Hub : Genes

Ucp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017854 0.11 0.07 6.9e-13 0.1 0.1 0.09 0.08 9.7e-11 1.1e-10 1.0e-09 1.3e-09
2 BLA gene expression ENSRNOG00000017854 0.34 0.15 6.1e-16 0.22 0.28 0.3 0.28 3.8e-12 1.8e-15 1.7e-16 2.8e-15
3 Brain gene expression ENSRNOG00000017854 0.47 0.19 0.0e+00 0.43 0.43 0.43 0.43 4.8e-43 1.4e-43 2.3e-43 3.6e-43
4 Eye gene expression ENSRNOG00000017854 0.73 0.15 1.7e-07 0.04 0.13 0.15 0.11 7.1e-02 5.0e-03 2.7e-03 9.6e-03
5 LHb gene expression ENSRNOG00000017854 0.19 0.13 6.6e-03 0.01 0.03 0.04 0.01 1.7e-01 6.5e-02 4.3e-02 2.0e-01
6 Liver gene expression ENSRNOG00000017854 0.04 0.03 2.0e-04 0.01 0.02 0.01 0.01 9.7e-03 2.2e-03 2.3e-02 9.6e-03
7 NAcc gene expression ENSRNOG00000017854 0.08 0.05 1.9e-05 0.04 0.06 0.07 0.05 2.7e-04 4.9e-05 7.2e-06 8.1e-05
8 PL gene expression ENSRNOG00000017854 0.09 0.06 3.5e-06 0.05 0.06 0.08 0.05 1.7e-04 1.2e-05 2.1e-06 9.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.10.20.40.60.40.50.40.00.50.60.4
BMI without tail0.30.71.91.40.51.00.20.01.10.60.5
Body weight0.31.53.31.80.91.50.50.01.61.31.0
Epididymis fat weight1.43.34.62.11.92.01.60.02.12.11.8
Glucose0.10.10.2-0.3-0.3-0.4-0.20.0-0.4-0.4-0.3
Heart weight1.21.72.3-1.2-1.4-1.3-1.40.0-1.3-1.4-1.5
Left kidney weight0.00.10.40.5-0.30.3-0.60.00.4-0.1-0.4
Right kidney weight0.00.10.30.5-0.10.3-0.30.00.4-0.1-0.1
Tail length0.20.72.41.5-0.21.0-0.80.01.20.30.0
Length with tail0.31.13.01.70.41.4-0.10.01.51.10.7
Length without tail0.10.30.70.30.60.50.60.00.50.80.7
Liver weight, left1.62.53.41.81.51.81.30.01.81.81.7
Liver weight, right3.55.97.82.82.42.82.00.02.82.72.6
Parametrial fat weight1.63.24.61.91.82.01.60.02.02.11.9
Retroperitoneal fat weight6.621.930.75.34.75.24.10.05.25.55.0
Intraocular pressure0.50.71.2-1.0-0.8-0.9-0.60.0-1.0-1.1-0.9
Extensor digitorum longus weight0.41.52.21.51.21.41.00.01.41.31.2
Soleus weight0.92.54.32.11.41.91.10.01.91.81.5
Tibialis anterior weight0.00.10.20.50.10.40.00.00.40.30.2
Tibia length2.67.29.3-2.7-2.9-2.9-2.70.0-2.8-3.1-3.0
Number of licking bursts5.97.09.02.63.02.72.90.02.72.92.9
Food consumed during 24 hour testing period4.55.57.1-2.3-2.6-2.4-2.50.0-2.4-2.7-2.6
Times rat made contact with spout0.91.01.41.21.01.10.90.01.11.11.0
Mean time between licks in bursts1.01.34.0-0.3-1.7-0.7-2.00.0-0.6-1.0-1.4
Mean num. licks in bursts4.45.37.0-2.2-2.6-2.3-2.60.0-2.3-2.5-2.6
Std. dev. time between licks in bursts0.10.10.40.7-0.20.4-0.50.00.50.1-0.1
Water consumed over 24 hours0.30.30.60.40.70.50.80.00.50.50.7
Indifference point 0 sec3.45.67.5-2.2-2.7-2.4-2.70.0-2.3-2.5-2.7
Indifference point AUC0.30.30.80.90.50.70.30.00.80.50.5
Indifference point function ln k2.43.44.5-2.1-1.9-2.1-1.70.0-2.1-2.1-2.0
Indifference point function log k2.43.44.5-2.1-1.9-2.1-1.70.0-2.1-2.1-2.0
Delay discounting total patch changes 0 sec2.64.25.7-1.9-2.3-2.0-2.40.0-2.0-2.2-2.4
Delay discounting total patch changes 12 sec0.20.20.5-0.0-0.6-0.2-0.70.0-0.1-0.6-0.6
Delay discounting total patch changes 18 sec1.11.42.5-0.9-1.5-1.1-1.60.0-1.1-1.2-1.5
Delay discounting total patch changes 24 sec0.10.20.6-0.1-0.6-0.2-0.80.0-0.1-0.3-0.5
Delay discounting total patch changes 6 sec0.60.91.7-0.8-0.9-0.9-0.90.0-0.8-1.3-1.1
Delay discounting time to switch 0 sec2.43.75.91.52.31.82.40.01.72.22.2
Delay discounting water rate 0 sec2.94.56.1-1.9-2.4-2.1-2.50.0-2.1-2.4-2.4
Delay discounting water rate 12 sec2.63.95.1-1.9-2.3-2.0-2.20.0-2.0-2.1-2.2
Delay discounting water rate 18 sec0.91.22.2-0.8-1.4-1.0-1.50.0-0.9-1.2-1.2
Delay discounting water rate 24 sec2.23.05.0-1.8-1.8-1.8-1.60.0-1.8-2.2-1.9
Delay discounting water rate 6 sec1.62.43.1-1.5-1.8-1.6-1.70.0-1.6-1.7-1.6
Locomotor activity0.60.92.0-0.8-0.9-1.0-0.90.0-0.9-1.4-1.2
Locomotor testing distance1.22.03.0-1.1-1.6-1.3-1.70.0-1.2-1.7-1.7
Locomotor testing rearing0.00.10.20.3-0.30.1-0.40.00.1-0.3-0.3
Light reinforcement 12.34.26.01.82.52.02.40.01.92.42.3
Light reinforcement 20.00.10.2-0.10.40.10.40.00.00.30.3
Reaction time number correct0.70.92.0-1.1-0.8-1.1-0.60.0-1.1-1.4-0.9
Reaction time mean minus median0.20.30.6-0.4-0.7-0.5-0.80.0-0.4-0.6-0.7
Reaction time mean minus median AUC1.01.31.8-1.1-1.3-1.1-1.30.0-1.1-1.3-1.3
Reaction time num false alarms2.63.64.71.92.22.02.10.01.92.02.1
Reaction time num false alarms AUC1.21.72.31.21.51.31.50.01.31.41.4
Reaction time trials correct on left0.70.92.0-1.1-0.8-1.1-0.60.0-1.1-1.4-0.9
Reaction time trials on left0.70.92.0-1.1-0.8-1.1-0.60.0-1.1-1.4-0.9
Reaction time mean1.21.62.21.31.41.31.30.01.31.51.4
Reaction time mean AUC1.31.72.51.21.51.31.40.01.31.61.4
Median of all reaction times1.72.33.31.41.71.51.70.01.51.81.7
Reaction time omissions0.50.70.90.81.00.90.90.00.91.00.9
Reaction time false alarm rate2.13.04.21.81.91.81.80.01.82.01.9
Reaction time premature initiation rate0.10.10.60.4-0.40.2-0.70.00.30.1-0.2
Reaction time premature initiations0.40.51.3-0.4-1.0-0.5-1.10.0-0.5-0.8-0.8
Std. dev. reaction times0.20.20.60.80.40.60.10.00.70.40.4
Reaction time trials completed0.70.92.0-1.1-0.8-1.1-0.60.0-1.1-1.4-0.9
Reaction time trials AUC0.50.71.7-0.9-0.7-0.9-0.50.0-1.0-1.3-0.8
Social response proportion0.60.71.01.00.70.90.60.01.00.90.9
Social responses1.11.42.11.51.01.40.80.01.41.51.2
Social time1.51.93.11.11.61.21.70.01.21.81.7
Conditioned locomotion0.00.00.0-0.2-0.0-0.20.10.0-0.20.0-0.0
Cocaine response after cond. corrected2.83.14.51.81.91.91.80.01.82.11.9
Cocaine response after cond. not corrected0.70.81.40.80.90.90.90.00.91.21.0
Cocaine response before conditioning2.93.54.4-2.0-2.0-2.0-1.80.0-2.0-2.1-2.1
Saline control response0.91.22.4-0.7-1.4-0.9-1.50.0-0.9-1.1-1.3
Condit. Reinf. active minus inactive responses3.84.78.4-1.5-2.7-1.9-2.90.0-1.8-2.4-2.6
Condit. Reinf. active-inactive response ratio1.31.32.1-0.9-1.4-1.1-1.50.0-1.1-1.2-1.3
Condit. Reinf. active responses4.25.811.2-1.6-3.1-2.1-3.30.0-1.9-2.7-2.9
Condit. Reinf. inactive responses1.92.45.0-0.9-2.0-1.2-2.20.0-1.1-1.8-1.9
Condit. Reinf. lever presses12.016.626.2-3.3-4.9-3.8-5.10.0-3.7-4.5-4.7
Condit. Reinf. lever reinforcers received5.37.513.5-1.9-3.4-2.4-3.70.0-2.2-3.1-3.2
Pavlov. Cond. lever latency13.218.127.13.65.14.15.20.03.94.84.9
Pavlov. Cond. magazine entry latency4.45.06.7-2.1-2.6-2.3-2.60.0-2.2-2.4-2.5
Pavlov. Cond. change in total contacts11.315.822.4-3.5-4.7-3.9-4.70.0-3.7-4.5-4.6
Pavlov. Cond. index score11.014.321.1-3.3-4.5-3.7-4.60.0-3.5-4.2-4.4
Pavlov. Cond. latency score10.112.718.5-3.1-4.2-3.5-4.30.0-3.3-4.0-4.1
Pavlov. Cond. lever contacts13.819.228.6-3.7-5.2-4.2-5.30.0-4.0-4.9-5.1
Pavlov. Cond. magazine entry number7.59.212.22.83.53.03.50.03.03.43.5
Pavlov. Cond. intertrial magazine entries0.50.61.21.10.61.00.40.01.01.00.7
Pavlov. Cond. lever-magazine prob. diff.9.912.819.3-3.1-4.3-3.4-4.40.0-3.3-3.9-4.2
Pavlov. Cond. response bias14.720.329.7-3.9-5.4-4.4-5.40.0-4.2-5.0-5.2
Conditioned reinforcement - actives3.93.85.1-2.0-2.1-2.1-2.00.0-2.1-2.1-2.3
Conditioned reinforcement - inactives0.30.31.00.50.40.50.40.00.51.00.5
Conditioned locomotion4.35.16.5-2.4-2.4-2.4-2.20.0-2.4-2.5-2.5
Intermittent access intake day 1-15 change0.80.81.9-0.7-0.9-0.8-0.90.0-0.8-1.4-1.0
Intermittent access intake escalation1.01.02.5-0.8-1.0-1.0-1.00.0-0.9-1.6-1.1
Intermittent access intake escalation 20.10.10.60.2-0.10.0-0.20.00.1-0.8-0.2
Intermitt. access day 1 inactive lever presses0.50.61.10.80.70.80.60.00.81.00.9
Intermitt. access day 15 inactive lever presses0.30.30.6-0.8-0.6-0.7-0.50.0-0.7-0.3-0.6
Intermitt. access escalation Index0.40.30.8-0.4-0.6-0.5-0.50.0-0.5-0.9-0.7
Intermittent access day 1 total infusions1.01.12.0-1.1-1.4-1.1-1.40.0-1.1-0.6-1.2
Intermittent access day 15 total infusions2.02.23.1-1.4-1.7-1.5-1.70.0-1.5-1.6-1.7
Intermittent access terminal intake (last 3 days)1.41.52.1-1.1-1.5-1.2-1.50.0-1.2-1.3-1.5
Intermittent access total infusions1.01.11.9-1.0-1.4-1.1-1.40.0-1.0-0.8-1.2
Intermittent access day 1 locomotion0.30.30.6-0.7-0.6-0.6-0.50.0-0.6-0.3-0.6
Intermittent access day 15 total locomotion1.81.92.8-1.4-1.5-1.4-1.40.0-1.4-1.7-1.6
Intermittent access total locomotion0.80.91.2-1.0-1.1-1.0-1.10.0-1.0-0.7-1.1
Intermittent access standard deviation0.00.00.00.20.00.1-0.10.00.1-0.00.0
Cocaine induced anxiety1.92.13.31.31.81.41.80.01.41.61.6
Post-drug Anxiety1.31.51.81.31.31.31.30.01.31.31.3
Baseline Anxiety0.60.71.5-0.5-1.1-0.7-1.20.0-0.6-0.9-0.9
Lifetime Intake1.41.52.6-1.2-1.6-1.3-1.60.0-1.2-0.9-1.4
Incentive Sensitization - Responses1.01.01.9-0.6-1.2-0.9-1.30.0-0.8-1.4-1.3
Incentive Sensitization - Breakpoint1.11.12.1-0.7-1.2-0.9-1.30.0-0.9-1.5-1.3
Progressive ratio test 1 active lever presses0.10.10.40.10.10.20.10.00.10.60.3
Progressive ratio test 1 breakpoint0.10.10.40.20.20.30.20.00.30.60.3
Progressive ratio test 1 inactive lever presses0.30.30.6-0.6-0.8-0.5-0.80.0-0.50.4-0.5
Progressive ratio test 2 active lever presses0.40.50.9-0.5-0.8-0.6-0.90.0-0.6-0.7-0.9
Progressive ratio test 2 breakpoint0.40.50.9-0.5-0.8-0.6-0.90.0-0.6-0.7-0.9
Progressive ratio test 2 inactive lever presses1.21.31.8-1.3-1.3-1.3-1.30.0-1.3-0.7-1.4
Total sessions with >9 infusions3.53.85.6-2.0-2.4-2.0-2.30.0-2.0-1.7-2.1
Short access day 1 total inactive lever presses0.10.10.4-0.1-0.1-0.0-0.10.0-0.00.60.2
Short access day 10 total inactive lever presses0.00.00.10.10.30.10.30.00.1-0.20.2
Short access day 1 total infusions2.02.13.7-1.3-1.9-1.4-1.90.0-1.4-1.3-1.7
Short access day 10 total infusions0.70.81.7-0.7-1.2-0.8-1.30.0-0.8-0.6-1.1
Short access total infusions0.80.91.9-0.9-1.3-0.9-1.40.0-0.9-0.4-1.0
Short access day 1 locomotion3.23.44.2-2.1-2.1-2.0-1.90.0-2.0-1.7-2.0
Short access day 10 total locomotion0.10.20.6-0.1-0.3-0.2-0.40.0-0.2-0.8-0.6
Short access total locomotion0.20.20.3-0.4-0.5-0.4-0.50.0-0.4-0.3-0.6
Compulsive drug intake0.10.10.3-0.5-0.1-0.50.00.0-0.5-0.5-0.4
One hour access (0.3 mA shock)1.72.03.0-1.2-1.7-1.4-1.70.0-1.3-1.6-1.6
One hour access (shock baseline)1.01.22.2-0.8-1.4-1.0-1.50.0-0.9-1.2-1.3
Number of responses in last shaping day0.00.00.10.1-0.20.0-0.30.00.10.0-0.2
Context. condit. distance diff. score3.34.05.0-2.1-2.2-2.1-2.10.0-2.0-2.2-2.2
Locomotion velocity, session 10.10.10.2-0.4-0.0-0.30.10.0-0.4-0.2-0.1
Locomotion distance, session 11.21.62.2-1.4-1.3-1.3-1.20.0-1.3-1.5-1.4
Locomotion velocity, session 20.00.00.1-0.0-0.2-0.1-0.30.0-0.1-0.1-0.2
Locomotion distance, session 20.50.71.1-0.9-0.9-0.9-0.80.0-0.9-1.1-1.0
Locomotion velocity, session 31.21.42.1-1.3-1.2-1.3-1.00.0-1.3-1.4-1.3
Locomotion distance, session 32.32.53.7-1.7-1.6-1.7-1.40.0-1.7-1.9-1.7
Stereotopy head waving bouts, day 30.70.81.31.00.91.00.80.01.01.11.0
Stereotopy head waving duration, day 30.10.10.2-0.5-0.4-0.4-0.30.0-0.4-0.4-0.4
Locomotion velocity, session 70.10.10.10.00.30.10.40.00.10.30.3
Locomotion distance, session 70.20.20.20.50.50.50.50.00.50.50.5
Stereotopy head waving bouts, day 73.13.54.4-1.9-2.0-1.9-1.90.0-1.9-2.1-2.1
Stereotopy head waving duration, day 73.13.85.0-2.0-2.2-2.0-2.10.0-1.9-2.2-2.2
Locomotion velocity, session 80.91.11.4-1.0-1.2-1.1-1.20.0-1.0-1.1-1.1
Locomotion distance, session 82.63.94.9-2.1-2.2-2.0-2.10.0-2.0-2.2-2.2
Degree of sensitization distance2.42.53.61.91.51.81.20.01.81.91.6
Degree of sensitization stereotypy6.67.29.3-2.7-3.0-2.8-2.80.0-2.7-3.0-3.0
Condit. Reinf. active minus inactive responses0.00.00.10.3-0.10.2-0.20.00.20.10.0
Condit. Reinf. active-inactive response ratio0.10.10.30.2-0.40.0-0.50.00.1-0.1-0.2
Condit. Reinf. active responses0.00.10.10.30.20.30.10.00.30.20.2
Condit. Reinf. inactive responses0.00.00.1-0.00.20.00.20.00.00.10.1
Incentive salience index mean0.00.00.10.2-0.20.0-0.30.00.1-0.2-0.1
Condit. Reinf. lever presses0.00.00.1-0.0-0.2-0.1-0.30.0-0.1-0.3-0.2
Time in familiar zone, hab. session 10.10.10.20.40.20.40.10.00.40.40.3
Time in novel zone, hab. session 10.20.20.40.40.60.50.60.00.50.50.6
Total zone transitions, hab. session 10.20.30.6-0.8-0.3-0.6-0.20.0-0.7-0.6-0.5
Total locomotion distance, hab. session 11.72.53.21.81.71.81.40.01.81.61.7
Locomotion velocity, hab. session 11.01.41.81.31.31.31.10.01.41.21.2
Time in familiar zone, hab. session 21.01.01.8-0.8-1.3-0.9-1.40.0-0.8-1.0-1.1
Time in novel zone, hab. session 20.10.10.30.20.50.20.60.00.20.30.4
Total zone transitions, hab. session 22.02.63.4-1.8-1.7-1.7-1.60.0-1.7-1.9-1.8
Total locomotion distance, hab. session 20.40.60.91.00.60.90.40.01.00.90.7
Locomotion velocity, hab. session 20.71.01.51.20.91.20.60.01.21.21.0
Novel to familiar place preference ratio0.10.10.1-0.3-0.3-0.3-0.20.0-0.3-0.3-0.3
Novelty place preference0.10.10.1-0.3-0.3-0.3-0.20.0-0.3-0.3-0.3
Time in novel zone, NPP test0.20.20.3-0.5-0.5-0.5-0.40.0-0.5-0.5-0.5
Total zone transitions, NPP test0.50.71.0-1.0-0.7-0.9-0.70.0-0.9-1.0-0.9
Total locomotion distance, NPP test1.01.52.01.41.21.41.00.01.41.31.3
Locomotion velocity, NPP test1.52.22.71.61.51.61.40.01.61.61.6
Pavlov. Cond. lever latency0.91.11.70.81.21.01.30.00.91.21.2
Pavlov. Cond. magazine entry latency1.92.54.2-1.3-2.0-1.5-2.00.0-1.4-1.7-1.8
Pavlov. Cond. change in total contacts1.01.11.9-0.8-1.3-0.9-1.40.0-0.9-1.1-1.2
Pavlov. Cond. index score1.82.44.0-1.2-1.9-1.4-2.00.0-1.3-1.7-1.8
Pavlov. Cond. latency score1.92.43.9-1.2-1.9-1.4-2.00.0-1.4-1.7-1.8
Pavlov. Cond. lever contacts0.60.71.4-0.5-1.1-0.7-1.20.0-0.7-0.9-1.0
Pavlov. Cond. magazine entry number2.73.35.21.52.21.72.30.01.72.02.1
Pavlov. Cond. intertrial magazine entries0.60.71.10.61.10.81.10.00.80.91.0
Pavlov. Cond. lever-magazine prob. diff.1.51.93.3-1.1-1.7-1.3-1.80.0-1.2-1.5-1.6
Pavlov. Cond. response bias0.60.81.5-0.6-1.1-0.8-1.20.0-0.7-1.0-1.0
Bone: apparent density0.00.00.1-0.1-0.0-0.20.00.0-0.3-0.3-0.1
Bone surface0.61.01.5-0.7-1.2-1.0-1.20.0-0.9-1.1-1.2
Bone volume0.40.60.9-0.6-1.0-0.8-1.00.0-0.8-1.0-0.9
Bone: connectivity density0.20.30.6-0.6-0.5-0.7-0.40.0-0.7-0.8-0.6
Bone: cortical apparent density2.73.54.12.02.02.01.90.02.02.02.0
Bone: cortical area0.10.10.30.1-0.5-0.2-0.50.0-0.1-0.3-0.4
Bone: cortical porosity1.71.82.5-1.6-1.4-1.5-1.20.0-1.5-1.4-1.5
Bone: cortical porosity1.51.62.2-1.5-1.3-1.4-1.10.0-1.4-1.3-1.3
Bone: cortical thickness0.10.10.20.30.40.30.40.00.30.20.3
Bone: cortical thickness0.30.30.5-0.5-0.6-0.6-0.50.0-0.6-0.7-0.6
Bone: cortical tissue density2.63.34.01.92.01.91.90.01.92.02.0
Bone: elastic displacement0.91.12.20.61.40.91.50.00.81.11.2
Bone: elastic work0.60.71.70.41.20.61.30.00.50.91.0
Bone: endosteal estimation0.20.41.40.0-1.0-0.3-1.20.0-0.3-0.5-0.8
Bone: endosteal perimeter0.40.92.2-0.3-1.3-0.7-1.50.0-0.6-0.9-1.1
Bone: final force0.00.00.00.20.10.20.10.00.20.20.2
Bone: final moment0.00.00.00.0-0.10.0-0.10.00.0-0.0-0.0
Bone: marrow area0.10.31.00.2-0.8-0.2-1.00.0-0.1-0.3-0.6
Bone: maximum diameter0.61.22.5-0.6-1.4-0.9-1.60.0-0.8-1.1-1.3
Bone: maximum force0.00.00.0-0.0-0.2-0.1-0.20.0-0.0-0.1-0.1
Bone: maximum moment0.00.10.2-0.2-0.4-0.2-0.40.0-0.2-0.3-0.3
Bone: minimum diameter0.20.41.21.10.20.8-0.10.00.90.60.4
Bone: periosteal estimation0.20.41.30.0-1.0-0.4-1.10.0-0.3-0.6-0.8
Bone: periosteal perimeter0.40.61.5-0.3-1.1-0.6-1.20.0-0.5-0.8-1.0
Bone: post-yield work0.10.20.3-0.4-0.5-0.4-0.50.0-0.4-0.5-0.5
Bone: stiffness0.50.71.11.00.81.00.70.01.00.90.9
Bone: tissue strength0.30.30.7-0.9-0.3-0.7-0.10.0-0.8-0.6-0.4
Bone: trabecular number0.20.30.80.30.80.30.90.00.30.40.6
Bone: trabecular spacing0.81.11.5-1.1-1.2-1.0-1.20.0-1.0-1.1-1.2
Bone: trabecular thickness0.30.40.60.80.70.60.60.00.60.70.7
Bone: trabecular tissue density2.94.05.52.32.02.21.80.02.32.22.1
Breakpoint value in progressive ratio session0.00.00.1-0.30.2-0.10.30.0-0.20.10.1
Distance traveled before self-admin1.41.52.41.21.51.31.50.01.31.01.3
Distance traveled after self-admin0.10.10.4-0.6-0.1-0.40.10.0-0.5-0.3-0.1
Delta time in closed arm before/after self-admin4.54.46.02.42.12.31.80.02.42.42.2
Delta time in open arm before/after self-admin3.23.14.6-1.6-2.1-1.7-2.20.0-1.7-1.8-2.0
Diff in mean of infusions in LGA sessions3.53.95.11.82.22.02.20.02.02.32.3
Extinction: sum of active levers before priming0.10.10.40.20.30.30.30.00.30.60.4
Active lever presses in extinction session 65.04.86.8-2.6-2.1-2.4-1.90.0-2.4-2.6-2.4
Delta distance traveled before/after self-admin2.32.53.4-1.8-1.8-1.7-1.70.0-1.7-1.4-1.6
Delta ambulatory time before/after self-admin2.83.03.9-2.0-2.0-1.9-1.80.0-2.0-1.6-1.7
Time in closed arm before self-admin4.95.67.7-2.7-2.4-2.6-2.10.0-2.6-2.8-2.5
Time in closed arm after self-admin0.10.10.4-0.10.50.10.60.00.10.20.4
Time in open arm before self-admin5.76.18.42.52.92.62.80.02.52.52.7
Time in open arm after self-admin0.20.20.50.70.20.50.00.00.60.30.2
Sum of active levers in priming session hrs 5-60.00.00.1-0.10.3-0.00.40.0-0.1-0.20.1
Time to tail flick, vehicle, before self-admin0.00.00.0-0.20.0-0.10.10.0-0.1-0.1-0.0
Time to tail flick, vehicle, after self-admin3.43.75.1-2.1-2.3-2.0-2.20.0-2.0-1.7-2.0
Time to tail flick, test, before self-admin0.00.00.10.0-0.3-0.1-0.40.0-0.00.0-0.2
Time to tail flick, test, after self-admin0.10.10.30.60.00.5-0.10.00.50.40.2
Delta time to tail flick, vehicle, before/after SA2.22.13.3-1.6-1.8-1.5-1.80.0-1.5-1.0-1.5
Delta time to tail flick, test, before/after SA0.30.30.40.60.60.60.50.00.60.60.7
Ambulatory time before self-admin1.11.11.80.91.41.11.30.01.00.91.2
Ambulatory time after self-admin0.50.61.4-1.2-0.6-1.0-0.30.0-1.0-0.7-0.6
Total heroin consumption0.50.60.9-0.9-0.8-0.9-0.70.0-0.9-0.9-0.9
Area under the delay curve0.20.20.40.50.60.40.60.00.50.20.3
Delay disc. indifference point, 0s delay0.40.40.6-0.4-0.7-0.6-0.80.0-0.5-0.8-0.8
Delay disc. indifference point, 16s delay0.00.00.2-0.00.30.10.40.00.0-0.10.1
Delay disc. indifference point, 2s delay0.00.00.10.1-0.2-0.0-0.30.00.0-0.3-0.3
Delay disc. indifference point, 24s delay0.80.81.80.71.20.81.30.00.80.60.9
Delay disc. indifference point, 4s delay0.00.00.10.3-0.10.2-0.30.00.2-0.2-0.2
Delay disc. indifference point, 8s delay0.00.00.00.10.10.00.00.00.00.0-0.1
Delay discount exponential model param0.20.20.4-0.5-0.7-0.5-0.70.0-0.5-0.2-0.4
Delay discount hyperbolic model param0.20.20.3-0.5-0.5-0.4-0.50.0-0.5-0.2-0.3
Fecal boli incidents, locomotor time 11.61.72.1-1.4-1.4-1.4-1.30.0-1.4-1.5-1.4
Change in fecal boli incidents, locomotor task1.21.11.61.11.11.11.10.01.11.21.3
Time >=10cm from walls, locomotor time 12.52.63.2-1.7-1.7-1.7-1.60.0-1.7-1.8-1.8
Bouts of movement, locomotor time 10.30.30.6-0.6-0.5-0.6-0.40.0-0.6-0.7-0.6
Total resting periods, locomotor time 10.40.40.8-0.9-0.6-0.8-0.40.0-0.8-0.8-0.7
Rest time, locomotor task time 10.10.10.3-0.5-0.4-0.4-0.20.0-0.5-0.1-0.3
Distance moved, locomotor task time 10.20.30.70.80.40.60.20.00.70.30.4
Vertical activity count, locomotor time 10.00.00.10.3-0.10.2-0.30.00.20.2-0.1
Time >=10cm from walls, locomotor time 21.11.21.9-1.0-1.4-1.0-1.40.0-1.0-1.0-1.2
Bouts of movement, locomotor time 20.10.10.30.60.30.50.10.00.5-0.00.2
Total resting periods, locomotor time 20.30.30.60.80.60.70.40.00.70.40.5
Rest time, locomotor task time 22.32.64.61.31.81.51.90.01.42.21.9
Distance moved, locomotor task time 21.92.23.5-1.0-1.8-1.3-1.90.0-1.2-1.8-1.7
Vertical activity count, locomotor time 20.30.31.0-0.2-0.8-0.4-1.00.0-0.3-0.5-0.7
Weight adjusted by age0.00.00.10.4-0.10.2-0.30.00.20.0-0.1
Seeking ratio, delayed vs. immediate footshock0.40.51.30.20.80.50.90.00.41.10.9
Locomotion in novel chamber1.51.84.1-1.5-1.1-1.4-1.00.0-1.4-2.0-1.4
Locomotion in novel chamber post-restriction3.13.74.5-2.1-2.1-2.0-1.90.0-2.0-2.1-2.1
Progressive ratio0.10.20.4-0.6-0.3-0.5-0.20.0-0.5-0.5-0.4
Food seeking constrained by brief footshock0.10.10.40.2-0.5-0.1-0.60.0-0.1-0.5-0.5
Seeking ratio, punishment vs. effort0.10.10.50.7-0.10.3-0.40.00.40.10.0
Run reversals in cocaine runway, females3.43.35.22.31.62.11.20.02.22.31.9
Run reversals in cocaine runway, males0.00.00.1-0.00.10.00.20.00.00.40.1
Latency to leave start box in cocaine runway3.94.36.22.22.12.22.00.02.12.52.3
Latency to leave start box in cocaine runway, F4.14.56.52.42.12.31.90.02.32.52.3
Latency to leave start box in cocaine runway, M0.00.00.1-0.00.30.10.40.00.10.20.3
Cd content in liver1.11.21.51.21.21.21.10.01.21.21.2
Co content in liver0.40.51.2-0.3-1.0-0.5-1.10.0-0.4-0.6-0.8
Cu content in liver0.10.10.30.2-0.4-0.0-0.60.00.0-0.2-0.3
Fe content in liver0.10.10.10.30.30.30.20.00.30.30.3
K content in liver0.50.50.70.80.70.80.60.00.80.80.7
Mg content in liver0.00.10.1-0.1-0.3-0.2-0.30.0-0.2-0.2-0.3
Mn content in liver0.30.30.80.10.80.30.90.00.20.60.7
Na content in liver0.30.40.6-0.6-0.7-0.7-0.80.0-0.6-0.5-0.7
Rb content in liver0.40.60.8-0.6-0.9-0.7-0.90.0-0.6-0.9-0.9
Se content in liver2.22.74.11.42.01.52.00.01.51.91.9
Sr content in liver0.20.20.3-0.5-0.4-0.5-0.30.0-0.5-0.4-0.4
Zn content in liver3.74.16.0-1.7-2.4-2.0-2.50.0-1.9-2.2-2.4