Hub : Genes

Mief1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017553 0.06 0.03 7.5e-05 0.03 0.01 0.02 0.03 2.5e-04 7.6e-03 2.8e-03 7.6e-04
2 BLA gene expression ENSRNOG00000017553 0.45 0.12 0.0e+00 0.32 0.25 0.29 0.29 2.2e-17 1.1e-13 1.0e-15 4.9e-16
3 Brain gene expression ENSRNOG00000017553 0.08 0.04 5.7e-07 0.07 0.07 0.06 0.04 6.2e-07 1.6e-07 3.8e-06 7.2e-05
4 IL gene expression ENSRNOG00000017553 0.42 0.14 2.2e-06 0.18 0.09 0.12 0.16 4.3e-05 4.2e-03 9.4e-04 9.7e-05
5 LHb gene expression ENSRNOG00000017553 0.52 0.13 2.9e-08 0.25 0.2 0.22 0.12 1.5e-06 1.4e-05 6.3e-06 9.4e-04
6 Liver alternative TSS ENSRNOT00000092429 0.05 0.03 1.5e-05 0.03 0.04 0.04 0.03 6.9e-04 1.6e-05 1.5e-05 4.3e-04
7 Liver alternative TSS ENSRNOT00000092569 0.05 0.03 1.7e-05 0.03 0.04 0.04 0.03 5.9e-04 1.7e-05 1.8e-05 3.3e-04
8 Liver gene expression ENSRNOG00000017553 0.15 0.07 1.7e-16 0.08 0.14 0.15 0.07 2.9e-09 1.5e-15 4.0e-16 2.4e-08
9 Liver isoform ratio ENSRNOT00000092569 0.06 0.04 1.2e-06 0.04 0.05 0.06 0.04 8.6e-06 7.1e-06 1.1e-07 1.8e-05
10 Liver intron excision ratio chr7:111786808:111788331 0.03 0.03 5.1e-03 0.02 0.01 0.02 0.01 5.2e-03 4.2e-02 3.1e-03 6.9e-03
11 NAcc gene expression ENSRNOG00000017553 0.2 0.09 5.3e-09 0.08 0.1 0.1 0.04 1.2e-06 8.0e-08 5.8e-08 1.1e-03
12 OFC gene expression ENSRNOG00000017553 0.4 0.15 6.7e-05 0.19 0.12 0.2 0.03 3.0e-05 8.6e-04 1.6e-05 7.9e-02
13 PL gene expression ENSRNOG00000017553 0.37 0.1 0.0e+00 0.33 0.33 0.35 0.36 1.7e-25 4.4e-26 3.3e-27 3.1e-28

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.10.41.4-0.30.80.81.21.10.5-0.1-0.0-0.5-0.2-0.10.70.8
BMI without tail0.20.31.81.4-0.5-0.2-0.0-0.20.00.20.3-1.10.7-0.4-0.2-0.3
Body weight0.93.98.3-2.82.11.92.22.20.9-0.6-2.8-0.0-2.91.61.61.7
Epididymis fat weight3.27.412.0-3.23.33.23.23.52.3-2.1-1.8-0.2-1.92.62.93.2
Glucose0.30.42.5-0.2-0.3-0.60.2-0.3-0.90.5-1.6-0.2-0.80.0-0.6-0.2
Heart weight0.71.04.1-2.00.20.50.70.10.30.2-1.80.1-2.01.1-0.4-0.1
Left kidney weight5.716.335.5-6.05.24.14.45.12.2-1.6-3.51.4-5.22.83.84.1
Right kidney weight5.214.940.2-6.34.53.53.84.31.3-0.7-4.12.3-6.32.42.83.2
Tail length0.10.41.9-0.5-0.10.30.0-0.00.3-0.4-1.4-0.6-1.11.1-0.00.1
Length with tail1.14.010.2-3.11.91.81.61.70.8-1.0-3.10.3-3.22.31.41.5
Length without tail1.94.111.9-3.52.21.81.82.00.8-0.8-2.41.1-3.01.91.61.7
Liver weight, left1.42.33.5-1.81.91.81.71.81.5-1.5-0.1-0.6-0.51.71.61.8
Liver weight, right5.38.812.7-2.63.53.43.63.43.1-3.1-1.0-1.9-0.83.53.13.6
Parametrial fat weight0.20.41.2-1.00.30.80.10.51.0-0.60.3-0.6-0.31.10.60.4
Retroperitoneal fat weight3.812.419.9-4.54.33.84.24.42.7-2.2-3.7-0.4-3.03.23.53.8
Intraocular pressure0.71.02.1-1.31.30.91.11.50.5-0.5-1.00.5-1.10.61.21.2
Extensor digitorum longus weight0.41.76.22.5-1.5-0.9-1.2-1.1-0.40.41.4-0.92.0-1.0-0.9-1.0
Soleus weight0.51.33.5-0.1-1.3-1.0-1.9-1.1-1.11.0-0.81.8-0.7-1.0-1.1-1.2
Tibialis anterior weight1.34.69.43.1-2.5-2.2-2.5-2.2-1.51.61.70.42.3-2.5-2.0-2.2
Tibia length0.30.83.1-1.41.10.50.31.0-0.20.3-0.31.1-1.7-0.20.80.5
Number of licking bursts0.50.61.50.7-0.9-0.5-1.2-0.90.10.11.10.31.1-0.5-0.5-0.8
Food consumed during 24 hour testing period0.40.52.2-1.20.2-0.00.30.3-0.20.80.41.1-1.5-0.5-0.3-0.2
Times rat made contact with spout0.40.54.2-0.0-0.40.1-0.9-0.40.40.22.10.30.2-0.4-0.3-0.7
Mean time between licks in bursts0.70.92.71.6-0.9-0.8-0.7-0.9-0.30.21.5-0.61.3-0.7-0.8-0.7
Mean num. licks in bursts0.50.61.2-0.91.11.00.91.10.6-0.40.4-0.3-0.90.60.80.8
Std. dev. time between licks in bursts1.21.42.20.9-1.4-1.5-1.2-1.4-1.51.2-0.80.80.1-1.0-1.3-1.5
Water consumed over 24 hours0.40.54.0-0.2-0.40.1-0.9-0.40.10.32.00.7-0.1-0.4-0.4-0.7
Indifference point 0 sec0.50.81.30.7-1.1-1.1-0.5-1.1-1.10.9-0.90.1-0.5-0.4-1.1-1.1
Indifference point AUC1.21.53.70.7-1.0-1.0-1.9-1.0-0.90.91.91.50.6-1.4-0.7-1.2
Indifference point function ln k2.43.56.6-1.62.11.92.62.21.5-1.5-1.8-1.3-1.32.11.82.2
Indifference point function log k2.43.56.6-1.62.11.92.62.21.5-1.5-1.8-1.3-1.32.11.82.2
Delay discounting total patch changes 0 sec0.61.01.91.1-1.4-1.3-0.8-1.3-1.21.0-0.4-0.10.0-0.7-1.2-1.3
Delay discounting total patch changes 12 sec0.50.71.70.4-0.6-1.0-0.6-0.6-1.31.1-0.01.3-0.3-1.1-0.8-0.8
Delay discounting total patch changes 18 sec2.43.15.00.3-1.9-2.0-1.8-1.8-2.12.2-0.51.9-0.8-2.0-2.0-2.2
Delay discounting total patch changes 24 sec0.70.81.30.7-1.1-1.2-1.2-1.0-0.91.0-0.20.80.5-1.0-0.9-1.1
Delay discounting total patch changes 6 sec2.23.45.90.9-2.2-2.1-2.1-2.2-2.02.10.41.6-0.0-1.9-2.1-2.4
Delay discounting time to switch 0 sec0.20.32.1-0.20.1-0.50.80.3-0.60.7-1.40.3-0.1-0.6-0.10.2
Delay discounting water rate 0 sec0.30.41.10.1-0.9-0.3-1.0-1.0-0.30.3-0.20.5-0.70.3-0.7-0.9
Delay discounting water rate 12 sec0.20.31.30.5-0.10.10.1-0.40.4-0.5-0.4-1.20.40.9-0.1-0.0
Delay discounting water rate 18 sec0.60.71.70.3-1.3-0.7-1.3-1.3-0.60.4-1.00.1-0.60.3-1.0-1.1
Delay discounting water rate 24 sec0.71.04.0-1.20.50.70.80.50.4-0.5-2.0-0.6-1.41.60.40.5
Delay discounting water rate 6 sec0.50.82.91.0-0.10.5-0.3-0.00.7-1.2-1.7-1.00.41.40.60.4
Locomotor activity0.81.23.1-1.61.21.11.21.10.5-0.4-1.80.3-1.51.10.70.8
Locomotor testing distance0.10.20.4-0.20.30.50.10.30.6-0.6-0.2-0.40.60.70.40.2
Locomotor testing rearing0.50.91.6-1.21.31.01.31.20.6-0.5-0.70.2-0.50.80.91.0
Light reinforcement 10.10.10.60.2-0.1-0.5-0.2-0.3-0.40.4-0.8-0.10.3-0.3-0.2-0.4
Light reinforcement 21.62.14.1-0.11.91.42.01.71.4-1.3-1.0-1.50.31.21.61.8
Reaction time number correct0.81.22.80.60.81.00.40.61.4-1.71.0-1.21.41.21.31.1
Reaction time mean minus median0.00.10.50.1-0.1-0.10.1-0.1-0.00.1-0.70.0-0.3-0.0-0.4-0.1
Reaction time mean minus median AUC0.30.40.9-0.70.70.70.90.70.5-0.5-0.6-0.2-0.60.60.30.7
Reaction time num false alarms0.10.10.20.2-0.20.10.2-0.00.2-0.2-0.4-0.4-0.30.5-0.10.1
Reaction time num false alarms AUC0.10.10.30.4-0.20.20.1-0.00.3-0.4-0.5-0.3-0.10.5-0.00.1
Reaction time trials correct on left0.81.22.80.60.81.00.40.61.4-1.71.0-1.21.41.21.31.1
Reaction time trials on left0.81.22.80.60.70.90.30.61.4-1.71.0-1.11.41.21.31.1
Reaction time mean0.10.10.40.1-0.2-0.20.2-0.2-0.30.1-0.7-0.2-0.40.1-0.5-0.1
Reaction time mean AUC0.00.00.30.1-0.1-0.00.2-0.1-0.1-0.0-0.5-0.1-0.30.1-0.30.0
Median of all reaction times0.10.10.30.5-0.4-0.40.0-0.4-0.50.2-0.3-0.1-0.3-0.2-0.6-0.2
Reaction time omissions0.20.31.91.4-0.5-0.4-0.5-0.5-0.20.0-0.20.50.5-0.7-0.5-0.3
Reaction time false alarm rate0.10.10.50.2-0.4-0.20.1-0.2-0.20.3-0.7-0.1-0.5-0.0-0.5-0.3
Reaction time premature initiation rate1.52.07.8-0.3-0.8-1.3-0.3-0.8-1.81.7-2.81.9-1.4-0.7-1.2-1.1
Reaction time premature initiations0.50.74.7-0.2-0.3-0.6-0.0-0.2-0.90.7-2.21.4-0.9-0.0-0.4-0.4
Std. dev. reaction times0.20.31.6-0.80.30.30.50.30.2-0.1-1.30.2-1.10.5-0.10.2
Reaction time trials completed0.81.22.80.60.70.90.30.61.4-1.71.0-1.11.41.21.31.1
Reaction time trials AUC0.71.12.50.30.81.00.50.71.4-1.60.6-1.01.11.21.31.1
Social response proportion0.50.61.31.0-0.7-0.80.2-0.7-0.91.00.4-0.1-0.3-0.9-1.1-0.7
Social responses0.60.81.31.1-0.9-0.9-1.0-0.9-1.00.90.60.60.4-1.1-1.0-1.0
Social time2.73.65.22.2-2.2-2.3-2.0-2.1-2.11.70.60.71.1-2.2-2.1-2.0
Conditioned locomotion0.30.30.5-0.70.60.70.60.70.5-0.50.3-0.1-0.50.70.50.7
Cocaine response after cond. corrected0.30.31.6-0.2-0.2-0.3-0.3-0.0-0.70.6-0.91.3-0.7-0.5-0.4-0.2
Cocaine response after cond. not corrected0.20.20.90.1-0.1-0.3-0.0-0.0-0.60.4-1.00.8-0.4-0.3-0.3-0.1
Cocaine response before conditioning0.30.31.20.50.20.10.6-0.00.5-0.50.2-1.11.10.40.40.3
Saline control response0.60.82.6-0.10.60.90.90.60.8-1.3-0.7-0.90.41.60.71.0
Condit. Reinf. active minus inactive responses0.91.13.8-0.1-0.6-1.0-1.2-0.6-1.31.2-0.41.9-0.8-1.4-0.8-1.0
Condit. Reinf. active-inactive response ratio0.90.92.9-0.4-0.4-0.9-0.7-0.3-1.31.3-0.91.7-1.1-1.1-0.7-0.8
Condit. Reinf. active responses0.40.62.8-0.70.2-0.4-0.40.3-0.80.8-0.31.7-1.1-0.9-0.1-0.2
Condit. Reinf. inactive responses0.20.30.7-0.80.80.40.30.80.2-0.10.20.7-0.4-0.20.80.5
Condit. Reinf. lever presses0.40.50.90.9-0.8-0.9-0.9-0.8-0.80.7-0.00.10.3-1.0-0.7-0.8
Condit. Reinf. lever reinforcers received0.40.62.4-0.60.1-0.6-0.40.1-1.10.9-0.71.6-1.2-1.0-0.2-0.3
Pavlov. Cond. lever latency0.60.81.4-0.81.21.20.61.11.1-0.90.40.40.10.51.11.0
Pavlov. Cond. magazine entry latency3.13.65.31.9-2.3-2.3-2.0-2.3-2.11.9-0.20.80.2-2.0-2.2-2.3
Pavlov. Cond. change in total contacts2.53.56.7-0.2-1.6-2.0-1.1-1.5-2.62.4-2.31.6-2.3-1.5-1.9-1.9
Pavlov. Cond. index score1.62.03.31.3-1.8-1.8-1.4-1.7-1.81.5-0.50.4-0.2-1.3-1.7-1.7
Pavlov. Cond. latency score2.02.54.01.4-2.0-2.0-1.6-1.9-1.91.6-0.60.5-0.2-1.5-1.9-1.9
Pavlov. Cond. lever contacts0.40.61.10.9-1.0-1.0-0.4-0.9-1.00.7-0.6-0.60.1-0.4-0.9-0.8
Pavlov. Cond. magazine entry number1.11.32.1-1.11.41.51.21.41.4-1.30.5-0.40.11.11.31.4
Pavlov. Cond. intertrial magazine entries0.50.73.3-1.60.70.50.40.50.20.1-0.81.8-0.9-0.10.20.3
Pavlov. Cond. lever-magazine prob. diff.1.41.83.01.4-1.7-1.7-1.3-1.6-1.71.4-0.70.3-0.2-1.2-1.5-1.6
Pavlov. Cond. response bias1.01.42.51.0-1.4-1.6-0.9-1.3-1.61.4-0.80.2-0.2-1.2-1.4-1.4
Conditioned reinforcement - actives0.70.73.90.3-0.5-0.4-1.1-0.5-0.40.42.01.00.4-1.0-0.3-0.6
Conditioned reinforcement - inactives2.22.44.20.5-1.8-1.7-2.1-1.9-1.51.61.01.00.3-1.7-1.8-2.0
Conditioned locomotion0.81.02.9-0.3-0.5-0.8-0.8-0.5-1.21.40.81.7-0.9-1.5-0.9-1.0
Intermittent access intake day 1-15 change0.30.31.30.8-0.6-0.2-0.8-0.70.0-0.31.2-0.30.50.1-0.3-0.4
Intermittent access intake escalation0.30.31.30.8-0.6-0.3-0.7-0.7-0.1-0.21.1-0.40.5-0.0-0.4-0.4
Intermittent access intake escalation 20.30.30.60.3-0.8-0.4-0.7-0.8-0.20.10.8-0.20.3-0.0-0.6-0.6
Intermitt. access day 1 inactive lever presses1.01.11.9-0.4-0.7-1.0-0.6-0.8-1.31.4-1.11.2-1.4-0.9-1.1-1.0
Intermitt. access day 15 inactive lever presses0.70.82.5-0.5-0.6-0.6-1.1-0.7-0.81.0-0.41.6-1.0-0.8-0.8-0.9
Intermitt. access escalation Index0.30.30.80.7-0.5-0.3-0.6-0.40.10.20.9-0.40.9-0.3-0.3-0.4
Intermittent access day 1 total infusions0.70.82.7-0.6-0.3-0.7-0.4-0.4-1.01.3-0.41.7-0.8-1.4-0.7-0.7
Intermittent access day 15 total infusions1.01.11.70.3-0.9-1.0-1.2-1.1-1.11.10.61.3-0.3-1.3-1.2-1.2
Intermittent access terminal intake (last 3 days)0.50.50.90.1-0.7-0.7-0.9-0.8-0.60.71.00.80.1-0.9-0.8-0.9
Intermittent access total infusions1.11.23.2-0.1-0.7-1.1-0.8-0.9-1.21.50.41.6-0.3-1.8-1.2-1.2
Intermittent access day 1 locomotion0.90.91.8-0.3-0.7-0.9-0.6-0.7-1.11.30.41.3-0.8-1.2-1.1-1.1
Intermittent access day 15 total locomotion0.20.20.8-0.90.0-0.1-0.2-0.2-0.20.50.50.8-0.6-0.4-0.4-0.4
Intermittent access total locomotion0.91.02.4-1.6-0.4-0.6-0.5-0.6-0.91.3-0.11.5-1.5-0.8-1.0-1.0
Intermittent access standard deviation0.70.82.0-0.3-0.3-0.8-0.0-0.5-1.31.1-0.51.4-1.2-1.0-0.9-0.6
Cocaine induced anxiety0.70.82.4-1.61.00.71.41.10.8-0.2-0.4-0.7-0.50.50.60.8
Post-drug Anxiety0.60.72.5-1.60.60.60.90.60.4-0.1-1.3-0.1-1.21.10.30.4
Baseline Anxiety0.40.41.40.5-0.9-0.4-1.2-0.9-0.4-0.00.30.20.30.4-0.6-0.8
Lifetime Intake1.21.43.9-0.5-0.5-1.1-0.6-0.7-1.31.7-0.22.0-0.7-2.0-1.1-1.1
Incentive Sensitization - Responses0.10.10.3-0.50.20.2-0.10.10.3-0.5-0.5-0.00.20.40.30.3
Incentive Sensitization - Breakpoint0.20.20.5-0.70.30.40.00.30.4-0.5-0.60.10.00.40.40.4
Progressive ratio test 1 active lever presses1.21.33.30.0-0.8-1.2-1.2-0.8-1.31.60.51.5-0.1-1.8-1.1-1.3
Progressive ratio test 1 breakpoint0.80.81.8-0.1-0.7-0.8-1.1-0.7-0.91.10.81.10.0-1.3-0.8-1.0
Progressive ratio test 1 inactive lever presses1.61.73.90.6-1.2-1.7-0.9-1.2-1.41.8-0.11.0-0.1-2.0-1.5-1.4
Progressive ratio test 2 active lever presses0.50.51.6-0.5-0.4-0.6-0.9-0.5-0.70.80.01.3-0.1-1.1-0.5-0.7
Progressive ratio test 2 breakpoint0.70.72.4-0.6-0.5-0.8-0.9-0.6-0.91.0-0.11.5-0.3-1.3-0.7-0.8
Progressive ratio test 2 inactive lever presses1.41.63.40.7-1.2-1.5-1.5-1.4-1.31.30.41.20.4-1.8-1.4-1.5
Total sessions with >9 infusions0.70.72.4-1.40.2-0.30.10.2-0.81.1-0.61.6-1.3-1.0-0.3-0.4
Short access day 1 total inactive lever presses3.23.66.5-0.0-1.7-1.9-1.7-1.6-2.32.5-0.82.5-1.3-2.2-2.0-2.2
Short access day 10 total inactive lever presses0.70.83.5-1.60.00.2-0.0-0.2-0.20.1-1.61.0-1.90.8-0.3-0.2
Short access day 1 total infusions0.50.61.4-0.7-0.3-0.6-0.1-0.3-0.71.0-1.01.2-0.9-1.0-0.6-0.6
Short access day 10 total infusions0.91.03.3-0.80.1-0.60.20.0-1.11.5-0.51.8-1.2-1.5-0.7-0.5
Short access total infusions1.21.34.4-1.2-0.1-0.80.1-0.2-1.21.7-1.02.1-1.3-1.6-0.9-0.7
Short access day 1 locomotion0.90.91.90.1-0.9-1.2-0.6-0.9-1.21.3-0.30.9-0.3-1.4-1.2-1.1
Short access day 10 total locomotion1.21.32.50.3-1.4-1.4-0.8-1.4-1.21.40.30.6-0.7-1.1-1.6-1.4
Short access total locomotion1.31.43.0-0.8-0.7-1.1-0.4-0.8-1.41.7-0.11.6-1.5-1.4-1.3-1.1
Compulsive drug intake0.70.72.30.9-0.9-0.4-1.5-1.00.2-0.31.3-0.31.30.1-0.3-0.7
One hour access (0.3 mA shock)1.51.84.91.5-1.0-1.2-1.3-1.2-0.80.92.20.61.6-1.8-1.0-1.2
One hour access (shock baseline)0.20.20.90.4-0.1-0.40.2-0.1-0.40.50.70.30.3-1.0-0.4-0.2
Number of responses in last shaping day3.43.49.41.5-1.7-2.4-1.3-1.6-2.42.40.51.20.5-3.1-1.8-1.8
Context. condit. distance diff. score5.97.210.7-2.73.03.33.13.23.0-2.5-0.5-1.7-1.33.12.83.0
Locomotion velocity, session 10.80.84.0-0.6-0.4-0.5-1.3-0.3-0.90.8-0.42.0-1.1-0.8-0.5-0.8
Locomotion distance, session 12.22.96.92.0-1.7-1.7-2.6-1.7-1.41.11.31.51.4-2.2-1.2-1.7
Locomotion velocity, session 20.10.10.5-0.30.2-0.10.30.3-0.20.3-0.60.7-0.1-0.50.20.1
Locomotion distance, session 24.26.010.32.3-2.6-2.8-3.0-2.5-2.72.50.12.41.0-3.2-2.3-2.7
Locomotion velocity, session 32.93.36.3-0.82.02.21.72.12.0-2.2-0.2-1.40.12.22.52.2
Locomotion distance, session 31.31.43.20.90.41.0-0.30.51.4-1.71.4-1.51.81.01.30.8
Stereotopy head waving bouts, day 30.60.73.5-1.10.2-0.10.30.2-0.60.8-1.91.1-1.5-0.3-0.1-0.2
Stereotopy head waving duration, day 31.31.65.7-2.11.00.61.41.0-0.20.5-2.20.9-2.40.50.50.5
Locomotion velocity, session 71.21.42.7-1.61.41.11.21.51.0-0.9-1.30.1-0.71.01.31.4
Locomotion distance, session 70.40.52.0-0.9-0.1-0.3-0.5-0.0-0.50.6-1.31.4-0.8-0.4-0.2-0.3
Stereotopy head waving bouts, day 73.33.86.0-2.22.12.02.52.21.7-1.5-2.0-1.1-1.02.22.22.1
Stereotopy head waving duration, day 73.54.27.8-1.52.22.12.82.32.2-1.9-0.8-2.20.02.42.32.3
Locomotion velocity, session 81.01.25.0-2.21.00.80.81.10.4-0.0-1.41.1-1.60.70.70.7
Locomotion distance, session 80.60.81.5-0.31.11.11.11.21.0-1.0-0.3-0.5-0.00.91.11.1
Degree of sensitization distance2.02.16.6-1.90.0-0.60.70.0-1.21.5-2.62.0-2.5-0.6-1.0-0.4
Degree of sensitization stereotypy3.23.55.0-1.42.02.12.22.12.1-1.9-0.7-1.6-0.12.22.22.2
Condit. Reinf. active minus inactive responses0.10.10.20.4-0.2-0.3-0.4-0.3-0.30.2-0.10.10.3-0.2-0.1-0.4
Condit. Reinf. active-inactive response ratio0.40.40.8-0.20.80.80.50.70.7-0.80.2-0.60.00.70.90.7
Condit. Reinf. active responses0.50.72.21.5-0.9-0.8-0.7-1.1-0.40.20.0-0.81.3-0.2-0.5-0.8
Condit. Reinf. inactive responses1.11.33.31.8-1.5-1.1-1.0-1.6-0.40.20.3-1.21.8-0.2-1.0-1.1
Incentive salience index mean0.20.30.70.9-0.5-0.5-0.7-0.6-0.50.3-0.3-0.00.6-0.4-0.3-0.6
Condit. Reinf. lever presses0.30.40.91.0-0.7-0.7-0.7-0.7-0.60.4-0.6-0.21.0-0.5-0.4-0.7
Time in familiar zone, hab. session 10.20.20.7-0.1-0.2-0.3-0.7-0.2-0.40.5-0.10.9-0.4-0.7-0.1-0.5
Time in novel zone, hab. session 10.30.31.0-0.60.30.51.00.30.6-0.5-0.1-0.7-0.41.0-0.10.5
Total zone transitions, hab. session 10.91.35.32.3-0.7-0.1-1.5-0.70.4-1.01.2-1.02.30.00.4-0.3
Total locomotion distance, hab. session 10.50.72.11.00.10.5-0.60.10.9-1.40.0-0.91.41.01.00.5
Locomotion velocity, hab. session 10.40.62.71.4-0.30.0-1.0-0.20.3-0.9-0.0-0.61.60.40.60.0
Time in familiar zone, hab. session 21.01.12.20.30.81.10.50.71.3-1.41.2-1.51.11.11.00.9
Time in novel zone, hab. session 21.11.12.4-0.3-0.8-1.0-0.6-0.7-1.31.3-1.11.5-1.1-1.0-1.1-0.9
Total zone transitions, hab. session 21.82.35.01.4-1.7-1.6-2.2-1.6-1.51.4-0.21.50.4-1.8-1.3-1.9
Total locomotion distance, hab. session 21.62.13.21.1-1.6-1.7-1.8-1.6-1.61.4-0.31.50.1-1.6-1.6-1.7
Locomotion velocity, hab. session 22.12.84.51.4-1.9-2.0-2.1-1.9-1.91.6-0.41.50.3-1.8-1.8-2.0
Novel to familiar place preference ratio1.01.12.3-1.01.01.51.00.91.5-1.0-0.1-0.7-0.91.50.80.9
Novelty place preference1.81.93.8-1.21.32.01.31.32.0-1.50.1-1.0-0.91.91.21.3
Time in novel zone, NPP test2.12.24.6-1.31.52.11.41.42.1-1.60.2-1.0-0.92.01.31.4
Total zone transitions, NPP test1.21.85.32.3-1.4-0.9-2.3-1.4-0.4-0.11.40.31.8-0.9-0.5-1.1
Total locomotion distance, NPP test0.60.92.71.2-1.0-0.9-1.6-1.0-0.80.40.41.00.7-0.8-0.6-0.9
Locomotion velocity, NPP test0.71.02.81.6-1.1-1.0-1.7-1.1-0.80.30.50.81.1-0.9-0.6-0.9
Pavlov. Cond. lever latency0.20.20.9-1.00.20.50.10.40.4-0.10.20.4-0.80.30.00.2
Pavlov. Cond. magazine entry latency1.01.32.71.4-1.0-1.3-1.2-1.1-1.21.10.90.50.8-1.6-1.0-1.2
Pavlov. Cond. change in total contacts2.32.54.61.5-1.5-1.9-1.6-1.8-1.81.70.51.00.7-2.1-1.6-1.8
Pavlov. Cond. index score0.40.51.30.6-0.4-0.9-0.6-0.6-1.00.90.00.60.1-1.1-0.6-0.7
Pavlov. Cond. latency score0.20.30.70.6-0.4-0.7-0.4-0.5-0.80.7-0.10.40.2-0.8-0.5-0.6
Pavlov. Cond. lever contacts0.40.51.01.0-0.6-1.0-0.5-0.8-0.80.6-0.10.20.7-0.9-0.7-0.7
Pavlov. Cond. magazine entry number0.50.61.3-0.90.50.70.90.70.7-0.6-1.0-0.4-0.61.10.50.7
Pavlov. Cond. intertrial magazine entries1.11.32.60.8-1.6-1.2-1.6-1.6-1.01.0-0.70.80.2-0.6-1.2-1.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.8-0.4-0.8-0.6-0.6-0.80.70.30.40.5-1.1-0.5-0.6
Pavlov. Cond. response bias0.70.82.01.0-0.6-1.1-0.8-0.8-1.20.90.40.60.5-1.4-0.7-0.9
Bone: apparent density0.20.31.50.6-0.6-0.5-0.3-0.4-0.40.4-1.2-0.10.1-0.3-0.2-0.5
Bone surface0.20.32.20.2-0.2-0.4-0.4-0.1-0.70.5-1.50.5-0.5-0.50.1-0.4
Bone volume0.10.11.40.30.1-0.00.00.2-0.10.1-1.2-0.1-0.0-0.20.5-0.1
Bone: connectivity density0.20.32.6-0.1-0.3-0.3-0.3-0.2-0.40.4-1.60.4-0.5-0.1-0.2-0.4
Bone: cortical apparent density0.70.91.90.40.50.90.00.31.3-1.40.9-1.41.31.01.00.6
Bone: cortical area0.30.51.7-0.80.50.10.60.6-0.30.7-1.31.0-1.2-0.60.30.1
Bone: cortical porosity0.80.83.7-1.30.4-0.11.10.5-0.50.6-1.90.9-1.50.0-0.10.4
Bone: cortical porosity1.41.56.6-1.60.5-0.11.30.7-0.80.9-2.61.5-1.9-0.2-0.10.4
Bone: cortical thickness0.10.21.10.3-0.3-0.4-0.3-0.1-0.30.70.20.80.3-1.0-0.2-0.4
Bone: cortical thickness0.91.03.10.9-0.8-0.9-1.1-0.8-0.71.20.91.20.5-1.8-0.8-1.1
Bone: cortical tissue density0.70.92.00.30.60.90.00.41.3-1.40.9-1.31.21.11.10.7
Bone: elastic displacement0.20.20.5-0.70.30.40.20.50.3-0.3-0.60.1-0.70.60.40.4
Bone: elastic work0.81.04.9-1.10.40.00.80.7-0.70.9-1.71.3-2.2-0.4-0.00.1
Bone: endosteal estimation0.61.35.9-1.70.80.10.90.6-0.60.7-2.21.0-2.40.00.20.3
Bone: endosteal perimeter1.22.510.5-1.91.60.91.81.50.2-0.1-3.20.7-2.30.61.11.2
Bone: final force0.61.13.7-1.00.2-0.30.20.3-0.91.4-1.41.5-1.9-1.2-0.1-0.4
Bone: final moment0.71.24.4-1.00.1-0.40.10.2-1.01.5-1.41.6-2.1-1.3-0.2-0.5
Bone: marrow area0.71.46.2-1.70.80.10.90.6-0.60.7-2.21.1-2.50.00.20.3
Bone: maximum diameter1.22.37.9-2.31.40.71.51.3-0.20.7-2.61.4-2.80.00.70.7
Bone: maximum force0.91.65.4-1.40.1-0.40.10.3-1.11.8-1.32.1-2.3-1.5-0.3-0.6
Bone: maximum moment1.01.76.1-1.50.0-0.40.10.2-1.21.9-1.32.1-2.5-1.5-0.3-0.7
Bone: minimum diameter0.51.04.7-1.20.4-0.10.60.4-0.60.8-2.21.2-1.7-0.50.10.1
Bone: periosteal estimation0.71.35.0-1.60.90.11.00.7-0.60.9-2.21.2-2.2-0.40.30.2
Bone: periosteal perimeter1.72.811.0-2.21.50.91.91.6-0.00.3-3.31.2-2.90.31.01.0
Bone: post-yield work1.52.03.8-0.1-1.2-1.3-1.6-1.2-1.51.90.61.9-0.6-1.9-1.3-1.7
Bone: stiffness0.81.33.9-1.1-0.2-0.60.2-0.1-1.11.7-1.61.5-2.0-1.2-0.5-0.7
Bone: tissue strength0.20.20.8-0.60.40.40.40.50.1-0.2-0.50.1-0.90.40.60.5
Bone: trabecular number0.50.82.7-0.20.80.90.71.00.9-1.0-1.6-0.60.11.01.10.9
Bone: trabecular spacing0.91.24.5-1.3-0.3-0.7-0.6-0.4-1.11.50.52.1-1.4-1.2-0.8-0.8
Bone: trabecular thickness0.60.71.90.60.40.50.90.50.8-0.8-1.3-1.40.90.70.80.6
Bone: trabecular tissue density0.91.22.61.5-1.5-1.1-0.7-1.6-0.70.71.0-1.10.9-0.3-1.2-1.3
Breakpoint value in progressive ratio session0.40.40.60.8-0.7-0.8-0.4-0.7-0.80.7-0.30.10.1-0.7-0.7-0.7
Distance traveled before self-admin1.11.23.21.1-1.0-1.2-0.8-0.9-1.21.11.30.51.0-1.8-0.9-0.9
Distance traveled after self-admin2.52.85.50.1-1.6-1.7-1.4-1.7-2.32.1-0.62.1-1.2-1.6-1.9-1.9
Delta time in closed arm before/after self-admin0.40.41.5-0.80.90.60.40.80.3-0.11.20.5-0.0-0.30.50.5
Delta time in open arm before/after self-admin0.40.41.10.7-0.9-0.7-0.5-1.0-0.50.4-0.1-0.20.4-0.4-0.9-0.7
Diff in mean of infusions in LGA sessions0.30.40.80.0-0.7-0.6-0.9-0.6-0.50.70.40.8-0.2-0.7-0.6-0.8
Extinction: sum of active levers before priming0.60.72.11.0-0.4-0.8-0.6-0.6-0.70.71.00.60.9-1.5-0.5-0.6
Active lever presses in extinction session 60.10.10.4-0.3-0.1-0.3-0.1-0.2-0.40.5-0.50.6-0.1-0.4-0.3-0.3
Delta distance traveled before/after self-admin1.01.14.9-1.50.10.3-0.1-0.0-0.50.3-1.91.4-2.20.8-0.2-0.2
Delta ambulatory time before/after self-admin1.31.46.0-1.4-0.3-0.1-0.5-0.4-1.00.8-1.92.0-2.50.3-0.7-0.7
Time in closed arm before self-admin3.74.27.61.8-2.7-2.8-1.7-2.7-2.32.2-0.50.11.0-1.7-2.5-2.5
Time in closed arm after self-admin0.20.31.2-1.1-0.0-0.30.2-0.1-0.50.8-0.40.6-0.5-0.2-0.5-0.3
Time in open arm before self-admin1.21.22.2-0.51.11.50.51.41.3-1.50.6-0.6-0.41.31.51.2
Time in open arm after self-admin0.50.52.60.50.00.40.30.10.9-1.00.7-1.60.80.80.50.5
Sum of active levers in priming session hrs 5-60.30.30.60.8-0.6-0.6-0.4-0.7-0.50.5-0.10.10.2-0.6-0.7-0.6
Time to tail flick, vehicle, before self-admin0.20.20.7-0.5-0.10.0-0.4-0.2-0.10.2-0.40.9-0.60.3-0.3-0.3
Time to tail flick, vehicle, after self-admin0.10.10.50.4-0.20.2-0.3-0.20.3-0.4-0.7-0.50.20.70.0-0.0
Time to tail flick, test, before self-admin0.20.20.90.40.20.2-0.10.30.2-0.20.50.31.0-0.20.40.2
Time to tail flick, test, after self-admin0.70.72.21.0-1.0-0.6-0.9-1.0-0.10.00.8-0.91.5-0.2-0.5-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.90.9-0.5-0.5-0.2-0.5-0.40.4-0.2-0.40.4-0.6-0.4-0.4
Delta time to tail flick, test, before/after SA1.00.92.61.2-1.2-0.6-0.9-1.20.1-0.20.7-1.61.30.3-0.6-0.8
Ambulatory time before self-admin0.90.91.71.3-0.9-1.0-1.0-0.9-0.70.61.3-0.21.3-1.2-0.7-0.8
Ambulatory time after self-admin2.22.54.50.9-1.8-1.6-1.8-1.9-2.11.6-0.21.6-0.6-1.4-1.8-1.9
Total heroin consumption0.10.20.80.3-0.1-0.4-0.5-0.1-0.40.50.20.50.2-0.9-0.0-0.3
Area under the delay curve2.02.14.21.5-1.3-1.4-1.8-1.4-1.41.21.90.71.2-2.0-1.1-1.4
Delay disc. indifference point, 0s delay0.40.41.1-0.10.0-0.60.5-0.2-0.81.1-0.90.6-0.8-0.8-0.6-0.3
Delay disc. indifference point, 16s delay3.03.05.71.8-1.8-1.8-2.4-1.9-1.81.22.00.91.1-2.1-1.4-1.8
Delay disc. indifference point, 2s delay1.51.75.81.7-0.9-1.2-1.0-0.8-1.31.21.70.91.2-2.4-0.8-0.9
Delay disc. indifference point, 24s delay0.70.72.6-0.2-0.5-0.5-1.6-0.7-0.80.61.21.3-0.1-0.7-0.4-0.9
Delay disc. indifference point, 4s delay1.61.74.11.1-1.2-1.5-1.4-1.2-1.51.50.81.10.5-2.0-1.1-1.3
Delay disc. indifference point, 8s delay2.12.25.01.4-1.6-1.3-2.0-1.6-1.20.92.20.31.2-1.6-1.3-1.5
Delay discount exponential model param2.02.14.1-1.61.31.41.81.41.3-1.1-2.0-0.6-1.32.01.01.4
Delay discount hyperbolic model param2.12.24.7-1.71.31.41.71.41.4-1.2-2.0-0.7-1.22.21.01.4
Fecal boli incidents, locomotor time 12.22.43.8-0.2-1.7-1.7-1.6-1.7-1.81.9-0.41.9-0.6-1.5-1.8-1.9
Change in fecal boli incidents, locomotor task2.01.93.3-0.91.71.80.71.61.7-1.7-0.0-0.7-0.21.51.81.5
Time >=10cm from walls, locomotor time 10.60.62.7-0.8-0.1-0.30.00.0-0.80.8-1.21.3-1.6-0.3-0.4-0.3
Bouts of movement, locomotor time 10.70.81.6-1.21.30.90.81.20.7-0.4-0.80.4-0.80.51.00.9
Total resting periods, locomotor time 10.30.30.8-0.90.70.40.30.70.10.1-0.60.6-0.7-0.10.40.3
Rest time, locomotor task time 10.40.51.6-1.0-0.0-0.3-0.2-0.1-0.60.9-0.71.1-1.3-0.4-0.5-0.4
Distance moved, locomotor task time 10.91.01.6-0.31.01.11.21.01.1-1.20.0-1.10.31.11.01.2
Vertical activity count, locomotor time 10.20.31.0-0.9-0.20.10.3-0.10.3-0.1-1.0-0.4-0.60.8-0.1-0.0
Time >=10cm from walls, locomotor time 20.50.52.1-0.7-0.5-0.5-0.4-0.4-0.60.6-1.50.4-1.20.0-0.5-0.6
Bouts of movement, locomotor time 20.40.41.2-0.21.00.41.10.70.6-0.40.6-0.60.7-0.10.60.8
Total resting periods, locomotor time 20.20.20.70.00.60.00.60.30.20.10.8-0.20.7-0.60.20.4
Rest time, locomotor task time 20.30.41.20.0-0.6-0.5-0.9-0.5-0.80.60.51.1-0.3-0.6-0.4-0.6
Distance moved, locomotor task time 20.80.91.6-0.41.01.01.31.20.9-0.9-0.9-0.8-0.41.11.01.2
Vertical activity count, locomotor time 20.50.62.3-1.40.30.30.60.30.30.0-1.5-0.1-1.30.70.10.2
Weight adjusted by age0.50.61.5-0.30.51.00.10.70.8-1.10.5-0.7-0.01.20.90.8
Seeking ratio, delayed vs. immediate footshock0.30.42.01.1-0.4-0.4-0.3-0.6-0.1-0.00.1-0.91.4-0.2-0.3-0.4
Locomotion in novel chamber1.92.46.92.2-0.70.3-0.8-0.61.3-1.62.2-2.62.61.20.30.1
Locomotion in novel chamber post-restriction0.70.83.41.7-0.3-0.3-0.3-0.30.1-0.21.5-0.71.9-0.7-0.1-0.1
Progressive ratio0.70.81.40.4-1.1-1.0-0.9-1.1-1.11.0-0.50.7-0.3-0.9-1.1-1.2
Food seeking constrained by brief footshock0.10.10.3-0.40.50.10.30.5-0.10.30.10.4-0.2-0.50.30.2
Seeking ratio, punishment vs. effort0.10.20.5-0.40.70.40.40.70.3-0.20.50.00.1-0.10.50.6
Run reversals in cocaine runway, females0.60.61.8-0.40.30.70.50.21.0-1.20.1-1.10.21.30.60.7
Run reversals in cocaine runway, males0.50.51.60.00.81.0-0.31.00.5-0.61.30.8-0.1-0.00.90.6
Latency to leave start box in cocaine runway1.41.53.5-0.21.71.31.91.61.1-1.1-0.8-0.6-0.10.91.21.7
Latency to leave start box in cocaine runway, F0.30.31.41.20.60.20.70.50.2-0.4-0.1-0.60.8-0.30.40.6
Latency to leave start box in cocaine runway, M2.82.75.4-1.62.01.82.32.01.5-1.3-1.0-0.3-0.91.71.52.1
Cd content in liver0.60.71.80.50.40.90.50.51.4-0.91.4-1.20.50.70.60.6
Co content in liver0.20.20.50.6-0.5-0.2-0.5-0.5-0.10.40.7-0.1-0.1-0.5-0.4-0.7
Cu content in liver2.12.59.03.0-1.7-1.5-1.5-1.6-0.80.61.0-1.02.6-1.3-0.7-1.4
Fe content in liver0.70.94.6-0.90.20.11.00.1-0.20.1-2.2-0.1-1.91.00.10.2
K content in liver0.50.51.20.5-0.8-0.9-0.5-0.6-1.10.7-0.70.60.1-0.8-0.6-0.5
Mg content in liver0.80.81.90.6-1.0-1.2-0.3-0.9-1.41.0-1.30.7-0.2-0.9-0.8-0.8
Mn content in liver0.60.71.30.11.00.90.70.90.9-1.10.3-0.60.80.51.21.1
Na content in liver0.80.92.11.2-1.3-1.1-0.9-1.4-0.70.50.2-0.30.8-0.4-1.1-1.1
Rb content in liver0.20.20.40.3-0.4-0.5-0.5-0.4-0.60.6-0.30.5-0.0-0.6-0.2-0.5
Se content in liver1.41.74.11.70.20.80.40.41.3-1.62.0-2.01.81.01.20.8
Sr content in liver1.91.86.62.3-0.8-0.1-1.2-0.60.5-0.62.4-1.32.6-0.5-0.2-0.4
Zn content in liver0.50.51.71.3-0.8-0.6-0.6-0.7-0.40.01.1-0.51.0-0.3-0.3-0.4