Hub : Genes

Tab1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017285 0.03 0.02 4.8e-03 0.03 0.01 0.01 0.02 5.9e-04 5.2e-02 7.8e-03 6.0e-03
2 BLA gene expression ENSRNOG00000017285 0.22 0.1 2.1e-07 0.12 0.11 0.1 0.13 3.9e-07 2.5e-06 6.6e-06 1.8e-07
3 Brain gene expression ENSRNOG00000017285 0.22 0.09 0.0e+00 0.19 0.18 0.21 0.09 1.7e-17 1.2e-16 2.8e-19 7.2e-09
4 LHb gene expression ENSRNOG00000017285 0.16 0.09 6.0e-03 0.14 0.04 0 0 4.3e-04 4.0e-02 3.0e-01 2.8e-01
5 Liver gene expression ENSRNOG00000017285 0.1 0.05 6.3e-09 0.06 0.07 0.06 0.06 4.3e-07 6.8e-08 3.9e-07 5.6e-07
6 NAcc gene expression ENSRNOG00000017285 0.15 0.07 8.5e-10 0.12 0.13 0.13 0.12 3.4e-09 8.9e-10 1.2e-09 2.2e-09
7 OFC gene expression ENSRNOG00000017285 0.42 0.16 3.8e-05 0.07 0.1 0.14 0.09 8.1e-03 3.0e-03 2.8e-04 3.1e-03
8 PL gene expression ENSRNOG00000017285 0.2 0.08 5.6e-12 0.17 0.16 0.16 0.16 1.0e-12 5.1e-12 2.0e-12 1.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.20.72.1-0.0-1.0-0.4-0.30.6-1.3-0.3-1.5
BMI without tail0.10.20.7-0.50.30.40.3-0.8-0.60.0-0.5
Body weight0.93.98.60.5-2.2-2.0-2.91.8-1.6-1.2-2.4
Epididymis fat weight3.07.012.0-0.3-3.5-3.2-2.91.0-2.9-2.4-3.2
Glucose0.10.10.40.60.40.4-0.6-0.00.4-0.3-0.2
Heart weight0.50.84.40.5-0.1-0.1-2.10.9-0.3-0.4-0.8
Left kidney weight5.014.526.61.7-5.2-4.4-3.93.8-3.2-2.1-4.8
Right kidney weight4.513.021.82.8-4.3-3.6-4.34.7-2.3-1.5-4.0
Tail length0.10.31.8-0.10.1-0.3-1.4-0.4-0.1-0.7-0.2
Length with tail0.93.311.70.5-1.7-2.1-3.41.3-0.8-1.4-1.6
Length without tail1.53.28.10.8-2.0-2.2-2.82.2-0.7-1.0-1.4
Liver weight, left1.42.33.2-0.5-1.8-1.8-1.8-0.1-1.7-1.7-1.6
Liver weight, right5.38.813.0-1.6-3.3-3.6-3.0-0.7-3.4-3.4-3.3
Parametrial fat weight0.20.31.1-0.6-0.5-0.4-1.0-0.0-0.6-0.6-0.3
Retroperitoneal fat weight3.310.918.60.2-4.3-3.7-4.01.8-3.4-2.8-4.1
Intraocular pressure0.50.72.10.5-1.5-0.9-0.40.8-0.6-0.5-1.0
Extensor digitorum longus weight0.31.01.9-0.81.11.41.3-1.40.20.60.5
Soleus weight0.61.72.81.21.21.31.10.71.71.31.6
Tibialis anterior weight1.24.18.90.12.22.63.0-0.71.72.12.1
Tibia length0.41.03.91.1-1.0-1.1-0.32.0-0.00.6-0.6
Number of licking bursts0.50.61.8-0.60.90.60.8-0.50.70.61.3
Food consumed during 24 hour testing period0.60.73.11.3-0.20.0-0.11.80.10.7-0.3
Times rat made contact with spout0.20.30.7-0.30.40.20.10.60.30.80.9
Mean time between licks in bursts0.40.61.3-0.50.91.10.9-1.00.40.30.6
Mean num. licks in bursts0.60.71.20.1-1.1-1.0-1.00.8-0.9-0.5-1.0
Std. dev. time between licks in bursts1.01.22.30.61.41.50.50.11.51.11.2
Water consumed over 24 hours0.30.30.80.10.40.3-0.10.90.30.80.8
Indifference point 0 sec0.40.61.40.51.21.2-0.1-0.11.00.50.7
Indifference point AUC1.82.14.00.81.01.01.90.91.61.72.0
Indifference point function ln k2.94.07.5-0.6-2.1-2.0-2.4-0.4-2.2-2.3-2.7
Indifference point function log k2.94.07.5-0.6-2.1-2.0-2.4-0.4-2.2-2.3-2.7
Delay discounting total patch changes 0 sec0.50.81.90.41.41.40.2-0.31.00.70.9
Delay discounting total patch changes 12 sec0.81.12.21.50.71.11.00.91.21.00.8
Delay discounting total patch changes 18 sec2.83.75.31.91.82.11.51.52.32.31.9
Delay discounting total patch changes 24 sec0.91.22.40.51.01.51.20.21.31.11.1
Delay discounting total patch changes 6 sec2.63.95.71.32.32.31.41.02.42.22.4
Delay discounting time to switch 0 sec0.20.20.90.7-0.20.40.60.3-0.10.1-0.9
Delay discounting water rate 0 sec0.20.40.90.10.90.3-0.80.00.70.31.0
Delay discounting water rate 12 sec0.30.51.3-0.70.40.1-1.0-1.2-0.2-0.90.1
Delay discounting water rate 18 sec0.60.81.70.11.30.7-0.8-0.21.20.31.3
Delay discounting water rate 24 sec0.70.94.7-0.0-0.4-0.8-2.2-0.0-0.5-1.1-0.7
Delay discounting water rate 6 sec0.60.92.9-1.2-0.0-0.5-1.1-1.7-0.3-1.10.1
Locomotor activity0.71.13.00.4-1.1-0.9-1.71.0-0.8-0.7-1.3
Locomotor testing distance0.10.20.7-0.8-0.3-0.2-0.5-0.5-0.4-0.3-0.2
Locomotor testing rearing0.50.81.50.2-1.2-0.8-0.90.6-1.1-0.7-1.2
Light reinforcement 10.10.10.30.20.20.60.00.10.40.40.1
Light reinforcement 21.72.24.4-0.8-1.8-1.4-0.9-0.7-1.9-1.5-2.1
Reaction time number correct1.01.54.4-2.1-0.7-1.00.1-1.8-1.0-1.3-0.3
Reaction time mean minus median0.00.00.10.30.10.1-0.2-0.1-0.0-0.1-0.1
Reaction time mean minus median AUC0.40.51.00.2-0.7-0.5-0.8-0.1-0.8-0.9-1.0
Reaction time num false alarms0.10.10.4-0.30.20.1-0.7-0.5-0.2-0.5-0.1
Reaction time num false alarms AUC0.10.10.4-0.40.10.0-0.5-0.6-0.2-0.50.0
Reaction time trials correct on left1.01.54.4-2.1-0.7-1.00.1-1.8-1.0-1.3-0.3
Reaction time trials on left1.01.54.5-2.1-0.7-1.00.1-1.9-0.9-1.3-0.2
Reaction time mean0.10.10.30.60.2-0.0-0.4-0.2-0.0-0.3-0.2
Reaction time mean AUC0.10.10.20.40.1-0.2-0.4-0.2-0.1-0.3-0.2
Median of all reaction times0.10.10.40.60.40.1-0.1-0.30.1-0.2-0.0
Reaction time omissions0.30.42.00.10.40.61.4-0.60.20.20.5
Reaction time false alarm rate0.10.10.30.30.40.4-0.50.10.0-0.00.0
Reaction time premature initiation rate0.91.23.21.80.81.00.11.31.41.10.4
Reaction time premature initiations0.10.20.60.70.30.3-0.00.50.70.30.1
Std. dev. reaction times0.20.30.80.6-0.2-0.4-0.90.2-0.3-0.5-0.5
Reaction time trials completed1.01.54.5-2.1-0.7-1.00.1-1.9-0.9-1.3-0.2
Reaction time trials AUC0.91.33.7-1.9-0.8-1.0-0.0-1.6-1.0-1.2-0.4
Social response proportion0.30.30.80.90.60.90.10.10.30.4-0.3
Social responses0.70.91.90.90.91.40.90.41.11.00.9
Social time2.73.56.31.22.22.52.2-0.32.01.72.0
Conditioned locomotion0.30.30.50.0-0.7-0.5-0.70.1-0.6-0.7-0.7
Cocaine response after cond. corrected0.30.31.01.00.00.30.40.80.50.40.1
Cocaine response after cond. not corrected0.10.10.40.70.00.10.20.30.20.2-0.2
Cocaine response before conditioning0.30.41.2-1.0-0.0-0.3-0.1-1.1-0.5-0.5-0.3
Saline control response0.91.23.0-0.9-0.4-0.8-1.5-1.4-0.9-1.7-0.7
Condit. Reinf. active minus inactive responses1.21.52.51.40.70.71.21.41.51.61.2
Condit. Reinf. active-inactive response ratio1.11.12.61.40.40.50.61.61.21.30.6
Condit. Reinf. active responses0.60.92.51.4-0.10.00.81.60.81.10.4
Condit. Reinf. inactive responses0.20.30.60.4-0.8-0.60.60.8-0.20.3-0.2
Condit. Reinf. lever presses0.40.51.10.30.70.71.0-0.00.90.90.8
Condit. Reinf. lever reinforcers received0.70.92.31.5-0.00.20.81.51.01.00.4
Pavlov. Cond. lever latency0.40.51.3-0.5-1.2-1.10.00.4-1.0-0.3-0.5
Pavlov. Cond. magazine entry latency2.73.15.31.12.32.01.50.22.21.92.0
Pavlov. Cond. change in total contacts2.12.96.22.51.51.60.21.72.31.71.0
Pavlov. Cond. index score1.31.73.11.01.71.60.80.01.81.21.4
Pavlov. Cond. latency score1.72.14.01.11.91.71.00.12.01.41.6
Pavlov. Cond. lever contacts0.20.30.90.20.90.9-0.0-0.50.80.20.3
Pavlov. Cond. magazine entry number0.91.22.2-0.8-1.4-1.1-0.7-0.2-1.5-1.1-1.2
Pavlov. Cond. intertrial magazine entries0.30.41.60.7-0.6-0.30.21.3-0.30.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.11.42.70.81.61.50.7-0.11.61.11.2
Pavlov. Cond. response bias0.81.12.01.01.41.40.70.11.41.00.9
Conditioned reinforcement - actives0.90.92.70.50.50.31.60.60.91.11.3
Conditioned reinforcement - inactives2.52.84.20.71.91.71.70.71.92.02.1
Conditioned locomotion1.31.63.81.70.50.80.82.01.11.60.9
Intermittent access intake day 1-15 change0.30.30.7-0.40.70.10.4-0.80.40.10.8
Intermittent access intake escalation0.30.30.6-0.40.70.10.5-0.80.30.10.7
Intermittent access intake escalation 20.20.20.6-0.20.80.30.2-0.50.40.20.7
Intermitt. access day 1 inactive lever presses0.80.82.11.40.80.70.31.11.01.00.4
Intermitt. access day 15 inactive lever presses0.80.91.70.90.70.50.51.31.11.20.9
Intermitt. access escalation Index0.20.20.4-0.30.40.70.5-0.40.20.30.4
Intermittent access day 1 total infusions1.01.23.01.20.40.51.21.70.81.50.6
Intermittent access day 15 total infusions1.21.42.30.91.10.71.30.91.31.51.3
Intermittent access terminal intake (last 3 days)0.70.71.30.40.80.41.10.60.81.11.1
Intermittent access total infusions1.61.83.51.20.90.81.81.61.11.91.0
Intermittent access day 1 locomotion1.11.12.01.30.70.90.81.40.91.40.7
Intermittent access day 15 total locomotion0.30.31.40.40.20.00.21.20.30.80.3
Intermittent access total locomotion1.01.23.81.30.60.50.32.00.91.30.6
Intermittent access standard deviation0.80.83.01.70.50.30.81.10.70.90.2
Cocaine induced anxiety0.70.92.2-0.4-1.1-0.8-0.90.5-1.1-0.6-1.5
Post-drug Anxiety0.80.83.80.0-0.6-0.8-1.90.7-0.5-0.6-0.9
Baseline Anxiety0.40.41.4-0.10.90.4-0.4-0.40.80.21.2
Lifetime Intake1.92.14.11.50.70.81.82.01.12.00.8
Incentive Sensitization - Responses0.10.10.2-0.4-0.1-0.20.4-0.4-0.0-0.30.2
Incentive Sensitization - Breakpoint0.10.10.2-0.3-0.3-0.40.4-0.3-0.1-0.30.1
Progressive ratio test 1 active lever presses1.92.03.81.20.81.11.71.61.32.01.1
Progressive ratio test 1 breakpoint1.21.22.50.80.70.81.41.21.01.61.0
Progressive ratio test 1 inactive lever presses1.82.04.11.31.21.62.00.81.31.70.9
Progressive ratio test 2 active lever presses1.01.12.60.60.50.51.61.01.01.31.1
Progressive ratio test 2 breakpoint1.21.32.71.00.60.61.61.31.11.41.1
Progressive ratio test 2 inactive lever presses2.02.35.80.51.41.22.40.51.51.81.6
Total sessions with >9 infusions1.01.04.51.4-0.20.20.52.10.41.20.1
Short access day 1 total inactive lever presses3.43.86.12.01.61.81.02.32.22.51.7
Short access day 10 total inactive lever presses0.30.41.60.70.2-0.3-1.30.70.4-0.10.1
Short access day 1 total infusions0.60.61.71.00.30.50.81.30.61.00.3
Short access day 10 total infusions1.31.54.81.8-0.00.41.12.20.51.4-0.1
Short access total infusions1.61.86.01.90.20.61.12.50.71.60.1
Short access day 1 locomotion1.01.01.51.20.91.21.10.81.01.20.7
Short access day 10 total locomotion1.21.32.11.41.41.41.00.31.11.10.8
Short access total locomotion1.71.74.72.20.81.20.71.81.01.50.5
Compulsive drug intake0.90.92.9-0.91.00.60.4-0.90.90.31.7
One hour access (0.3 mA shock)1.72.07.40.11.21.02.70.01.11.61.5
One hour access (shock baseline)0.30.31.70.30.10.21.30.4-0.10.7-0.2
Number of responses in last shaping day3.63.79.41.51.62.13.11.01.72.31.3
Context. condit. distance diff. score6.27.610.6-1.3-3.2-3.1-3.2-0.1-3.3-2.9-3.2
Locomotion velocity, session 10.91.02.21.10.30.50.41.51.31.21.0
Locomotion distance, session 12.73.47.20.31.71.72.70.12.02.12.5
Locomotion velocity, session 20.10.10.40.4-0.30.10.40.6-0.00.4-0.3
Locomotion distance, session 24.56.510.01.42.52.73.20.72.93.02.9
Locomotion velocity, session 33.03.56.6-1.6-2.1-2.6-1.9-0.9-2.0-2.0-1.6
Locomotion distance, session 31.11.24.5-2.1-0.5-1.10.1-1.6-0.7-0.80.4
Stereotopy head waving bouts, day 30.50.62.31.3-0.20.2-0.61.50.30.5-0.3
Stereotopy head waving duration, day 31.21.43.71.3-1.0-0.6-1.61.9-0.4-0.1-1.4
Locomotion velocity, session 70.80.92.1-0.2-1.5-1.0-0.60.2-0.9-1.0-1.2
Locomotion distance, session 70.30.41.00.90.00.40.41.00.70.70.4
Stereotopy head waving bouts, day 73.13.55.6-0.6-2.2-2.0-2.40.1-2.0-1.9-2.4
Stereotopy head waving duration, day 73.74.57.1-1.4-2.3-2.0-2.3-0.8-2.5-2.3-2.7
Locomotion velocity, session 80.70.92.30.8-1.1-0.8-1.11.5-0.4-0.2-0.9
Locomotion distance, session 80.71.01.7-0.6-1.2-1.1-0.9-0.4-1.3-1.1-1.2
Degree of sensitization distance1.61.66.42.5-0.00.8-0.52.10.50.6-0.7
Degree of sensitization stereotypy3.23.54.9-1.3-2.1-2.0-2.0-0.6-2.2-2.0-2.1
Condit. Reinf. active minus inactive responses0.10.10.3-0.10.3-0.1-0.10.10.40.40.6
Condit. Reinf. active-inactive response ratio0.40.51.2-0.6-0.7-1.1-0.8-0.2-0.7-0.6-0.5
Condit. Reinf. active responses0.40.51.1-0.81.10.4-0.1-0.90.70.31.0
Condit. Reinf. inactive responses1.01.22.5-1.11.61.00.0-1.50.80.11.2
Incentive salience index mean0.20.20.6-0.20.60.20.1-0.10.60.50.7
Condit. Reinf. lever presses0.20.30.5-0.10.70.60.2-0.30.60.50.6
Time in familiar zone, hab. session 10.50.41.00.50.20.20.60.90.61.00.7
Time in novel zone, hab. session 10.70.61.8-0.2-0.3-0.4-1.3-0.4-0.8-1.2-0.9
Total zone transitions, hab. session 11.01.43.9-1.90.70.10.7-2.00.4-0.01.4
Total locomotion distance, hab. session 10.70.93.2-1.8-0.1-0.6-0.3-1.7-0.1-0.80.6
Locomotion velocity, hab. session 10.50.72.2-1.50.2-0.20.1-1.50.3-0.20.9
Time in familiar zone, hab. session 21.01.02.2-1.5-0.7-0.8-0.5-1.3-1.1-1.1-0.5
Time in novel zone, hab. session 21.01.02.31.50.70.90.41.31.11.00.6
Total zone transitions, hab. session 22.02.64.70.61.61.51.60.62.02.02.2
Total locomotion distance, hab. session 21.72.23.41.01.61.71.40.41.91.61.8
Locomotion velocity, hab. session 22.12.94.61.01.91.91.60.32.21.82.1
Novel to familiar place preference ratio1.41.54.6-0.8-0.9-1.4-2.10.2-1.2-1.2-0.9
Novelty place preference2.32.36.1-1.0-1.3-1.8-2.50.1-1.6-1.5-1.2
Time in novel zone, NPP test2.62.87.1-1.1-1.4-2.1-2.70.2-1.8-1.6-1.3
Total zone transitions, NPP test1.31.95.0-0.91.41.01.5-1.21.30.92.2
Total locomotion distance, NPP test0.71.02.50.11.01.01.1-0.31.30.91.6
Locomotion velocity, NPP test0.91.22.6-0.11.11.21.4-0.71.20.81.6
Pavlov. Cond. lever latency0.10.10.40.2-0.4-0.3-0.40.6-0.3-0.1-0.2
Pavlov. Cond. magazine entry latency1.11.43.50.61.11.21.90.11.11.41.2
Pavlov. Cond. change in total contacts2.62.84.31.01.81.72.10.41.82.01.8
Pavlov. Cond. index score0.50.61.30.80.60.81.10.40.90.90.7
Pavlov. Cond. latency score0.30.30.60.60.50.60.70.20.60.60.5
Pavlov. Cond. lever contacts0.40.50.80.40.80.90.9-0.30.80.60.7
Pavlov. Cond. magazine entry number0.60.72.4-0.4-0.7-0.7-1.6-0.1-0.7-0.9-0.9
Pavlov. Cond. intertrial magazine entries1.01.22.90.01.61.0-0.10.11.51.11.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.40.50.60.71.20.20.70.80.7
Pavlov. Cond. response bias0.81.02.70.80.81.01.60.21.01.10.9
Bone: apparent density0.10.10.2-0.40.50.30.1-0.20.30.40.2
Bone surface0.10.20.50.00.20.00.30.50.60.70.4
Bone volume0.00.10.2-0.5-0.1-0.30.10.0-0.00.3-0.1
Bone: connectivity density0.00.10.2-0.00.30.1-0.30.30.40.30.2
Bone: cortical apparent density0.71.03.5-1.9-0.3-1.0-0.6-1.3-0.7-0.80.2
Bone: cortical area0.40.62.51.0-0.5-0.30.01.6-0.10.7-0.6
Bone: cortical porosity0.50.62.11.4-0.50.3-0.20.8-0.2-0.3-1.2
Bone: cortical porosity1.01.03.82.0-0.70.2-0.31.5-0.1-0.1-1.3
Bone: cortical thickness0.20.41.10.30.20.41.10.80.21.00.3
Bone: cortical thickness1.11.32.80.60.70.91.71.10.81.71.1
Bone: cortical tissue density0.71.03.3-1.8-0.4-1.0-0.7-1.2-0.7-0.80.1
Bone: elastic displacement0.10.10.40.0-0.5-0.2-0.70.1-0.1-0.5-0.3
Bone: elastic work0.70.93.21.5-0.7-0.1-0.51.80.00.4-1.0
Bone: endosteal estimation0.51.03.11.5-0.6-0.7-0.91.80.10.2-0.9
Bone: endosteal perimeter0.81.73.51.1-1.5-1.3-1.21.4-0.9-0.6-1.9
Bone: final force0.91.45.81.7-0.3-0.00.52.40.41.4-0.3
Bone: final moment1.01.66.61.8-0.20.00.42.60.61.5-0.3
Bone: marrow area0.51.13.41.6-0.6-0.7-0.91.80.10.3-0.9
Bone: maximum diameter1.22.16.71.8-1.3-1.1-1.22.6-0.50.3-1.5
Bone: maximum force1.32.39.62.2-0.20.10.43.10.61.8-0.3
Bone: maximum moment1.42.510.52.2-0.20.10.33.20.71.9-0.3
Bone: minimum diameter0.30.62.51.3-0.4-0.3-0.11.60.20.6-0.6
Bone: periosteal estimation0.61.24.51.5-0.7-0.7-0.62.1-0.10.6-1.0
Bone: periosteal perimeter1.32.14.51.5-1.6-1.2-1.32.1-0.8-0.2-1.9
Bone: post-yield work1.92.65.41.71.21.21.22.01.62.31.4
Bone: stiffness1.01.55.91.90.10.20.02.40.61.4-0.2
Bone: tissue strength0.20.20.40.2-0.5-0.6-0.50.4-0.2-0.2-0.4
Bone: trabecular number0.50.81.1-1.0-0.9-1.0-0.8-0.7-1.0-0.9-0.8
Bone: trabecular spacing1.41.85.42.00.30.70.62.31.11.50.6
Bone: trabecular thickness0.70.91.9-1.4-0.4-0.7-0.4-1.3-1.0-0.9-0.9
Bone: trabecular tissue density0.60.82.4-0.61.61.0-0.3-0.90.80.41.0
Breakpoint value in progressive ratio session0.20.30.60.30.70.80.50.00.50.50.3
Distance traveled before self-admin1.31.45.20.70.91.32.30.10.71.30.8
Distance traveled after self-admin2.52.74.12.01.71.40.71.62.01.81.6
Delta time in closed arm before/after self-admin0.30.30.90.3-0.8-0.40.41.0-0.40.3-0.4
Delta time in open arm before/after self-admin0.30.31.1-0.11.00.50.3-0.50.50.30.6
Diff in mean of infusions in LGA sessions0.50.61.00.50.60.50.60.80.90.91.0
Extinction: sum of active levers before priming0.70.73.20.20.60.61.80.20.61.00.6
Active lever presses in extinction session 60.10.10.30.50.20.30.20.60.20.40.0
Delta distance traveled before/after self-admin0.91.03.91.00.0-0.6-2.01.50.7-0.00.3
Delta ambulatory time before/after self-admin1.31.43.71.50.4-0.2-1.71.91.10.50.7
Time in closed arm before self-admin3.03.47.80.62.72.81.2-0.52.11.51.8
Time in closed arm after self-admin0.40.41.30.90.10.5-0.51.10.30.5-0.2
Time in open arm before self-admin0.91.01.8-0.8-1.4-1.2-0.7-0.5-1.1-1.1-0.8
Time in open arm after self-admin0.80.92.7-1.6-0.1-0.5-0.1-1.6-0.7-1.0-0.3
Sum of active levers in priming session hrs 5-60.20.20.50.10.70.50.5-0.20.30.40.4
Time to tail flick, vehicle, before self-admin0.20.20.40.40.2-0.3-0.50.60.50.30.5
Time to tail flick, vehicle, after self-admin0.20.20.8-0.40.20.0-0.9-0.70.0-0.50.2
Time to tail flick, test, before self-admin0.10.10.5-0.0-0.30.20.7-0.1-0.20.10.0
Time to tail flick, test, after self-admin0.60.61.1-0.91.00.90.4-1.10.50.20.9
Delta time to tail flick, vehicle, before/after SA0.20.20.60.10.50.80.4-0.40.20.20.1
Delta time to tail flick, test, before/after SA1.21.02.7-1.61.20.6-0.3-1.60.5-0.21.0
Ambulatory time before self-admin1.01.03.80.00.91.12.0-0.40.61.00.9
Ambulatory time after self-admin2.12.34.11.21.91.40.50.92.01.62.0
Total heroin consumption0.20.30.70.30.10.40.80.60.50.80.4
Area under the delay curve2.22.46.00.51.41.52.50.31.41.81.7
Delay disc. indifference point, 0s delay0.40.41.51.20.20.50.20.90.30.5-0.5
Delay disc. indifference point, 16s delay3.33.36.90.52.01.82.6-0.01.92.02.3
Delay disc. indifference point, 2s delay1.71.97.90.70.81.22.80.50.81.70.9
Delay disc. indifference point, 24s delay1.21.23.00.50.70.50.81.01.31.41.7
Delay disc. indifference point, 4s delay1.81.93.41.01.21.51.80.81.41.81.2
Delay disc. indifference point, 8s delay2.22.24.40.21.71.52.1-0.11.41.61.9
Delay discount exponential model param2.22.35.9-0.4-1.4-1.4-2.4-0.2-1.4-1.8-1.7
Delay discount hyperbolic model param2.22.46.5-0.5-1.4-1.5-2.5-0.3-1.4-1.9-1.7
Fecal boli incidents, locomotor time 12.62.94.11.71.71.61.21.32.02.01.8
Change in fecal boli incidents, locomotor task1.61.53.0-1.1-1.6-1.7-1.2-0.2-1.2-1.2-0.8
Time >=10cm from walls, locomotor time 10.60.61.91.4-0.0-0.0-0.31.40.50.60.0
Bouts of movement, locomotor time 10.50.61.40.2-1.2-0.9-0.50.8-0.6-0.3-0.9
Total resting periods, locomotor time 10.30.31.10.6-0.7-0.3-0.01.0-0.20.2-0.5
Rest time, locomotor task time 10.60.61.91.30.00.40.41.40.50.9-0.1
Distance moved, locomotor task time 11.21.32.1-1.0-1.0-1.1-1.4-0.8-1.3-1.5-1.1
Vertical activity count, locomotor time 10.40.42.4-0.40.2-0.1-1.5-0.10.0-0.6-0.0
Time >=10cm from walls, locomotor time 20.20.30.50.60.40.3-0.40.60.70.50.4
Bouts of movement, locomotor time 20.40.41.0-0.5-0.7-0.70.6-0.2-0.9-0.4-1.0
Total resting periods, locomotor time 20.20.21.1-0.1-0.3-0.31.00.2-0.50.1-0.6
Rest time, locomotor task time 20.40.50.90.70.40.40.90.70.81.00.7
Distance moved, locomotor task time 21.01.22.0-0.5-1.1-1.0-1.4-0.4-1.2-1.3-1.3
Vertical activity count, locomotor time 20.30.31.60.2-0.3-0.4-1.30.5-0.2-0.5-0.5
Weight adjusted by age0.50.61.7-0.5-0.7-0.9-1.3-0.5-0.6-0.9-0.4
Seeking ratio, delayed vs. immediate footshock0.30.41.1-1.00.70.50.3-0.90.10.10.4
Locomotion in novel chamber1.92.39.5-2.60.6-0.0-0.3-3.1-0.5-1.20.5
Locomotion in novel chamber post-restriction0.40.51.6-0.90.30.31.3-1.1-0.20.10.3
Progressive ratio0.60.71.30.51.11.00.40.41.01.00.9
Food seeking constrained by brief footshock0.10.20.80.2-0.4-0.20.10.9-0.10.5-0.3
Seeking ratio, punishment vs. effort0.10.20.50.1-0.7-0.40.20.4-0.4-0.0-0.5
Run reversals in cocaine runway, females0.70.71.4-1.1-0.4-0.6-1.0-1.2-0.6-1.20.0
Run reversals in cocaine runway, males0.30.30.90.1-1.0-0.9-0.30.8-0.30.1-0.0
Latency to leave start box in cocaine runway1.51.73.6-0.4-1.6-1.3-0.7-0.4-1.6-1.5-1.9
Latency to leave start box in cocaine runway, F0.30.30.5-0.4-0.5-0.20.4-0.7-0.7-0.5-0.7
Latency to leave start box in cocaine runway, M2.82.75.2-0.3-2.1-1.8-1.40.0-1.9-1.8-2.3
Cd content in liver0.70.71.5-1.2-0.5-1.0-0.7-0.8-1.1-0.9-0.5
Co content in liver0.10.10.3-0.10.50.4-0.10.10.10.50.2
Cu content in liver1.61.92.8-1.21.71.41.6-1.70.91.01.4
Fe content in liver0.60.74.00.4-0.2-0.8-2.00.3-0.1-0.7-0.7
K content in liver0.50.51.10.70.60.81.0-0.10.80.60.4
Mg content in liver0.60.61.00.70.90.70.90.01.00.70.6
Mn content in liver0.50.61.0-0.8-1.0-0.70.3-0.7-1.0-0.7-0.7
Na content in liver0.70.72.0-0.41.41.10.2-0.80.90.41.0
Rb content in liver0.20.20.50.40.40.40.50.40.50.70.4
Se content in liver1.51.85.2-2.3-0.4-1.1-0.6-2.2-1.1-1.2-0.4
Sr content in liver1.11.03.0-1.50.60.61.1-1.7-0.20.10.8
Zn content in liver0.40.41.1-0.60.70.50.6-1.00.40.10.6