Marchf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017396 0.03 0.02 2.7e-03 0.02 0.01 0 0.01 3.9e-03 1.6e-02 1.1e-01 1.4e-02
2 Adipose mRNA stability ENSRNOG00000017396 0.05 0.03 3.7e-06 0.04 0.04 0.03 0.03 2.5e-05 4.8e-05 4.5e-04 1.0e-04
3 BLA gene expression ENSRNOG00000017396 0.22 0.11 5.2e-11 0.2 0.2 0.2 0.2 4.0e-11 8.2e-11 3.9e-11 4.6e-11
4 Brain gene expression ENSRNOG00000017396 0.27 0.11 0.0e+00 0.27 0.26 0.27 0.27 3.6e-25 1.7e-24 1.3e-24 4.8e-25
5 IL gene expression ENSRNOG00000017396 0.21 0.12 3.3e-04 0.07 0.07 0.07 0.06 1.1e-02 1.1e-02 7.4e-03 1.6e-02
6 LHb gene expression ENSRNOG00000017396 0.21 0.12 3.5e-04 0.02 0.12 0.09 0.07 9.3e-02 7.6e-04 3.5e-03 8.1e-03
7 Liver mRNA stability ENSRNOG00000017396 0.05 0.04 2.1e-04 0.02 0.02 0.02 0.01 1.7e-03 4.2e-03 3.8e-03 8.8e-03
8 NAcc gene expression ENSRNOG00000017396 0.12 0.08 2.0e-08 0.1 0.12 0.11 0.11 3.4e-08 3.1e-09 2.2e-08 1.7e-08
9 OFC gene expression ENSRNOG00000017396 0.12 0.09 8.7e-03 0.09 0.06 -0 0.06 3.9e-03 1.5e-02 4.2e-01 1.6e-02
10 PL gene expression ENSRNOG00000017396 0.21 0.12 1.1e-11 0.16 0.15 0.15 0.16 6.5e-12 2.7e-11 1.0e-11 5.2e-12
11 PL mRNA stability ENSRNOG00000017396 0.06 0.04 2.5e-04 0.04 0.04 0.03 0 2.6e-04 7.6e-04 2.7e-03 1.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.10.41.8-1.4-0.6-0.3-0.5-0.4-0.60.6-0.5-0.5-0.50.7
BMI without tail0.10.21.2-1.1-0.3-0.0-0.4-0.0-0.50.3-0.4-0.3-0.30.3
Body weight1.25.06.6-0.7-2.6-2.3-2.4-2.5-1.52.6-2.2-2.5-2.51.8
Epididymis fat weight0.20.40.70.8-0.8-0.5-0.5-0.80.30.8-0.1-0.5-0.60.4
Glucose0.20.30.5-0.2-0.6-0.7-0.7-0.3-0.40.6-0.7-0.6-0.6-0.1
Heart weight0.30.41.3-1.1-0.30.0-0.00.8-1.10.3-0.9-0.1-0.2-0.5
Left kidney weight0.61.62.5-0.3-1.6-1.4-1.5-1.3-0.71.6-1.4-1.5-1.50.3
Right kidney weight0.20.50.80.2-0.8-0.8-0.9-0.6-0.20.8-0.9-0.9-0.8-0.6
Tail length0.51.42.20.7-1.2-1.3-1.4-1.4-0.41.2-1.2-1.5-1.40.6
Length with tail1.34.97.00.6-2.6-2.4-2.4-2.6-1.12.6-2.2-2.6-2.61.5
Length without tail1.73.67.21.1-2.3-2.1-1.9-2.7-0.42.3-1.4-2.1-2.11.5
Liver weight, left2.84.56.80.5-2.5-2.3-2.4-2.6-0.92.5-1.8-2.4-2.41.7
Liver weight, right0.71.12.31.3-1.0-1.1-1.2-1.50.31.0-0.5-1.0-1.00.8
Parametrial fat weight0.30.61.0-0.1-0.8-1.0-0.9-0.9-0.30.8-0.8-1.0-0.90.5
Retroperitoneal fat weight0.10.40.60.3-0.7-0.7-0.7-0.7-0.40.7-0.6-0.7-0.70.3
Intraocular pressure0.40.51.0-0.6-0.6-0.6-0.7-0.4-1.00.6-0.9-0.7-0.70.9
Extensor digitorum longus weight0.41.54.12.0-1.1-1.1-1.2-1.70.71.1-0.3-1.1-1.10.9
Soleus weight1.03.04.8-1.6-1.7-1.7-1.6-1.3-2.21.7-2.1-1.7-1.71.6
Tibialis anterior weight0.51.76.22.5-0.8-1.1-0.9-2.11.20.80.2-0.9-0.91.4
Tibia length0.10.40.9-0.2-0.6-0.5-0.8-0.4-0.80.6-1.0-0.8-0.70.1
Number of licking bursts2.83.44.71.01.91.82.01.62.0-1.92.21.91.9-1.6
Food consumed during 24 hour testing period0.10.10.30.3-0.20.2-0.20.1-0.00.2-0.2-0.1-0.2-0.5
Times rat made contact with spout0.40.41.21.00.40.70.4-0.31.1-0.40.90.30.30.2
Mean time between licks in bursts0.81.02.9-0.81.00.91.01.7-0.0-1.00.41.01.0-1.4
Mean num. licks in bursts1.72.02.6-0.3-1.6-1.3-1.5-1.6-1.21.6-1.4-1.6-1.61.6
Std. dev. time between licks in bursts1.92.34.5-0.41.61.51.62.10.7-1.61.21.71.7-1.9
Water consumed over 24 hours1.01.24.12.00.70.90.80.01.8-0.71.40.70.7-0.4
Indifference point 0 sec0.10.10.4-0.5-0.2-0.0-0.20.3-0.60.2-0.6-0.1-0.1-0.3
Indifference point AUC0.91.02.01.10.90.90.80.91.2-0.91.00.90.9-1.4
Indifference point function ln k1.52.12.7-0.7-1.5-1.5-1.4-1.5-1.41.5-1.6-1.6-1.51.7
Indifference point function log k1.52.12.7-0.7-1.5-1.5-1.4-1.5-1.41.5-1.6-1.6-1.51.7
Delay discounting total patch changes 0 sec0.10.20.6-0.5-0.3-0.1-0.30.2-0.80.3-0.7-0.2-0.3-0.2
Delay discounting total patch changes 12 sec1.21.62.60.41.21.41.31.60.9-1.21.21.41.4-1.6
Delay discounting total patch changes 18 sec0.20.30.60.50.50.80.50.60.4-0.50.50.50.5-0.7
Delay discounting total patch changes 24 sec0.10.20.70.80.20.20.00.30.4-0.20.10.20.2-0.7
Delay discounting total patch changes 6 sec0.50.82.20.10.70.90.81.50.2-0.70.40.90.8-1.5
Delay discounting time to switch 0 sec1.01.62.00.51.41.31.41.21.1-1.41.41.41.4-1.0
Delay discounting water rate 0 sec0.40.60.90.4-1.0-0.7-0.8-0.8-0.61.0-0.8-0.9-0.90.7
Delay discounting water rate 12 sec0.71.11.5-0.9-1.1-0.9-1.0-0.9-1.11.1-1.2-1.2-1.20.8
Delay discounting water rate 18 sec1.21.62.4-0.2-1.6-1.1-1.3-1.4-0.91.6-1.3-1.4-1.51.2
Delay discounting water rate 24 sec1.52.03.10.6-1.8-1.5-1.5-1.7-0.61.8-1.2-1.6-1.71.3
Delay discounting water rate 6 sec0.20.20.7-0.4-0.4-0.3-0.3-0.1-0.80.4-0.7-0.5-0.50.3
Locomotor activity0.40.61.0-0.00.91.00.81.00.5-0.90.80.90.9-0.5
Locomotor testing distance0.60.91.5-0.31.11.01.01.20.5-1.10.81.01.1-0.9
Locomotor testing rearing0.00.10.20.3-0.2-0.4-0.2-0.40.30.20.1-0.1-0.10.4
Light reinforcement 10.20.42.2-1.5-0.2-0.4-0.2-0.3-0.80.2-0.4-0.2-0.21.0
Light reinforcement 23.04.05.5-1.22.32.02.32.31.0-2.32.02.32.3-1.2
Reaction time number correct0.81.12.5-0.2-0.9-1.4-0.9-1.4-0.70.9-0.8-1.0-1.01.6
Reaction time mean minus median0.60.82.3-1.4-0.7-0.6-0.6-0.1-1.50.7-1.2-0.7-0.70.2
Reaction time mean minus median AUC0.20.31.5-1.2-0.00.10.10.6-1.10.0-0.6-0.1-0.0-0.2
Reaction time num false alarms0.50.61.61.0-0.8-0.8-0.7-1.30.40.8-0.2-0.8-0.80.7
Reaction time num false alarms AUC0.30.40.90.9-0.6-0.6-0.6-0.90.40.6-0.2-0.6-0.60.3
Reaction time trials correct on left0.81.12.5-0.2-0.9-1.4-0.9-1.4-0.70.9-0.8-1.0-1.01.6
Reaction time trials on left0.81.12.3-0.1-0.9-1.4-0.9-1.4-0.70.9-0.8-1.0-1.01.5
Reaction time mean1.31.73.6-0.61.41.51.21.80.4-1.40.81.31.3-1.9
Reaction time mean AUC1.72.24.3-0.51.61.61.42.10.5-1.61.01.51.5-2.1
Median of all reaction times2.22.95.0-0.41.91.91.62.20.9-1.91.31.81.8-2.2
Reaction time omissions0.00.10.5-0.10.10.0-0.00.2-0.2-0.1-0.3-0.10.0-0.7
Reaction time false alarm rate0.10.10.60.8-0.3-0.2-0.3-0.40.50.30.0-0.3-0.3-0.1
Reaction time premature initiation rate1.21.72.5-0.4-1.6-1.1-1.4-1.5-0.81.6-1.2-1.4-1.51.2
Reaction time premature initiations2.94.15.6-0.6-2.3-2.1-2.2-2.4-1.42.3-1.9-2.2-2.22.1
Std. dev. reaction times0.40.52.2-1.50.10.30.10.9-1.0-0.1-0.60.10.1-0.9
Reaction time trials completed0.81.12.3-0.1-0.9-1.4-0.9-1.4-0.70.9-0.8-1.0-1.01.5
Reaction time trials AUC0.40.61.70.1-0.7-1.1-0.6-1.1-0.30.7-0.5-0.7-0.71.3
Social response proportion0.20.21.0-1.00.1-0.30.30.2-0.5-0.10.00.30.20.6
Social responses1.01.33.3-1.5-0.9-1.2-0.8-0.4-1.80.9-1.4-0.8-0.91.1
Social time0.60.71.1-0.10.90.60.91.00.7-0.90.91.11.0-1.0
Conditioned locomotion0.50.61.00.1-0.9-0.8-0.8-1.0-0.30.9-0.5-0.7-0.81.0
Cocaine response after cond. corrected0.00.10.4-0.6-0.20.0-0.10.0-0.30.2-0.2-0.0-0.10.0
Cocaine response after cond. not corrected0.10.10.20.2-0.5-0.3-0.4-0.50.00.5-0.2-0.4-0.40.1
Cocaine response before conditioning0.20.21.31.10.00.00.1-0.20.8-0.00.3-0.00.0-0.5
Saline control response0.30.41.51.10.30.40.4-0.11.2-0.31.00.50.4-0.0
Condit. Reinf. active minus inactive responses0.40.51.71.3-0.6-0.7-0.6-1.00.60.6-0.0-0.6-0.60.4
Condit. Reinf. active-inactive response ratio0.10.10.80.90.1-0.20.1-0.20.7-0.10.40.10.1-0.1
Condit. Reinf. active responses1.52.13.30.5-1.6-1.6-1.6-1.8-0.61.6-1.3-1.6-1.61.2
Condit. Reinf. inactive responses1.92.33.0-0.6-1.7-1.4-1.7-1.5-1.31.7-1.7-1.7-1.71.0
Condit. Reinf. lever presses0.10.10.3-0.1-0.5-0.3-0.4-0.3-0.30.5-0.4-0.4-0.50.2
Condit. Reinf. lever reinforcers received0.81.22.00.6-1.3-1.2-1.2-1.4-0.31.3-0.9-1.2-1.20.9
Pavlov. Cond. lever latency0.10.10.70.8-0.1-0.2-0.1-0.50.50.10.2-0.2-0.10.4
Pavlov. Cond. magazine entry latency0.60.71.30.80.60.90.90.71.1-0.60.90.80.7-1.1
Pavlov. Cond. change in total contacts0.20.20.91.00.10.40.30.10.8-0.10.60.30.2-0.6
Pavlov. Cond. index score0.10.10.30.5-0.10.20.20.10.40.10.20.10.0-0.5
Pavlov. Cond. latency score0.00.00.20.5-0.2-0.00.0-0.10.20.20.0-0.1-0.1-0.3
Pavlov. Cond. lever contacts0.00.10.2-0.4-0.1-0.0-0.00.2-0.30.1-0.3-0.0-0.1-0.3
Pavlov. Cond. magazine entry number1.51.83.0-1.3-1.2-1.3-1.4-1.1-1.61.2-1.4-1.2-1.21.7
Pavlov. Cond. intertrial magazine entries0.70.91.90.6-1.0-0.9-1.0-1.40.01.0-0.5-1.0-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.70.10.30.30.10.6-0.10.40.20.1-0.6
Pavlov. Cond. response bias0.40.51.30.50.60.70.70.70.7-0.60.60.70.6-1.1
Conditioned reinforcement - actives2.92.83.3-0.7-1.8-1.8-1.6-1.8-1.61.8-1.8-1.8-1.81.7
Conditioned reinforcement - inactives2.62.93.4-1.1-1.8-1.6-1.6-1.7-1.91.8-1.8-1.8-1.81.8
Conditioned locomotion1.72.04.2-1.6-1.3-1.3-1.3-0.9-2.01.3-1.8-1.3-1.31.3
Intermittent access intake day 1-15 change4.14.17.1-2.3-1.8-2.1-2.0-1.4-2.71.8-2.4-1.9-1.81.9
Intermittent access intake escalation4.24.17.6-2.5-1.8-2.0-2.0-1.2-2.81.8-2.5-1.9-1.81.7
Intermittent access intake escalation 21.71.73.7-1.6-1.0-1.3-1.2-0.7-1.91.0-1.7-1.1-1.11.2
Intermitt. access day 1 inactive lever presses0.10.20.7-0.80.30.30.30.3-0.4-0.30.00.20.30.5
Intermitt. access day 15 inactive lever presses1.92.15.1-2.0-1.1-1.1-1.1-0.6-2.31.1-1.8-1.2-1.21.5
Intermitt. access escalation Index0.30.21.21.10.30.10.30.10.8-0.30.50.30.3-0.5
Intermittent access day 1 total infusions0.91.01.90.4-1.2-1.1-0.9-1.4-0.51.2-0.8-1.1-1.11.2
Intermittent access day 15 total infusions6.37.19.4-1.8-2.7-2.8-2.6-2.5-2.92.7-3.1-2.8-2.72.3
Intermittent access terminal intake (last 3 days)3.53.85.1-1.5-1.9-2.1-1.8-1.8-2.31.9-2.2-2.0-2.01.9
Intermittent access total infusions2.62.83.6-0.6-1.8-1.9-1.6-1.9-1.51.8-1.7-1.8-1.81.7
Intermittent access day 1 locomotion0.60.60.80.4-0.9-0.8-0.7-0.9-0.40.9-0.7-0.8-0.80.9
Intermittent access day 15 total locomotion2.12.34.1-1.6-1.4-1.4-1.4-1.0-2.01.4-1.8-1.4-1.41.4
Intermittent access total locomotion0.30.41.0-0.1-0.6-0.7-0.5-0.8-0.50.6-0.5-0.6-0.61.0
Intermittent access standard deviation2.12.33.5-1.5-1.5-1.6-1.4-1.1-1.91.5-1.9-1.5-1.50.9
Cocaine induced anxiety0.50.61.70.90.70.50.70.11.3-0.71.10.70.7-0.2
Post-drug Anxiety0.60.61.0-0.00.90.80.90.70.7-0.91.00.90.9-0.3
Baseline Anxiety0.10.10.6-0.70.00.10.00.5-0.6-0.0-0.30.10.1-0.2
Lifetime Intake2.12.32.9-0.6-1.6-1.7-1.4-1.6-1.41.6-1.6-1.6-1.61.6
Incentive Sensitization - Responses5.55.57.4-1.8-2.2-2.5-2.2-2.1-2.72.2-2.7-2.3-2.32.6
Incentive Sensitization - Breakpoint5.85.87.6-1.9-2.3-2.5-2.3-2.2-2.82.3-2.7-2.4-2.32.6
Progressive ratio test 1 active lever presses1.71.72.4-0.3-1.5-1.3-1.2-1.4-1.31.5-1.4-1.4-1.41.3
Progressive ratio test 1 breakpoint1.51.62.1-0.5-1.5-1.2-1.1-1.2-1.31.5-1.3-1.3-1.31.3
Progressive ratio test 1 inactive lever presses2.22.33.8-0.6-1.6-1.5-1.4-1.6-1.61.6-1.5-1.5-1.51.9
Progressive ratio test 2 active lever presses5.65.97.8-1.3-2.5-2.6-2.4-2.3-2.72.5-2.8-2.5-2.52.4
Progressive ratio test 2 breakpoint6.57.29.2-1.5-2.7-2.9-2.6-2.6-2.92.7-3.0-2.8-2.72.8
Progressive ratio test 2 inactive lever presses2.32.64.5-1.2-1.5-1.7-1.3-1.4-2.01.5-1.7-1.5-1.52.1
Total sessions with >9 infusions0.60.71.0-0.9-0.8-0.9-0.6-0.6-1.00.8-0.9-0.7-0.80.7
Short access day 1 total inactive lever presses1.01.13.3-1.8-0.7-0.6-0.6-0.4-1.70.7-1.0-0.7-0.71.4
Short access day 10 total inactive lever presses1.11.21.80.11.31.31.21.00.9-1.31.31.31.3-0.6
Short access day 1 total infusions0.00.00.10.1-0.2-0.20.1-0.0-0.30.2-0.2-0.1-0.20.0
Short access day 10 total infusions0.10.10.2-0.3-0.3-0.3-0.1-0.1-0.50.3-0.4-0.3-0.30.1
Short access total infusions0.91.01.4-0.4-1.2-1.2-0.8-1.0-1.01.2-1.0-1.1-1.11.1
Short access day 1 locomotion0.00.00.00.20.0-0.10.20.10.1-0.00.10.10.1-0.1
Short access day 10 total locomotion0.20.20.40.30.50.40.60.40.5-0.50.60.50.50.1
Short access total locomotion0.30.30.5-0.10.60.50.70.60.3-0.60.50.60.6-0.1
Compulsive drug intake1.01.01.40.0-1.1-1.0-1.0-1.2-0.61.1-1.0-1.2-1.10.9
One hour access (0.3 mA shock)9.911.513.5-1.9-3.5-3.7-3.3-3.4-3.43.5-3.7-3.5-3.53.4
One hour access (shock baseline)2.73.13.9-1.4-1.7-1.9-1.7-1.7-2.01.7-1.9-1.7-1.71.8
Number of responses in last shaping day2.32.33.8-1.6-1.4-1.6-1.4-1.2-1.91.4-1.8-1.5-1.51.4
Context. condit. distance diff. score1.92.44.20.2-1.7-1.7-1.7-2.0-0.61.7-1.2-1.8-1.71.6
Locomotion velocity, session 13.23.56.2-1.21.92.22.32.50.5-1.91.42.02.0-1.7
Locomotion distance, session 10.20.30.6-0.10.50.60.80.70.2-0.50.50.60.5-0.3
Locomotion velocity, session 20.80.91.5-0.20.91.21.21.20.4-0.90.81.01.0-1.1
Locomotion distance, session 20.30.41.11.10.30.60.60.40.9-0.30.70.50.4-0.7
Locomotion velocity, session 30.20.20.30.5-0.4-0.5-0.6-0.5-0.20.4-0.5-0.5-0.50.2
Locomotion distance, session 30.90.91.71.2-1.0-1.0-1.1-1.30.11.0-0.7-1.1-1.10.4
Stereotopy head waving bouts, day 30.20.21.4-1.20.20.20.20.7-0.7-0.2-0.20.30.3-0.2
Stereotopy head waving duration, day 30.20.21.2-1.10.30.20.30.6-0.4-0.30.10.50.40.1
Locomotion velocity, session 70.50.51.60.9-0.5-0.7-0.6-1.30.60.50.0-0.7-0.61.0
Locomotion distance, session 70.60.72.00.9-0.7-0.8-0.8-1.40.20.7-0.3-0.9-0.81.1
Stereotopy head waving bouts, day 70.10.10.7-0.80.20.10.10.5-0.4-0.2-0.20.10.2-0.5
Stereotopy head waving duration, day 70.40.52.9-1.7-0.2-0.3-0.20.5-1.10.2-0.9-0.2-0.2-0.4
Locomotion velocity, session 80.30.30.6-0.3-0.6-0.5-0.5-0.8-0.40.6-0.5-0.7-0.70.7
Locomotion distance, session 80.30.51.31.0-0.6-0.6-0.5-1.20.50.6-0.1-0.7-0.70.8
Degree of sensitization distance0.40.40.90.50.60.50.60.10.9-0.61.00.60.60.2
Degree of sensitization stereotypy0.30.31.0-1.0-0.3-0.4-0.40.1-0.90.3-0.8-0.4-0.4-0.2
Condit. Reinf. active minus inactive responses0.80.91.60.90.90.90.80.91.3-0.91.10.90.9-1.3
Condit. Reinf. active-inactive response ratio0.91.01.8-0.31.10.90.91.40.5-1.10.71.11.1-1.3
Condit. Reinf. active responses0.20.21.11.0-0.1-0.0-0.1-0.30.90.10.4-0.1-0.1-0.3
Condit. Reinf. inactive responses0.70.81.80.8-1.0-0.8-0.9-1.30.11.0-0.5-1.0-1.01.0
Incentive salience index mean1.21.53.41.70.90.90.90.71.8-0.91.41.01.0-1.5
Condit. Reinf. lever presses1.62.14.21.91.21.21.20.92.0-1.21.71.31.3-1.6
Time in familiar zone, hab. session 10.20.21.2-1.1-0.1-0.1-0.00.1-0.70.1-0.4-0.1-0.10.3
Time in novel zone, hab. session 10.70.71.51.20.70.60.70.51.0-0.70.90.70.7-0.8
Total zone transitions, hab. session 10.00.00.1-0.0-0.2-0.2-0.0-0.0-0.20.2-0.1-0.1-0.10.3
Total locomotion distance, hab. session 10.81.21.81.21.11.11.10.81.3-1.11.31.11.1-0.7
Locomotion velocity, hab. session 11.21.82.81.51.31.31.30.91.7-1.31.71.31.3-0.9
Time in familiar zone, hab. session 20.30.30.7-0.50.50.60.60.8-0.2-0.50.20.50.5-0.4
Time in novel zone, hab. session 20.00.00.10.1-0.2-0.3-0.3-0.2-0.20.2-0.2-0.2-0.20.1
Total zone transitions, hab. session 20.30.31.0-0.50.50.50.61.00.0-0.50.20.60.5-0.9
Total locomotion distance, hab. session 20.50.60.90.20.90.80.91.00.6-0.90.70.80.8-0.9
Locomotion velocity, hab. session 20.60.81.00.61.00.91.00.81.0-1.01.00.90.9-0.9
Novel to familiar place preference ratio0.40.41.50.5-0.4-0.6-0.7-1.0-0.20.4-0.2-0.5-0.51.2
Novelty place preference0.50.51.80.4-0.5-0.6-0.7-1.1-0.30.5-0.3-0.6-0.61.3
Time in novel zone, NPP test0.30.31.20.5-0.4-0.5-0.6-0.9-0.20.4-0.1-0.5-0.41.1
Total zone transitions, NPP test0.60.81.40.60.80.81.10.81.1-0.81.00.80.8-1.2
Total locomotion distance, NPP test1.82.53.51.31.51.71.81.31.9-1.51.91.61.5-1.5
Locomotion velocity, NPP test1.72.44.01.61.41.61.71.12.0-1.41.91.51.4-1.4
Pavlov. Cond. lever latency0.91.13.9-2.0-0.7-0.6-0.50.0-1.90.7-1.3-0.6-0.60.6
Pavlov. Cond. magazine entry latency0.91.22.60.90.91.10.91.01.4-0.91.10.90.9-1.6
Pavlov. Cond. change in total contacts1.01.12.90.80.90.90.81.11.2-0.90.91.00.9-1.7
Pavlov. Cond. index score0.81.03.51.80.60.70.50.21.9-0.61.20.60.6-1.1
Pavlov. Cond. latency score1.01.24.92.20.50.60.4-0.02.1-0.51.30.50.5-0.9
Pavlov. Cond. lever contacts1.11.34.52.10.70.70.60.22.0-0.71.40.70.7-0.9
Pavlov. Cond. magazine entry number0.20.31.1-0.2-0.4-0.5-0.3-0.5-0.60.4-0.4-0.4-0.41.0
Pavlov. Cond. intertrial magazine entries0.40.50.90.8-0.8-0.7-0.6-1.0-0.10.8-0.4-0.7-0.80.7
Pavlov. Cond. lever-magazine prob. diff.1.21.44.21.90.80.90.80.52.1-0.81.40.80.8-1.3
Pavlov. Cond. response bias0.91.12.40.70.91.10.81.01.3-0.91.00.90.9-1.5
Bone: apparent density7.812.916.3-3.2-3.6-3.3-3.4-3.2-3.93.6-3.8-3.6-3.64.0
Bone surface4.57.911.6-2.9-2.8-2.5-2.7-2.1-3.42.8-3.3-2.8-2.82.7
Bone volume5.89.711.5-2.6-3.3-2.8-3.1-2.8-3.33.3-3.4-3.2-3.33.2
Bone: connectivity density4.57.110.5-3.1-2.5-2.3-2.4-2.1-3.22.5-2.9-2.5-2.53.1
Bone: cortical apparent density2.02.63.40.21.81.71.71.81.1-1.81.61.81.8-1.4
Bone: cortical area3.55.37.2-0.5-2.6-2.5-2.5-2.5-1.62.6-2.5-2.7-2.71.7
Bone: cortical porosity0.20.20.30.30.50.40.50.20.6-0.50.60.40.5-0.3
Bone: cortical porosity0.00.00.00.0-0.0-0.10.0-0.20.10.00.0-0.1-0.10.0
Bone: cortical thickness0.20.40.70.1-0.8-0.6-0.7-0.80.10.8-0.5-0.8-0.80.1
Bone: cortical thickness0.50.61.20.70.80.70.80.51.1-0.81.00.70.7-0.7
Bone: cortical tissue density2.02.63.50.21.81.81.71.91.1-1.81.61.81.8-1.4
Bone: elastic displacement2.83.25.3-0.52.12.02.02.30.7-2.11.62.12.1-1.2
Bone: elastic work1.41.83.0-0.81.51.61.51.70.2-1.51.21.61.6-0.6
Bone: endosteal estimation5.110.914.0-1.7-3.4-3.4-3.5-3.0-3.53.4-3.7-3.5-3.53.2
Bone: endosteal perimeter5.511.414.4-1.8-3.5-3.5-3.5-3.1-3.63.5-3.8-3.6-3.53.4
Bone: final force1.22.02.7-0.6-1.6-1.5-1.6-1.2-1.31.6-1.7-1.6-1.60.9
Bone: final moment1.22.03.1-0.9-1.5-1.4-1.5-1.0-1.51.5-1.8-1.5-1.50.9
Bone: marrow area5.311.414.6-1.8-3.5-3.5-3.5-3.1-3.63.5-3.8-3.6-3.53.3
Bone: maximum diameter9.116.819.6-1.9-4.3-4.4-4.3-4.0-3.94.3-4.4-4.4-4.44.0
Bone: maximum force2.95.07.0-1.4-2.4-2.3-2.4-1.9-2.32.4-2.6-2.4-2.41.8
Bone: maximum moment2.84.87.4-1.7-2.3-2.2-2.3-1.6-2.62.3-2.7-2.3-2.31.7
Bone: minimum diameter9.016.620.5-1.6-4.5-4.4-4.4-4.0-3.64.5-4.5-4.5-4.53.2
Bone: periosteal estimation6.212.815.8-1.8-3.8-3.7-3.8-3.4-3.43.8-4.0-3.9-3.93.3
Bone: periosteal perimeter5.69.311.4-0.9-3.3-3.2-3.3-3.2-2.63.3-3.2-3.4-3.32.9
Bone: post-yield work3.85.27.2-1.0-2.5-2.6-2.6-2.1-2.12.5-2.7-2.5-2.51.3
Bone: stiffness3.25.07.10.1-2.5-2.7-2.6-2.5-1.42.5-2.3-2.5-2.51.8
Bone: tissue strength0.30.31.2-1.10.0-0.10.10.8-0.8-0.0-0.40.20.1-0.4
Bone: trabecular number6.19.512.7-3.2-3.1-2.7-2.9-2.5-3.63.1-3.3-3.0-3.03.3
Bone: trabecular spacing2.53.24.91.81.71.51.61.52.2-1.71.91.71.7-2.1
Bone: trabecular thickness5.16.27.3-2.4-2.6-2.1-2.4-2.2-2.72.6-2.7-2.6-2.62.5
Bone: trabecular tissue density1.11.53.4-0.2-1.3-1.3-1.2-1.4-0.91.3-1.0-1.2-1.21.8
Breakpoint value in progressive ratio session0.70.71.70.5-0.9-0.8-1.0-1.3-0.00.9-0.4-0.9-0.91.0
Distance traveled before self-admin0.40.41.61.30.50.50.50.21.0-0.50.70.50.5-0.5
Distance traveled after self-admin0.20.21.0-1.0-0.0-0.00.10.1-0.40.00.10.30.10.8
Delta time in closed arm before/after self-admin0.40.41.41.10.40.10.40.40.8-0.40.40.40.4-1.2
Delta time in open arm before/after self-admin0.10.10.4-0.10.30.40.4-0.00.5-0.30.60.40.40.3
Diff in mean of infusions in LGA sessions0.30.31.51.2-0.6-0.4-0.6-0.60.20.6-0.2-0.4-0.50.3
Extinction: sum of active levers before priming0.30.30.60.4-0.8-0.5-0.7-0.7-0.10.8-0.5-0.6-0.70.1
Active lever presses in extinction session 60.80.82.10.4-0.9-1.1-0.8-1.40.00.9-0.3-0.7-0.81.4
Delta distance traveled before/after self-admin1.21.32.5-1.6-1.1-0.9-0.9-0.8-1.31.1-1.0-0.9-1.01.6
Delta ambulatory time before/after self-admin2.12.33.8-1.6-1.6-1.4-1.4-1.3-1.61.6-1.4-1.3-1.41.9
Time in closed arm before self-admin0.30.40.80.40.60.60.60.40.6-0.60.90.70.70.3
Time in closed arm after self-admin1.61.74.82.20.90.81.00.52.0-0.91.71.11.0-1.0
Time in open arm before self-admin0.10.10.4-0.6-0.00.10.10.3-0.50.0-0.30.0-0.0-0.3
Time in open arm after self-admin0.70.72.2-1.5-0.6-0.6-0.6-0.6-1.10.6-0.8-0.6-0.61.1
Sum of active levers in priming session hrs 5-60.60.61.0-0.90.80.80.71.0-0.0-0.80.50.90.8-0.0
Time to tail flick, vehicle, before self-admin1.01.01.6-0.61.11.21.31.10.4-1.11.01.11.1-0.3
Time to tail flick, vehicle, after self-admin0.80.83.11.8-0.6-0.6-0.6-1.50.80.60.1-0.7-0.60.8
Time to tail flick, test, before self-admin1.91.94.30.2-1.5-1.2-1.3-2.1-0.41.5-0.9-1.6-1.51.5
Time to tail flick, test, after self-admin0.40.40.8-0.30.90.70.80.40.7-0.90.80.60.7-0.2
Delta time to tail flick, vehicle, before/after SA3.13.07.11.9-1.7-1.8-1.8-2.70.31.7-0.9-1.8-1.81.5
Delta time to tail flick, test, before/after SA0.20.20.4-0.10.70.30.40.50.3-0.70.40.50.6-0.3
Ambulatory time before self-admin1.11.11.71.11.01.00.90.81.3-1.01.21.11.1-1.0
Ambulatory time after self-admin0.20.21.0-0.9-0.2-0.1-0.1-0.2-0.30.20.10.1-0.01.0
Total heroin consumption0.91.11.70.2-1.2-0.9-1.3-1.2-0.71.2-0.9-1.0-1.11.1
Area under the delay curve0.50.61.10.30.70.70.80.51.0-0.71.00.80.7-0.8
Delay disc. indifference point, 0s delay0.50.52.21.50.10.10.1-0.81.4-0.10.90.30.10.3
Delay disc. indifference point, 16s delay0.00.00.2-0.4-0.2-0.1-0.1-0.0-0.30.2-0.2-0.1-0.20.1
Delay disc. indifference point, 2s delay0.30.40.60.00.70.70.60.60.5-0.70.70.80.7-0.1
Delay disc. indifference point, 24s delay1.01.02.60.90.80.80.70.51.4-0.81.00.80.9-1.6
Delay disc. indifference point, 4s delay0.40.41.40.90.30.60.4-0.21.2-0.30.90.50.4-0.4
Delay disc. indifference point, 8s delay2.62.73.40.11.71.71.81.61.6-1.71.81.81.7-1.7
Delay discount exponential model param0.60.61.1-0.3-0.7-0.8-0.8-0.5-1.10.7-1.0-0.8-0.80.9
Delay discount hyperbolic model param0.60.71.0-0.3-0.8-0.8-0.8-0.6-1.00.8-1.0-0.9-0.80.9
Fecal boli incidents, locomotor time 10.10.10.30.30.0-0.10.1-0.60.6-0.00.40.10.10.3
Change in fecal boli incidents, locomotor task0.00.00.20.30.10.30.00.4-0.1-0.1-0.10.00.0-0.2
Time >=10cm from walls, locomotor time 13.73.76.21.1-2.2-1.9-2.3-2.5-0.72.2-1.8-2.3-2.21.3
Bouts of movement, locomotor time 10.40.40.9-0.5-0.4-0.9-0.6-0.8-0.40.4-0.5-0.6-0.50.9
Total resting periods, locomotor time 10.40.51.2-0.3-0.6-0.9-0.7-0.9-0.40.6-0.5-0.6-0.61.1
Rest time, locomotor task time 10.10.10.5-0.70.3-0.20.1-0.1-0.2-0.30.20.10.20.7
Distance moved, locomotor task time 10.40.52.71.60.10.50.10.10.9-0.10.30.20.1-1.1
Vertical activity count, locomotor time 10.10.10.40.4-0.60.0-0.3-0.0-0.10.6-0.4-0.3-0.4-0.3
Time >=10cm from walls, locomotor time 20.40.53.01.7-0.3-0.1-0.4-0.90.80.30.1-0.4-0.40.0
Bouts of movement, locomotor time 22.83.04.60.91.91.81.81.41.9-1.92.11.91.9-1.0
Total resting periods, locomotor time 22.83.04.71.01.91.71.81.32.0-1.92.21.91.9-1.1
Rest time, locomotor task time 20.10.10.30.40.2-0.30.1-0.40.6-0.20.40.10.20.1
Distance moved, locomotor task time 20.20.31.71.3-0.40.2-0.4-0.40.30.4-0.2-0.4-0.5-0.5
Vertical activity count, locomotor time 20.20.20.70.10.20.90.40.50.1-0.20.20.20.2-0.7
Weight adjusted by age0.30.41.0-1.00.70.50.60.40.2-0.70.70.60.60.4
Seeking ratio, delayed vs. immediate footshock0.10.10.30.5-0.1-0.3-0.1-0.50.20.1-0.0-0.2-0.20.1
Locomotion in novel chamber1.31.63.3-0.9-1.1-1.3-1.2-1.3-1.31.1-1.2-1.3-1.21.8
Locomotion in novel chamber post-restriction2.32.74.60.6-1.8-1.7-1.9-2.2-0.71.8-1.4-1.7-1.81.8
Progressive ratio0.50.51.50.6-0.8-0.8-0.7-1.20.10.8-0.4-0.7-0.80.5
Food seeking constrained by brief footshock3.13.74.9-0.2-2.2-2.2-2.1-2.1-1.52.2-2.2-2.2-2.21.1
Seeking ratio, punishment vs. effort0.10.10.3-0.2-0.2-0.2-0.30.1-0.60.2-0.5-0.4-0.3-0.3
Run reversals in cocaine runway, females0.50.50.9-1.00.70.80.70.9-0.0-0.70.50.70.70.2
Run reversals in cocaine runway, males0.10.10.50.20.10.0-0.00.10.2-0.10.00.10.1-0.7
Latency to leave start box in cocaine runway0.50.60.90.7-0.8-0.6-0.8-0.8-0.50.8-0.7-0.8-0.80.9
Latency to leave start box in cocaine runway, F0.10.20.70.8-0.3-0.4-0.3-0.3-0.20.3-0.3-0.2-0.30.5
Latency to leave start box in cocaine runway, M0.70.71.10.2-1.0-0.5-0.9-1.0-0.71.0-0.9-1.0-1.00.7
Cd content in liver0.20.20.5-0.50.30.20.20.7-0.3-0.3-0.20.20.2-0.7
Co content in liver1.01.12.9-1.71.01.01.11.6-0.4-1.00.41.11.0-0.6
Cu content in liver2.63.15.7-0.92.02.02.02.40.4-2.01.42.02.0-1.4
Fe content in liver3.94.66.20.82.42.42.22.41.7-2.42.02.12.2-2.5
K content in liver1.21.22.51.21.10.91.10.31.6-1.11.61.11.1-0.2
Mg content in liver1.91.92.81.01.51.41.51.11.5-1.51.71.51.5-1.1
Mn content in liver1.92.22.71.01.51.51.51.41.5-1.51.61.51.5-1.4
Na content in liver3.23.46.32.01.71.61.81.22.5-1.72.41.81.8-1.4
Rb content in liver0.10.11.01.0-0.1-0.2-0.2-0.50.30.10.1-0.2-0.20.2
Se content in liver22.527.236.91.15.65.55.66.14.0-5.65.05.65.6-5.7
Sr content in liver0.80.83.9-2.0-0.4-0.4-0.30.2-1.50.4-0.9-0.3-0.40.6
Zn content in liver10.311.313.11.83.63.63.53.33.3-3.63.63.53.5-3.4