Hub : Genes

Mertk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000097978 0.04 0.03 1.0e-03 0.02 0.01 0.01 0.01 3.0e-03 1.0e-02 4.1e-02 1.0e-02
2 Adipose alternative TSS ENSRNOT00000107394 0.11 0.1 5.2e-08 0.04 0.06 0.05 0.05 2.9e-05 6.6e-07 2.5e-06 5.7e-06
3 Adipose gene expression ENSRNOG00000017319 0.32 0.18 0.0e+00 0.16 0.17 0.16 0.17 2.9e-17 8.4e-19 4.3e-17 3.5e-18
4 Adipose mRNA stability ENSRNOG00000017319 0.06 0.04 4.8e-06 0.03 0.04 0.04 0.04 1.4e-04 1.1e-05 1.2e-05 4.7e-05
5 BLA gene expression ENSRNOG00000017319 0.26 0.14 1.6e-09 0.06 0.17 0.18 0.17 2.6e-04 1.4e-09 5.8e-10 2.3e-09
6 BLA mRNA stability ENSRNOG00000017319 0.09 0.07 3.3e-03 0.01 0.01 0.01 0.01 1.1e-01 5.3e-02 7.3e-02 1.4e-01
7 Brain gene expression ENSRNOG00000017319 0.25 0.13 2.8e-16 0.06 0.16 0.16 0.16 2.2e-06 7.0e-15 8.2e-15 8.7e-15
8 Brain mRNA stability ENSRNOG00000017319 0.24 0.18 2.7e-09 0.08 0.09 0.06 0.09 5.4e-08 2.0e-08 6.0e-06 9.3e-09
9 IL mRNA stability ENSRNOG00000017319 0.24 0.16 3.4e-03 0.03 0.03 0.08 0.05 6.2e-02 7.7e-02 6.4e-03 2.9e-02
10 Liver gene expression ENSRNOG00000017319 0.19 0.09 0.0e+00 0.09 0.09 0.11 0.11 4.7e-10 1.3e-10 2.5e-12 6.7e-12
11 Liver mRNA stability ENSRNOG00000017319 0.1 0.06 1.8e-08 0.06 0.06 0.05 0.06 1.8e-07 4.9e-07 2.2e-06 1.8e-07
12 NAcc gene expression ENSRNOG00000017319 0.14 0.09 1.5e-06 0.06 0.08 0.07 0.07 3.0e-05 9.9e-07 2.9e-06 5.9e-06
13 NAcc mRNA stability ENSRNOG00000017319 0.12 0.08 5.7e-06 0.02 0.06 0.08 0.06 1.9e-02 2.0e-05 2.8e-06 5.1e-05
14 OFC mRNA stability ENSRNOG00000017319 0.32 0.17 1.9e-04 0.02 0.06 0.11 0.12 9.5e-02 1.9e-02 1.2e-03 1.1e-03
15 PL gene expression ENSRNOG00000017319 0.18 0.11 4.3e-09 0.03 0.11 0.09 0.09 3.4e-03 1.4e-08 1.7e-07 2.6e-07
16 PL mRNA stability ENSRNOG00000017319 0.1 0.07 7.1e-05 0.05 0.05 0.04 0.05 6.7e-05 7.3e-05 6.9e-04 1.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail0.41.35.0-1.11.00.6-0.2-1.2-0.2-0.5-1.4-1.21.9-1.3-0.7-0.3-2.2-0.6-1.3
BMI without tail1.12.39.9-1.51.21.30.2-1.30.1-0.3-1.8-0.82.9-1.8-0.7-0.1-3.1-0.4-1.8
Body weight1.14.727.0-1.60.33.21.8-0.61.61.0-1.60.25.2-1.60.41.3-4.30.8-1.6
Epididymis fat weight0.10.31.7-0.60.40.70.2-0.50.20.0-0.70.01.2-0.6-0.10.3-1.3-0.0-0.5
Glucose0.20.30.80.3-0.40.70.70.30.60.60.20.50.90.30.50.3-0.30.50.3
Heart weight3.34.710.30.9-1.93.22.81.62.72.50.92.33.11.02.22.8-1.22.30.9
Left kidney weight1.64.57.51.6-2.12.62.52.12.52.41.62.41.91.72.32.7-0.12.41.7
Right kidney weight1.33.86.31.4-1.92.42.32.02.32.21.52.31.71.52.12.5-0.02.21.6
Tail length1.13.315.8-1.90.92.10.8-0.90.80.2-1.90.14.0-1.8-0.20.6-3.80.1-1.9
Length with tail1.24.317.0-0.2-1.13.42.61.02.52.0-0.01.74.10.01.62.5-2.51.9-0.0
Length without tail0.71.52.80.5-1.21.71.61.11.51.40.71.21.60.71.31.6-0.41.30.7
Liver weight, left2.23.66.81.8-2.11.72.12.02.02.21.82.60.81.82.11.80.92.11.8
Liver weight, right0.00.00.20.4-0.1-0.1-0.1-0.1-0.1-0.00.30.0-0.40.30.00.10.20.00.3
Parametrial fat weight0.20.30.7-0.20.4-0.8-0.7-0.5-0.7-0.6-0.3-0.6-0.7-0.3-0.6-0.80.3-0.6-0.3
Retroperitoneal fat weight0.10.40.80.8-0.50.50.50.40.50.60.60.90.10.70.60.80.20.60.8
Intraocular pressure0.40.61.1-1.10.9-0.3-0.6-0.8-0.6-0.7-0.9-0.30.5-1.0-0.8-0.8-0.9-0.7-0.9
Extensor digitorum longus weight0.10.51.3-1.10.70.0-0.3-0.6-0.3-0.4-0.9-0.20.8-0.9-0.5-0.8-1.1-0.5-0.9
Soleus weight0.30.82.30.5-0.81.21.10.81.11.10.51.51.10.50.90.9-0.31.00.5
Tibialis anterior weight0.31.05.3-1.30.21.40.8-0.10.70.4-0.90.32.3-1.00.1-0.1-1.90.3-1.0
Tibia length2.15.915.8-3.22.40.4-0.9-2.4-1.0-1.5-3.3-1.93.0-3.3-1.9-1.1-4.0-1.7-3.3
Number of licking bursts0.30.30.9-0.80.6-0.1-0.3-0.5-0.4-0.3-0.70.40.6-0.7-0.5-0.7-0.9-0.3-0.7
Food consumed during 24 hour testing period0.40.50.90.8-0.7-0.00.30.70.30.50.80.9-0.70.90.60.51.00.50.8
Times rat made contact with spout0.00.00.20.1-0.1-0.10.00.2-0.00.10.20.5-0.20.20.10.10.20.10.2
Mean time between licks in bursts0.40.51.0-0.60.8-0.8-0.8-0.7-0.8-0.8-0.7-0.7-0.4-0.7-0.8-1.0-0.2-0.8-0.7
Mean num. licks in bursts0.70.81.61.1-1.00.20.61.00.60.71.20.3-0.81.20.81.01.30.71.2
Std. dev. time between licks in bursts0.20.31.3-0.2-0.10.90.60.10.60.4-0.20.51.1-0.20.30.5-0.90.4-0.2
Water consumed over 24 hours0.10.20.3-0.50.5-0.4-0.4-0.4-0.5-0.4-0.4-0.1-0.1-0.4-0.5-0.3-0.3-0.5-0.4
Indifference point 0 sec1.82.83.91.8-1.91.51.81.81.81.81.71.50.61.81.82.01.01.81.7
Indifference point AUC0.10.10.40.0-0.20.50.40.10.40.30.00.00.60.00.20.4-0.30.3-0.0
Indifference point function ln k0.60.91.40.8-0.91.21.10.91.11.10.71.00.80.81.01.10.01.10.8
Indifference point function log k0.60.91.40.8-0.91.21.10.91.11.10.71.00.80.81.01.10.01.10.8
Delay discounting total patch changes 0 sec1.93.14.01.9-2.01.51.91.91.91.91.81.50.51.91.92.01.11.91.8
Delay discounting total patch changes 12 sec0.00.00.00.0-0.1-0.00.00.00.00.00.0-0.20.10.10.00.20.2-0.00.0
Delay discounting total patch changes 18 sec1.62.13.51.9-1.60.61.11.61.11.31.81.2-0.61.81.41.51.81.41.7
Delay discounting total patch changes 24 sec3.64.56.12.4-2.41.11.92.51.92.12.42.3-0.42.42.22.02.22.22.4
Delay discounting total patch changes 6 sec1.52.33.11.4-1.61.71.81.51.81.71.41.40.91.41.71.80.51.71.5
Delay discounting time to switch 0 sec2.94.48.3-1.42.0-2.9-2.6-1.8-2.6-2.5-1.3-2.2-2.4-1.4-2.2-2.50.5-2.4-1.3
Delay discounting water rate 0 sec3.65.811.71.4-2.23.43.12.03.02.81.42.43.11.52.52.8-0.92.71.4
Delay discounting water rate 12 sec1.52.23.50.9-1.41.91.81.51.81.71.01.81.41.11.61.8-0.11.71.0
Delay discounting water rate 18 sec0.10.20.7-0.1-0.00.60.3-0.10.30.3-0.10.50.8-0.10.10.5-0.80.2-0.1
Delay discounting water rate 24 sec0.20.21.2-0.10.00.70.4-0.10.30.2-0.30.21.1-0.20.10.4-1.00.2-0.3
Delay discounting water rate 6 sec0.71.03.80.1-0.61.61.20.51.21.00.00.92.00.10.81.1-1.10.90.1
Locomotor activity0.10.21.4-0.20.10.60.3-0.10.30.1-0.4-0.21.2-0.30.00.6-0.80.1-0.3
Locomotor testing distance0.20.41.10.6-0.60.50.60.70.60.60.50.50.30.60.61.10.30.60.5
Locomotor testing rearing1.42.23.91.2-1.51.81.81.51.81.71.21.31.11.21.72.00.21.71.2
Light reinforcement 10.20.31.7-0.3-0.00.90.60.00.50.4-0.20.21.3-0.20.20.5-1.00.3-0.2
Light reinforcement 20.10.10.6-0.2-0.00.50.3-0.00.30.2-0.20.10.8-0.20.1-0.2-0.70.2-0.2
Reaction time number correct0.60.91.91.1-1.00.91.00.81.01.01.01.40.41.01.00.80.41.00.8
Reaction time mean minus median0.20.31.50.4-0.3-0.6-0.20.3-0.2-0.00.60.1-1.20.60.1-0.01.20.00.5
Reaction time mean minus median AUC0.20.20.90.4-0.4-0.20.10.40.10.20.60.4-0.80.60.30.00.90.20.5
Reaction time num false alarms1.72.34.90.7-1.42.22.01.42.01.80.81.22.00.81.61.8-0.61.70.8
Reaction time num false alarms AUC0.91.23.80.3-0.91.81.50.81.41.20.30.62.00.31.11.3-0.91.10.2
Reaction time trials correct on left0.60.91.91.1-1.00.91.00.81.01.01.01.40.41.01.00.80.41.00.8
Reaction time trials on left0.60.91.91.1-1.00.91.00.81.01.01.01.40.41.01.00.80.31.00.8
Reaction time mean0.00.00.1-0.20.20.1-0.1-0.3-0.1-0.1-0.2-0.30.2-0.2-0.10.1-0.2-0.1-0.2
Reaction time mean AUC0.00.00.1-0.20.20.0-0.1-0.3-0.1-0.1-0.1-0.30.2-0.2-0.10.1-0.2-0.1-0.2
Median of all reaction times0.10.10.4-0.20.10.40.2-0.30.10.0-0.2-0.20.7-0.2-0.00.3-0.50.0-0.1
Reaction time omissions0.20.30.80.3-0.50.90.70.40.80.60.40.30.50.30.60.5-0.20.60.4
Reaction time false alarm rate0.40.52.1-0.2-0.51.20.90.50.90.7-0.0-0.11.5-0.00.60.9-0.80.7-0.0
Reaction time premature initiation rate0.20.30.8-0.70.5-0.0-0.2-0.4-0.3-0.3-0.80.30.8-0.7-0.4-0.0-0.9-0.3-0.7
Reaction time premature initiations0.10.21.00.0-0.10.30.30.20.20.3-0.11.00.7-0.10.20.4-0.40.2-0.1
Std. dev. reaction times0.10.10.2-0.30.20.1-0.1-0.3-0.1-0.1-0.3-0.40.4-0.3-0.20.2-0.4-0.1-0.3
Reaction time trials completed0.60.91.91.1-1.00.91.00.81.01.01.01.40.41.01.00.80.31.00.8
Reaction time trials AUC0.60.91.81.1-1.00.91.00.81.01.01.01.30.41.01.00.90.31.00.8
Social response proportion0.70.71.30.8-1.01.11.11.01.11.00.60.70.60.61.00.50.11.00.7
Social responses0.40.52.7-0.4-0.21.20.80.10.80.5-0.4-0.11.6-0.40.30.2-1.20.4-0.4
Social time0.10.20.6-0.50.30.0-0.2-0.3-0.1-0.3-0.4-0.80.1-0.5-0.3-0.6-0.4-0.3-0.4
Conditioned locomotion2.02.44.40.9-1.62.12.01.52.01.81.11.51.51.11.71.6-0.21.81.2
Cocaine response after cond. corrected0.30.30.60.6-0.60.10.40.60.40.40.60.4-0.20.70.50.80.70.40.8
Cocaine response after cond. not corrected0.20.20.50.6-0.4-0.10.10.40.10.20.5-0.1-0.40.60.30.50.70.20.7
Cocaine response before conditioning0.20.31.1-0.10.4-0.7-0.6-0.5-0.6-0.6-0.2-1.0-0.6-0.2-0.5-0.60.2-0.6-0.2
Saline control response1.01.36.6-0.5-0.41.91.30.31.21.0-0.30.82.6-0.30.70.7-1.80.8-0.4
Condit. Reinf. active minus inactive responses1.72.15.10.6-1.12.31.91.11.81.60.51.12.20.61.41.9-1.01.50.4
Condit. Reinf. active-inactive response ratio1.51.55.10.2-0.82.01.60.71.51.30.21.12.30.21.11.5-1.31.20.1
Condit. Reinf. active responses1.31.96.10.3-0.92.31.80.81.81.40.20.92.50.21.21.5-1.41.40.2
Condit. Reinf. inactive responses0.20.30.80.3-0.50.90.70.50.70.60.30.30.80.30.60.5-0.30.60.3
Condit. Reinf. lever presses0.30.41.8-0.70.20.90.5-0.10.50.2-0.50.11.3-0.50.10.2-1.30.2-0.6
Condit. Reinf. lever reinforcers received1.41.95.30.4-1.02.31.81.01.81.50.41.02.30.41.31.5-1.21.50.3
Pavlov. Cond. lever latency0.70.94.80.40.1-1.7-1.0-0.2-1.0-0.70.4-0.3-2.20.4-0.5-0.81.7-0.70.5
Pavlov. Cond. magazine entry latency0.20.20.40.1-0.50.60.60.60.60.60.30.60.30.40.50.40.10.60.2
Pavlov. Cond. change in total contacts0.40.52.9-0.60.21.10.5-0.20.50.2-0.6-0.11.7-0.60.00.2-1.50.2-0.7
Pavlov. Cond. index score0.50.63.1-0.70.11.20.7-0.00.70.4-0.60.11.8-0.60.20.3-1.50.3-0.7
Pavlov. Cond. latency score0.40.52.2-0.4-0.21.20.80.30.80.6-0.30.31.5-0.20.40.5-1.10.5-0.4
Pavlov. Cond. lever contacts0.71.04.7-0.4-0.21.71.10.21.10.8-0.30.42.2-0.30.50.7-1.60.7-0.4
Pavlov. Cond. magazine entry number0.20.21.00.4-0.1-0.6-0.30.0-0.3-0.20.4-0.1-1.00.4-0.0-0.20.8-0.10.5
Pavlov. Cond. intertrial magazine entries0.20.31.00.7-0.50.20.40.50.40.50.61.0-0.30.60.50.30.50.50.6
Pavlov. Cond. lever-magazine prob. diff.0.40.52.3-0.70.11.10.5-0.00.50.3-0.6-0.11.5-0.50.10.2-1.30.3-0.7
Pavlov. Cond. response bias0.71.05.2-0.5-0.21.81.10.21.10.8-0.40.42.3-0.40.50.7-1.70.7-0.5
Conditioned reinforcement - actives0.20.20.8-0.30.00.60.3-0.10.30.2-0.30.40.9-0.30.10.1-0.90.1-0.3
Conditioned reinforcement - inactives5.15.88.61.9-2.62.92.92.42.92.82.02.51.91.92.72.70.22.71.9
Conditioned locomotion0.10.10.6-0.1-0.10.60.40.00.40.3-0.10.40.7-0.20.20.1-0.50.3-0.1
Intermittent access intake day 1-15 change0.80.83.6-0.1-0.41.41.00.10.90.8-0.10.91.9-0.10.61.0-1.30.6-0.1
Intermittent access intake escalation0.60.62.9-0.1-0.41.20.90.00.80.7-0.10.81.7-0.10.50.8-1.20.5-0.1
Intermittent access intake escalation 20.10.10.7-0.1-0.20.60.40.00.40.3-0.10.40.8-0.10.20.4-0.60.2-0.1
Intermitt. access day 1 inactive lever presses1.61.73.00.8-1.41.71.71.21.61.60.91.21.40.91.41.7-0.11.40.8
Intermitt. access day 15 inactive lever presses4.95.47.22.2-2.62.22.62.52.52.62.22.71.12.22.62.61.02.52.2
Intermitt. access escalation Index1.51.42.8-1.11.2-1.3-1.3-0.9-1.3-1.4-1.0-1.7-0.8-1.0-1.3-1.2-0.1-1.3-1.1
Intermittent access day 1 total infusions0.10.10.3-0.20.2-0.6-0.4-0.1-0.4-0.3-0.1-0.3-0.6-0.2-0.3-0.40.4-0.3-0.2
Intermittent access day 15 total infusions0.30.41.50.0-0.40.90.70.20.70.60.10.71.20.00.50.7-0.70.50.0
Intermittent access terminal intake (last 3 days)0.80.91.60.6-1.01.11.10.81.11.10.71.30.90.61.01.1-0.11.00.6
Intermittent access total infusions0.60.61.40.6-0.90.70.90.80.80.90.71.20.50.60.90.90.30.90.6
Intermittent access day 1 locomotion0.20.20.40.2-0.40.60.60.40.60.50.20.50.50.20.50.2-0.10.50.2
Intermittent access day 15 total locomotion2.22.43.41.3-1.71.81.81.51.81.81.31.71.11.31.71.60.31.71.3
Intermittent access total locomotion0.91.01.90.7-1.01.41.30.91.31.30.71.31.10.71.10.9-0.21.20.7
Intermittent access standard deviation0.10.10.4-0.2-0.00.40.2-0.10.20.2-0.20.30.6-0.20.1-0.0-0.60.1-0.2
Cocaine induced anxiety3.84.411.23.0-1.9-0.50.61.70.71.22.81.9-2.62.91.51.33.31.33.0
Post-drug Anxiety1.31.43.81.8-0.9-0.50.10.70.10.51.61.0-1.81.70.70.61.90.51.8
Baseline Anxiety0.80.82.2-1.30.80.1-0.3-0.8-0.4-0.5-1.2-0.61.2-1.3-0.7-0.5-1.5-0.6-1.3
Lifetime Intake0.30.30.70.3-0.60.60.70.40.60.70.30.80.60.30.60.5-0.10.60.3
Incentive Sensitization - Responses0.00.00.1-0.0-0.10.00.0-0.00.00.0-0.0-0.10.2-0.00.00.30.0-0.0-0.0
Incentive Sensitization - Breakpoint0.00.00.20.2-0.30.10.20.20.10.20.20.10.00.20.20.50.30.20.2
Progressive ratio test 1 active lever presses0.40.52.3-0.4-0.11.10.7-0.10.70.5-0.40.31.5-0.40.30.2-1.30.4-0.4
Progressive ratio test 1 breakpoint0.50.52.7-0.60.01.20.6-0.30.60.4-0.50.21.6-0.60.20.2-1.50.3-0.6
Progressive ratio test 1 inactive lever presses1.61.72.90.9-1.41.71.61.21.61.61.01.21.21.01.51.6-0.01.50.9
Progressive ratio test 2 active lever presses0.70.81.10.8-1.01.01.10.81.01.00.81.00.60.71.01.00.21.00.8
Progressive ratio test 2 breakpoint0.30.30.50.5-0.60.70.70.40.70.70.50.60.40.40.60.60.10.60.5
Progressive ratio test 2 inactive lever presses2.93.34.91.4-1.92.22.21.72.22.21.52.11.51.42.02.00.12.01.4
Total sessions with >9 infusions0.30.40.8-0.70.6-0.4-0.6-0.8-0.6-0.6-0.6-0.4-0.2-0.7-0.6-0.9-0.4-0.6-0.7
Short access day 1 total inactive lever presses0.10.20.40.2-0.40.60.50.30.50.50.20.20.50.20.40.6-0.20.40.2
Short access day 10 total inactive lever presses4.85.37.92.8-2.51.31.92.31.92.22.72.2-0.52.82.32.82.12.22.8
Short access day 1 total infusions0.00.00.0-0.20.0-0.1-0.0-0.0-0.0-0.0-0.1-0.0-0.1-0.1-0.0-0.10.0-0.0-0.2
Short access day 10 total infusions0.00.00.1-0.20.1-0.3-0.2-0.2-0.2-0.1-0.20.2-0.1-0.2-0.2-0.30.0-0.2-0.2
Short access total infusions0.10.10.2-0.40.2-0.1-0.1-0.3-0.2-0.1-0.30.10.0-0.3-0.2-0.4-0.2-0.2-0.4
Short access day 1 locomotion0.20.20.50.5-0.50.00.20.40.30.40.60.5-0.50.50.4-0.00.70.30.5
Short access day 10 total locomotion0.20.21.4-0.40.10.70.4-0.10.40.2-0.4-0.01.2-0.40.10.2-1.00.2-0.4
Short access total locomotion0.20.20.60.2-0.40.80.70.30.70.60.20.50.60.20.50.3-0.30.60.2
Compulsive drug intake0.60.61.4-0.50.7-1.2-1.0-0.6-1.0-0.9-0.5-0.7-0.9-0.5-0.8-0.90.4-0.9-0.5
One hour access (0.3 mA shock)0.60.71.60.3-0.91.21.10.71.01.00.40.81.30.40.90.8-0.30.90.3
One hour access (shock baseline)0.30.30.50.3-0.70.70.70.50.70.70.40.50.60.30.60.6-0.00.60.3
Number of responses in last shaping day0.00.00.10.00.0-0.2-0.1-0.1-0.1-0.10.0-0.0-0.0-0.0-0.1-0.30.1-0.10.0
Context. condit. distance diff. score2.63.25.81.6-1.72.22.21.62.12.11.42.41.51.52.01.2-0.02.11.5
Locomotion velocity, session 10.10.10.30.2-0.2-0.1-0.00.20.00.00.3-0.5-0.50.30.10.10.60.00.3
Locomotion distance, session 11.72.23.31.0-1.61.81.81.71.81.71.31.71.21.21.71.50.21.71.2
Locomotion velocity, session 20.10.10.3-0.30.1-0.3-0.20.0-0.2-0.2-0.2-0.5-0.2-0.2-0.2-0.40.2-0.2-0.3
Locomotion distance, session 22.12.95.60.9-1.72.42.21.82.22.01.11.52.01.11.91.8-0.31.91.1
Locomotion velocity, session 30.91.02.1-1.21.1-0.1-0.6-1.1-0.6-0.8-1.2-1.21.0-1.2-0.9-1.1-1.5-0.9-1.1
Locomotion distance, session 32.02.29.4-1.61.11.10.1-1.30.0-0.4-1.7-0.93.0-1.7-0.7-0.4-3.1-0.5-1.6
Stereotopy head waving bouts, day 32.63.25.72.3-1.90.41.21.91.31.52.21.5-1.42.31.71.72.41.62.2
Stereotopy head waving duration, day 30.60.73.01.0-0.7-0.40.10.80.20.31.10.4-1.61.10.50.31.70.41.0
Locomotion velocity, session 70.80.93.50.1-0.51.41.20.51.11.00.11.31.90.10.80.8-1.00.90.1
Locomotion distance, session 73.24.17.91.4-1.82.82.61.62.52.41.32.42.61.32.21.9-0.82.31.4
Stereotopy head waving bouts, day 70.50.61.0-0.90.8-0.6-0.7-0.7-0.7-0.8-0.9-1.0-0.0-0.8-0.8-0.5-0.4-0.8-0.9
Stereotopy head waving duration, day 71.21.52.5-1.11.2-1.3-1.4-1.3-1.4-1.4-1.2-1.6-0.7-1.1-1.4-1.0-0.2-1.4-1.2
Locomotion velocity, session 80.80.91.70.5-1.01.31.31.01.31.10.71.01.00.61.10.8-0.11.10.6
Locomotion distance, session 85.37.915.21.9-2.73.93.62.53.63.31.93.13.21.93.12.4-0.73.31.9
Degree of sensitization distance4.04.16.72.3-2.21.21.82.21.82.12.32.6-0.52.32.11.61.82.22.3
Degree of sensitization stereotypy2.12.33.7-1.91.6-0.6-1.2-1.6-1.2-1.4-1.9-1.80.8-1.9-1.5-1.1-1.6-1.5-1.9
Condit. Reinf. active minus inactive responses0.20.20.9-0.40.40.1-0.2-0.6-0.2-0.3-0.5-1.00.4-0.4-0.3-0.5-0.8-0.4-0.4
Condit. Reinf. active-inactive response ratio0.20.30.80.1-0.40.90.70.40.70.50.2-0.00.80.20.50.5-0.50.50.2
Condit. Reinf. active responses0.10.10.7-0.10.30.1-0.1-0.4-0.1-0.2-0.2-0.90.2-0.2-0.2-0.3-0.5-0.2-0.2
Condit. Reinf. inactive responses0.10.10.30.5-0.40.20.30.40.30.30.5-0.1-0.10.50.40.40.40.40.4
Incentive salience index mean0.10.10.30.2-0.30.60.40.20.40.30.2-0.10.30.20.30.1-0.30.30.2
Condit. Reinf. lever presses0.10.10.20.3-0.30.50.40.30.40.30.20.30.30.30.30.2-0.10.40.2
Time in familiar zone, hab. session 10.40.30.8-0.80.5-0.9-0.7-0.4-0.7-0.6-0.4-0.1-0.6-0.5-0.6-0.50.4-0.6-0.6
Time in novel zone, hab. session 11.31.32.41.5-1.11.31.20.91.31.21.20.80.41.21.20.90.21.21.3
Total zone transitions, hab. session 11.11.62.60.7-1.31.51.51.41.51.40.91.31.30.91.41.6-0.01.40.8
Total locomotion distance, hab. session 13.14.58.81.5-2.32.22.52.42.42.41.72.11.51.72.33.00.62.41.6
Locomotion velocity, hab. session 13.04.48.21.5-2.22.22.42.52.42.41.72.01.61.72.32.90.62.31.6
Time in familiar zone, hab. session 20.20.21.30.4-0.1-0.7-0.30.2-0.3-0.20.4-0.0-1.20.4-0.00.41.0-0.10.4
Time in novel zone, hab. session 20.20.21.3-0.40.20.60.3-0.20.30.1-0.5-0.21.1-0.5-0.0-0.4-1.00.1-0.4
Total zone transitions, hab. session 20.60.84.7-0.6-0.21.40.90.30.90.6-0.40.32.2-0.40.40.6-1.50.5-0.5
Total locomotion distance, hab. session 24.05.37.51.7-2.52.62.72.62.72.62.02.21.62.02.62.50.52.61.9
Locomotion velocity, hab. session 24.25.77.92.0-2.72.52.82.82.82.72.22.41.32.22.72.50.92.72.2
Novel to familiar place preference ratio0.60.71.10.9-0.90.50.80.90.80.91.01.0-0.10.90.90.20.70.91.0
Novelty place preference0.40.40.70.6-0.70.20.50.80.50.60.80.8-0.30.80.7-0.10.80.70.8
Time in novel zone, NPP test0.40.40.70.6-0.70.30.60.80.60.70.80.8-0.20.70.7-0.10.70.70.8
Total zone transitions, NPP test0.20.31.30.0-0.30.80.60.20.60.5-0.00.41.1-0.00.40.3-0.70.40.0
Total locomotion distance, NPP test4.46.28.62.2-2.72.82.92.62.92.92.12.71.82.22.82.60.52.82.2
Locomotion velocity, NPP test3.75.37.22.1-2.52.52.72.42.62.72.12.61.42.12.62.40.72.62.1
Pavlov. Cond. lever latency0.81.11.7-1.11.2-0.7-1.0-1.3-1.0-1.1-1.2-0.90.3-1.2-1.2-0.4-1.0-1.1-1.2
Pavlov. Cond. magazine entry latency0.70.91.40.8-1.01.21.11.01.21.10.80.70.60.81.11.00.11.10.8
Pavlov. Cond. change in total contacts0.50.60.90.7-0.80.90.90.80.90.90.70.90.40.70.90.50.20.90.7
Pavlov. Cond. index score0.50.60.90.7-0.90.70.80.90.90.80.80.6-0.00.80.90.60.50.90.8
Pavlov. Cond. latency score0.91.21.71.1-1.30.91.11.31.11.11.20.9-0.21.21.20.80.91.21.2
Pavlov. Cond. lever contacts0.60.71.00.8-1.00.80.91.01.01.00.90.80.10.91.00.60.51.00.9
Pavlov. Cond. magazine entry number0.10.20.70.5-0.3-0.30.00.30.00.10.50.5-0.70.50.2-0.10.80.20.5
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.30.20.20.0-0.50.0-0.1-0.3-0.10.6-0.4-0.1-0.3-0.6-0.1-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.30.50.5-0.70.50.60.70.60.60.60.4-0.00.60.70.30.40.60.6
Pavlov. Cond. response bias0.20.20.60.1-0.30.80.60.40.60.50.10.20.70.20.40.5-0.50.50.1
Bone: apparent density1.22.04.50.8-1.12.11.81.01.71.60.71.72.00.71.41.5-1.01.50.8
Bone surface0.91.73.40.7-1.11.81.61.01.61.50.61.61.60.71.31.6-0.61.40.7
Bone volume1.21.93.90.9-1.22.01.81.11.71.60.81.71.70.81.51.5-0.61.60.8
Bone: connectivity density0.71.12.30.8-0.91.51.30.71.31.20.61.21.30.71.01.4-0.61.10.7
Bone: cortical apparent density0.81.12.1-1.31.1-0.7-1.0-1.1-1.0-1.1-1.0-1.5-0.2-1.1-1.1-1.3-0.6-1.1-1.0
Bone: cortical area0.61.04.5-0.2-0.31.71.10.41.10.8-0.40.32.1-0.30.61.1-1.50.7-0.4
Bone: cortical porosity4.24.56.7-2.02.2-2.1-2.3-2.0-2.3-2.4-2.1-2.6-0.8-2.1-2.3-2.6-0.6-2.3-2.2
Bone: cortical porosity4.24.66.6-2.32.2-1.8-2.1-2.1-2.2-2.3-2.3-2.6-0.3-2.3-2.3-2.4-1.2-2.3-2.4
Bone: cortical thickness0.10.20.7-0.60.20.50.1-0.10.2-0.1-0.6-0.80.8-0.6-0.10.0-0.8-0.1-0.6
Bone: cortical thickness0.20.30.5-0.70.5-0.1-0.3-0.5-0.3-0.4-0.7-0.70.3-0.7-0.4-0.4-0.5-0.4-0.7
Bone: cortical tissue density0.81.12.0-1.21.0-0.8-1.0-1.1-1.0-1.1-1.0-1.4-0.3-1.0-1.1-1.3-0.5-1.1-0.9
Bone: elastic displacement2.12.43.4-1.61.7-1.3-1.6-1.8-1.7-1.7-1.7-1.6-0.1-1.6-1.8-1.4-1.1-1.8-1.6
Bone: elastic work0.81.01.3-1.11.1-0.8-1.0-1.2-1.0-1.1-1.1-1.10.0-1.1-1.1-0.6-0.8-1.1-1.1
Bone: endosteal estimation0.61.33.20.4-0.71.61.40.71.31.20.41.61.80.41.01.6-0.81.20.4
Bone: endosteal perimeter1.02.05.40.5-0.92.21.80.81.71.50.31.62.30.41.31.9-1.31.50.3
Bone: final force0.91.46.3-0.2-0.62.01.50.51.41.1-0.20.62.5-0.20.91.1-1.51.0-0.3
Bone: final moment0.71.15.3-0.3-0.51.81.30.41.31.0-0.30.62.3-0.30.81.0-1.40.9-0.3
Bone: marrow area0.71.43.10.5-0.81.61.50.81.41.30.41.71.80.51.11.6-0.71.30.5
Bone: maximum diameter1.42.58.70.2-1.02.62.01.01.91.60.01.23.00.11.32.0-1.71.5-0.0
Bone: maximum force0.40.61.40.3-0.71.21.10.81.10.90.30.81.10.30.80.9-0.30.90.3
Bone: maximum moment0.30.50.90.2-0.60.90.90.80.90.80.30.80.80.30.70.8-0.10.80.3
Bone: minimum diameter0.30.52.5-0.2-0.21.20.80.30.80.6-0.30.31.6-0.30.40.9-1.00.5-0.3
Bone: periosteal estimation0.81.56.10.0-0.62.01.50.61.41.2-0.11.02.5-0.10.91.6-1.51.1-0.1
Bone: periosteal perimeter0.91.54.50.1-0.82.01.60.81.61.30.11.22.10.11.11.4-1.21.20.0
Bone: post-yield work0.20.31.10.4-0.4-0.4-0.00.60.00.20.70.7-1.00.60.30.31.10.30.6
Bone: stiffness0.71.12.60.3-1.01.61.41.11.51.30.50.91.40.41.21.0-0.31.20.4
Bone: tissue strength0.60.61.40.6-0.90.80.90.90.90.90.60.70.50.60.91.20.20.80.6
Bone: trabecular number1.32.05.40.7-1.02.21.80.91.71.50.51.62.30.61.31.6-1.31.40.6
Bone: trabecular spacing0.20.30.9-0.30.2-0.8-0.6-0.1-0.5-0.5-0.2-0.9-1.0-0.2-0.4-0.40.8-0.4-0.3
Bone: trabecular thickness0.30.40.90.6-0.51.00.80.30.80.70.40.50.90.40.60.2-0.50.60.5
Bone: trabecular tissue density0.70.92.30.2-0.91.51.31.01.31.20.50.91.10.51.10.5-0.31.10.5
Breakpoint value in progressive ratio session0.60.61.9-1.10.70.1-0.3-0.8-0.3-0.5-1.1-0.71.0-1.1-0.6-0.4-1.4-0.6-1.1
Distance traveled before self-admin3.13.37.50.8-1.52.72.31.32.32.10.82.22.60.81.81.9-1.12.00.8
Distance traveled after self-admin0.80.94.3-0.2-0.31.61.10.21.00.8-0.20.82.1-0.10.60.6-1.40.7-0.2
Delta time in closed arm before/after self-admin0.10.10.30.00.1-0.4-0.3-0.0-0.3-0.30.0-0.1-0.5-0.0-0.2-0.50.5-0.20.0
Delta time in open arm before/after self-admin0.90.92.00.5-0.81.41.20.81.21.10.51.01.20.60.91.1-0.51.00.5
Diff in mean of infusions in LGA sessions0.50.61.5-0.30.7-1.2-1.0-0.6-1.0-0.9-0.3-0.6-1.2-0.3-0.8-0.80.4-0.8-0.3
Extinction: sum of active levers before priming0.30.30.5-0.60.6-0.4-0.5-0.5-0.5-0.6-0.6-0.70.1-0.6-0.6-0.3-0.4-0.6-0.6
Active lever presses in extinction session 60.40.41.10.8-0.80.10.40.60.40.60.81.1-0.30.70.60.40.80.50.8
Delta distance traveled before/after self-admin0.91.01.4-1.01.0-0.9-1.0-1.1-1.1-1.1-1.0-1.2-0.2-0.9-1.1-1.2-0.4-1.1-1.0
Delta ambulatory time before/after self-admin2.22.44.5-0.91.4-2.1-1.9-1.4-1.9-1.8-0.9-2.0-1.7-0.8-1.6-1.90.6-1.7-0.9
Time in closed arm before self-admin0.20.20.7-0.10.3-0.7-0.6-0.2-0.5-0.5-0.1-0.5-0.80.0-0.4-0.20.4-0.4-0.1
Time in closed arm after self-admin1.61.72.8-0.91.3-1.7-1.6-1.1-1.5-1.5-0.9-1.5-1.3-1.0-1.3-1.60.3-1.4-0.9
Time in open arm before self-admin0.20.20.3-0.40.5-0.5-0.5-0.4-0.5-0.5-0.4-0.5-0.3-0.5-0.5-0.4-0.1-0.5-0.4
Time in open arm after self-admin1.92.13.21.3-1.51.61.71.51.71.71.31.70.91.31.61.80.21.61.3
Sum of active levers in priming session hrs 5-60.70.71.00.8-0.91.01.00.81.01.00.80.80.60.71.00.80.11.00.8
Time to tail flick, vehicle, before self-admin2.22.33.71.7-1.60.71.31.71.21.51.71.9-0.21.71.51.81.31.51.7
Time to tail flick, vehicle, after self-admin0.10.10.4-0.40.4-0.2-0.3-0.5-0.3-0.3-0.4-0.00.1-0.4-0.4-0.6-0.4-0.3-0.4
Time to tail flick, test, before self-admin0.60.61.7-1.00.7-0.1-0.4-0.7-0.5-0.6-1.0-1.30.7-1.0-0.7-0.6-1.0-0.6-1.0
Time to tail flick, test, after self-admin1.31.32.91.5-1.20.10.61.20.70.91.50.6-1.11.51.01.11.70.91.5
Delta time to tail flick, vehicle, before/after SA0.70.72.1-1.10.80.3-0.2-0.9-0.2-0.4-1.1-0.61.1-1.1-0.6-0.9-1.4-0.5-1.1
Delta time to tail flick, test, before/after SA2.62.33.51.8-1.50.61.11.61.21.41.81.9-0.81.81.51.51.71.41.8
Ambulatory time before self-admin1.21.35.2-0.0-0.61.81.40.41.31.1-0.01.32.3-0.00.91.0-1.51.0-0.0
Ambulatory time after self-admin0.40.52.0-0.90.40.60.1-0.60.1-0.1-0.9-0.11.4-0.8-0.3-0.2-1.4-0.2-0.9
Total heroin consumption0.40.51.80.1-0.61.20.90.50.90.70.10.11.30.20.70.9-0.80.60.1
Area under the delay curve0.10.10.5-0.30.2-0.6-0.4-0.2-0.4-0.4-0.1-0.2-0.5-0.2-0.3-0.70.4-0.4-0.1
Delay disc. indifference point, 0s delay1.51.66.0-0.30.7-2.2-1.6-0.6-1.5-1.30.1-0.8-2.4-0.0-1.0-1.61.6-1.20.2
Delay disc. indifference point, 16s delay0.10.10.50.20.1-0.5-0.3-0.0-0.3-0.20.20.1-0.70.2-0.1-0.30.5-0.20.1
Delay disc. indifference point, 2s delay0.00.00.20.1-0.1-0.2-0.00.1-0.00.00.20.1-0.10.10.1-0.40.30.00.1
Delay disc. indifference point, 24s delay0.30.21.40.10.1-0.8-0.50.2-0.5-0.40.2-0.3-1.20.3-0.20.11.0-0.30.1
Delay disc. indifference point, 4s delay0.70.72.0-1.00.8-0.7-0.8-0.8-0.8-0.8-0.9-0.8-0.1-0.9-0.8-1.4-0.4-0.8-0.9
Delay disc. indifference point, 8s delay0.50.51.2-0.90.8-0.8-0.8-0.6-0.8-0.8-0.7-0.4-0.4-0.7-0.8-1.1-0.2-0.7-0.8
Delay discount exponential model param0.20.20.60.4-0.30.60.50.30.50.50.20.30.50.30.40.8-0.30.40.3
Delay discount hyperbolic model param0.20.20.80.4-0.30.60.50.30.50.40.20.30.50.30.40.9-0.30.40.3
Fecal boli incidents, locomotor time 10.50.61.0-1.00.9-0.6-0.8-0.6-0.7-0.9-0.8-0.9-0.2-0.8-0.8-0.7-0.5-0.8-0.9
Change in fecal boli incidents, locomotor task0.00.00.00.0-0.1-0.1-0.0-0.1-0.00.00.10.0-0.20.10.0-0.20.2-0.00.2
Time >=10cm from walls, locomotor time 10.90.92.1-1.51.0-0.3-0.7-0.9-0.7-0.8-1.2-0.90.5-1.3-0.9-0.9-1.1-0.8-1.2
Bouts of movement, locomotor time 11.92.17.0-0.40.9-2.3-1.9-1.1-1.8-1.6-0.2-1.6-2.6-0.1-1.3-1.31.5-1.50.1
Total resting periods, locomotor time 12.22.46.1-0.71.2-2.4-2.0-1.2-2.0-1.8-0.5-1.9-2.5-0.4-1.5-1.41.2-1.7-0.3
Rest time, locomotor task time 10.50.61.1-0.50.7-1.0-1.0-0.7-0.9-0.9-0.5-0.8-0.8-0.5-0.8-0.80.2-0.9-0.5
Distance moved, locomotor task time 10.00.00.1-0.1-0.10.20.20.30.20.10.20.10.10.10.2-0.30.00.20.2
Vertical activity count, locomotor time 10.20.20.40.0-0.40.60.60.50.60.60.30.50.50.20.50.2-0.10.60.3
Time >=10cm from walls, locomotor time 20.10.10.4-0.20.20.20.1-0.3-0.00.0-0.10.40.6-0.2-0.1-0.2-0.6-0.00.0
Bouts of movement, locomotor time 21.81.92.9-1.11.5-1.5-1.6-1.6-1.6-1.6-1.2-1.7-0.9-1.1-1.5-1.6-0.3-1.6-1.1
Total resting periods, locomotor time 22.62.74.1-1.51.8-1.7-1.9-1.9-1.9-1.9-1.5-2.0-0.8-1.5-1.8-1.9-0.6-1.9-1.5
Rest time, locomotor task time 21.72.03.2-1.51.3-1.4-1.5-1.3-1.5-1.6-1.4-1.8-0.8-1.4-1.5-1.5-0.3-1.6-1.5
Distance moved, locomotor task time 21.41.62.71.5-1.40.81.21.31.21.31.61.5-0.11.51.30.81.01.31.7
Vertical activity count, locomotor time 21.82.03.01.6-1.51.21.51.51.41.51.51.70.41.51.51.20.71.51.6
Weight adjusted by age3.43.88.00.9-1.72.82.51.72.42.31.02.12.61.02.02.4-0.92.10.9
Seeking ratio, delayed vs. immediate footshock0.00.10.30.4-0.2-0.2-0.10.0-0.10.00.2-0.0-0.40.20.10.10.50.00.3
Locomotion in novel chamber0.10.20.7-0.40.20.40.2-0.30.10.1-0.40.20.8-0.4-0.10.2-0.80.0-0.4
Locomotion in novel chamber post-restriction0.60.82.0-1.20.80.2-0.2-0.9-0.3-0.5-1.2-0.71.2-1.2-0.6-0.4-1.4-0.5-1.2
Progressive ratio1.31.57.50.00.3-2.1-1.4-0.2-1.4-1.00.3-0.4-2.70.3-0.7-1.12.0-0.90.2
Food seeking constrained by brief footshock2.93.54.51.9-2.11.82.11.92.02.11.91.90.71.92.11.91.02.11.9
Seeking ratio, punishment vs. effort2.53.17.61.0-1.42.82.31.22.22.00.81.32.70.81.72.0-1.21.90.9
Run reversals in cocaine runway, females0.90.91.70.4-0.71.31.20.81.11.10.51.21.30.50.91.2-0.51.00.5
Run reversals in cocaine runway, males0.40.31.5-0.3-0.31.00.7-0.10.70.6-0.30.01.2-0.30.40.5-0.70.4-0.3
Latency to leave start box in cocaine runway0.40.51.9-0.20.3-1.1-0.8-0.2-0.8-0.7-0.0-0.2-1.4-0.1-0.5-0.71.0-0.6-0.1
Latency to leave start box in cocaine runway, F1.41.53.7-0.70.9-1.9-1.6-0.7-1.5-1.4-0.5-1.3-1.9-0.5-1.2-1.31.0-1.3-0.6
Latency to leave start box in cocaine runway, M1.41.33.51.2-1.20.91.11.11.11.21.21.90.21.11.21.00.61.21.2
Cd content in liver0.10.10.3-0.2-0.20.40.3-0.00.30.20.0-0.00.5-0.00.20.1-0.40.2-0.1
Co content in liver0.20.31.3-0.2-0.20.90.60.20.60.5-0.10.21.1-0.10.40.3-0.70.4-0.1
Cu content in liver0.40.42.1-0.80.30.60.2-0.30.2-0.0-0.7-0.41.5-0.7-0.20.0-1.3-0.1-0.7
Fe content in liver0.40.50.90.7-0.60.80.80.60.80.80.50.80.70.50.70.9-0.10.80.5
K content in liver0.00.00.30.0-0.10.10.1-0.00.0-0.0-0.2-0.20.5-0.1-0.00.1-0.2-0.1-0.1
Mg content in liver0.20.21.60.0-0.20.80.50.10.50.3-0.20.01.3-0.10.30.4-0.70.3-0.1
Mn content in liver0.30.31.9-0.60.10.70.3-0.20.30.1-0.6-0.21.4-0.5-0.00.3-1.20.0-0.6
Na content in liver0.40.40.90.9-0.70.20.50.60.50.60.70.8-0.10.80.60.60.70.60.8
Rb content in liver0.70.93.7-0.0-0.51.61.20.41.10.9-0.10.71.9-0.00.70.9-1.30.8-0.0
Se content in liver1.51.83.70.9-1.21.91.71.11.71.50.81.21.80.81.41.7-0.61.50.8
Sr content in liver0.30.31.4-0.40.20.70.4-0.00.40.3-0.40.61.2-0.40.10.3-1.00.3-0.4
Zn content in liver0.70.81.21.0-1.10.91.00.91.01.01.00.70.30.91.00.50.50.91.0