Hub : Genes

Afap1l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017164 0.04 0.03 9.1e-05 0.03 0.03 0.03 0 2.3e-04 2.9e-04 7.6e-04 9.9e-02
2 Adipose mRNA stability ENSRNOG00000017164 0.03 0.02 1.0e-03 0.01 0.02 0.03 0.02 3.8e-02 1.3e-03 6.3e-04 6.2e-03
3 Brain gene expression ENSRNOG00000017164 0.21 0.09 0.0e+00 0.14 0.19 0.22 0.22 1.2e-12 1.4e-17 7.2e-20 2.2e-20
4 Brain mRNA stability ENSRNOG00000017164 0.56 0.13 0.0e+00 0.41 0.44 0.44 0.43 6.2e-41 2.6e-44 4.7e-44 8.3e-44
5 IL mRNA stability ENSRNOG00000017164 0.39 0.24 1.1e-04 0.23 0.18 0.17 0.22 3.5e-06 3.3e-05 7.4e-05 5.0e-06
6 LHb mRNA stability ENSRNOG00000017164 0.46 0.18 2.3e-07 0.29 0.25 0.28 0.27 1.2e-07 1.1e-06 1.7e-07 4.0e-07
7 Liver mRNA stability ENSRNOG00000017164 0.02 0.02 6.8e-03 0.01 0.01 0 0.01 1.2e-02 3.4e-02 3.2e-01 2.5e-02
8 NAcc gene expression ENSRNOG00000017164 0.1 0.05 1.7e-05 0.02 0.05 0.04 0.03 1.9e-02 2.4e-04 1.2e-03 3.9e-03
9 NAcc mRNA stability ENSRNOG00000017164 0.09 0.05 1.1e-05 0.03 0.06 0.05 0.04 1.5e-03 3.4e-05 2.3e-04 8.7e-04
10 OFC mRNA stability ENSRNOG00000017164 0.55 0.18 2.4e-07 0.16 0.3 0.33 0.31 1.5e-04 6.4e-08 1.3e-08 3.9e-08
11 PL mRNA stability ENSRNOG00000017164 0.2 0.11 8.9e-09 0.09 0.1 0.1 0.1 1.3e-07 5.4e-08 4.3e-08 3.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail8.728.336.44.15.7-6.0-5.6-5.3-5.1-5.8-4.3-5.4-5.7-5.2
BMI without tail3.98.112.11.83.0-3.5-2.9-2.6-2.6-2.9-2.7-3.2-3.1-2.6
Body weight8.837.246.84.96.5-6.8-6.4-6.2-5.8-6.6-4.8-6.0-6.6-6.0
Epididymis fat weight13.030.339.44.25.5-6.3-5.8-5.7-5.2-5.8-4.6-5.5-5.9-5.8
Glucose4.36.68.41.42.5-2.7-2.8-2.8-2.7-2.9-2.1-2.5-2.9-2.7
Heart weight2.84.15.11.82.2-2.0-2.1-2.2-2.2-2.2-1.2-1.8-2.0-2.2
Left kidney weight1.44.017.14.12.3-0.7-1.3-2.1-2.0-2.11.40.1-1.1-1.8
Right kidney weight4.512.828.35.34.2-2.9-3.3-3.9-3.7-4.2-0.1-1.7-3.4-3.8
Tail length0.10.30.7-0.20.2-0.7-0.5-0.4-0.4-0.4-0.8-0.7-0.6-0.3
Length with tail1.76.38.02.32.5-2.5-2.7-2.8-2.6-2.7-1.7-2.2-2.7-2.6
Length without tail4.610.113.22.83.2-3.0-3.5-3.6-3.3-3.6-1.9-2.6-3.4-3.5
Liver weight, left3.35.46.81.42.3-2.5-2.5-2.3-2.4-2.3-2.1-2.6-2.6-2.1
Liver weight, right6.310.412.52.83.5-3.5-3.4-3.3-3.1-3.4-2.5-3.2-3.4-3.1
Parametrial fat weight9.819.225.61.94.1-5.1-4.7-4.5-4.0-4.3-4.6-5.0-5.0-4.3
Retroperitoneal fat weight12.641.653.25.36.8-7.3-6.8-6.6-6.1-6.8-5.2-6.5-6.9-6.3
Intraocular pressure5.27.39.60.72.4-2.7-3.0-2.9-2.9-2.7-2.7-2.9-3.1-2.8
Extensor digitorum longus weight0.62.34.40.21.4-2.1-1.5-1.1-1.0-1.7-1.9-1.9-1.7-1.3
Soleus weight3.510.217.84.23.8-3.5-3.1-3.1-3.0-3.3-1.3-2.5-3.2-3.1
Tibialis anterior weight0.41.32.70.31.1-1.6-1.1-0.9-0.2-1.4-1.4-1.4-1.3-0.9
Tibia length1.33.65.42.02.3-1.2-2.0-2.2-2.2-2.2-0.6-1.4-1.8-2.1
Number of licking bursts0.30.31.3-0.70.1-0.6-0.4-0.2-0.4-0.2-1.1-0.8-0.5-0.2
Food consumed during 24 hour testing period0.91.12.1-1.4-1.40.91.00.90.21.20.50.91.01.1
Times rat made contact with spout0.10.10.30.60.20.1-0.2-0.2-0.6-0.10.30.1-0.1-0.2
Mean time between licks in bursts0.10.20.9-1.0-0.8-0.20.10.20.00.5-0.5-0.10.10.2
Mean num. licks in bursts0.40.51.91.40.30.60.0-0.3-0.3-0.21.30.80.2-0.3
Std. dev. time between licks in bursts0.10.20.6-0.5-0.50.30.30.30.80.3-0.00.30.40.3
Water consumed over 24 hours0.10.10.40.50.10.40.10.0-0.30.00.60.40.20.1
Indifference point 0 sec5.08.010.82.43.0-2.7-3.0-2.7-2.6-3.3-2.4-2.9-3.1-2.8
Indifference point AUC1.11.22.30.41.1-1.3-1.2-1.1-0.5-1.1-1.3-1.4-1.5-0.9
Indifference point function ln k0.10.10.3-0.2-0.40.60.20.1-0.30.00.50.50.2-0.3
Indifference point function log k0.10.10.3-0.2-0.40.60.20.1-0.30.00.50.50.2-0.3
Delay discounting total patch changes 0 sec4.97.910.42.33.0-2.7-3.0-2.7-2.6-3.2-2.5-3.0-3.2-2.7
Delay discounting total patch changes 12 sec1.82.44.21.01.7-1.9-1.5-1.2-0.8-1.7-1.9-2.0-1.8-1.0
Delay discounting total patch changes 18 sec4.86.39.41.12.5-2.7-2.6-2.4-2.0-2.6-2.8-3.0-3.1-2.2
Delay discounting total patch changes 24 sec3.74.67.91.02.3-2.4-2.2-1.8-1.4-2.3-2.6-2.8-2.5-1.6
Delay discounting total patch changes 6 sec6.49.813.42.03.2-3.3-3.3-3.1-2.9-3.4-3.0-3.4-3.7-2.9
Delay discounting time to switch 0 sec0.81.21.9-0.3-0.90.81.21.21.11.30.91.01.41.3
Delay discounting water rate 0 sec1.01.52.80.51.3-0.9-1.4-1.3-1.2-1.7-1.0-1.2-1.5-1.3
Delay discounting water rate 12 sec2.53.75.40.11.7-2.2-2.1-1.9-1.2-2.1-2.3-2.3-2.3-1.9
Delay discounting water rate 18 sec0.70.91.41.01.0-0.6-1.0-1.0-1.1-1.2-0.2-0.5-0.9-1.1
Delay discounting water rate 24 sec0.91.22.11.21.4-0.9-1.1-1.2-1.0-1.4-0.4-0.8-1.1-1.2
Delay discounting water rate 6 sec0.40.71.70.81.2-0.4-0.7-0.7-0.6-1.3-0.2-0.5-0.9-0.8
Locomotor activity1.11.83.11.31.5-0.8-1.4-1.4-1.8-1.7-0.4-0.9-1.4-1.4
Locomotor testing distance1.32.24.51.81.8-0.5-1.4-1.6-2.1-1.90.2-0.6-1.4-1.6
Locomotor testing rearing0.40.71.71.21.0-0.3-0.6-0.8-1.3-0.90.1-0.3-0.8-0.8
Light reinforcement 11.83.34.0-1.7-1.82.02.02.01.91.71.31.72.01.8
Light reinforcement 23.03.95.1-1.3-1.91.92.11.92.31.81.92.12.22.1
Reaction time number correct1.01.42.30.41.3-1.5-1.2-1.0-0.9-1.2-1.2-1.4-1.4-1.0
Reaction time mean minus median0.60.71.70.91.0-0.4-0.9-0.9-1.3-0.5-0.3-0.7-1.0-0.9
Reaction time mean minus median AUC0.40.62.11.51.0-0.0-0.6-0.7-1.0-0.30.3-0.2-0.6-0.7
Reaction time num false alarms0.10.10.60.80.3-0.30.0-0.00.3-0.20.20.10.30.1
Reaction time num false alarms AUC0.10.11.01.00.4-0.2-0.0-0.10.1-0.20.40.20.20.0
Reaction time trials correct on left1.01.42.30.41.3-1.5-1.2-1.0-0.9-1.2-1.2-1.4-1.4-1.0
Reaction time trials on left1.11.52.50.41.4-1.6-1.3-1.1-0.9-1.2-1.2-1.5-1.5-1.1
Reaction time mean0.50.71.61.31.0-0.5-0.8-0.8-1.1-0.5-0.1-0.5-0.8-0.9
Reaction time mean AUC0.20.20.90.90.6-0.1-0.4-0.4-0.6-0.10.1-0.2-0.4-0.5
Median of all reaction times0.40.51.71.30.9-0.4-0.7-0.7-0.8-0.50.1-0.3-0.6-0.8
Reaction time omissions0.50.71.00.90.8-1.0-0.9-1.0-0.5-0.4-0.7-1.0-0.9-0.9
Reaction time false alarm rate0.20.30.90.5-0.40.50.50.40.60.40.70.70.90.6
Reaction time premature initiation rate0.40.61.91.40.80.2-0.4-0.8-0.7-0.60.80.3-0.4-1.0
Reaction time premature initiations1.11.52.71.61.6-0.6-1.1-1.5-1.3-1.30.2-0.5-1.2-1.7
Std. dev. reaction times2.02.74.41.91.8-1.4-1.7-1.8-2.1-1.4-0.8-1.4-1.8-1.8
Reaction time trials completed1.11.52.50.41.4-1.6-1.3-1.1-0.9-1.2-1.2-1.5-1.5-1.1
Reaction time trials AUC1.21.72.70.51.4-1.6-1.3-1.2-1.0-1.3-1.2-1.5-1.5-1.1
Social response proportion1.41.64.22.01.5-0.5-1.2-1.5-1.5-1.40.5-0.3-0.9-1.4
Social responses5.36.88.72.02.8-2.5-2.8-2.7-3.0-2.7-1.8-2.5-2.8-2.9
Social time1.31.83.61.91.7-1.0-1.3-1.5-1.6-1.4-0.1-0.8-1.1-1.3
Conditioned locomotion0.10.10.40.0-0.20.60.40.30.20.10.60.50.30.3
Cocaine response after cond. corrected2.32.65.50.3-1.02.01.61.31.31.52.42.11.81.4
Cocaine response after cond. not corrected2.83.15.0-0.3-1.42.11.91.51.61.72.22.21.91.6
Cocaine response before conditioning0.30.42.1-1.5-0.8-0.10.30.40.50.5-0.7-0.2-0.00.3
Saline control response0.10.20.50.20.30.7-0.0-0.4-0.3-0.60.70.4-0.2-0.2
Condit. Reinf. active minus inactive responses3.03.77.0-0.61.1-1.7-2.1-2.0-1.9-1.6-2.6-2.4-2.2-2.0
Condit. Reinf. active-inactive response ratio1.11.12.5-0.60.5-0.8-1.1-1.2-0.8-0.5-1.6-1.4-1.2-1.2
Condit. Reinf. active responses4.66.510.30.11.9-2.6-2.8-2.5-2.6-2.4-3.2-3.1-2.9-2.4
Condit. Reinf. inactive responses1.82.23.20.51.3-1.7-1.6-1.2-1.7-1.6-1.8-1.8-1.6-1.1
Condit. Reinf. lever presses0.60.92.20.10.7-0.9-0.9-0.6-0.8-0.8-1.5-1.4-1.1-0.6
Condit. Reinf. lever reinforcers received3.24.47.4-0.11.5-2.1-2.3-2.1-2.2-1.9-2.7-2.6-2.4-2.0
Pavlov. Cond. lever latency0.50.61.7-0.1-0.60.90.80.50.50.81.31.10.90.4
Pavlov. Cond. magazine entry latency0.40.51.00.20.6-0.9-0.7-0.5-0.7-0.5-1.0-1.0-0.7-0.6
Pavlov. Cond. change in total contacts1.01.42.40.10.8-1.2-1.3-1.0-1.2-1.1-1.5-1.4-1.5-1.0
Pavlov. Cond. index score1.01.31.90.41.0-1.2-1.3-1.0-1.2-1.2-1.4-1.4-1.4-1.0
Pavlov. Cond. latency score0.91.11.80.30.9-1.2-1.1-0.8-1.0-1.1-1.3-1.3-1.3-0.9
Pavlov. Cond. lever contacts0.40.50.90.50.7-0.6-0.8-0.5-0.6-0.8-0.9-0.9-0.9-0.5
Pavlov. Cond. magazine entry number0.30.40.8-0.3-0.60.90.60.40.70.40.90.90.70.5
Pavlov. Cond. intertrial magazine entries0.10.10.20.00.2-0.5-0.2-0.1-0.2-0.1-0.5-0.5-0.3-0.1
Pavlov. Cond. lever-magazine prob. diff.1.01.21.70.51.0-1.1-1.2-1.0-1.2-1.1-1.2-1.3-1.3-1.0
Pavlov. Cond. response bias0.60.91.50.40.8-1.0-1.0-0.7-0.9-0.9-1.2-1.2-1.1-0.7
Conditioned reinforcement - actives0.60.62.70.8-0.11.00.50.10.10.21.61.20.70.4
Conditioned reinforcement - inactives0.30.41.10.90.5-0.6-0.6-0.6-1.1-0.5-0.1-0.3-0.4-0.5
Conditioned locomotion0.50.72.30.4-0.41.00.60.20.40.31.51.30.90.6
Intermittent access intake day 1-15 change2.12.14.40.91.5-1.2-1.6-1.3-2.1-1.3-1.2-1.6-1.7-1.2
Intermittent access intake escalation2.22.25.61.61.7-1.0-1.5-1.4-2.4-1.3-0.4-1.1-1.5-1.4
Intermittent access intake escalation 20.70.72.11.21.0-0.3-0.7-0.7-1.5-0.70.2-0.3-0.6-0.7
Intermitt. access day 1 inactive lever presses2.22.43.80.61.4-1.9-1.6-1.4-1.2-1.4-1.8-1.9-1.8-1.3
Intermitt. access day 15 inactive lever presses0.10.10.30.10.3-0.3-0.3-0.2-0.5-0.1-0.2-0.3-0.5-0.4
Intermitt. access escalation Index0.40.40.70.3-0.60.50.70.70.20.70.70.70.80.8
Intermittent access day 1 total infusions0.10.10.40.60.5-0.2-0.1-0.2-0.0-0.40.20.00.0-0.0
Intermittent access day 15 total infusions0.50.61.51.21.1-0.4-0.6-0.6-1.2-0.60.2-0.4-0.6-0.4
Intermittent access terminal intake (last 3 days)0.20.30.80.90.9-0.1-0.4-0.4-0.8-0.50.2-0.2-0.3-0.2
Intermittent access total infusions0.80.91.91.41.4-0.5-0.9-1.0-1.2-1.00.2-0.4-0.8-0.8
Intermittent access day 1 locomotion0.30.31.10.90.40.40.30.10.40.01.00.60.40.5
Intermittent access day 15 total locomotion2.83.05.00.92.0-1.5-1.9-1.8-2.2-1.7-1.3-1.8-2.0-1.5
Intermittent access total locomotion0.60.72.31.51.3-0.0-0.6-0.9-0.8-0.80.7-0.1-0.5-0.5
Intermittent access standard deviation0.70.71.40.50.8-1.2-0.8-0.6-0.9-0.8-1.0-1.1-1.0-0.6
Cocaine induced anxiety7.78.810.5-1.9-3.13.13.23.13.03.02.73.23.23.0
Post-drug Anxiety2.22.43.0-1.3-1.61.71.71.71.51.51.41.71.61.4
Baseline Anxiety7.47.810.11.32.8-2.9-3.0-2.7-3.0-2.7-2.7-3.1-3.2-2.9
Lifetime Intake0.91.02.11.51.4-0.5-0.9-1.1-1.2-1.10.3-0.4-0.9-0.9
Incentive Sensitization - Responses2.22.23.61.51.9-1.6-1.5-1.5-1.6-1.3-0.8-1.5-1.6-1.2
Incentive Sensitization - Breakpoint2.42.43.71.41.9-1.7-1.6-1.5-1.7-1.4-1.0-1.6-1.8-1.2
Progressive ratio test 1 active lever presses0.40.41.20.70.90.2-0.5-0.6-1.1-0.70.50.1-0.3-0.6
Progressive ratio test 1 breakpoint0.20.20.50.30.60.3-0.3-0.5-0.7-0.60.40.0-0.2-0.4
Progressive ratio test 1 inactive lever presses0.20.20.4-0.1-0.40.50.40.4-0.50.60.50.50.60.4
Progressive ratio test 2 active lever presses2.02.24.31.72.1-1.0-1.5-1.6-1.9-1.4-0.2-1.1-1.5-1.3
Progressive ratio test 2 breakpoint1.92.14.21.62.1-1.1-1.5-1.5-1.9-1.4-0.3-1.1-1.5-1.2
Progressive ratio test 2 inactive lever presses0.80.91.60.60.9-1.2-1.1-1.0-1.3-0.7-0.7-1.0-1.1-0.9
Total sessions with >9 infusions4.95.48.02.82.7-1.6-2.2-2.7-2.8-2.8-0.0-1.1-2.2-2.7
Short access day 1 total inactive lever presses0.20.20.5-0.2-0.70.40.40.5-0.40.60.30.50.50.5
Short access day 10 total inactive lever presses1.11.21.60.81.0-1.2-1.1-1.0-1.2-1.1-1.0-1.1-1.2-1.3
Short access day 1 total infusions0.30.31.61.30.60.1-0.2-0.3-0.7-0.40.90.4-0.0-0.3
Short access day 10 total infusions0.20.20.90.70.40.40.1-0.1-0.4-0.40.90.50.2-0.0
Short access total infusions0.40.41.51.20.90.0-0.4-0.6-0.7-0.70.80.3-0.2-0.5
Short access day 1 locomotion0.40.51.71.31.0-0.2-0.5-0.6-1.0-0.60.2-0.3-0.4-0.4
Short access day 10 total locomotion0.30.41.10.81.0-0.5-0.6-0.7-0.6-0.80.1-0.4-0.6-0.3
Short access total locomotion1.01.03.92.01.6-0.2-0.6-1.0-0.6-1.11.00.1-0.5-0.6
Compulsive drug intake0.30.31.0-0.5-1.00.00.50.70.50.6-0.30.20.40.3
One hour access (0.3 mA shock)0.80.92.10.70.9-1.1-1.0-0.7-1.4-0.7-0.9-1.1-1.0-0.7
One hour access (shock baseline)1.61.93.31.51.8-1.1-1.4-1.4-1.8-1.4-0.3-1.0-1.5-1.3
Number of responses in last shaping day0.20.20.60.80.30.2-0.0-0.1-0.3-0.10.80.3-0.0-0.4
Context. condit. distance diff. score1.92.33.6-0.5-1.61.11.81.61.51.91.21.51.81.7
Locomotion velocity, session 10.10.10.30.6-0.00.30.10.20.10.10.50.40.10.1
Locomotion distance, session 10.20.31.41.20.40.3-0.1-0.3-0.6-0.30.90.50.1-0.3
Locomotion velocity, session 20.50.62.60.9-0.10.90.40.0-0.00.11.61.30.70.0
Locomotion distance, session 20.91.24.02.01.3-0.7-0.9-1.2-1.2-1.30.4-0.2-0.6-1.2
Locomotion velocity, session 30.20.21.00.3-0.00.80.2-0.2-0.40.21.00.80.4-0.1
Locomotion distance, session 30.50.62.00.8-0.31.00.60.2-0.20.51.41.20.90.4
Stereotopy head waving bouts, day 30.10.20.7-0.80.00.1-0.4-0.3-0.5-0.5-0.4-0.2-0.4-0.3
Stereotopy head waving duration, day 30.20.32.2-1.5-0.30.1-0.1-0.0-0.2-0.1-0.5-0.2-0.3-0.1
Locomotion velocity, session 70.30.40.60.60.7-0.8-0.5-0.7-0.4-0.4-0.4-0.6-0.7-0.6
Locomotion distance, session 70.10.10.40.6-0.0-0.50.30.10.40.40.30.20.20.3
Stereotopy head waving bouts, day 70.00.10.1-0.20.10.3-0.2-0.40.1-0.3-0.1-0.1-0.2-0.3
Stereotopy head waving duration, day 71.01.32.00.61.4-0.7-1.3-1.2-0.8-1.4-0.9-1.2-1.4-1.1
Locomotion velocity, session 82.83.44.7-1.3-1.81.71.92.02.01.81.41.82.22.0
Locomotion distance, session 81.62.43.9-0.1-1.51.41.71.41.21.61.92.02.01.4
Degree of sensitization distance0.50.51.6-0.8-0.6-0.80.50.81.30.7-0.7-0.40.20.7
Degree of sensitization stereotypy0.10.10.20.30.40.0-0.3-0.40.3-0.3-0.2-0.3-0.3-0.3
Condit. Reinf. active minus inactive responses0.20.30.5-0.7-0.70.60.30.2-0.30.20.40.70.70.1
Condit. Reinf. active-inactive response ratio0.20.20.8-0.9-0.70.40.30.3-0.10.30.20.50.50.2
Condit. Reinf. active responses0.70.81.8-0.10.5-0.5-1.1-1.2-1.3-1.3-0.6-0.5-0.7-1.2
Condit. Reinf. inactive responses2.12.54.20.41.2-1.2-1.9-1.9-1.7-2.0-1.3-1.3-1.7-1.8
Incentive salience index mean0.30.41.0-0.5-0.70.80.40.2-0.10.20.81.00.80.0
Condit. Reinf. lever presses0.10.10.30.0-0.20.3-0.1-0.2-0.4-0.20.50.50.3-0.2
Time in familiar zone, hab. session 10.10.10.20.30.2-0.1-0.2-0.4-0.3-0.20.30.1-0.1-0.5
Time in novel zone, hab. session 10.40.41.2-0.20.4-0.8-0.6-0.3-0.3-0.4-1.1-1.0-0.6-0.2
Total zone transitions, hab. session 11.01.43.31.81.7-0.7-1.1-1.2-1.2-1.3-0.0-0.7-1.0-1.3
Total locomotion distance, hab. session 10.30.50.9-0.6-0.91.00.70.70.20.80.40.70.80.5
Locomotion velocity, hab. session 10.60.81.5-0.8-1.11.20.90.90.41.00.71.01.10.7
Time in familiar zone, hab. session 21.61.74.1-0.10.7-1.8-1.2-0.9-1.3-0.7-2.0-1.8-1.3-1.1
Time in novel zone, hab. session 20.50.52.20.5-0.01.00.4-0.00.5-0.11.51.10.60.2
Total zone transitions, hab. session 21.51.93.71.91.8-1.3-1.3-1.4-1.5-1.4-0.4-1.0-1.2-1.6
Total locomotion distance, hab. session 20.10.10.40.3-0.00.2-0.0-0.1-0.70.10.10.10.1-0.3
Locomotion velocity, hab. session 20.10.10.20.4-0.10.30.20.1-0.50.20.30.30.3-0.1
Novel to familiar place preference ratio0.10.10.6-0.8-0.4-0.4-0.2-0.20.0-0.2-0.6-0.2-0.20.0
Novelty place preference0.10.10.4-0.6-0.3-0.5-0.3-0.3-0.1-0.3-0.6-0.2-0.2-0.1
Time in novel zone, NPP test0.40.41.2-0.6-0.0-0.9-0.6-0.6-0.4-0.6-1.1-0.7-0.6-0.4
Total zone transitions, NPP test0.40.52.91.71.0-0.8-0.5-0.4-0.5-0.50.1-0.4-0.4-0.5
Total locomotion distance, NPP test0.10.10.30.2-0.50.40.40.5-0.00.50.30.40.50.3
Locomotion velocity, NPP test0.50.71.10.1-0.91.00.90.90.40.90.91.01.10.7
Pavlov. Cond. lever latency0.10.10.6-0.20.1-0.2-0.20.0-0.30.0-0.8-0.6-0.5-0.1
Pavlov. Cond. magazine entry latency0.00.10.20.2-0.3-0.10.10.1-0.20.30.30.30.4-0.0
Pavlov. Cond. change in total contacts0.00.00.10.20.1-0.20.0-0.00.1-0.10.20.10.3-0.0
Pavlov. Cond. index score0.00.10.20.30.1-0.4-0.2-0.2-0.3-0.10.10.10.1-0.3
Pavlov. Cond. latency score0.00.10.10.40.2-0.4-0.2-0.3-0.2-0.20.20.10.1-0.3
Pavlov. Cond. lever contacts0.00.00.10.10.1-0.2-0.2-0.3-0.1-0.20.20.10.1-0.1
Pavlov. Cond. magazine entry number0.30.41.1-0.4-0.40.80.70.81.00.60.20.30.50.8
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.00.20.3-0.6-0.7-0.7-0.7-0.1-0.1-0.4-0.6
Pavlov. Cond. lever-magazine prob. diff.0.00.00.30.10.0-0.5-0.2-0.2-0.2-0.10.00.00.1-0.2
Pavlov. Cond. response bias0.00.10.20.20.0-0.3-0.1-0.3-0.4-0.10.30.20.2-0.3
Bone: apparent density2.13.55.9-0.31.3-2.4-2.0-1.8-1.4-1.9-2.4-2.2-2.1-1.6
Bone surface1.01.72.40.11.2-1.5-1.4-1.4-0.7-1.6-1.5-1.5-1.5-1.1
Bone volume2.95.07.10.72.1-2.7-2.4-2.2-1.9-2.4-2.4-2.5-2.6-2.0
Bone: connectivity density0.20.31.0-0.90.1-0.8-0.4-0.30.1-0.4-1.0-0.7-0.5-0.1
Bone: cortical apparent density1.01.35.00.8-0.21.60.80.50.00.42.21.71.20.5
Bone: cortical area10.315.521.31.93.9-4.1-4.3-4.2-4.0-4.4-3.3-3.9-4.6-4.0
Bone: cortical porosity0.20.21.4-1.2-0.4-0.1-0.2-0.1-0.1-0.2-0.6-0.2-0.3-0.1
Bone: cortical porosity0.30.31.9-1.4-0.4-0.2-0.20.0-0.0-0.2-0.9-0.4-0.40.0
Bone: cortical thickness4.57.510.41.32.7-2.6-3.0-3.1-3.0-3.2-1.9-2.5-3.2-2.9
Bone: cortical thickness1.31.52.31.21.4-1.0-1.3-1.3-1.5-1.5-0.4-0.9-1.4-1.4
Bone: cortical tissue density1.21.65.60.7-0.41.81.10.70.20.72.41.91.40.7
Bone: elastic displacement0.20.20.5-0.5-0.50.30.50.60.40.7-0.00.10.20.7
Bone: elastic work0.40.50.90.70.9-0.2-0.7-0.9-1.0-0.90.1-0.3-0.8-0.7
Bone: endosteal estimation1.83.84.71.52.1-2.2-2.0-2.0-1.5-2.1-1.8-2.1-2.2-1.9
Bone: endosteal perimeter5.711.815.52.93.7-3.5-3.6-3.6-3.3-3.6-2.6-3.4-3.9-3.4
Bone: final force3.76.19.11.92.8-2.4-2.7-2.8-2.3-3.0-1.5-2.1-2.8-2.5
Bone: final moment3.76.18.61.82.7-2.4-2.7-2.8-2.3-2.9-1.6-2.2-2.8-2.5
Bone: marrow area1.83.94.91.52.1-2.2-2.1-2.0-1.5-2.2-1.8-2.1-2.2-1.9
Bone: maximum diameter8.715.921.91.73.8-4.3-4.3-4.1-3.9-4.3-3.7-4.2-4.7-4.0
Bone: maximum force3.15.38.21.62.4-2.2-2.5-2.7-2.3-2.9-1.4-1.9-2.6-2.4
Bone: maximum moment3.05.17.61.42.3-2.2-2.5-2.6-2.3-2.8-1.5-2.0-2.6-2.4
Bone: minimum diameter3.87.09.91.22.6-2.9-2.8-2.7-2.3-3.0-2.6-2.9-3.1-2.5
Bone: periosteal estimation6.012.416.12.13.6-3.7-3.8-3.8-3.3-3.9-2.9-3.5-4.0-3.5
Bone: periosteal perimeter12.620.928.03.34.8-4.7-4.9-4.8-4.5-4.9-3.5-4.5-5.3-4.6
Bone: post-yield work0.10.11.0-1.0-0.4-0.10.10.10.4-0.1-0.4-0.00.20.1
Bone: stiffness2.23.45.51.52.0-1.7-2.0-2.1-1.8-2.3-1.0-1.4-2.1-2.1
Bone: tissue strength0.20.20.6-0.8-0.60.20.40.50.50.6-0.10.10.30.6
Bone: trabecular number1.01.53.5-0.70.7-1.7-1.2-1.0-0.5-1.1-1.9-1.6-1.3-0.8
Bone: trabecular spacing0.10.10.4-0.3-0.60.20.40.50.20.70.10.20.30.3
Bone: trabecular thickness5.66.79.31.12.6-2.8-2.8-2.5-2.5-2.8-2.6-2.9-3.1-2.5
Bone: trabecular tissue density0.50.72.21.50.9-0.2-0.7-0.8-1.1-0.90.4-0.1-0.5-0.8
Breakpoint value in progressive ratio session0.20.30.5-0.7-0.2-0.20.20.50.60.5-0.7-0.40.20.7
Distance traveled before self-admin1.01.12.30.3-0.41.31.01.20.60.81.51.21.11.3
Distance traveled after self-admin0.70.82.90.7-0.21.20.80.70.20.31.71.30.90.5
Delta time in closed arm before/after self-admin0.60.61.00.4-0.70.70.70.70.30.41.01.00.91.0
Delta time in open arm before/after self-admin0.60.51.2-0.40.4-0.7-0.8-0.8-0.3-0.5-1.1-0.9-0.9-0.8
Diff in mean of infusions in LGA sessions2.62.95.6-2.0-1.81.11.71.82.42.1-0.00.71.81.8
Extinction: sum of active levers before priming0.90.91.7-0.9-1.10.41.01.20.91.3-0.10.31.01.1
Active lever presses in extinction session 60.40.30.9-0.9-0.60.60.40.8-0.40.8-0.20.10.40.7
Delta distance traveled before/after self-admin0.20.20.80.90.4-0.1-0.2-0.4-0.4-0.30.30.1-0.1-0.5
Delta ambulatory time before/after self-admin0.10.10.30.40.3-0.4-0.3-0.5-0.4-0.3-0.2-0.2-0.3-0.5
Time in closed arm before self-admin0.00.00.10.10.3-0.10.20.30.00.30.30.00.00.3
Time in closed arm after self-admin1.11.22.40.3-0.70.81.11.21.01.01.31.21.11.6
Time in open arm before self-admin2.42.64.1-1.8-2.01.61.61.61.71.50.61.31.81.8
Time in open arm after self-admin0.30.32.3-1.5-0.70.40.10.10.60.3-0.5-0.00.10.0
Sum of active levers in priming session hrs 5-62.32.23.7-1.9-1.71.61.41.51.51.90.51.01.41.4
Time to tail flick, vehicle, before self-admin2.93.04.70.51.3-1.8-1.9-1.9-2.0-1.5-1.7-1.8-2.2-1.7
Time to tail flick, vehicle, after self-admin0.30.30.8-0.20.50.1-0.6-0.6-0.9-0.9-0.2-0.3-0.6-0.5
Time to tail flick, test, before self-admin0.80.83.31.80.90.2-0.3-0.7-0.8-0.61.40.7-0.1-0.9
Time to tail flick, test, after self-admin2.72.84.10.31.6-1.6-1.8-1.9-1.7-1.9-1.6-1.8-2.0-1.7
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.30.00.50.20.30.2-0.10.10.10.30.2
Delta time to tail flick, test, before/after SA3.43.04.9-0.41.1-1.8-1.8-1.7-1.7-1.9-2.2-2.0-2.2-1.5
Ambulatory time before self-admin0.20.20.80.40.00.30.30.5-0.10.20.90.60.40.4
Ambulatory time after self-admin0.60.62.10.5-0.11.10.70.60.00.51.41.10.90.6
Total heroin consumption0.70.81.8-0.00.9-0.9-1.0-0.7-0.6-0.7-1.3-1.4-1.0-0.7
Area under the delay curve0.80.91.91.01.1-1.4-0.7-0.6-0.7-0.6-1.1-1.3-0.8-0.4
Delay disc. indifference point, 0s delay0.20.30.60.80.8-0.7-0.3-0.3-0.4-0.6-0.2-0.5-0.5-0.0
Delay disc. indifference point, 16s delay0.20.20.80.60.5-0.9-0.10.10.2-0.0-0.8-0.80.00.2
Delay disc. indifference point, 2s delay0.30.30.80.5-0.00.10.60.70.70.70.40.20.70.9
Delay disc. indifference point, 24s delay0.80.83.10.20.4-1.8-0.6-0.4-0.4-0.2-1.5-1.3-0.7-0.3
Delay disc. indifference point, 4s delay0.30.30.8-0.0-0.2-0.10.60.90.70.70.10.00.50.9
Delay disc. indifference point, 8s delay6.16.38.52.42.9-2.6-2.5-2.5-2.5-2.5-2.1-2.7-2.7-2.2
Delay discount exponential model param0.80.91.9-1.0-1.11.40.70.60.70.51.11.30.80.5
Delay discount hyperbolic model param0.50.51.3-0.9-1.01.10.50.30.50.30.91.10.50.2
Fecal boli incidents, locomotor time 12.62.84.00.91.3-1.8-1.7-1.9-1.8-1.8-1.3-1.5-2.0-2.0
Change in fecal boli incidents, locomotor task4.13.96.2-1.8-2.31.82.02.21.92.51.01.62.22.0
Time >=10cm from walls, locomotor time 12.82.84.1-2.0-1.92.01.61.61.51.80.91.51.71.7
Bouts of movement, locomotor time 11.21.32.30.41.2-1.4-1.1-1.0-0.6-1.1-1.3-1.5-1.4-1.0
Total resting periods, locomotor time 10.91.01.50.51.1-1.2-1.0-1.0-0.6-1.0-1.0-1.2-1.2-0.9
Rest time, locomotor task time 10.50.61.11.11.0-0.5-0.6-1.0-0.4-1.00.4-0.1-0.7-0.9
Distance moved, locomotor task time 10.30.41.1-1.0-0.60.40.50.9-0.00.8-0.4-0.10.50.5
Vertical activity count, locomotor time 11.71.82.8-1.4-1.51.61.41.70.81.50.71.11.51.3
Time >=10cm from walls, locomotor time 20.20.20.9-0.9-0.50.20.10.30.20.2-0.6-0.10.10.5
Bouts of movement, locomotor time 22.32.55.3-0.8-1.11.21.71.82.31.51.01.21.72.1
Total resting periods, locomotor time 21.41.53.5-0.5-0.61.01.41.51.91.20.80.81.41.8
Rest time, locomotor task time 20.20.20.70.80.7-0.4-0.2-0.3-0.4-0.40.1-0.2-0.4-0.4
Distance moved, locomotor task time 20.30.30.7-0.30.3-0.7-0.6-0.4-0.5-0.6-0.9-0.8-0.6-0.5
Vertical activity count, locomotor time 20.20.30.6-0.30.2-0.6-0.6-0.5-0.5-0.8-0.6-0.5-0.5-0.4
Weight adjusted by age8.29.112.42.73.2-2.7-3.1-3.3-3.4-3.2-1.8-2.7-3.2-3.5
Seeking ratio, delayed vs. immediate footshock0.91.01.6-0.2-1.01.01.00.71.01.01.21.31.30.8
Locomotion in novel chamber0.60.72.30.3-0.40.90.70.50.30.81.51.31.00.5
Locomotion in novel chamber post-restriction1.11.33.90.3-0.71.80.90.40.50.62.01.81.20.5
Progressive ratio0.91.12.2-1.5-1.21.21.01.00.81.00.40.80.91.1
Food seeking constrained by brief footshock1.01.23.1-1.2-1.20.31.11.70.81.5-0.20.30.91.4
Seeking ratio, punishment vs. effort0.10.10.70.80.3-0.7-0.00.2-0.20.1-0.0-0.2-0.1-0.1
Run reversals in cocaine runway, females1.01.01.71.11.0-0.7-1.1-1.3-1.0-1.1-0.1-0.5-1.0-1.3
Run reversals in cocaine runway, males2.72.64.0-1.4-1.71.31.92.01.82.00.91.21.61.7
Latency to leave start box in cocaine runway0.80.81.7-0.4-0.91.11.11.30.91.20.10.40.90.8
Latency to leave start box in cocaine runway, F1.11.32.3-0.8-1.21.41.31.51.11.40.30.71.11.0
Latency to leave start box in cocaine runway, M0.30.31.41.20.8-0.3-0.4-0.3-0.3-0.3-0.2-0.5-0.4-0.4
Cd content in liver2.32.63.7-1.6-1.91.71.61.61.71.61.01.51.71.6
Co content in liver0.10.20.70.80.20.5-0.1-0.30.3-0.30.60.4-0.1-0.3
Cu content in liver0.20.20.50.70.7-0.1-0.4-0.5-0.5-0.70.2-0.1-0.3-0.5
Fe content in liver0.10.10.4-0.6-0.10.2-0.3-0.3-0.2-0.3-0.3-0.1-0.1-0.3
K content in liver0.20.20.90.0-0.20.10.50.60.90.40.30.30.30.5
Mg content in liver0.10.10.2-0.1-0.0-0.30.20.40.50.2-0.3-0.3-0.20.3
Mn content in liver1.21.42.2-0.3-0.90.91.41.51.31.11.01.11.31.5
Na content in liver0.20.20.9-0.6-0.2-0.10.40.60.90.3-0.3-0.20.30.6
Rb content in liver1.31.72.7-1.1-1.41.01.41.61.61.50.40.81.21.6
Se content in liver0.10.10.6-0.70.00.2-0.00.10.3-0.3-0.4-0.2-0.10.0
Sr content in liver2.72.53.8-0.1-1.21.71.81.51.61.32.01.91.81.5
Zn content in liver2.02.23.1-0.3-1.21.41.81.71.61.41.71.71.61.6