Hub : Genes

Pgm2l1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000017079 0.19 0.1 1.5e-14 0.12 0.11 0.11 0.12 2.0e-13 5.3e-12 4.9e-12 4.5e-13
2 Adipose mRNA stability ENSRNOG00000017079 0.05 0.03 5.5e-05 0.02 0.04 0.04 0.03 3.8e-03 6.4e-05 6.0e-05 2.4e-04
3 BLA gene expression ENSRNOG00000017079 0.51 0.15 0.0e+00 0.37 0.37 0.38 0.37 1.1e-20 4.2e-21 4.0e-21 5.9e-21
4 BLA mRNA stability ENSRNOG00000017079 0.21 0.12 2.0e-06 0.11 0.1 0.09 0.09 2.6e-06 9.1e-06 1.7e-05 1.9e-05
5 Brain gene expression ENSRNOG00000017079 0.55 0.17 0.0e+00 0.43 0.5 0.5 0.5 7.1e-43 2.7e-52 1.4e-52 2.1e-52
6 Brain mRNA stability ENSRNOG00000017079 0.12 0.08 6.3e-07 0.07 0.07 0.08 0.07 2.3e-07 3.2e-07 1.6e-07 3.7e-07
7 IL gene expression ENSRNOG00000017079 0.61 0.16 8.7e-09 0.09 0.13 0.1 0.1 2.9e-03 6.2e-04 1.9e-03 2.5e-03
8 Liver mRNA stability ENSRNOG00000017079 0.04 0.03 4.0e-03 0.01 0 0 0 9.5e-03 1.2e-01 9.3e-02 1.1e-01
9 NAcc gene expression ENSRNOG00000017079 0.26 0.13 1.6e-11 0.12 0.12 0.12 0.06 2.4e-09 3.8e-09 6.3e-09 3.5e-05
10 NAcc mRNA stability ENSRNOG00000017079 0.08 0.06 7.8e-04 0.05 0.04 0.04 0.04 2.0e-04 8.6e-04 3.7e-04 3.9e-04
11 OFC gene expression ENSRNOG00000017079 0.44 0.19 1.4e-06 0.18 0.2 0.19 0.21 4.4e-05 1.8e-05 2.5e-05 9.5e-06
12 OFC mRNA stability ENSRNOG00000017079 0.23 0.15 7.8e-03 0.01 0.04 0.01 0.02 1.5e-01 3.3e-02 1.4e-01 1.2e-01
13 PL gene expression ENSRNOG00000017079 0.47 0.16 0.0e+00 0.35 0.37 0.4 0.18 2.1e-27 3.4e-29 2.2e-32 9.3e-14
14 PL mRNA stability ENSRNOG00000017079 0.18 0.11 3.6e-08 0.1 0.09 0.11 0.1 3.1e-08 3.3e-07 1.9e-08 2.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.00.10.60.00.10.2-0.80.3-0.30.3-0.0-0.1-0.60.5-0.50.2-0.5
BMI without tail1.32.77.4-1.4-0.2-0.3-2.7-0.3-2.10.0-1.3-1.4-2.70.6-2.5-0.5-2.4
Body weight0.83.310.1-1.2-0.00.0-3.20.0-2.20.4-1.2-1.3-3.11.0-2.8-0.2-2.7
Epididymis fat weight0.61.53.20.51.01.3-1.81.2-0.71.40.30.1-1.81.7-1.40.9-1.4
Glucose0.00.10.1-0.0-0.1-0.20.4-0.20.1-0.3-0.1-0.10.3-0.40.3-0.10.3
Heart weight1.01.52.4-1.3-1.3-1.6-0.3-1.5-1.1-1.5-1.4-1.3-0.3-1.5-0.7-1.5-0.7
Left kidney weight1.33.87.6-1.8-1.0-1.1-2.6-1.2-2.6-0.8-2.0-2.2-2.6-0.4-2.8-1.4-2.6
Right kidney weight0.82.34.7-1.3-0.7-0.8-2.1-0.9-2.1-0.5-1.5-1.6-2.1-0.2-2.2-0.9-2.0
Tail length3.410.222.6-3.2-1.2-1.4-4.7-1.4-4.1-0.8-3.0-3.2-4.80.1-4.7-1.8-4.5
Length with tail1.65.715.5-2.2-0.5-0.5-3.8-0.4-3.0-0.0-1.9-2.1-3.90.7-3.7-0.8-3.5
Length without tail0.20.40.60.70.50.70.30.80.60.60.70.80.30.70.50.80.5
Liver weight, left0.71.22.60.30.91.2-1.51.2-0.41.30.40.4-1.51.6-1.01.0-1.1
Liver weight, right1.62.66.10.51.51.8-2.11.8-0.52.10.60.6-2.22.5-1.51.6-1.4
Parametrial fat weight0.81.53.70.81.31.7-1.01.70.31.71.00.7-1.11.9-0.61.2-0.8
Retroperitoneal fat weight2.89.324.11.63.03.7-3.53.8-0.44.11.71.6-3.44.9-2.33.3-2.1
Intraocular pressure0.20.30.9-0.1-0.5-0.60.7-0.70.2-0.7-0.2-0.20.7-0.90.6-0.50.7
Extensor digitorum longus weight0.20.82.30.00.60.7-1.50.7-0.70.9-0.1-0.1-1.51.2-1.20.5-1.1
Soleus weight0.72.06.2-0.40.60.7-2.50.7-1.31.0-0.4-0.4-2.51.5-2.10.4-2.0
Tibialis anterior weight0.20.61.6-0.6-0.2-0.2-1.3-0.2-1.0-0.1-0.7-0.7-1.20.2-1.2-0.4-1.1
Tibia length1.33.78.2-1.9-2.2-2.60.8-2.6-0.9-2.7-1.8-1.90.8-2.90.0-2.40.1
Number of licking bursts3.94.68.22.42.42.90.12.81.52.92.32.20.12.80.82.70.9
Food consumed during 24 hour testing period3.03.66.4-2.0-2.1-2.5-0.0-2.5-1.3-2.5-2.1-2.0-0.0-2.5-0.6-2.4-0.7
Times rat made contact with spout0.40.40.90.30.60.7-0.90.7-0.30.80.20.2-0.81.0-0.70.5-0.6
Mean time between licks in bursts5.98.312.6-3.2-2.1-2.3-3.2-2.3-3.5-2.0-3.2-3.3-3.2-1.2-3.5-2.6-3.5
Mean num. licks in bursts3.34.06.8-2.2-2.2-2.6-0.3-2.5-1.6-2.6-2.2-2.1-0.3-2.5-0.9-2.5-1.0
Std. dev. time between licks in bursts2.42.86.0-1.6-0.7-0.8-2.4-0.8-2.2-0.5-1.7-1.7-2.4-0.1-2.4-1.0-2.3
Water consumed over 24 hours0.60.71.01.00.80.90.70.80.90.80.91.00.70.60.90.90.9
Indifference point 0 sec3.65.89.1-2.6-2.6-2.9-0.9-2.9-2.3-2.8-2.7-2.8-0.9-2.7-1.6-3.0-1.7
Indifference point AUC0.40.51.5-0.50.10.2-1.20.1-0.80.3-0.6-0.6-1.20.4-1.1-0.1-0.9
Indifference point function ln k1.11.54.1-0.6-1.2-1.61.2-1.6-0.0-1.7-0.7-0.81.3-2.00.7-1.40.6
Indifference point function log k1.11.54.1-0.6-1.2-1.61.2-1.6-0.0-1.7-0.7-0.81.3-2.00.7-1.40.6
Delay discounting total patch changes 0 sec2.94.77.3-2.4-2.3-2.6-0.9-2.6-2.1-2.5-2.5-2.5-0.9-2.3-1.5-2.7-1.6
Delay discounting total patch changes 12 sec1.62.23.5-1.7-1.0-1.1-1.7-1.1-1.8-0.9-1.7-1.7-1.7-0.6-1.9-1.4-1.7
Delay discounting total patch changes 18 sec2.22.94.6-2.0-1.6-1.7-1.3-1.7-1.9-1.7-2.1-2.1-1.3-1.3-1.6-1.9-1.6
Delay discounting total patch changes 24 sec1.31.62.9-1.5-1.0-1.0-1.5-1.0-1.7-0.8-1.4-1.2-1.6-0.4-1.7-0.9-1.4
Delay discounting total patch changes 6 sec0.50.81.4-0.9-0.9-1.1-0.2-1.2-0.9-1.0-1.0-1.0-0.2-1.2-0.5-1.1-0.3
Delay discounting time to switch 0 sec3.45.27.82.82.12.61.32.52.32.42.62.81.22.21.92.72.0
Delay discounting water rate 0 sec2.74.36.8-2.4-2.1-2.6-0.7-2.5-1.8-2.5-2.3-2.3-0.6-2.3-1.3-2.6-1.4
Delay discounting water rate 12 sec1.62.44.5-1.8-1.8-2.10.1-2.0-1.0-2.1-1.5-1.50.0-2.0-0.5-2.0-0.5
Delay discounting water rate 18 sec1.11.52.7-1.6-1.2-1.5-0.8-1.3-1.3-1.3-1.3-1.2-0.7-1.1-1.1-1.3-1.0
Delay discounting water rate 24 sec0.91.33.6-0.9-1.1-1.51.0-1.5-0.0-1.6-0.7-0.81.0-1.90.5-1.30.5
Delay discounting water rate 6 sec0.81.12.3-1.2-1.2-1.50.4-1.4-0.5-1.5-1.0-0.90.3-1.5-0.1-1.30.0
Locomotor activity0.50.81.9-0.8-0.8-1.1-0.0-1.2-0.8-1.1-0.9-1.2-0.1-1.4-0.3-1.2-0.4
Locomotor testing distance1.93.14.6-1.9-1.6-2.0-1.1-2.0-1.9-1.8-2.0-2.1-1.1-1.8-1.5-2.1-1.5
Locomotor testing rearing1.01.62.8-1.2-0.6-0.8-1.6-0.8-1.6-0.6-1.2-1.5-1.6-0.4-1.7-1.0-1.7
Light reinforcement 12.13.86.62.52.12.60.82.51.82.32.31.90.72.31.22.00.8
Light reinforcement 20.40.61.11.00.50.61.00.61.00.40.80.71.00.21.00.40.8
Reaction time number correct0.60.82.60.3-0.1-0.51.6-0.41.0-0.50.50.21.6-1.01.4-0.41.2
Reaction time mean minus median0.71.01.8-1.0-0.8-0.9-0.8-0.8-1.0-0.9-1.1-1.4-0.8-0.6-1.1-1.1-1.2
Reaction time mean minus median AUC0.91.12.1-1.1-1.2-1.2-0.2-1.2-0.8-1.3-1.1-1.4-0.3-1.2-0.6-1.4-0.9
Reaction time num false alarms1.52.13.91.71.71.9-0.11.90.92.01.61.4-0.11.90.41.80.3
Reaction time num false alarms AUC0.81.21.91.41.21.40.11.40.81.41.21.10.21.30.41.30.4
Reaction time trials correct on left0.60.82.60.3-0.1-0.51.6-0.41.0-0.50.50.21.6-1.01.4-0.41.2
Reaction time trials on left0.60.92.70.4-0.1-0.41.6-0.41.0-0.50.50.21.6-1.01.4-0.41.2
Reaction time mean0.60.81.90.91.01.2-0.31.20.41.20.80.7-0.31.4-0.11.1-0.2
Reaction time mean AUC0.81.12.21.11.21.40.11.50.81.41.21.00.11.50.31.30.1
Median of all reaction times1.11.52.81.31.41.60.11.60.91.61.31.20.21.70.41.60.3
Reaction time omissions0.20.30.80.70.60.8-0.30.80.20.80.50.3-0.30.9-0.10.6-0.2
Reaction time false alarm rate1.01.43.31.21.31.6-0.61.60.41.71.01.1-0.61.8-0.21.6-0.1
Reaction time premature initiation rate2.33.16.3-1.7-1.0-0.9-2.5-0.9-2.3-0.7-1.9-1.9-2.5-0.1-2.5-1.1-2.4
Reaction time premature initiations1.21.72.7-1.4-1.0-1.2-1.3-1.2-1.5-1.0-1.5-1.7-1.3-0.8-1.5-1.3-1.5
Std. dev. reaction times0.60.82.2-0.6-0.1-0.1-1.4-0.1-1.20.1-0.8-0.9-1.50.4-1.5-0.3-1.4
Reaction time trials completed0.60.92.70.4-0.1-0.41.6-0.41.0-0.50.50.21.6-1.01.4-0.41.2
Reaction time trials AUC0.40.61.90.3-0.0-0.41.4-0.40.8-0.50.40.01.4-0.91.2-0.41.0
Social response proportion0.30.30.80.30.60.7-0.60.70.00.80.40.5-0.60.9-0.40.8-0.1
Social responses0.60.71.70.00.60.8-1.30.8-0.51.00.10.2-1.31.3-1.00.8-0.9
Social time2.83.75.72.01.72.11.42.12.21.82.42.21.41.71.82.01.6
Conditioned locomotion0.20.20.40.40.20.20.70.20.60.10.40.40.7-0.00.60.20.6
Cocaine response after cond. corrected1.51.63.61.21.41.7-0.51.70.61.81.31.2-0.41.90.01.60.0
Cocaine response after cond. not corrected0.40.41.00.70.70.9-0.10.90.40.90.70.7-0.11.00.10.80.1
Cocaine response before conditioning1.41.73.8-1.1-1.5-1.80.8-1.7-0.5-1.8-1.2-1.20.8-1.90.2-1.60.2
Saline control response2.12.83.9-2.0-1.5-1.6-1.4-1.6-1.9-1.5-1.9-1.9-1.4-1.2-1.7-1.7-1.7
Condit. Reinf. active minus inactive responses7.59.313.2-3.6-2.7-3.2-2.4-3.2-3.4-2.9-3.6-3.5-2.4-2.5-2.9-3.3-2.8
Condit. Reinf. active-inactive response ratio1.71.82.7-1.7-1.3-1.5-0.8-1.5-1.4-1.4-1.6-1.5-0.8-1.3-1.1-1.5-1.1
Condit. Reinf. active responses9.813.619.0-4.3-3.2-3.7-3.1-3.7-4.2-3.3-4.4-4.3-3.1-2.8-3.7-3.9-3.6
Condit. Reinf. inactive responses5.77.19.8-3.0-2.2-2.5-2.5-2.5-3.1-2.2-3.1-3.1-2.5-1.8-2.9-2.7-2.8
Condit. Reinf. lever presses16.522.832.0-5.7-4.7-5.4-2.8-5.4-4.9-5.0-5.6-5.5-2.9-4.5-3.9-5.4-3.8
Condit. Reinf. lever reinforcers received10.815.221.2-4.6-3.5-4.0-3.1-4.0-4.3-3.6-4.6-4.5-3.1-3.1-3.8-4.2-3.6
Pavlov. Cond. lever latency16.422.431.25.54.75.52.55.54.75.25.65.52.54.73.65.53.5
Pavlov. Cond. magazine entry latency3.43.96.4-2.2-2.2-2.5-0.4-2.5-1.6-2.5-2.2-2.2-0.4-2.4-1.0-2.5-0.9
Pavlov. Cond. change in total contacts12.317.124.5-4.8-4.2-5.0-1.8-4.9-3.9-4.7-4.9-4.7-1.8-4.4-2.8-4.9-2.7
Pavlov. Cond. index score12.516.322.8-4.7-4.1-4.8-1.9-4.7-3.9-4.5-4.7-4.7-1.9-4.2-2.9-4.8-2.8
Pavlov. Cond. latency score11.114.019.9-4.4-3.8-4.5-1.7-4.4-3.6-4.2-4.4-4.3-1.7-3.9-2.7-4.4-2.6
Pavlov. Cond. lever contacts17.023.632.9-5.7-4.8-5.6-2.6-5.6-4.8-5.3-5.7-5.6-2.6-4.9-3.7-5.7-3.6
Pavlov. Cond. magazine entry number6.17.612.23.13.03.50.63.52.33.43.13.10.63.31.43.41.4
Pavlov. Cond. intertrial magazine entries0.60.82.4-0.40.20.3-1.60.3-1.00.4-0.5-0.5-1.60.8-1.40.1-1.3
Pavlov. Cond. lever-magazine prob. diff.11.915.421.2-4.6-3.9-4.6-2.0-4.5-3.9-4.3-4.6-4.5-2.0-4.0-3.0-4.6-2.8
Pavlov. Cond. response bias17.023.432.5-5.6-4.9-5.7-2.3-5.7-4.7-5.4-5.7-5.6-2.4-5.0-3.5-5.7-3.4
Conditioned reinforcement - actives2.42.34.6-1.5-1.8-2.10.3-2.1-1.0-2.1-1.6-1.60.3-2.1-0.3-1.9-0.0
Conditioned reinforcement - inactives0.10.20.50.00.20.4-0.40.50.00.40.20.5-0.40.7-0.20.6-0.0
Conditioned locomotion2.12.56.1-1.4-1.7-2.20.8-2.2-0.7-2.2-1.5-1.50.8-2.50.2-1.60.5
Intermittent access intake day 1-15 change0.60.61.2-0.8-0.8-1.0-0.1-1.0-0.5-0.9-0.8-0.7-0.0-1.1-0.3-0.9-0.0
Intermittent access intake escalation0.70.71.6-0.9-0.8-1.1-0.1-1.1-0.6-1.0-0.8-0.80.0-1.3-0.3-1.0-0.0
Intermittent access intake escalation 20.30.30.7-0.5-0.2-0.5-0.7-0.6-0.7-0.3-0.5-0.8-0.6-0.5-0.7-0.5-0.4
Intermitt. access day 1 inactive lever presses0.30.31.00.30.40.7-0.40.70.10.70.30.7-0.41.0-0.10.9-0.1
Intermitt. access day 15 inactive lever presses0.10.10.3-0.3-0.6-0.40.4-0.30.1-0.5-0.3-0.00.4-0.40.3-0.10.5
Intermitt. access escalation Index0.30.30.6-0.6-0.5-0.6-0.1-0.6-0.4-0.6-0.4-0.7-0.1-0.8-0.3-0.6-0.1
Intermittent access day 1 total infusions1.11.32.1-1.4-1.3-1.3-0.6-1.2-1.1-1.3-1.4-1.2-0.7-0.9-0.9-1.2-0.8
Intermittent access day 15 total infusions1.41.62.8-1.5-1.5-1.7-0.3-1.6-1.0-1.6-1.5-1.3-0.2-1.6-0.6-1.4-0.3
Intermittent access terminal intake (last 3 days)1.41.52.3-1.4-1.3-1.5-0.5-1.5-1.2-1.5-1.5-1.3-0.4-1.4-0.8-1.4-0.5
Intermittent access total infusions1.01.12.1-1.4-1.3-1.3-0.5-1.2-1.0-1.2-1.4-1.0-0.5-0.9-0.7-1.0-0.5
Intermittent access day 1 locomotion0.10.10.2-0.2-0.4-0.40.3-0.30.0-0.5-0.3-0.00.2-0.40.2-0.10.3
Intermittent access day 15 total locomotion1.11.12.6-1.2-1.2-1.50.0-1.5-0.7-1.4-1.1-1.10.0-1.6-0.3-1.10.1
Intermittent access total locomotion0.60.61.1-0.9-0.9-1.0-0.2-1.0-0.7-1.0-1.0-0.9-0.2-0.9-0.4-0.8-0.3
Intermittent access standard deviation0.20.20.4-0.1-0.2-0.2-0.6-0.3-0.6-0.1-0.6-0.4-0.6-0.1-0.5-0.3-0.5
Cocaine induced anxiety1.92.23.92.01.51.80.61.71.31.71.81.50.61.51.01.71.0
Post-drug Anxiety0.80.91.70.91.11.2-0.11.20.51.31.20.8-0.11.20.21.30.3
Baseline Anxiety1.11.12.5-1.6-0.9-1.1-0.7-1.0-1.1-1.0-1.3-1.2-0.7-0.8-1.0-1.0-1.0
Lifetime Intake1.21.42.7-1.7-1.4-1.5-0.5-1.3-1.1-1.4-1.5-1.1-0.5-1.0-0.8-1.2-0.6
Incentive Sensitization - Responses2.62.65.4-1.8-1.2-1.7-1.1-1.7-1.9-1.4-1.9-2.3-1.1-1.4-1.6-1.7-1.2
Incentive Sensitization - Breakpoint2.32.34.9-1.7-1.2-1.6-0.9-1.7-1.7-1.4-1.8-2.2-0.9-1.5-1.4-1.7-1.1
Progressive ratio test 1 active lever presses0.10.10.30.20.10.40.10.40.30.30.30.50.20.50.20.60.4
Progressive ratio test 1 breakpoint0.10.10.30.10.10.3-0.10.40.10.30.20.4-0.10.50.00.50.2
Progressive ratio test 1 inactive lever presses0.30.30.8-0.9-0.8-0.5-0.5-0.3-0.5-0.6-0.7-0.4-0.50.0-0.6-0.4-0.6
Progressive ratio test 2 active lever presses1.11.12.4-1.2-0.9-1.0-0.7-1.1-1.2-1.0-1.3-1.5-0.7-0.9-1.0-1.1-0.8
Progressive ratio test 2 breakpoint1.11.22.5-1.3-0.9-1.1-0.8-1.1-1.3-1.0-1.4-1.6-0.8-0.9-1.1-1.2-0.9
Progressive ratio test 2 inactive lever presses0.70.81.6-1.0-1.1-1.10.1-1.0-0.6-1.3-1.1-0.90.1-1.0-0.3-1.1-0.2
Total sessions with >9 infusions2.02.24.3-2.0-1.9-2.0-0.1-1.8-1.0-2.1-1.6-1.1-0.1-1.7-0.6-1.8-0.5
Short access day 1 total inactive lever presses0.20.20.7-0.00.00.40.30.60.60.20.40.80.20.50.40.60.3
Short access day 10 total inactive lever presses0.10.10.30.40.20.20.40.20.30.20.40.60.30.00.40.40.5
Short access day 1 total infusions2.32.54.2-2.0-1.7-1.9-0.8-1.7-1.6-1.8-1.8-1.7-0.7-1.4-1.3-1.8-1.1
Short access day 10 total infusions1.51.72.8-1.7-1.3-1.3-1.0-1.3-1.6-1.2-1.7-1.2-1.1-0.8-1.3-1.2-1.1
Short access total infusions1.01.22.6-1.6-1.2-1.2-0.7-1.0-1.1-1.2-1.3-1.0-0.7-0.6-1.0-1.1-1.0
Short access day 1 locomotion1.31.43.2-1.2-1.4-1.70.6-1.5-0.3-1.8-1.1-1.00.7-1.70.2-1.50.2
Short access day 10 total locomotion0.40.40.9-0.6-0.4-0.7-0.6-0.8-1.0-0.5-0.8-0.8-0.6-0.7-0.7-0.5-0.3
Short access total locomotion0.10.10.2-0.4-0.3-0.5-0.1-0.5-0.3-0.5-0.4-0.3-0.1-0.4-0.2-0.3-0.0
Compulsive drug intake0.30.31.00.4-0.0-0.01.0-0.00.7-0.10.50.41.0-0.40.8-0.10.7
One hour access (0.3 mA shock)2.02.33.8-1.9-1.6-1.9-0.9-1.8-1.6-1.7-2.0-1.5-0.8-1.6-1.1-1.6-0.7
One hour access (shock baseline)1.72.03.4-1.8-1.3-1.6-1.1-1.6-1.6-1.4-1.8-1.6-1.1-1.3-1.3-1.3-0.9
Number of responses in last shaping day0.40.40.8-0.6-0.3-0.4-0.9-0.4-0.9-0.3-0.7-0.8-0.8-0.1-0.9-0.5-0.9
Context. condit. distance diff. score1.82.24.3-1.5-1.7-2.00.2-2.0-0.9-2.0-1.5-1.50.3-2.1-0.2-1.9-0.2
Locomotion velocity, session 10.50.61.40.70.20.21.20.20.90.10.70.71.2-0.11.10.31.1
Locomotion distance, session 10.60.81.8-0.8-1.0-1.20.5-1.2-0.3-1.2-0.8-0.80.5-1.30.1-1.10.1
Locomotion velocity, session 20.10.10.1-0.3-0.2-0.3-0.2-0.3-0.3-0.2-0.3-0.3-0.2-0.2-0.3-0.3-0.2
Locomotion distance, session 20.30.40.9-0.7-0.7-0.90.1-0.9-0.4-0.9-0.7-0.70.2-1.0-0.1-0.8-0.0
Locomotion velocity, session 30.50.61.6-0.4-0.8-1.00.8-1.0-0.1-1.1-0.6-0.60.8-1.30.4-0.90.5
Locomotion distance, session 31.01.12.8-0.7-1.1-1.40.9-1.4-0.2-1.5-0.8-0.80.9-1.70.5-1.30.5
Stereotopy head waving bouts, day 30.30.40.90.40.60.8-0.60.8-0.00.80.40.4-0.60.9-0.40.6-0.4
Stereotopy head waving duration, day 30.10.10.2-0.1-0.3-0.30.3-0.30.0-0.4-0.1-0.10.3-0.40.2-0.30.2
Locomotion velocity, session 70.30.30.50.70.40.50.60.50.70.40.60.60.60.30.70.50.7
Locomotion distance, session 70.10.10.20.40.40.5-0.10.50.20.50.40.4-0.00.50.10.40.2
Stereotopy head waving bouts, day 72.02.24.1-1.6-1.7-2.00.1-2.0-1.0-2.0-1.6-1.60.1-2.0-0.4-1.9-0.4
Stereotopy head waving duration, day 72.53.05.0-1.9-1.9-2.2-0.3-2.2-1.4-2.2-2.0-2.0-0.3-2.1-0.8-2.2-0.8
Locomotion velocity, session 80.50.71.2-0.8-0.9-1.1-0.0-1.1-0.6-1.1-0.9-0.9-0.0-1.1-0.3-1.0-0.2
Locomotion distance, session 81.82.74.7-1.8-1.8-2.2-0.1-2.1-1.2-2.1-1.8-1.8-0.1-2.1-0.6-2.0-0.5
Degree of sensitization distance1.21.22.90.20.81.1-1.71.1-0.51.20.20.2-1.71.6-1.20.9-1.2
Degree of sensitization stereotypy4.54.98.5-2.4-2.5-2.9-0.0-2.9-1.6-2.9-2.4-2.40.0-2.9-0.7-2.8-0.7
Condit. Reinf. active minus inactive responses0.40.41.0-0.6-0.2-0.3-1.0-0.3-0.8-0.2-0.6-0.6-1.00.0-1.0-0.4-0.9
Condit. Reinf. active-inactive response ratio0.80.91.7-1.0-0.5-0.6-1.3-0.6-1.2-0.4-1.0-1.0-1.3-0.2-1.3-0.7-1.2
Condit. Reinf. active responses0.10.10.3-0.20.00.0-0.50.0-0.40.1-0.2-0.2-0.50.2-0.5-0.0-0.4
Condit. Reinf. inactive responses0.10.10.10.30.20.20.30.20.30.20.30.30.30.10.30.20.3
Incentive salience index mean0.40.40.9-0.7-0.3-0.4-0.9-0.4-0.9-0.3-0.7-0.7-0.9-0.2-0.9-0.5-0.8
Condit. Reinf. lever presses0.10.10.2-0.4-0.2-0.3-0.4-0.4-0.5-0.3-0.5-0.5-0.4-0.2-0.4-0.4-0.4
Time in familiar zone, hab. session 10.10.10.4-0.20.10.1-0.60.1-0.30.2-0.1-0.1-0.60.3-0.50.1-0.4
Time in novel zone, hab. session 10.20.20.30.60.50.60.10.50.40.60.50.50.20.50.30.50.2
Total zone transitions, hab. session 10.20.31.00.2-0.2-0.21.0-0.20.6-0.30.20.21.0-0.50.9-0.10.9
Total locomotion distance, hab. session 10.71.02.50.40.91.2-1.31.2-0.31.30.50.5-1.31.6-0.91.0-0.8
Locomotion velocity, hab. session 10.40.61.40.20.70.9-1.10.9-0.21.00.30.3-1.01.2-0.70.7-0.6
Time in familiar zone, hab. session 21.51.62.2-1.5-1.2-1.3-1.0-1.3-1.4-1.2-1.5-1.5-0.9-1.0-1.2-1.3-1.0
Time in novel zone, hab. session 20.50.50.70.80.50.60.80.60.80.50.80.80.80.30.80.60.7
Total zone transitions, hab. session 21.01.33.0-1.1-1.3-1.60.5-1.6-0.5-1.6-1.1-1.10.5-1.70.1-1.40.0
Total locomotion distance, hab. session 20.60.82.6-0.50.10.2-1.60.2-1.00.4-0.5-0.5-1.60.7-1.40.1-1.4
Locomotion velocity, hab. session 20.71.03.1-0.40.30.4-1.80.4-1.00.6-0.4-0.4-1.71.0-1.50.2-1.5
Novel to familiar place preference ratio0.10.10.1-0.3-0.3-0.30.0-0.3-0.1-0.3-0.2-0.20.0-0.3-0.0-0.3-0.1
Novelty place preference0.10.10.1-0.3-0.3-0.30.1-0.3-0.1-0.3-0.2-0.20.0-0.3-0.0-0.3-0.1
Time in novel zone, NPP test0.20.20.3-0.4-0.5-0.50.0-0.5-0.3-0.5-0.4-0.40.0-0.5-0.1-0.6-0.2
Total zone transitions, NPP test0.20.30.7-0.3-0.5-0.70.6-0.70.1-0.7-0.3-0.30.6-0.80.4-0.60.4
Total locomotion distance, NPP test0.50.71.50.10.70.8-1.20.8-0.41.00.20.2-1.21.2-0.90.7-0.9
Locomotion velocity, NPP test0.60.92.20.51.01.2-1.11.2-0.11.30.50.5-1.11.5-0.71.0-0.7
Pavlov. Cond. lever latency1.21.52.21.41.21.40.71.41.31.31.51.50.81.21.01.41.0
Pavlov. Cond. magazine entry latency2.93.75.1-2.2-1.8-2.1-1.2-2.1-2.0-2.0-2.3-2.3-1.2-1.7-1.7-2.2-1.7
Pavlov. Cond. change in total contacts1.41.52.1-1.4-1.2-1.4-0.8-1.3-1.3-1.3-1.5-1.5-0.9-1.1-1.1-1.4-1.1
Pavlov. Cond. index score3.03.85.3-2.2-1.8-2.1-1.3-2.1-2.1-2.0-2.3-2.3-1.3-1.7-1.7-2.2-1.7
Pavlov. Cond. latency score2.83.65.1-2.1-1.8-2.1-1.2-2.1-2.0-2.0-2.3-2.3-1.2-1.7-1.7-2.2-1.6
Pavlov. Cond. lever contacts1.41.62.3-1.4-1.1-1.3-1.1-1.3-1.5-1.2-1.5-1.5-1.1-1.0-1.3-1.4-1.3
Pavlov. Cond. magazine entry number3.24.05.52.32.02.31.02.32.02.22.32.31.12.01.62.31.6
Pavlov. Cond. intertrial magazine entries1.01.21.71.21.01.20.81.21.21.11.31.30.81.01.01.31.1
Pavlov. Cond. lever-magazine prob. diff.2.43.04.2-2.0-1.6-1.9-1.1-1.9-1.8-1.8-2.0-2.0-1.1-1.5-1.5-1.9-1.5
Pavlov. Cond. response bias1.31.62.2-1.4-1.1-1.3-1.0-1.3-1.4-1.2-1.5-1.5-1.0-1.0-1.2-1.4-1.2
Bone: apparent density0.20.30.80.40.20.10.80.10.60.10.40.40.9-0.20.80.20.8
Bone surface0.61.11.6-1.3-1.1-1.3-0.5-1.2-1.0-1.2-1.3-1.2-0.5-1.1-0.8-1.2-0.7
Bone volume0.40.61.0-0.9-0.8-1.0-0.3-1.0-0.7-0.9-0.9-0.9-0.2-0.9-0.5-1.0-0.4
Bone: connectivity density0.20.31.00.1-0.2-0.31.0-0.30.5-0.40.10.21.0-0.60.8-0.20.8
Bone: cortical apparent density1.51.93.81.41.61.8-0.31.80.81.91.51.4-0.31.90.11.80.3
Bone: cortical area0.40.71.1-0.9-0.6-0.6-1.0-0.6-1.0-0.5-0.9-0.9-0.9-0.4-1.0-0.7-0.9
Bone: cortical porosity0.80.81.9-0.7-1.0-1.20.7-1.2-0.2-1.3-0.7-0.70.6-1.40.3-1.20.3
Bone: cortical porosity0.60.71.7-0.6-0.9-1.10.7-1.1-0.1-1.2-0.6-0.60.7-1.30.4-1.00.4
Bone: cortical thickness0.10.20.30.50.40.40.30.40.50.40.60.40.40.30.40.40.5
Bone: cortical thickness0.10.20.4-0.3-0.4-0.50.4-0.5-0.0-0.5-0.2-0.30.4-0.60.2-0.40.3
Bone: cortical tissue density1.51.93.61.41.61.8-0.31.80.81.91.51.4-0.21.90.21.80.3
Bone: elastic displacement2.42.84.02.01.41.61.51.61.91.52.01.91.51.21.71.61.6
Bone: elastic work2.33.04.32.01.31.51.81.52.11.32.02.01.81.02.01.52.0
Bone: endosteal estimation1.63.55.5-2.1-1.3-1.4-2.2-1.4-2.3-1.2-2.1-2.0-2.2-0.7-2.3-1.5-2.3
Bone: endosteal perimeter2.04.15.8-2.3-1.5-1.7-2.1-1.7-2.4-1.5-2.4-2.3-2.1-1.1-2.4-1.8-2.3
Bone: final force0.00.00.00.10.10.2-0.10.20.00.20.20.1-0.10.2-0.00.20.1
Bone: final moment0.00.00.1-0.2-0.1-0.1-0.3-0.1-0.2-0.1-0.1-0.2-0.3-0.0-0.2-0.1-0.2
Bone: marrow area1.43.05.0-1.9-1.1-1.2-2.1-1.2-2.1-1.0-1.9-1.8-2.2-0.5-2.2-1.3-2.2
Bone: maximum diameter1.83.44.9-2.1-1.5-1.8-1.7-1.7-2.1-1.6-2.1-2.2-1.7-1.2-2.0-1.9-1.8
Bone: maximum force0.00.00.1-0.2-0.1-0.1-0.2-0.1-0.2-0.1-0.1-0.3-0.2-0.1-0.2-0.2-0.1
Bone: maximum moment0.10.20.3-0.5-0.4-0.4-0.3-0.4-0.5-0.4-0.4-0.5-0.3-0.3-0.4-0.4-0.3
Bone: minimum diameter1.12.05.4-1.2-0.3-0.3-2.3-0.3-1.8-0.1-1.2-1.2-2.30.4-2.2-0.5-2.1
Bone: periosteal estimation1.42.84.4-1.9-1.2-1.3-1.9-1.3-2.1-1.1-1.9-1.9-1.9-0.7-2.1-1.5-2.0
Bone: periosteal perimeter1.52.53.5-1.8-1.2-1.4-1.6-1.4-1.9-1.2-1.8-1.8-1.6-0.9-1.8-1.6-1.8
Bone: post-yield work0.10.20.3-0.5-0.4-0.5-0.1-0.5-0.4-0.5-0.5-0.5-0.1-0.5-0.3-0.4-0.3
Bone: stiffness0.20.30.70.20.50.7-0.80.7-0.10.80.30.2-0.80.9-0.50.7-0.4
Bone: tissue strength1.11.03.10.80.10.11.70.11.2-0.10.80.81.8-0.41.60.21.5
Bone: trabecular number1.01.62.51.40.91.01.41.01.50.91.41.41.50.51.51.11.6
Bone: trabecular spacing0.70.91.5-1.2-1.0-1.2-0.2-1.1-0.8-1.2-1.0-1.1-0.3-1.0-0.5-1.2-0.6
Bone: trabecular thickness0.20.20.40.60.60.6-0.10.60.30.60.50.4-0.00.60.10.60.1
Bone: trabecular tissue density1.21.74.00.81.41.6-1.41.6-0.11.80.90.7-1.42.0-0.91.4-0.8
Breakpoint value in progressive ratio session0.40.41.10.70.30.41.10.30.80.20.60.50.90.10.90.30.7
Distance traveled before self-admin0.91.02.11.51.21.30.21.10.61.41.20.90.21.10.51.00.6
Distance traveled after self-admin1.01.13.01.00.30.31.40.31.30.20.81.11.6-0.21.60.71.7
Delta time in closed arm before/after self-admin1.81.73.90.61.31.5-1.61.5-0.51.80.50.2-1.72.0-1.21.2-1.0
Delta time in open arm before/after self-admin3.23.14.8-2.2-1.9-2.1-0.8-2.0-1.6-2.1-2.1-1.9-0.8-1.8-1.2-2.0-1.4
Diff in mean of infusions in LGA sessions2.73.15.11.71.92.20.42.21.42.32.12.00.32.10.82.31.0
Extinction: sum of active levers before priming0.10.10.20.40.30.4-0.00.30.10.30.10.1-0.10.40.00.3-0.1
Active lever presses in extinction session 62.22.16.1-0.7-1.5-1.91.4-1.9-0.1-2.0-0.9-1.11.3-2.50.8-1.80.5
Delta distance traveled before/after self-admin0.91.02.3-1.1-1.3-1.40.4-1.2-0.2-1.5-1.0-0.50.5-1.40.3-0.80.4
Delta ambulatory time before/after self-admin1.01.12.6-1.0-1.4-1.40.8-1.30.1-1.6-1.0-0.40.9-1.50.6-0.80.6
Time in closed arm before self-admin1.92.15.6-0.7-1.5-1.91.5-1.80.3-2.1-0.7-0.61.6-2.41.1-1.41.1
Time in closed arm after self-admin1.11.22.61.40.60.71.20.71.20.61.21.21.20.21.41.01.6
Time in open arm before self-admin3.23.46.82.02.32.50.22.41.22.62.11.50.12.30.62.10.5
Time in open arm after self-admin0.91.02.6-0.9-0.2-0.2-1.4-0.2-1.2-0.0-0.9-1.1-1.40.2-1.5-0.5-1.6
Sum of active levers in priming session hrs 5-60.20.20.70.60.30.20.80.10.50.20.40.20.7-0.20.7-0.10.4
Time to tail flick, vehicle, before self-admin0.10.10.20.40.10.10.4-0.00.30.10.20.20.4-0.30.40.20.5
Time to tail flick, vehicle, after self-admin1.71.84.0-1.6-1.8-1.9-0.0-1.7-0.6-2.0-1.4-1.00.1-1.7-0.3-1.7-0.5
Time to tail flick, test, before self-admin0.50.51.0-0.8-0.5-0.5-0.9-0.4-0.9-0.4-0.9-0.7-1.00.0-0.9-0.5-1.0
Time to tail flick, test, after self-admin1.01.02.6-1.1-0.3-0.3-1.6-0.3-1.3-0.1-0.9-0.9-1.60.1-1.5-0.3-1.4
Delta time to tail flick, vehicle, before/after SA1.21.22.5-1.4-1.5-1.4-0.3-1.2-0.6-1.6-1.2-0.9-0.1-1.1-0.5-1.4-0.7
Delta time to tail flick, test, before/after SA0.20.20.40.30.50.6-0.10.60.30.60.50.4-0.00.50.10.60.2
Ambulatory time before self-admin1.11.12.11.41.11.20.51.10.81.31.21.10.51.00.81.11.0
Ambulatory time after self-admin1.21.34.00.9-0.1-0.01.7-0.01.3-0.20.61.01.8-0.61.80.52.0
Total heroin consumption0.20.30.6-0.4-0.5-0.70.6-0.60.0-0.8-0.3-0.50.4-0.80.2-0.80.0
Area under the delay curve0.00.00.10.20.30.3-0.20.2-0.20.30.0-0.2-0.30.2-0.20.0-0.3
Delay disc. indifference point, 0s delay0.80.81.3-1.0-0.8-1.0-0.6-1.0-1.1-0.9-1.1-1.1-0.7-0.8-0.8-1.0-0.7
Delay disc. indifference point, 16s delay0.10.10.20.40.20.20.40.10.30.20.30.20.30.00.40.20.4
Delay disc. indifference point, 2s delay1.01.11.9-1.0-0.6-0.7-1.2-0.7-1.4-0.5-1.2-1.3-1.2-0.4-1.4-0.9-1.4
Delay disc. indifference point, 24s delay0.80.81.41.20.91.00.71.00.91.01.00.90.60.80.81.00.8
Delay disc. indifference point, 4s delay1.21.22.4-1.1-0.5-0.6-1.4-0.7-1.5-0.4-1.2-1.3-1.5-0.3-1.5-0.9-1.3
Delay disc. indifference point, 8s delay0.00.00.30.10.0-0.00.0-0.1-0.2-0.0-0.1-0.5-0.1-0.2-0.2-0.3-0.3
Delay discount exponential model param0.10.10.1-0.3-0.3-0.30.2-0.30.1-0.3-0.10.20.2-0.30.2-0.10.2
Delay discount hyperbolic model param0.10.10.30.0-0.2-0.10.4-0.10.4-0.20.20.50.5-0.20.50.20.5
Fecal boli incidents, locomotor time 10.70.72.1-0.6-0.9-1.10.6-1.2-0.2-1.2-0.7-0.70.5-1.40.3-1.10.3
Change in fecal boli incidents, locomotor task1.00.91.70.90.91.1-0.01.20.71.21.01.20.11.30.41.30.6
Time >=10cm from walls, locomotor time 11.41.43.0-1.2-1.3-1.60.2-1.5-0.5-1.7-1.1-1.30.3-1.7-0.2-1.5-0.3
Bouts of movement, locomotor time 10.20.20.4-0.4-0.4-0.60.1-0.6-0.1-0.6-0.4-0.50.2-0.6-0.0-0.6-0.1
Total resting periods, locomotor time 10.20.20.6-0.1-0.4-0.50.7-0.40.4-0.6-0.00.00.8-0.60.6-0.30.4
Rest time, locomotor task time 10.30.30.90.30.00.10.80.20.8-0.10.50.41.0-0.10.80.20.7
Distance moved, locomotor task time 10.60.61.7-0.6-0.1-0.1-1.3-0.2-1.10.1-0.7-0.8-1.30.2-1.3-0.3-1.1
Vertical activity count, locomotor time 10.50.61.2-0.8-0.4-0.4-1.0-0.3-1.0-0.3-0.7-0.8-1.0-0.0-1.1-0.5-1.0
Time >=10cm from walls, locomotor time 21.41.42.2-1.5-1.3-1.4-0.7-1.3-1.2-1.3-1.4-1.4-0.7-1.1-1.0-1.4-0.9
Bouts of movement, locomotor time 20.70.81.9-0.8-0.2-0.3-1.3-0.4-1.2-0.1-1.0-0.7-1.40.1-1.3-0.4-1.1
Total resting periods, locomotor time 20.40.41.3-0.40.10.0-1.1-0.0-0.80.2-0.6-0.3-1.10.4-1.0-0.1-0.9
Rest time, locomotor task time 23.13.65.42.11.72.21.12.32.02.02.32.21.12.01.52.11.4
Distance moved, locomotor task time 23.54.16.4-2.2-1.8-2.1-1.5-2.1-2.2-1.9-2.3-2.5-1.4-1.7-1.9-2.3-1.8
Vertical activity count, locomotor time 21.61.82.9-1.5-1.0-1.1-1.4-1.1-1.6-1.0-1.5-1.7-1.3-0.7-1.6-1.3-1.6
Weight adjusted by age0.80.92.1-1.0-0.5-0.5-1.2-0.5-1.2-0.3-1.0-1.1-1.2-0.0-1.3-0.7-1.4
Seeking ratio, delayed vs. immediate footshock1.71.93.31.40.91.31.21.41.71.01.71.81.31.11.51.41.4
Locomotion in novel chamber0.80.93.3-0.2-0.7-1.21.0-1.4-0.1-1.1-0.6-0.61.0-1.80.7-1.10.6
Locomotion in novel chamber post-restriction1.61.94.1-1.4-1.6-1.90.2-1.9-0.7-2.0-1.4-1.10.3-2.0-0.2-1.6-0.1
Progressive ratio0.10.10.40.2-0.2-0.20.6-0.20.3-0.3-0.0-0.00.6-0.40.4-0.30.3
Food seeking constrained by brief footshock1.31.52.7-1.1-0.7-0.9-1.4-1.0-1.6-0.7-1.4-1.4-1.4-0.5-1.6-1.3-1.5
Seeking ratio, punishment vs. effort1.31.63.5-1.3-0.4-0.6-1.9-0.6-1.7-0.3-1.2-1.2-1.90.0-1.8-0.7-1.7
Run reversals in cocaine runway, females2.12.15.7-0.30.81.1-2.41.1-1.11.3-0.2-0.1-2.42.0-2.00.7-2.0
Run reversals in cocaine runway, males0.10.10.20.30.10.30.20.30.40.20.30.40.20.30.30.30.3
Latency to leave start box in cocaine runway2.22.45.51.21.72.1-0.32.20.92.11.61.5-0.42.30.11.90.1
Latency to leave start box in cocaine runway, F1.82.05.50.91.51.9-1.01.90.32.01.11.1-1.12.3-0.51.7-0.6
Latency to leave start box in cocaine runway, M0.60.61.00.70.50.51.00.61.00.50.90.90.90.31.00.60.9
Cd content in liver0.50.51.30.50.80.9-0.70.90.01.00.50.5-0.71.2-0.40.8-0.4
Co content in liver1.72.12.9-1.7-1.1-1.2-1.5-1.2-1.7-1.1-1.6-1.7-1.5-0.7-1.7-1.3-1.7
Cu content in liver1.21.52.7-1.3-0.7-0.8-1.6-0.8-1.5-0.6-1.3-1.3-1.6-0.3-1.6-0.9-1.6
Fe content in liver0.00.00.10.10.20.2-0.30.2-0.00.20.10.1-0.20.3-0.20.2-0.2
K content in liver0.20.20.50.30.40.6-0.60.6-0.00.60.30.3-0.50.7-0.30.5-0.3
Mg content in liver0.20.20.2-0.5-0.3-0.4-0.4-0.3-0.4-0.3-0.4-0.5-0.4-0.2-0.5-0.4-0.5
Mn content in liver1.92.23.41.71.01.11.71.11.81.01.61.71.70.61.81.31.8
Na content in liver0.20.20.4-0.4-0.6-0.60.1-0.6-0.3-0.6-0.5-0.40.1-0.6-0.1-0.6-0.1
Rb content in liver0.81.01.5-1.2-0.8-1.0-0.7-1.0-1.0-1.0-1.1-1.2-0.7-0.9-0.9-1.1-0.9
Se content in liver3.34.05.62.41.92.31.22.22.12.12.42.41.21.81.72.31.7
Sr content in liver0.20.20.50.2-0.1-0.10.7-0.00.6-0.20.30.20.7-0.40.6-0.10.6
Zn content in liver4.44.96.8-2.6-2.3-2.6-1.1-2.5-2.2-2.5-2.6-2.6-1.0-2.2-1.6-2.6-1.6