Hub : Genes

Chrna2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000017424 0.11 0.06 4.8e-05 0.06 0.07 0.06 0.06 5.1e-04 1.1e-04 3.3e-04 2.8e-04
2 Brain gene expression ENSRNOG00000017424 0.6 0.12 0.0e+00 0.51 0.58 0.58 0.59 4.9e-54 4.6e-65 6.3e-65 6.3e-67
3 Brain mRNA stability ENSRNOG00000017424 0.29 0.11 0.0e+00 0.28 0.29 0.29 0.29 6.9e-26 4.9e-27 4.7e-27 6.5e-27
4 Eye gene expression ENSRNOG00000017424 0.55 0.19 1.4e-06 0.33 0.43 0.38 0.38 4.3e-06 8.9e-08 5.6e-07 6.1e-07
5 IL gene expression ENSRNOG00000017424 0.17 0.11 5.5e-03 0.09 0.04 0.03 0.05 2.9e-03 4.5e-02 5.4e-02 3.0e-02
6 Liver gene expression ENSRNOG00000017424 0.06 0.04 2.3e-06 0.05 0.06 0.05 0.06 6.3e-06 8.2e-07 1.5e-06 1.0e-06
7 NAcc gene expression ENSRNOG00000017424 0.08 0.05 1.4e-05 0.06 0.04 0.04 0.05 3.8e-05 3.6e-04 5.1e-04 1.4e-04
8 PL gene expression ENSRNOG00000017424 0.2 0.09 1.2e-13 0.17 0.09 0.17 0.09 5.7e-13 4.1e-07 3.2e-13 2.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.61.92.41.41.41.11.41.6-1.21.51.4
BMI without tail0.10.20.7-0.4-0.4-0.8-0.30.30.80.1-0.2
Body weight0.10.50.90.70.81.00.60.4-0.90.30.7
Epididymis fat weight0.81.82.5-1.4-1.4-1.6-1.4-0.81.6-1.0-1.3
Glucose1.11.72.91.11.30.81.21.7-0.71.71.5
Heart weight0.00.00.0-0.00.10.1-0.10.10.1-0.00.2
Left kidney weight0.82.43.61.51.81.91.41.3-1.51.31.6
Right kidney weight0.20.51.2-0.7-0.40.0-0.9-0.90.4-1.1-0.5
Tail length0.82.53.2-1.7-1.6-1.4-1.8-1.51.6-1.7-1.3
Length with tail0.10.51.3-0.5-0.40.1-0.7-1.10.1-1.1-0.5
Length without tail1.02.14.51.51.62.11.40.5-2.00.61.1
Liver weight, left5.28.410.62.93.33.22.92.7-2.82.62.8
Liver weight, right2.44.04.82.02.22.22.11.8-2.01.71.9
Parametrial fat weight3.05.98.0-2.6-2.6-2.8-2.5-1.82.8-1.9-2.3
Retroperitoneal fat weight0.30.92.0-1.0-1.1-1.4-0.9-0.31.2-0.5-0.8
Intraocular pressure1.72.42.7-1.5-1.7-1.5-1.5-1.61.4-1.6-1.6
Extensor digitorum longus weight8.333.444.36.16.06.36.04.6-6.74.65.5
Soleus weight0.61.72.01.41.31.21.41.2-1.41.21.2
Tibialis anterior weight5.719.826.74.74.75.14.63.4-5.23.44.2
Tibia length1.44.06.7-2.0-1.7-0.9-2.1-2.61.6-2.5-2.0
Number of licking bursts0.10.10.20.1-0.1-0.30.10.40.10.40.2
Food consumed during 24 hour testing period0.20.20.90.30.70.90.30.2-0.30.20.5
Times rat made contact with spout0.00.00.1-0.00.20.00.00.30.20.30.2
Mean time between licks in bursts4.46.17.5-2.5-2.7-2.7-2.5-2.22.5-2.2-2.5
Mean num. licks in bursts0.00.00.1-0.00.30.4-0.1-0.1-0.0-0.10.0
Std. dev. time between licks in bursts8.410.011.6-3.1-3.3-2.8-3.1-3.42.6-3.4-3.4
Water consumed over 24 hours0.60.71.20.90.91.10.90.5-1.10.50.9
Indifference point 0 sec3.96.310.2-2.5-2.2-1.4-2.7-3.22.0-3.1-2.6
Indifference point AUC3.54.15.52.01.81.52.12.2-1.82.42.3
Indifference point function ln k1.01.42.6-1.1-0.9-0.6-1.2-1.40.9-1.6-1.4
Indifference point function log k1.01.42.6-1.1-0.9-0.6-1.2-1.40.9-1.6-1.4
Delay discounting total patch changes 0 sec3.15.08.6-2.2-1.8-1.1-2.4-2.91.7-2.9-2.3
Delay discounting total patch changes 12 sec0.40.61.2-0.7-0.7-0.4-0.8-1.10.5-0.9-0.7
Delay discounting total patch changes 18 sec0.20.30.4-0.6-0.5-0.5-0.7-0.50.6-0.5-0.4
Delay discounting total patch changes 24 sec0.50.61.6-0.6-0.50.0-0.7-1.30.3-1.1-0.8
Delay discounting total patch changes 6 sec0.10.20.3-0.4-0.4-0.3-0.5-0.50.4-0.5-0.3
Delay discounting time to switch 0 sec1.21.82.4-1.3-1.5-1.5-1.3-1.21.3-1.2-1.4
Delay discounting water rate 0 sec0.30.40.80.70.70.90.60.3-0.90.10.5
Delay discounting water rate 12 sec0.10.20.60.40.50.70.30.0-0.5-0.20.3
Delay discounting water rate 18 sec4.05.36.72.32.62.62.22.1-2.32.02.4
Delay discounting water rate 24 sec0.71.01.80.91.10.70.91.3-0.61.11.0
Delay discounting water rate 6 sec1.11.62.91.31.31.71.20.7-1.60.51.1
Locomotor activity0.40.62.0-0.2-0.20.8-0.4-1.4-0.6-1.3-0.6
Locomotor testing distance3.65.910.5-2.2-2.3-1.3-2.4-3.21.5-3.2-2.7
Locomotor testing rearing6.310.016.6-2.9-3.0-1.8-3.1-4.12.1-4.1-3.5
Light reinforcement 10.91.62.9-1.4-1.2-1.5-1.3-0.81.7-0.8-1.2
Light reinforcement 20.40.51.40.30.1-0.50.41.20.31.20.7
Reaction time number correct0.00.10.20.30.1-0.20.40.4-0.20.10.1
Reaction time mean minus median0.10.10.3-0.2-0.10.1-0.2-0.6-0.1-0.6-0.4
Reaction time mean minus median AUC0.00.10.2-0.1-0.00.1-0.1-0.40.0-0.4-0.4
Reaction time num false alarms0.40.51.0-0.6-0.5-0.3-0.6-0.90.5-1.0-0.9
Reaction time num false alarms AUC0.10.10.3-0.20.00.2-0.2-0.40.1-0.6-0.4
Reaction time trials correct on left0.00.10.20.30.1-0.20.40.4-0.20.10.1
Reaction time trials on left0.00.00.10.20.0-0.20.30.3-0.10.10.0
Reaction time mean0.00.10.10.20.20.30.20.0-0.40.10.2
Reaction time mean AUC0.10.10.20.30.20.40.2-0.1-0.50.00.1
Median of all reaction times0.10.10.20.40.30.30.40.3-0.40.30.4
Reaction time omissions2.12.83.4-1.7-1.7-1.8-1.6-1.41.8-1.5-1.8
Reaction time false alarm rate0.10.10.2-0.3-0.10.1-0.4-0.50.3-0.4-0.4
Reaction time premature initiation rate0.50.70.90.90.80.80.90.7-1.00.70.8
Reaction time premature initiations0.60.81.11.00.80.71.10.9-1.00.80.9
Std. dev. reaction times0.00.00.10.10.20.20.1-0.0-0.2-0.10.1
Reaction time trials completed0.00.00.10.20.0-0.20.30.3-0.10.10.0
Reaction time trials AUC0.00.00.10.20.0-0.20.30.3-0.10.10.1
Social response proportion0.10.10.50.10.1-0.50.20.70.30.50.1
Social responses4.25.56.9-2.4-2.3-2.6-2.3-1.82.6-2.1-2.5
Social time0.81.11.6-1.1-0.9-0.6-1.1-1.30.9-1.2-1.1
Conditioned locomotion0.10.10.5-0.2-0.4-0.7-0.20.00.30.0-0.3
Cocaine response after cond. corrected0.80.92.00.90.60.01.01.4-0.51.41.0
Cocaine response after cond. not corrected0.30.30.70.50.3-0.10.60.9-0.30.90.5
Cocaine response before conditioning1.41.72.7-1.3-1.0-0.6-1.4-1.60.9-1.6-1.4
Saline control response0.40.50.9-0.7-0.5-0.2-0.7-1.00.5-1.0-0.7
Condit. Reinf. active minus inactive responses0.60.70.9-0.8-0.9-0.7-0.8-0.90.7-0.9-1.0
Condit. Reinf. active-inactive response ratio0.30.30.30.50.50.40.60.6-0.50.60.5
Condit. Reinf. active responses1.11.51.6-1.2-1.3-1.1-1.2-1.21.2-1.2-1.2
Condit. Reinf. inactive responses3.44.24.6-2.1-2.1-2.0-2.1-2.02.0-2.0-2.0
Condit. Reinf. lever presses0.20.30.8-0.4-0.20.2-0.6-0.90.2-0.9-0.4
Condit. Reinf. lever reinforcers received0.60.91.0-1.0-0.9-0.7-1.0-1.00.9-1.0-0.9
Pavlov. Cond. lever latency0.70.92.2-0.9-1.1-1.5-0.7-0.31.2-0.3-0.9
Pavlov. Cond. magazine entry latency0.10.10.30.00.20.5-0.1-0.2-0.2-0.20.2
Pavlov. Cond. change in total contacts1.62.34.31.51.72.11.40.8-1.80.81.5
Pavlov. Cond. index score0.40.61.70.70.91.30.50.1-1.00.10.7
Pavlov. Cond. latency score0.20.31.00.40.51.00.2-0.2-0.7-0.20.4
Pavlov. Cond. lever contacts0.40.61.80.60.81.40.5-0.1-1.0-0.10.6
Pavlov. Cond. magazine entry number0.10.10.30.30.2-0.10.40.6-0.20.60.2
Pavlov. Cond. intertrial magazine entries7.79.911.5-3.2-3.3-3.4-3.2-2.73.3-2.7-3.2
Pavlov. Cond. lever-magazine prob. diff.0.50.71.80.80.91.30.60.2-1.10.20.8
Pavlov. Cond. response bias0.40.61.80.60.81.40.5-0.1-1.0-0.10.6
Conditioned reinforcement - actives0.80.81.5-1.0-1.0-1.2-0.9-0.41.2-0.5-0.6
Conditioned reinforcement - inactives1.82.12.5-1.5-1.5-1.4-1.6-1.41.5-1.3-1.2
Conditioned locomotion0.10.20.4-0.4-0.5-0.7-0.40.10.50.0-0.0
Intermittent access intake day 1-15 change0.30.30.4-0.6-0.6-0.6-0.6-0.50.6-0.5-0.6
Intermittent access intake escalation0.10.10.1-0.3-0.3-0.3-0.2-0.30.3-0.2-0.3
Intermittent access intake escalation 20.00.00.1-0.2-0.1-0.1-0.1-0.30.2-0.2-0.2
Intermitt. access day 1 inactive lever presses0.30.30.6-0.6-0.8-0.8-0.5-0.50.6-0.3-0.5
Intermitt. access day 15 inactive lever presses0.10.10.30.30.40.60.40.2-0.30.30.4
Intermitt. access escalation Index0.00.00.00.10.0-0.00.10.0-0.1-0.1-0.1
Intermittent access day 1 total infusions0.91.01.80.80.90.70.81.2-0.61.21.4
Intermittent access day 15 total infusions0.20.20.40.30.30.00.30.7-0.00.70.6
Intermittent access terminal intake (last 3 days)1.31.42.21.11.10.91.11.4-0.81.51.5
Intermittent access total infusions0.40.41.10.40.4-0.00.41.0-0.11.01.0
Intermittent access day 1 locomotion0.10.10.3-0.4-0.4-0.4-0.6-0.10.5-0.20.0
Intermittent access day 15 total locomotion0.20.20.60.20.2-0.10.10.70.10.70.7
Intermittent access total locomotion0.00.10.2-0.1-0.1-0.3-0.20.20.20.10.4
Intermittent access standard deviation0.50.50.80.60.90.90.60.6-0.60.60.7
Cocaine induced anxiety0.20.20.5-0.10.00.5-0.2-0.7-0.3-0.7-0.2
Post-drug Anxiety3.13.43.9-1.9-1.9-1.7-1.8-1.91.7-1.9-2.0
Baseline Anxiety2.82.93.6-1.8-1.8-1.9-1.7-1.41.9-1.4-1.8
Lifetime Intake0.20.20.60.20.2-0.10.20.7-0.00.60.8
Incentive Sensitization - Responses0.30.30.60.40.60.60.30.5-0.30.50.8
Incentive Sensitization - Breakpoint0.10.10.40.20.40.50.10.3-0.10.30.6
Progressive ratio test 1 active lever presses1.92.03.41.31.30.81.31.9-0.91.81.7
Progressive ratio test 1 breakpoint1.91.93.51.21.30.81.31.9-0.81.81.7
Progressive ratio test 1 inactive lever presses0.40.40.8-0.7-0.7-0.9-0.6-0.40.9-0.4-0.5
Progressive ratio test 2 active lever presses1.31.42.71.01.10.60.91.6-0.51.51.6
Progressive ratio test 2 breakpoint1.21.32.40.91.10.70.91.5-0.61.41.6
Progressive ratio test 2 inactive lever presses0.10.10.50.20.30.10.10.60.00.40.7
Total sessions with >9 infusions0.40.40.9-0.6-0.8-1.0-0.6-0.30.7-0.3-0.4
Short access day 1 total inactive lever presses1.11.22.70.90.90.60.71.3-0.61.41.7
Short access day 10 total inactive lever presses0.30.30.6-0.6-0.6-0.7-0.5-0.40.8-0.2-0.5
Short access day 1 total infusions0.40.41.00.50.40.00.51.0-0.40.80.9
Short access day 10 total infusions0.40.40.80.60.70.80.50.5-0.70.50.9
Short access total infusions0.20.20.60.30.40.30.30.6-0.30.50.8
Short access day 1 locomotion0.10.10.20.20.30.50.1-0.0-0.4-0.10.2
Short access day 10 total locomotion0.60.71.0-0.9-0.9-0.8-1.0-0.80.8-0.8-0.6
Short access total locomotion0.70.71.0-0.9-0.9-0.7-1.0-0.80.8-0.9-0.7
Compulsive drug intake0.50.50.7-0.7-0.6-0.5-0.7-0.80.5-0.8-0.9
One hour access (0.3 mA shock)0.10.20.40.30.40.30.20.5-0.10.60.7
One hour access (shock baseline)0.50.61.20.70.60.50.60.9-0.61.01.1
Number of responses in last shaping day0.10.10.30.00.20.5-0.1-0.4-0.3-0.4-0.1
Context. condit. distance diff. score0.50.61.80.1-0.0-0.90.31.30.61.30.6
Locomotion velocity, session 10.60.71.2-0.7-0.8-0.6-0.7-1.10.4-1.1-1.1
Locomotion distance, session 11.31.73.4-1.1-1.2-0.6-1.2-1.80.6-1.8-1.5
Locomotion velocity, session 20.50.61.5-0.6-0.6-0.1-0.6-1.20.2-1.2-1.0
Locomotion distance, session 21.92.75.3-1.4-1.4-0.7-1.5-2.30.8-2.3-2.0
Locomotion velocity, session 31.82.12.41.51.61.31.51.5-1.31.41.5
Locomotion distance, session 30.40.40.70.60.70.40.70.8-0.40.80.7
Stereotopy head waving bouts, day 30.10.10.30.30.20.40.3-0.1-0.5-0.10.1
Stereotopy head waving duration, day 31.11.42.41.21.21.51.10.7-1.50.61.1
Locomotion velocity, session 70.70.82.2-0.5-0.5-1.5-0.30.91.31.00.1
Locomotion distance, session 71.72.15.0-1.5-1.4-2.2-1.3-0.22.2-0.1-1.0
Stereotopy head waving bouts, day 70.91.12.01.11.01.41.00.5-1.40.40.9
Stereotopy head waving duration, day 72.22.84.31.81.72.01.71.2-2.11.11.6
Locomotion velocity, session 80.30.40.50.60.50.30.70.7-0.50.70.6
Locomotion distance, session 80.40.51.0-0.8-0.8-1.0-0.7-0.40.8-0.4-0.7
Degree of sensitization distance3.63.76.7-2.0-2.0-2.6-1.9-0.92.6-0.8-1.5
Degree of sensitization stereotypy1.21.31.91.21.21.41.10.8-1.40.81.1
Condit. Reinf. active minus inactive responses0.00.10.10.00.00.3-0.1-0.3-0.3-0.4-0.0
Condit. Reinf. active-inactive response ratio0.40.40.70.70.50.60.70.5-0.90.50.6
Condit. Reinf. active responses0.60.81.6-0.8-0.8-0.4-0.9-1.20.5-1.3-0.9
Condit. Reinf. inactive responses3.54.15.4-2.1-1.9-1.4-2.2-2.31.8-2.3-2.1
Incentive salience index mean0.10.20.40.10.10.6-0.1-0.6-0.4-0.6-0.1
Condit. Reinf. lever presses0.30.41.2-0.3-0.30.3-0.5-1.1-0.1-1.1-0.6
Time in familiar zone, hab. session 10.20.20.3-0.4-0.4-0.5-0.4-0.20.5-0.3-0.3
Time in novel zone, hab. session 12.82.83.11.71.81.61.71.6-1.61.71.7
Total zone transitions, hab. session 10.10.10.3-0.1-0.00.3-0.1-0.5-0.2-0.5-0.3
Total locomotion distance, hab. session 10.81.12.0-1.0-0.9-0.5-1.0-1.40.6-1.4-1.2
Locomotion velocity, hab. session 12.02.84.8-1.6-1.6-1.0-1.6-2.11.1-2.2-1.9
Time in familiar zone, hab. session 20.30.30.60.50.2-0.10.70.8-0.30.80.4
Time in novel zone, hab. session 20.20.20.4-0.3-0.20.1-0.5-0.60.1-0.6-0.3
Total zone transitions, hab. session 20.20.30.70.30.30.80.2-0.5-0.9-0.5-0.0
Total locomotion distance, hab. session 20.20.20.6-0.2-0.30.0-0.3-0.7-0.1-0.8-0.5
Locomotion velocity, hab. session 20.10.20.6-0.0-0.10.3-0.1-0.7-0.4-0.8-0.4
Novel to familiar place preference ratio0.40.40.7-0.6-0.5-0.3-0.7-0.80.6-0.8-0.6
Novelty place preference0.60.61.0-0.8-0.7-0.5-0.8-0.90.7-1.0-0.8
Time in novel zone, NPP test0.50.51.0-0.7-0.6-0.4-0.7-0.90.5-1.0-0.8
Total zone transitions, NPP test1.31.93.0-1.3-1.3-0.9-1.3-1.70.9-1.7-1.6
Total locomotion distance, NPP test6.08.39.7-2.9-2.9-2.5-2.9-3.02.6-3.0-3.1
Locomotion velocity, NPP test4.76.77.6-2.6-2.6-2.3-2.6-2.72.4-2.7-2.8
Pavlov. Cond. lever latency0.10.10.20.0-0.1-0.40.10.40.10.50.1
Pavlov. Cond. magazine entry latency0.00.10.20.10.40.40.10.1-0.10.10.2
Pavlov. Cond. change in total contacts0.91.02.61.01.11.60.80.3-1.30.20.8
Pavlov. Cond. index score0.20.30.80.50.70.90.40.1-0.60.00.4
Pavlov. Cond. latency score0.10.10.50.30.50.70.2-0.0-0.4-0.10.3
Pavlov. Cond. lever contacts0.10.10.50.20.40.70.1-0.1-0.4-0.10.2
Pavlov. Cond. magazine entry number0.50.71.3-0.8-1.0-1.1-0.7-0.50.9-0.5-0.8
Pavlov. Cond. intertrial magazine entries1.01.21.8-1.1-1.0-0.7-1.1-1.40.8-1.4-1.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.30.70.91.10.60.3-0.80.20.7
Pavlov. Cond. response bias0.81.01.81.01.21.30.90.8-1.00.71.1
Bone: apparent density1.62.73.0-1.7-1.7-1.7-1.6-1.51.7-1.5-1.7
Bone surface1.11.92.1-1.4-1.4-1.2-1.4-1.51.3-1.5-1.4
Bone volume1.32.12.3-1.5-1.5-1.3-1.5-1.51.4-1.5-1.5
Bone: connectivity density3.25.06.3-2.3-2.4-2.5-2.2-1.92.4-1.9-2.3
Bone: cortical apparent density0.91.22.30.91.00.51.01.5-0.41.51.2
Bone: cortical area0.10.10.40.30.40.60.20.1-0.30.10.4
Bone: cortical porosity0.30.30.90.50.50.90.4-0.2-0.9-0.20.2
Bone: cortical porosity0.20.30.90.40.50.90.3-0.2-0.8-0.20.2
Bone: cortical thickness0.30.50.70.60.80.80.60.6-0.50.60.8
Bone: cortical thickness0.40.51.00.60.60.30.71.0-0.31.00.8
Bone: cortical tissue density1.11.42.71.11.10.61.21.7-0.51.71.3
Bone: elastic displacement1.01.22.2-1.0-1.0-0.5-1.0-1.50.6-1.5-1.1
Bone: elastic work1.11.53.3-1.0-0.9-0.2-1.2-1.80.5-1.8-1.3
Bone: endosteal estimation0.10.10.3-0.4-0.3-0.2-0.4-0.50.3-0.5-0.4
Bone: endosteal perimeter0.61.22.0-1.0-1.0-0.6-1.0-1.40.7-1.4-1.2
Bone: final force0.10.10.30.30.40.50.30.2-0.30.20.3
Bone: final moment0.00.10.30.10.30.50.1-0.1-0.2-0.10.1
Bone: marrow area0.10.20.4-0.5-0.4-0.3-0.5-0.60.4-0.6-0.5
Bone: maximum diameter0.40.71.20.81.01.10.80.7-0.90.70.8
Bone: maximum force0.20.30.80.50.70.90.50.2-0.60.20.5
Bone: maximum moment0.10.20.70.20.40.80.2-0.2-0.4-0.20.2
Bone: minimum diameter0.10.10.60.10.30.70.0-0.3-0.3-0.30.1
Bone: periosteal estimation0.00.00.1-0.2-0.00.2-0.2-0.30.1-0.3-0.1
Bone: periosteal perimeter0.30.40.8-0.6-0.6-0.3-0.6-0.90.4-0.9-0.7
Bone: post-yield work1.01.42.71.01.10.61.11.7-0.51.71.4
Bone: stiffness0.50.80.90.91.00.90.90.8-0.80.80.9
Bone: tissue strength0.30.30.4-0.5-0.4-0.2-0.5-0.70.4-0.7-0.6
Bone: trabecular number2.33.64.2-2.0-2.0-2.0-1.9-1.62.0-1.6-1.9
Bone: trabecular spacing1.92.43.31.61.61.71.61.2-1.81.21.5
Bone: trabecular thickness0.40.50.6-0.8-0.7-0.6-0.8-0.70.8-0.7-0.7
Bone: trabecular tissue density0.91.31.71.21.21.31.10.9-1.30.91.2
Breakpoint value in progressive ratio session0.40.50.7-0.6-0.8-0.7-0.5-0.70.5-0.8-0.8
Distance traveled before self-admin0.50.51.20.80.60.90.70.3-1.10.20.6
Distance traveled after self-admin1.01.11.71.20.91.01.10.8-1.30.71.2
Delta time in closed arm before/after self-admin0.20.20.3-0.5-0.5-0.5-0.5-0.40.5-0.3-0.3
Delta time in open arm before/after self-admin0.20.20.4-0.4-0.5-0.7-0.3-0.10.5-0.3-0.3
Diff in mean of infusions in LGA sessions0.20.20.50.40.40.60.40.0-0.7-0.20.1
Extinction: sum of active levers before priming1.92.02.7-1.5-1.4-1.6-1.4-1.11.6-1.3-1.3
Active lever presses in extinction session 60.10.10.3-0.2-0.1-0.3-0.20.10.5-0.1-0.0
Delta distance traveled before/after self-admin1.11.21.41.11.10.91.21.1-1.01.01.2
Delta ambulatory time before/after self-admin0.91.01.21.01.00.91.00.9-1.00.91.1
Time in closed arm before self-admin0.50.50.80.80.70.80.80.6-0.90.50.5
Time in closed arm after self-admin0.00.00.00.0-0.1-0.0-0.0-0.2-0.2-0.2-0.2
Time in open arm before self-admin0.20.20.3-0.4-0.4-0.3-0.4-0.50.2-0.6-0.5
Time in open arm after self-admin0.20.30.6-0.5-0.6-0.8-0.5-0.20.6-0.4-0.4
Sum of active levers in priming session hrs 5-60.20.20.7-0.4-0.4-0.8-0.30.20.7-0.0-0.1
Time to tail flick, vehicle, before self-admin0.10.10.2-0.4-0.1-0.1-0.4-0.30.4-0.4-0.4
Time to tail flick, vehicle, after self-admin1.41.52.11.41.21.11.51.1-1.41.10.9
Time to tail flick, test, before self-admin0.70.70.9-0.9-0.9-0.7-1.0-0.90.8-0.6-0.7
Time to tail flick, test, after self-admin3.94.07.1-2.1-2.2-2.7-1.9-1.12.5-0.8-1.9
Delta time to tail flick, vehicle, before/after SA0.90.81.40.90.80.51.01.1-0.71.20.9
Delta time to tail flick, test, before/after SA0.50.41.4-0.5-0.5-1.2-0.30.31.00.3-0.5
Ambulatory time before self-admin0.30.30.60.60.50.70.50.3-0.80.20.6
Ambulatory time after self-admin1.61.72.71.41.31.41.31.0-1.70.91.4
Total heroin consumption1.61.93.21.41.61.81.41.0-1.50.91.2
Area under the delay curve0.10.10.30.30.40.40.30.3-0.30.30.5
Delay disc. indifference point, 0s delay2.02.23.1-1.4-1.5-1.2-1.5-1.71.1-1.8-1.5
Delay disc. indifference point, 16s delay0.30.30.60.40.50.40.40.7-0.30.60.7
Delay disc. indifference point, 2s delay0.40.51.4-0.4-0.6-0.1-0.5-1.2-0.0-1.0-0.8
Delay disc. indifference point, 24s delay0.60.60.80.80.70.60.70.9-0.70.80.9
Delay disc. indifference point, 4s delay1.21.21.41.11.11.21.11.0-1.21.01.2
Delay disc. indifference point, 8s delay0.40.50.90.60.70.70.50.7-0.40.70.9
Delay discount exponential model param0.60.60.9-0.7-0.8-0.8-0.7-0.70.7-0.7-1.0
Delay discount hyperbolic model param0.60.60.9-0.8-0.8-0.9-0.7-0.60.9-0.6-0.9
Fecal boli incidents, locomotor time 12.32.43.21.51.71.81.41.5-1.31.41.8
Change in fecal boli incidents, locomotor task0.10.10.2-0.2-0.2-0.5-0.1-0.10.2-0.1-0.4
Time >=10cm from walls, locomotor time 11.31.31.7-1.2-1.0-0.9-1.2-1.21.1-1.0-1.3
Bouts of movement, locomotor time 11.01.11.81.20.80.91.21.0-1.30.81.0
Total resting periods, locomotor time 11.61.82.41.51.11.01.51.4-1.51.31.3
Rest time, locomotor task time 11.92.12.81.51.41.11.61.7-1.41.41.4
Distance moved, locomotor task time 11.61.72.1-1.4-1.3-1.1-1.4-1.41.4-1.2-1.3
Vertical activity count, locomotor time 10.60.62.0-0.6-0.50.1-0.8-1.40.2-1.0-0.9
Time >=10cm from walls, locomotor time 20.10.10.30.30.50.50.30.1-0.40.30.1
Bouts of movement, locomotor time 21.51.62.11.41.20.91.51.4-1.31.21.0
Total resting periods, locomotor time 23.13.34.51.91.81.42.02.1-1.71.81.7
Rest time, locomotor task time 28.19.413.13.03.12.53.03.6-2.53.33.4
Distance moved, locomotor task time 23.84.46.6-2.1-1.9-1.5-2.2-2.61.8-2.2-2.3
Vertical activity count, locomotor time 21.51.74.0-1.1-1.0-0.3-1.2-2.00.5-1.7-1.5
Weight adjusted by age0.40.41.30.60.71.10.5-0.1-0.9-0.20.2
Seeking ratio, delayed vs. immediate footshock1.72.02.8-1.4-1.4-1.1-1.4-1.71.1-1.7-1.4
Locomotion in novel chamber0.00.00.10.10.30.20.10.3-0.00.30.3
Locomotion in novel chamber post-restriction0.81.01.21.01.11.11.00.8-1.10.81.1
Progressive ratio0.40.50.70.70.70.80.70.5-0.90.60.6
Food seeking constrained by brief footshock1.31.52.91.30.90.41.41.7-1.01.51.3
Seeking ratio, punishment vs. effort0.10.20.40.40.3-0.10.40.7-0.20.60.5
Run reversals in cocaine runway, females1.01.01.4-1.1-1.1-1.2-1.1-0.71.1-0.6-0.7
Run reversals in cocaine runway, males7.57.310.12.73.03.22.62.2-2.82.12.9
Latency to leave start box in cocaine runway1.21.31.91.21.21.21.31.0-1.40.81.0
Latency to leave start box in cocaine runway, F2.73.04.01.81.81.91.81.4-2.01.31.6
Latency to leave start box in cocaine runway, M1.11.11.4-1.0-1.1-1.1-1.0-0.90.9-1.1-1.2
Cd content in liver0.10.20.2-0.4-0.4-0.3-0.5-0.40.4-0.4-0.3
Co content in liver2.52.93.31.81.71.51.81.6-1.71.71.8
Cu content in liver1.21.41.61.21.21.11.21.1-1.21.21.3
Fe content in liver0.60.71.1-0.9-0.8-0.9-0.9-0.51.1-0.5-0.7
K content in liver0.60.61.1-0.8-0.9-1.1-0.8-0.40.9-0.5-0.7
Mg content in liver0.50.50.8-0.7-0.8-0.9-0.7-0.40.8-0.5-0.7
Mn content in liver3.13.54.0-1.9-2.0-2.0-1.9-1.61.9-1.7-1.9
Na content in liver0.60.62.10.40.71.40.3-0.6-1.1-0.7-0.0
Rb content in liver0.10.10.2-0.00.0-0.30.00.50.30.40.3
Se content in liver3.64.36.6-2.0-2.1-1.5-2.1-2.61.4-2.5-2.2
Sr content in liver1.41.21.5-1.1-1.2-1.1-1.1-1.11.0-1.1-1.2
Zn content in liver0.30.31.00.40.51.00.3-0.4-0.8-0.40.2