Hub : Genes

AABR07007068.1

Models

#	tissue	modality	RNA phenotype	h²	h² se	h² P	eQTL R²	BLUP R²	ENET R²	LASSO R²	eQTL P	BLUP P	ENET P	LASSO P
1	Adipose	isoform ratio	ENSRNOT00000104357	0.1300	0.0630	8.4e-11	0.086	0.080	0.078	0.083	8.3e-10	3.6e-09	4.9e-09	1.5e-09
2	Adipose	isoform ratio	ENSRNOT00000119102	0.1200	0.0620	1.4e-08	0.072	0.063	0.070	0.075	2.2e-08	1.7e-07	3.3e-08	1.1e-08
3	Adipose	mRNA stability	ENSRNOG00000017438	0.0630	0.0420	3.3e-04	0.024	0.019	0.034	0.032	1.1e-03	3.3e-03	1.0e-04	1.6e-04
4	BLA	isoform ratio	ENSRNOT00000104357	0.1700	0.1100	2.2e-03	0.039	0.024	0.026	0.036	3.5e-03	1.8e-02	1.6e-02	5.1e-03
5	BLA	isoform ratio	ENSRNOT00000119102	0.2000	0.1300	2.2e-03	0.040	0.024	0.021	0.035	3.4e-03	1.9e-02	2.5e-02	5.4e-03
6	BLA	intron excision ratio	chr1:257550780:257551332	0.0680	0.0500	7.9e-03	0.028	0.022	0.025	0.026	1.2e-02	2.2e-02	1.7e-02	1.4e-02
7	BLA	intron excision ratio	chr1:257550780:257551377	0.1200	0.0730	1.9e-04	0.060	0.045	0.026	0.044	3.7e-04	1.9e-03	1.5e-02	2.1e-03
8	Brain	gene expression	ENSRNOG00000017438	0.0830	0.0460	1.1e-07	0.056	0.072	0.072	0.040	6.7e-06	3.2e-07	3.1e-07	1.3e-04
9	Brain	isoform ratio	ENSRNOT00000104357	0.2222	0.0895	5.6e-17	0.188	0.155	0.168	0.182	3.6e-17	3.1e-14	2.2e-15	1.1e-16
10	Brain	isoform ratio	ENSRNOT00000119102	0.2234	0.0891	0.0e+00	0.185	0.162	0.167	0.187	5.9e-17	6.8e-15	2.9e-15	4.1e-17
11	Brain	intron excision ratio	chr1:257550780:257551332	0.0455	0.0298	1.5e-03	0.037	0.022	0.027	0.032	2.3e-04	3.9e-03	1.3e-03	5.6e-04
12	Brain	intron excision ratio	chr1:257550780:257551377	0.0585	0.0333	6.6e-06	0.020	0.047	0.027	0.028	5.1e-03	3.7e-05	1.4e-03	1.1e-03
13	IL	gene expression	ENSRNOG00000017438	0.2210	0.1230	1.6e-03	0.032	0.095	0.075	0.061	5.8e-02	2.8e-03	7.5e-03	1.5e-02
14	LHb	gene expression	ENSRNOG00000017438	0.1986	0.1155	2.7e-03	0.079	0.044	0.015	0.026	6.4e-03	3.3e-02	1.4e-01	8.1e-02
15	Liver	gene expression	ENSRNOG00000017438	0.5000	0.1400	0.0e+00	0.368	0.381	0.384	0.388	8.6e-43	1.1e-44	4.4e-45	1.2e-45
16	Liver	isoform ratio	ENSRNOT00000104357	0.5139	0.1153	0.0e+00	0.379	0.347	0.377	0.375	2.7e-44	6.5e-40	4.8e-44	9.6e-44
17	Liver	isoform ratio	ENSRNOT00000119102	0.5139	0.1152	0.0e+00	0.394	0.356	0.387	0.389	1.5e-46	4.2e-41	1.5e-45	9.3e-46
18	Liver	intron excision ratio	chr1:257424808:257487815	0.0319	0.0245	4.0e-03	0.010	0.018	0.010	0.010	2.3e-02	3.6e-03	2.4e-02	2.3e-02
19	Liver	intron excision ratio	chr1:257550780:257551633	0.0232	0.0173	4.2e-03	0.011	0.013	0.003	0.000	1.9e-02	1.1e-02	1.4e-01	2.7e-01
20	Liver	mRNA stability	ENSRNOG00000017438	0.0760	0.0471	2.4e-04	0.034	0.023	0.024	0.030	1.0e-04	1.3e-03	8.9e-04	2.6e-04
21	NAcc	gene expression	ENSRNOG00000017438	0.0590	0.0430	3.2e-03	0.036	0.019	0.026	0.035	1.1e-03	1.3e-02	4.6e-03	1.2e-03
22	PL	gene expression	ENSRNOG00000017438	0.3914	0.1603	3.3e-11	0.149	0.092	0.128	0.128	2.0e-11	1.8e-07	6.1e-10	5.8e-10
23	PL	isoform ratio	ENSRNOT00000104357	0.1100	0.0620	1.8e-05	0.056	0.048	0.037	0.044	4.5e-05	1.6e-04	8.4e-04	2.9e-04
24	PL	isoform ratio	ENSRNOT00000119102	0.0840	0.0520	2.2e-04	0.021	0.026	0.011	0.017	9.4e-03	4.0e-03	4.2e-02	1.6e-02

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method.

Trait associations

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Bone: periosteal perimeter	8.1	13.4	23.5	4.8	-4.8	-0.8	4.8	-4.8	2.0	-2.0	-3.3	4.8	-4.5	1.9	-0.9	-3.2	-4.8	-0.5	4.8	-4.8	-2.2	-1.9	3.3	2.0	-4.8	4.8	-3.4
Weight adjusted by age	6.8	7.7	14.9	3.7	-3.5	-2.0	3.7	-3.7	0.8	-0.8	-2.7	3.5	-3.3	0.7	-0.0	-2.3	-3.7	-0.7	3.5	-3.7	-2.0	-1.7	2.8	0.8	-3.9	3.8	-2.1
Retroperitoneal fat weight	6.3	20.9	37.0	5.7	-5.7	-0.5	5.9	-5.9	3.4	-3.4	-3.3	5.7	-5.3	4.3	-3.3	-3.8	-6.0	0.2	5.7	-6.1	-1.2	-1.2	3.3	3.4	-5.8	6.0	-5.1
Parametrial fat weight	6.0	11.8	18.4	4.3	-4.3	-0.4	4.1	-4.1	3.6	-3.6	-2.1	4.3	-3.9	3.5	-3.2	-2.5	-4.2	0.7	4.3	-4.2	-0.2	-0.3	1.7	3.6	-4.2	4.2	-3.9
Delay disc. indifference point, 8s delay	5.0	5.2	9.1	2.7	-3.0	-1.0	3.0	-3.0	0.8	-0.8	-2.4	3.0	-3.0	0.6	0.0	-2.4	-2.8	-1.4	3.0	-2.8	-1.8	-1.8	2.0	0.8	-2.7	2.9	-2.4
BMI with tail	4.9	15.9	27.4	5.1	-5.0	1.0	5.2	-5.2	2.3	-2.3	-3.7	5.0	-4.8	2.9	-1.8	-3.7	-5.2	-0.9	5.0	-5.2	-1.9	-1.9	3.4	2.3	-5.1	5.1	-4.5
Epididymis fat weight	4.8	11.1	17.9	4.0	-4.2	-0.2	4.2	-4.2	3.0	-3.0	-1.9	4.2	-3.9	4.1	-3.2	-2.6	-4.0	0.5	4.2	-4.0	-0.3	-0.3	1.9	3.0	-4.0	4.0	-3.9
Bone: cortical area	4.5	6.9	12.7	3.4	-3.6	-0.6	3.5	-3.5	2.1	-2.1	-1.6	3.6	-3.0	1.9	-1.4	-1.4	-3.4	1.3	3.6	-3.5	-0.8	-0.3	2.0	2.1	-3.5	3.5	-1.7
Body weight	4.3	18.2	30.0	5.4	-5.5	-0.1	5.4	-5.4	2.7	-2.7	-4.0	5.5	-5.3	3.3	-2.3	-4.1	-5.3	-1.3	5.5	-5.4	-1.8	-2.0	3.2	2.7	-5.4	5.3	-5.1
Delay discounting total patch changes 18 sec	4.3	5.6	9.3	2.9	-3.0	-0.6	3.0	-3.0	2.2	-2.2	-1.6	3.0	-2.9	2.5	-1.7	-1.7	-3.0	0.3	3.0	-2.9	-0.5	-0.4	1.6	2.2	-2.9	2.9	-2.4
Delay discounting total patch changes 6 sec	4.3	6.6	12.5	3.5	-3.3	-0.2	3.4	-3.4	2.1	-2.1	-1.7	3.3	-2.9	2.1	-1.6	-1.5	-3.4	0.9	3.3	-3.4	-0.7	-0.3	1.9	2.1	-3.4	3.5	-2.0
Cocaine induced anxiety	4.3	4.9	8.2	-2.6	2.8	1.2	-2.6	2.6	-1.8	1.8	2.1	-2.8	2.8	-1.6	1.1	2.3	2.7	1.2	-2.8	2.7	1.0	1.2	-1.4	-1.8	2.7	-2.6	2.9
Bone: maximum diameter	4.3	7.8	13.4	3.6	-3.6	-0.0	3.6	-3.6	2.6	-2.6	-2.0	3.6	-3.2	2.5	-1.9	-2.0	-3.5	0.4	3.6	-3.6	-0.7	-0.5	1.7	2.6	-3.7	3.6	-2.8
Change in fecal boli incidents, locomotor task	4.2	4.0	7.2	-2.3	2.5	2.0	-2.4	2.4	0.2	-0.2	2.2	-2.5	2.3	0.2	-0.8	1.8	2.7	1.3	-2.5	2.7	2.0	1.7	-2.5	0.2	2.4	-2.6	1.3
Delay discounting total patch changes 24 sec	4.1	5.1	8.9	2.8	-3.0	-1.6	2.8	-2.8	2.3	-2.3	-1.5	3.0	-2.7	2.2	-1.8	-1.4	-2.7	0.3	3.0	-2.7	-0.3	-0.2	1.1	2.3	-2.8	2.7	-2.2
Baseline Anxiety	4.1	4.4	6.9	2.5	-2.6	-0.5	2.5	-2.5	2.0	-2.0	-1.5	2.6	-2.5	2.1	-1.6	-1.7	-2.5	-0.3	2.6	-2.5	-0.4	-0.5	1.1	2.0	-2.5	2.5	-2.5
Progressive ratio test 2 active lever presses	4.0	4.3	7.7	2.6	-2.2	0.0	2.6	-2.6	-0.6	0.6	-2.4	2.2	-2.2	-0.2	0.8	-2.4	-2.6	-1.4	2.2	-2.6	-2.2	-2.1	2.8	-0.6	-2.7	2.6	-1.9
Incentive Sensitization - Responses	3.9	3.9	6.4	2.3	-2.2	-0.9	2.4	-2.4	0.0	-0.0	-2.3	2.2	-2.4	0.4	0.1	-2.5	-2.4	-1.6	2.2	-2.4	-1.7	-1.9	2.1	0.0	-2.4	2.4	-2.5
Progressive ratio test 2 breakpoint	3.8	4.2	6.9	2.6	-2.3	-0.2	2.5	-2.5	-0.5	0.5	-2.4	2.3	-2.3	-0.1	0.7	-2.5	-2.5	-1.6	2.3	-2.5	-2.1	-2.2	2.6	-0.5	-2.6	2.5	-2.1
Time in open arm before self-admin	3.8	4.0	6.9	-2.5	2.6	0.7	-2.4	2.4	0.1	-0.1	1.9	-2.6	2.5	-0.2	-0.3	2.3	2.5	1.0	-2.6	2.5	1.8	1.8	-2.3	0.1	2.6	-2.5	2.0
Liver weight, right	3.7	6.1	10.3	3.1	-3.1	1.0	3.0	-3.0	1.4	-1.4	-2.4	3.1	-3.1	2.0	-1.1	-2.7	-3.0	-1.1	3.1	-3.0	-1.3	-1.5	2.1	1.4	-3.0	3.0	-3.2
Incentive Sensitization - Breakpoint	3.7	3.7	6.3	2.3	-2.3	-0.7	2.4	-2.4	0.2	-0.2	-2.1	2.3	-2.4	0.5	-0.1	-2.5	-2.4	-1.5	2.3	-2.4	-1.6	-1.8	2.0	0.2	-2.4	2.3	-2.5
Bone: endosteal perimeter	3.7	7.6	13.1	3.5	-3.6	-1.3	3.6	-3.6	1.4	-1.4	-2.4	3.6	-3.4	1.3	-0.6	-2.7	-3.5	-0.8	3.6	-3.5	-1.8	-1.7	2.4	1.4	-3.6	3.5	-2.9
Soleus weight	3.5	10.1	19.5	3.4	-3.4	-1.7	3.4	-3.4	-0.2	0.2	-4.1	3.4	-3.7	-0.1	1.2	-4.4	-3.5	-3.8	3.4	-3.5	-3.4	-3.9	3.5	-0.2	-3.5	3.5	-4.0
Intermittent access day 15 total locomotion	3.2	3.4	6.2	2.5	-2.3	-0.7	2.5	-2.5	0.5	-0.5	-1.9	2.3	-2.3	1.1	-0.4	-1.9	-2.4	-0.8	2.3	-2.4	-1.2	-1.2	1.8	0.5	-2.4	2.2	-2.0
Bone: trabecular thickness	3.2	3.8	6.4	2.5	-2.5	-0.7	2.5	-2.5	1.8	-1.8	-1.5	2.5	-2.3	1.4	-1.3	-1.4	-2.5	-0.0	2.5	-2.5	-0.5	-0.5	1.2	1.8	-2.5	2.5	-2.0
Total sessions with >9 infusions	3.1	3.4	8.1	2.4	-1.9	-1.3	2.1	-2.1	-1.2	1.2	-2.1	1.9	-1.7	-0.9	1.6	-1.5	-2.2	-0.7	1.9	-2.2	-2.3	-1.8	2.8	-1.2	-2.5	2.2	-0.5
Locomotion velocity, session 8	3.1	3.7	6.0	-2.1	2.3	0.1	-2.3	2.3	-0.8	0.8	2.3	-2.3	2.4	-0.8	0.0	2.3	2.4	1.7	-2.3	2.4	1.5	1.8	-1.7	-0.8	2.3	-2.4	2.4
Time >=10cm from walls, locomotor time 1	3.1	3.1	6.4	-2.5	2.3	0.1	-1.9	1.9	-0.1	0.1	2.0	-2.3	2.2	-0.5	-0.4	1.8	2.3	1.0	-2.3	2.3	1.6	1.5	-1.9	-0.1	2.5	-2.4	1.5
Incentive salience index mean	3.0	3.6	6.0	-2.2	2.4	1.6	-2.3	2.3	-1.0	1.0	2.0	-2.4	2.4	-0.7	0.2	2.0	2.3	1.4	-2.4	2.2	1.4	1.4	-1.7	-1.0	2.2	-2.2	2.1
Cd content in liver	3.0	3.2	6.8	-1.9	1.9	1.5	-1.9	1.9	-0.4	0.4	2.5	-1.9	2.2	-0.2	-0.3	2.5	1.9	2.6	-1.9	1.9	1.7	2.1	-1.6	-0.4	1.9	-1.9	2.5
Short access total locomotion	2.9	3.0	7.0	1.8	-1.3	-1.3	1.3	-1.3	-1.9	1.9	-2.0	1.3	-1.2	-1.8	2.2	-1.6	-1.6	-1.6	1.3	-1.6	-2.5	-2.2	2.6	-1.9	-1.8	1.4	-0.3
Intermitt. access day 1 inactive lever presses	2.8	3.1	5.4	2.2	-2.0	1.9	2.1	-2.1	1.5	-1.5	-1.3	2.0	-2.0	1.9	-1.6	-1.5	-2.2	-0.2	2.0	-2.2	-0.2	-0.4	0.8	1.5	-1.9	2.0	-2.3
Locomotion distance, session 8	2.7	4.1	10.5	-2.2	2.2	0.4	-2.1	2.1	-1.7	1.7	2.3	-2.2	2.5	-1.6	1.0	2.5	2.3	2.0	-2.2	2.3	0.9	1.5	-1.1	-1.7	2.2	-2.3	3.2
BMI without tail	2.6	5.4	9.1	3.0	-2.8	1.6	2.9	-2.9	1.4	-1.4	-2.2	2.8	-2.8	2.0	-1.4	-2.3	-2.9	-0.7	2.8	-2.8	-0.9	-1.0	1.9	1.4	-2.9	2.8	-2.9
Delay discounting total patch changes 0 sec	2.6	4.2	7.7	2.7	-2.8	-1.5	2.7	-2.7	1.6	-1.6	-1.4	2.8	-2.4	1.8	-1.1	-1.3	-2.6	0.4	2.8	-2.6	-0.7	-0.3	1.4	1.6	-2.6	2.6	-1.6
Social responses	2.6	3.3	6.4	2.3	-2.5	1.0	2.5	-2.5	1.0	-1.0	-1.3	2.5	-2.2	0.8	-0.5	-1.5	-2.4	0.1	2.5	-2.4	-1.0	-0.8	1.6	1.0	-2.1	2.4	-1.5
Glucose	2.5	3.9	7.3	2.7	-2.4	0.2	2.6	-2.6	1.4	-1.4	-1.8	2.4	-2.3	1.7	-1.1	-1.9	-2.4	-0.5	2.4	-2.4	-0.8	-0.9	1.4	1.4	-2.5	2.4	-2.4
Intermittent access intake escalation	2.5	2.5	4.4	2.1	-1.9	0.6	2.0	-2.0	-0.4	0.4	-1.8	1.9	-1.8	-0.1	0.7	-1.8	-1.9	-1.1	1.9	-1.9	-1.7	-1.6	2.0	-0.4	-1.9	1.9	-1.4
Condit. Reinf. active minus inactive responses	2.5	2.8	4.9	-1.8	2.2	1.3	-2.0	2.0	-0.5	0.5	1.9	-2.2	2.2	-0.4	-0.2	1.9	2.0	1.5	-2.2	1.9	1.5	1.5	-1.7	-0.5	1.9	-1.9	1.8
Bone: periosteal estimation	2.5	5.1	9.2	2.9	-3.0	-0.4	3.0	-3.0	1.9	-1.9	-1.4	3.0	-2.6	1.6	-1.3	-1.3	-2.9	0.8	3.0	-3.0	-0.7	-0.3	1.6	1.9	-3.0	3.0	-1.7
Right kidney weight	2.4	6.9	14.6	2.7	-3.3	-1.6	3.0	-3.0	-1.9	1.9	-2.5	3.3	-2.8	-1.6	2.1	-2.3	-2.8	-1.0	3.3	-3.0	-3.3	-2.6	3.8	-1.9	-2.9	3.0	-0.8
Latency to leave start box in cocaine runway, M	2.4	2.3	4.7	2.2	-1.6	-1.6	1.6	-1.6	0.0	-0.0	-2.0	1.6	-1.6	-0.1	0.6	-1.6	-1.9	-1.6	1.6	-1.9	-1.5	-1.5	1.6	0.0	-2.0	1.9	-1.3
Locomotion in novel chamber post-restriction	2.3	2.8	4.9	-1.6	1.9	1.6	-1.9	1.9	-2.2	2.2	0.5	-1.9	1.7	-1.8	1.9	0.7	1.9	-0.7	-1.9	2.0	-0.4	-0.3	-0.2	-2.2	1.8	-1.8	1.6
Indifference point 0 sec	2.2	3.6	6.8	2.5	-2.6	-1.3	2.5	-2.5	1.4	-1.4	-1.3	2.6	-2.3	1.6	-1.0	-1.2	-2.3	0.4	2.6	-2.4	-0.7	-0.4	1.3	1.4	-2.4	2.4	-1.5
Reaction time mean minus median AUC	2.2	2.8	6.1	2.0	-1.4	0.2	1.7	-1.7	-0.6	0.6	-2.5	1.4	-1.6	-0.6	0.9	-2.5	-1.7	-2.4	1.4	-1.8	-1.9	-2.3	1.9	-0.6	-1.8	1.8	-2.1
Std. dev. reaction times	2.2	3.0	5.6	2.3	-1.8	0.4	2.0	-2.0	0.4	-0.4	-2.2	1.8	-1.9	0.4	-0.1	-2.2	-2.1	-1.6	1.8	-2.1	-1.3	-1.6	1.6	0.4	-2.1	2.1	-2.4
One hour access (shock baseline)	2.2	2.6	4.6	2.0	-2.1	0.8	2.2	-2.2	-0.5	0.5	-1.5	2.1	-1.9	-0.2	0.6	-1.6	-2.0	-0.6	2.1	-2.0	-1.6	-1.4	2.0	-0.5	-2.0	1.9	-1.1
Liver weight, left	2.1	3.4	6.4	2.1	-2.4	0.4	2.3	-2.3	1.4	-1.4	-1.5	2.4	-2.3	1.7	-1.2	-2.0	-2.2	-0.6	2.4	-2.2	-0.7	-0.9	1.2	1.4	-2.1	2.1	-2.5
Intermittent access intake day 1-15 change	2.1	2.1	3.8	1.9	-1.8	0.6	1.8	-1.8	0.7	-0.7	-1.4	1.8	-1.8	0.8	-0.5	-1.6	-1.8	-0.8	1.8	-1.8	-0.8	-1.0	1.1	0.7	-1.7	1.7	-1.8
Bone: minimum diameter	2.1	3.8	6.6	2.4	-2.6	0.3	2.5	-2.5	1.9	-1.9	-1.2	2.6	-2.3	1.6	-1.3	-1.2	-2.5	0.7	2.6	-2.5	-0.4	-0.2	1.1	1.9	-2.6	2.5	-1.7
Delta time to tail flick, test, before/after SA	2.1	1.8	3.6	1.1	-1.5	-0.2	1.5	-1.5	1.9	-1.9	-0.2	1.5	-1.4	1.9	-1.8	-0.4	-1.5	1.0	1.5	-1.5	0.5	0.5	0.2	1.9	-1.6	1.5	-1.3
Delay discounting total patch changes 12 sec	2.0	2.6	4.4	2.1	-2.1	0.0	2.0	-2.0	1.5	-1.5	-0.9	2.1	-1.9	1.9	-1.4	-0.9	-2.0	0.6	2.1	-2.0	-0.1	0.0	0.9	1.5	-2.0	2.1	-1.5
Light reinforcement 2	2.0	2.7	4.5	-2.0	2.0	2.1	-2.1	2.1	-1.3	1.3	1.5	-2.0	1.9	-0.9	0.7	1.4	2.0	0.6	-2.0	2.0	0.7	0.7	-1.1	-1.3	1.9	-2.0	1.8
Reaction time trials on left	2.0	2.8	4.7	2.1	-1.9	-0.6	2.0	-2.0	0.7	-0.7	-2.0	1.9	-2.0	0.9	-0.2	-1.9	-2.1	-1.3	1.9	-2.1	-1.2	-1.4	1.4	0.7	-2.2	2.1	-2.0
Reaction time trials completed	2.0	2.8	4.7	2.1	-1.9	-0.6	2.0	-2.0	0.7	-0.7	-2.0	1.9	-2.0	0.9	-0.2	-1.9	-2.1	-1.3	1.9	-2.1	-1.2	-1.4	1.4	0.7	-2.2	2.1	-2.0
Intermittent access total locomotion	2.0	2.2	5.5	1.6	-1.3	-0.4	1.4	-1.4	-1.5	1.5	-1.6	1.3	-1.2	-0.9	1.5	-1.6	-1.6	-1.1	1.3	-1.6	-2.0	-1.8	2.3	-1.5	-1.6	1.4	-0.7
Intraocular pressure	1.9	2.7	4.3	2.0	-2.0	-0.9	1.8	-1.8	2.0	-2.0	-0.7	2.0	-1.7	1.9	-1.8	-0.5	-2.1	1.0	2.0	-2.1	0.3	0.5	0.6	2.0	-2.0	2.1	-1.3
Indifference point AUC	1.9	2.3	4.3	2.0	-1.9	0.5	1.8	-1.8	1.0	-1.0	-1.4	1.9	-1.8	1.1	-0.7	-1.2	-2.0	-0.2	1.9	-2.0	-0.6	-0.5	1.4	1.0	-2.1	2.0	-1.5
Reaction time trials AUC	1.9	2.7	4.5	2.1	-1.9	-0.7	2.0	-2.0	0.7	-0.7	-1.9	1.9	-2.0	0.8	-0.2	-1.9	-2.1	-1.2	1.9	-2.1	-1.2	-1.3	1.4	0.7	-2.1	2.1	-2.0
Condit. Reinf. active responses	1.9	2.6	6.6	1.6	-1.6	-0.3	1.5	-1.5	2.6	-2.6	-0.4	1.6	-1.5	2.4	-2.2	-0.6	-1.6	0.9	1.6	-1.6	0.7	0.6	-0.0	2.6	-1.6	1.6	-1.6
Diff in mean of infusions in LGA sessions	1.9	2.1	10.8	-1.1	1.3	3.3	-1.6	1.6	1.2	-1.2	0.9	-1.3	1.1	1.2	-1.6	0.8	1.4	0.3	-1.3	1.5	1.8	1.3	-2.1	1.2	1.3	-1.5	-0.2
Reaction time number correct	1.8	2.5	4.3	2.0	-1.8	-0.6	1.9	-1.9	0.7	-0.7	-1.9	1.8	-1.9	0.9	-0.1	-1.8	-2.0	-1.2	1.8	-2.0	-1.2	-1.3	1.4	0.7	-2.1	2.0	-1.9
Reaction time trials correct on left	1.8	2.5	4.3	2.0	-1.8	-0.6	1.9	-1.9	0.7	-0.7	-1.9	1.8	-1.9	0.9	-0.1	-1.8	-2.0	-1.2	1.8	-2.0	-1.2	-1.3	1.4	0.7	-2.1	2.0	-1.9
Social time	1.8	2.3	5.7	1.6	-1.4	-1.2	1.3	-1.3	-0.5	0.5	-2.1	1.4	-1.6	-0.6	1.1	-2.1	-1.4	-2.4	1.4	-1.4	-1.9	-2.1	1.7	-0.5	-1.5	1.5	-1.7
Bone: final force	1.8	2.9	6.4	2.4	-2.2	-0.2	2.4	-2.4	0.6	-0.6	-1.3	2.2	-1.8	0.8	-0.5	-1.0	-2.5	0.8	2.2	-2.5	-0.9	-0.4	1.8	0.6	-2.5	2.5	-0.9
Cocaine response after cond. corrected	1.7	1.9	6.7	-0.8	1.0	0.2	-1.0	1.0	-2.4	2.4	-0.2	-1.0	0.9	-2.6	2.4	0.3	1.0	-1.0	-1.0	1.0	-1.1	-0.9	0.5	-2.4	0.9	-0.9	1.5
Intermittent access total infusions	1.7	1.9	4.4	1.9	-1.3	0.7	1.6	-1.6	-0.8	0.8	-1.5	1.3	-1.2	-0.5	0.8	-1.4	-1.7	-0.7	1.3	-1.7	-1.5	-1.4	2.1	-0.8	-1.8	1.7	-0.8
Bone: cortical thickness	1.7	2.7	5.5	2.2	-2.3	-1.2	2.2	-2.2	0.8	-0.8	-1.0	2.3	-1.8	0.6	-0.4	-0.5	-2.2	1.4	2.3	-2.3	-0.8	-0.1	1.7	0.8	-2.2	2.3	-0.3
Bone: final moment	1.7	2.9	6.1	2.4	-2.1	-0.1	2.4	-2.4	0.7	-0.7	-1.3	2.1	-1.8	0.9	-0.6	-1.0	-2.4	0.8	2.1	-2.5	-0.8	-0.4	1.7	0.7	-2.5	2.5	-1.0
Delay discount exponential model param	1.7	1.8	4.0	-1.4	1.6	-0.1	-1.6	1.6	-0.5	0.5	1.7	-1.6	1.7	-0.4	0.1	1.8	1.3	1.7	-1.6	1.3	1.0	1.3	-0.8	-0.5	1.3	-1.4	2.0
Food consumed during 24 hour testing period	1.6	2.0	5.8	-1.4	1.6	2.4	-1.7	1.7	-0.3	0.3	1.3	-1.6	1.6	-0.2	-0.0	1.4	1.8	0.9	-1.6	1.8	1.1	1.1	-1.4	-0.3	1.6	-1.8	1.4
Intermittent access day 15 total infusions	1.6	1.8	3.6	1.8	-1.3	0.9	1.5	-1.5	-0.7	0.7	-1.6	1.3	-1.3	-0.3	0.7	-1.6	-1.6	-1.1	1.3	-1.6	-1.5	-1.5	1.9	-0.7	-1.7	1.5	-1.2
Lifetime Intake	1.6	1.7	4.3	1.9	-1.3	-0.1	1.6	-1.6	-0.8	0.8	-1.4	1.3	-1.1	-0.5	0.9	-1.1	-1.7	-0.5	1.3	-1.7	-1.5	-1.2	2.1	-0.8	-1.9	1.7	-0.5
Condit. Reinf. active responses	1.6	2.0	3.7	-1.4	1.5	1.4	-1.5	1.5	0.2	-0.2	1.8	-1.5	1.7	0.2	-0.8	1.8	1.5	1.9	-1.5	1.3	1.6	1.8	-1.6	0.2	1.3	-1.3	1.5
Time to tail flick, test, after self-admin	1.6	1.6	3.0	1.6	-1.6	-1.2	1.7	-1.7	1.0	-1.0	-0.6	1.6	-1.5	1.1	-1.0	-0.9	-1.7	0.6	1.6	-1.6	-0.2	-0.2	0.8	1.0	-1.7	1.6	-1.2
Area under the delay curve	1.6	1.7	3.7	1.4	-1.5	-0.2	1.6	-1.6	0.6	-0.6	-1.6	1.5	-1.7	0.5	-0.1	-1.7	-1.3	-1.6	1.5	-1.3	-0.9	-1.3	0.8	0.6	-1.3	1.4	-1.9
Cocaine response after cond. not corrected	1.5	1.6	4.8	-1.0	1.1	0.2	-1.2	1.2	-2.0	2.0	0.1	-1.1	1.1	-2.2	2.0	0.6	1.2	-0.7	-1.1	1.2	-0.7	-0.5	0.1	-2.0	1.1	-1.1	1.6
Bone: cortical tissue density	1.5	2.0	6.9	-0.6	1.0	0.8	-0.8	0.8	-2.6	2.6	-0.4	-1.0	0.9	-2.6	2.5	0.1	0.7	-0.9	-1.0	0.6	-1.3	-1.1	0.9	-2.6	0.7	-0.6	1.4
Bone: post-yield work	1.5	2.0	6.3	-1.0	1.3	2.3	-1.1	1.1	0.6	-0.6	1.9	-1.3	1.5	1.0	-1.4	1.9	0.9	2.5	-1.3	0.8	1.9	2.1	-1.6	0.6	0.9	-0.8	1.4
Time in open arm after self-admin	1.5	1.7	3.6	-0.9	0.9	0.9	-1.1	1.1	1.3	-1.3	1.6	-0.9	0.9	1.5	-1.7	1.3	1.1	1.7	-0.9	1.1	1.9	1.8	-1.9	1.3	0.8	-1.1	0.4
Bouts of movement, locomotor time 1	1.5	1.7	3.4	1.3	-1.8	-0.2	1.8	-1.8	0.6	-0.6	-0.8	1.8	-1.6	0.7	-0.6	-1.3	-1.8	-0.0	1.8	-1.8	-0.6	-0.7	1.2	0.6	-1.5	1.6	-1.6
Heart weight	1.4	2.0	5.1	1.8	-1.8	-2.3	1.6	-1.6	0.5	-0.5	-1.3	1.8	-1.5	0.1	-0.2	-1.0	-1.9	-0.3	1.8	-1.9	-0.8	-0.6	1.5	0.5	-1.9	1.9	-1.0
Std. dev. time between licks in bursts	1.4	1.7	3.4	-1.3	1.2	0.3	-1.4	1.4	0.5	-0.5	1.7	-1.2	1.4	-0.2	-0.8	1.8	1.4	1.7	-1.2	1.4	1.6	1.8	-1.6	0.5	1.2	-1.4	1.5
Condit. Reinf. active minus inactive responses	1.4	1.7	5.2	1.1	-1.1	-0.3	1.1	-1.1	2.3	-2.3	-0.2	1.1	-1.0	2.0	-1.9	-0.3	-1.2	0.8	1.1	-1.2	0.8	0.7	-0.3	2.3	-1.2	1.2	-1.3
Bone: cortical apparent density	1.4	1.8	6.7	-0.3	0.7	0.6	-0.6	0.6	-2.5	2.5	-0.5	-0.7	0.7	-2.6	2.4	-0.0	0.5	-0.8	-0.7	0.4	-1.4	-1.1	1.1	-2.5	0.4	-0.3	1.3
Time to tail flick, test, before self-admin	1.4	1.4	4.7	0.4	-0.1	-2.0	0.0	-0.0	-2.2	2.2	-0.5	0.1	0.2	-2.0	2.0	-0.3	-0.1	-0.3	0.1	-0.1	-1.5	-1.1	1.4	-2.2	-0.0	0.1	0.9
Delay discount hyperbolic model param	1.4	1.5	3.5	-1.3	1.3	0.2	-1.5	1.5	-0.4	0.4	1.6	-1.3	1.5	-0.3	-0.0	1.8	1.1	1.8	-1.3	1.1	1.0	1.4	-0.8	-0.4	1.2	-1.2	1.9
Seeking ratio, delayed vs. immediate footshock	1.4	1.6	3.2	-1.4	1.7	-0.4	-1.7	1.7	-1.2	1.2	1.0	-1.7	1.7	-1.3	0.9	1.3	1.4	0.3	-1.7	1.3	0.3	0.5	-0.5	-1.2	1.2	-1.3	1.8
Reaction time false alarm rate	1.3	1.8	3.3	-1.4	1.7	0.9	-1.5	1.5	-0.6	0.6	1.5	-1.7	1.7	-1.3	0.4	1.6	1.6	1.0	-1.7	1.6	0.8	1.0	-1.1	-0.6	1.5	-1.5	1.8
Condit. Reinf. lever reinforcers received	1.3	1.9	5.0	1.3	-1.3	0.1	1.2	-1.2	2.2	-2.2	-0.1	1.3	-1.1	2.1	-2.0	-0.2	-1.3	1.2	1.3	-1.3	0.8	0.8	-0.1	2.2	-1.4	1.3	-1.2
Condit. Reinf. lever presses	1.3	1.7	2.9	-1.7	1.7	1.2	-1.7	1.7	-0.8	0.8	1.3	-1.7	1.6	-0.5	0.3	1.3	1.6	0.7	-1.7	1.5	0.8	0.8	-1.1	-0.8	1.6	-1.5	1.4
Delta time in open arm before/after self-admin	1.3	1.3	4.2	0.7	-1.0	0.2	0.6	-0.6	1.8	-1.8	0.5	1.0	-0.9	2.1	-2.0	0.0	-0.7	1.3	1.0	-0.7	1.0	0.9	-0.6	1.8	-0.9	0.7	-0.9
Time to tail flick, vehicle, before self-admin	1.3	1.3	2.3	1.1	-1.5	-1.1	1.3	-1.3	1.3	-1.3	-0.2	1.5	-1.1	1.2	-0.9	0.1	-1.4	1.2	1.5	-1.4	0.1	0.5	0.5	1.3	-1.2	1.4	-0.2
Delay discounting water rate 12 sec	1.2	1.8	3.8	1.5	-1.3	-0.8	1.4	-1.4	1.9	-1.9	-0.2	1.3	-1.2	1.9	-1.6	-0.3	-1.5	1.2	1.3	-1.5	0.5	0.6	0.1	1.9	-1.6	1.5	-1.0
Locomotor testing rearing	1.2	2.0	3.4	1.5	-1.5	-0.3	1.4	-1.4	-0.7	0.7	-1.7	1.5	-1.6	-0.7	1.1	-1.8	-1.4	-1.4	1.5	-1.4	-1.8	-1.8	1.8	-0.7	-1.6	1.5	-1.2
Reaction time mean minus median	1.2	1.5	3.1	1.7	-1.2	0.8	1.4	-1.4	0.1	-0.1	-1.6	1.2	-1.3	0.3	-0.1	-1.7	-1.5	-1.2	1.2	-1.5	-0.9	-1.2	1.2	0.1	-1.5	1.5	-1.8
Reaction time premature initiations	1.2	1.6	3.7	1.2	-1.4	1.6	1.2	-1.2	-1.0	1.0	-1.2	1.4	-1.3	-0.5	1.0	-1.3	-1.5	-0.5	1.4	-1.5	-1.6	-1.4	1.9	-1.0	-1.4	1.5	-0.7
Intermittent access day 1 locomotion	1.2	1.2	2.7	1.0	-0.5	-1.0	0.6	-0.6	-1.3	1.3	-1.3	0.5	-0.5	-1.3	1.5	-1.1	-0.9	-1.2	0.5	-0.9	-1.6	-1.5	1.7	-1.3	-1.0	0.8	-0.3
Post-drug Anxiety	1.2	1.4	2.7	-1.4	1.4	0.4	-1.2	1.2	-0.8	0.8	1.3	-1.4	1.5	-0.6	0.4	1.4	1.4	1.1	-1.4	1.4	0.7	0.9	-0.8	-0.8	1.5	-1.4	1.6
Locomotion velocity, session 2	1.2	1.4	4.1	-0.8	0.9	-1.1	-1.0	1.0	-2.0	2.0	0.5	-0.9	1.0	-1.9	1.8	0.7	0.9	0.3	-0.9	0.9	-0.6	-0.2	0.6	-2.0	0.9	-0.9	1.8
Condit. Reinf. active-inactive response ratio	1.2	1.3	2.3	-1.0	1.5	1.0	-1.3	1.3	-0.1	0.1	1.3	-1.5	1.5	-0.2	-0.4	1.3	1.3	1.0	-1.5	1.2	1.2	1.2	-1.3	-0.1	1.2	-1.2	1.1
Distance traveled after self-admin	1.2	1.3	4.4	-0.2	0.6	2.1	-0.4	0.4	-2.0	2.0	-0.6	-0.6	0.5	-1.9	1.8	-0.4	0.6	-1.1	-0.6	0.6	-1.1	-1.1	0.8	-2.0	0.7	-0.6	0.5
Total resting periods, locomotor time 1	1.2	1.3	2.6	1.1	-1.6	0.0	1.6	-1.6	0.2	-0.2	-0.8	1.6	-1.4	0.2	-0.2	-1.2	-1.6	-0.1	1.6	-1.6	-0.8	-0.8	1.4	0.2	-1.4	1.4	-1.3
Time >=10cm from walls, locomotor time 2	1.2	1.2	2.4	-1.3	1.0	-1.2	-0.8	0.8	0.5	-0.5	1.6	-1.0	1.2	0.1	-0.5	1.5	1.3	1.4	-1.0	1.3	1.2	1.3	-1.4	0.5	1.2	-1.2	1.2
Zn content in liver	1.2	1.3	5.1	-0.4	0.5	-1.4	-0.5	0.5	-1.6	1.6	-0.9	-0.5	0.2	-1.7	2.0	-0.8	0.5	-2.3	-0.5	0.5	-1.4	-1.6	0.6	-1.6	0.5	-0.5	-0.0
Left kidney weight	1.1	3.1	7.8	1.2	-1.5	-2.1	1.2	-1.2	-2.5	2.5	-1.5	1.5	-1.1	-2.1	2.3	-1.2	-1.2	-0.9	1.5	-1.3	-2.4	-1.8	2.8	-2.5	-1.3	1.3	0.4
Reaction time mean	1.1	1.5	6.0	1.1	-1.0	-1.0	1.0	-1.0	0.0	-0.0	-1.8	1.0	-1.3	-0.2	0.4	-2.0	-1.0	-2.4	1.0	-0.9	-1.2	-1.8	0.9	0.0	-1.0	0.9	-2.0
Reaction time mean AUC	1.1	1.5	7.3	1.0	-0.9	-1.1	0.9	-0.9	-0.1	0.1	-1.9	0.9	-1.3	-0.4	0.6	-2.1	-0.9	-2.7	0.9	-0.9	-1.3	-1.9	0.9	-0.1	-0.9	0.9	-2.0
Median of all reaction times	1.1	1.4	7.6	0.7	-0.8	-1.6	0.8	-0.8	-0.2	0.2	-1.8	0.8	-1.2	-0.6	0.8	-1.9	-0.7	-2.8	0.8	-0.7	-1.4	-1.9	0.9	-0.2	-0.7	0.7	-1.8
Intermittent access terminal intake (last 3 days)	1.1	1.2	2.3	1.5	-1.0	1.1	1.3	-1.3	-0.5	0.5	-1.2	1.0	-1.0	-0.2	0.4	-1.3	-1.3	-0.9	1.0	-1.3	-1.1	-1.1	1.5	-0.5	-1.3	1.2	-1.0
Progressive ratio test 2 inactive lever presses	1.1	1.3	2.9	1.7	-1.4	-0.5	1.5	-1.5	0.5	-0.5	-0.9	1.4	-1.2	0.9	-0.4	-0.6	-1.7	0.4	1.4	-1.7	-0.5	-0.2	1.2	0.5	-1.7	1.6	-0.7
Locomotion distance, session 3	1.1	1.2	2.8	-1.2	1.0	-0.5	-1.0	1.0	-1.6	1.6	0.6	-1.0	1.0	-1.7	1.5	0.5	1.1	-0.2	-1.0	1.1	-0.4	-0.3	0.0	-1.6	1.1	-1.1	1.3
Total zone transitions, hab. session 2	1.1	1.4	2.4	1.4	-1.4	-0.2	1.4	-1.4	-0.3	0.3	-1.5	1.4	-1.3	-0.3	0.8	-1.3	-1.4	-0.9	1.4	-1.4	-1.4	-1.3	1.6	-0.3	-1.4	1.4	-0.9
Bone volume	1.1	1.9	3.1	1.5	-1.6	0.2	1.6	-1.6	1.8	-1.8	-0.4	1.6	-1.5	1.7	-1.6	-0.6	-1.6	0.9	1.6	-1.6	0.3	0.3	0.3	1.8	-1.6	1.6	-1.3
Distance traveled before self-admin	1.1	1.2	3.6	-0.2	0.2	1.3	-0.2	0.2	-1.6	1.6	-1.0	-0.2	0.0	-1.8	1.9	-0.8	0.5	-1.9	-0.2	0.5	-1.4	-1.6	0.6	-1.6	0.6	-0.5	0.0
Delta time in closed arm before/after self-admin	1.1	1.1	6.5	-1.2	1.3	2.5	-1.0	1.0	-0.9	0.9	0.4	-1.3	1.2	-0.9	0.8	0.7	1.1	-0.0	-1.3	1.1	0.1	0.2	-0.4	-0.9	1.1	-1.1	1.1
Progressive ratio	1.1	1.2	2.6	-1.4	1.1	-1.5	-1.2	1.2	0.1	-0.1	1.4	-1.1	1.2	-0.3	-0.1	1.6	1.2	1.1	-1.1	1.2	1.0	1.3	-1.1	0.1	1.2	-1.1	1.6
Mg content in liver	1.1	1.1	2.7	1.1	-1.0	-0.6	1.1	-1.1	0.2	-0.2	-1.4	1.0	-1.3	0.4	0.2	-1.6	-1.0	-1.5	1.0	-1.0	-1.0	-1.3	0.9	0.2	-1.0	1.0	-1.6
Sr content in liver	1.1	1.0	3.2	-0.8	0.8	-0.3	-1.0	1.0	-1.8	1.8	0.1	-0.8	0.7	-1.6	1.5	0.2	0.8	-1.0	-0.8	0.8	-0.6	-0.6	0.0	-1.8	0.8	-0.8	0.9
Length without tail	1.0	2.2	4.4	1.7	-2.1	-1.9	1.9	-1.9	1.2	-1.2	-1.0	2.1	-1.8	1.1	-0.8	-0.8	-1.8	0.4	2.1	-1.9	-0.5	-0.2	0.8	1.2	-1.8	1.9	-1.1
Mean num. licks in bursts	1.0	1.2	3.7	0.4	-0.1	1.2	0.1	-0.1	-1.8	1.8	-1.2	0.1	-0.4	-1.3	1.7	-1.2	-0.2	-1.9	0.1	-0.2	-1.6	-1.7	1.2	-1.8	-0.2	0.2	-0.4
Locomotor testing distance	1.0	1.7	3.3	1.2	-1.2	-1.4	1.3	-1.3	-1.1	1.1	-1.5	1.2	-1.2	-0.9	1.4	-1.3	-1.2	-1.2	1.2	-1.2	-1.8	-1.6	1.8	-1.1	-1.3	1.3	-0.5
Reaction time omissions	1.0	1.3	3.8	1.4	-1.0	-0.1	1.2	-1.2	0.7	-0.7	-1.3	1.0	-1.2	1.0	-0.6	-1.5	-1.5	-1.1	1.0	-1.5	-0.5	-0.9	0.8	0.7	-1.4	1.5	-1.9
Condit. Reinf. active-inactive response ratio	1.0	1.0	2.2	1.1	-0.9	-0.9	1.1	-1.1	1.5	-1.5	-0.4	0.9	-0.9	1.4	-1.2	-0.5	-1.2	0.3	0.9	-1.2	0.3	0.2	0.1	1.5	-1.2	1.2	-1.1
Conditioned reinforcement - actives	1.0	1.0	3.8	-0.5	0.5	-0.7	-0.5	0.5	-1.9	1.9	0.2	-0.5	0.7	-1.7	1.7	0.4	0.6	0.1	-0.5	0.6	-0.8	-0.4	0.6	-1.9	0.6	-0.6	1.4
Intermittent access standard deviation	1.0	1.0	1.9	1.3	-1.2	1.2	1.4	-1.4	0.8	-0.8	-0.9	1.2	-1.1	1.0	-0.8	-0.8	-1.2	-0.1	1.2	-1.2	-0.2	-0.2	0.6	0.8	-1.2	1.2	-1.2
One hour access (0.3 mA shock)	1.0	1.2	2.4	1.5	-1.2	0.9	1.3	-1.3	0.6	-0.6	-0.9	1.2	-1.2	1.0	-0.7	-1.1	-1.4	-0.2	1.2	-1.4	-0.3	-0.4	0.8	0.6	-1.5	1.5	-1.4
Locomotion velocity, NPP test	1.0	1.5	3.1	-1.4	1.3	0.6	-1.4	1.4	-0.7	0.7	1.5	-1.3	1.5	-0.8	0.4	1.5	1.4	1.3	-1.3	1.4	0.7	0.9	-0.8	-0.7	1.5	-1.4	1.8
Bone: elastic work	1.0	1.3	2.5	1.2	-1.0	-1.2	1.1	-1.1	-0.7	0.7	-1.6	1.0	-1.0	-0.8	1.2	-1.4	-1.1	-1.4	1.0	-1.2	-1.6	-1.6	1.4	-0.7	-1.3	1.2	-0.8
Sum of active levers in priming session hrs 5-6	1.0	1.0	2.1	-0.7	1.4	0.8	-1.2	1.2	0.3	-0.3	0.9	-1.4	1.2	0.3	-1.0	0.4	1.1	0.2	-1.4	1.1	1.2	0.8	-1.2	0.3	1.0	-1.2	-0.2
Fecal boli incidents, locomotor time 1	1.0	1.1	2.1	1.4	-1.4	0.4	1.5	-1.5	0.4	-0.4	-0.6	1.4	-1.2	0.3	-0.2	-0.6	-1.4	0.6	1.4	-1.4	-0.5	-0.3	1.0	0.4	-1.4	1.4	-0.5
Vertical activity count, locomotor time 1	1.0	1.0	2.4	-0.8	1.6	1.0	-1.5	1.5	-0.5	0.5	0.2	-1.6	1.2	-0.3	0.2	0.4	1.3	-1.0	-1.6	1.3	0.5	0.2	-1.0	-0.5	1.2	-1.3	0.4
Delay discounting water rate 6 sec	0.9	1.4	4.6	1.2	-1.5	-2.2	1.3	-1.3	-0.3	0.3	-1.1	1.5	-1.3	-0.1	0.4	-1.1	-1.3	-0.4	1.5	-1.3	-1.2	-1.0	1.3	-0.3	-1.3	1.4	-0.7
Pavlov. Cond. change in total contacts	0.9	1.2	2.0	1.2	-1.2	1.1	1.1	-1.1	1.4	-1.4	-0.5	1.2	-1.1	1.3	-1.2	-0.5	-1.3	0.6	1.2	-1.3	0.1	0.2	0.3	1.4	-1.3	1.3	-1.1
Pavlov. Cond. index score	0.9	1.1	5.6	1.0	-1.0	2.4	1.0	-1.0	1.2	-1.2	-0.4	1.0	-0.9	1.3	-1.1	-0.6	-1.1	0.7	1.0	-1.1	0.2	0.1	0.3	1.2	-1.1	1.0	-1.1
Conditioned locomotion	0.9	1.1	2.8	-0.8	0.9	-1.2	-0.8	0.8	-1.5	1.5	0.5	-0.9	1.1	-1.7	1.4	0.8	0.8	0.2	-0.9	0.8	-0.4	-0.0	0.2	-1.5	0.7	-0.8	1.7
Intermittent access intake escalation 2	0.9	0.9	1.7	1.0	-1.0	1.3	1.1	-1.1	-0.7	0.7	-1.0	1.0	-1.0	-0.4	0.6	-1.2	-1.0	-0.7	1.0	-1.0	-1.1	-1.1	1.3	-0.7	-0.8	0.9	-0.8
Intermitt. access day 15 inactive lever presses	0.9	1.0	1.8	1.2	-1.2	0.9	1.3	-1.3	0.2	-0.2	-1.0	1.2	-1.2	0.8	-0.3	-1.1	-1.3	-0.2	1.2	-1.3	-0.6	-0.7	1.0	0.2	-1.2	1.3	-1.2
Short access day 10 total inactive lever presses	0.9	1.0	2.0	1.3	-1.4	1.0	1.3	-1.3	0.6	-0.6	-0.7	1.4	-1.3	0.9	-0.6	-0.7	-1.3	0.1	1.4	-1.3	-0.3	-0.2	0.6	0.6	-1.2	1.3	-0.9
Short access day 1 locomotion	0.9	0.9	2.2	1.1	-1.0	-0.2	0.9	-0.9	-0.9	0.9	-1.1	1.0	-1.0	-0.3	0.6	-1.1	-1.0	-0.9	1.0	-1.0	-1.1	-1.1	1.5	-0.9	-1.1	0.8	-0.7
Short access day 10 total locomotion	0.9	0.9	1.8	1.3	-1.0	-1.1	1.0	-1.0	-0.6	0.6	-1.2	1.0	-0.9	-0.4	0.9	-1.0	-1.1	-0.7	1.0	-1.1	-1.3	-1.1	1.3	-0.6	-1.1	1.0	-0.5
Context. condit. distance diff. score	0.9	1.1	1.8	-1.2	1.3	0.4	-1.2	1.2	-0.7	0.7	1.1	-1.3	1.3	-0.7	0.4	1.1	1.3	0.6	-1.3	1.3	0.6	0.7	-0.8	-0.7	1.3	-1.3	1.4
Stereotopy head waving duration, day 7	0.9	1.1	1.9	1.3	-1.2	0.0	1.2	-1.2	0.5	-0.5	-1.0	1.2	-1.2	0.9	-0.5	-1.2	-1.4	-0.5	1.2	-1.3	-0.5	-0.6	1.0	0.5	-1.3	1.3	-1.4
Time in familiar zone, hab. session 2	0.9	0.9	3.8	0.4	-0.6	0.5	0.4	-0.4	2.0	-2.0	0.2	0.6	-0.5	1.5	-1.6	0.1	-0.3	0.7	0.6	-0.3	1.0	0.8	-0.8	2.0	-0.3	0.3	-0.8
Bone: apparent density	0.9	1.4	4.7	0.6	-0.8	-0.1	0.7	-0.7	2.1	-2.1	0.6	0.8	-0.6	1.9	-2.2	0.4	-0.7	1.6	0.8	-0.7	1.3	1.3	-0.8	2.1	-0.6	0.7	-0.6
Bone: maximum force	0.9	1.6	3.7	1.8	-1.6	-0.2	1.8	-1.8	0.5	-0.5	-0.6	1.6	-1.2	0.5	-0.5	-0.3	-1.8	1.2	1.6	-1.9	-0.4	0.1	1.2	0.5	-1.9	1.9	-0.3
Bone: trabecular tissue density	0.9	1.3	3.8	0.7	-0.7	-1.0	0.7	-0.7	-0.9	0.9	-1.6	0.7	-0.8	-1.7	1.6	-1.3	-0.6	-1.9	0.7	-0.5	-1.7	-1.8	1.4	-0.9	-0.7	0.6	-0.6
Time in closed arm before self-admin	0.9	1.0	5.0	0.6	-0.9	-2.2	0.7	-0.7	-0.7	0.7	-1.0	0.9	-1.0	-0.4	0.8	-1.3	-0.7	-1.4	0.9	-0.7	-1.2	-1.3	1.1	-0.7	-0.7	0.7	-0.9
Ambulatory time after self-admin	0.9	1.0	3.0	-0.2	0.4	1.7	-0.4	0.4	-1.7	1.7	-0.5	-0.4	0.3	-1.6	1.5	-0.4	0.5	-1.0	-0.4	0.5	-1.0	-1.0	0.7	-1.7	0.5	-0.6	0.4
Delay disc. indifference point, 0s delay	0.9	0.9	5.1	0.9	-1.1	-2.3	1.0	-1.0	-0.1	0.1	-1.1	1.1	-1.1	-0.2	0.6	-0.9	-1.0	-0.9	1.1	-1.0	-1.1	-1.0	1.0	-0.1	-0.9	1.0	-0.6
Rest time, locomotor task time 2	0.9	1.0	1.5	0.9	-1.1	-0.9	1.0	-1.0	-0.3	0.3	-1.2	1.1	-1.1	-0.3	0.7	-1.2	-1.2	-0.9	1.1	-1.2	-1.2	-1.2	1.2	-0.3	-1.2	1.2	-0.8
Mean time between licks in bursts	0.8	1.1	2.6	-0.9	0.9	0.5	-1.0	1.0	0.9	-0.9	1.2	-0.9	0.9	0.9	-1.4	1.1	0.9	1.1	-0.9	0.9	1.6	1.5	-1.5	0.9	0.8	-0.9	0.3
Light reinforcement 1	0.8	1.5	2.8	-1.5	1.7	1.2	-1.7	1.7	-0.7	0.7	1.0	-1.7	1.5	-0.3	0.4	1.0	1.6	0.1	-1.7	1.6	0.7	0.5	-1.1	-0.7	1.4	-1.6	1.1
Pavlov. Cond. latency score	0.8	1.1	5.2	1.0	-1.0	2.3	1.0	-1.0	1.2	-1.2	-0.4	1.0	-0.9	1.2	-1.1	-0.5	-1.0	0.7	1.0	-1.0	0.2	0.2	0.2	1.2	-1.1	1.0	-1.0
Progressive ratio test 1 active lever presses	0.8	0.8	2.1	1.0	-0.5	0.7	0.7	-0.7	-1.0	1.0	-1.1	0.5	-0.5	-0.8	1.0	-1.0	-0.8	-0.9	0.5	-0.8	-1.2	-1.2	1.4	-1.0	-1.0	0.9	-0.5
Short access total infusions	0.8	0.8	2.6	1.2	-0.6	-0.5	0.8	-0.8	-1.1	1.1	-1.0	0.6	-0.5	-0.9	1.2	-0.7	-0.9	-0.5	0.6	-0.9	-1.3	-1.0	1.6	-1.1	-1.2	0.9	0.0
Total zone transitions, hab. session 1	0.8	1.2	2.4	1.3	-1.2	-0.5	1.2	-1.2	-0.7	0.7	-1.2	1.2	-1.1	-0.4	0.8	-1.1	-1.2	-0.6	1.2	-1.2	-1.4	-1.2	1.6	-0.7	-1.3	1.2	-0.6
Locomotion velocity, hab. session 1	0.8	1.1	2.5	-1.0	1.2	0.5	-1.1	1.1	-0.4	0.4	1.4	-1.2	1.4	0.2	-0.4	1.5	1.0	1.6	-1.2	1.0	1.1	1.3	-0.9	-0.4	1.0	-1.0	1.4
Bone: cortical thickness	0.8	1.0	1.9	1.0	-1.2	-1.4	1.2	-1.2	-0.2	0.2	-0.9	1.2	-1.1	-0.1	0.4	-0.7	-1.3	-0.0	1.2	-1.4	-1.0	-0.7	1.3	-0.2	-1.3	1.4	-0.4
Bone: endosteal estimation	0.8	1.7	3.0	1.6	-1.6	0.1	1.7	-1.7	1.3	-1.3	-0.7	1.6	-1.5	1.1	-1.0	-0.9	-1.7	0.2	1.6	-1.6	-0.3	-0.2	0.7	1.3	-1.7	1.6	-1.4
Bone: marrow area	0.8	1.7	3.1	1.6	-1.6	0.2	1.7	-1.7	1.3	-1.3	-0.8	1.6	-1.5	1.1	-1.0	-0.9	-1.7	0.2	1.6	-1.6	-0.3	-0.2	0.7	1.3	-1.7	1.6	-1.4
Bone: maximum moment	0.8	1.4	3.3	1.7	-1.5	-0.0	1.7	-1.7	0.6	-0.6	-0.6	1.5	-1.2	0.6	-0.6	-0.3	-1.7	1.2	1.5	-1.8	-0.3	0.1	1.0	0.6	-1.8	1.8	-0.3
Bone: trabecular number	0.8	1.2	4.3	0.2	-0.4	-0.1	0.4	-0.4	1.9	-1.9	0.7	0.4	-0.3	1.8	-2.1	0.6	-0.3	1.5	0.4	-0.4	1.4	1.4	-1.0	1.9	-0.3	0.4	-0.4
Total heroin consumption	0.8	1.0	1.9	0.9	-1.1	1.2	1.2	-1.2	1.1	-1.1	-0.5	1.1	-1.1	1.2	-1.3	-0.7	-1.0	0.3	1.1	-1.0	0.3	0.1	0.2	1.1	-0.9	0.9	-1.4
Delay disc. indifference point, 2s delay	0.8	0.9	4.6	0.7	-0.4	-0.8	0.6	-0.6	-0.7	0.7	-1.6	0.4	-0.6	-0.7	1.0	-1.3	-0.4	-2.2	0.4	-0.4	-1.2	-1.5	0.8	-0.7	-0.9	0.5	-1.0
Locomotion in novel chamber	0.8	1.0	1.8	-1.2	1.1	0.2	-1.1	1.1	-1.3	1.3	0.2	-1.1	1.0	-1.3	1.2	0.3	1.2	-0.7	-1.1	1.3	-0.3	-0.3	-0.1	-1.3	1.3	-1.2	0.8
Extensor digitorum longus weight	0.7	2.7	6.4	1.9	-1.7	0.2	1.8	-1.8	1.9	-1.9	-1.6	1.7	-1.8	2.1	-1.5	-1.6	-1.8	-1.0	1.7	-1.8	-0.2	-0.5	0.4	1.9	-1.9	1.8	-2.5
Tibialis anterior weight	0.7	2.3	7.1	1.6	-1.5	-0.2	1.5	-1.5	1.4	-1.4	-1.9	1.5	-1.8	1.5	-0.9	-2.0	-1.5	-1.9	1.5	-1.5	-0.6	-1.2	0.6	1.4	-1.5	1.5	-2.7
Number of licking bursts	0.7	0.8	3.2	-0.5	0.1	-0.9	-0.1	0.1	1.2	-1.2	1.1	-0.1	0.3	1.1	-1.3	1.1	0.2	1.8	-0.1	0.2	1.3	1.5	-0.8	1.2	0.2	-0.2	0.6
Delay discounting water rate 24 sec	0.7	0.9	1.5	0.8	-1.2	-1.2	1.0	-1.0	-0.2	0.2	-1.1	1.2	-1.2	-0.3	0.6	-1.2	-1.0	-0.9	1.2	-1.0	-1.2	-1.2	1.1	-0.2	-0.9	1.0	-0.8
Condit. Reinf. lever presses	0.7	0.9	1.7	0.9	-1.0	1.3	0.9	-0.9	1.3	-1.3	-0.2	1.0	-0.8	1.2	-1.2	-0.3	-1.0	0.8	1.0	-1.0	0.3	0.3	0.1	1.3	-1.0	1.0	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	5.0	1.0	-1.0	2.2	1.0	-1.0	0.9	-0.9	-0.5	1.0	-0.9	1.1	-0.9	-0.6	-1.0	0.5	1.0	-1.0	0.0	-0.0	0.4	0.9	-1.1	1.0	-1.0
Pavlov. Cond. response bias	0.7	0.9	6.1	0.8	-0.8	2.5	0.8	-0.8	1.0	-1.0	-0.0	0.8	-0.6	1.4	-1.3	-0.2	-0.9	1.1	0.8	-0.9	0.5	0.5	0.1	1.0	-1.0	0.8	-0.8
Compulsive drug intake	0.7	0.7	1.3	-0.6	1.0	-0.2	-0.9	0.9	0.6	-0.6	0.9	-1.0	1.0	0.9	-0.9	0.8	0.7	0.9	-1.0	0.7	1.1	1.0	-1.0	0.6	0.5	-0.5	0.3
Degree of sensitization distance	0.7	0.7	1.5	1.0	-0.8	-0.6	0.9	-0.9	1.2	-1.2	-0.3	0.8	-0.8	1.0	-1.0	-0.2	-0.9	0.4	0.8	-0.9	0.3	0.3	-0.0	1.2	-1.0	0.9	-0.7
Condit. Reinf. inactive responses	0.7	0.8	3.0	-0.7	0.4	1.1	-0.6	0.6	0.8	-0.8	1.2	-0.4	0.6	0.8	-1.0	1.2	0.6	1.7	-0.4	0.5	1.2	1.4	-1.0	0.8	0.5	-0.5	0.8
Time in novel zone, hab. session 1	0.7	0.7	2.4	0.9	-0.6	0.2	0.7	-0.7	1.1	-1.1	0.2	0.6	-0.3	1.4	-1.2	0.4	-0.9	1.5	0.6	-0.9	0.7	0.9	-0.1	1.1	-0.9	0.9	-0.1
Time in novel zone, hab. session 2	0.7	0.7	3.0	-0.2	0.4	-1.1	-0.2	0.2	-1.7	1.7	-0.4	-0.4	0.3	-1.2	1.4	-0.2	0.1	-0.7	-0.4	0.1	-0.9	-0.8	0.8	-1.7	0.1	-0.1	0.6
Novel to familiar place preference ratio	0.7	0.8	2.5	-0.3	0.6	1.0	-0.5	0.5	0.8	-0.8	1.1	-0.6	0.7	0.9	-1.2	1.2	0.3	1.6	-0.6	0.3	1.4	1.5	-1.0	0.8	0.3	-0.3	0.7
Time in novel zone, NPP test	0.7	0.7	2.3	0.1	0.2	0.8	-0.0	0.0	1.1	-1.1	0.8	-0.2	0.3	1.2	-1.5	0.9	-0.1	1.5	-0.2	-0.1	1.3	1.4	-0.9	1.1	-0.1	0.1	0.2
Bone: cortical porosity	0.7	0.7	2.4	-0.4	0.5	1.3	-0.4	0.4	1.2	-1.2	0.6	-0.5	0.4	1.5	-1.5	0.4	0.4	0.6	-0.5	0.3	1.3	1.0	-1.3	1.2	0.4	-0.4	-0.5
Bone: stiffness	0.7	1.1	2.5	1.4	-1.4	0.3	1.5	-1.5	0.3	-0.3	-0.2	1.4	-0.9	0.6	-0.4	-0.1	-1.5	1.6	1.4	-1.6	-0.3	0.3	1.0	0.3	-1.5	1.5	0.0
Breakpoint value in progressive ratio session	0.7	0.8	3.6	0.8	-0.4	1.9	0.5	-0.5	1.3	-1.3	-0.5	0.4	-0.6	1.4	-1.6	-0.5	-0.4	-0.0	0.4	-0.4	0.7	0.3	-0.5	1.3	-0.6	0.4	-1.4
Rest time, locomotor task time 1	0.7	0.8	2.0	0.1	-1.0	-1.0	0.9	-0.9	-1.1	1.1	-0.2	1.0	-0.6	-1.1	1.2	-0.2	-0.7	0.6	1.0	-0.7	-1.2	-0.6	1.4	-1.1	-0.6	0.7	0.7
Run reversals in cocaine runway, males	0.7	0.6	1.4	-1.1	0.7	0.1	-0.8	0.8	-1.2	1.2	0.2	-0.7	0.6	-1.0	1.1	0.0	0.9	-0.7	-0.7	0.9	-0.5	-0.6	0.2	-1.2	1.1	-0.9	0.5
Locomotor activity	0.6	0.9	2.0	1.1	-1.1	-1.4	1.1	-1.1	-0.2	0.2	-1.0	1.1	-1.1	0.3	0.3	-0.9	-1.1	-0.6	1.1	-1.2	-0.9	-0.8	1.1	-0.2	-1.2	1.2	-0.6
Social response proportion	0.6	0.6	1.5	0.4	-0.6	0.1	0.5	-0.5	-1.0	1.0	-0.9	0.6	-0.6	-1.1	1.2	-0.8	-0.6	-1.0	0.6	-0.6	-1.2	-1.2	1.2	-1.0	-0.3	0.5	-0.2
Pavlov. Cond. lever latency	0.6	0.9	4.3	-0.5	0.5	-2.1	-0.5	0.5	-1.3	1.3	-0.4	-0.5	0.3	-1.4	1.6	-0.2	0.6	-1.5	-0.5	0.6	-0.9	-0.9	0.3	-1.3	0.6	-0.5	0.5
Short access day 10 total infusions	0.6	0.7	1.9	0.4	0.0	-1.0	0.1	-0.1	-1.4	1.4	-0.8	-0.0	0.0	-1.3	1.3	-0.5	-0.2	-0.8	-0.0	-0.2	-1.1	-0.9	1.1	-1.4	-0.5	0.2	0.3
Locomotion velocity, session 7	0.6	0.6	1.2	1.0	-1.1	-1.0	1.1	-1.1	0.2	-0.2	-0.3	1.1	-0.9	-0.5	0.3	-0.2	-1.0	0.5	1.1	-1.0	-0.6	-0.2	0.9	0.2	-1.1	1.0	0.1
Total locomotion distance, hab. session 1	0.6	0.9	2.9	-0.8	1.0	0.3	-0.9	0.9	-0.1	0.1	1.4	-1.0	1.2	0.3	-0.6	1.4	0.8	1.7	-1.0	0.8	1.2	1.4	-0.9	-0.1	0.8	-0.8	1.2
Total locomotion distance, NPP test	0.6	0.9	2.0	-1.1	0.9	0.4	-1.0	1.0	-0.2	0.2	1.3	-0.9	1.1	-0.3	-0.1	1.3	1.1	1.4	-0.9	1.1	0.8	1.1	-0.8	-0.2	1.1	-1.1	1.3
Pavlov. Cond. intertrial magazine entries	0.6	0.8	1.6	-1.1	0.9	0.3	-1.1	1.1	-0.3	0.3	0.9	-0.9	1.0	-0.3	0.0	1.2	1.1	0.8	-0.9	1.0	0.7	0.9	-0.8	-0.3	1.1	-1.0	1.3
Bone: connectivity density	0.6	0.9	2.7	-0.6	0.3	0.8	-0.3	0.3	1.1	-1.1	1.2	-0.3	0.4	1.2	-1.6	1.0	0.4	1.7	-0.3	0.4	1.5	1.5	-1.3	1.1	0.5	-0.4	0.3
Time in closed arm after self-admin	0.6	0.7	2.0	-0.7	0.3	0.8	-0.3	0.3	-1.3	1.3	-0.5	-0.3	0.1	-1.2	1.4	-0.4	0.6	-1.3	-0.3	0.6	-0.9	-1.0	0.4	-1.3	0.6	-0.5	0.2
Seeking ratio, punishment vs. effort	0.6	0.8	5.0	0.8	-0.6	2.2	0.6	-0.6	-0.3	0.3	-1.1	0.6	-0.7	-0.1	0.5	-1.2	-0.7	-1.1	0.6	-0.8	-0.9	-1.2	0.7	-0.3	-0.7	0.6	-1.0
Latency to leave start box in cocaine runway	0.6	0.6	1.9	1.1	-0.5	-0.1	0.6	-0.6	0.5	-0.5	-0.9	0.5	-0.7	0.3	-0.3	-1.1	-1.1	-0.9	0.5	-1.1	-0.4	-0.7	0.6	0.5	-1.0	1.2	-1.4
Length with tail	0.5	1.7	3.4	1.6	-1.8	-1.4	1.5	-1.5	1.1	-1.1	-1.0	1.8	-1.7	1.1	-0.9	-1.2	-1.3	-0.3	1.8	-1.4	-0.4	-0.4	0.6	1.1	-1.6	1.5	-1.6
Tibia length	0.5	1.3	2.8	1.4	-1.5	1.1	1.5	-1.5	-0.3	0.3	-0.9	1.5	-1.2	-0.2	0.5	-0.7	-1.5	0.4	1.5	-1.4	-1.1	-0.7	1.7	-0.3	-1.5	1.5	-0.2
Indifference point function ln k	0.5	0.8	1.6	-1.2	1.0	-1.3	-1.0	1.0	-0.5	0.5	0.9	-1.0	1.0	-0.6	0.6	0.8	1.1	0.3	-1.0	1.1	0.3	0.3	-0.7	-0.5	1.1	-1.0	1.0
Indifference point function log k	0.5	0.8	1.6	-1.2	1.0	-1.3	-1.0	1.0	-0.5	0.5	0.9	-1.0	1.0	-0.6	0.6	0.8	1.1	0.3	-1.0	1.1	0.3	0.3	-0.7	-0.5	1.1	-1.0	1.0
Delay discounting water rate 0 sec	0.5	0.7	1.5	1.1	-1.2	-1.2	1.0	-1.0	0.5	-0.5	-0.5	1.2	-0.9	0.7	-0.4	-0.4	-1.1	0.4	1.2	-1.1	-0.3	-0.1	0.7	0.5	-1.1	1.1	-0.5
Reaction time premature initiation rate	0.5	0.6	4.4	-0.1	-0.2	2.1	0.0	-0.0	-1.4	1.4	0.0	0.2	-0.1	-0.9	1.1	-0.2	-0.2	0.2	0.2	-0.2	-0.9	-0.6	1.0	-1.4	-0.0	0.2	0.5
Cocaine response before conditioning	0.5	0.7	2.0	-0.3	0.2	0.4	-0.4	0.4	1.2	-1.2	0.8	-0.2	0.3	1.3	-1.4	0.6	0.4	1.0	-0.2	0.4	1.2	1.1	-1.1	1.2	0.4	-0.4	-0.1
Condit. Reinf. inactive responses	0.5	0.6	1.8	0.7	-0.8	0.1	0.6	-0.6	1.3	-1.3	-0.1	0.8	-0.8	1.3	-1.2	-0.3	-0.6	0.4	0.8	-0.6	0.4	0.3	-0.1	1.3	-0.7	0.6	-0.9
Pavlov. Cond. magazine entry latency	0.5	0.6	3.4	0.6	-0.7	1.8	0.6	-0.6	0.9	-0.9	-0.5	0.7	-0.7	1.0	-0.8	-0.7	-0.7	0.0	0.7	-0.7	0.0	-0.2	0.1	0.9	-0.6	0.6	-1.1
Pavlov. Cond. lever contacts	0.5	0.7	5.2	0.8	-0.7	2.3	0.7	-0.7	0.8	-0.8	-0.1	0.7	-0.5	1.1	-1.0	-0.2	-0.8	1.0	0.7	-0.8	0.3	0.4	0.2	0.8	-0.9	0.7	-0.6
Pavlov. Cond. magazine entry number	0.5	0.6	3.0	-0.7	0.8	-1.7	-0.7	0.7	-0.9	0.9	0.5	-0.8	0.8	-0.9	0.7	0.6	0.8	-0.1	-0.8	0.8	0.0	0.2	-0.1	-0.9	0.7	-0.7	1.0
Short access day 1 total infusions	0.5	0.5	1.5	0.6	-0.2	-0.1	0.3	-0.3	-1.2	1.2	-0.8	0.2	-0.2	-0.7	1.0	-0.5	-0.3	-0.7	0.2	-0.3	-1.0	-0.9	1.2	-1.2	-0.5	0.3	0.1
Locomotion distance, session 1	0.5	0.6	2.2	-0.5	0.4	-1.1	-0.4	0.4	-1.4	1.4	0.2	-0.4	0.5	-1.5	1.4	0.3	0.5	0.1	-0.4	0.5	-0.6	-0.4	0.5	-1.4	0.5	-0.5	1.1
Locomotion velocity, session 3	0.5	0.6	1.9	-0.6	0.7	0.5	-0.6	0.6	-1.4	1.4	0.3	-0.7	0.8	-1.1	1.1	0.4	0.5	0.2	-0.7	0.5	-0.4	-0.2	0.3	-1.4	0.5	-0.5	1.0
Novelty place preference	0.5	0.5	1.8	-0.2	0.5	0.9	-0.3	0.3	0.7	-0.7	0.9	-0.5	0.6	0.8	-1.1	1.0	0.2	1.3	-0.5	0.2	1.1	1.3	-0.8	0.7	0.2	-0.2	0.5
Bone surface	0.5	0.8	2.5	0.5	-0.7	0.8	0.7	-0.7	1.3	-1.3	0.5	0.7	-0.5	1.4	-1.5	0.4	-0.6	1.6	0.7	-0.7	0.9	1.1	-0.4	1.3	-0.6	0.7	-0.2
Bone: cortical porosity	0.5	0.6	1.4	-0.6	0.6	1.0	-0.5	0.5	0.8	-0.8	0.7	-0.6	0.6	1.2	-1.2	0.5	0.6	0.6	-0.6	0.5	1.2	0.9	-1.2	0.8	0.6	-0.5	-0.1
Bone: elastic displacement	0.5	0.5	1.5	0.7	-0.7	-1.2	0.6	-0.6	0.1	-0.1	-1.1	0.7	-0.8	-0.1	0.4	-1.0	-0.6	-1.2	0.7	-0.7	-0.8	-1.0	0.6	0.1	-0.7	0.6	-0.9
Ambulatory time before self-admin	0.5	0.5	1.8	0.0	-0.2	0.2	0.1	-0.1	-1.1	1.1	-0.8	0.2	-0.2	-1.2	1.3	-0.6	0.2	-1.2	0.2	0.2	-1.1	-1.1	0.6	-1.1	0.2	-0.2	0.0
Food seeking constrained by brief footshock	0.5	0.6	1.8	-1.0	0.8	1.4	-0.9	0.9	0.3	-0.3	0.9	-0.8	0.8	-0.0	-0.2	0.9	0.8	0.5	-0.8	0.8	0.7	0.7	-1.2	0.3	0.8	-0.9	0.7
Run reversals in cocaine runway, females	0.5	0.5	3.6	1.1	-0.8	-1.9	0.8	-0.8	0.4	-0.4	-0.4	0.8	-0.6	0.1	-0.4	-0.3	-0.7	0.1	0.8	-0.7	-0.1	-0.0	0.4	0.4	-0.9	0.6	-0.4
Co content in liver	0.5	0.6	2.3	-0.4	0.4	0.8	-0.4	0.4	-0.9	0.9	0.8	-0.4	0.6	-1.3	0.9	0.9	0.5	1.3	-0.4	0.5	-0.2	0.3	0.2	-0.9	0.4	-0.5	1.5
Fe content in liver	0.5	0.6	1.9	-0.6	0.7	-0.0	-0.6	0.6	0.3	-0.3	1.1	-0.7	0.9	1.2	-0.9	1.1	0.6	1.4	-0.7	0.6	1.1	1.3	-0.9	0.3	0.5	-0.6	0.7
Delay discounting water rate 18 sec	0.4	0.6	2.2	0.8	-0.8	-1.5	0.7	-0.7	-0.2	0.2	-0.9	0.8	-0.7	-0.5	0.6	-0.5	-0.9	-0.4	0.8	-1.0	-0.8	-0.6	0.9	-0.2	-1.0	1.0	-0.1
Saline control response	0.4	0.5	1.1	0.5	-0.5	-1.1	0.6	-0.6	-0.7	0.7	-1.0	0.5	-0.5	-0.6	0.8	-0.8	-0.5	-0.9	0.5	-0.5	-0.9	-0.9	1.0	-0.7	-0.5	0.4	-0.3
Progressive ratio test 1 breakpoint	0.4	0.5	1.1	1.0	-0.3	0.7	0.6	-0.6	-0.6	0.6	-0.9	0.3	-0.3	-0.6	0.6	-0.8	-0.6	-0.7	0.3	-0.6	-0.9	-0.9	1.0	-0.6	-0.8	0.7	-0.4
Number of responses in last shaping day	0.4	0.4	1.0	0.5	-0.7	-0.7	0.5	-0.5	-1.0	1.0	-0.6	0.7	-0.5	-0.6	0.8	-0.4	-0.3	-0.3	0.7	-0.3	-0.8	-0.6	1.0	-1.0	-0.6	0.3	0.1
Pavlov. Cond. lever latency	0.4	0.5	0.8	0.9	-0.8	-0.4	0.7	-0.7	0.9	-0.9	-0.5	0.8	-0.8	0.7	-0.7	-0.4	-0.8	-0.2	0.8	-0.7	0.0	0.0	0.2	0.9	-0.8	0.7	-0.8
Delay disc. indifference point, 16s delay	0.4	0.4	1.6	0.6	-0.6	0.4	0.6	-0.6	0.5	-0.5	-0.9	0.6	-0.8	0.4	-0.2	-1.0	-0.4	-1.2	0.6	-0.4	-0.4	-0.7	0.1	0.5	-0.4	0.5	-1.3
Delay disc. indifference point, 24s delay	0.4	0.4	1.2	0.5	-0.7	1.1	0.5	-0.5	0.8	-0.8	-0.3	0.7	-0.8	0.7	-0.7	-0.6	-0.2	-0.3	0.7	-0.2	0.1	-0.1	-0.2	0.8	-0.2	0.2	-1.0
Na content in liver	0.4	0.4	2.0	0.7	-0.5	0.3	0.5	-0.5	0.4	-0.4	-0.9	0.5	-0.7	0.9	-0.3	-1.1	-0.6	-1.1	0.5	-0.6	-0.3	-0.7	0.2	0.4	-0.6	0.6	-1.4
Delay discounting time to switch 0 sec	0.3	0.5	1.0	-1.0	0.9	0.6	-0.8	0.8	-0.3	0.3	0.3	-0.9	0.6	-0.5	0.3	0.1	0.9	-0.7	-0.9	0.9	0.2	-0.2	-0.7	-0.3	1.0	-0.9	0.1
Reaction time num false alarms	0.3	0.4	1.1	-0.4	0.7	0.6	-0.6	0.6	-0.4	0.4	0.6	-0.7	0.8	-1.1	0.4	0.7	0.5	0.6	-0.7	0.5	0.2	0.4	-0.3	-0.4	0.5	-0.4	1.0
Intermitt. access escalation Index	0.3	0.3	1.9	-0.1	0.7	1.4	-0.5	0.5	-0.6	0.6	-0.1	-0.7	0.5	-0.5	0.5	-0.2	0.5	-0.7	-0.7	0.5	-0.2	-0.4	0.1	-0.6	0.2	-0.3	-0.0
Short access day 1 total inactive lever presses	0.3	0.4	0.8	-0.3	0.8	0.1	-0.7	0.7	-0.2	0.2	0.6	-0.8	0.9	0.3	-0.3	0.9	0.5	0.7	-0.8	0.5	0.7	0.9	-0.3	-0.2	0.5	-0.5	0.8
Locomotion distance, session 2	0.3	0.5	1.6	-0.0	-0.0	-0.8	0.1	-0.1	-1.2	1.2	-0.0	0.0	0.1	-1.2	1.3	0.1	0.0	0.2	0.0	-0.0	-0.8	-0.4	0.8	-1.2	-0.0	0.0	0.9
Time in familiar zone, hab. session 1	0.3	0.3	2.0	-0.2	-0.0	0.0	-0.1	0.1	-0.5	0.5	-0.5	0.0	-0.3	-0.8	0.6	-0.8	0.3	-1.4	0.0	0.3	-0.6	-0.9	0.3	-0.5	0.2	-0.3	-0.6
Pavlov. Cond. magazine entry latency	0.3	0.4	0.8	-0.8	0.9	0.7	-0.8	0.8	-0.3	0.3	0.6	-0.9	0.8	0.1	0.1	0.5	0.8	0.2	-0.9	0.8	0.4	0.3	-0.6	-0.3	0.8	-0.8	0.4
Pavlov. Cond. response bias	0.3	0.3	0.7	-0.7	0.8	0.7	-0.7	0.7	-0.5	0.5	0.3	-0.8	0.7	-0.3	0.4	0.2	0.7	-0.2	-0.8	0.7	0.1	-0.1	-0.3	-0.5	0.7	-0.7	0.3
Extinction: sum of active levers before priming	0.3	0.3	1.0	-0.5	0.6	-1.0	-0.5	0.5	0.5	-0.5	0.2	-0.6	0.4	0.8	-0.9	0.0	0.4	-0.3	-0.6	0.4	0.8	0.4	-0.7	0.5	0.3	-0.4	-0.5
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	1.2	0.5	-0.0	1.1	0.4	-0.4	-0.2	0.2	-0.8	0.0	-0.3	0.0	0.1	-0.8	-0.3	-1.0	0.0	-0.3	-0.4	-0.7	0.4	-0.2	-0.4	0.2	-0.9
Delay disc. indifference point, 4s delay	0.3	0.3	2.3	0.5	-0.4	0.0	0.5	-0.5	0.1	-0.1	-1.0	0.4	-0.6	-0.1	0.1	-1.0	-0.2	-1.5	0.4	-0.2	-0.5	-0.8	0.2	0.1	-0.3	0.2	-1.1
Total resting periods, locomotor time 2	0.3	0.3	1.8	0.2	-0.5	-0.5	0.4	-0.4	-0.3	0.3	-0.6	0.5	-0.7	-0.3	0.5	-1.0	-0.1	-1.3	0.5	-0.1	-0.7	-1.0	0.2	-0.3	-0.2	-0.0	-0.9
Vertical activity count, locomotor time 2	0.3	0.3	0.9	-0.7	0.5	0.2	-0.2	0.2	-0.0	0.0	0.9	-0.5	0.6	0.2	-0.2	0.9	0.5	0.9	-0.5	0.5	0.6	0.8	-0.6	-0.0	0.9	-0.7	0.8
Water consumed over 24 hours	0.2	0.3	1.0	-0.4	0.1	0.3	-0.3	0.3	-1.0	1.0	-0.2	-0.1	0.2	-0.9	1.0	0.0	0.4	-0.3	-0.1	0.4	-0.5	-0.4	0.3	-1.0	0.4	-0.4	0.5
Reaction time num false alarms AUC	0.2	0.3	1.8	-0.2	0.6	0.7	-0.4	0.4	-0.7	0.7	0.2	-0.6	0.6	-1.4	0.8	0.4	0.4	0.1	-0.6	0.4	-0.2	-0.1	0.0	-0.7	0.3	-0.3	0.8
Conditioned locomotion	0.2	0.2	0.6	0.3	-0.3	-0.5	0.4	-0.4	-0.4	0.4	-0.7	0.3	-0.4	0.4	0.4	-0.7	-0.4	-0.8	0.3	-0.4	-0.6	-0.7	0.6	-0.4	-0.5	0.4	-0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.2	1.1	0.6	-0.5	-1.1	0.5	-0.5	0.3	-0.3	-0.1	0.5	-0.5	0.4	-0.4	-0.2	-0.5	0.2	0.5	-0.5	-0.0	0.1	0.4	0.3	-0.6	0.6	-0.3
Conditioned reinforcement - inactives	0.2	0.2	0.9	0.9	-0.3	1.0	0.5	-0.5	-0.3	0.3	-0.4	0.3	-0.2	0.3	-0.2	-0.2	-0.6	0.4	0.3	-0.6	-0.2	-0.0	0.6	-0.3	-0.9	0.8	-0.2
Intermittent access day 1 total infusions	0.2	0.2	0.7	0.7	-0.3	0.1	0.5	-0.5	-0.4	0.4	-0.5	0.3	-0.3	-0.4	0.4	-0.4	-0.6	-0.1	0.3	-0.6	-0.6	-0.5	0.8	-0.4	-0.8	0.6	-0.2
Progressive ratio test 1 inactive lever presses	0.2	0.2	1.7	0.3	0.3	1.3	-0.2	0.2	-0.6	0.6	-0.2	-0.3	0.3	0.2	-0.0	0.0	-0.1	0.0	-0.3	-0.1	0.0	0.0	0.5	-0.6	-0.4	0.2	0.1
Locomotion velocity, session 1	0.2	0.3	0.5	-0.6	0.6	-0.1	-0.5	0.5	-0.6	0.6	0.4	-0.6	0.6	-0.7	0.3	0.4	0.6	0.3	-0.6	0.6	0.1	0.1	-0.1	-0.6	0.6	-0.6	0.6
Degree of sensitization stereotypy	0.2	0.2	0.7	0.5	-0.5	0.0	0.6	-0.6	0.0	-0.0	-0.1	0.5	-0.4	0.8	-0.4	-0.4	-0.7	0.3	0.5	-0.7	-0.1	-0.0	0.5	0.0	-0.6	0.7	-0.5
Total zone transitions, NPP test	0.2	0.3	0.8	0.5	-0.7	-0.2	0.5	-0.5	-0.5	0.5	-0.4	0.7	-0.6	-0.3	0.6	-0.5	-0.5	-0.2	0.7	-0.5	-0.8	-0.6	0.9	-0.5	-0.4	0.5	-0.2
Pavlov. Cond. change in total contacts	0.2	0.2	0.4	-0.6	0.7	0.6	-0.6	0.6	-0.3	0.3	0.2	-0.7	0.5	-0.3	0.1	-0.0	0.6	-0.2	-0.7	0.6	0.1	-0.1	-0.3	-0.3	0.6	-0.6	-0.0
Active lever presses in extinction session 6	0.2	0.2	0.5	-0.4	0.4	-0.3	-0.3	0.3	0.1	-0.1	-0.1	-0.4	0.3	0.3	-0.6	-0.1	0.6	-0.7	-0.4	0.6	0.5	0.2	-0.5	0.1	0.5	-0.6	-0.4
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.5	0.7	-0.3	0.7	0.6	-0.6	-0.3	0.3	-0.6	0.3	-0.2	-0.1	0.2	-0.2	-0.6	0.0	0.3	-0.5	-0.4	-0.3	0.6	-0.3	-0.6	0.4	-0.1
Bouts of movement, locomotor time 2	0.2	0.2	1.1	-0.3	0.1	-0.4	-0.1	0.1	-0.4	0.4	-0.1	-0.1	-0.1	-0.3	0.4	-0.6	0.4	-1.0	-0.1	0.4	-0.3	-0.7	-0.2	-0.4	0.3	-0.5	-0.5
Cu content in liver	0.2	0.2	0.6	0.3	-0.4	0.2	0.4	-0.4	-0.6	0.6	-0.5	0.4	-0.3	-0.5	0.6	-0.4	-0.3	-0.3	0.4	-0.3	-0.7	-0.6	0.8	-0.6	-0.3	0.3	-0.0
K content in liver	0.2	0.2	0.4	0.3	-0.3	0.4	0.4	-0.4	-0.3	0.3	-0.5	0.3	-0.4	0.1	0.2	-0.7	-0.2	-0.6	0.3	-0.2	-0.5	-0.6	0.4	-0.3	-0.3	0.2	-0.6
Mn content in liver	0.2	0.2	0.6	-0.4	0.5	0.2	-0.5	0.5	-0.7	0.7	-0.0	-0.5	0.3	-0.1	0.4	-0.2	0.4	-0.8	-0.5	0.4	-0.2	-0.4	-0.1	-0.7	0.4	-0.4	-0.1
Se content in liver	0.2	0.2	1.3	-0.1	0.2	0.5	-0.1	0.1	0.3	-0.3	0.7	-0.2	0.4	0.7	-0.6	0.7	0.2	1.1	-0.2	0.2	0.6	0.8	-0.3	0.3	0.1	-0.2	0.5
Tail length	0.1	0.2	0.9	0.4	-0.4	0.0	0.2	-0.2	0.7	-0.7	-0.2	0.4	-0.5	1.0	-0.9	-0.4	-0.1	-0.3	0.4	-0.0	0.3	0.1	-0.3	0.7	-0.3	0.1	-0.9
Times rat made contact with spout	0.1	0.1	0.4	-0.3	0.0	0.5	-0.1	0.1	-0.7	0.7	-0.0	-0.0	0.1	0.1	0.3	0.0	0.0	0.1	-0.0	0.0	-0.2	-0.1	0.3	-0.7	0.1	-0.0	0.2
Stereotopy head waving bouts, day 3	0.1	0.1	1.4	0.0	0.0	1.2	-0.1	0.1	0.3	-0.3	-0.3	-0.0	-0.1	-0.2	0.1	-0.2	0.1	-0.5	-0.0	0.1	-0.1	-0.3	-0.2	0.3	0.1	-0.1	-0.3
Stereotopy head waving duration, day 3	0.1	0.1	0.4	0.2	-0.1	0.5	0.0	-0.0	0.6	-0.6	-0.2	0.1	-0.1	0.1	-0.3	0.0	-0.1	0.0	0.1	-0.1	0.2	0.1	-0.3	0.6	-0.1	0.1	-0.2
Locomotion distance, session 7	0.1	0.2	1.3	0.2	-0.3	-1.1	0.4	-0.4	-0.4	0.4	-0.0	0.3	-0.2	-0.8	0.7	0.1	-0.2	0.1	0.3	-0.2	-0.5	-0.2	0.4	-0.4	-0.3	0.2	0.5
Stereotopy head waving bouts, day 7	0.1	0.1	0.5	0.1	0.0	0.7	0.1	-0.1	-0.0	0.0	0.3	-0.0	0.1	0.5	-0.4	0.1	-0.2	0.6	-0.0	-0.2	0.2	0.3	0.1	-0.0	-0.1	0.2	-0.0
Pavlov. Cond. index score	0.1	0.1	0.3	-0.5	0.5	0.5	-0.4	0.4	-0.2	0.2	0.2	-0.5	0.4	-0.0	0.1	0.1	0.4	-0.1	-0.5	0.4	0.1	-0.0	-0.3	-0.2	0.4	-0.4	0.0
Pavlov. Cond. latency score	0.1	0.1	0.5	-0.4	0.4	0.7	-0.3	0.3	-0.3	0.3	0.1	-0.4	0.3	-0.1	0.2	0.0	0.3	-0.0	-0.4	0.3	-0.0	-0.1	-0.1	-0.3	0.3	-0.3	0.1
Pavlov. Cond. lever contacts	0.1	0.1	0.2	-0.4	0.4	0.4	-0.3	0.3	-0.3	0.3	0.1	-0.4	0.3	-0.2	0.2	0.0	0.4	-0.1	-0.4	0.4	0.0	-0.1	-0.1	-0.3	0.4	-0.4	0.1
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.4	-0.7	0.6	0.4	-0.5	0.5	-0.1	0.1	0.3	-0.6	0.5	0.2	-0.0	0.2	0.6	-0.1	-0.6	0.6	0.3	0.1	-0.5	-0.1	0.6	-0.6	0.0
Delta distance traveled before/after self-admin	0.1	0.1	0.5	0.2	-0.1	0.3	0.2	-0.2	-0.6	0.6	-0.3	0.1	-0.1	-0.4	0.3	-0.2	-0.4	-0.1	0.1	-0.4	-0.4	-0.3	0.7	-0.6	-0.3	0.3	0.0
Distance moved, locomotor task time 1	0.1	0.1	1.3	0.3	0.2	0.1	-0.3	0.3	0.4	-0.4	-0.6	-0.2	-0.1	0.6	-0.2	-0.3	0.1	-1.1	-0.2	0.1	0.1	-0.2	-0.5	0.4	0.0	-0.1	-0.5
Distance moved, locomotor task time 2	0.1	0.1	1.0	0.1	-0.2	-1.0	0.2	-0.2	0.3	-0.3	0.3	0.2	-0.1	0.4	-0.2	0.5	-0.1	0.7	0.2	-0.1	0.3	0.5	-0.2	0.3	0.2	-0.0	0.5
Latency to leave start box in cocaine runway, F	0.1	0.2	1.1	0.2	-0.0	0.8	0.1	-0.1	0.2	-0.2	-0.3	0.0	-0.2	0.2	-0.4	-0.7	-0.4	-0.5	0.0	-0.4	-0.0	-0.4	0.2	0.2	-0.2	0.5	-1.0
Rb content in liver	0.1	0.1	1.3	-0.2	0.2	0.3	-0.2	0.2	0.1	-0.1	-0.5	-0.2	-0.1	0.3	-0.1	-0.6	0.2	-1.1	-0.2	0.2	-0.0	-0.4	-0.2	0.1	0.1	-0.2	-0.9
Total locomotion distance, hab. session 2	0.0	0.0	0.2	-0.1	0.2	0.4	-0.2	0.2	-0.1	0.1	0.3	-0.2	0.3	0.1	-0.1	0.2	0.2	0.4	-0.2	0.2	0.2	0.2	-0.1	-0.1	0.2	-0.2	0.2
Locomotion velocity, hab. session 2	0.0	0.0	0.2	-0.0	0.1	0.5	-0.1	0.1	-0.3	0.3	0.1	-0.1	0.1	0.0	0.1	0.0	0.1	0.1	-0.1	0.1	-0.0	0.0	0.1	-0.3	0.1	-0.1	0.1
Pavlov. Cond. magazine entry number	0.0	0.0	0.3	0.0	-0.2	-0.5	0.1	-0.1	0.0	-0.0	0.2	0.2	-0.1	-0.2	0.0	0.3	0.1	0.3	0.2	0.0	0.0	0.2	-0.0	0.0	0.1	-0.0	0.4
Bone: tissue strength	0.0	0.0	0.2	0.2	-0.1	-0.4	-0.0	0.0	0.4	-0.4	-0.0	0.1	-0.1	0.1	-0.3	0.1	-0.0	0.1	0.1	-0.0	0.2	0.2	-0.2	0.4	-0.0	0.1	-0.1
Bone: trabecular spacing	0.0	0.0	0.1	-0.1	0.1	-0.1	-0.3	0.3	0.1	-0.1	0.1	-0.1	0.2	0.1	0.1	0.2	0.1	0.1	-0.1	0.2	0.1	0.1	-0.1	0.1	0.3	-0.2	0.2
Delta ambulatory time before/after self-admin	0.0	0.0	0.3	0.1	0.0	0.5	0.0	-0.0	-0.1	0.1	0.1	-0.0	0.1	0.1	-0.1	0.2	-0.1	0.4	-0.0	-0.2	0.1	0.2	0.2	-0.1	-0.1	0.1	0.2

For each tested trait, stats based on TWAS chi² (squared Z-score) for the above models are shown. Avg chi² ratio is the mean chi² across all models for this gene, divided by the mean chi² across all models for all genes. Avg chi² is the mean chi² across all models for this gene. Max chi² is the highest chi² across all models for this gene.

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.