Hub : Genes

P4ha3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000017118 0.12 0.08 3.5e-05 0.07 0.07 0.06 0.07 1.2e-04 1.0e-04 2.8e-04 9.7e-05
2 BLA mRNA stability ENSRNOG00000017118 0.28 0.14 8.6e-13 0.19 0.22 0.19 0.23 2.2e-10 3.5e-12 1.4e-10 2.1e-12
3 Brain gene expression ENSRNOG00000017118 0.25 0.14 3.0e-14 0.14 0.16 0.16 0.15 4.1e-13 3.4e-14 3.2e-14 4.4e-14
4 Brain mRNA stability ENSRNOG00000017118 0.28 0.14 0.0e+00 0.29 0.29 0.29 0.29 2.3e-27 9.7e-27 5.8e-27 1.9e-27
5 IL mRNA stability ENSRNOG00000017118 0.33 0.17 3.4e-05 0.07 0.06 0.01 0.05 7.6e-03 1.3e-02 1.5e-01 2.0e-02
6 LHb mRNA stability ENSRNOG00000017118 0.25 0.15 1.7e-04 0.06 0.13 0.1 0.09 1.3e-02 5.0e-04 1.9e-03 3.2e-03
7 NAcc gene expression ENSRNOG00000017118 0.16 0.1 6.2e-07 0.08 0.06 0.08 0.07 2.0e-06 2.3e-05 1.3e-06 3.3e-06
8 NAcc mRNA stability ENSRNOG00000017118 0.05 0.04 1.3e-03 0.04 0.03 0.04 0.03 5.7e-04 1.7e-03 6.1e-04 1.7e-03
9 OFC mRNA stability ENSRNOG00000017118 0.32 0.16 6.3e-06 0.2 0.18 0.11 0.15 2.0e-05 4.5e-05 1.4e-03 2.2e-04
10 PL gene expression ENSRNOG00000017118 0.23 0.13 5.0e-12 0.17 0.1 0.15 0.01 2.7e-13 4.6e-08 1.2e-11 5.0e-02
11 PL mRNA stability ENSRNOG00000017118 0.48 0.19 0.0e+00 0.41 0.41 0.42 0.41 7.7e-33 2.4e-33 5.4e-34 2.3e-33

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.10.30.4-0.5-0.50.6-0.6-0.5-0.60.6-0.6-0.5-0.1-0.5
BMI without tail1.32.86.9-1.3-1.22.5-1.3-1.3-2.12.6-1.3-1.31.3-1.1
Body weight1.04.39.7-1.8-1.82.9-1.8-1.8-2.63.1-1.8-1.81.1-1.5
Epididymis fat weight1.74.15.5-2.2-2.21.6-2.1-2.2-2.41.9-2.2-2.2-0.5-2.1
Glucose0.10.10.20.50.5-0.30.40.30.4-0.40.40.4-0.00.4
Heart weight0.91.21.91.21.20.71.21.20.80.41.31.21.31.4
Left kidney weight0.82.28.7-0.7-0.72.9-0.4-0.6-1.52.7-0.6-0.61.8-0.4
Right kidney weight0.51.55.3-0.7-0.72.3-0.4-0.7-1.32.2-0.6-0.61.4-0.4
Tail length2.47.122.0-1.5-1.54.7-1.5-1.5-3.14.7-1.5-1.53.2-1.1
Length with tail1.65.915.3-1.8-1.83.7-1.9-1.8-3.03.9-1.8-1.82.1-1.4
Length without tail0.10.20.5-0.4-0.4-0.4-0.5-0.4-0.2-0.2-0.5-0.4-0.7-0.4
Liver weight, left1.82.94.1-1.9-1.91.1-2.0-1.9-2.01.5-1.9-1.8-0.4-1.8
Liver weight, right4.16.89.3-2.9-2.81.5-2.9-2.9-3.12.2-2.9-2.9-0.6-2.8
Parametrial fat weight1.73.35.1-2.0-2.00.7-2.3-2.0-2.01.2-2.2-2.0-0.8-2.0
Retroperitoneal fat weight7.023.131.7-5.5-5.42.4-5.6-5.3-5.53.5-5.3-5.3-1.5-5.3
Intraocular pressure0.60.81.41.01.0-0.61.20.91.1-0.81.10.90.10.9
Extensor digitorum longus weight0.51.93.0-1.4-1.41.3-1.4-1.5-1.71.6-1.4-1.5-0.1-1.4
Soleus weight1.44.16.7-2.0-2.02.1-2.0-2.1-2.62.5-2.0-2.00.3-1.9
Tibialis anterior weight0.20.51.6-0.5-0.51.2-0.5-0.5-0.91.3-0.5-0.50.6-0.4
Tibia length2.16.08.32.92.8-0.12.92.82.4-0.82.82.71.92.9
Number of licking bursts4.45.27.5-2.7-2.6-0.6-2.5-2.6-1.9-0.0-2.5-2.6-2.4-2.7
Food consumed during 24 hour testing period3.54.25.92.32.30.62.32.31.7-0.02.42.32.02.4
Times rat made contact with spout1.01.21.6-1.2-1.20.7-1.1-1.2-1.30.9-1.1-1.2-0.3-1.2
Mean time between licks in bursts2.43.312.90.40.43.60.30.3-1.13.30.30.33.20.7
Mean num. licks in bursts3.23.95.62.22.20.82.22.21.50.32.12.22.22.4
Std. dev. time between licks in bursts1.51.86.2-0.6-0.62.5-0.6-0.7-1.52.5-0.5-0.71.6-0.4
Water consumed over 24 hours0.30.31.0-0.4-0.4-0.9-0.4-0.40.0-0.7-0.3-0.4-1.0-0.5
Indifference point 0 sec2.64.16.42.22.21.62.12.21.30.92.22.22.52.3
Indifference point AUC0.70.81.6-0.8-0.81.1-0.6-0.8-1.11.3-0.8-0.90.3-0.8
Indifference point function ln k2.43.44.62.12.1-0.72.12.12.1-1.22.12.10.82.1
Indifference point function log k2.43.44.62.12.1-0.72.12.12.1-1.22.12.10.82.1
Delay discounting total patch changes 0 sec1.93.25.21.91.91.51.81.91.00.91.91.92.32.0
Delay discounting total patch changes 12 sec0.60.83.4-0.0-0.01.90.20.0-0.71.7-0.0-0.01.40.1
Delay discounting total patch changes 18 sec1.01.33.11.01.01.60.91.00.21.30.90.91.71.1
Delay discounting total patch changes 24 sec0.50.72.60.10.11.60.00.0-0.71.6-0.00.11.40.2
Delay discounting total patch changes 6 sec0.40.61.20.80.80.51.10.80.50.20.80.80.90.8
Delay discounting time to switch 0 sec1.82.87.2-1.6-1.6-1.9-1.6-1.5-0.6-1.3-1.7-1.5-2.7-1.8
Delay discounting water rate 0 sec2.13.35.62.02.01.21.91.91.20.61.91.92.42.1
Delay discounting water rate 12 sec2.03.04.32.02.00.42.02.01.5-0.01.81.91.82.1
Delay discounting water rate 18 sec0.70.93.40.80.80.90.80.80.20.70.90.81.80.9
Delay discounting water rate 24 sec2.12.84.71.91.9-0.62.21.81.8-1.11.91.81.01.8
Delay discounting water rate 6 sec1.31.82.61.61.5-0.01.61.51.3-0.41.51.51.41.6
Locomotor activity0.40.71.50.90.90.51.20.90.70.11.00.80.70.9
Locomotor testing distance0.91.53.51.11.11.61.41.10.41.11.11.11.91.2
Locomotor testing rearing0.50.83.3-0.3-0.31.8-0.0-0.3-0.91.6-0.3-0.31.1-0.1
Light reinforcement 11.62.95.7-1.8-1.8-1.0-1.9-1.8-1.1-0.7-1.9-1.8-2.4-2.0
Light reinforcement 20.20.30.90.10.1-0.90.10.10.5-0.90.20.1-0.9-0.0
Reaction time number correct1.11.63.01.21.2-1.41.41.21.6-1.71.31.1-0.21.1
Reaction time mean minus median0.30.41.20.40.31.10.30.4-0.11.00.30.41.10.5
Reaction time mean minus median AUC0.70.91.61.11.00.61.01.00.60.40.91.11.21.1
Reaction time num false alarms2.02.84.0-1.9-1.9-0.2-1.9-1.9-1.50.2-1.9-1.9-1.6-2.0
Reaction time num false alarms AUC0.91.21.8-1.2-1.2-0.3-1.3-1.2-0.9-0.1-1.3-1.2-1.3-1.3
Reaction time trials correct on left1.11.63.01.21.2-1.41.41.21.6-1.71.31.1-0.21.1
Reaction time trials on left1.11.63.11.21.2-1.51.41.11.6-1.71.31.1-0.21.1
Reaction time mean1.01.32.4-1.3-1.30.1-1.5-1.3-1.10.4-1.3-1.3-0.8-1.3
Reaction time mean AUC0.91.22.4-1.2-1.2-0.3-1.5-1.2-1.00.0-1.2-1.2-1.1-1.3
Median of all reaction times1.21.73.0-1.4-1.4-0.4-1.7-1.4-1.1-0.0-1.4-1.4-1.3-1.5
Reaction time omissions0.40.60.9-0.9-0.90.2-1.0-0.9-0.80.4-0.8-0.9-0.7-0.9
Reaction time false alarm rate1.82.63.7-1.8-1.80.3-1.9-1.8-1.60.7-1.9-1.8-1.2-1.9
Reaction time premature initiation rate1.41.96.4-0.6-0.52.5-0.6-0.5-1.42.5-0.6-0.41.9-0.3
Reaction time premature initiations0.50.72.80.30.31.40.30.3-0.31.20.30.41.70.5
Std. dev. reaction times0.71.02.4-0.8-0.81.5-0.8-0.8-1.21.6-0.8-0.80.8-0.7
Reaction time trials completed1.11.63.11.21.2-1.51.41.11.6-1.71.31.1-0.21.1
Reaction time trials AUC0.81.22.31.01.0-1.21.21.01.4-1.51.10.9-0.10.9
Social response proportion0.70.81.4-1.0-1.00.3-0.9-1.0-1.00.6-1.2-1.0-0.1-1.0
Social responses1.51.92.9-1.5-1.51.0-1.5-1.5-1.71.4-1.6-1.40.1-1.4
Social time1.21.64.3-1.0-1.0-1.9-1.1-1.0-0.2-1.4-1.2-1.0-2.1-1.2
Conditioned locomotion0.10.10.40.20.2-0.70.20.20.4-0.70.20.2-0.40.2
Cocaine response after cond. corrected2.32.53.5-1.8-1.80.1-1.8-1.8-1.60.5-1.9-1.8-1.3-1.9
Cocaine response after cond. not corrected0.50.60.8-0.9-0.8-0.0-0.9-0.9-0.70.2-0.9-0.9-0.7-0.9
Cocaine response before conditioning2.63.14.42.12.1-0.22.02.01.8-0.72.12.01.22.1
Saline control response0.91.24.00.80.71.70.70.7-0.11.40.70.72.00.9
Condit. Reinf. active minus inactive responses3.24.012.71.61.62.81.61.50.22.31.61.53.61.9
Condit. Reinf. active-inactive response ratio1.01.02.51.01.01.01.01.00.40.71.01.01.61.1
Condit. Reinf. active responses4.05.518.61.61.63.61.71.6-0.13.01.61.64.32.0
Condit. Reinf. inactive responses2.22.79.60.90.92.81.00.9-0.42.40.90.93.11.2
Condit. Reinf. lever presses9.012.431.53.43.33.73.43.31.32.73.43.35.63.8
Condit. Reinf. lever reinforcers received4.66.520.72.01.93.72.11.90.22.91.91.94.62.3
Pavlov. Cond. lever latency9.613.230.7-3.6-3.6-3.5-3.7-3.6-1.6-2.4-3.6-3.6-5.5-4.0
Pavlov. Cond. magazine entry latency3.13.65.42.12.10.92.12.11.40.42.02.12.32.2
Pavlov. Cond. change in total contacts8.111.323.23.53.52.73.63.51.81.73.53.54.83.8
Pavlov. Cond. index score7.910.422.63.33.32.83.33.21.61.83.23.24.83.6
Pavlov. Cond. latency score7.29.219.43.23.12.53.23.11.61.63.13.14.43.4
Pavlov. Cond. lever contacts10.013.932.23.73.73.53.83.71.72.43.73.75.74.1
Pavlov. Cond. magazine entry number5.46.610.0-2.9-2.8-1.3-2.9-2.8-1.9-0.5-2.8-2.8-3.2-3.0
Pavlov. Cond. intertrial magazine entries1.11.42.6-1.1-1.11.4-1.1-1.1-1.51.6-1.1-1.10.5-1.0
Pavlov. Cond. lever-magazine prob. diff.7.29.321.43.13.12.83.13.01.41.93.03.04.63.4
Pavlov. Cond. response bias10.614.631.93.93.93.44.03.91.92.23.83.95.64.3
Conditioned reinforcement - actives3.23.24.82.02.00.32.22.01.6-0.22.02.21.52.1
Conditioned reinforcement - inactives0.20.30.5-0.5-0.50.2-0.7-0.5-0.60.5-0.7-0.3-0.2-0.5
Conditioned locomotion3.74.47.22.52.4-0.32.42.42.1-0.82.72.11.32.5
Intermittent access intake day 1-15 change0.60.61.50.70.70.21.20.70.60.11.00.80.90.8
Intermittent access intake escalation0.80.82.00.80.80.21.40.80.70.01.20.90.90.9
Intermittent access intake escalation 20.20.20.5-0.2-0.20.60.4-0.2-0.30.60.1-0.20.7-0.1
Intermitt. access day 1 inactive lever presses0.40.50.9-0.8-0.80.1-0.9-0.8-0.80.4-0.9-0.5-0.3-0.8
Intermitt. access day 15 inactive lever presses0.40.40.80.80.8-0.30.50.80.7-0.30.60.90.10.7
Intermitt. access escalation Index0.20.20.30.40.40.30.60.40.30.10.50.50.50.5
Intermittent access day 1 total infusions0.80.91.91.11.10.90.71.10.40.60.91.01.41.1
Intermittent access day 15 total infusions1.61.82.51.51.40.51.51.41.00.21.61.51.51.6
Intermittent access terminal intake (last 3 days)1.11.22.11.11.10.81.21.10.60.51.31.11.41.3
Intermittent access total infusions0.80.91.91.01.00.70.81.00.50.50.91.01.41.1
Intermittent access day 1 locomotion0.30.30.60.80.7-0.20.60.70.6-0.30.70.50.10.7
Intermittent access day 15 total locomotion1.41.52.81.41.40.21.71.41.1-0.11.61.11.01.4
Intermittent access total locomotion0.60.71.11.01.00.40.91.00.60.21.00.70.91.0
Intermittent access standard deviation0.10.10.3-0.2-0.20.60.1-0.2-0.30.5-0.1-0.10.3-0.1
Cocaine induced anxiety1.31.53.8-1.3-1.3-0.9-1.1-1.3-0.7-0.6-1.3-1.3-2.0-1.4
Post-drug Anxiety1.11.21.8-1.3-1.3-0.1-1.1-1.3-1.00.1-1.3-1.3-0.9-1.3
Baseline Anxiety0.50.62.60.50.50.90.50.50.00.70.60.51.60.7
Lifetime Intake1.11.22.61.21.20.70.91.20.60.51.01.21.61.3
Incentive Sensitization - Responses0.90.92.90.60.61.71.00.6-0.11.20.60.51.60.7
Incentive Sensitization - Breakpoint0.90.92.30.70.71.51.20.70.11.00.80.61.50.8
Progressive ratio test 1 active lever presses0.00.00.1-0.1-0.1-0.3-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Progressive ratio test 1 breakpoint0.00.00.1-0.2-0.2-0.1-0.3-0.2-0.30.1-0.3-0.2-0.0-0.2
Progressive ratio test 1 inactive lever presses0.30.30.70.60.60.6-0.00.60.10.60.10.60.80.6
Progressive ratio test 2 active lever presses0.40.51.30.50.51.20.70.50.00.90.40.41.10.6
Progressive ratio test 2 breakpoint0.40.51.50.50.51.20.70.5-0.01.00.40.41.10.6
Progressive ratio test 2 inactive lever presses0.91.11.71.31.30.41.11.30.90.11.01.20.91.3
Total sessions with >9 infusions2.73.04.52.02.00.41.72.01.40.11.82.02.02.1
Short access day 1 total inactive lever presses0.10.10.30.10.1-0.5-0.30.10.1-0.3-0.40.2-0.00.1
Short access day 10 total inactive lever presses0.10.10.2-0.1-0.1-0.40.1-0.10.1-0.4-0.2-0.0-0.4-0.2
Short access day 1 total infusions1.51.64.51.31.31.21.01.30.50.81.11.32.11.4
Short access day 10 total infusions0.70.82.70.70.71.30.60.7-0.01.10.50.61.60.8
Short access total infusions0.70.72.40.90.90.90.40.90.20.70.50.91.61.0
Short access day 1 locomotion2.93.04.42.12.1-0.21.92.11.7-0.62.01.91.22.1
Short access day 10 total locomotion0.20.20.70.10.10.80.60.1-0.10.60.4-0.00.60.2
Short access total locomotion0.10.10.30.40.40.20.40.40.30.20.60.20.30.5
Compulsive drug intake0.40.40.70.50.5-0.70.60.50.8-0.90.40.7-0.60.4
One hour access (0.3 mA shock)1.31.53.41.21.21.01.41.20.60.71.21.31.81.3
One hour access (shock baseline)0.91.03.20.80.81.11.10.80.20.91.00.71.81.0
Number of responses in last shaping day0.20.21.0-0.1-0.11.0-0.1-0.1-0.50.9-0.2-0.30.6-0.1
Context. condit. distance diff. score2.53.04.22.02.00.22.02.01.6-0.32.02.01.52.1
Locomotion velocity, session 10.40.51.50.50.5-1.10.40.40.8-1.20.40.4-0.60.4
Locomotion distance, session 11.11.41.91.41.3-0.21.31.31.2-0.51.41.30.81.4
Locomotion velocity, session 20.00.00.10.10.10.20.10.1-0.00.20.10.10.40.1
Locomotion distance, session 20.40.60.90.90.90.10.90.90.7-0.10.90.90.60.9
Locomotion velocity, session 31.21.41.91.41.4-0.51.41.21.3-0.81.41.20.51.4
Locomotion distance, session 32.12.33.21.81.8-0.51.81.71.7-0.91.81.70.71.8
Stereotopy head waving bouts, day 30.70.81.1-1.0-1.00.4-1.0-1.0-1.00.6-1.0-1.0-0.3-1.0
Stereotopy head waving duration, day 30.10.20.20.50.5-0.20.40.50.5-0.30.40.50.10.5
Locomotion velocity, session 70.10.10.5-0.1-0.1-0.7-0.1-0.00.2-0.6-0.1-0.0-0.6-0.1
Locomotion distance, session 70.10.20.2-0.5-0.5-0.1-0.4-0.4-0.30.0-0.4-0.4-0.4-0.5
Stereotopy head waving bouts, day 72.42.83.92.01.90.41.91.91.5-0.11.91.91.52.0
Stereotopy head waving duration, day 72.42.94.12.02.00.81.91.81.30.31.91.81.92.0
Locomotion velocity, session 80.70.81.11.11.00.31.01.00.7-0.01.01.00.91.1
Locomotion distance, session 81.92.94.01.91.90.62.01.91.40.11.91.91.82.0
Degree of sensitization distance3.03.04.4-2.0-1.91.3-1.9-1.8-2.11.7-1.9-1.8-0.2-1.8
Degree of sensitization stereotypy5.15.57.82.82.70.72.72.62.0-0.02.72.62.32.8
Condit. Reinf. active minus inactive responses0.30.31.0-0.3-0.31.0-0.3-0.3-0.61.0-0.3-0.30.6-0.2
Condit. Reinf. active-inactive response ratio0.40.51.7-0.2-0.21.3-0.1-0.2-0.71.3-0.2-0.21.0-0.1
Condit. Reinf. active responses0.10.10.3-0.3-0.30.5-0.4-0.3-0.50.5-0.3-0.30.2-0.3
Condit. Reinf. inactive responses0.00.00.10.00.0-0.3-0.0-0.00.1-0.30.0-0.0-0.3-0.0
Incentive salience index mean0.20.20.8-0.1-0.10.9-0.1-0.2-0.50.9-0.1-0.20.7-0.0
Condit. Reinf. lever presses0.00.10.20.10.10.40.10.0-0.10.40.10.00.30.1
Time in familiar zone, hab. session 10.20.20.4-0.4-0.40.5-0.4-0.4-0.60.6-0.4-0.40.2-0.4
Time in novel zone, hab. session 10.20.20.3-0.5-0.4-0.3-0.5-0.5-0.3-0.2-0.4-0.5-0.6-0.5
Total zone transitions, hab. session 10.40.61.00.70.7-0.90.80.81.0-1.00.70.8-0.30.7
Total locomotion distance, hab. session 11.82.63.6-1.8-1.80.9-1.8-1.8-1.91.3-1.8-1.8-0.5-1.8
Locomotion velocity, hab. session 11.11.52.1-1.4-1.40.7-1.3-1.3-1.51.1-1.4-1.3-0.4-1.3
Time in familiar zone, hab. session 20.80.82.40.70.71.20.80.70.10.90.70.71.60.9
Time in novel zone, hab. session 20.20.20.7-0.1-0.1-0.8-0.2-0.10.3-0.8-0.1-0.1-0.9-0.2
Total zone transitions, hab. session 21.72.33.11.81.7-0.11.71.71.5-0.51.71.71.01.8
Total locomotion distance, hab. session 21.01.32.5-1.0-1.01.4-1.1-1.0-1.51.6-1.1-1.00.4-1.0
Locomotion velocity, hab. session 21.31.83.1-1.3-1.31.5-1.4-1.3-1.71.7-1.3-1.30.3-1.2
Novel to familiar place preference ratio0.10.10.10.30.30.00.20.30.2-0.00.30.30.20.3
Novelty place preference0.10.10.10.30.30.00.30.30.3-0.10.30.30.20.3
Time in novel zone, NPP test0.20.20.30.50.50.10.50.50.4-0.00.50.50.30.5
Total zone transitions, NPP test0.50.71.01.01.0-0.40.90.91.0-0.61.00.90.20.9
Total locomotion distance, NPP test1.21.72.5-1.4-1.40.9-1.4-1.4-1.61.2-1.4-1.4-0.3-1.4
Locomotion velocity, NPP test1.52.22.9-1.7-1.60.7-1.7-1.6-1.71.1-1.7-1.6-0.6-1.7
Pavlov. Cond. lever latency0.70.91.9-1.0-1.0-1.0-0.9-0.8-0.3-0.7-0.9-0.8-1.4-1.0
Pavlov. Cond. magazine entry latency1.51.95.21.31.21.61.31.20.41.21.31.22.31.5
Pavlov. Cond. change in total contacts0.70.82.30.80.81.10.80.80.20.90.80.81.50.9
Pavlov. Cond. index score1.51.95.01.31.31.71.21.10.31.31.21.12.21.4
Pavlov. Cond. latency score1.51.94.71.31.31.61.31.20.41.21.21.22.21.4
Pavlov. Cond. lever contacts0.60.72.00.60.61.30.60.5-0.01.10.60.51.40.7
Pavlov. Cond. magazine entry number1.92.45.6-1.6-1.5-1.5-1.6-1.5-0.7-1.0-1.5-1.5-2.4-1.7
Pavlov. Cond. intertrial magazine entries0.50.61.5-0.7-0.7-1.0-0.7-0.7-0.2-0.7-0.7-0.7-1.2-0.8
Pavlov. Cond. lever-magazine prob. diff.1.21.54.01.11.11.51.11.10.31.11.11.12.01.3
Pavlov. Cond. response bias0.60.72.10.70.71.20.60.60.01.00.60.61.50.8
Bone: apparent density0.10.20.70.30.3-0.80.40.30.6-0.80.40.3-0.50.3
Bone surface0.40.81.60.90.90.71.00.90.40.50.90.91.21.0
Bone volume0.30.50.80.70.70.50.80.70.40.30.80.70.90.8
Bone: connectivity density0.40.71.00.80.8-0.90.90.81.0-1.00.90.8-0.20.7
Bone: cortical apparent density2.12.84.0-1.9-1.9-0.1-1.8-2.0-1.60.4-1.9-1.9-1.4-2.0
Bone: cortical area0.20.31.10.00.01.10.20.0-0.41.0-0.00.00.90.1
Bone: cortical porosity1.61.72.41.51.5-0.31.51.51.4-0.71.41.50.71.5
Bone: cortical porosity1.41.52.11.41.4-0.41.41.51.4-0.71.41.40.61.4
Bone: cortical thickness0.10.10.3-0.3-0.3-0.4-0.1-0.2-0.0-0.3-0.3-0.3-0.5-0.3
Bone: cortical thickness0.30.30.60.60.6-0.20.80.60.6-0.30.60.60.20.6
Bone: cortical tissue density2.02.63.8-1.9-1.8-0.2-1.7-2.0-1.50.3-1.9-1.9-1.4-1.9
Bone: elastic displacement1.01.13.8-0.7-0.6-1.7-0.6-0.70.1-1.5-0.8-0.6-1.9-0.9
Bone: elastic work0.91.13.9-0.4-0.4-2.0-0.3-0.40.5-1.8-0.6-0.4-2.0-0.6
Bone: endosteal estimation0.61.45.50.10.12.30.00.1-0.92.20.10.12.10.3
Bone: endosteal perimeter0.81.55.50.40.42.30.40.5-0.62.10.50.42.30.7
Bone: final force0.00.00.1-0.2-0.20.1-0.1-0.2-0.20.1-0.3-0.2-0.1-0.2
Bone: final moment0.00.00.1-0.1-0.10.30.1-0.0-0.10.3-0.1-0.00.2-0.0
Bone: marrow area0.61.35.0-0.1-0.12.2-0.1-0.1-1.02.1-0.0-0.01.90.1
Bone: maximum diameter0.81.44.60.70.72.00.80.7-0.21.70.60.72.10.9
Bone: maximum force0.00.00.10.00.00.30.10.0-0.10.2-0.10.00.20.0
Bone: maximum moment0.00.10.20.20.20.40.30.2-0.00.40.10.20.50.2
Bone: minimum diameter1.01.95.5-1.0-1.02.2-1.0-1.0-1.72.3-0.9-1.01.2-0.8
Bone: periosteal estimation0.61.14.40.10.12.10.20.2-0.71.90.10.21.90.3
Bone: periosteal perimeter0.61.03.30.40.41.80.40.5-0.41.60.40.41.80.6
Bone: post-yield work0.10.10.20.40.40.30.30.40.20.20.50.40.50.4
Bone: stiffness0.50.91.2-1.0-1.00.5-1.0-1.0-1.10.8-1.1-1.0-0.2-1.0
Bone: tissue strength1.21.23.10.90.8-1.60.80.91.4-1.80.80.8-0.80.7
Bone: trabecular number0.40.62.5-0.2-0.2-1.6-0.1-0.20.5-1.4-0.0-0.2-1.4-0.3
Bone: trabecular spacing0.60.71.11.01.00.50.91.00.60.30.81.01.11.0
Bone: trabecular thickness0.30.30.4-0.6-0.6-0.0-0.6-0.6-0.50.1-0.7-0.6-0.5-0.6
Bone: trabecular tissue density3.04.25.7-2.3-2.31.0-2.2-2.4-2.31.5-2.4-2.3-0.8-2.3
Breakpoint value in progressive ratio session0.30.30.90.20.2-0.80.20.20.6-0.90.30.2-0.90.1
Distance traveled before self-admin1.21.22.2-1.3-1.3-0.4-0.9-1.5-0.8-0.2-1.1-1.3-1.2-1.4
Distance traveled after self-admin0.80.92.90.70.7-1.70.40.51.1-1.60.90.7-0.80.5
Delta time in closed arm before/after self-admin5.35.27.3-2.6-2.51.4-2.3-2.7-2.61.7-2.7-2.5-0.6-2.4
Delta time in open arm before/after self-admin2.52.44.51.71.61.21.41.70.80.81.61.62.11.8
Diff in mean of infusions in LGA sessions2.83.14.5-2.0-2.0-0.9-1.9-1.9-1.3-0.4-2.1-2.0-1.9-2.1
Extinction: sum of active levers before priming0.10.10.4-0.3-0.30.0-0.6-0.4-0.30.1-0.2-0.3-0.3-0.3
Active lever presses in extinction session 64.94.78.22.52.4-0.72.52.32.4-1.32.92.40.72.4
Delta distance traveled before/after self-admin2.32.43.71.91.9-0.51.31.91.5-0.61.81.91.11.8
Delta ambulatory time before/after self-admin2.93.24.92.12.1-0.81.42.21.9-1.02.12.10.92.1
Time in closed arm before self-admin5.15.87.82.82.7-1.22.72.82.7-1.62.72.70.82.7
Time in closed arm after self-admin0.50.52.00.00.0-1.40.3-0.10.6-1.3-0.20.0-1.2-0.1
Time in open arm before self-admin4.54.87.2-2.6-2.5-0.4-2.3-2.5-1.80.0-2.3-2.5-2.2-2.7
Time in open arm after self-admin0.80.92.4-0.7-0.71.5-0.7-0.5-1.21.5-0.5-0.70.7-0.6
Sum of active levers in priming session hrs 5-60.20.20.60.10.1-0.50.40.10.4-0.70.40.1-0.8-0.0
Time to tail flick, vehicle, before self-admin0.10.10.30.20.2-0.40.30.00.3-0.50.40.2-0.50.1
Time to tail flick, vehicle, after self-admin2.93.14.72.12.10.11.72.11.5-0.11.82.11.72.2
Time to tail flick, test, before self-admin0.20.20.8-0.1-0.10.9-0.40.1-0.40.90.2-0.10.70.1
Time to tail flick, test, after self-admin0.90.92.3-0.7-0.61.5-0.8-0.6-1.21.5-0.7-0.60.9-0.5
Delta time to tail flick, vehicle, before/after SA1.81.72.91.61.60.31.01.61.00.21.21.61.71.7
Delta time to tail flick, test, before/after SA0.30.30.8-0.6-0.6-0.1-0.5-0.6-0.50.1-0.9-0.6-0.3-0.6
Ambulatory time before self-admin0.90.91.9-1.0-1.0-0.7-0.6-1.2-0.5-0.5-0.9-1.0-1.4-1.1
Ambulatory time after self-admin1.61.83.71.21.2-1.90.91.11.7-1.91.31.2-0.71.0
Total heroin consumption0.50.61.00.90.9-0.10.91.00.9-0.41.00.90.30.9
Area under the delay curve0.20.20.2-0.5-0.50.5-0.4-0.5-0.40.3-0.4-0.5-0.3-0.5
Delay disc. indifference point, 0s delay0.30.31.00.50.50.90.50.50.10.60.50.41.00.5
Delay disc. indifference point, 16s delay0.00.00.20.00.0-0.20.10.00.2-0.30.00.0-0.5-0.1
Delay disc. indifference point, 2s delay0.40.52.3-0.1-0.11.5-0.2-0.1-0.61.3-0.1-0.10.9-0.0
Delay disc. indifference point, 24s delay0.50.51.8-0.7-0.7-0.6-0.5-0.7-0.2-0.6-0.7-0.7-1.3-0.8
Delay disc. indifference point, 4s delay0.60.72.8-0.4-0.31.7-0.2-0.3-0.91.5-0.3-0.31.0-0.2
Delay disc. indifference point, 8s delay0.00.00.2-0.1-0.10.5-0.1-0.1-0.10.2-0.0-0.1-0.0-0.1
Delay discount exponential model param0.20.20.30.50.5-0.50.50.50.5-0.30.40.50.30.5
Delay discount hyperbolic model param0.30.30.60.50.5-0.80.50.50.6-0.60.40.50.10.5
Fecal boli incidents, locomotor time 11.51.62.21.41.4-0.31.51.41.3-0.61.51.40.71.5
Change in fecal boli incidents, locomotor task1.01.01.3-1.1-1.1-0.6-1.2-1.1-0.8-0.1-1.1-1.1-1.0-1.2
Time >=10cm from walls, locomotor time 12.12.13.11.71.70.21.81.71.3-0.21.71.71.11.7
Bouts of movement, locomotor time 10.20.30.40.60.6-0.00.60.60.5-0.10.70.60.30.6
Total resting periods, locomotor time 10.60.60.90.90.9-0.70.70.91.0-0.70.90.90.00.9
Rest time, locomotor task time 10.30.30.80.50.5-0.90.30.50.7-0.90.40.5-0.30.5
Distance moved, locomotor task time 10.80.81.8-0.9-0.81.4-0.4-0.8-1.11.3-0.7-0.80.6-0.7
Vertical activity count, locomotor time 10.40.41.5-0.3-0.31.2-0.3-0.3-0.71.1-0.3-0.20.9-0.2
Time >=10cm from walls, locomotor time 20.80.92.01.01.00.90.81.00.40.70.81.01.41.0
Bouts of movement, locomotor time 20.50.51.5-0.6-0.61.1-0.3-0.6-1.01.2-0.4-0.60.6-0.5
Total resting periods, locomotor time 20.60.61.1-0.8-0.80.9-0.6-0.8-1.01.0-0.7-0.80.1-0.7
Rest time, locomotor task time 21.72.04.7-1.3-1.3-1.5-1.5-1.3-0.5-1.1-1.5-1.3-2.2-1.5
Distance moved, locomotor task time 21.71.96.11.11.02.01.31.00.21.51.21.12.51.3
Vertical activity count, locomotor time 20.70.83.20.20.21.80.10.2-0.51.50.20.21.70.3
Weight adjusted by age0.50.51.7-0.4-0.41.3-0.3-0.4-0.81.3-0.4-0.20.9-0.2
Seeking ratio, delayed vs. immediate footshock0.50.62.5-0.3-0.4-1.6-0.6-0.30.3-1.2-0.2-0.2-1.3-0.3
Locomotion in novel chamber1.51.83.61.41.4-0.71.91.31.6-1.11.81.30.21.3
Locomotion in novel chamber post-restriction2.53.04.52.12.10.12.01.91.6-0.31.91.91.42.1
Progressive ratio0.20.30.50.50.5-0.40.70.40.6-0.50.50.6-0.10.5
Food seeking constrained by brief footshock0.50.62.7-0.1-0.11.70.2-0.2-0.61.40.1-0.11.20.1
Seeking ratio, punishment vs. effort0.91.13.3-0.5-0.51.8-0.6-0.5-1.21.8-0.5-0.71.2-0.4
Run reversals in cocaine runway, females5.05.07.7-2.3-2.22.0-2.6-2.3-2.82.4-2.4-2.20.4-2.1
Run reversals in cocaine runway, males0.00.00.10.00.0-0.3-0.30.00.1-0.3-0.20.0-0.30.0
Latency to leave start box in cocaine runway3.23.55.5-2.3-2.2-0.2-2.2-2.0-1.80.3-2.3-2.0-1.3-2.2
Latency to leave start box in cocaine runway, F3.94.26.3-2.5-2.50.5-2.3-2.2-2.21.0-2.5-2.2-1.0-2.4
Latency to leave start box in cocaine runway, M0.20.21.00.00.0-1.0-0.10.00.4-0.9-0.10.0-0.7-0.1
Cd content in liver1.11.21.6-1.3-1.20.4-1.2-1.2-1.20.7-1.2-1.3-0.5-1.2
Co content in liver0.70.83.00.30.31.70.30.3-0.51.50.20.41.70.4
Cu content in liver0.60.72.7-0.2-0.21.6-0.2-0.2-0.81.6-0.1-0.01.3-0.0
Fe content in liver0.10.10.1-0.3-0.30.2-0.3-0.3-0.30.3-0.4-0.2-0.1-0.3
K content in liver0.50.50.7-0.8-0.80.4-0.8-0.8-0.80.6-0.8-0.6-0.2-0.8
Mg content in liver0.10.10.20.10.10.50.10.1-0.10.40.10.20.50.2
Mn content in liver0.70.93.4-0.1-0.1-1.8-0.1-0.10.6-1.7-0.1-0.1-1.6-0.3
Na content in liver0.30.30.50.60.60.00.60.60.5-0.10.60.70.60.6
Rb content in liver0.40.51.20.60.60.90.60.60.10.70.50.61.10.7
Se content in liver1.72.15.2-1.4-1.4-1.7-1.4-1.4-0.5-1.2-1.4-1.1-2.3-1.5
Sr content in liver0.30.30.50.50.5-0.60.50.50.7-0.70.40.6-0.10.5
Zn content in liver2.83.16.71.81.71.61.71.70.91.11.81.82.62.0