2-0.2-0.00.0-0.1-0.00.00.0-0.1
Latency to leave start box in cocaine runway3.43.75.5-2.0-2.1-2.2-1.7-2.12.32.01.4-2.0-1.9-2.10.7-2.41.6-2.30.3-2.1-2.0-2.3-2.0-2.20.0-2.0
Latency to leave start box in cocaine runway, F3.74.16.3-2.0-2.3-2.3-1.2-2.32.52.42.0-1.8-2.3-2.10.2-2.51.1-2.51.0-2.3-2.2-2.4-2.2-2.50.0-1.9
Latency to leave start box in cocaine runway, M0.20.20.9-0.4-0.1-0.2-0.9-0.10.0-0.3-0.6-0.50.2-0.30.9-0.10.9-0.0-0.9-0.00.0-0.1-0.10.00.0-0.4
Cd content in liver1.01.11.6-1.0-1.2-1.2-0.5-1.21.21.21.1-0.9-1.3-1.1-0.0-1.20.5-1.20.7-1.2-1.3-1.2-1.3-1.20.0-1.0
Co content in liver0.70.83.21.10.40.61.70.4-0.20.30.91.3-0.20.9-1.80.2-1.60.31.50.30.40.40.60.30.01.1
Cu content in liver0.40.52.50.6-0.10.11.3-0.00.10.71.10.8-0.60.4-1.6-0.1-1.3-0.21.5-0.1-0.00.00.1-0.20.00.6
Fe content in liver0.10.10.1-0.2-0.3-0.3-0.1-0.30.40.40.3-0.2-0.3-0.3-0.1-0.40.1-0.30.3-0.3-0.2-0.3-0.3-0.30.0-0.2
K content in liver0.50.50.7-0.6-0.8-0.7-0.3-0.80.80.80.8-0.5-0.8-0.7-0.1-0.80.3-0.80.6-0.8-0.6-0.8-0.7-0.80.0-0.6
Mg content in liver0.10.10.20.30.20.20.50.2-0.10.10.20.4-0.00.3-0.50.1-0.40.10.40.10.20.20.20.10.00.4
Mn content in liver0.70.83.5-1.0-0.2-0.4-1.7-0.30.1-0.5-1.1-1.20.4-0.71.9-0.11.6-0.1-1.7-0.1-0.1-0.3-0.4-0.10.0-1.0
Na content in liver0.30.30.50.70.60.60.40.6-0.6-0.5-0.40.60.60.7-0.30.6-0.50.6-0.10.60.70.60.70.60.00.6
Rb content in liver0.40.51.51.00.60.71.20.6-0.5-0.20.21.00.30.9-1.10.5-1.10.60.70.60.60.70.80.60.01.0
Se content in liver2.12.55.6-2.1-1.4-1.7-2.4-1.51.40.7-0.1-2.2-0.7-1.92.1-1.42.4-1.4-1.3-1.4-1.1-1.6-1.7-1.40.0-2.1
Sr content in liver0.30.20.60.20.50.4-0.10.5-0.4-0.7-0.80.10.70.30.50.40.30.5-0.80.50.60.50.50.50.00.2
Zn content in liver3.33.76.72.51.92.12.61.9-1.8-1.0-0.22.61.22.3-2.21.8-2.61.71.11.81.81.92.11.70.02.5