Lama1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017237 0.1 0.06 5.1e-04 0.03 0.02 0.02 0.03 5.9e-04 1.1e-03 1.5e-03 4.6e-04
2 BLA gene expression ENSRNOG00000017237 0.64 0.03 1.0e-12 0.22 0.21 0.21 0.21 5.1e-12 2.8e-11 1.8e-11 2.2e-11
3 Brain gene expression ENSRNOG00000017237 0.13 0.07 2.0e-08 0.1 0.08 0.08 0.09 3.5e-09 6.3e-08 3.2e-08 2.4e-08
4 Brain mRNA stability ENSRNOG00000017237 0.06 0.04 4.0e-04 0.04 0.03 0.03 0.03 1.1e-04 8.4e-04 6.1e-04 3.9e-04
5 IL gene expression ENSRNOG00000017237 0.26 0.14 9.0e-04 0.2 0.12 0.1 0.19 1.6e-05 6.6e-04 1.9e-03 2.4e-05
6 NAcc gene expression ENSRNOG00000017237 0.35 0.15 3.4e-09 0.13 0.02 0.11 0.03 1.3e-09 2.1e-02 1.1e-08 2.9e-03
7 PL gene expression ENSRNOG00000017237 0.23 0.11 4.2e-06 0.09 0.08 0.09 0.09 4.3e-07 1.7e-06 3.6e-07 1.5e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
BMI with tail2.78.89.42.83.12.9-3.02.93.03.0
BMI without tail2.34.95.42.02.32.2-2.32.22.32.2
Body weight3.916.717.14.04.14.1-4.14.04.14.1
Epididymis fat weight1.12.53.21.81.61.5-1.51.61.51.6
Glucose0.91.41.8-1.2-1.1-1.11.1-1.3-1.1-1.2
Heart weight1.52.13.01.31.31.6-1.41.71.41.4
Left kidney weight5.415.515.93.93.93.9-3.94.03.94.0
Right kidney weight8.925.326.25.05.05.0-5.05.15.05.0
Tail length0.20.60.90.80.80.9-0.80.90.80.8
Length with tail1.45.36.12.32.22.5-2.22.42.22.3
Length without tail1.22.73.01.71.61.7-1.61.61.61.6
Liver weight, left0.00.10.10.2-0.2-0.30.3-0.2-0.3-0.1
Liver weight, right0.00.00.00.10.10.0-0.10.10.10.1
Parametrial fat weight1.73.33.61.71.91.8-1.81.91.81.8
Retroperitoneal fat weight3.09.910.63.13.13.2-3.13.33.13.1
Intraocular pressure1.21.71.9-1.1-1.3-1.21.4-1.4-1.4-1.3
Extensor digitorum longus weight0.41.62.51.61.21.1-1.21.01.21.3
Soleus weight0.41.11.71.31.00.9-1.00.91.01.1
Tibialis anterior weight0.51.62.01.41.31.2-1.31.11.31.3
Tibia length3.510.010.53.23.23.1-3.23.03.23.2
Number of licking bursts0.10.10.20.20.30.4-0.30.30.30.3
Food consumed during 24 hour testing period0.10.10.3-0.5-0.2-0.20.2-0.2-0.2-0.3
Times rat made contact with spout0.00.00.1-0.30.1-0.0-0.10.10.1-0.0
Mean time between licks in bursts0.00.00.1-0.30.1-0.1-0.10.10.1-0.0
Mean num. licks in bursts0.00.00.0-0.20.0-0.1-0.00.00.0-0.0
Std. dev. time between licks in bursts0.00.10.2-0.4-0.2-0.20.2-0.2-0.2-0.2
Water consumed over 24 hours0.40.40.5-0.7-0.7-0.60.7-0.7-0.7-0.7
Indifference point 0 sec0.30.40.5-0.6-0.7-0.50.7-0.6-0.7-0.7
Indifference point AUC0.00.00.10.3-0.1-0.20.1-0.0-0.10.0
Indifference point function ln k1.92.74.3-2.1-1.5-1.51.5-1.6-1.5-1.7
Indifference point function log k1.92.74.3-2.1-1.5-1.51.5-1.6-1.5-1.7
Delay discounting total patch changes 0 sec0.30.50.6-0.6-0.8-0.60.8-0.6-0.8-0.7
Delay discounting total patch changes 12 sec0.10.10.2-0.1-0.4-0.30.4-0.2-0.4-0.3
Delay discounting total patch changes 18 sec0.00.00.20.5-0.1-0.20.1-0.0-0.10.1
Delay discounting total patch changes 24 sec1.92.33.81.91.41.5-1.41.51.41.6
Delay discounting total patch changes 6 sec0.10.20.30.1-0.6-0.50.6-0.4-0.6-0.4
Delay discounting time to switch 0 sec0.20.30.40.60.50.4-0.50.60.50.5
Delay discounting water rate 0 sec0.10.10.10.20.30.4-0.30.30.30.3
Delay discounting water rate 12 sec0.30.40.40.60.70.6-0.60.50.60.6
Delay discounting water rate 18 sec0.50.60.80.90.80.9-0.80.70.80.8
Delay discounting water rate 24 sec0.00.00.10.20.20.2-0.20.30.20.2
Delay discounting water rate 6 sec0.71.01.11.01.01.0-1.01.01.01.0
Locomotor activity0.00.10.10.10.20.3-0.30.30.30.2
Locomotor testing distance0.20.40.4-0.6-0.6-0.70.6-0.6-0.6-0.6
Locomotor testing rearing3.45.36.6-2.6-2.2-2.42.2-2.1-2.2-2.3
Light reinforcement 10.51.01.1-1.0-0.9-1.00.9-1.0-0.9-1.0
Light reinforcement 20.00.00.00.10.10.2-0.10.10.10.1
Reaction time number correct4.86.98.0-2.8-2.5-2.52.6-2.6-2.6-2.7
Reaction time mean minus median0.00.10.1-0.2-0.3-0.20.2-0.3-0.2-0.2
Reaction time mean minus median AUC1.01.31.5-1.1-1.2-1.11.1-1.2-1.1-1.1
Reaction time num false alarms1.82.53.51.91.51.5-1.51.61.51.6
Reaction time num false alarms AUC2.43.34.62.11.81.7-1.71.81.71.9
Reaction time trials correct on left4.86.98.0-2.8-2.5-2.52.6-2.6-2.6-2.7
Reaction time trials on left4.66.57.6-2.8-2.5-2.42.5-2.5-2.5-2.6
Reaction time mean0.10.10.2-0.3-0.3-0.40.4-0.5-0.4-0.4
Reaction time mean AUC0.50.70.9-0.7-0.8-0.80.9-0.9-0.9-0.8
Median of all reaction times0.10.10.2-0.3-0.3-0.40.4-0.4-0.4-0.3
Reaction time omissions0.00.10.10.10.30.2-0.30.10.30.2
Reaction time false alarm rate6.28.710.73.32.92.8-2.93.02.93.0
Reaction time premature initiation rate0.10.10.1-0.4-0.3-0.30.2-0.3-0.2-0.3
Reaction time premature initiations2.23.23.6-1.9-1.8-1.81.7-1.8-1.7-1.8
Std. dev. reaction times0.00.00.00.10.1-0.0-0.1-0.10.10.1
Reaction time trials completed4.66.57.6-2.8-2.5-2.42.5-2.5-2.5-2.6
Reaction time trials AUC3.75.36.4-2.5-2.2-2.22.3-2.3-2.3-2.4
Social response proportion0.40.40.7-0.3-0.8-0.60.8-0.6-0.8-0.6
Social responses0.30.40.5-0.7-0.7-0.60.7-0.7-0.7-0.7
Social time0.20.30.9-0.9-0.4-0.50.4-0.4-0.4-0.6
Conditioned locomotion1.72.02.31.11.51.5-1.51.51.51.4
Cocaine response after cond. corrected3.94.45.02.12.12.2-2.12.12.12.1
Cocaine response after cond. not corrected6.67.38.62.62.72.9-2.72.72.72.7
Cocaine response before conditioning0.50.70.90.50.80.9-0.80.90.80.7
Saline control response0.30.50.6-0.8-0.7-0.60.7-0.6-0.7-0.7
Condit. Reinf. active minus inactive responses1.82.32.81.11.61.6-1.61.71.61.4
Condit. Reinf. active-inactive response ratio3.73.94.41.82.02.0-2.02.12.02.0
Condit. Reinf. active responses0.40.50.8-0.00.80.8-0.80.90.80.6
Condit. Reinf. inactive responses0.91.12.5-1.6-0.9-0.90.9-0.9-0.9-1.1
Condit. Reinf. lever presses0.10.10.2-0.10.40.4-0.40.40.40.3
Condit. Reinf. lever reinforcers received0.40.50.8-0.00.80.8-0.80.90.80.6
Pavlov. Cond. lever latency0.20.30.5-0.1-0.6-0.70.6-0.6-0.6-0.4
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.1-0.20.1-0.2-0.1-0.1
Pavlov. Cond. change in total contacts0.00.00.1-0.20.10.2-0.10.20.1-0.0
Pavlov. Cond. index score0.00.00.0-0.20.10.2-0.10.10.1-0.0
Pavlov. Cond. latency score0.00.00.1-0.3-0.00.10.0-0.0-0.0-0.1
Pavlov. Cond. lever contacts0.00.10.1-0.20.20.3-0.20.20.20.1
Pavlov. Cond. magazine entry number0.10.10.10.10.20.4-0.20.30.20.2
Pavlov. Cond. intertrial magazine entries0.50.60.90.40.80.9-0.80.80.80.7
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.3-0.00.10.0-0.0-0.0-0.1
Pavlov. Cond. response bias0.10.10.3-0.5-0.2-0.20.2-0.2-0.2-0.3
Conditioned reinforcement - actives0.30.30.40.20.60.6-0.60.50.60.4
Conditioned reinforcement - inactives2.83.13.91.31.91.9-1.82.01.81.6
Conditioned locomotion1.82.12.3-1.5-1.4-1.41.5-1.5-1.5-1.5
Intermittent access intake day 1-15 change0.40.40.6-0.2-0.7-0.80.7-0.7-0.7-0.6
Intermittent access intake escalation0.30.30.5-0.3-0.6-0.70.6-0.6-0.6-0.5
Intermittent access intake escalation 20.10.10.10.2-0.3-0.30.3-0.2-0.3-0.2
Intermitt. access day 1 inactive lever presses2.32.42.91.41.61.6-1.51.71.51.5
Intermitt. access day 15 inactive lever presses6.87.58.72.42.82.9-2.73.02.72.7
Intermitt. access escalation Index0.00.00.20.40.10.0-0.10.00.10.2
Intermittent access day 1 total infusions0.10.10.2-0.10.50.4-0.40.40.40.2
Intermittent access day 15 total infusions0.10.10.20.20.40.2-0.30.30.30.3
Intermittent access terminal intake (last 3 days)0.10.10.3-0.5-0.2-0.40.3-0.3-0.3-0.4
Intermittent access total infusions0.30.30.50.30.70.6-0.60.60.60.5
Intermittent access day 1 locomotion0.30.30.40.30.70.6-0.60.50.60.5
Intermittent access day 15 total locomotion0.10.10.1-0.10.30.3-0.20.30.20.1
Intermittent access total locomotion0.20.20.30.10.50.5-0.40.40.40.3
Intermittent access standard deviation2.52.73.71.91.51.6-1.51.61.51.7
Cocaine induced anxiety0.10.10.2-0.4-0.3-0.40.3-0.3-0.3-0.3
Post-drug Anxiety0.10.10.2-0.4-0.2-0.20.2-0.2-0.2-0.2
Baseline Anxiety0.20.20.40.70.40.5-0.40.40.40.5
Lifetime Intake0.00.00.1-0.30.20.1-0.10.10.1-0.0
Incentive Sensitization - Responses0.10.10.1-0.2-0.4-0.30.3-0.4-0.3-0.3
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.2-0.20.2-0.2-0.2-0.2
Progressive ratio test 1 active lever presses0.90.91.20.41.11.0-1.01.01.00.8
Progressive ratio test 1 breakpoint0.70.71.00.41.00.9-0.90.90.90.8
Progressive ratio test 1 inactive lever presses0.30.30.50.30.60.7-0.60.70.60.5
Progressive ratio test 2 active lever presses0.20.20.4-0.6-0.3-0.30.3-0.4-0.3-0.4
Progressive ratio test 2 breakpoint0.00.00.1-0.3-0.1-0.20.1-0.2-0.1-0.2
Progressive ratio test 2 inactive lever presses1.71.92.31.01.41.5-1.41.51.41.3
Total sessions with >9 infusions0.70.71.4-1.2-0.7-0.70.8-0.8-0.8-0.9
Short access day 1 total inactive lever presses4.34.75.41.62.32.3-2.32.32.32.1
Short access day 10 total inactive lever presses2.83.13.41.71.71.8-1.71.91.71.7
Short access day 1 total infusions0.20.20.6-0.7-0.3-0.40.4-0.4-0.4-0.5
Short access day 10 total infusions0.60.71.1-1.0-0.6-0.80.8-0.8-0.8-0.9
Short access total infusions0.10.10.3-0.6-0.1-0.20.3-0.2-0.3-0.4
Short access day 1 locomotion2.42.63.1-1.8-1.4-1.61.6-1.7-1.6-1.6
Short access day 10 total locomotion0.00.00.1-0.10.30.2-0.30.10.30.1
Short access total locomotion0.30.30.5-0.7-0.4-0.40.5-0.6-0.5-0.5
Compulsive drug intake0.00.00.10.3-0.00.1-0.00.10.00.1
One hour access (0.3 mA shock)0.50.50.9-0.9-0.7-0.70.7-0.6-0.7-0.8
One hour access (shock baseline)0.40.50.7-0.9-0.5-0.70.6-0.6-0.6-0.7
Number of responses in last shaping day2.32.32.9-1.7-1.4-1.51.5-1.5-1.5-1.6
Context. condit. distance diff. score0.10.10.3-0.6-0.2-0.00.2-0.2-0.2-0.3
Locomotion velocity, session 10.70.80.8-0.9-0.9-0.90.9-0.8-0.9-0.9
Locomotion distance, session 10.81.01.41.20.91.0-0.91.00.91.0
Locomotion velocity, session 20.00.00.20.40.10.1-0.10.10.10.2
Locomotion distance, session 20.81.11.71.31.01.0-1.01.01.01.1
Locomotion velocity, session 31.01.21.4-1.2-1.1-1.11.1-1.0-1.1-1.1
Locomotion distance, session 30.50.50.60.50.80.8-0.80.80.80.7
Stereotopy head waving bouts, day 33.74.44.7-2.1-2.1-2.22.1-2.1-2.1-2.1
Stereotopy head waving duration, day 39.311.312.1-3.5-3.3-3.43.3-3.3-3.3-3.4
Locomotion velocity, session 70.50.50.60.60.70.8-0.70.70.70.7
Locomotion distance, session 71.82.32.71.21.61.6-1.61.51.61.5
Stereotopy head waving bouts, day 70.00.00.0-0.2-0.1-0.20.1-0.1-0.1-0.2
Stereotopy head waving duration, day 70.50.60.8-0.7-0.8-0.90.8-0.8-0.8-0.8
Locomotion velocity, session 80.30.40.5-0.5-0.6-0.60.6-0.7-0.6-0.6
Locomotion distance, session 80.00.00.1-0.10.20.3-0.20.20.20.1
Degree of sensitization distance0.30.30.30.60.50.6-0.50.50.50.6
Degree of sensitization stereotypy0.30.30.30.50.60.6-0.60.50.60.6
Condit. Reinf. active minus inactive responses1.92.12.31.21.51.4-1.51.51.51.4
Condit. Reinf. active-inactive response ratio2.83.03.11.61.81.7-1.81.71.81.7
Condit. Reinf. active responses1.41.72.01.21.41.2-1.41.41.41.3
Condit. Reinf. inactive responses0.20.30.3-0.4-0.5-0.60.5-0.4-0.5-0.5
Incentive salience index mean1.82.22.41.41.51.4-1.51.61.51.5
Condit. Reinf. lever presses0.10.10.20.50.40.2-0.40.40.40.4
Time in familiar zone, hab. session 14.44.24.3-2.0-2.0-2.02.0-2.1-2.0-2.0
Time in novel zone, hab. session 11.71.61.71.21.31.2-1.31.31.31.3
Total zone transitions, hab. session 10.10.10.10.30.30.2-0.30.30.30.3
Total locomotion distance, hab. session 12.33.33.61.61.91.8-1.91.91.91.8
Locomotion velocity, hab. session 11.01.51.71.11.31.2-1.31.31.31.2
Time in familiar zone, hab. session 21.81.92.4-1.3-1.3-1.51.3-1.4-1.3-1.3
Time in novel zone, hab. session 20.40.40.70.60.60.8-0.60.70.60.6
Total zone transitions, hab. session 20.10.10.20.30.40.4-0.40.40.40.4
Total locomotion distance, hab. session 22.02.62.81.41.71.6-1.71.71.71.6
Locomotion velocity, hab. session 22.73.63.91.72.01.9-2.02.02.01.9
Novel to familiar place preference ratio0.50.60.70.60.80.8-0.80.80.80.7
Novelty place preference0.40.50.60.50.70.8-0.70.70.70.6
Time in novel zone, NPP test0.30.30.40.40.50.6-0.50.60.50.5
Total zone transitions, NPP test0.60.91.10.80.91.0-0.91.00.90.9
Total locomotion distance, NPP test1.92.63.01.31.71.7-1.71.71.71.6
Locomotion velocity, NPP test2.23.23.61.51.81.9-1.81.91.81.7
Pavlov. Cond. lever latency1.01.21.8-1.3-1.1-1.01.1-1.1-1.1-1.2
Pavlov. Cond. magazine entry latency0.20.30.4-0.6-0.5-0.70.5-0.5-0.5-0.5
Pavlov. Cond. change in total contacts1.01.11.61.31.00.9-1.01.01.01.1
Pavlov. Cond. index score0.50.60.70.90.80.6-0.80.80.80.8
Pavlov. Cond. latency score0.81.01.11.11.00.9-1.01.01.01.0
Pavlov. Cond. lever contacts1.41.72.21.51.31.1-1.31.31.31.4
Pavlov. Cond. magazine entry number0.00.00.10.20.20.3-0.20.20.20.2
Pavlov. Cond. intertrial magazine entries1.11.41.41.11.21.1-1.21.11.21.2
Pavlov. Cond. lever-magazine prob. diff.0.30.30.50.70.60.4-0.60.50.60.6
Pavlov. Cond. response bias0.00.00.1-0.0-0.2-0.30.2-0.2-0.2-0.1
Bone: apparent density5.69.39.9-2.7-3.1-3.23.1-3.1-3.1-3.0
Bone surface4.58.08.6-2.6-2.9-2.82.9-2.9-2.9-2.8
Bone volume6.811.512.1-3.2-3.4-3.43.4-3.5-3.4-3.4
Bone: connectivity density2.94.65.6-1.7-2.2-2.42.2-2.2-2.2-2.1
Bone: cortical apparent density2.33.03.11.71.81.6-1.81.71.81.8
Bone: cortical area0.10.10.5-0.7-0.2-0.20.2-0.4-0.2-0.4
Bone: cortical porosity0.30.30.6-0.8-0.5-0.50.5-0.5-0.5-0.6
Bone: cortical porosity0.00.00.1-0.2-0.1-0.20.1-0.2-0.1-0.2
Bone: cortical thickness0.20.40.60.10.80.6-0.80.60.80.6
Bone: cortical thickness1.21.41.70.71.31.2-1.31.21.31.1
Bone: cortical tissue density2.73.53.61.91.91.7-1.91.81.91.9
Bone: elastic displacement0.30.30.40.30.60.6-0.60.60.60.5
Bone: elastic work0.00.00.1-0.3-0.1-0.10.1-0.2-0.1-0.2
Bone: endosteal estimation1.73.64.1-2.0-1.9-1.71.9-1.9-1.9-1.9
Bone: endosteal perimeter1.73.53.7-1.8-1.9-1.81.9-1.9-1.9-1.9
Bone: final force0.61.01.4-1.2-0.9-0.90.9-1.1-0.9-1.0
Bone: final moment0.50.81.2-1.1-0.9-0.80.9-1.0-0.9-0.9
Bone: marrow area1.53.33.6-1.9-1.8-1.61.8-1.8-1.8-1.9
Bone: maximum diameter0.51.01.3-1.1-0.9-1.00.9-1.1-0.9-1.0
Bone: maximum force0.20.30.6-0.8-0.4-0.40.4-0.6-0.4-0.5
Bone: maximum moment0.10.20.5-0.7-0.3-0.20.3-0.4-0.3-0.4
Bone: minimum diameter0.30.50.8-0.9-0.6-0.50.6-0.7-0.6-0.7
Bone: periosteal estimation1.02.02.9-1.7-1.3-1.31.3-1.5-1.3-1.5
Bone: periosteal perimeter1.62.63.6-1.9-1.6-1.41.6-1.6-1.6-1.7
Bone: post-yield work0.81.11.6-1.3-0.9-1.10.9-1.0-0.9-1.0
Bone: stiffness0.60.91.3-1.1-0.9-1.00.9-1.0-0.9-1.0
Bone: tissue strength1.01.01.1-0.9-1.0-0.91.0-1.1-1.0-1.0
Bone: trabecular number5.68.79.7-2.6-3.0-3.13.0-3.0-3.0-2.9
Bone: trabecular spacing1.41.71.81.31.41.3-1.41.31.41.3
Bone: trabecular thickness5.66.87.1-2.7-2.6-2.62.6-2.6-2.6-2.6
Bone: trabecular tissue density0.60.81.10.50.91.1-0.90.90.90.8
Breakpoint value in progressive ratio session1.41.61.81.11.31.2-1.31.11.31.3
Distance traveled before self-admin0.80.81.0-0.9-0.9-1.00.9-0.8-0.9-0.9
Distance traveled after self-admin0.00.00.1-0.30.1-0.30.0-0.1-0.0-0.1
Delta time in closed arm before/after self-admin0.80.71.21.10.70.9-0.80.90.80.9
Delta time in open arm before/after self-admin0.20.20.30.10.40.5-0.40.40.40.3
Diff in mean of infusions in LGA sessions0.70.81.4-0.6-0.9-1.00.9-1.2-0.9-0.8
Extinction: sum of active levers before priming1.01.01.31.10.91.1-1.00.91.01.0
Active lever presses in extinction session 62.72.62.81.71.61.6-1.71.31.71.7
Delta distance traveled before/after self-admin0.10.20.2-0.00.50.4-0.40.40.40.3
Delta ambulatory time before/after self-admin0.20.30.40.00.60.5-0.60.50.60.4
Time in closed arm before self-admin3.74.25.5-1.8-2.0-2.12.0-2.3-2.0-2.0
Time in closed arm after self-admin0.50.50.7-0.4-0.8-0.70.7-0.8-0.7-0.6
Time in open arm before self-admin0.10.10.30.30.20.4-0.10.50.10.2
Time in open arm after self-admin2.42.63.41.41.71.7-1.61.81.61.5
Sum of active levers in priming session hrs 5-61.11.11.51.21.00.9-1.01.01.01.1
Time to tail flick, vehicle, before self-admin1.61.62.0-1.0-1.3-1.21.3-1.4-1.3-1.2
Time to tail flick, vehicle, after self-admin0.50.50.8-0.2-0.8-0.90.7-0.8-0.7-0.6
Time to tail flick, test, before self-admin0.90.91.1-1.0-1.0-0.81.0-1.0-1.0-1.0
Time to tail flick, test, after self-admin0.60.60.9-0.9-0.7-0.90.6-0.9-0.6-0.7
Delta time to tail flick, vehicle, before/after SA0.40.40.50.70.60.5-0.70.60.70.7
Delta time to tail flick, test, before/after SA0.10.10.10.20.30.0-0.30.20.30.3
Ambulatory time before self-admin0.50.60.7-0.7-0.8-0.90.8-0.7-0.8-0.7
Ambulatory time after self-admin0.50.50.80.30.90.6-0.80.70.80.7
Total heroin consumption0.30.30.40.50.60.5-0.60.40.60.6
Area under the delay curve1.31.41.61.11.21.1-1.21.31.21.2
Delay disc. indifference point, 0s delay0.00.10.1-0.2-0.3-0.10.3-0.1-0.3-0.3
Delay disc. indifference point, 16s delay1.11.11.21.11.01.0-1.01.11.01.1
Delay disc. indifference point, 2s delay1.21.41.81.31.20.9-1.21.11.21.2
Delay disc. indifference point, 24s delay0.90.91.0-0.8-1.0-1.01.0-0.9-1.0-0.9
Delay disc. indifference point, 4s delay2.32.42.61.41.61.4-1.61.61.61.6
Delay disc. indifference point, 8s delay0.91.01.20.91.01.0-1.01.11.00.9
Delay discount exponential model param1.51.61.7-1.2-1.3-1.21.3-1.3-1.3-1.3
Delay discount hyperbolic model param1.81.92.1-1.3-1.4-1.31.4-1.4-1.4-1.4
Fecal boli incidents, locomotor time 10.20.20.50.70.30.5-0.30.50.30.4
Change in fecal boli incidents, locomotor task0.40.30.5-0.7-0.6-0.50.5-0.6-0.5-0.6
Time >=10cm from walls, locomotor time 10.80.80.9-0.9-0.9-1.00.9-0.9-0.9-0.9
Bouts of movement, locomotor time 10.00.00.1-0.20.10.0-0.10.10.1-0.0
Total resting periods, locomotor time 10.10.10.10.00.40.3-0.40.40.40.3
Rest time, locomotor task time 10.30.30.40.40.60.6-0.60.60.60.5
Distance moved, locomotor task time 11.41.51.7-1.1-1.3-1.21.3-1.1-1.3-1.3
Vertical activity count, locomotor time 11.11.21.4-1.2-1.1-0.91.1-1.0-1.1-1.1
Time >=10cm from walls, locomotor time 20.20.20.3-0.4-0.5-0.50.5-0.6-0.5-0.5
Bouts of movement, locomotor time 22.02.12.3-1.5-1.4-1.51.4-1.5-1.4-1.5
Total resting periods, locomotor time 20.91.01.1-1.1-1.0-1.00.9-1.0-0.9-1.0
Rest time, locomotor task time 20.20.20.50.20.50.7-0.50.60.50.4
Distance moved, locomotor task time 21.11.31.4-1.1-1.1-1.21.1-1.2-1.1-1.1
Vertical activity count, locomotor time 21.41.61.7-1.3-1.3-1.21.3-1.2-1.3-1.3
Weight adjusted by age0.20.20.4-0.4-0.4-0.60.4-0.6-0.4-0.4
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.4-0.10.30.00.2-0.0-0.1
Locomotion in novel chamber2.93.53.81.91.91.9-1.91.81.91.9
Locomotion in novel chamber post-restriction0.20.20.30.50.50.4-0.40.40.40.5
Progressive ratio1.92.22.5-1.1-1.5-1.61.6-1.6-1.6-1.4
Food seeking constrained by brief footshock0.70.91.1-0.9-0.9-1.00.9-1.0-0.9-0.9
Seeking ratio, punishment vs. effort0.60.80.90.70.90.9-1.00.91.00.9
Run reversals in cocaine runway, females0.00.00.0-0.2-0.10.00.10.1-0.1-0.1
Run reversals in cocaine runway, males0.40.40.4-0.6-0.7-0.60.7-0.6-0.7-0.6
Latency to leave start box in cocaine runway0.00.00.00.10.20.1-0.10.10.10.1
Latency to leave start box in cocaine runway, F1.11.21.4-1.0-1.1-1.11.2-1.1-1.2-1.1
Latency to leave start box in cocaine runway, M5.04.85.02.02.22.2-2.22.22.22.2
Cd content in liver0.91.01.01.01.01.0-1.01.01.01.0
Co content in liver0.50.60.70.40.90.8-0.90.80.90.7
Cu content in liver1.61.92.31.51.31.5-1.31.31.31.4
Fe content in liver1.61.92.6-1.6-1.3-1.41.3-1.3-1.3-1.4
K content in liver0.10.10.10.20.30.0-0.30.20.30.3
Mg content in liver0.00.00.1-0.10.20.1-0.20.10.20.1
Mn content in liver3.03.44.1-2.0-1.8-1.71.8-1.7-1.8-1.9
Na content in liver0.60.61.0-0.7-0.7-1.00.7-0.9-0.7-0.7
Rb content in liver0.60.81.21.10.90.8-0.90.70.90.9
Se content in liver0.20.30.6-0.8-0.4-0.50.4-0.4-0.4-0.5
Sr content in liver0.10.10.1-0.0-0.4-0.30.4-0.3-0.4-0.3
Zn content in liver0.60.70.80.90.90.8-0.90.70.90.9