Hub : Genes

Ephx2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017286 0.91 0.06 0.0e+00 0.47 0.47 0.48 0.48 3.2e-58 8.7e-59 2.9e-60 1.8e-60
2 Adipose mRNA stability ENSRNOG00000017286 0.84 0.07 0.0e+00 0.45 0.52 0.52 0.52 9.0e-55 6.8e-68 4.9e-67 5.7e-67
3 BLA gene expression ENSRNOG00000017286 0.79 0.07 0.0e+00 0.5 0.62 0.62 0.59 2.3e-30 1.1e-41 1.1e-41 1.6e-38
4 BLA mRNA stability ENSRNOG00000017286 0.33 0.13 1.2e-12 0.14 0.17 0.19 0.19 6.5e-08 1.2e-09 1.5e-10 1.2e-10
5 Brain gene expression ENSRNOG00000017286 0.78 0.08 0.0e+00 0.54 0.71 0.69 0.7 2.9e-59 1.3e-92 1.1e-88 9.7e-91
6 Brain intron excision ratio chr15:40316577:40327469 0.14 0.07 8.5e-15 0.17 0.16 0.17 0.16 3.3e-15 8.8e-15 8.0e-16 1.0e-14
7 Brain intron excision ratio chr15:40320857:40327469 0.08 0.05 1.5e-06 0.06 0.05 0.05 0.05 7.8e-06 9.7e-06 3.1e-05 2.8e-05
8 Brain mRNA stability ENSRNOG00000017286 0.48 0.11 0.0e+00 0.43 0.49 0.47 0.48 3.7e-43 2.3e-51 4.1e-49 1.1e-50
9 Eye gene expression ENSRNOG00000017286 0.67 0.13 1.5e-05 0.17 0.09 0.16 0.12 1.6e-03 1.7e-02 2.0e-03 6.2e-03
10 IL gene expression ENSRNOG00000017286 0.77 0.09 5.6e-17 0.27 0.35 0.31 0.32 3.5e-07 3.2e-09 3.8e-08 2.0e-08
11 IL mRNA stability ENSRNOG00000017286 0.67 0.13 3.1e-11 0.24 0.24 0.22 0.23 1.5e-06 2.1e-06 4.0e-06 3.6e-06
12 LHb gene expression ENSRNOG00000017286 0.88 0.06 0.0e+00 0.48 0.5 0.44 0.49 4.4e-13 1.5e-13 8.8e-12 2.8e-13
13 LHb mRNA stability ENSRNOG00000017286 0.56 0.16 4.4e-09 0.29 0.26 0.2 0.26 1.4e-07 5.6e-07 1.6e-05 6.2e-07
14 Liver gene expression ENSRNOG00000017286 0.74 0.1 0.0e+00 0.31 0.53 0.53 0.53 2.4e-35 8.7e-69 8.4e-69 1.1e-68
15 Liver mRNA stability ENSRNOG00000017286 0.59 0.17 0.0e+00 0.3 0.3 0.3 0.3 4.8e-34 1.2e-33 3.0e-33 3.0e-33
16 NAcc gene expression ENSRNOG00000017286 0.77 0.06 0.0e+00 0.61 0.7 0.69 0.7 8.6e-57 1.6e-71 7.6e-71 1.2e-72
17 NAcc intron excision ratio chr15:40316577:40327469 0.11 0.08 1.6e-05 0.04 0.06 0.04 0.04 9.9e-04 6.4e-05 5.3e-04 4.9e-04
18 NAcc mRNA stability ENSRNOG00000017286 0.28 0.1 0.0e+00 0.21 0.25 0.23 0.23 2.7e-15 1.1e-18 1.8e-17 3.6e-17
19 OFC gene expression ENSRNOG00000017286 0.79 0.1 1.1e-16 0.31 0.4 0.44 0.4 4.2e-08 1.8e-10 1.3e-11 2.0e-10
20 PL gene expression ENSRNOG00000017286 0.71 0.09 0.0e+00 0.56 0.62 0.64 0.64 1.8e-50 6.1e-60 2.8e-62 3.9e-62
21 PL mRNA stability ENSRNOG00000017286 0.28 0.11 0.0e+00 0.2 0.24 0.22 0.23 4.0e-15 6.6e-18 5.3e-17 1.5e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
BMI with tail0.20.62.1-0.9-0.3-0.5-1.3-0.2-1.31.4-0.4-0.8-0.5-0.8-0.5-0.70.1-1.0-0.7-1.4-0.5-0.2-0.5-0.4
BMI without tail1.02.02.7-1.6-1.6-1.5-1.2-1.60.4-0.1-1.6-1.5-1.4-1.5-1.5-1.5-1.5-1.7-1.50.4-1.6-1.6-1.5-1.6
Body weight0.21.01.61.11.11.10.71.1-0.7-0.11.01.11.21.11.11.01.20.90.9-0.51.11.31.01.1
Epididymis fat weight0.30.72.0-0.5-0.9-0.70.3-1.11.2-1.3-0.8-0.4-0.6-0.2-0.7-0.4-1.3-0.4-0.61.4-0.8-0.9-0.8-0.8
Glucose1.32.03.7-1.9-1.3-1.4-1.7-1.1-1.11.0-1.5-1.8-1.2-1.7-1.3-1.6-0.7-1.9-1.5-1.2-1.5-1.1-1.5-1.5
Heart weight0.10.21.20.40.20.40.70.2-0.0-1.10.10.40.60.40.50.40.40.40.30.20.20.50.20.2
Left kidney weight0.71.94.21.21.41.61.01.5-1.6-0.71.11.21.91.11.71.02.11.11.0-1.11.22.01.31.3
Right kidney weight1.54.47.92.51.82.32.81.60.3-2.81.72.42.52.42.32.11.72.31.91.11.82.22.01.9
Tail length0.31.06.61.00.20.61.7-0.11.5-2.60.21.10.71.00.60.6-0.21.00.51.80.30.20.40.3
Length with tail1.03.65.62.41.82.02.31.60.5-1.71.82.32.12.32.02.01.52.31.90.81.91.81.81.9
Length without tail2.35.18.02.32.52.41.42.7-1.40.52.52.22.32.22.42.32.72.32.2-1.32.52.82.42.5
Liver weight, left0.91.58.3-0.00.90.8-0.61.3-2.91.40.5-0.31.00.20.90.31.9-0.30.5-2.70.61.30.70.6
Liver weight, right0.40.73.7-0.20.60.4-0.70.9-1.81.40.4-0.40.5-0.10.50.11.3-0.50.4-1.90.30.80.40.4
Parametrial fat weight1.53.07.1-1.3-1.9-1.8-0.5-2.22.3-1.2-1.7-1.2-1.8-1.3-1.8-1.0-2.7-1.2-1.42.3-1.7-2.3-1.7-1.7
Retroperitoneal fat weight0.51.63.0-1.3-1.5-1.4-0.7-1.60.9-0.3-1.4-1.2-1.4-1.1-1.4-1.0-1.7-1.2-1.30.8-1.4-1.4-1.5-1.4
Intraocular pressure0.20.32.60.2-0.2-0.10.4-0.41.6-0.8-0.00.1-0.20.2-0.20.2-0.60.10.21.5-0.1-0.50.0-0.1
Extensor digitorum longus weight2.710.836.01.53.32.6-1.14.1-5.25.33.01.52.21.42.51.44.81.42.0-6.03.04.22.53.0
Soleus weight0.20.53.7-0.50.0-0.2-1.10.3-1.21.90.0-0.4-0.4-0.4-0.3-0.40.3-0.4-0.3-1.5-0.00.1-0.2-0.1
Tibialis anterior weight2.27.720.61.63.02.4-0.43.6-4.03.72.81.52.21.42.41.54.11.52.0-4.52.73.52.42.7
Tibia length2.57.015.63.12.22.73.71.81.5-4.02.22.93.03.02.73.01.62.92.72.32.31.82.62.3
Number of licking bursts0.80.91.2-1.1-1.0-1.1-1.0-0.9-0.00.7-1.0-1.1-1.1-1.1-1.1-1.1-0.9-1.1-1.0-0.2-1.0-0.9-1.1-1.0
Food consumed during 24 hour testing period1.11.32.90.91.11.31.41.0-0.3-1.70.80.91.71.11.51.11.30.91.10.00.91.41.11.0
Times rat made contact with spout0.20.20.5-0.6-0.5-0.4-0.2-0.6-0.2-0.6-0.7-0.7-0.2-0.5-0.4-0.5-0.3-0.7-0.50.1-0.7-0.4-0.5-0.6
Mean time between licks in bursts0.91.36.4-0.2-0.9-0.80.5-1.32.5-1.6-0.7-0.1-0.9-0.2-0.9-0.2-1.7-0.1-0.42.5-0.8-1.2-0.7-0.7
Mean num. licks in bursts0.30.41.00.60.50.70.80.5-0.3-1.00.40.50.80.60.70.60.60.50.60.20.40.60.60.5
Std. dev. time between licks in bursts2.32.710.61.70.81.02.30.33.3-2.61.11.70.91.70.81.7-0.41.71.53.21.00.21.11.0
Water consumed over 24 hours0.60.81.60.51.11.00.51.1-0.10.21.00.61.00.81.00.81.30.60.9-0.70.91.20.91.0
Indifference point 0 sec4.57.315.03.22.22.63.81.72.0-3.92.33.12.73.02.63.11.23.02.92.82.31.72.62.3
Indifference point AUC1.72.05.3-1.7-0.8-1.1-2.1-0.6-1.72.3-1.0-1.5-1.2-1.5-1.2-1.7-0.3-1.4-1.4-2.1-1.0-0.6-1.3-1.0
Indifference point function ln k1.31.83.41.61.11.31.90.91.0-1.71.21.41.41.51.31.70.71.31.71.21.21.01.31.2
Indifference point function log k1.31.83.41.61.11.31.90.91.0-1.71.21.41.41.51.31.70.71.31.71.21.21.01.31.2
Delay discounting total patch changes 0 sec4.67.514.13.32.32.73.81.91.7-3.72.33.12.93.12.73.11.43.13.02.62.41.92.72.4
Delay discounting total patch changes 12 sec0.71.01.81.20.91.01.30.70.6-1.20.91.31.01.11.01.00.51.31.00.80.90.61.00.9
Delay discounting total patch changes 18 sec0.10.11.20.3-0.10.10.6-0.20.6-1.1-0.10.30.20.20.10.0-0.20.40.10.7-0.1-0.0-0.0-0.0
Delay discounting total patch changes 24 sec2.43.04.52.11.71.82.11.50.5-1.61.72.01.92.01.91.91.32.12.00.91.71.41.81.7
Delay discounting total patch changes 6 sec0.20.30.80.70.30.50.80.20.3-0.90.30.70.50.70.50.50.10.80.40.50.40.30.30.4
Delay discounting time to switch 0 sec0.20.31.90.1-0.4-0.30.3-0.51.4-0.6-0.20.2-0.4-0.0-0.3-0.1-0.80.2-0.21.2-0.2-0.7-0.2-0.3
Delay discounting water rate 0 sec0.60.91.60.91.11.10.71.1-0.7-0.11.00.91.01.01.01.01.10.81.0-0.41.01.31.01.0
Delay discounting water rate 12 sec0.91.31.81.21.21.21.01.2-0.3-0.41.21.11.31.21.31.31.31.11.3-0.21.21.21.21.2
Delay discounting water rate 18 sec1.01.45.70.51.11.1-0.01.4-2.40.90.90.41.20.61.10.51.80.30.7-2.10.91.80.90.9
Delay discounting water rate 24 sec0.40.61.0-1.0-0.7-0.7-0.9-0.5-0.90.6-0.8-0.9-0.5-0.9-0.6-0.8-0.2-1.0-0.7-0.9-0.8-0.1-0.8-0.7
Delay discounting water rate 6 sec2.13.05.01.72.01.91.12.1-1.1-0.01.81.62.01.71.91.72.21.61.8-1.01.82.21.81.9
Locomotor activity7.211.516.84.13.53.73.53.30.1-1.93.54.03.73.83.73.73.13.93.50.53.63.43.73.6
Locomotor testing distance5.89.715.74.02.83.13.92.41.9-3.23.03.83.13.63.03.61.73.83.32.53.12.23.23.0
Locomotor testing rearing8.012.620.04.53.13.44.52.62.7-3.83.44.13.44.13.44.11.94.23.93.33.42.23.73.4
Light reinforcement 10.81.52.4-1.3-1.3-1.1-0.3-1.51.2-1.4-1.4-1.2-0.9-1.3-1.1-0.8-1.5-1.3-0.81.4-1.4-1.5-1.1-1.4
Light reinforcement 23.44.57.1-2.7-2.2-2.2-2.1-2.1-0.10.8-2.3-2.4-2.1-2.5-2.2-2.3-1.8-2.5-2.3-0.4-2.3-1.9-2.3-2.3
Reaction time number correct0.50.71.7-1.0-0.7-0.9-1.2-0.50.21.3-0.6-1.0-1.0-1.0-0.9-0.6-0.6-1.0-0.7-0.5-0.6-0.8-0.8-0.7
Reaction time mean minus median0.50.61.01.00.80.80.80.80.2-0.20.90.90.71.00.80.80.71.00.90.20.90.80.90.9
Reaction time mean minus median AUC0.10.20.30.50.40.40.40.40.1-0.10.50.50.40.50.40.50.30.50.50.20.50.40.50.5
Reaction time num false alarms0.30.40.80.80.60.70.90.50.5-0.60.70.60.60.70.70.90.30.60.90.70.70.40.80.6
Reaction time num false alarms AUC0.30.40.70.70.60.70.80.60.0-0.60.60.50.80.60.80.80.50.60.80.20.70.60.80.6
Reaction time trials correct on left0.50.71.7-1.0-0.7-0.9-1.2-0.50.21.3-0.6-1.0-1.0-1.0-0.9-0.6-0.6-1.0-0.7-0.5-0.6-0.8-0.8-0.7
Reaction time trials on left0.50.81.6-1.0-0.8-1.0-1.2-0.60.31.2-0.7-1.0-1.1-1.0-1.0-0.7-0.7-1.1-0.7-0.4-0.7-0.9-0.8-0.8
Reaction time mean0.10.10.30.40.40.40.20.4-0.30.20.40.50.30.50.30.30.40.50.2-0.20.40.60.40.4
Reaction time mean AUC0.30.40.70.70.70.70.40.7-0.20.20.70.80.60.80.60.70.70.80.6-0.20.70.80.70.7
Median of all reaction times0.00.00.20.10.10.1-0.00.2-0.30.30.10.20.10.20.10.10.30.2-0.1-0.40.10.40.10.2
Reaction time omissions0.40.62.4-0.2-0.8-0.70.2-0.91.4-0.8-0.6-0.3-0.6-0.1-0.6-0.2-1.2-0.2-0.51.6-0.6-0.9-0.5-0.6
Reaction time false alarm rate0.30.41.00.70.60.71.00.5-0.1-1.00.50.60.80.60.80.70.50.70.70.40.60.60.70.6
Reaction time premature initiation rate0.10.10.7-0.10.20.1-0.40.3-0.80.80.2-0.1-0.0-0.2-0.0-0.20.4-0.20.1-0.80.10.50.10.1
Reaction time premature initiations0.30.42.5-0.7-0.2-0.4-1.1-0.0-0.61.6-0.2-0.7-0.6-0.7-0.5-0.60.0-0.8-0.3-1.1-0.3-0.0-0.4-0.3
Std. dev. reaction times0.10.10.40.50.30.30.30.3-0.20.10.30.50.30.50.30.10.30.50.2-0.10.30.60.30.4
Reaction time trials completed0.50.81.6-1.0-0.8-1.0-1.2-0.60.31.2-0.7-1.0-1.1-1.0-1.0-0.7-0.7-1.1-0.7-0.4-0.7-0.9-0.8-0.8
Reaction time trials AUC0.50.71.4-1.0-0.7-0.9-1.2-0.60.31.2-0.6-0.9-1.0-0.9-0.9-0.6-0.7-1.0-0.7-0.4-0.7-0.8-0.8-0.7
Social response proportion3.33.65.1-2.3-1.9-2.1-2.0-1.80.01.3-1.9-2.3-2.2-2.1-2.1-2.1-1.8-2.1-1.8-0.3-2.0-1.8-2.0-2.0
Social responses1.92.55.9-1.3-1.6-1.5-0.4-1.92.4-1.1-1.4-1.5-1.6-1.2-1.6-0.9-2.2-1.4-0.82.3-1.5-2.1-1.3-1.6
Social time0.81.02.91.30.81.01.50.60.7-1.70.81.11.11.01.01.10.41.11.01.20.80.41.00.8
Conditioned locomotion0.91.12.0-1.2-1.1-1.2-1.2-1.00.31.0-0.9-0.9-1.4-1.2-1.3-1.1-1.2-1.0-1.00.1-1.0-1.1-1.1-1.0
Cocaine response after cond. corrected3.53.96.6-2.3-1.8-2.1-2.6-1.6-0.52.5-1.8-2.2-2.3-2.2-2.1-2.2-1.4-2.2-2.0-1.2-1.8-1.7-2.0-1.9
Cocaine response after cond. not corrected2.02.23.7-1.7-1.4-1.6-1.9-1.2-0.31.9-1.3-1.6-1.8-1.6-1.7-1.6-1.2-1.6-1.5-0.8-1.3-1.3-1.5-1.4
Cocaine response before conditioning1.92.44.41.91.31.52.11.00.7-2.01.31.91.61.81.51.70.71.91.51.41.41.11.51.4
Saline control response0.81.01.81.20.91.01.40.80.5-1.30.91.01.21.11.11.20.71.11.10.80.90.61.10.9
Condit. Reinf. active minus inactive responses0.10.10.80.40.20.20.40.00.7-0.50.30.20.10.30.10.4-0.20.30.30.90.2-0.30.30.2
Condit. Reinf. active-inactive response ratio0.20.20.7-0.5-0.2-0.3-0.8-0.2-0.60.8-0.3-0.6-0.4-0.6-0.4-0.5-0.1-0.6-0.4-0.5-0.3-0.3-0.3-0.3
Condit. Reinf. active responses0.20.31.70.4-0.00.10.7-0.21.1-1.10.10.30.10.20.00.3-0.40.30.31.30.0-0.30.10.0
Condit. Reinf. inactive responses0.60.74.40.5-0.2-0.01.1-0.52.0-1.8-0.10.6-0.00.4-0.10.3-0.90.60.22.1-0.1-0.50.0-0.1
Condit. Reinf. lever presses1.72.33.61.81.51.61.91.30.2-1.51.41.71.81.61.71.61.31.81.60.61.51.31.61.5
Condit. Reinf. lever reinforcers received0.20.21.10.50.20.30.70.00.8-1.00.20.40.30.30.30.4-0.10.40.41.10.2-0.10.30.2
Pavlov. Cond. lever latency2.02.84.3-1.8-1.8-1.9-1.5-1.81.00.5-1.6-1.7-2.0-1.6-2.0-1.5-2.0-1.8-1.70.7-1.7-2.1-1.8-1.8
Pavlov. Cond. magazine entry latency1.21.42.21.31.11.31.41.0-0.1-1.31.01.21.51.21.41.11.21.31.20.21.01.31.21.1
Pavlov. Cond. change in total contacts2.53.46.21.82.12.01.32.2-1.30.01.91.62.21.72.11.62.51.71.9-1.31.92.42.02.0
Pavlov. Cond. index score2.53.34.82.01.92.01.81.9-0.7-0.81.81.92.21.82.11.72.12.01.9-0.41.92.21.91.9
Pavlov. Cond. latency score2.73.44.72.11.92.11.91.9-0.4-1.11.82.02.21.92.11.82.02.01.9-0.11.92.11.91.9
Pavlov. Cond. lever contacts3.24.46.12.42.22.32.12.2-0.7-0.92.12.22.52.12.42.02.32.32.2-0.32.22.52.22.2
Pavlov. Cond. magazine entry number1.01.22.1-1.2-1.0-1.2-1.5-0.9-0.31.3-0.9-1.2-1.3-1.2-1.2-1.1-1.0-1.2-1.1-0.5-1.0-1.1-1.1-1.0
Pavlov. Cond. intertrial magazine entries1.82.39.6-0.5-1.4-1.20.4-1.82.8-2.1-1.1-0.5-1.2-0.4-1.3-0.3-2.4-0.5-0.83.1-1.2-2.2-1.0-1.2
Pavlov. Cond. lever-magazine prob. diff.2.22.94.41.91.81.91.61.8-0.8-0.61.71.72.01.72.01.62.01.81.7-0.51.72.11.81.8
Pavlov. Cond. response bias3.54.86.52.42.32.42.12.3-0.6-1.02.22.32.62.22.52.12.52.42.3-0.32.32.52.32.3
Conditioned reinforcement - actives1.01.01.9-0.8-1.2-1.0-0.3-1.30.7-0.8-1.1-0.7-0.9-0.6-1.0-0.9-1.4-0.7-1.20.9-1.1-1.0-1.1-1.1
Conditioned reinforcement - inactives0.60.64.30.6-0.00.31.3-0.31.3-2.1-0.00.90.40.80.2-0.0-0.60.60.01.70.0-0.10.10.1
Conditioned locomotion0.40.51.1-0.7-0.8-0.6-0.2-0.90.4-0.5-0.8-0.4-0.6-0.4-0.7-0.8-1.0-0.5-1.10.4-0.8-0.6-0.9-0.7
Intermittent access intake day 1-15 change0.10.10.6-0.1-0.2-0.10.1-0.30.5-0.8-0.2-0.2-0.1-0.2-0.2-0.4-0.3-0.2-0.00.6-0.2-0.5-0.1-0.2
Intermittent access intake escalation0.10.10.2-0.2-0.1-0.1-0.1-0.20.2-0.3-0.1-0.3-0.1-0.3-0.2-0.4-0.2-0.3-0.00.3-0.2-0.4-0.1-0.2
Intermittent access intake escalation 20.00.00.10.00.10.10.00.10.2-0.30.1-0.10.1-0.10.1-0.10.0-0.10.20.20.0-0.20.20.0
Intermitt. access day 1 inactive lever presses0.50.61.1-0.8-0.8-0.8-0.6-0.80.90.3-0.6-0.6-0.9-0.6-0.9-0.7-1.0-0.6-0.80.4-0.7-0.9-0.8-0.7
Intermitt. access day 15 inactive lever presses0.00.00.1-0.10.20.20.10.2-0.2-0.00.10.10.30.00.2-0.30.3-0.00.2-0.30.10.20.20.2
Intermitt. access escalation Index0.10.00.2-0.1-0.1-0.2-0.3-0.1-0.10.5-0.1-0.2-0.3-0.1-0.30.1-0.1-0.2-0.3-0.2-0.1-0.3-0.1-0.1
Intermittent access day 1 total infusions0.20.20.8-0.6-0.4-0.3-0.4-0.4-0.80.0-0.6-0.3-0.2-0.4-0.3-0.70.0-0.3-0.9-0.7-0.50.3-0.7-0.4
Intermittent access day 15 total infusions0.60.71.3-1.0-0.8-0.8-0.8-0.8-0.20.1-0.9-0.9-0.7-0.9-0.8-1.1-0.6-0.9-1.1-0.3-0.9-0.6-1.0-0.9
Intermittent access terminal intake (last 3 days)0.60.71.8-0.9-0.6-0.6-1.0-0.5-1.10.6-0.8-0.9-0.5-0.9-0.6-1.3-0.1-0.9-1.1-1.0-0.8-0.3-0.8-0.7
Intermittent access total infusions1.21.32.8-1.3-1.2-1.1-1.1-1.2-0.50.3-1.3-1.1-1.1-1.1-1.2-1.5-0.9-1.1-1.7-0.5-1.3-0.7-1.5-1.2
Intermittent access day 1 locomotion0.20.21.30.2-0.10.20.8-0.20.5-1.1-0.10.60.30.60.20.2-0.30.6-0.30.6-0.10.4-0.20.0
Intermittent access day 15 total locomotion0.50.51.2-1.0-0.8-0.6-0.3-0.80.1-0.6-0.9-0.6-0.4-0.6-0.6-0.9-0.6-0.6-1.1-0.1-0.9-0.1-1.0-0.8
Intermittent access total locomotion0.10.10.7-0.1-0.20.10.4-0.30.4-0.8-0.20.40.10.3-0.0-0.1-0.30.3-0.50.3-0.20.4-0.4-0.1
Intermittent access standard deviation0.20.20.80.10.40.50.30.5-0.8-0.50.2-0.10.7-0.00.60.20.9-0.10.6-0.40.20.40.50.3
Cocaine induced anxiety2.83.25.21.91.91.91.91.80.7-0.91.92.31.92.31.91.91.62.11.70.21.91.72.02.0
Post-drug Anxiety0.60.64.60.4-0.00.11.0-0.22.1-1.40.10.50.10.60.10.5-0.70.50.41.80.2-0.40.30.1
Baseline Anxiety0.91.02.7-0.6-1.1-0.9-0.1-1.21.3-1.0-0.9-0.8-0.9-0.8-1.0-0.4-1.5-0.7-0.61.6-1.0-1.4-0.8-1.0
Lifetime Intake0.40.51.4-0.8-0.8-0.6-0.4-0.8-0.2-0.2-0.9-0.5-0.6-0.5-0.7-1.0-0.6-0.5-1.2-0.2-0.8-0.3-1.0-0.8
Incentive Sensitization - Responses0.30.32.00.30.40.70.70.3-0.8-1.40.20.30.90.40.70.20.60.50.2-0.10.20.90.30.3
Incentive Sensitization - Breakpoint0.40.42.60.40.40.70.80.3-0.6-1.60.20.40.90.50.70.30.50.60.30.10.20.80.30.3
Progressive ratio test 1 active lever presses1.91.93.2-1.8-1.3-1.3-1.7-1.1-1.11.2-1.4-1.5-1.2-1.6-1.3-1.8-0.6-1.6-1.7-1.3-1.4-0.7-1.5-1.4
Progressive ratio test 1 breakpoint2.52.64.3-2.1-1.5-1.5-1.9-1.3-1.01.3-1.7-1.9-1.4-1.9-1.5-2.0-0.8-1.9-1.8-1.3-1.6-1.0-1.7-1.6
Progressive ratio test 1 inactive lever presses0.70.71.1-1.1-0.9-0.9-0.5-1.01.0-0.3-0.9-0.9-0.8-0.9-0.9-0.8-1.0-1.0-0.70.6-0.9-1.1-0.8-0.9
Progressive ratio test 2 active lever presses1.31.42.4-1.5-1.2-1.0-1.1-1.1-1.10.1-1.4-1.4-0.8-1.3-1.0-1.5-0.6-1.2-1.5-0.9-1.3-0.5-1.4-1.2
Progressive ratio test 2 breakpoint0.70.81.6-1.1-0.9-0.7-0.8-0.8-1.2-0.4-1.1-1.0-0.4-0.9-0.6-1.2-0.3-0.9-1.2-0.8-1.1-0.2-1.1-0.9
Progressive ratio test 2 inactive lever presses0.10.20.7-0.5-0.4-0.20.1-0.4-0.1-0.8-0.5-0.2-0.0-0.2-0.2-0.8-0.3-0.1-0.7-0.0-0.50.2-0.5-0.4
Total sessions with >9 infusions0.60.71.3-0.9-0.9-0.9-0.5-0.91.10.1-0.8-0.6-1.0-0.6-1.0-0.7-1.1-0.7-0.90.5-0.8-1.0-0.9-0.8
Short access day 1 total inactive lever presses0.40.41.7-0.7-0.6-0.3-0.2-0.6-1.0-0.5-0.8-0.2-0.2-0.3-0.3-1.3-0.3-0.3-1.2-0.6-0.80.4-1.0-0.6
Short access day 10 total inactive lever presses1.01.11.7-1.3-1.1-1.1-0.8-1.11.00.2-1.0-1.0-1.1-1.1-1.1-1.2-1.1-1.2-0.80.4-1.0-1.3-1.0-1.0
Short access day 1 total infusions0.60.72.1-0.9-0.8-0.8-0.8-0.8-0.30.7-0.8-0.4-0.9-0.4-0.9-1.4-0.7-0.6-1.3-0.6-0.8-0.3-1.1-0.7
Short access day 10 total infusions0.50.51.10.60.70.90.70.7-0.4-0.60.60.61.00.80.90.71.00.70.5-0.40.60.90.70.7
Short access total infusions0.00.00.2-0.1-0.00.10.2-0.1-0.2-0.5-0.20.20.20.20.1-0.40.10.1-0.3-0.2-0.10.2-0.2-0.0
Short access day 1 locomotion0.60.70.90.90.90.90.80.9-0.0-0.30.81.00.90.90.90.70.90.90.9-0.10.90.71.00.9
Short access day 10 total locomotion0.40.42.00.60.20.41.1-0.00.8-1.40.20.80.50.80.40.5-0.20.80.31.00.20.50.20.3
Short access total locomotion0.50.52.00.50.30.51.10.11.2-1.40.30.90.60.80.50.5-0.10.80.41.10.30.20.40.4
Compulsive drug intake0.20.20.80.50.20.30.60.20.7-0.30.40.70.20.70.30.9-0.10.60.30.60.40.00.40.4
One hour access (0.3 mA shock)0.00.10.3-0.2-0.2-0.00.0-0.2-0.3-0.6-0.3-0.10.1-0.1-0.00.20.1-0.1-0.5-0.2-0.3-0.1-0.3-0.2
One hour access (shock baseline)0.10.20.5-0.5-0.3-0.2-0.5-0.3-0.60.2-0.4-0.4-0.2-0.3-0.3-0.4-0.0-0.3-0.7-0.6-0.40.1-0.6-0.3
Number of responses in last shaping day1.51.62.31.41.31.41.31.2-0.1-0.71.21.41.41.31.41.21.31.41.50.21.31.11.51.3
Context. condit. distance diff. score8.19.914.1-3.8-3.3-3.4-3.1-3.2-0.11.5-3.3-3.4-3.5-3.5-3.4-3.6-3.0-3.4-3.5-0.4-3.4-2.9-3.5-3.4
Locomotion velocity, session 10.40.40.70.80.60.50.60.50.7-0.10.80.70.30.80.40.70.20.70.80.70.70.30.70.7
Locomotion distance, session 12.22.94.52.11.71.82.01.51.0-1.31.91.81.62.11.61.91.01.92.01.41.71.21.91.8
Locomotion velocity, session 21.41.72.71.61.31.31.41.20.5-0.61.51.41.21.51.31.50.91.51.50.71.41.01.51.4
Locomotion distance, session 22.84.06.32.52.02.02.31.71.2-1.52.22.11.82.41.92.41.22.22.41.72.11.32.22.0
Locomotion velocity, session 30.40.52.2-0.7-0.2-0.4-1.00.0-1.41.4-0.3-0.7-0.4-0.7-0.3-0.80.3-0.6-0.5-1.5-0.30.2-0.4-0.3
Locomotion distance, session 30.70.71.2-1.1-0.7-0.8-1.1-0.6-0.60.8-0.8-1.0-0.8-1.1-0.8-1.0-0.5-1.1-0.8-0.7-0.8-0.5-0.8-0.8
Stereotopy head waving bouts, day 30.30.40.70.70.80.60.30.8-0.10.50.80.70.50.70.50.60.60.70.6-0.20.80.70.60.8
Stereotopy head waving duration, day 31.41.72.91.31.51.40.61.6-1.20.71.41.21.31.21.31.11.71.21.2-1.11.41.61.31.4
Locomotion velocity, session 710.411.415.5-3.9-3.7-3.6-3.0-3.70.40.7-3.7-3.7-3.6-3.6-3.6-3.7-3.5-3.7-3.80.2-3.8-3.3-3.8-3.7
Locomotion distance, session 77.29.212.9-3.3-3.4-3.3-2.2-3.51.2-0.1-3.4-3.0-3.2-3.0-3.3-3.1-3.6-3.1-3.31.2-3.4-3.3-3.4-3.4
Stereotopy head waving bouts, day 71.51.72.81.31.51.40.71.6-1.00.41.51.21.31.21.41.21.71.21.3-0.91.41.51.41.5
Stereotopy head waving duration, day 71.51.83.61.11.61.40.31.7-1.61.01.51.01.31.01.31.01.91.01.2-1.51.41.71.31.4
Locomotion velocity, session 80.50.61.3-0.9-0.6-0.7-1.1-0.5-0.51.1-0.5-0.9-0.9-0.9-0.8-0.9-0.4-0.9-0.7-0.6-0.7-0.4-0.7-0.6
Locomotion distance, session 80.71.11.8-1.1-1.1-1.1-0.7-1.20.6-0.0-1.0-1.0-1.2-1.0-1.2-1.1-1.4-1.0-1.00.8-1.1-1.1-1.1-1.1
Degree of sensitization distance5.45.49.5-2.2-2.7-2.5-1.1-2.91.8-1.0-2.6-2.0-2.4-2.0-2.4-2.1-3.1-2.1-2.51.8-2.6-2.7-2.6-2.6
Degree of sensitization stereotypy0.80.91.90.81.11.00.31.2-1.10.41.00.81.00.71.00.71.40.80.8-1.01.01.20.91.0
Condit. Reinf. active minus inactive responses1.11.21.81.31.11.21.11.10.0-0.51.11.41.21.21.21.11.11.31.10.11.21.21.21.2
Condit. Reinf. active-inactive response ratio0.10.21.30.10.30.1-0.40.4-0.41.10.40.2-0.00.00.1-0.00.40.20.1-0.70.30.40.20.3
Condit. Reinf. active responses1.92.33.81.91.31.51.91.20.8-1.61.41.91.61.71.51.51.11.81.51.01.41.31.51.4
Condit. Reinf. inactive responses2.52.99.92.01.11.52.60.71.7-3.11.11.91.71.91.51.70.51.91.62.31.20.81.41.2
Incentive salience index mean2.83.44.82.21.92.01.91.8-0.0-1.01.92.12.12.12.01.91.82.11.90.11.91.92.01.9
Condit. Reinf. lever presses3.74.97.22.72.22.42.42.10.3-1.62.22.52.52.52.42.42.02.52.40.62.32.12.42.3
Time in familiar zone, hab. session 10.20.20.4-0.5-0.5-0.5-0.4-0.50.50.1-0.4-0.4-0.5-0.5-0.5-0.4-0.6-0.5-0.50.3-0.5-0.7-0.5-0.5
Time in novel zone, hab. session 10.50.52.8-0.30.20.0-0.80.4-1.71.40.0-0.30.0-0.30.1-0.40.7-0.3-0.2-1.70.10.6-0.00.1
Total zone transitions, hab. session 11.01.41.91.41.31.31.11.20.1-0.61.31.21.31.41.31.31.21.21.40.21.31.11.41.3
Total locomotion distance, hab. session 11.21.72.61.61.21.31.61.00.8-1.31.31.51.31.61.21.50.71.51.41.11.30.91.31.3
Locomotion velocity, hab. session 12.43.45.52.31.61.82.31.41.4-2.11.82.11.82.21.72.20.92.12.01.81.71.21.91.7
Time in familiar zone, hab. session 22.12.14.1-1.7-1.3-1.6-2.0-1.1-0.02.0-1.2-1.7-1.7-1.6-1.6-1.4-1.1-1.7-1.4-0.9-1.3-1.3-1.4-1.3
Time in novel zone, hab. session 21.31.32.21.41.01.21.50.9-0.0-1.31.01.31.31.31.31.10.91.31.10.61.11.11.11.1
Total zone transitions, hab. session 22.43.14.32.12.01.91.42.0-0.2-0.02.11.91.71.91.81.81.92.02.0-0.22.01.82.02.0
Total locomotion distance, hab. session 20.91.31.91.41.21.21.11.10.3-0.31.31.31.01.31.11.20.91.31.30.31.31.01.21.2
Locomotion velocity, hab. session 21.62.13.11.71.61.51.31.50.2-0.31.71.61.41.61.51.61.41.71.60.21.61.41.61.6
Novel to familiar place preference ratio0.60.61.21.00.60.71.10.50.5-1.10.60.90.90.90.80.90.50.80.80.60.70.40.80.7
Novelty place preference0.60.61.21.00.60.71.10.50.7-1.10.60.90.81.00.81.00.40.90.80.80.70.30.80.7
Time in novel zone, NPP test0.70.81.31.10.70.81.10.70.6-0.90.81.10.91.10.91.10.51.00.90.70.90.50.90.8
Total zone transitions, NPP test1.01.42.31.51.01.11.50.81.1-1.31.21.31.01.41.01.30.41.31.41.51.10.61.21.1
Total locomotion distance, NPP test1.31.89.01.30.40.61.9-0.02.6-2.60.61.30.61.20.51.2-0.71.21.03.00.6-0.20.70.6
Locomotion velocity, NPP test1.01.57.41.10.30.51.8-0.12.3-2.50.51.10.51.10.41.0-0.71.00.82.70.4-0.20.60.4
Pavlov. Cond. lever latency1.31.72.6-1.5-1.2-1.4-1.5-1.20.11.2-1.2-1.5-1.6-1.4-1.5-1.4-1.3-1.5-1.3-0.2-1.3-1.2-1.4-1.3
Pavlov. Cond. magazine entry latency0.10.10.70.30.30.40.50.3-0.3-0.80.10.20.60.30.50.30.50.20.3-0.00.20.40.40.2
Pavlov. Cond. change in total contacts3.84.06.02.22.12.21.72.2-0.9-0.72.02.02.42.12.32.02.52.02.0-0.72.12.32.22.1
Pavlov. Cond. index score1.11.42.41.31.21.31.21.2-0.6-0.91.11.21.61.21.41.21.41.21.2-0.31.11.41.31.2
Pavlov. Cond. latency score1.11.52.41.31.21.31.31.2-0.4-1.11.01.31.61.31.41.21.31.21.2-0.11.11.31.31.2
Pavlov. Cond. lever contacts1.31.52.51.41.21.41.41.2-0.5-1.21.11.31.61.31.51.21.31.31.2-0.01.21.31.31.2
Pavlov. Cond. magazine entry number0.70.81.7-0.8-1.0-1.0-0.7-1.00.80.4-0.8-0.8-1.2-0.8-1.1-0.8-1.3-0.7-0.90.6-0.9-1.1-1.0-0.9
Pavlov. Cond. intertrial magazine entries1.21.42.71.51.01.11.60.80.9-1.51.01.51.11.31.11.30.51.51.21.21.10.91.11.1
Pavlov. Cond. lever-magazine prob. diff.1.21.52.51.31.31.41.11.3-0.8-0.81.11.21.61.21.51.21.51.11.2-0.51.21.51.41.2
Pavlov. Cond. response bias0.70.81.70.80.91.00.71.0-1.1-0.40.70.71.20.71.10.71.30.70.8-0.80.81.20.90.8
Bone: apparent density0.30.52.7-0.1-0.5-0.40.5-0.71.6-1.3-0.4-0.2-0.3-0.1-0.40.2-0.9-0.20.01.7-0.4-1.0-0.3-0.4
Bone surface0.30.62.30.80.30.41.10.11.5-1.50.40.60.60.70.51.0-0.00.60.71.40.4-0.10.60.4
Bone volume0.40.62.40.80.20.41.20.01.5-1.50.30.70.50.80.40.9-0.10.70.71.50.4-0.10.50.3
Bone: connectivity density1.01.64.8-0.7-1.3-1.1-0.0-1.52.2-1.2-1.1-0.8-1.2-0.7-1.2-0.4-1.9-0.8-0.72.2-1.1-1.8-1.0-1.2
Bone: cortical apparent density1.82.33.9-2.0-1.5-1.6-1.8-1.3-0.81.2-1.6-1.8-1.4-1.8-1.4-1.7-0.9-1.9-1.6-1.2-1.6-1.2-1.6-1.6
Bone: cortical area0.40.61.20.80.70.90.90.7-0.2-0.80.60.61.10.71.00.81.00.70.8-0.10.70.70.80.7
Bone: cortical porosity2.22.43.11.81.71.71.31.7-0.5-0.31.71.71.61.61.71.61.61.71.7-0.31.71.71.71.7
Bone: cortical porosity2.62.83.71.91.81.91.51.8-0.5-0.61.81.81.91.71.91.71.81.81.8-0.21.81.81.81.8
Bone: cortical thickness0.10.20.60.30.40.50.40.4-0.6-0.40.20.20.70.20.60.30.70.20.3-0.60.30.50.30.3
Bone: cortical thickness0.70.81.2-1.1-0.9-0.9-1.0-0.7-0.60.6-1.0-1.0-0.7-1.1-0.8-1.0-0.5-1.1-1.0-0.8-0.9-0.7-0.9-0.9
Bone: cortical tissue density2.02.54.2-2.1-1.6-1.6-1.9-1.3-0.91.3-1.7-1.9-1.5-1.9-1.5-1.8-0.9-1.9-1.7-1.3-1.6-1.3-1.7-1.6
Bone: elastic displacement1.92.23.31.81.41.51.81.21.0-1.51.51.61.51.61.41.71.01.61.71.21.41.01.61.4
Bone: elastic work4.45.78.42.92.32.52.92.11.0-2.32.42.62.62.72.52.81.92.62.71.32.41.92.62.4
Bone: endosteal estimation0.20.30.60.70.50.60.70.50.4-0.60.50.50.70.70.60.80.50.50.70.40.60.30.60.5
Bone: endosteal perimeter0.71.42.31.51.11.21.50.91.0-1.21.21.21.11.41.11.50.71.31.41.11.20.71.31.2
Bone: final force0.20.30.60.50.50.60.50.6-0.2-0.30.40.30.80.50.70.60.80.40.5-0.30.50.50.60.5
Bone: final moment0.60.91.71.10.91.11.11.0-0.0-0.80.80.91.31.01.21.11.20.91.0-0.10.90.91.10.9
Bone: marrow area0.20.30.60.70.50.60.80.40.5-0.70.50.50.60.70.60.80.40.50.70.50.50.20.60.5
Bone: maximum diameter0.20.30.90.40.70.60.20.7-0.90.20.50.30.70.30.70.50.90.30.5-0.70.50.70.50.6
Bone: maximum force0.71.22.11.11.21.21.01.2-0.3-0.51.00.91.41.11.41.21.41.01.2-0.41.11.11.21.1
Bone: maximum moment1.32.33.71.71.51.71.61.6-0.1-1.01.41.41.91.61.81.71.81.51.7-0.11.51.51.71.5
Bone: minimum diameter1.32.53.81.81.61.81.71.6-0.2-1.21.51.62.01.61.91.71.71.61.70.11.61.51.71.6
Bone: periosteal estimation0.30.50.90.80.70.80.90.60.2-0.80.60.61.00.80.90.90.80.70.80.20.70.50.80.7
Bone: periosteal perimeter0.50.81.31.00.80.91.10.70.7-0.90.90.80.91.10.91.10.60.81.10.70.80.50.90.8
Bone: post-yield work1.41.93.2-1.8-1.4-1.4-1.5-1.2-0.90.8-1.6-1.6-1.1-1.7-1.2-1.6-0.8-1.6-1.6-1.2-1.5-1.0-1.5-1.5
Bone: stiffness0.10.10.7-0.10.20.2-0.30.4-0.80.60.1-0.20.2-0.00.20.10.6-0.20.1-0.90.20.30.20.2
Bone: tissue strength0.40.40.80.70.50.60.90.40.5-0.80.50.60.70.70.70.80.40.60.70.60.60.40.70.5
Bone: trabecular number0.50.83.8-0.2-0.8-0.60.5-1.01.6-1.6-0.6-0.2-0.5-0.1-0.6-0.1-1.3-0.3-0.31.9-0.7-1.1-0.5-0.7
Bone: trabecular spacing0.60.82.40.50.90.8-0.21.1-1.41.30.90.60.60.40.70.31.30.50.5-1.60.81.20.70.9
Bone: trabecular thickness0.20.31.60.50.20.40.80.10.7-1.30.20.40.60.50.50.60.10.40.50.80.30.00.40.2
Bone: trabecular tissue density0.50.71.50.60.80.70.21.0-1.10.70.70.70.80.60.80.41.10.70.6-1.20.81.10.70.8
Breakpoint value in progressive ratio session0.10.10.7-0.1-0.2-0.3-0.3-0.20.80.5-0.0-0.1-0.5-0.0-0.4-0.0-0.5-0.2-0.00.5-0.1-0.7-0.2-0.1
Distance traveled before self-admin1.21.32.11.31.31.20.71.3-0.40.41.31.21.11.31.21.01.41.31.0-0.71.31.51.21.3
Distance traveled after self-admin0.40.41.30.30.70.5-0.10.8-0.81.10.70.30.40.30.40.10.90.30.5-1.10.60.80.40.6
Delta time in closed arm before/after self-admin0.10.10.4-0.0-0.2-0.10.3-0.30.4-0.7-0.2-0.0-0.10.0-0.1-0.1-0.40.0-0.20.6-0.20.0-0.2-0.2
Delta time in open arm before/after self-admin0.70.71.2-0.9-0.9-0.9-0.8-0.90.60.2-0.8-0.9-0.9-0.9-0.9-0.7-0.9-0.9-0.90.3-0.8-1.1-0.8-0.8
Diff in mean of infusions in LGA sessions0.80.91.71.11.11.00.51.2-0.50.41.10.90.90.90.90.91.10.91.3-0.41.10.91.11.1
Extinction: sum of active levers before priming0.80.82.1-0.5-0.9-0.8-0.0-1.11.0-1.2-0.9-0.8-0.7-0.8-0.8-0.5-1.2-0.6-0.61.5-0.9-1.1-0.8-0.9
Active lever presses in extinction session 60.90.81.2-1.0-1.0-1.0-0.7-1.0-0.2-0.0-1.1-1.0-0.9-1.1-0.9-1.0-1.0-1.0-1.00.1-1.0-1.0-1.1-1.1
Delta distance traveled before/after self-admin0.50.62.6-0.9-0.3-0.5-1.1-0.1-1.01.6-0.3-0.8-0.6-0.9-0.5-0.9-0.0-0.9-0.3-1.2-0.4-0.3-0.6-0.4
Delta ambulatory time before/after self-admin0.30.31.9-0.6-0.1-0.2-0.80.1-1.01.4-0.1-0.5-0.3-0.6-0.2-0.60.2-0.6-0.0-1.1-0.1-0.0-0.3-0.2
Time in closed arm before self-admin0.10.21.4-0.10.30.1-0.40.5-0.41.20.30.10.0-0.00.10.10.5-0.00.4-0.80.30.20.20.3
Time in closed arm after self-admin0.20.20.40.40.50.40.40.50.40.30.60.60.30.60.40.50.40.50.60.00.50.50.50.5
Time in open arm before self-admin0.20.20.60.80.40.50.70.4-0.0-0.30.50.60.40.70.50.40.30.60.70.30.50.50.40.5
Time in open arm after self-admin0.50.60.9-0.7-0.8-0.8-0.6-0.90.4-0.1-0.8-0.8-0.8-0.8-0.9-0.7-0.9-0.7-0.90.4-0.8-0.9-0.9-0.8
Sum of active levers in priming session hrs 5-62.52.43.2-1.6-1.7-1.8-1.5-1.7-0.10.6-1.6-1.8-1.8-1.8-1.7-1.8-1.7-1.6-1.60.1-1.6-1.6-1.8-1.7
Time to tail flick, vehicle, before self-admin0.30.31.40.80.30.50.90.3-0.4-1.20.30.60.70.50.60.50.30.60.50.50.40.30.50.4
Time to tail flick, vehicle, after self-admin0.70.86.5-0.5-0.0-0.5-1.50.2-1.22.60.0-0.7-0.7-0.8-0.5-0.50.2-0.7-0.3-1.5-0.1-0.1-0.2-0.1
Time to tail flick, test, before self-admin0.40.42.30.40.20.50.90.01.0-1.50.20.50.50.40.40.5-0.10.60.41.10.20.20.30.3
Time to tail flick, test, after self-admin6.26.411.9-2.5-2.8-2.7-1.5-3.01.6-0.3-2.6-2.3-2.8-2.4-2.8-2.5-3.4-2.3-2.61.8-2.7-2.9-2.8-2.7
Delta time to tail flick, vehicle, before/after SA1.51.54.0-1.5-0.9-1.2-1.8-0.7-0.42.0-0.9-1.4-1.3-1.4-1.2-1.3-0.6-1.5-1.1-1.2-1.0-0.8-1.1-1.0
Delta time to tail flick, test, before/after SA6.86.18.1-2.6-2.6-2.8-2.4-2.50.01.3-2.5-2.7-2.8-2.6-2.8-2.6-2.6-2.8-2.60.1-2.6-2.6-2.7-2.6
Ambulatory time before self-admin0.90.91.41.11.01.10.91.1-0.4-0.11.01.11.11.11.10.91.11.20.8-0.51.01.20.91.1
Ambulatory time after self-admin0.80.91.70.71.10.90.11.2-1.11.21.00.70.80.60.80.41.30.70.8-1.31.01.30.71.0
Total heroin consumption1.11.33.11.11.21.10.41.4-1.70.61.10.71.30.91.31.01.80.81.1-1.41.21.11.31.1
Area under the delay curve0.30.30.50.40.50.60.60.50.0-0.30.40.60.70.50.70.50.60.50.6-0.30.50.70.50.5
Delay disc. indifference point, 0s delay1.31.42.71.40.91.01.60.61.5-1.51.01.41.01.30.91.30.31.41.41.61.00.51.11.0
Delay disc. indifference point, 16s delay0.10.10.2-0.5-0.3-0.2-0.2-0.2-0.30.1-0.4-0.3-0.1-0.4-0.1-0.3-0.1-0.4-0.2-0.4-0.30.0-0.4-0.3
Delay disc. indifference point, 2s delay2.42.74.41.91.61.71.71.60.8-0.61.82.01.61.91.61.91.32.02.10.51.81.51.81.7
Delay disc. indifference point, 24s delay0.10.10.7-0.2-0.0-0.0-0.30.1-0.50.8-0.1-0.1-0.0-0.20.0-0.20.3-0.1-0.1-0.8-0.00.2-0.2-0.0
Delay disc. indifference point, 4s delay0.40.41.20.40.60.60.20.8-0.80.60.50.50.70.40.70.41.00.50.7-1.10.61.00.50.6
Delay disc. indifference point, 8s delay0.10.10.3-0.10.10.30.20.2-0.2-0.3-0.10.10.50.10.40.10.50.10.1-0.60.10.50.20.1
Delay discount exponential model param0.30.30.8-0.3-0.6-0.6-0.5-0.60.30.1-0.4-0.6-0.8-0.5-0.7-0.5-0.9-0.5-0.60.7-0.5-0.9-0.5-0.5
Delay discount hyperbolic model param0.70.81.5-0.7-0.9-1.0-0.7-1.00.40.0-0.8-0.9-1.1-0.8-1.0-0.8-1.2-0.9-1.00.7-0.9-1.2-0.8-0.9
Fecal boli incidents, locomotor time 10.60.62.10.30.60.80.30.8-1.4-0.10.40.31.20.31.00.41.40.30.6-1.50.60.90.60.5
Change in fecal boli incidents, locomotor task0.70.71.3-1.0-0.8-1.0-1.0-0.70.71.0-0.6-0.8-1.1-0.8-1.0-0.7-0.9-0.8-1.0-0.1-0.6-0.8-0.7-0.7
Time >=10cm from walls, locomotor time 10.40.42.50.70.20.41.00.00.8-1.60.20.50.50.50.40.6-0.10.50.41.30.2-0.00.40.2
Bouts of movement, locomotor time 10.40.43.4-0.10.3-0.0-1.00.4-1.41.90.3-0.3-0.4-0.3-0.3-0.30.4-0.3-0.1-1.20.20.0-0.00.2
Total resting periods, locomotor time 11.01.16.0-0.9-0.3-0.7-1.7-0.1-1.52.4-0.3-1.0-1.1-1.0-0.9-1.0-0.1-1.0-0.8-1.6-0.5-0.4-0.7-0.5
Rest time, locomotor task time 11.41.57.4-1.3-0.6-0.9-1.9-0.3-1.32.7-0.6-1.4-1.2-1.4-1.0-1.1-0.2-1.4-0.8-1.7-0.7-0.5-0.8-0.7
Distance moved, locomotor task time 10.50.52.70.80.10.41.2-0.11.2-1.60.20.80.50.80.40.6-0.30.80.21.40.3-0.10.30.2
Vertical activity count, locomotor time 14.14.26.22.52.02.12.41.80.6-1.62.02.42.22.42.22.31.62.42.10.92.11.92.32.1
Time >=10cm from walls, locomotor time 20.10.10.30.20.40.40.10.5-0.00.30.40.30.40.30.40.40.50.30.3-0.40.40.40.50.4
Bouts of movement, locomotor time 21.01.05.2-0.9-0.5-0.8-1.7-0.2-1.42.3-0.5-1.1-1.0-1.1-0.8-0.9-0.0-1.1-0.6-1.6-0.5-0.2-0.6-0.6
Total resting periods, locomotor time 21.81.97.2-1.4-0.7-1.1-2.2-0.4-1.92.7-0.8-1.5-1.2-1.5-1.1-1.4-0.1-1.5-0.9-2.1-0.8-0.3-1.0-0.9
Rest time, locomotor task time 22.93.49.7-2.1-1.1-1.3-2.6-0.6-3.12.5-1.4-2.2-1.2-2.2-1.2-2.00.1-2.2-1.5-3.0-1.4-0.1-1.5-1.3
Distance moved, locomotor task time 22.02.45.31.81.01.22.30.72.1-2.31.11.71.41.71.31.80.31.71.42.21.20.51.41.2
Vertical activity count, locomotor time 24.85.37.42.72.22.32.72.01.4-1.72.32.72.32.72.32.71.72.72.61.32.31.82.62.3
Weight adjusted by age2.42.74.21.81.91.81.21.9-0.7-0.11.81.51.81.61.82.01.91.62.1-0.41.81.72.01.8
Seeking ratio, delayed vs. immediate footshock1.31.53.21.30.91.11.80.71.5-1.71.01.51.11.41.11.50.41.41.11.61.00.51.21.1
Locomotion in novel chamber0.10.10.40.2-0.00.10.3-0.0-0.5-0.6-0.10.30.30.20.20.20.10.1-0.1-0.1-0.00.4-0.0-0.0
Locomotion in novel chamber post-restriction0.10.20.7-0.20.40.3-0.30.5-0.80.70.3-0.10.2-0.00.2-0.00.50.00.1-0.80.20.50.20.3
Progressive ratio0.50.61.10.70.90.90.40.9-0.70.10.80.70.90.60.90.71.10.60.7-0.60.81.00.80.8
Food seeking constrained by brief footshock3.74.68.7-2.3-1.8-2.2-3.0-1.5-1.62.9-1.7-2.4-2.5-2.4-2.3-2.4-1.4-2.4-2.1-1.5-1.9-1.4-2.1-1.9
Seeking ratio, punishment vs. effort1.61.92.8-1.5-1.3-1.5-1.7-1.2-0.61.4-1.3-1.6-1.7-1.5-1.6-1.6-1.2-1.4-1.4-0.5-1.4-1.1-1.5-1.4
Run reversals in cocaine runway, females0.50.51.8-0.4-0.7-0.50.2-0.90.9-1.4-0.7-0.3-0.5-0.3-0.6-0.4-1.1-0.3-0.81.2-0.7-0.6-0.8-0.7
Run reversals in cocaine runway, males2.22.25.80.61.71.50.01.9-2.11.11.30.91.60.71.50.92.40.90.9-2.41.31.91.41.4
Latency to leave start box in cocaine runway0.30.31.8-0.20.60.4-0.40.7-0.31.30.50.00.20.10.30.00.90.10.4-1.20.40.70.50.5
Latency to leave start box in cocaine runway, F0.91.03.10.31.10.8-0.31.3-1.11.61.00.30.70.40.80.41.60.40.9-1.80.91.11.00.9
Latency to leave start box in cocaine runway, M0.30.21.9-0.3-0.3-0.20.2-0.41.4-0.7-0.2-0.3-0.3-0.0-0.30.0-0.60.0-0.21.1-0.3-0.3-0.2-0.2
Cd content in liver0.10.10.60.30.10.20.6-0.00.3-0.80.00.50.30.20.30.2-0.00.50.10.40.20.20.10.1
Co content in liver0.70.85.3-0.9-0.1-0.4-1.50.1-1.12.3-0.2-0.8-0.6-0.7-0.5-0.70.3-0.8-0.5-1.8-0.2-0.1-0.4-0.2
Cu content in liver0.20.21.5-0.60.1-0.1-0.80.2-0.51.20.0-0.3-0.2-0.3-0.1-0.30.4-0.3-0.2-1.2-0.00.3-0.10.0
Fe content in liver0.50.61.1-0.6-0.9-0.7-0.1-1.00.5-0.9-0.8-0.7-0.6-0.6-0.7-0.6-1.0-0.7-0.70.9-0.9-0.9-0.8-0.8
K content in liver0.60.61.2-0.7-0.9-0.8-0.5-1.00.8-0.2-0.8-0.7-0.9-0.7-0.9-0.7-1.1-0.7-0.80.7-0.8-0.8-0.9-0.8
Mg content in liver0.50.50.9-0.7-0.7-0.6-0.3-0.80.7-0.4-0.6-0.6-0.7-0.6-0.8-0.6-0.9-0.6-0.60.8-0.7-0.7-0.7-0.7
Mn content in liver0.70.83.9-0.3-0.7-0.50.4-1.01.9-1.5-0.5-0.1-0.6-0.2-0.6-0.2-1.3-0.1-0.42.0-0.6-0.9-0.5-0.6
Na content in liver7.98.410.83.13.23.32.73.1-0.3-1.43.12.93.33.13.33.13.02.93.2-0.03.13.23.23.1
Rb content in liver1.01.21.7-1.3-1.2-1.2-1.0-1.2-0.10.3-1.2-1.0-1.1-1.3-1.2-1.3-1.1-1.0-1.3-0.1-1.2-1.0-1.3-1.2
Se content in liver3.13.76.32.11.61.82.51.22.5-2.31.82.41.72.11.72.10.72.42.02.21.81.21.81.8
Sr content in liver0.20.21.7-0.1-0.2-0.20.2-0.41.3-0.5-0.00.0-0.30.0-0.30.0-0.70.0-0.01.1-0.1-0.5-0.1-0.1
Zn content in liver3.13.44.31.82.02.01.72.00.2-0.62.02.12.01.92.01.91.92.12.0-0.22.02.02.12.0