Hub : Genes

Ccdc107

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017253 0.09 0.06 1.2e-10 0.11 0.1 0.1 0.1 7.4e-12 9.2e-11 5.4e-11 3.5e-11
2 Adipose mRNA stability ENSRNOG00000017253 0.03 0.02 2.6e-04 0.03 0.03 0.03 0.03 2.4e-04 5.5e-04 3.1e-04 4.8e-04
3 Brain gene expression ENSRNOG00000017253 0.09 0.06 1.4e-06 0.09 0.07 0.05 0.08 1.7e-08 3.1e-07 1.4e-05 4.4e-08
4 Brain mRNA stability ENSRNOG00000017253 0.1 0.06 5.3e-11 0.11 0.13 0.12 0.12 3.0e-10 5.4e-12 1.3e-11 2.5e-11
5 Eye mRNA stability ENSRNOG00000017253 0.35 0.17 1.2e-03 0.13 0.04 0.16 -0 4.6e-03 8.0e-02 2.0e-03 3.9e-01
6 Liver alternative TSS ENSRNOT00000023411 0.08 0.09 2.0e-05 0.03 0.04 0.04 0.04 9.6e-05 3.2e-05 1.4e-05 1.2e-05
7 Liver alternative TSS ENSRNOT00000095061 0.08 0.09 3.1e-05 0.03 0.04 0.04 0.04 1.3e-04 4.4e-05 2.0e-05 1.8e-05
8 Liver gene expression ENSRNOG00000017253 0.26 0.12 0.0e+00 0.15 0.17 0.18 0.17 1.8e-16 5.3e-18 1.1e-19 1.6e-18
9 Liver isoform ratio ENSRNOT00000023411 0.03 0.02 3.0e-04 0.02 0.02 0.02 0.02 1.9e-03 1.3e-03 2.5e-03 1.1e-03
10 Liver isoform ratio ENSRNOT00000095061 0.03 0.02 4.4e-04 0.02 0.02 0.02 0.02 2.1e-03 1.2e-03 1.9e-03 1.3e-03
11 OFC mRNA stability ENSRNOG00000017253 0.19 0.12 1.2e-03 0.14 0.07 0.1 0.11 3.4e-04 8.9e-03 2.3e-03 1.5e-03
12 PL alternative TSS ENSRNOT00000023411 0.04 0.03 4.7e-03 0.02 0.01 0.01 0.01 1.1e-02 4.1e-02 6.1e-02 5.1e-02
13 PL alternative TSS ENSRNOT00000095061 0.04 0.03 5.1e-03 0.02 0.01 0.01 0.01 1.1e-02 4.4e-02 8.9e-02 5.5e-02
14 PL mRNA stability ENSRNOG00000017253 0.03 0.02 4.0e-03 0.02 0.01 0.02 0.01 1.7e-02 2.4e-02 1.4e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail3.09.812.0-3.53.5-2.73.12.7-3.13.0-2.8-3.43.23.0-3.23.23.2
BMI without tail6.413.316.6-3.53.5-3.83.84.1-3.73.7-3.7-3.83.73.5-3.23.23.8
Body weight4.016.818.5-3.83.8-4.04.34.2-4.14.1-4.3-4.14.23.6-4.34.34.2
Epididymis fat weight0.40.92.0-0.20.2-1.41.01.4-1.11.1-1.0-0.60.90.9-0.60.61.0
Glucose1.21.92.4-1.21.2-1.41.51.5-1.41.4-1.4-1.31.41.2-1.41.41.5
Heart weight0.71.02.1-0.80.8-1.11.01.3-1.01.0-1.4-0.90.90.7-0.90.91.0
Left kidney weight0.51.42.9-0.80.8-1.31.31.5-1.11.1-1.7-1.01.00.6-1.51.51.1
Right kidney weight0.00.10.20.1-0.1-0.40.10.5-0.10.1-0.5-0.0-0.1-0.20.3-0.3-0.0
Tail length2.47.311.5-2.12.1-3.32.93.4-3.03.0-3.0-2.62.72.6-1.91.92.8
Length with tail0.72.64.7-0.70.7-2.01.82.1-1.71.7-2.2-1.21.51.2-1.51.51.6
Length without tail0.40.91.51.2-1.21.0-0.9-1.01.0-1.00.61.2-1.0-1.20.2-0.2-1.1
Liver weight, left0.30.41.30.4-0.4-0.80.51.2-0.90.9-0.5-0.00.50.90.5-0.50.5
Liver weight, right0.20.41.11.0-1.00.3-0.4-0.20.4-0.40.30.8-0.5-0.60.8-0.8-0.5
Parametrial fat weight0.10.21.0-0.10.1-0.80.51.0-0.50.5-0.6-0.30.40.3-0.30.30.5
Retroperitoneal fat weight0.10.30.60.4-0.40.6-0.7-0.50.5-0.50.60.5-0.5-0.40.8-0.8-0.4
Intraocular pressure2.63.74.9-1.51.5-2.22.12.0-1.92.0-2.0-1.81.81.6-2.22.21.9
Extensor digitorum longus weight4.919.822.7-4.14.1-4.64.74.6-4.44.4-4.8-4.44.64.1-4.44.44.7
Soleus weight0.30.93.01.7-1.7-0.3-0.30.40.5-0.5-0.31.3-0.9-1.10.8-0.8-0.5
Tibialis anterior weight6.823.330.8-3.93.9-5.35.25.6-5.05.0-5.3-4.64.94.3-4.64.65.0
Tibia length0.20.71.91.4-1.4-0.1-0.30.50.3-0.30.11.0-0.6-0.91.1-1.1-0.6
Number of licking bursts4.75.66.5-2.32.3-2.32.42.5-2.52.5-2.3-2.52.52.5-2.12.12.5
Food consumed during 24 hour testing period0.60.71.5-0.50.5-1.01.01.2-0.80.8-1.0-0.60.80.7-0.60.60.9
Times rat made contact with spout0.40.51.0-1.01.0-0.30.60.6-0.40.4-0.3-0.80.80.6-0.90.90.5
Mean time between licks in bursts1.21.64.21.4-1.40.8-1.2-0.80.9-0.91.21.3-1.1-0.72.1-2.1-1.1
Mean num. licks in bursts2.32.83.51.3-1.31.8-1.7-1.81.9-1.91.81.6-1.7-1.71.3-1.3-1.8
Std. dev. time between licks in bursts0.60.71.20.8-0.80.7-0.8-0.90.7-0.70.80.8-0.8-0.61.1-1.1-0.7
Water consumed over 24 hours0.91.11.7-1.21.2-0.81.11.1-0.80.8-0.9-1.11.10.8-1.31.30.9
Indifference point 0 sec0.81.45.0-0.40.4-1.21.10.9-0.60.6-1.8-0.60.5-0.2-2.22.20.9
Indifference point AUC9.210.812.9-2.92.9-3.63.53.2-3.53.5-3.4-3.33.33.2-3.13.13.5
Indifference point function ln k2.84.04.51.9-1.92.1-2.1-2.02.1-2.12.12.1-2.1-2.01.7-1.7-2.1
Indifference point function log k2.84.04.51.9-1.92.1-2.1-2.02.1-2.12.12.1-2.1-2.01.7-1.7-2.1
Delay discounting total patch changes 0 sec1.42.26.7-0.80.8-1.51.51.3-1.01.0-2.1-1.00.90.2-2.62.61.2
Delay discounting total patch changes 12 sec3.34.37.2-2.02.0-1.82.21.7-1.91.9-2.2-2.12.01.6-2.72.72.1
Delay discounting total patch changes 18 sec0.91.21.9-0.80.8-1.21.21.0-1.21.2-1.4-1.01.00.9-1.31.31.2
Delay discounting total patch changes 24 sec3.44.37.0-1.81.8-2.22.21.8-1.91.9-2.4-2.02.01.5-2.62.62.1
Delay discounting total patch changes 6 sec4.06.110.5-2.02.0-2.52.62.1-2.22.3-3.0-2.32.11.6-3.23.22.5
Delay discounting time to switch 0 sec3.85.77.82.0-2.02.7-2.5-2.32.4-2.42.62.3-2.2-2.02.8-2.8-2.4
Delay discounting water rate 0 sec2.94.69.9-1.81.8-2.12.22.0-1.71.7-2.4-2.01.81.3-3.23.22.0
Delay discounting water rate 12 sec0.00.10.30.2-0.2-0.20.20.3-0.00.0-0.20.10.0-0.0-0.60.60.0
Delay discounting water rate 18 sec0.70.92.4-1.21.2-0.50.90.6-0.50.5-0.8-1.00.90.6-1.61.60.7
Delay discounting water rate 24 sec0.20.20.8-0.90.90.30.1-0.2-0.00.00.3-0.60.40.5-0.50.50.2
Delay discounting water rate 6 sec0.50.71.5-0.70.7-1.01.01.2-0.60.7-0.8-0.80.90.8-0.90.90.7
Locomotor activity0.00.00.1-0.10.1-0.00.00.2-0.10.1-0.2-0.20.0-0.00.1-0.10.0
Locomotor testing distance0.10.20.50.7-0.7-0.0-0.20.10.2-0.2-0.20.5-0.4-0.60.3-0.3-0.3
Locomotor testing rearing0.40.61.4-0.30.3-1.10.91.2-0.90.9-1.2-0.60.80.6-0.50.50.8
Light reinforcement 10.51.04.20.6-0.6-1.51.12.1-0.80.8-1.4-0.10.4-0.1-0.70.70.8
Light reinforcement 20.40.61.51.2-1.2-1.20.51.0-0.20.3-1.00.6-0.2-0.6-0.40.40.1
Reaction time number correct0.10.10.4-0.20.2-0.50.50.4-0.20.2-0.6-0.20.3-0.1-0.60.60.2
Reaction time mean minus median0.60.82.3-1.21.2-0.30.50.2-1.00.9-0.2-1.01.11.50.3-0.30.9
Reaction time mean minus median AUC1.11.53.1-1.51.5-0.91.00.8-1.41.4-0.8-1.41.51.8-0.30.31.4
Reaction time num false alarms0.10.10.4-0.70.7-0.10.1-0.2-0.30.3-0.3-0.50.30.20.1-0.10.2
Reaction time num false alarms AUC0.40.61.1-1.01.0-0.70.70.5-0.70.7-1.1-1.00.70.5-0.60.60.7
Reaction time trials correct on left0.10.10.4-0.20.2-0.50.50.4-0.20.2-0.6-0.20.3-0.1-0.60.60.2
Reaction time trials on left0.10.10.2-0.10.1-0.40.30.3-0.10.1-0.5-0.10.2-0.1-0.50.50.1
Reaction time mean1.52.15.30.8-0.81.7-1.6-1.51.0-1.11.91.1-1.0-0.52.3-2.3-1.2
Reaction time mean AUC1.72.35.40.8-0.81.9-1.7-1.61.2-1.22.01.1-1.1-0.62.3-2.3-1.3
Median of all reaction times3.44.68.31.7-1.72.4-2.3-2.01.9-1.92.51.9-1.9-1.52.9-2.9-2.0
Reaction time omissions1.72.34.01.4-1.41.5-1.7-1.41.2-1.21.61.5-1.5-1.12.0-2.0-1.4
Reaction time false alarm rate0.00.00.2-0.40.40.2-0.1-0.4-0.10.1-0.1-0.30.00.10.2-0.20.0
Reaction time premature initiation rate2.12.85.01.2-1.22.1-1.8-1.71.9-1.92.21.6-1.5-1.41.2-1.2-1.8
Reaction time premature initiations1.21.72.91.0-1.01.7-1.3-1.31.6-1.61.71.3-1.2-1.30.7-0.7-1.4
Std. dev. reaction times0.30.41.7-0.30.30.6-0.5-0.5-0.10.10.8-0.10.10.71.3-1.30.0
Reaction time trials completed0.10.10.2-0.10.1-0.40.30.3-0.10.1-0.5-0.10.2-0.1-0.50.50.1
Reaction time trials AUC0.10.10.3-0.10.1-0.40.30.3-0.10.1-0.4-0.20.2-0.1-0.50.50.1
Social response proportion3.23.57.41.7-1.71.7-2.0-1.51.4-1.52.11.8-1.7-1.12.7-2.7-1.9
Social responses0.50.71.2-0.60.6-1.10.81.1-1.11.1-0.9-0.80.80.9-0.10.10.8
Social time0.81.03.91.2-1.20.2-0.8-0.10.2-0.20.70.9-0.7-0.32.0-2.0-0.6
Conditioned locomotion0.10.10.40.2-0.20.00.0-0.00.3-0.3-0.30.2-0.3-0.6-0.60.6-0.1
Cocaine response after cond. corrected2.12.43.91.8-1.81.3-1.3-1.11.7-1.71.31.8-1.7-2.01.0-1.0-1.6
Cocaine response after cond. not corrected2.02.34.22.1-2.11.0-1.3-0.81.4-1.41.11.8-1.7-1.81.3-1.3-1.5
Cocaine response before conditioning0.60.71.2-0.50.5-1.00.91.1-1.01.0-0.9-0.70.91.1-0.30.30.8
Saline control response0.50.72.4-0.10.1-1.01.01.5-0.70.8-0.9-0.40.70.4-1.01.00.7
Condit. Reinf. active minus inactive responses0.80.91.1-1.11.1-0.91.00.9-0.90.9-1.0-1.01.10.9-0.90.91.0
Condit. Reinf. active-inactive response ratio0.20.30.6-0.80.8-0.20.40.1-0.40.4-0.3-0.60.50.5-0.60.60.4
Condit. Reinf. active responses2.43.44.2-1.71.7-2.01.91.8-1.91.9-2.0-1.91.91.8-1.51.51.9
Condit. Reinf. inactive responses3.03.74.7-1.81.8-2.01.92.0-2.02.0-2.1-2.02.12.2-1.41.42.1
Condit. Reinf. lever presses2.63.65.3-2.02.0-1.81.81.6-2.12.1-1.7-2.12.02.3-1.31.32.0
Condit. Reinf. lever reinforcers received2.84.04.9-1.91.9-2.22.12.0-2.12.1-2.2-2.02.12.1-1.61.62.1
Pavlov. Cond. lever latency2.83.85.62.0-2.01.8-1.9-1.72.2-2.11.62.1-2.2-2.41.3-1.3-2.1
Pavlov. Cond. magazine entry latency0.80.92.20.9-0.90.9-0.9-0.70.7-0.71.10.9-0.8-0.61.5-1.5-0.7
Pavlov. Cond. change in total contacts0.60.92.5-1.11.1-0.70.70.7-1.11.1-0.3-1.11.11.6-0.00.01.0
Pavlov. Cond. index score0.20.20.7-0.50.5-0.20.20.3-0.50.50.1-0.50.60.80.3-0.30.5
Pavlov. Cond. latency score0.30.41.0-0.80.8-0.30.40.4-0.70.7-0.1-0.70.81.00.0-0.00.7
Pavlov. Cond. lever contacts1.42.03.1-1.41.4-1.41.41.3-1.61.6-1.2-1.51.51.8-0.90.91.6
Pavlov. Cond. magazine entry number0.10.10.40.3-0.3-0.30.10.10.1-0.1-0.50.2-0.2-0.5-0.70.7-0.1
Pavlov. Cond. intertrial magazine entries0.60.81.5-0.90.9-0.81.00.8-0.70.7-1.1-0.90.80.6-1.21.20.8
Pavlov. Cond. lever-magazine prob. diff.0.20.20.7-0.50.5-0.20.20.2-0.50.50.1-0.40.50.80.4-0.40.5
Pavlov. Cond. response bias0.50.71.5-0.80.8-0.80.70.7-1.01.0-0.5-0.90.91.2-0.10.10.9
Conditioned reinforcement - actives0.50.51.1-1.11.1-0.30.6-0.1-0.40.4-0.5-0.90.60.3-1.01.00.7
Conditioned reinforcement - inactives0.10.10.30.0-0.00.3-0.1-0.20.4-0.40.00.2-0.2-0.5-0.20.2-0.2
Conditioned locomotion0.80.92.3-1.31.3-0.50.90.4-0.50.5-0.9-1.10.80.4-1.51.50.8
Intermittent access intake day 1-15 change0.50.51.2-0.80.8-0.40.70.7-0.80.8-0.0-0.71.01.1-0.40.40.8
Intermittent access intake escalation1.01.01.7-1.01.0-0.81.01.0-1.01.0-0.4-1.01.31.3-0.90.91.0
Intermittent access intake escalation 21.21.22.2-1.41.4-0.61.00.9-1.11.0-0.3-1.31.31.5-0.90.91.1
Intermitt. access day 1 inactive lever presses0.91.01.3-1.01.0-0.91.01.1-0.80.8-1.1-1.00.90.7-1.21.20.9
Intermitt. access day 15 inactive lever presses0.10.10.5-0.10.1-0.10.20.50.0-0.0-0.4-0.10.0-0.3-0.70.70.2
Intermitt. access escalation Index0.90.82.20.2-0.2-1.41.01.5-0.90.9-1.0-0.30.80.8-1.01.00.7
Intermittent access day 1 total infusions0.30.41.50.1-0.10.4-0.3-0.70.7-0.7-0.30.2-0.6-1.2-0.70.7-0.4
Intermittent access day 15 total infusions0.91.02.7-1.11.1-0.61.00.5-0.70.7-0.9-1.00.90.4-1.61.60.9
Intermittent access terminal intake (last 3 days)1.21.33.5-1.31.3-0.71.10.7-0.80.8-1.1-1.21.00.5-1.91.91.0
Intermittent access total infusions1.51.74.5-1.51.5-0.91.20.7-0.90.9-1.4-1.31.10.5-2.12.11.1
Intermittent access day 1 locomotion0.50.51.7-0.10.10.7-0.5-1.10.9-0.9-0.10.2-0.8-1.3-0.40.4-0.7
Intermittent access day 15 total locomotion0.50.51.4-0.00.01.0-0.5-1.11.0-1.00.20.3-0.7-1.2-0.50.5-0.7
Intermittent access total locomotion0.30.41.1-0.60.60.9-0.3-1.10.7-0.70.2-0.1-0.3-0.8-0.60.6-0.3
Intermittent access standard deviation0.40.50.7-0.80.8-0.30.60.6-0.70.6-0.6-0.70.70.5-0.80.80.8
Cocaine induced anxiety1.61.92.51.6-1.61.2-1.3-1.21.4-1.41.61.5-1.4-1.21.2-1.2-1.5
Post-drug Anxiety0.20.30.60.7-0.7-0.80.30.8-0.60.6-0.00.20.30.50.3-0.30.1
Baseline Anxiety1.61.62.7-1.31.3-1.31.31.2-1.61.5-1.2-1.41.41.6-0.50.51.3
Lifetime Intake1.51.64.7-1.21.2-1.01.20.8-0.80.8-1.7-1.20.90.1-2.22.21.0
Incentive Sensitization - Responses0.10.10.30.2-0.20.1-0.10.00.3-0.3-0.10.2-0.3-0.6-0.30.3-0.2
Incentive Sensitization - Breakpoint0.10.10.40.3-0.30.2-0.2-0.10.4-0.40.00.3-0.4-0.7-0.20.2-0.3
Progressive ratio test 1 active lever presses0.80.83.8-0.70.7-0.40.80.4-0.10.1-1.2-0.60.4-0.4-1.91.90.4
Progressive ratio test 1 breakpoint1.01.04.0-0.90.9-0.60.90.5-0.30.3-1.3-0.80.6-0.2-2.02.00.5
Progressive ratio test 1 inactive lever presses0.60.72.3-0.20.2-0.90.81.0-0.30.3-1.3-0.40.3-0.4-1.51.50.3
Progressive ratio test 2 active lever presses0.30.31.3-0.10.1-0.10.2-0.10.2-0.2-0.7-0.1-0.1-0.8-1.11.1-0.1
Progressive ratio test 2 breakpoint0.30.31.10.0-0.00.20.0-0.30.4-0.4-0.50.1-0.3-1.0-1.01.0-0.2
Progressive ratio test 2 inactive lever presses0.40.41.3-0.70.7-0.40.60.3-0.40.4-0.8-0.60.50.0-1.11.10.5
Total sessions with >9 infusions0.30.31.2-0.00.0-0.20.20.10.2-0.2-0.8-0.0-0.3-1.0-1.11.1-0.1
Short access day 1 total inactive lever presses2.73.06.2-1.71.7-1.61.71.8-1.21.3-2.1-1.71.50.9-2.52.51.3
Short access day 10 total inactive lever presses0.10.20.60.1-0.1-0.40.40.8-0.40.4-0.2-0.10.40.5-0.40.40.4
Short access day 1 total infusions1.61.74.2-1.11.1-1.31.21.3-0.80.8-1.9-1.10.80.1-2.12.10.9
Short access day 10 total infusions0.91.03.0-0.80.8-0.91.00.8-0.50.5-1.4-0.80.6-0.1-1.71.70.6
Short access total infusions0.50.62.0-0.40.4-0.60.60.5-0.20.2-1.3-0.50.1-0.6-1.41.40.2
Short access day 1 locomotion0.10.20.7-0.30.30.2-0.1-0.20.4-0.4-0.5-0.1-0.4-0.9-0.30.3-0.5
Short access day 10 total locomotion0.40.51.5-0.20.21.0-0.7-1.20.7-0.70.80.2-0.6-0.60.6-0.6-0.5
Short access total locomotion0.20.20.4-0.50.5-0.30.30.2-0.10.1-0.6-0.40.1-0.3-0.70.70.0
Compulsive drug intake0.30.30.8-0.10.1-0.80.70.3-0.70.7-0.9-0.30.60.7-0.50.50.5
One hour access (0.3 mA shock)0.81.02.6-0.80.8-1.01.00.4-0.70.7-1.3-0.90.80.3-1.61.60.8
One hour access (shock baseline)0.81.03.3-1.01.0-0.60.90.6-0.40.4-1.1-0.90.6-0.1-1.81.80.8
Number of responses in last shaping day0.30.31.10.6-0.6-0.60.31.0-0.10.1-1.00.2-0.2-0.7-0.70.7-0.1
Context. condit. distance diff. score0.10.10.2-0.00.00.4-0.3-0.40.3-0.30.50.1-0.2-0.2-0.10.1-0.2
Locomotion velocity, session 10.50.61.60.5-0.5-1.30.81.2-0.40.4-1.10.00.1-0.3-1.01.00.5
Locomotion distance, session 10.30.31.10.1-0.1-1.00.60.9-0.40.4-1.1-0.20.20.1-0.60.60.5
Locomotion velocity, session 23.03.54.8-1.91.9-1.91.81.6-2.12.1-1.7-2.01.92.2-1.41.42.0
Locomotion distance, session 21.52.14.2-0.60.6-2.01.62.1-1.71.7-1.9-1.11.31.3-0.80.81.6
Locomotion velocity, session 30.10.10.20.5-0.5-0.40.20.5-0.00.0-0.30.2-0.1-0.3-0.20.20.0
Locomotion distance, session 32.93.25.2-1.51.5-1.71.91.9-1.51.5-2.1-1.71.61.2-2.32.31.8
Stereotopy head waving bouts, day 30.40.41.61.3-1.30.0-0.40.00.3-0.30.30.9-0.7-0.70.5-0.5-0.5
Stereotopy head waving duration, day 30.60.71.61.3-1.30.4-0.7-0.40.6-0.60.71.0-0.9-0.80.8-0.8-0.7
Locomotion velocity, session 70.00.10.10.2-0.20.3-0.2-0.20.3-0.30.20.2-0.2-0.20.1-0.1-0.2
Locomotion distance, session 70.30.40.5-0.50.5-0.70.60.6-0.60.6-0.7-0.60.50.4-0.70.70.5
Stereotopy head waving bouts, day 72.52.93.9-1.51.5-1.71.81.8-1.61.6-1.8-1.61.71.4-2.02.01.8
Stereotopy head waving duration, day 70.40.51.1-0.30.3-1.00.81.1-0.70.7-0.8-0.50.70.7-0.60.60.8
Locomotion velocity, session 80.20.20.90.9-0.9-0.3-0.10.4-0.00.0-0.00.6-0.3-0.20.7-0.7-0.2
Locomotion distance, session 80.10.20.60.2-0.2-0.80.40.7-0.50.5-0.6-0.10.20.2-0.20.20.4
Degree of sensitization distance1.51.62.81.2-1.21.0-1.3-1.20.9-0.91.41.2-1.2-0.81.7-1.7-1.3
Degree of sensitization stereotypy1.71.92.9-1.41.4-1.31.41.3-1.11.1-1.4-1.41.41.1-1.71.71.4
Condit. Reinf. active minus inactive responses0.50.50.7-0.70.7-0.70.70.7-0.80.8-0.6-0.80.80.9-0.40.40.8
Condit. Reinf. active-inactive response ratio0.80.81.20.7-0.71.1-0.9-0.81.0-1.01.00.8-0.8-0.81.0-1.0-1.0
Condit. Reinf. active responses3.03.64.8-1.81.8-1.91.91.8-2.12.1-1.7-2.02.02.2-1.41.42.1
Condit. Reinf. inactive responses3.74.36.6-1.91.9-2.22.02.0-2.52.5-1.8-2.12.22.6-1.31.32.3
Incentive salience index mean4.65.66.3-2.12.1-2.52.52.4-2.52.5-2.4-2.42.42.4-2.02.02.5
Condit. Reinf. lever presses11.014.818.7-3.23.2-4.34.14.1-4.14.1-4.2-3.73.83.7-3.53.54.1
Time in familiar zone, hab. session 10.30.30.8-0.90.90.8-0.4-0.90.2-0.20.9-0.40.10.30.0-0.0-0.3
Time in novel zone, hab. session 13.33.27.02.6-2.60.9-1.5-0.81.6-1.61.02.3-1.9-1.91.9-1.9-1.5
Total zone transitions, hab. session 10.00.00.10.0-0.0-0.20.00.1-0.20.20.0-0.10.10.30.3-0.30.1
Total locomotion distance, hab. session 10.50.71.7-1.01.0-0.60.60.5-1.01.0-0.4-1.00.91.3-0.10.10.9
Locomotion velocity, hab. session 11.72.54.2-1.71.7-1.61.41.3-1.91.9-1.3-1.71.72.1-0.80.81.7
Time in familiar zone, hab. session 20.60.61.50.2-0.21.0-0.9-1.00.6-0.61.20.5-0.5-0.21.1-1.1-0.8
Time in novel zone, hab. session 21.51.63.01.6-1.60.9-1.0-0.81.4-1.40.71.5-1.4-1.70.6-0.6-1.2
Total zone transitions, hab. session 20.50.61.4-0.30.3-1.20.81.1-0.80.9-1.1-0.60.60.7-0.50.50.8
Total locomotion distance, hab. session 20.91.21.5-1.01.0-1.21.11.1-1.21.2-1.2-1.11.11.2-0.70.71.2
Locomotion velocity, hab. session 21.21.72.1-1.21.2-1.41.31.3-1.41.4-1.4-1.31.31.4-1.01.01.4
Novel to familiar place preference ratio3.84.06.12.2-2.21.9-1.9-1.82.2-2.21.72.3-2.2-2.51.4-1.4-2.0
Novelty place preference5.25.47.52.4-2.42.2-2.2-2.12.6-2.52.12.5-2.5-2.71.7-1.7-2.4
Time in novel zone, NPP test6.46.89.12.8-2.82.5-2.5-2.32.8-2.82.32.9-2.8-3.02.0-2.0-2.7
Total zone transitions, NPP test0.50.71.7-0.20.2-1.31.01.3-0.90.9-1.3-0.50.70.7-0.60.61.0
Total locomotion distance, NPP test2.12.94.6-1.31.3-2.11.81.9-1.71.7-2.2-1.51.61.5-1.81.81.8
Locomotion velocity, NPP test2.94.26.0-1.71.7-2.32.12.1-2.02.0-2.4-1.91.91.8-2.12.12.1
Pavlov. Cond. lever latency7.79.811.92.7-2.73.4-3.3-3.43.4-3.43.53.1-3.2-3.12.7-2.7-3.3
Pavlov. Cond. magazine entry latency0.40.50.8-0.60.6-0.80.70.7-0.90.9-0.7-0.70.70.9-0.10.10.8
Pavlov. Cond. change in total contacts2.72.93.6-1.51.5-1.81.81.9-1.81.8-1.9-1.71.71.6-1.51.51.8
Pavlov. Cond. index score3.24.15.4-1.81.8-2.22.12.1-2.32.3-2.1-2.12.12.2-1.31.32.2
Pavlov. Cond. latency score3.03.95.0-1.81.8-2.12.02.0-2.22.2-2.1-2.02.12.1-1.41.42.1
Pavlov. Cond. lever contacts6.17.29.0-2.52.5-2.82.82.7-2.82.8-3.0-2.72.72.6-2.42.42.8
Pavlov. Cond. magazine entry number0.70.91.20.8-0.81.0-0.9-1.01.1-1.10.91.0-1.0-1.10.5-0.5-1.1
Pavlov. Cond. intertrial magazine entries0.20.30.5-0.40.4-0.60.50.5-0.60.6-0.5-0.50.60.7-0.40.40.6
Pavlov. Cond. lever-magazine prob. diff.3.03.85.0-1.81.8-2.02.01.9-2.22.2-2.0-2.02.12.2-1.31.32.1
Pavlov. Cond. response bias3.34.05.0-1.81.8-2.22.12.1-2.22.2-2.1-2.02.12.1-1.51.52.2
Bone: apparent density1.52.42.8-1.71.7-1.31.61.4-1.51.5-1.5-1.71.61.5-1.71.71.6
Bone surface0.81.41.9-1.01.0-1.11.31.2-1.11.1-1.4-1.21.21.0-1.41.41.2
Bone volume0.81.41.7-1.11.1-1.01.21.1-1.11.1-1.2-1.21.21.1-1.31.31.1
Bone: connectivity density0.91.42.1-1.51.5-0.91.10.8-1.01.0-1.1-1.41.21.2-1.31.31.2
Bone: cortical apparent density0.10.10.4-0.40.40.5-0.3-0.40.2-0.20.6-0.10.00.30.4-0.4-0.2
Bone: cortical area2.23.44.1-1.91.9-1.61.81.9-1.91.9-1.7-2.02.02.0-1.51.51.9
Bone: cortical porosity0.50.50.80.7-0.70.7-0.7-0.90.7-0.70.90.7-0.7-0.60.6-0.6-0.6
Bone: cortical porosity0.00.00.1-0.10.10.00.1-0.2-0.00.00.0-0.10.0-0.0-0.30.30.1
Bone: cortical thickness0.91.52.8-1.71.7-0.61.11.0-1.01.0-0.9-1.51.41.3-1.21.21.1
Bone: cortical thickness0.20.20.40.2-0.20.7-0.4-0.30.5-0.50.60.3-0.3-0.30.5-0.5-0.5
Bone: cortical tissue density0.10.20.5-0.30.30.6-0.4-0.40.3-0.30.7-0.0-0.10.20.4-0.4-0.3
Bone: elastic displacement4.14.77.41.4-1.42.7-2.3-2.62.5-2.62.41.9-2.1-2.11.7-1.7-2.3
Bone: elastic work1.51.94.50.2-0.22.1-1.6-1.91.6-1.61.80.8-1.0-0.91.2-1.2-1.5
Bone: endosteal estimation0.81.83.3-0.70.7-1.71.51.8-1.51.6-1.7-1.01.31.2-1.01.01.4
Bone: endosteal perimeter0.91.93.5-0.70.7-1.81.61.9-1.51.6-1.8-1.11.31.1-1.21.21.4
Bone: final force0.91.42.4-1.01.0-1.31.31.5-1.31.3-1.3-1.21.31.3-0.60.61.3
Bone: final moment0.61.01.6-0.80.8-1.01.11.3-1.11.1-1.1-1.01.21.1-0.30.31.1
Bone: marrow area0.91.93.4-0.80.8-1.71.61.9-1.61.6-1.7-1.21.41.3-1.11.11.4
Bone: maximum diameter2.24.15.3-1.71.7-2.12.12.2-2.32.3-2.1-2.02.12.1-1.51.52.1
Bone: maximum force2.54.45.6-1.91.9-2.22.22.4-2.32.3-2.3-2.12.32.3-1.31.32.2
Bone: maximum moment1.93.24.2-1.71.7-1.81.92.0-2.02.0-1.9-1.92.02.0-1.01.01.9
Bone: minimum diameter0.00.00.0-0.10.10.2-0.1-0.2-0.10.10.2-0.1-0.00.10.2-0.2-0.1
Bone: periosteal estimation1.32.74.4-1.21.2-1.81.82.1-1.91.9-1.8-1.51.71.6-1.21.21.7
Bone: periosteal perimeter0.40.71.5-0.40.4-1.00.91.2-0.90.9-1.0-0.60.80.6-0.70.70.9
Bone: post-yield work1.21.73.0-0.60.6-1.71.41.6-1.61.6-1.7-1.11.21.3-0.80.81.4
Bone: stiffness3.14.97.2-1.71.7-2.52.32.7-2.72.7-2.3-2.12.42.5-1.01.02.4
Bone: tissue strength0.20.21.10.3-0.3-0.30.00.3-0.50.5-0.20.00.10.51.1-1.10.1
Bone: trabecular number1.52.33.0-1.71.7-1.41.51.2-1.61.6-1.3-1.71.61.7-1.31.31.6
Bone: trabecular spacing0.00.00.0-0.20.20.2-0.1-0.10.0-0.00.2-0.10.10.10.2-0.2-0.1
Bone: trabecular thickness0.00.00.20.1-0.10.2-0.3-0.50.1-0.10.30.1-0.20.00.2-0.2-0.2
Bone: trabecular tissue density1.92.74.8-0.90.9-2.11.72.2-2.12.1-1.7-1.41.71.9-0.60.61.7
Breakpoint value in progressive ratio session0.30.41.30.9-0.90.1-0.3-0.20.5-0.5-0.50.7-0.7-1.2-0.20.2-0.5
Distance traveled before self-admin4.44.78.2-1.41.4-2.62.32.9-2.22.2-2.6-1.82.01.7-2.32.32.0
Distance traveled after self-admin0.40.51.0-0.50.5-0.70.60.9-0.80.8-0.5-0.60.71.00.3-0.30.6
Delta time in closed arm before/after self-admin2.72.64.1-1.61.6-1.41.61.5-1.81.7-1.5-1.71.92.0-1.11.11.8
Delta time in open arm before/after self-admin0.50.51.00.9-0.90.6-0.7-0.50.7-0.70.40.8-0.8-1.00.5-0.5-0.7
Diff in mean of infusions in LGA sessions0.10.10.10.1-0.10.3-0.2-0.20.2-0.20.30.2-0.2-0.00.4-0.4-0.3
Extinction: sum of active levers before priming2.12.22.81.4-1.41.5-1.5-1.51.4-1.41.21.5-1.5-1.51.7-1.7-1.3
Active lever presses in extinction session 60.20.20.70.2-0.20.6-0.4-0.90.6-0.6-0.10.4-0.5-0.70.1-0.1-0.4
Delta distance traveled before/after self-admin1.31.43.51.0-1.01.0-1.1-0.90.9-1.01.31.0-1.0-0.51.9-1.9-1.1
Delta ambulatory time before/after self-admin2.83.06.51.5-1.51.6-1.8-1.51.5-1.52.01.6-1.5-1.02.6-2.6-1.6
Time in closed arm before self-admin2.22.54.11.0-1.01.8-1.7-2.01.8-1.81.91.3-1.7-1.71.1-1.1-1.7
Time in closed arm after self-admin0.10.10.50.1-0.10.5-0.3-0.50.3-0.30.70.2-0.20.00.3-0.3-0.3
Time in open arm before self-admin2.22.34.0-0.90.9-2.01.72.0-1.61.6-2.0-1.31.41.2-1.31.31.4
Time in open arm after self-admin1.51.73.3-1.01.0-1.41.31.4-1.11.2-1.8-1.21.10.7-1.61.61.2
Sum of active levers in priming session hrs 5-62.92.94.61.7-1.71.7-1.7-1.91.9-1.91.31.8-1.9-2.11.1-1.1-1.6
Time to tail flick, vehicle, before self-admin1.01.02.10.5-0.51.3-1.1-1.51.2-1.21.10.8-1.1-1.10.5-0.5-0.9
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.10.10.00.20.1-0.10.00.1-0.0-0.3-0.30.30.0
Time to tail flick, test, before self-admin0.40.40.7-0.80.8-0.50.60.2-0.50.5-0.3-0.80.70.7-0.80.80.6
Time to tail flick, test, after self-admin1.11.12.2-1.51.5-0.61.00.3-0.80.8-0.6-1.31.11.1-1.11.11.1
Delta time to tail flick, vehicle, before/after SA0.10.10.40.1-0.1-0.50.40.7-0.60.6-0.2-0.10.40.4-0.00.00.4
Delta time to tail flick, test, before/after SA0.00.00.1-0.20.20.4-0.2-0.20.3-0.30.1-0.0-0.1-0.20.0-0.0-0.0
Ambulatory time before self-admin3.63.86.7-1.31.3-2.32.12.5-1.81.9-2.6-1.61.71.2-2.32.31.8
Ambulatory time after self-admin0.10.10.4-0.10.1-0.50.30.6-0.40.4-0.6-0.20.20.30.3-0.30.3
Total heroin consumption0.40.51.60.9-0.90.5-0.6-0.20.8-0.8-0.00.8-0.9-1.30.2-0.2-0.8
Area under the delay curve0.40.41.00.6-0.60.6-0.6-0.60.7-0.70.00.6-0.8-1.00.5-0.5-0.7
Delay disc. indifference point, 0s delay1.41.52.61.4-1.41.2-1.2-1.11.2-1.20.81.3-1.4-1.61.1-1.1-1.3
Delay disc. indifference point, 16s delay1.11.13.01.0-1.00.8-0.9-0.71.4-1.30.21.1-1.3-1.70.3-0.3-1.3
Delay disc. indifference point, 2s delay0.00.00.2-0.40.40.10.1-0.1-0.10.1-0.1-0.30.20.3-0.00.00.2
Delay disc. indifference point, 24s delay0.20.20.50.4-0.40.4-0.5-0.30.4-0.40.40.4-0.4-0.40.7-0.7-0.4
Delay disc. indifference point, 4s delay0.10.10.1-0.00.00.3-0.3-0.30.3-0.3-0.10.1-0.3-0.30.3-0.3-0.2
Delay disc. indifference point, 8s delay0.00.00.2-0.30.3-0.10.10.1-0.20.2-0.5-0.20.10.00.0-0.00.1
Delay discount exponential model param0.30.30.8-0.50.5-0.50.50.5-0.60.60.1-0.50.70.9-0.30.30.6
Delay discount hyperbolic model param0.20.20.7-0.40.4-0.40.50.4-0.60.60.1-0.40.60.8-0.30.30.5
Fecal boli incidents, locomotor time 10.60.61.20.6-0.60.9-0.9-1.10.7-0.71.00.7-0.7-0.60.7-0.7-0.6
Change in fecal boli incidents, locomotor task1.11.02.0-0.50.5-1.31.11.2-0.90.9-1.1-0.80.80.6-1.41.40.7
Time >=10cm from walls, locomotor time 10.10.10.40.6-0.6-0.30.10.40.1-0.1-0.10.4-0.1-0.3-0.60.6-0.2
Bouts of movement, locomotor time 11.82.02.91.1-1.11.5-1.6-1.61.4-1.41.71.3-1.5-1.21.5-1.5-1.4
Total resting periods, locomotor time 12.42.64.31.2-1.21.8-1.8-1.91.5-1.62.11.4-1.6-1.31.8-1.8-1.5
Rest time, locomotor task time 11.82.04.80.3-0.31.7-1.5-1.91.0-1.12.20.8-1.0-0.12.1-2.1-1.0
Distance moved, locomotor task time 12.12.35.1-0.70.7-1.91.72.0-1.31.3-2.2-1.11.20.6-2.02.01.1
Vertical activity count, locomotor time 11.01.02.70.2-0.2-1.61.11.7-0.70.8-1.6-0.30.60.1-1.21.20.4
Time >=10cm from walls, locomotor time 20.10.10.2-0.10.1-0.30.30.4-0.40.4-0.3-0.20.20.2-0.10.10.4
Bouts of movement, locomotor time 20.70.81.0-1.01.0-0.90.80.8-0.90.9-0.9-1.00.80.9-0.60.61.0
Total resting periods, locomotor time 20.40.40.7-0.80.8-0.60.50.4-0.60.6-0.5-0.80.50.6-0.50.50.7
Rest time, locomotor task time 20.80.91.70.7-0.71.0-1.0-1.31.0-1.01.30.8-0.9-0.60.9-0.9-1.0
Distance moved, locomotor task time 20.30.40.8-0.70.7-0.50.50.7-0.80.8-0.4-0.70.70.90.2-0.20.5
Vertical activity count, locomotor time 20.30.31.2-0.10.1-0.80.61.1-0.70.7-0.7-0.40.50.50.1-0.10.4
Weight adjusted by age0.30.31.0-0.00.0-0.70.50.5-0.30.3-0.8-0.20.20.0-1.01.00.5
Seeking ratio, delayed vs. immediate footshock4.85.57.0-2.52.5-1.82.32.2-2.22.2-2.6-2.42.42.0-2.52.52.4
Locomotion in novel chamber0.10.10.3-0.60.60.30.0-0.5-0.10.10.0-0.40.20.20.1-0.10.0
Locomotion in novel chamber post-restriction1.72.03.5-1.81.8-1.11.31.0-1.61.5-1.0-1.71.71.9-0.70.71.4
Progressive ratio0.00.00.1-0.10.10.2-0.1-0.10.1-0.10.0-0.0-0.2-0.40.2-0.20.0
Food seeking constrained by brief footshock8.410.215.7-2.42.4-3.53.43.6-3.13.1-4.0-2.92.92.2-3.73.73.2
Seeking ratio, punishment vs. effort2.12.63.8-1.01.0-1.91.71.7-1.51.5-1.9-1.31.51.4-1.91.91.5
Run reversals in cocaine runway, females0.10.10.2-0.50.5-0.10.1-0.1-0.20.20.3-0.40.40.50.3-0.3-0.0
Run reversals in cocaine runway, males0.00.00.1-0.20.20.3-0.1-0.20.0-0.00.1-0.1-0.0-0.1-0.10.10.1
Latency to leave start box in cocaine runway0.70.81.1-1.01.0-0.70.90.9-0.80.8-0.6-1.01.01.0-0.90.90.8
Latency to leave start box in cocaine runway, F0.00.00.0-0.10.10.1-0.0-0.00.2-0.20.0-0.0-0.1-0.2-0.20.2-0.1
Latency to leave start box in cocaine runway, M1.31.22.3-0.70.7-1.41.21.5-1.11.1-1.1-1.01.11.0-1.21.20.9
Cd content in liver0.60.61.0-1.01.0-0.50.70.8-1.01.0-0.5-0.90.90.9-0.20.20.7
Co content in liver1.92.23.41.8-1.81.2-1.3-1.01.5-1.51.51.7-1.5-1.71.2-1.2-1.5
Cu content in liver1.72.03.51.4-1.41.4-1.4-1.21.2-1.21.71.4-1.2-0.91.9-1.9-1.4
Fe content in liver0.20.31.11.1-1.1-0.60.10.7-0.10.1-0.10.6-0.3-0.50.3-0.3-0.2
K content in liver0.30.30.60.8-0.80.3-0.5-0.20.5-0.50.40.7-0.7-0.80.5-0.5-0.6
Mg content in liver0.40.40.70.7-0.70.5-0.6-0.80.6-0.60.70.7-0.7-0.70.4-0.4-0.7
Mn content in liver0.20.20.7-0.50.5-0.40.40.2-0.50.5-0.1-0.50.60.8-0.10.10.5
Na content in liver2.83.05.51.9-1.91.4-1.6-1.11.3-1.31.71.8-1.6-1.32.4-2.4-1.7
Rb content in liver5.06.37.62.3-2.32.6-2.4-2.32.8-2.82.62.6-2.5-2.72.1-2.1-2.7
Se content in liver1.82.24.0-1.31.3-1.81.31.4-1.91.9-1.4-1.51.52.0-0.30.31.7
Sr content in liver0.80.71.5-0.40.4-1.10.70.7-1.21.2-1.0-0.70.81.1-0.30.30.9
Zn content in liver0.20.20.7-0.80.80.10.3-0.0-0.40.40.1-0.60.50.6-0.10.10.3