Trub1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017321 0.17 0.09 0.0e+00 0.16 0.15 0.16 0.16 6.0e-17 3.6e-16 5.6e-17 2.2e-17
2 Adipose mRNA stability ENSRNOG00000017321 0.1 0.06 1.7e-08 0.05 0.04 0.05 0.05 5.3e-06 1.1e-05 1.6e-06 3.1e-06
3 BLA gene expression ENSRNOG00000017321 0.31 0.13 1.5e-10 0.21 0.2 0.2 0.21 2.9e-11 3.7e-11 4.6e-11 2.6e-11
4 BLA mRNA stability ENSRNOG00000017321 0.48 0.14 0.0e+00 0.29 0.29 0.27 0.31 6.4e-16 7.2e-16 6.8e-15 5.7e-17
5 Brain gene expression ENSRNOG00000017321 0.16 0.07 1.5e-14 0.07 0.16 0.16 0.16 1.7e-07 7.0e-15 1.3e-14 1.1e-14
6 Brain intron excision ratio chr1:256525787:256535147 0.05 0.04 4.3e-03 0.01 0.03 0.03 0.02 1.5e-02 9.3e-04 1.9e-03 3.4e-03
7 Brain intron excision ratio chr1:256535228:256547471 0.03 0.02 2.8e-03 0.03 0.02 0.01 0.02 1.1e-03 3.0e-03 3.5e-02 3.1e-03
8 Brain intron excision ratio chr1:256535228:256548812 0.04 0.03 9.9e-06 0.05 0.06 0.05 0.05 3.4e-05 3.5e-06 3.6e-05 1.1e-05
9 Brain intron excision ratio chr1:256547543:256548812 0.05 0.04 6.0e-04 0.04 0.02 0.02 0.03 6.9e-05 3.8e-03 5.3e-03 1.4e-03
10 Brain mRNA stability ENSRNOG00000017321 0.5 0.11 0.0e+00 0.44 0.48 0.47 0.47 4.1e-44 2.5e-49 4.5e-48 1.3e-48
11 IL gene expression ENSRNOG00000017321 0.32 0.14 1.1e-04 0.15 0.12 0.14 0.14 2.0e-04 9.8e-04 3.9e-04 3.4e-04
12 IL mRNA stability ENSRNOG00000017321 0.52 0.14 3.4e-10 0.26 0.33 0.38 0.33 6.9e-07 8.5e-09 5.8e-10 1.2e-08
13 LHb gene expression ENSRNOG00000017321 0.21 0.12 5.3e-03 0.05 0.09 0.07 0.04 3.1e-02 3.6e-03 7.5e-03 3.3e-02
14 LHb mRNA stability ENSRNOG00000017321 0.5 0.18 4.6e-08 0.34 0.36 0.34 0.37 6.7e-09 1.4e-09 5.3e-09 9.3e-10
15 Liver gene expression ENSRNOG00000017321 0.42 0.14 0.0e+00 0.43 0.44 0.44 0.44 1.8e-52 3.1e-53 3.9e-54 3.5e-54
16 NAcc gene expression ENSRNOG00000017321 0.14 0.08 4.9e-09 0.08 0.09 0.07 0.09 1.8e-06 1.7e-07 1.0e-05 3.3e-07
17 NAcc mRNA stability ENSRNOG00000017321 0.35 0.14 0.0e+00 0.23 0.24 0.24 0.24 2.2e-17 7.6e-18 1.2e-17 1.1e-17
18 OFC gene expression ENSRNOG00000017321 0.19 0.12 9.7e-03 0.11 0.08 0.11 0.09 1.7e-03 6.2e-03 1.2e-03 3.8e-03
19 OFC mRNA stability ENSRNOG00000017321 0.58 0.18 1.7e-08 0.17 0.32 0.31 0.27 8.7e-05 3.0e-08 4.9e-08 3.7e-07
20 PL gene expression ENSRNOG00000017321 0.25 0.1 2.1e-14 0.18 0.19 0.17 0.18 8.7e-14 2.0e-14 2.5e-13 1.3e-13
21 PL mRNA stability ENSRNOG00000017321 0.47 0.12 0.0e+00 0.39 0.42 0.41 0.41 5.0e-31 1.4e-34 1.9e-33 1.3e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
BMI with tail3.110.137.0-3.4-1.62.82.60.04.3-3.34.8-3.33.22.42.8-0.33.9-6.1-1.62.02.63.92.63.0
BMI without tail1.73.511.5-1.5-0.32.01.90.32.6-1.52.6-1.62.01.41.80.12.3-3.4-0.71.31.92.31.82.0
Body weight2.912.246.9-3.6-1.82.92.8-0.04.6-3.55.2-3.53.52.83.0-0.34.4-6.9-1.62.22.84.42.93.4
Epididymis fat weight4.09.331.8-2.4-1.03.02.90.53.8-2.23.8-2.23.33.03.00.44.2-5.6-0.62.52.84.13.13.4
Glucose1.62.46.9-1.6-0.91.31.30.22.1-1.42.1-1.51.81.41.60.02.0-2.6-0.71.11.32.21.11.3
Heart weight0.71.03.9-1.5-1.00.30.3-0.51.1-1.31.8-1.30.70.50.4-0.61.1-2.0-0.90.20.30.90.50.7
Left kidney weight2.67.413.7-3.2-3.7-2.6-2.7-3.6-1.2-3.02.5-3.0-2.1-2.5-2.4-3.5-1.6-2.1-3.5-2.8-2.8-1.6-2.6-2.4
Right kidney weight3.08.619.4-4.4-4.4-1.8-2.0-3.60.3-4.24.1-4.3-1.1-1.8-1.5-3.7-0.4-4.1-4.1-2.2-1.9-0.2-1.9-1.6
Tail length0.10.40.80.30.50.90.90.60.70.20.10.00.70.70.80.60.8-0.40.40.70.90.80.70.7
Length with tail0.41.46.2-1.1-0.80.80.8-0.21.4-1.11.7-1.21.11.11.0-0.21.7-2.5-0.50.80.81.61.01.1
Length without tail0.91.99.0-1.7-1.40.70.6-0.41.4-1.62.1-1.51.21.21.0-0.41.9-3.0-0.80.90.61.80.91.1
Liver weight, left1.42.36.6-1.1-0.41.51.40.32.2-1.22.1-1.41.71.41.50.12.0-2.6-0.51.11.41.91.51.7
Liver weight, right2.13.413.7-2.1-1.21.41.3-0.22.5-2.13.0-2.01.81.41.4-0.42.2-3.7-1.11.01.32.11.51.7
Parametrial fat weight5.610.921.9-1.50.23.63.61.74.7-1.43.3-1.54.23.53.81.44.4-4.60.23.33.64.63.63.9
Retroperitoneal fat weight4.314.251.4-3.6-1.63.23.10.35.0-3.45.3-3.44.03.53.30.05.0-7.2-1.32.83.14.83.64.0
Intraocular pressure2.02.96.1-0.8-0.11.91.90.92.1-0.81.6-0.72.12.11.90.82.5-2.10.31.71.92.42.02.1
Extensor digitorum longus weight0.62.54.9-0.40.41.81.81.12.2-0.51.1-0.52.11.91.91.02.1-1.90.41.71.82.11.81.9
Soleus weight1.54.318.6-3.0-2.5-0.0-0.1-1.91.7-3.33.8-3.30.5-0.2-0.0-2.10.9-4.3-2.7-0.6-0.11.0-0.00.3
Tibialis anterior weight0.51.63.3-0.50.11.41.40.81.8-0.71.0-0.61.71.51.60.71.6-1.60.21.31.41.71.21.3
Tibia length0.41.23.7-1.9-1.7-0.3-0.3-1.30.4-1.71.9-1.7-0.1-0.3-0.3-1.30.3-1.7-1.5-0.5-0.40.3-0.2-0.1
Number of licking bursts1.11.31.81.01.31.31.31.30.81.0-0.40.91.11.21.21.31.10.01.21.31.31.01.31.3
Food consumed during 24 hour testing period0.70.82.61.51.1-0.2-0.10.5-1.11.5-1.61.6-0.6-0.3-0.20.6-0.71.51.0-0.1-0.1-0.6-0.2-0.4
Times rat made contact with spout0.30.30.5-0.4-0.5-0.6-0.6-0.7-0.5-0.30.2-0.3-0.7-0.7-0.7-0.6-0.6-0.1-0.5-0.6-0.6-0.5-0.5-0.5
Mean time between licks in bursts0.71.02.21.51.30.80.81.1-0.11.5-1.21.50.50.90.81.30.60.51.51.00.80.50.90.7
Mean num. licks in bursts2.12.63.7-1.4-1.9-1.8-1.8-1.9-1.2-1.40.7-1.2-1.6-1.8-1.7-1.9-1.5-0.3-1.7-1.8-1.8-1.4-1.8-1.8
Std. dev. time between licks in bursts0.60.72.11.41.00.30.30.7-0.61.5-1.31.4-0.00.50.20.90.20.81.30.60.30.00.50.4
Water consumed over 24 hours0.50.51.0-0.2-0.5-0.8-0.8-0.9-0.8-0.20.1-0.2-0.9-1.0-0.9-0.8-0.90.1-0.7-0.9-0.8-0.8-0.9-0.9
Indifference point 0 sec2.03.29.3-1.9-0.81.61.50.22.5-1.82.5-1.62.01.41.70.02.3-3.0-0.71.31.62.31.51.7
Indifference point AUC1.11.33.6-1.0-0.31.21.20.51.9-1.01.4-1.11.61.01.40.31.4-1.5-0.30.91.11.60.91.1
Indifference point function ln k0.30.41.20.60.0-0.6-0.6-0.4-1.10.6-0.70.6-0.9-0.6-0.7-0.2-0.70.70.1-0.5-0.6-0.7-0.6-0.7
Indifference point function log k0.30.41.20.60.0-0.6-0.6-0.4-1.10.6-0.70.6-0.9-0.6-0.7-0.2-0.70.70.1-0.5-0.6-0.7-0.6-0.7
Delay discounting total patch changes 0 sec2.23.69.6-1.9-0.71.81.70.42.7-1.92.6-1.72.21.61.90.12.5-3.1-0.71.41.72.51.61.9
Delay discounting total patch changes 12 sec1.92.56.0-1.00.21.71.70.92.5-1.01.7-1.02.11.61.80.62.1-2.1-0.01.51.72.11.71.8
Delay discounting total patch changes 18 sec3.95.211.9-1.5-0.12.52.41.23.4-1.62.4-1.53.02.32.80.93.0-2.9-0.22.12.43.22.22.4
Delay discounting total patch changes 24 sec3.84.811.4-1.50.02.32.31.23.4-1.42.3-1.42.92.32.50.82.9-2.7-0.12.12.32.92.32.5
Delay discounting total patch changes 6 sec3.55.312.6-1.9-0.62.32.20.73.4-1.92.8-1.92.82.22.50.43.1-3.5-0.61.92.23.22.02.3
Delay discounting time to switch 0 sec0.20.30.80.60.5-0.6-0.5-0.0-0.70.6-0.70.6-0.6-0.3-0.70.0-0.70.70.3-0.3-0.6-0.9-0.2-0.3
Delay discounting water rate 0 sec0.30.51.1-0.9-0.60.70.60.01.0-0.91.0-0.80.80.50.8-0.11.0-1.0-0.40.40.61.00.40.5
Delay discounting water rate 12 sec1.82.75.3-0.20.62.02.01.32.1-0.10.9-0.12.11.92.01.22.3-1.50.71.82.02.31.92.0
Delay discounting water rate 18 sec0.40.51.6-1.2-1.2-0.3-0.4-0.70.2-1.21.0-1.0-0.1-0.2-0.2-0.80.2-1.0-0.9-0.4-0.30.1-0.3-0.3
Delay discounting water rate 24 sec0.40.62.0-1.4-1.1-0.0-0.1-0.70.6-1.31.3-1.20.1-0.20.0-0.80.3-1.3-1.1-0.3-0.10.3-0.2-0.1
Delay discounting water rate 6 sec0.50.82.5-1.5-1.3-0.1-0.2-0.70.7-1.61.4-1.50.2-0.30.0-0.90.2-1.1-1.2-0.4-0.20.3-0.4-0.2
Locomotor activity0.40.72.2-1.5-1.3-0.2-0.3-0.80.4-1.41.3-1.30.1-0.2-0.1-0.90.3-1.4-1.1-0.3-0.30.3-0.3-0.2
Locomotor testing distance1.22.04.4-2.1-2.1-1.0-1.1-1.7-0.0-2.01.8-2.0-0.6-1.1-0.9-1.8-0.4-1.5-2.0-1.2-1.0-0.3-1.2-1.0
Locomotor testing rearing0.81.23.4-1.7-1.5-0.6-0.7-1.10.6-1.81.6-1.8-0.1-0.7-0.3-1.3-0.2-1.3-1.7-0.8-0.6-0.0-0.8-0.6
Light reinforcement 10.40.83.51.00.7-0.5-0.50.3-1.10.9-1.51.2-0.8-0.7-0.60.3-1.11.90.6-0.4-0.5-1.1-0.6-0.7
Light reinforcement 21.21.63.70.90.2-1.3-1.2-0.4-1.81.0-1.61.0-1.5-1.2-1.3-0.2-1.81.90.3-1.1-1.2-1.7-1.2-1.4
Reaction time number correct0.71.02.5-1.2-0.50.80.80.11.6-1.21.5-1.21.10.60.9-0.11.0-1.6-0.60.50.81.10.70.8
Reaction time mean minus median0.40.51.7-1.2-1.0-0.1-0.1-0.50.8-1.21.3-1.20.40.20.1-0.60.4-1.2-0.9-0.1-0.10.4-0.00.1
Reaction time mean minus median AUC1.11.43.5-1.9-1.7-0.9-0.9-1.30.5-1.81.8-1.9-0.2-0.6-0.6-1.5-0.3-1.3-1.7-0.9-0.9-0.2-0.8-0.6
Reaction time num false alarms0.10.10.5-0.0-0.0-0.2-0.3-0.3-0.70.2-0.30.3-0.6-0.5-0.4-0.2-0.30.00.0-0.4-0.2-0.5-0.2-0.2
Reaction time num false alarms AUC0.20.30.8-0.4-0.5-0.5-0.6-0.7-0.8-0.2-0.0-0.1-0.9-0.8-0.7-0.6-0.6-0.0-0.4-0.7-0.5-0.7-0.5-0.5
Reaction time trials correct on left0.71.02.5-1.2-0.50.80.80.11.6-1.21.5-1.21.10.60.9-0.11.0-1.6-0.60.50.81.10.70.8
Reaction time trials on left0.71.12.8-1.3-0.50.80.80.11.7-1.21.6-1.31.10.70.9-0.21.1-1.7-0.70.50.91.10.70.9
Reaction time mean0.30.41.1-1.0-0.9-0.3-0.3-0.60.4-1.01.0-1.00.10.1-0.1-0.70.2-1.0-0.8-0.2-0.40.1-0.10.0
Reaction time mean AUC0.20.31.0-1.0-0.8-0.4-0.4-0.60.3-1.00.9-1.00.0-0.1-0.2-0.70.0-0.7-0.8-0.3-0.4-0.0-0.2-0.1
Median of all reaction times0.30.41.0-1.0-0.9-0.5-0.5-0.80.1-1.00.9-1.0-0.2-0.2-0.4-0.8-0.0-0.8-0.8-0.4-0.6-0.1-0.3-0.2
Reaction time omissions0.40.51.7-0.9-0.40.50.50.11.0-0.91.0-0.70.80.70.6-0.00.8-1.3-0.30.50.50.80.60.7
Reaction time false alarm rate0.40.62.20.60.2-0.6-0.6-0.3-1.50.8-1.11.0-1.1-0.7-0.9-0.1-0.80.90.4-0.5-0.6-1.0-0.4-0.6
Reaction time premature initiation rate1.21.62.7-1.1-1.5-1.3-1.4-1.6-0.9-1.00.8-0.9-1.2-1.3-1.4-1.6-1.1-0.5-1.5-1.4-1.4-1.0-1.3-1.2
Reaction time premature initiations1.31.83.9-1.9-1.9-0.9-1.0-1.60.1-1.91.8-1.8-0.6-1.0-0.9-1.7-0.5-1.5-2.0-1.2-1.0-0.3-1.0-0.8
Std. dev. reaction times0.81.14.0-1.7-1.30.10.1-0.61.2-1.61.9-1.60.70.40.4-0.80.9-2.0-1.10.10.00.80.20.4
Reaction time trials completed0.71.12.8-1.3-0.50.80.80.11.7-1.21.6-1.31.10.70.9-0.21.1-1.7-0.70.50.91.10.70.9
Reaction time trials AUC0.71.13.0-1.2-0.50.80.80.11.6-1.21.6-1.31.10.60.9-0.21.1-1.7-0.70.50.91.20.70.8
Social response proportion1.71.83.9-1.8-2.0-1.4-1.4-1.8-0.7-1.61.2-1.5-1.1-1.0-1.3-1.7-0.6-1.2-1.5-1.3-1.4-0.8-1.0-1.0
Social responses1.72.27.4-2.1-1.20.90.9-0.31.9-1.92.4-1.81.41.01.0-0.41.8-2.7-1.00.70.91.71.01.2
Social time1.01.33.8-2.0-1.7-0.7-0.7-1.30.2-1.81.7-1.7-0.3-0.5-0.6-1.40.0-1.6-1.5-0.8-0.7-0.1-0.5-0.3
Conditioned locomotion0.20.30.5-0.5-0.7-0.7-0.6-0.5-0.1-0.70.3-0.7-0.3-0.5-0.4-0.6-0.40.1-0.7-0.5-0.7-0.4-0.7-0.6
Cocaine response after cond. corrected3.13.55.6-0.5-1.2-2.4-2.4-1.8-2.0-0.4-0.4-0.4-2.3-2.3-2.3-1.7-2.41.2-1.3-2.2-2.3-2.3-2.3-2.3
Cocaine response after cond. not corrected2.52.74.8-0.2-0.9-2.1-2.1-1.3-1.9-0.1-0.8-0.0-2.0-2.0-2.0-1.3-2.21.5-0.8-1.9-2.1-2.1-2.0-2.1
Cocaine response before conditioning1.01.22.21.01.31.21.21.50.71.0-0.91.01.11.11.31.40.90.61.31.31.21.01.00.9
Saline control response0.60.81.9-1.2-1.4-0.9-0.9-0.9-0.3-1.30.5-1.1-0.5-0.8-0.6-1.0-0.6-0.0-1.0-0.8-0.9-0.4-1.1-1.0
Condit. Reinf. active minus inactive responses3.13.86.60.71.22.52.51.82.10.60.40.42.42.32.51.82.5-1.01.22.32.52.62.22.3
Condit. Reinf. active-inactive response ratio1.61.62.80.30.71.61.61.21.60.20.40.01.71.51.71.11.6-0.60.71.41.61.71.41.5
Condit. Reinf. active responses3.54.88.60.31.12.82.81.82.60.21.00.12.72.62.71.72.9-1.71.12.52.82.92.62.7
Condit. Reinf. inactive responses1.01.22.30.10.51.51.40.81.2-0.00.60.11.31.31.30.81.5-1.10.51.21.41.51.41.4
Condit. Reinf. lever presses1.01.42.40.10.71.51.51.01.5-0.00.6-0.01.51.41.50.91.5-0.90.51.31.51.51.41.4
Condit. Reinf. lever reinforcers received2.53.66.40.41.02.42.41.62.20.30.70.22.32.32.41.52.5-1.31.02.22.42.52.22.3
Pavlov. Cond. lever latency0.81.21.8-0.3-0.7-1.3-1.3-1.0-1.1-0.2-0.2-0.3-1.3-1.3-1.3-1.0-1.30.6-0.8-1.3-1.3-1.3-1.3-1.3
Pavlov. Cond. magazine entry latency0.50.61.1-0.00.40.90.90.61.0-0.10.5-0.10.90.90.80.50.9-0.80.30.80.90.81.01.0
Pavlov. Cond. change in total contacts1.01.42.9-0.10.31.41.41.01.6-0.30.7-0.31.61.41.60.81.6-1.00.41.31.41.71.21.3
Pavlov. Cond. index score0.71.01.9-0.10.31.21.20.71.3-0.30.7-0.31.31.21.20.61.4-1.10.31.11.21.41.11.2
Pavlov. Cond. latency score0.81.01.9-0.10.31.21.20.81.3-0.20.6-0.21.31.21.30.71.4-1.00.31.11.21.41.11.2
Pavlov. Cond. lever contacts0.40.50.9-0.20.20.90.90.50.9-0.30.5-0.20.90.80.90.51.0-0.70.20.80.81.00.80.8
Pavlov. Cond. magazine entry number0.40.51.10.1-0.3-0.8-0.8-0.6-1.00.3-0.50.2-0.9-0.9-0.8-0.5-0.90.8-0.3-0.8-0.8-0.8-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.30.20.50.50.30.7-0.20.5-0.30.50.30.40.10.4-0.5-0.10.30.50.40.40.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.4-0.30.11.00.90.51.1-0.40.7-0.41.11.01.00.41.2-1.10.10.90.91.20.91.0
Pavlov. Cond. response bias0.60.81.5-0.00.41.11.10.71.1-0.20.5-0.11.11.11.10.61.2-0.90.41.01.11.21.11.1
Conditioned reinforcement - actives2.52.53.8-0.8-1.5-1.9-1.9-1.8-1.6-0.80.2-0.9-1.8-1.9-1.8-1.7-1.80.3-1.4-1.9-1.9-1.6-2.0-1.9
Conditioned reinforcement - inactives0.10.10.4-0.6-0.6-0.2-0.2-0.40.0-0.50.5-0.4-0.1-0.2-0.2-0.4-0.0-0.6-0.4-0.2-0.2-0.0-0.2-0.1
Conditioned locomotion1.31.62.6-0.4-1.0-1.5-1.5-1.3-1.6-0.4-0.3-0.4-1.6-1.5-1.5-1.2-1.50.6-0.8-1.5-1.5-1.4-1.5-1.6
Intermittent access intake day 1-15 change1.00.92.9-1.3-0.60.60.5-0.01.5-1.21.6-1.21.10.70.7-0.21.0-1.7-0.60.50.51.10.70.9
Intermittent access intake escalation1.41.44.2-2.0-1.6-0.5-0.5-1.20.8-1.92.0-1.90.1-0.4-0.3-1.30.1-1.8-1.7-0.6-0.50.2-0.3-0.1
Intermittent access intake escalation 21.01.01.9-1.4-1.3-0.9-0.9-1.20.1-1.31.3-1.3-0.4-0.7-0.7-1.3-0.4-1.1-1.4-0.9-0.9-0.4-0.7-0.6
Intermitt. access day 1 inactive lever presses2.12.25.2-0.80.21.51.50.92.3-0.81.4-0.82.01.71.70.71.9-1.90.11.51.52.01.71.8
Intermitt. access day 15 inactive lever presses0.30.41.1-1.0-0.6-0.00.0-0.11.0-1.01.0-1.00.70.30.3-0.30.4-0.7-0.60.2-0.00.50.10.2
Intermitt. access escalation Index0.40.40.70.1-0.2-0.7-0.7-0.5-0.80.1-0.40.1-0.8-0.7-0.8-0.4-0.90.5-0.2-0.7-0.7-0.8-0.7-0.7
Intermittent access day 1 total infusions0.20.20.5-0.7-0.6-0.3-0.3-0.5-0.0-0.70.5-0.6-0.3-0.4-0.4-0.6-0.3-0.4-0.6-0.4-0.3-0.2-0.3-0.3
Intermittent access day 15 total infusions1.11.23.1-1.7-1.4-0.7-0.7-1.20.4-1.81.6-1.7-0.3-0.8-0.7-1.3-0.4-1.2-1.6-0.9-0.7-0.3-0.6-0.5
Intermittent access terminal intake (last 3 days)0.70.71.9-1.4-1.1-0.6-0.6-0.90.3-1.41.2-1.3-0.2-0.6-0.5-1.0-0.3-0.9-1.2-0.7-0.6-0.3-0.5-0.3
Intermittent access total infusions1.31.43.6-1.9-1.7-0.8-0.9-1.40.3-1.91.7-1.8-0.4-0.9-0.8-1.5-0.4-1.3-1.7-1.0-0.9-0.3-0.8-0.6
Intermittent access day 1 locomotion1.41.52.3-1.3-1.4-1.2-1.2-1.4-0.4-1.51.0-1.4-1.0-1.3-1.2-1.5-1.1-0.3-1.5-1.4-1.2-1.0-1.2-1.1
Intermittent access day 15 total locomotion1.51.65.0-1.7-1.00.60.6-0.21.9-1.82.2-1.81.20.50.8-0.51.1-2.1-1.10.40.61.30.70.9
Intermittent access total locomotion2.42.75.4-2.3-2.2-1.4-1.4-1.9-0.0-2.31.9-2.2-0.9-1.5-1.3-2.1-0.9-1.1-2.3-1.6-1.4-0.8-1.3-1.2
Intermittent access standard deviation0.60.61.7-0.50.00.70.70.41.3-0.61.0-0.61.00.80.80.21.0-1.2-0.10.70.70.90.80.9
Cocaine induced anxiety3.13.59.91.60.5-1.8-1.7-0.5-2.71.6-2.51.5-2.2-1.8-1.8-0.3-2.53.20.5-1.5-1.7-2.4-1.9-2.1
Post-drug Anxiety0.80.92.80.80.2-0.9-0.9-0.2-1.30.8-1.20.7-1.1-0.8-0.9-0.1-1.21.70.2-0.7-0.9-1.2-1.0-1.0
Baseline Anxiety3.53.77.9-1.3-0.22.01.90.82.7-1.32.2-1.32.42.02.00.62.6-2.8-0.21.71.92.62.12.3
Lifetime Intake1.31.53.5-1.8-1.7-0.9-0.9-1.40.2-1.91.6-1.7-0.4-0.9-0.8-1.5-0.4-1.3-1.7-1.0-1.0-0.3-0.8-0.7
Incentive Sensitization - Responses1.61.65.6-2.1-1.40.10.1-0.71.6-2.12.4-2.10.80.10.2-1.00.7-2.2-1.5-0.10.10.80.20.5
Incentive Sensitization - Breakpoint1.61.65.5-2.0-1.20.30.2-0.61.7-2.02.3-2.00.90.30.4-0.80.8-2.2-1.40.10.20.90.40.6
Progressive ratio test 1 active lever presses1.11.22.0-1.3-1.4-1.0-1.0-1.3-0.3-1.41.0-1.3-0.8-1.2-1.0-1.4-0.8-0.5-1.4-1.2-1.0-0.7-1.0-0.9
Progressive ratio test 1 breakpoint0.50.51.1-1.0-1.0-0.6-0.6-0.8-0.2-1.00.7-0.9-0.5-0.8-0.6-0.9-0.5-0.3-0.9-0.8-0.6-0.4-0.6-0.6
Progressive ratio test 1 inactive lever presses0.20.20.5-0.1-0.3-0.6-0.6-0.4-0.5-0.1-0.20.0-0.6-0.6-0.6-0.4-0.60.5-0.2-0.5-0.6-0.7-0.5-0.6
Progressive ratio test 2 active lever presses2.42.57.5-2.6-2.2-0.7-0.7-1.51.1-2.72.7-2.60.1-0.8-0.5-1.8-0.0-2.2-2.3-0.9-0.70.1-0.6-0.3
Progressive ratio test 2 breakpoint2.22.47.3-2.6-2.1-0.6-0.6-1.41.2-2.72.7-2.60.2-0.6-0.4-1.70.1-2.1-2.2-0.8-0.60.2-0.4-0.2
Progressive ratio test 2 inactive lever presses0.50.51.6-1.1-0.60.30.3-0.11.1-1.11.2-1.00.80.40.5-0.30.7-1.3-0.60.30.30.80.40.5
Total sessions with >9 infusions3.13.47.6-2.6-2.8-1.3-1.3-2.30.1-2.62.5-2.6-0.7-1.4-1.1-2.3-0.4-2.4-2.6-1.4-1.3-0.2-1.2-1.0
Short access day 1 total inactive lever presses0.20.20.70.60.3-0.3-0.30.0-0.80.6-0.80.7-0.5-0.2-0.40.2-0.50.70.4-0.2-0.3-0.5-0.2-0.3
Short access day 10 total inactive lever presses0.50.61.7-0.8-0.30.60.60.21.1-0.70.9-0.60.90.70.80.10.9-1.3-0.20.60.61.00.60.7
Short access day 1 total infusions1.41.52.4-1.1-1.4-1.4-1.4-1.6-0.8-1.10.8-1.0-1.2-1.3-1.4-1.5-1.1-0.5-1.4-1.4-1.4-1.1-1.3-1.2
Short access day 10 total infusions1.31.42.1-1.0-1.3-1.2-1.3-1.4-0.9-1.10.5-0.9-1.2-1.4-1.3-1.4-1.2-0.1-1.3-1.4-1.2-1.1-1.3-1.3
Short access total infusions1.31.52.6-1.4-1.6-1.3-1.3-1.5-0.5-1.41.0-1.3-0.9-1.2-1.2-1.5-0.9-0.7-1.5-1.3-1.3-0.8-1.2-1.1
Short access day 1 locomotion0.90.92.0-1.3-1.1-0.6-0.7-1.10.2-1.41.3-1.4-0.5-0.9-0.7-1.2-0.5-1.0-1.4-0.9-0.7-0.4-0.6-0.5
Short access day 10 total locomotion0.50.61.6-1.2-1.0-0.4-0.4-0.80.3-1.21.2-1.3-0.2-0.5-0.4-1.0-0.2-0.9-1.1-0.6-0.4-0.1-0.4-0.3
Short access total locomotion3.53.66.7-2.3-2.4-1.7-1.7-2.3-0.4-2.42.0-2.4-1.3-1.9-1.7-2.5-1.3-1.3-2.6-2.0-1.7-1.2-1.6-1.5
Compulsive drug intake0.70.71.71.21.20.60.71.0-0.21.3-1.21.30.30.50.51.10.20.81.20.70.70.20.60.5
One hour access (0.3 mA shock)0.40.51.4-0.8-0.30.50.50.21.2-0.81.1-0.80.90.50.6-0.00.8-1.2-0.30.50.50.80.60.7
One hour access (shock baseline)1.41.74.9-2.1-1.8-0.5-0.5-1.20.9-2.22.2-2.10.2-0.5-0.3-1.40.1-1.9-1.8-0.6-0.50.3-0.4-0.2
Number of responses in last shaping day1.11.11.9-1.1-1.3-1.0-1.1-1.2-0.3-1.20.9-1.2-0.8-1.1-0.9-1.3-0.9-0.5-1.4-1.2-1.1-0.8-1.1-1.0
Context. condit. distance diff. score0.50.71.60.80.6-0.7-0.7-0.1-1.10.8-1.10.7-1.0-0.7-0.8-0.0-1.11.20.3-0.6-0.7-1.3-0.6-0.8
Locomotion velocity, session 10.20.30.70.2-0.2-0.5-0.5-0.5-0.80.1-0.30.1-0.8-0.6-0.7-0.4-0.60.2-0.2-0.6-0.5-0.7-0.5-0.6
Locomotion distance, session 11.01.32.2-0.6-1.0-1.3-1.3-1.4-1.3-0.50.2-0.5-1.5-1.4-1.5-1.3-1.2-0.2-1.0-1.4-1.3-1.2-1.2-1.2
Locomotion velocity, session 22.32.74.3-0.4-1.3-1.9-1.9-1.8-2.0-0.4-0.2-0.5-2.1-2.0-1.9-1.6-1.90.4-1.2-1.9-1.9-1.8-2.0-2.1
Locomotion distance, session 20.91.32.7-1.0-1.4-1.1-1.2-1.7-1.1-0.80.8-0.8-1.3-1.2-1.4-1.5-0.8-0.9-1.2-1.3-1.1-0.9-1.0-1.0
Locomotion velocity, session 31.01.12.1-0.2-0.8-1.1-1.2-1.2-1.4-0.1-0.2-0.2-1.4-1.4-1.4-1.0-1.30.4-0.7-1.3-1.2-1.2-1.3-1.3
Locomotion distance, session 31.61.83.3-0.1-0.8-1.5-1.5-1.4-1.80.0-0.4-0.1-1.8-1.6-1.8-1.2-1.60.6-0.8-1.6-1.6-1.7-1.5-1.6
Stereotopy head waving bouts, day 30.10.10.30.20.10.40.40.40.10.3-0.20.30.40.30.50.40.40.20.30.40.40.50.10.1
Stereotopy head waving duration, day 30.30.40.80.40.50.70.70.80.50.4-0.30.40.80.60.90.80.60.40.60.70.70.80.40.4
Locomotion velocity, session 70.30.41.1-1.0-0.50.20.2-0.20.8-1.01.0-1.00.40.20.2-0.40.4-1.0-0.60.00.20.30.20.3
Locomotion distance, session 70.10.20.3-0.4-0.3-0.3-0.3-0.40.0-0.60.4-0.5-0.3-0.4-0.3-0.5-0.3-0.6-0.5-0.4-0.3-0.4-0.3-0.3
Stereotopy head waving bouts, day 70.00.00.00.0-0.10.00.0-0.0-0.10.1-0.00.0-0.0-0.00.0-0.00.00.2-0.0-0.00.00.0-0.1-0.1
Stereotopy head waving duration, day 70.40.51.4-0.9-0.50.50.5-0.11.0-0.81.2-0.90.70.50.5-0.20.8-0.9-0.50.30.50.80.50.6
Locomotion velocity, session 81.21.53.91.40.9-0.8-0.80.1-1.91.6-2.01.5-1.4-0.8-1.10.3-1.42.00.9-0.6-0.8-1.5-0.6-0.9
Locomotion distance, session 81.62.46.20.70.1-1.6-1.6-0.9-2.51.0-1.61.0-2.2-1.7-1.9-0.7-2.11.60.1-1.5-1.6-2.2-1.5-1.7
Degree of sensitization distance1.11.12.50.10.91.11.21.31.6-0.10.2-0.01.51.21.41.01.0-0.50.61.21.21.11.11.1
Degree of sensitization stereotypy0.10.10.3-0.4-0.20.10.0-0.10.4-0.40.5-0.50.20.00.1-0.20.1-0.3-0.4-0.10.10.10.00.1
Condit. Reinf. active minus inactive responses0.91.03.51.30.7-0.5-0.50.0-1.91.7-1.81.7-1.1-0.5-0.70.4-0.81.31.0-0.3-0.4-0.9-0.3-0.5
Condit. Reinf. active-inactive response ratio0.50.51.91.00.7-0.1-0.10.3-1.11.3-1.41.3-0.5-0.1-0.20.6-0.41.00.90.1-0.1-0.4-0.1-0.2
Condit. Reinf. active responses0.50.62.61.10.60.30.20.2-1.31.6-1.21.6-0.40.2-0.00.70.20.41.10.40.20.10.40.2
Condit. Reinf. inactive responses0.50.51.10.80.40.90.80.4-0.31.0-0.30.90.30.80.60.71.0-0.40.90.80.80.90.80.8
Incentive salience index mean1.31.55.61.30.4-0.9-0.9-0.4-2.41.7-1.81.7-1.6-1.0-1.20.1-1.21.50.8-0.7-0.9-1.3-0.7-1.0
Condit. Reinf. lever presses0.60.83.30.90.2-0.7-0.7-0.5-1.81.1-1.21.1-1.3-0.8-1.0-0.1-0.90.90.5-0.6-0.7-1.0-0.5-0.7
Time in familiar zone, hab. session 10.20.20.3-0.3-0.5-0.4-0.5-0.5-0.3-0.60.2-0.4-0.4-0.5-0.3-0.5-0.4-0.1-0.5-0.5-0.5-0.3-0.5-0.5
Time in novel zone, hab. session 10.90.91.60.10.71.21.21.01.10.50.20.21.21.11.00.91.2-0.50.71.11.21.11.21.3
Total zone transitions, hab. session 10.91.33.3-1.8-1.6-0.7-0.7-1.40.1-1.81.7-1.7-0.5-0.7-0.8-1.5-0.2-1.4-1.6-0.9-0.7-0.3-0.6-0.4
Total locomotion distance, hab. session 10.20.31.00.80.5-0.2-0.20.2-0.70.8-1.00.9-0.4-0.1-0.30.3-0.41.00.6-0.1-0.2-0.5-0.1-0.2
Locomotion velocity, hab. session 10.30.51.60.90.5-0.5-0.40.1-1.00.8-1.10.9-0.7-0.4-0.60.2-0.71.20.6-0.3-0.5-0.8-0.4-0.5
Time in familiar zone, hab. session 22.62.74.60.61.42.02.01.71.60.60.10.81.82.01.91.61.9-0.81.31.92.01.82.12.1
Time in novel zone, hab. session 22.12.13.4-0.9-1.5-1.7-1.8-1.7-1.5-0.70.2-0.8-1.6-1.7-1.7-1.6-1.50.3-1.3-1.7-1.7-1.4-1.8-1.8
Total zone transitions, hab. session 20.81.03.0-1.6-1.3-0.3-0.3-1.10.5-1.51.7-1.6-0.1-0.3-0.4-1.20.2-1.7-1.4-0.6-0.30.0-0.2-0.0
Total locomotion distance, hab. session 20.00.00.10.1-0.0-0.2-0.2-0.2-0.30.1-0.10.1-0.3-0.1-0.3-0.1-0.20.1-0.0-0.2-0.2-0.3-0.1-0.1
Locomotion velocity, hab. session 20.00.10.20.0-0.1-0.3-0.3-0.3-0.3-0.1-0.0-0.0-0.3-0.3-0.4-0.3-0.30.1-0.2-0.3-0.3-0.4-0.3-0.3
Novel to familiar place preference ratio0.70.71.41.11.00.80.81.00.01.1-0.91.20.60.80.91.10.60.31.20.90.80.70.70.6
Novelty place preference0.50.51.00.90.80.70.70.80.00.9-0.81.00.50.70.81.00.50.21.00.80.70.70.60.5
Time in novel zone, NPP test1.01.01.50.81.01.11.11.10.50.9-0.61.01.01.11.21.21.0-0.21.21.21.11.11.01.0
Total zone transitions, NPP test0.30.51.4-0.8-0.7-0.4-0.5-0.90.0-0.91.0-0.9-0.4-0.5-0.6-0.9-0.2-1.2-0.9-0.6-0.4-0.4-0.2-0.2
Total locomotion distance, NPP test0.20.20.70.80.5-0.2-0.20.1-0.70.8-0.80.8-0.5-0.2-0.40.2-0.30.50.5-0.1-0.1-0.5-0.0-0.1
Locomotion velocity, NPP test0.40.61.60.90.3-0.7-0.7-0.3-1.30.8-1.00.8-1.0-0.7-0.9-0.1-1.00.90.3-0.6-0.7-1.1-0.6-0.7
Pavlov. Cond. lever latency0.50.61.5-0.00.50.90.90.81.2-0.20.4-0.11.10.91.00.60.9-0.30.30.90.91.00.80.9
Pavlov. Cond. magazine entry latency0.10.20.70.40.2-0.4-0.4-0.1-0.80.6-0.60.6-0.6-0.3-0.50.0-0.40.30.3-0.2-0.3-0.6-0.1-0.2
Pavlov. Cond. change in total contacts0.10.10.50.10.0-0.3-0.3-0.3-0.70.4-0.30.4-0.6-0.3-0.5-0.2-0.40.10.1-0.3-0.3-0.5-0.1-0.2
Pavlov. Cond. index score0.10.10.40.1-0.1-0.3-0.3-0.3-0.60.2-0.30.2-0.5-0.2-0.4-0.1-0.3-0.10.1-0.2-0.3-0.4-0.1-0.2
Pavlov. Cond. latency score0.10.10.3-0.1-0.3-0.4-0.4-0.4-0.60.0-0.10.0-0.5-0.3-0.4-0.3-0.3-0.1-0.1-0.3-0.4-0.4-0.3-0.3
Pavlov. Cond. lever contacts0.10.10.30.0-0.2-0.3-0.3-0.3-0.60.1-0.10.1-0.5-0.3-0.4-0.2-0.30.0-0.1-0.3-0.3-0.4-0.2-0.3
Pavlov. Cond. magazine entry number0.00.00.20.20.20.10.10.20.3-0.00.0-0.10.20.00.10.1-0.00.4-0.00.00.10.00.00.0
Pavlov. Cond. intertrial magazine entries0.20.20.90.60.1-0.1-0.1-0.1-1.00.9-0.70.9-0.5-0.3-0.30.1-0.20.50.4-0.1-0.1-0.2-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.30.1-0.2-0.2-0.1-0.50.4-0.40.5-0.3-0.1-0.20.1-0.10.10.3-0.0-0.1-0.20.0-0.0
Pavlov. Cond. response bias0.20.31.00.1-0.2-0.6-0.6-0.5-1.00.4-0.40.4-0.8-0.5-0.6-0.3-0.50.20.1-0.5-0.5-0.6-0.4-0.4
Bone: apparent density1.93.25.40.51.12.22.21.61.60.70.20.82.02.12.11.72.3-1.31.32.12.22.32.22.2
Bone surface0.71.22.20.10.41.41.40.81.10.10.40.31.21.31.30.81.5-1.10.61.21.31.51.41.4
Bone volume1.52.55.1-0.50.21.91.90.91.9-0.41.2-0.31.91.81.90.92.2-2.10.41.71.92.31.81.9
Bone: connectivity density0.71.01.50.91.11.11.11.10.51.1-0.51.10.91.11.01.21.0-0.11.21.21.10.91.21.1
Bone: cortical apparent density3.64.66.9-1.1-1.9-2.6-2.6-2.4-2.2-1.00.2-1.0-2.5-2.5-2.6-2.3-2.40.7-1.8-2.6-2.6-2.4-2.5-2.5
Bone: cortical area3.65.414.5-2.3-1.22.22.10.33.2-2.23.1-2.12.62.12.40.13.1-3.8-0.91.72.13.21.92.2
Bone: cortical porosity0.70.81.41.00.90.80.81.00.11.0-0.91.10.60.90.91.10.60.61.21.00.80.80.70.6
Bone: cortical porosity1.21.32.11.11.21.21.21.40.41.2-0.91.21.01.31.21.51.00.51.41.31.21.11.11.0
Bone: cortical thickness1.22.06.2-1.9-1.41.00.9-0.31.7-1.82.2-1.81.30.91.1-0.41.6-2.5-1.00.60.91.80.60.9
Bone: cortical thickness0.50.61.9-1.4-1.2-0.1-0.1-0.80.5-1.31.3-1.30.1-0.1-0.0-0.80.3-1.2-1.1-0.3-0.10.4-0.3-0.1
Bone: cortical tissue density3.74.87.2-1.0-1.8-2.7-2.7-2.3-2.4-0.8-0.0-0.8-2.7-2.5-2.7-2.2-2.50.9-1.7-2.6-2.7-2.6-2.5-2.5
Bone: elastic displacement0.10.10.7-0.4-0.00.20.20.30.8-0.60.3-0.60.50.20.40.10.10.1-0.20.10.20.3-0.00.1
Bone: elastic work0.70.92.2-1.4-1.4-0.6-0.6-1.10.1-1.51.2-1.4-0.4-0.7-0.5-1.2-0.3-0.8-1.4-0.8-0.6-0.2-0.8-0.7
Bone: endosteal estimation0.71.54.1-0.7-0.11.31.20.41.6-0.81.4-0.71.41.31.20.31.7-2.0-0.11.11.31.61.31.5
Bone: endosteal perimeter2.14.314.3-2.6-1.51.51.4-0.32.8-2.63.4-2.52.01.41.6-0.62.4-3.8-1.51.01.42.41.31.7
Bone: final force1.01.76.4-1.9-1.40.70.6-0.61.4-1.82.2-1.80.90.60.7-0.71.3-2.5-1.20.30.61.40.50.7
Bone: final moment1.01.66.3-1.8-1.30.80.7-0.51.4-1.72.2-1.71.00.70.8-0.61.4-2.5-1.10.40.71.50.60.8
Bone: marrow area0.71.54.2-0.7-0.21.31.30.41.6-0.81.5-0.71.41.31.30.31.8-2.0-0.11.11.31.71.41.5
Bone: maximum diameter3.66.514.1-1.9-0.62.82.70.93.5-1.83.0-1.73.12.62.80.73.5-3.8-0.42.22.73.62.42.7
Bone: maximum force0.61.04.7-1.3-1.10.70.6-0.51.0-1.21.7-1.20.70.50.7-0.41.2-2.2-0.80.40.61.30.40.6
Bone: maximum moment0.61.04.4-1.1-0.90.80.7-0.31.0-1.11.5-1.00.80.60.8-0.31.3-2.1-0.60.50.71.40.60.7
Bone: minimum diameter1.93.46.9-1.2-0.32.02.00.72.6-1.32.1-1.22.31.92.10.62.6-2.6-0.21.72.02.61.82.0
Bone: periosteal estimation2.04.111.7-1.8-0.92.01.90.32.7-1.82.7-1.62.31.92.00.12.8-3.4-0.61.51.92.81.82.1
Bone: periosteal perimeter4.88.025.0-3.5-2.02.22.0-0.33.9-3.54.5-3.42.82.02.3-0.63.3-5.0-1.91.42.03.41.82.2
Bone: post-yield work0.71.03.01.61.30.60.60.9-0.51.6-1.31.70.10.60.31.10.30.81.40.70.60.20.80.6
Bone: stiffness0.40.73.4-1.1-1.00.30.2-0.60.7-1.11.4-1.20.50.30.4-0.60.8-1.8-0.90.10.21.00.10.3
Bone: tissue strength0.10.10.30.30.40.30.40.50.50.1-0.20.10.50.40.40.40.30.20.30.40.30.30.30.3
Bone: trabecular number1.62.53.90.61.21.91.91.61.40.9-0.10.91.71.91.81.61.9-0.71.41.91.91.82.02.0
Bone: trabecular spacing0.00.10.20.40.40.10.10.30.10.4-0.30.30.10.00.10.2-0.00.30.20.10.10.00.10.0
Bone: trabecular thickness2.73.26.9-1.4-0.32.01.90.72.5-1.22.1-1.32.21.92.00.52.4-2.6-0.21.61.92.41.82.0
Bone: trabecular tissue density0.81.12.3-1.5-1.5-0.8-0.9-1.3-0.3-1.31.0-1.3-0.6-0.9-0.6-1.3-0.5-1.0-1.4-1.0-0.9-0.4-1.0-0.9
Breakpoint value in progressive ratio session0.91.01.60.41.01.01.11.21.20.3-0.10.51.21.31.11.01.0-0.10.91.21.00.91.31.2
Distance traveled before self-admin1.71.82.9-0.6-0.9-1.6-1.6-1.4-1.1-0.60.3-0.7-1.5-1.6-1.7-1.5-1.60.5-1.3-1.7-1.6-1.7-1.5-1.5
Distance traveled after self-admin2.42.64.2-0.7-1.3-1.9-1.9-1.8-1.6-0.70.1-0.7-1.9-2.0-2.1-1.7-1.90.5-1.4-2.0-1.9-1.9-1.9-1.9
Delta time in closed arm before/after self-admin0.70.61.70.5-0.1-0.9-0.8-0.6-1.30.5-0.80.4-1.1-0.9-0.9-0.4-1.00.6-0.1-0.8-0.8-1.0-0.9-1.0
Delta time in open arm before/after self-admin1.51.43.20.10.41.11.11.21.5-0.00.30.21.71.81.51.11.7-0.50.81.61.11.61.31.4
Diff in mean of infusions in LGA sessions1.72.04.51.92.11.01.11.80.21.7-1.71.90.71.20.81.80.41.62.01.21.00.11.31.1
Extinction: sum of active levers before priming0.50.51.61.11.30.70.71.00.30.9-0.70.90.40.50.50.90.20.60.90.60.70.10.70.6
Active lever presses in extinction session 60.20.20.60.70.80.30.40.50.00.7-0.40.60.10.10.20.4-0.00.70.40.20.4-0.10.30.2
Delta distance traveled before/after self-admin0.20.30.4-0.6-0.7-0.4-0.4-0.6-0.3-0.60.4-0.6-0.5-0.6-0.5-0.6-0.4-0.3-0.6-0.5-0.4-0.4-0.5-0.4
Delta ambulatory time before/after self-admin0.00.00.1-0.1-0.10.20.1-0.1-0.0-0.10.1-0.2-0.1-0.1-0.0-0.1-0.0-0.3-0.1-0.10.10.10.0-0.0
Time in closed arm before self-admin0.40.41.0-0.8-0.6-0.4-0.5-0.70.2-0.90.9-1.0-0.3-0.7-0.5-0.8-0.5-0.4-1.0-0.7-0.4-0.5-0.5-0.4
Time in closed arm after self-admin1.01.01.8-0.3-0.6-1.2-1.2-1.0-0.9-0.3-0.0-0.4-1.2-1.3-1.3-1.0-1.40.3-0.9-1.3-1.2-1.3-1.3-1.3
Time in open arm before self-admin1.82.06.52.31.80.30.31.1-1.42.4-2.52.3-0.60.1-0.01.3-0.52.31.90.40.3-0.60.1-0.1
Time in open arm after self-admin1.21.32.81.31.20.90.91.40.11.4-1.31.50.81.31.01.50.91.11.71.30.90.81.00.9
Sum of active levers in priming session hrs 5-60.80.83.61.41.20.20.31.0-0.41.3-1.51.40.00.30.11.0-0.21.91.20.40.3-0.30.20.1
Time to tail flick, vehicle, before self-admin1.31.32.9-0.5-0.11.21.10.61.6-0.61.1-0.51.51.31.30.51.6-1.60.01.21.11.71.11.2
Time to tail flick, vehicle, after self-admin0.00.00.1-0.2-0.4-0.1-0.1-0.3-0.0-0.20.3-0.2-0.1-0.30.0-0.3-0.1-0.1-0.4-0.2-0.10.1-0.3-0.3
Time to tail flick, test, before self-admin3.63.55.7-1.5-2.1-2.0-2.1-2.4-1.6-1.30.9-1.3-2.0-2.2-2.1-2.3-1.7-0.6-2.0-2.2-2.1-1.7-2.1-2.0
Time to tail flick, test, after self-admin1.11.22.7-0.8-0.31.21.10.41.5-0.71.2-0.81.31.01.20.31.5-1.6-0.20.91.11.61.01.1
Delta time to tail flick, vehicle, before/after SA0.00.00.00.00.10.0-0.0-0.00.0-0.00.1-0.1-0.1-0.2-0.0-0.1-0.20.2-0.1-0.20.0-0.1-0.1-0.1
Delta time to tail flick, test, before/after SA3.12.75.70.00.62.02.01.52.1-0.10.7-0.12.21.92.21.32.2-1.20.81.92.02.41.81.9
Ambulatory time before self-admin0.90.91.4-0.6-0.9-1.2-1.2-1.1-0.6-0.60.5-0.7-0.9-1.1-1.2-1.2-1.0-0.0-1.1-1.2-1.2-1.0-1.1-1.0
Ambulatory time after self-admin1.82.03.3-0.6-1.1-1.6-1.6-1.5-1.3-0.70.2-0.7-1.6-1.7-1.8-1.5-1.60.5-1.3-1.7-1.6-1.7-1.6-1.6
Total heroin consumption0.81.02.2-0.30.51.21.20.81.5-0.20.8-0.21.31.11.10.61.3-1.00.31.01.21.21.31.3
Area under the delay curve0.80.92.6-0.90.21.01.00.31.6-0.91.4-0.71.00.60.70.10.8-1.6-0.40.51.00.91.01.1
Delay disc. indifference point, 0s delay0.40.41.4-1.0-0.50.00.0-0.30.9-1.01.2-1.00.3-0.1-0.1-0.50.1-1.1-0.9-0.20.10.20.10.2
Delay disc. indifference point, 16s delay0.50.51.1-0.20.60.90.90.61.1-0.20.6-0.10.70.50.70.40.6-0.80.20.61.00.51.01.0
Delay disc. indifference point, 2s delay0.20.20.5-0.5-0.1-0.3-0.3-0.40.1-0.50.5-0.5-0.4-0.7-0.6-0.6-0.6-0.2-0.7-0.6-0.3-0.7-0.2-0.2
Delay disc. indifference point, 24s delay1.11.12.60.21.01.51.51.01.30.20.40.21.10.81.30.91.0-1.00.51.01.61.11.31.3
Delay disc. indifference point, 4s delay0.10.10.4-0.20.40.20.20.20.6-0.30.4-0.30.20.1-0.1-0.0-0.0-0.0-0.10.00.2-0.20.30.4
Delay disc. indifference point, 8s delay2.72.810.7-2.1-0.81.21.1-0.22.5-2.12.9-2.01.60.81.1-0.51.6-3.3-1.30.71.21.71.21.5
Delay discount exponential model param0.80.92.60.9-0.1-1.0-1.0-0.3-1.60.9-1.40.8-1.0-0.5-0.7-0.0-0.81.60.4-0.5-1.0-0.8-1.0-1.1
Delay discount hyperbolic model param0.60.61.90.9-0.1-0.8-0.8-0.2-1.40.9-1.30.7-0.8-0.4-0.50.1-0.61.30.5-0.3-0.8-0.6-0.8-0.9
Fecal boli incidents, locomotor time 10.70.72.3-0.9-0.60.70.60.01.2-1.11.2-1.01.00.41.0-0.10.9-1.5-0.60.50.71.30.30.4
Change in fecal boli incidents, locomotor task2.01.96.12.21.7-0.3-0.20.9-1.52.3-2.52.2-0.70.2-0.51.1-0.62.51.80.2-0.1-1.00.1-0.1
Time >=10cm from walls, locomotor time 11.31.36.31.91.2-0.2-0.20.7-1.31.7-2.11.7-0.6-0.1-0.30.9-0.62.51.30.0-0.2-0.8-0.3-0.5
Bouts of movement, locomotor time 11.01.13.2-1.0-0.11.11.10.31.8-0.91.5-1.11.30.61.10.11.1-1.6-0.50.61.21.30.91.0
Total resting periods, locomotor time 10.60.72.2-1.0-0.40.70.6-0.11.4-1.01.5-1.20.80.20.6-0.30.7-1.4-0.80.20.80.90.40.6
Rest time, locomotor task time 11.21.32.9-1.5-1.6-0.8-0.9-1.4-0.1-1.51.4-1.5-0.6-1.1-0.8-1.5-0.6-1.1-1.7-1.1-0.9-0.4-1.1-1.0
Distance moved, locomotor task time 10.40.41.10.81.00.60.70.80.30.7-0.60.60.40.40.60.80.20.80.70.50.70.10.60.5
Vertical activity count, locomotor time 10.80.94.11.31.0-0.2-0.20.4-1.11.3-1.51.3-0.8-0.5-0.40.5-0.92.00.8-0.3-0.2-1.0-0.2-0.4
Time >=10cm from walls, locomotor time 20.80.92.11.51.30.90.91.0-0.11.4-1.11.20.30.50.71.10.41.01.20.71.00.40.60.5
Bouts of movement, locomotor time 20.10.10.50.20.2-0.4-0.40.0-0.10.0-0.30.1-0.3-0.4-0.3-0.1-0.70.6-0.1-0.4-0.4-0.7-0.3-0.4
Total resting periods, locomotor time 20.10.10.2-0.3-0.1-0.3-0.3-0.10.4-0.40.3-0.4-0.1-0.3-0.2-0.3-0.50.1-0.4-0.3-0.3-0.5-0.2-0.2
Rest time, locomotor task time 20.60.72.2-1.4-1.0-0.3-0.3-0.70.7-1.51.3-1.30.1-0.3-0.2-0.9-0.0-1.1-1.2-0.4-0.30.1-0.4-0.2
Distance moved, locomotor task time 20.20.30.80.30.50.90.80.50.50.40.10.20.50.30.70.50.5-0.10.30.40.90.60.60.6
Vertical activity count, locomotor time 20.10.10.40.50.40.50.50.3-0.30.6-0.40.6-0.0-0.00.30.40.10.30.40.10.50.30.20.1
Weight adjusted by age3.13.512.6-2.8-1.80.60.5-0.72.4-2.73.3-2.61.50.81.0-1.01.7-3.6-1.70.50.51.80.91.2
Seeking ratio, delayed vs. immediate footshock1.11.23.30.7-0.0-1.0-1.0-0.7-1.80.7-1.10.6-1.6-1.2-1.3-0.5-1.51.20.0-1.1-1.0-1.5-1.1-1.3
Locomotion in novel chamber1.41.83.3-0.3-1.0-1.7-1.7-1.3-1.8-0.3-0.5-0.2-1.8-1.3-1.7-1.2-1.50.9-0.6-1.5-1.8-1.7-1.4-1.5
Locomotion in novel chamber post-restriction2.93.47.70.2-0.9-2.1-2.1-1.7-2.80.4-1.00.0-2.6-2.2-2.1-1.4-2.31.4-0.7-2.1-2.1-2.3-2.2-2.3
Progressive ratio0.40.51.71.00.8-0.1-0.00.6-0.61.1-1.31.1-0.20.1-0.00.6-0.31.30.90.20.0-0.3-0.1-0.1
Food seeking constrained by brief footshock0.70.82.81.41.70.80.91.00.11.4-1.01.30.30.30.51.0-0.00.91.00.50.9-0.00.70.6
Seeking ratio, punishment vs. effort0.10.10.5-0.5-0.2-0.0-0.0-0.30.4-0.50.7-0.6-0.1-0.3-0.1-0.5-0.2-0.7-0.6-0.3-0.1-0.1-0.1-0.0
Run reversals in cocaine runway, females0.40.41.3-1.1-1.1-0.4-0.4-0.50.2-1.10.7-0.70.20.40.0-0.40.5-1.0-0.40.1-0.50.4-0.10.0
Run reversals in cocaine runway, males0.50.51.70.50.6-0.2-0.20.0-0.40.4-0.60.1-0.7-1.2-0.4-0.1-1.31.3-0.2-0.8-0.1-0.9-0.8-0.9
Latency to leave start box in cocaine runway0.20.20.90.20.60.40.50.70.90.00.00.00.80.50.50.50.20.10.20.50.50.30.40.4
Latency to leave start box in cocaine runway, F0.10.20.50.50.70.30.30.70.50.4-0.40.30.40.20.40.5-0.00.70.30.30.40.10.10.1
Latency to leave start box in cocaine runway, M0.70.62.1-1.2-0.8-0.1-0.0-0.41.1-1.41.4-1.50.50.00.1-0.70.3-1.4-1.0-0.1-0.10.30.00.2
Cd content in liver1.01.14.21.71.1-0.3-0.30.5-1.31.7-1.91.6-0.7-0.4-0.40.7-0.92.11.1-0.2-0.3-0.9-0.4-0.6
Co content in liver0.40.50.9-0.1-0.6-0.8-0.8-0.9-0.9-0.1-0.0-0.2-0.9-0.9-0.8-0.7-0.80.2-0.5-0.9-0.9-0.7-0.9-0.9
Cu content in liver0.30.30.7-0.8-0.8-0.4-0.5-0.7-0.2-0.70.6-0.6-0.4-0.6-0.4-0.8-0.3-0.4-0.8-0.6-0.5-0.3-0.5-0.5
Fe content in liver0.30.30.90.90.60.40.40.5-0.31.0-0.80.90.10.30.30.60.20.60.80.40.30.30.30.2
K content in liver0.00.00.1-0.2-0.1-0.1-0.1-0.10.2-0.20.2-0.3-0.0-0.3-0.1-0.2-0.30.1-0.4-0.3-0.1-0.2-0.3-0.3
Mg content in liver0.30.31.2-0.6-0.10.60.60.31.1-0.60.7-0.70.70.20.60.00.3-0.5-0.40.20.50.50.20.3
Mn content in liver0.30.30.80.10.1-0.7-0.6-0.2-0.50.1-0.50.1-0.6-0.7-0.7-0.3-0.90.7-0.1-0.6-0.7-0.9-0.6-0.6
Na content in liver0.20.20.8-0.20.30.60.60.60.9-0.40.2-0.10.70.40.60.40.4-0.10.10.40.60.40.50.6
Rb content in liver0.20.20.80.60.80.20.20.70.30.4-0.60.40.30.10.30.6-0.20.90.50.20.2-0.10.00.0
Se content in liver0.10.20.30.50.60.50.50.50.10.6-0.30.50.30.30.40.50.30.40.40.30.50.30.40.4
Sr content in liver2.01.93.70.2-0.3-1.8-1.8-1.1-1.40.1-0.5-0.0-1.6-1.8-1.7-1.0-1.91.0-0.7-1.5-1.8-1.8-1.5-1.6
Zn content in liver1.21.42.9-0.2-0.5-1.4-1.3-1.0-1.0-0.2-0.3-0.3-1.3-1.6-1.3-1.0-1.70.8-0.9-1.4-1.4-1.5-1.5-1.6