Hub : Genes

Coq7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000017012 0.13 0.07 2.0e-07 0.06 0.05 0.04 0.05 4.7e-07 1.6e-06 2.7e-05 2.7e-06
2 BLA mRNA stability ENSRNOG00000017012 0.13 0.07 1.7e-06 0.06 0.11 0.09 0.09 2.8e-04 2.2e-06 1.2e-05 9.6e-06
3 Brain gene expression ENSRNOG00000017012 0.15 0.08 3.7e-09 0.1 0.1 0.09 0.09 2.4e-09 4.0e-09 1.5e-08 5.8e-09
4 Brain mRNA stability ENSRNOG00000017012 0.37 0.13 0.0e+00 0.25 0.25 0.26 0.26 7.6e-23 4.0e-23 4.8e-24 4.9e-24
5 Eye intron excision ratio chr1:172841200:172851026 0.42 0.16 1.7e-03 0.09 0.05 0.05 0.05 1.7e-02 6.5e-02 6.2e-02 5.6e-02
6 IL gene expression ENSRNOG00000017012 0.29 0.14 1.4e-03 0.11 0.07 0.04 0.09 1.7e-03 8.8e-03 3.6e-02 3.8e-03
7 IL mRNA stability ENSRNOG00000017012 0.26 0.12 1.5e-04 0.13 0.14 0.12 0.13 4.8e-04 2.8e-04 1.0e-03 5.2e-04
8 LHb mRNA stability ENSRNOG00000017012 0.2 0.11 5.5e-03 0.01 0.01 -0.01 0 1.5e-01 1.6e-01 4.8e-01 3.3e-01
9 Liver gene expression ENSRNOG00000017012 0.04 0.03 5.1e-04 0.01 0.01 0.01 0.01 2.5e-02 1.4e-02 3.1e-02 3.5e-02
10 NAcc gene expression ENSRNOG00000017012 0.06 0.04 4.7e-03 0 0.01 0.02 0.02 1.9e-01 4.3e-02 1.5e-02 2.1e-02
11 NAcc mRNA stability ENSRNOG00000017012 0.41 0.18 0.0e+00 0.22 0.25 0.24 0.26 1.6e-16 2.4e-18 9.0e-18 2.3e-19
12 OFC gene expression ENSRNOG00000017012 0.19 0.12 7.1e-03 0.02 0.06 0.11 0.07 1.2e-01 1.5e-02 1.5e-03 7.9e-03
13 OFC mRNA stability ENSRNOG00000017012 0.26 0.15 2.3e-03 0.08 0.01 0.09 0.06 5.0e-03 1.7e-01 4.0e-03 1.8e-02
14 PL gene expression ENSRNOG00000017012 0.13 0.07 3.4e-06 0.02 0.07 0.07 0.07 1.7e-02 6.2e-06 5.9e-06 9.5e-06
15 PL mRNA stability ENSRNOG00000017012 0.25 0.1 0.0e+00 0.25 0.27 0.27 0.27 7.9e-19 2.8e-20 1.3e-20 1.8e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail2.78.715.3-3.0-3.03.0-3.72.63.0-3.6-1.8-3.01.2-3.7-1.0-3.22.5-3.9
BMI without tail7.014.625.3-4.2-3.94.0-4.83.64.0-4.7-2.1-3.61.4-4.8-1.5-4.13.2-5.0
Body weight1.87.815.3-2.8-2.92.7-3.43.32.7-3.5-1.6-2.10.6-3.3-1.9-3.31.8-3.9
Epididymis fat weight0.92.24.0-2.0-0.72.0-1.71.92.0-1.30.2-0.91.0-1.5-0.1-1.31.8-1.7
Glucose0.30.51.6-0.30.80.20.40.90.20.51.11.30.80.6-0.6-0.30.30.4
Heart weight0.30.41.6-0.20.70.20.30.80.20.50.91.3-1.00.6-0.6-0.3-0.00.4
Left kidney weight2.16.113.4-2.2-2.92.1-2.93.12.1-3.3-1.5-1.41.1-2.9-2.1-2.81.0-3.7
Right kidney weight2.57.014.9-2.3-3.22.2-3.13.12.2-3.5-1.7-1.51.5-3.1-2.3-3.21.1-3.9
Tail length1.64.88.9-2.3-2.22.3-2.63.02.2-2.7-0.8-0.90.0-2.5-2.0-2.91.3-3.0
Length with tail0.30.92.9-0.6-0.90.6-0.91.70.6-1.1-0.40.2-0.0-0.8-1.5-1.4-0.1-1.3
Length without tail0.91.93.11.81.0-1.81.7-0.9-1.81.50.41.4-0.61.6-0.21.1-1.71.4
Liver weight, left0.40.61.3-0.9-0.31.1-0.90.61.1-0.7-0.0-0.90.3-1.00.0-0.41.1-0.9
Liver weight, right1.22.05.8-1.1-1.31.1-1.6-0.11.1-1.4-1.2-2.42.2-1.80.9-0.31.3-1.5
Parametrial fat weight1.93.87.5-2.3-1.42.4-2.22.72.3-2.1-0.0-0.61.3-2.0-1.2-2.01.7-2.6
Retroperitoneal fat weight0.93.17.4-2.60.62.7-1.32.42.7-0.41.8-0.12.0-0.91.0-0.62.7-1.1
Intraocular pressure0.40.62.9-0.4-0.50.8-0.70.40.8-0.7-0.3-0.8-1.7-0.9-0.3-0.60.5-0.7
Extensor digitorum longus weight2.610.425.1-1.1-5.00.9-3.61.90.9-4.6-4.2-2.70.0-3.9-3.6-4.3-0.5-4.3
Soleus weight1.13.28.6-1.3-2.01.2-1.82.91.2-2.2-0.80.2-0.4-1.6-2.4-2.70.1-2.4
Tibialis anterior weight3.913.530.7-2.6-4.62.5-4.23.82.5-4.9-3.0-1.8-0.7-4.2-4.5-5.50.8-4.9
Tibia length0.10.31.3-0.10.60.10.31.00.10.40.81.10.80.6-0.50.1-0.10.2
Number of licking bursts5.56.511.03.11.7-3.33.2-2.9-3.32.60.21.5-1.02.90.82.8-2.73.1
Food consumed during 24 hour testing period1.01.22.9-0.5-1.60.4-1.21.00.4-1.5-1.2-0.60.1-1.2-1.7-1.5-0.1-1.4
Times rat made contact with spout1.41.65.30.7-2.0-0.7-0.70.1-0.7-1.5-2.3-0.8-0.9-0.9-2.3-1.1-1.3-1.0
Mean time between licks in bursts0.10.21.0-0.0-0.2-0.1-0.2-0.9-0.2-0.1-0.7-1.0-0.4-0.30.30.50.10.2
Mean num. licks in bursts5.26.310.7-2.3-2.72.5-3.12.82.5-3.2-1.4-1.60.3-3.0-2.3-3.21.6-3.3
Std. dev. time between licks in bursts0.40.51.9-0.9-0.50.7-0.9-0.30.7-0.6-0.6-1.40.2-1.00.50.11.0-0.5
Water consumed over 24 hours2.42.87.02.6-0.4-2.51.6-1.8-2.50.6-1.60.1-1.31.1-0.91.2-2.71.1
Indifference point 0 sec1.01.64.0-1.70.52.0-0.91.92.0-0.31.30.40.9-0.40.2-1.21.8-0.8
Indifference point AUC0.50.61.8-0.5-0.70.5-0.61.10.5-0.8-0.40.20.8-0.4-1.3-1.30.1-0.8
Indifference point function ln k0.20.21.1-0.5-0.40.6-0.50.50.6-0.50.1-0.2-1.0-0.5-0.3-0.40.3-0.5
Indifference point function log k0.20.21.1-0.5-0.40.6-0.50.50.6-0.50.1-0.2-1.0-0.5-0.3-0.40.3-0.5
Delay discounting total patch changes 0 sec1.21.94.8-2.00.52.2-1.02.02.2-0.41.40.31.1-0.50.3-1.22.0-0.9
Delay discounting total patch changes 12 sec0.40.51.0-0.7-0.30.9-0.70.70.9-0.6-0.2-0.51.0-0.5-0.0-0.90.9-0.7
Delay discounting total patch changes 18 sec0.10.20.8-0.10.50.10.30.40.10.40.50.90.30.6-0.4-0.40.10.3
Delay discounting total patch changes 24 sec0.81.13.2-1.4-0.11.4-0.81.81.4-0.60.50.21.0-0.5-0.4-1.31.2-1.0
Delay discounting total patch changes 6 sec1.32.05.9-0.91.91.10.61.81.11.22.42.21.91.20.3-0.41.10.6
Delay discounting time to switch 0 sec1.52.37.81.70.6-1.71.4-2.8-1.71.2-0.6-0.9-0.60.92.02.1-0.91.7
Delay discounting water rate 0 sec0.20.40.8-0.7-0.40.7-0.70.90.7-0.60.0-0.2-0.2-0.7-0.6-0.50.4-0.8
Delay discounting water rate 12 sec1.21.96.1-1.7-0.21.9-1.32.51.8-0.91.10.60.8-0.9-0.9-1.31.4-1.5
Delay discounting water rate 18 sec0.60.81.9-1.30.21.4-0.81.31.4-0.41.00.10.0-0.60.2-0.41.3-0.7
Delay discounting water rate 24 sec0.20.31.3-0.4-0.50.2-0.51.10.2-0.60.20.6-0.0-0.4-1.1-0.6-0.2-0.7
Delay discounting water rate 6 sec0.20.42.0-0.20.50.00.21.00.00.30.91.40.50.5-0.9-0.1-0.20.0
Locomotor activity0.30.41.8-0.7-0.10.8-0.60.10.8-0.30.0-0.71.3-0.50.6-0.20.9-0.5
Locomotor testing distance0.40.71.7-1.1-0.21.3-0.90.91.3-0.60.2-0.50.6-0.70.1-0.91.1-0.9
Locomotor testing rearing0.50.82.6-1.10.31.3-0.70.41.2-0.10.6-0.71.6-0.51.0-0.21.5-0.4
Light reinforcement 10.40.72.1-1.11.01.1-0.2-0.11.10.51.1-0.00.50.01.10.11.40.5
Light reinforcement 20.50.72.0-1.30.51.3-0.60.31.20.00.9-0.20.4-0.31.1-0.11.4-0.1
Reaction time number correct0.40.62.00.11.0-0.10.7-0.8-0.10.90.70.00.80.61.41.30.30.8
Reaction time mean minus median0.00.10.3-0.2-0.30.0-0.20.30.0-0.3-0.10.00.5-0.1-0.2-0.1-0.1-0.4
Reaction time mean minus median AUC0.30.42.2-0.60.70.40.10.40.40.41.00.41.50.30.80.50.60.0
Reaction time num false alarms1.31.84.22.10.3-1.91.5-1.2-1.91.0-0.30.9-1.11.4-0.20.9-1.81.3
Reaction time num false alarms AUC0.81.12.71.60.2-1.51.1-1.2-1.50.7-0.40.4-1.01.00.20.8-1.31.1
Reaction time trials correct on left0.40.62.00.11.0-0.10.7-0.8-0.10.90.70.00.80.61.41.30.30.8
Reaction time trials on left0.40.62.10.11.0-0.00.7-0.8-0.00.90.8-0.00.80.61.51.30.40.8
Reaction time mean0.40.61.2-1.1-0.50.8-0.80.90.8-0.70.1-0.51.1-0.70.3-0.50.9-0.9
Reaction time mean AUC0.30.40.9-0.9-0.30.7-0.70.50.7-0.50.2-0.60.7-0.60.6-0.20.8-0.7
Median of all reaction times0.50.71.3-1.1-0.50.9-1.00.80.9-0.70.1-0.70.9-0.80.5-0.51.0-1.0
Reaction time omissions0.40.63.2-0.20.20.2-0.1-0.80.20.20.1-1.21.1-0.21.81.10.70.0
Reaction time false alarm rate0.81.12.71.6-0.5-1.50.7-0.9-1.50.2-0.90.4-1.60.6-0.70.1-1.70.6
Reaction time premature initiation rate0.91.33.30.4-1.8-0.0-0.80.3-0.0-1.5-1.6-0.8-1.1-1.1-1.7-1.4-0.7-1.2
Reaction time premature initiations0.30.51.50.6-1.1-0.2-0.2-0.3-0.2-0.8-1.2-0.7-0.9-0.6-0.8-0.5-0.6-0.5
Std. dev. reaction times0.30.41.4-0.9-0.20.7-0.51.00.7-0.50.3-0.11.2-0.40.0-0.40.6-0.8
Reaction time trials completed0.40.62.10.11.0-0.00.7-0.8-0.00.90.8-0.00.80.61.51.30.40.8
Reaction time trials AUC0.30.51.70.00.90.00.6-0.60.00.80.7-0.00.70.51.31.10.40.7
Social response proportion0.60.61.8-0.80.90.9-0.10.40.90.51.20.01.00.11.30.31.30.1
Social responses0.40.52.3-0.31.00.20.3-0.70.20.80.8-0.30.70.31.51.10.80.6
Social time0.81.12.60.61.6-0.51.2-0.6-0.51.51.31.00.71.30.91.2-0.01.3
Conditioned locomotion0.40.52.00.7-0.1-0.90.4-1.4-0.90.3-0.8-0.8-0.30.10.60.8-0.70.5
Cocaine response after cond. corrected0.30.30.50.70.4-0.70.6-0.6-0.70.60.20.4-0.70.60.00.5-0.60.7
Cocaine response after cond. not corrected0.10.10.20.2-0.4-0.2-0.1-0.1-0.2-0.3-0.4-0.2-0.5-0.2-0.3-0.1-0.4-0.2
Cocaine response before conditioning1.51.84.1-0.7-2.00.7-1.51.00.7-2.0-1.5-1.30.6-1.7-1.2-1.40.1-2.0
Saline control response0.20.31.9-0.40.50.50.00.40.50.30.70.21.40.20.60.30.60.0
Condit. Reinf. active minus inactive responses1.51.84.7-2.10.12.1-1.31.22.1-0.60.8-0.61.5-1.00.8-0.82.2-0.9
Condit. Reinf. active-inactive response ratio1.21.33.5-1.50.71.6-0.60.81.60.11.2-0.11.9-0.31.3-0.11.8-0.3
Condit. Reinf. active responses0.91.33.1-1.8-0.21.7-1.20.91.7-0.70.3-0.71.3-1.00.6-0.61.7-0.9
Condit. Reinf. inactive responses0.60.82.0-0.4-1.40.3-1.00.10.2-1.3-1.3-1.1-0.4-1.2-0.8-0.8-0.0-1.1
Condit. Reinf. lever presses1.62.23.8-1.9-0.91.9-1.81.51.9-1.4-0.3-1.21.1-1.7-0.1-1.31.8-1.8
Condit. Reinf. lever reinforcers received0.81.13.0-1.70.11.6-1.00.71.6-0.40.5-0.71.2-0.80.9-0.21.7-0.7
Pavlov. Cond. lever latency0.91.32.21.50.8-1.41.4-1.3-1.31.20.10.7-0.21.30.61.1-1.11.5
Pavlov. Cond. magazine entry latency1.01.23.91.30.4-1.31.0-2.0-1.30.9-0.4-0.4-0.30.60.91.7-0.91.1
Pavlov. Cond. change in total contacts0.71.02.9-1.41.01.2-0.21.11.20.41.70.61.20.10.80.21.4-0.1
Pavlov. Cond. index score0.10.10.3-0.30.10.3-0.2-0.10.20.00.2-0.40.4-0.20.50.50.4-0.1
Pavlov. Cond. latency score0.10.10.3-0.2-0.10.1-0.2-0.20.1-0.1-0.0-0.50.4-0.30.30.40.3-0.2
Pavlov. Cond. lever contacts1.21.73.1-1.7-0.91.6-1.61.31.6-1.4-0.2-1.20.7-1.6-0.3-1.11.4-1.8
Pavlov. Cond. magazine entry number1.21.53.8-0.9-1.41.0-1.41.51.0-1.6-0.8-0.5-0.5-1.3-1.5-1.90.5-1.5
Pavlov. Cond. intertrial magazine entries2.53.35.3-2.0-1.82.0-2.31.52.0-2.2-0.9-1.60.8-2.2-0.5-2.01.7-2.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.10.20.1-0.0-0.40.10.20.2-0.50.4-0.10.80.70.30.0
Pavlov. Cond. response bias0.30.40.8-0.9-0.10.8-0.70.30.8-0.40.2-0.70.5-0.70.5-0.00.9-0.7
Conditioned reinforcement - actives0.50.52.5-0.70.40.30.01.20.30.20.71.60.50.2-1.40.40.00.1
Conditioned reinforcement - inactives0.81.03.00.30.9-0.91.0-0.3-0.91.10.61.70.61.2-0.81.4-0.81.1
Conditioned locomotion0.20.20.7-0.10.5-0.40.3-0.1-0.40.50.40.70.10.40.30.9-0.20.5
Intermittent access intake day 1-15 change1.81.84.12.00.2-2.01.3-1.5-2.00.9-0.70.7-0.71.2-0.41.3-1.81.2
Intermittent access intake escalation1.51.43.21.80.2-1.81.2-1.3-1.80.8-0.60.8-0.61.1-0.51.2-1.61.1
Intermittent access intake escalation 21.81.84.52.10.1-2.01.4-1.5-1.90.8-0.70.7-0.81.2-0.31.3-1.91.2
Intermitt. access day 1 inactive lever presses0.30.31.00.40.2-0.60.5-0.3-0.60.40.01.00.40.5-0.70.6-0.70.5
Intermitt. access day 15 inactive lever presses0.40.41.2-0.1-1.1-0.2-0.5-0.1-0.2-0.8-1.1-0.30.5-0.6-1.0-0.3-0.5-0.7
Intermitt. access escalation Index0.50.51.0-0.5-0.80.6-1.00.40.6-0.9-0.5-0.80.0-0.9-0.2-1.00.5-0.9
Intermittent access day 1 total infusions1.82.05.4-2.3-0.21.9-1.42.11.9-0.90.7-0.31.6-1.1-0.0-1.01.8-1.3
Intermittent access day 15 total infusions0.20.20.8-0.60.20.3-0.20.80.30.00.40.40.90.0-0.20.10.4-0.1
Intermittent access terminal intake (last 3 days)0.30.31.8-0.70.20.4-0.31.20.4-0.00.50.41.3-0.0-0.10.10.5-0.2
Intermittent access total infusions1.01.13.4-1.8-0.11.3-1.01.81.3-0.60.60.11.3-0.7-0.4-0.61.3-0.9
Intermittent access day 1 locomotion1.91.95.8-2.4-0.11.9-1.41.91.9-0.80.8-0.21.5-1.00.1-0.71.9-1.2
Intermittent access day 15 total locomotion1.81.96.6-0.62.00.20.90.60.21.62.21.82.61.30.91.50.70.9
Intermittent access total locomotion1.72.05.0-2.20.61.7-1.02.01.8-0.21.50.12.2-0.50.6-0.32.1-0.8
Intermittent access standard deviation0.20.21.20.2-0.4-0.60.00.1-0.5-0.2-0.60.4-0.10.1-1.10.1-0.70.1
Cocaine induced anxiety0.00.00.2-0.10.2-0.10.1-0.4-0.20.20.0-0.3-0.20.10.30.10.20.1
Post-drug Anxiety0.30.41.4-0.11.10.00.50.2-0.00.81.01.20.30.7-0.20.20.20.6
Baseline Anxiety0.30.31.8-0.2-0.00.2-0.10.80.3-0.20.41.30.00.0-1.3-0.3-0.3-0.1
Lifetime Intake1.61.84.9-2.2-0.41.7-1.52.11.7-1.00.5-0.11.3-1.1-0.5-0.91.6-1.4
Incentive Sensitization - Responses0.20.21.0-0.80.20.5-0.20.30.5-0.00.4-0.5-0.1-0.21.00.00.7-0.1
Incentive Sensitization - Breakpoint0.30.30.9-0.90.20.6-0.20.40.6-0.00.5-0.4-0.0-0.21.0-0.00.8-0.2
Progressive ratio test 1 active lever presses0.90.92.8-1.7-0.11.2-1.01.21.2-0.50.6-0.41.2-0.60.5-0.31.4-0.7
Progressive ratio test 1 breakpoint0.90.92.6-1.6-0.01.1-0.91.31.1-0.50.6-0.41.4-0.60.5-0.31.4-0.7
Progressive ratio test 1 inactive lever presses0.60.62.1-1.3-0.40.7-0.90.80.7-0.7-0.1-0.41.4-0.7-0.3-0.50.9-0.9
Progressive ratio test 2 active lever presses0.70.82.6-1.60.31.1-0.71.31.1-0.20.80.01.0-0.40.4-0.11.3-0.5
Progressive ratio test 2 breakpoint0.70.82.7-1.60.31.1-0.71.31.1-0.20.9-0.01.0-0.40.6-0.11.4-0.5
Progressive ratio test 2 inactive lever presses0.60.72.6-1.30.50.9-0.41.10.90.10.90.11.6-0.20.70.21.2-0.3
Total sessions with >9 infusions2.93.25.8-2.2-1.91.6-2.22.21.6-2.2-0.9-0.60.8-2.0-2.1-1.60.9-2.4
Short access day 1 total inactive lever presses0.20.30.7-0.80.40.4-0.20.70.40.20.60.70.80.1-0.40.30.50.0
Short access day 10 total inactive lever presses1.01.22.11.00.9-1.31.2-1.0-1.31.20.31.50.51.3-0.31.2-1.11.2
Short access day 1 total infusions1.51.64.6-1.9-0.31.4-1.22.21.4-0.90.50.41.7-0.9-1.0-0.41.2-1.3
Short access day 10 total infusions1.11.22.8-1.7-1.01.1-1.41.31.1-1.3-0.4-0.50.9-1.2-0.9-0.80.8-1.4
Short access total infusions2.52.86.6-2.6-0.72.1-1.92.52.1-1.40.4-0.21.5-1.5-0.9-1.31.8-1.9
Short access day 1 locomotion0.40.41.5-0.80.10.4-0.31.20.5-0.20.40.71.2-0.1-0.70.30.4-0.5
Short access day 10 total locomotion2.22.44.8-2.2-1.21.8-2.01.51.8-1.6-0.2-1.40.9-1.7-0.1-1.51.8-1.7
Short access total locomotion3.43.58.3-2.8-0.12.5-1.82.92.5-1.01.30.02.4-1.3-0.3-0.92.4-1.6
Compulsive drug intake1.01.02.2-1.0-0.11.4-0.91.01.4-0.60.4-1.1-0.3-0.91.0-1.21.5-0.8
One hour access (0.3 mA shock)2.22.66.2-2.5-0.82.1-1.92.02.1-1.50.1-1.10.1-1.70.0-1.62.0-1.6
One hour access (shock baseline)0.20.20.8-0.20.6-0.10.30.2-0.10.50.60.90.50.5-0.10.7-0.00.5
Number of responses in last shaping day0.50.51.1-1.1-0.60.7-0.90.90.7-0.8-0.3-0.30.6-0.8-0.4-0.50.6-0.8
Context. condit. distance diff. score0.30.41.8-0.00.70.10.4-0.50.10.60.9-0.10.30.31.31.00.40.5
Locomotion velocity, session 10.40.42.20.7-0.1-0.70.4-0.1-0.70.1-0.10.6-1.50.4-0.9-0.3-0.80.4
Locomotion distance, session 10.81.11.8-1.3-0.61.3-1.31.21.3-1.00.1-0.5-0.3-1.1-0.5-1.31.2-1.0
Locomotion velocity, session 20.50.62.31.00.4-0.80.7-0.4-0.80.60.11.0-1.50.8-0.7-0.0-1.00.9
Locomotion distance, session 21.11.63.9-1.0-1.40.9-1.41.30.9-1.6-0.9-0.6-1.1-1.4-1.8-2.00.3-1.4
Locomotion velocity, session 30.20.20.6-0.4-0.40.5-0.50.30.5-0.5-0.2-0.20.1-0.6-0.5-0.80.2-0.5
Locomotion distance, session 30.50.62.30.7-1.2-0.6-0.2-0.6-0.6-0.8-1.5-0.9-0.5-0.6-0.8-0.3-0.8-0.5
Stereotopy head waving bouts, day 30.40.51.4-0.11.20.00.6-0.00.01.01.20.70.50.80.80.60.40.7
Stereotopy head waving duration, day 30.40.51.6-0.51.10.40.30.20.40.81.30.70.50.50.90.40.70.6
Locomotion velocity, session 71.11.23.20.0-1.80.2-1.1-0.50.2-1.5-1.6-1.6-1.0-1.4-0.7-0.7-0.3-1.1
Locomotion distance, session 70.70.95.60.9-0.9-0.90.1-1.0-0.9-0.4-1.3-0.7-2.4-0.2-0.50.1-1.2-0.0
Stereotopy head waving bouts, day 70.30.30.7-0.90.10.8-0.60.80.8-0.20.30.20.7-0.4-0.3-0.60.7-0.4
Stereotopy head waving duration, day 71.51.82.9-1.6-1.01.6-1.71.31.6-1.4-0.4-1.01.1-1.6-0.5-1.41.4-1.6
Locomotion velocity, session 80.00.00.3-0.00.10.00.10.30.00.10.10.4-0.10.1-0.5-0.3-0.10.3
Locomotion distance, session 80.10.20.6-0.5-0.40.5-0.50.30.5-0.50.1-0.4-0.8-0.6-0.1-0.40.3-0.5
Degree of sensitization distance0.40.41.7-0.41.00.30.30.60.30.71.31.1-0.50.60.40.10.40.5
Degree of sensitization stereotypy0.91.01.8-1.0-1.01.0-1.20.91.0-1.2-0.5-0.60.1-1.2-1.0-1.30.5-1.1
Condit. Reinf. active minus inactive responses0.30.31.3-0.30.50.40.00.40.40.30.7-0.11.10.11.10.50.8-0.0
Condit. Reinf. active-inactive response ratio0.60.73.6-0.50.00.7-0.50.30.7-0.20.3-0.81.9-0.41.50.51.1-0.5
Condit. Reinf. active responses0.10.10.5-0.00.50.30.20.30.30.40.70.2-0.10.20.50.20.50.2
Condit. Reinf. inactive responses0.30.33.50.10.30.00.20.10.00.20.30.5-1.90.2-0.7-0.4-0.10.3
Incentive salience index mean0.20.20.8-0.0-0.50.2-0.4-0.10.2-0.4-0.4-0.90.8-0.50.70.20.4-0.5
Condit. Reinf. lever presses0.30.41.60.4-0.6-0.3-0.2-1.1-0.3-0.3-1.0-1.30.1-0.50.80.5-0.2-0.2
Time in familiar zone, hab. session 10.90.82.90.61.2-0.51.00.4-0.51.11.21.71.01.3-0.10.3-0.40.9
Time in novel zone, hab. session 10.90.82.8-0.5-1.10.7-1.0-0.20.7-1.1-1.1-1.7-1.0-1.30.1-0.40.5-0.9
Total zone transitions, hab. session 11.62.36.3-1.3-1.21.4-1.52.31.4-1.6-0.30.1-0.9-1.3-2.2-2.50.6-1.7
Total locomotion distance, hab. session 13.85.512.4-2.5-1.92.6-2.73.32.6-2.6-0.3-0.40.2-2.3-2.3-3.51.7-2.8
Locomotion velocity, hab. session 13.55.09.9-2.7-1.62.7-2.73.12.7-2.4-0.1-0.50.6-2.3-1.7-3.12.0-2.6
Time in familiar zone, hab. session 20.30.31.1-0.4-0.40.3-0.50.80.3-0.5-0.30.1-0.1-0.3-1.1-1.00.1-0.5
Time in novel zone, hab. session 20.10.10.6-0.20.30.3-0.1-0.10.30.10.4-0.20.7-0.10.80.40.50.1
Total zone transitions, hab. session 21.62.14.8-1.6-1.01.7-1.62.21.7-1.50.0-0.20.2-1.4-1.4-2.11.2-1.8
Total locomotion distance, hab. session 22.02.77.1-1.6-1.31.6-1.82.51.6-1.8-0.20.00.1-1.5-2.0-2.71.0-1.9
Locomotion velocity, hab. session 22.43.27.8-1.7-1.61.7-2.02.61.7-2.1-0.5-0.30.2-1.8-2.1-2.81.0-2.2
Novel to familiar place preference ratio0.70.81.41.10.8-1.01.2-0.4-1.01.00.51.0-0.51.10.00.7-0.91.0
Novelty place preference1.11.11.91.40.8-1.21.4-0.5-1.21.10.41.2-0.71.3-0.20.7-1.31.1
Time in novel zone, NPP test0.70.81.41.00.9-0.91.2-0.3-0.91.10.61.2-0.61.2-0.10.6-0.91.0
Total zone transitions, NPP test1.01.54.0-1.2-1.11.2-1.41.51.2-1.4-0.3-0.2-0.5-1.3-1.5-2.00.7-1.4
Total locomotion distance, NPP test1.11.54.8-1.0-1.11.0-1.31.61.0-1.4-0.40.2-1.0-1.1-1.9-2.20.3-1.2
Locomotion velocity, NPP test0.81.24.0-0.8-1.00.8-1.11.40.8-1.2-0.40.2-0.9-0.9-1.8-2.00.1-1.1
Pavlov. Cond. lever latency1.92.510.30.91.9-0.91.90.9-0.91.82.03.2-0.62.2-0.90.4-1.11.6
Pavlov. Cond. magazine entry latency3.74.713.8-1.8-2.51.8-2.80.01.8-2.7-2.1-3.70.5-3.10.5-1.31.8-2.5
Pavlov. Cond. change in total contacts2.42.510.60.1-2.40.0-1.6-1.50.0-1.9-2.7-3.3-0.1-2.10.4-0.30.1-1.4
Pavlov. Cond. index score2.93.714.5-1.2-2.31.2-2.3-0.81.2-2.2-2.2-3.80.9-2.71.1-0.51.4-2.0
Pavlov. Cond. latency score2.63.312.5-1.2-2.11.3-2.2-0.61.3-2.1-2.0-3.51.0-2.51.1-0.61.4-1.9
Pavlov. Cond. lever contacts2.93.413.7-1.0-2.41.0-2.2-0.91.0-2.2-2.4-3.70.5-2.60.8-0.61.1-1.9
Pavlov. Cond. magazine entry number2.43.012.50.82.3-0.82.00.9-0.82.12.33.50.02.5-0.70.6-0.91.8
Pavlov. Cond. intertrial magazine entries1.31.65.00.22.0-0.11.30.5-0.11.72.12.2-0.11.70.40.8-0.01.3
Pavlov. Cond. lever-magazine prob. diff.3.54.416.2-1.4-2.51.4-2.5-0.71.4-2.4-2.4-4.01.0-2.91.1-0.71.6-2.2
Pavlov. Cond. response bias2.83.414.7-0.6-2.50.6-2.1-1.30.6-2.2-2.7-3.8-0.0-2.60.7-0.50.8-1.8
Bone: apparent density0.61.02.6-1.0-0.90.9-1.11.60.9-1.2-0.4-0.3-0.2-1.0-1.1-1.50.5-1.3
Bone surface0.71.22.3-0.7-1.50.5-1.30.70.5-1.5-1.3-0.9-0.8-1.3-1.4-1.50.1-1.5
Bone volume1.11.83.7-1.0-1.61.0-1.61.41.0-1.8-1.1-0.7-0.7-1.5-1.7-1.90.3-1.8
Bone: connectivity density0.50.71.2-0.9-0.90.8-1.10.90.8-1.1-0.6-0.90.4-1.0-0.5-0.90.7-1.1
Bone: cortical apparent density0.70.91.31.10.7-1.11.1-1.0-1.11.00.40.90.41.10.61.1-1.01.1
Bone: cortical area2.13.16.4-1.3-2.21.3-2.11.71.3-2.4-1.3-0.9-0.9-2.0-2.1-2.50.3-2.4
Bone: cortical porosity1.11.22.4-1.4-0.71.5-1.31.01.5-1.1-0.2-1.10.3-1.30.1-0.81.5-1.2
Bone: cortical porosity0.90.92.4-1.4-0.21.5-1.00.71.5-0.60.2-1.00.5-1.00.7-0.31.6-0.8
Bone: cortical thickness0.91.44.9-0.4-1.20.5-0.91.50.5-1.2-0.50.5-1.7-0.8-2.2-2.0-0.5-1.3
Bone: cortical thickness0.70.93.40.70.0-0.60.61.2-0.60.10.31.8-0.90.7-1.9-0.8-1.2-0.0
Bone: cortical tissue density0.70.91.31.10.7-1.11.2-1.0-1.11.00.50.90.41.10.71.1-1.01.1
Bone: elastic displacement0.70.72.30.31.3-0.21.00.4-0.21.21.21.5-0.31.20.10.5-0.21.1
Bone: elastic work0.20.20.7-0.2-0.30.2-0.20.80.2-0.4-0.10.4-0.8-0.2-0.8-0.7-0.2-0.4
Bone: endosteal estimation1.43.15.9-1.4-2.41.2-2.20.81.2-2.4-1.9-2.20.9-2.3-0.8-1.60.9-2.4
Bone: endosteal perimeter0.91.84.6-0.4-2.10.2-1.5-0.20.2-1.9-2.1-1.9-0.5-1.7-1.0-1.1-0.2-1.6
Bone: final force3.66.011.7-1.9-3.11.9-2.92.41.9-3.3-1.8-1.5-0.8-2.9-2.7-3.40.7-3.3
Bone: final moment3.15.19.9-2.0-2.62.0-2.82.42.0-3.0-1.3-1.3-0.6-2.6-2.3-3.10.9-3.0
Bone: marrow area1.32.85.3-1.3-2.31.1-2.10.71.1-2.3-1.8-2.11.0-2.2-0.7-1.50.8-2.3
Bone: maximum diameter1.52.85.4-1.5-2.21.4-2.21.21.4-2.3-1.4-1.50.5-2.1-1.3-2.00.7-2.3
Bone: maximum force2.84.89.5-1.6-2.81.5-2.62.21.5-3.0-1.7-1.3-0.8-2.5-2.5-3.10.4-3.0
Bone: maximum moment2.33.97.7-1.7-2.41.6-2.32.21.6-2.6-1.3-1.1-0.5-2.2-2.1-2.80.6-2.7
Bone: minimum diameter1.32.55.1-1.1-2.21.0-1.90.71.0-2.2-1.7-1.7-0.6-2.1-1.1-1.80.4-2.1
Bone: periosteal estimation2.34.69.0-1.7-2.91.5-2.71.51.5-3.0-2.0-2.00.0-2.7-1.8-2.60.7-3.0
Bone: periosteal perimeter1.32.24.0-1.4-1.91.3-1.90.71.3-2.0-1.3-1.7-0.2-2.0-0.7-1.60.7-2.0
Bone: post-yield work3.44.78.1-2.8-1.42.7-2.51.92.7-2.1-0.2-1.72.8-2.20.3-1.52.6-2.5
Bone: stiffness2.03.27.6-0.8-2.50.7-1.91.70.7-2.4-1.6-0.7-1.2-1.8-2.6-2.8-0.3-2.4
Bone: tissue strength0.20.20.80.4-0.3-0.50.2-0.1-0.5-0.1-0.40.1-0.90.1-0.5-0.0-0.70.0
Bone: trabecular number0.30.51.4-0.5-0.70.5-0.71.20.5-0.8-0.40.1-0.5-0.6-1.2-1.20.1-0.8
Bone: trabecular spacing0.40.62.50.20.30.00.1-1.30.00.4-0.1-1.20.5-0.11.61.40.50.4
Bone: trabecular thickness1.92.39.0-2.0-0.21.9-1.23.01.9-1.01.21.00.1-0.7-1.1-2.11.3-1.4
Bone: trabecular tissue density0.10.10.30.20.0-0.30.1-0.1-0.30.10.10.5-0.60.3-0.4-0.2-0.40.2
Breakpoint value in progressive ratio session1.41.64.2-0.32.00.21.0-0.30.31.72.01.00.91.12.01.30.81.5
Distance traveled before self-admin0.40.41.20.10.0-0.70.5-0.0-0.70.2-0.11.0-1.00.6-1.1-0.0-1.00.3
Distance traveled after self-admin1.41.56.0-0.1-1.7-0.1-0.80.5-0.1-1.4-1.4-0.2-2.0-0.9-2.5-1.5-0.8-1.1
Delta time in closed arm before/after self-admin0.40.41.60.9-0.5-0.60.2-1.2-0.5-0.1-1.0-1.1-0.5-0.20.50.3-0.50.3
Delta time in open arm before/after self-admin1.91.84.2-1.3-1.11.5-1.52.11.5-1.5-0.2-0.30.6-1.3-1.2-1.71.0-1.8
Diff in mean of infusions in LGA sessions0.91.03.5-0.61.60.50.40.50.51.11.91.11.20.81.10.70.90.8
Extinction: sum of active levers before priming0.30.30.60.70.3-0.60.6-0.7-0.60.50.10.2-0.10.50.40.6-0.50.7
Active lever presses in extinction session 60.40.41.4-1.00.80.7-0.00.30.70.41.20.30.70.10.60.20.90.1
Delta distance traveled before/after self-admin1.21.32.3-0.7-1.40.9-1.40.70.8-1.5-1.0-1.3-0.7-1.5-1.1-1.30.6-1.4
Delta ambulatory time before/after self-admin0.91.01.8-0.5-1.30.7-1.10.70.6-1.3-0.9-0.9-0.8-1.3-1.2-1.30.3-1.2
Time in closed arm before self-admin0.50.51.5-1.2-0.40.7-0.91.00.8-0.70.00.2-0.0-0.5-0.8-0.90.5-0.9
Time in closed arm after self-admin0.80.82.40.01.5-0.10.9-0.1-0.11.31.51.40.21.10.40.70.01.1
Time in open arm before self-admin1.51.63.21.41.1-1.21.4-1.8-1.21.40.30.20.11.31.61.7-0.71.7
Time in open arm after self-admin1.21.33.50.1-1.90.2-1.10.40.1-1.6-1.8-1.2-0.4-1.3-1.3-1.2-0.2-1.4
Sum of active levers in priming session hrs 5-60.50.51.7-0.80.30.9-0.50.00.9-0.00.5-0.70.7-0.41.30.11.2-0.1
Time to tail flick, vehicle, before self-admin0.30.30.80.5-0.90.0-0.3-0.1-0.0-0.7-0.9-0.6-0.3-0.5-0.2-0.5-0.4-0.6
Time to tail flick, vehicle, after self-admin0.70.82.50.21.0-0.60.8-1.3-0.61.10.5-0.30.10.71.61.40.11.0
Time to tail flick, test, before self-admin0.50.51.51.1-0.8-0.80.2-0.4-0.8-0.4-1.2-0.3-1.0-0.1-0.8-0.2-1.1-0.1
Time to tail flick, test, after self-admin1.41.55.51.6-0.3-1.70.9-2.3-1.70.5-1.3-0.9-0.30.50.71.2-1.40.7
Delta time to tail flick, vehicle, before/after SA0.30.31.1-0.80.70.4-0.1-0.10.40.40.7-0.40.50.01.10.50.90.3
Delta time to tail flick, test, before/after SA0.20.20.8-0.2-0.1-0.2-0.0-0.9-0.20.0-0.3-0.80.8-0.10.80.50.1-0.0
Ambulatory time before self-admin0.60.72.5-0.10.4-0.90.80.1-0.90.50.31.6-1.00.9-1.10.1-1.10.6
Ambulatory time after self-admin1.51.66.5-0.1-1.6-0.2-0.70.5-0.2-1.4-1.4-0.0-2.4-0.8-2.6-1.5-1.0-1.0
Total heroin consumption0.91.13.9-1.31.40.70.10.10.70.91.50.11.40.52.00.91.40.6
Area under the delay curve0.50.51.30.80.7-0.70.9-0.2-0.80.80.51.1-0.10.8-0.50.5-0.80.8
Delay disc. indifference point, 0s delay0.90.94.01.1-1.1-1.10.1-0.1-1.1-0.6-1.20.4-0.3-0.3-2.0-0.3-1.6-0.4
Delay disc. indifference point, 16s delay3.94.07.91.42.8-1.22.5-1.1-1.32.82.22.30.32.61.42.3-0.72.7
Delay disc. indifference point, 2s delay2.42.66.3-0.5-2.30.8-1.71.50.8-2.2-1.6-0.8-0.5-2.0-2.5-2.2-0.1-2.1
Delay disc. indifference point, 24s delay3.33.26.01.72.0-1.72.3-1.8-1.82.31.21.5-0.62.10.62.0-1.32.5
Delay disc. indifference point, 4s delay0.70.73.20.80.3-0.70.80.6-0.70.40.41.6-0.70.6-1.8-0.2-1.10.4
Delay disc. indifference point, 8s delay0.40.41.30.80.0-0.80.6-0.2-0.90.3-0.10.8-0.50.5-0.8-0.0-1.10.4
Delay discount exponential model param0.40.51.0-0.8-0.70.6-0.90.30.7-0.8-0.5-1.00.2-0.80.4-0.50.8-0.8
Delay discount hyperbolic model param0.30.30.9-0.7-0.40.5-0.70.00.6-0.5-0.3-0.90.2-0.50.8-0.20.8-0.5
Fecal boli incidents, locomotor time 10.40.51.7-0.40.40.20.0-1.10.20.30.3-1.3-0.3-0.31.11.10.80.5
Change in fecal boli incidents, locomotor task1.31.23.7-1.30.91.1-0.11.91.10.31.41.9-0.70.6-0.9-1.40.6-0.1
Time >=10cm from walls, locomotor time 10.40.42.0-0.3-0.8-0.1-0.50.2-0.1-0.7-0.7-0.1-0.7-0.5-1.4-0.6-0.4-0.6
Bouts of movement, locomotor time 11.82.04.10.81.7-1.01.5-2.0-1.01.80.80.40.21.61.91.9-0.31.9
Total resting periods, locomotor time 12.12.35.01.01.8-1.11.7-2.2-1.12.00.90.40.21.61.92.2-0.42.0
Rest time, locomotor task time 11.71.94.21.50.6-2.01.5-2.0-2.01.2-0.40.7-0.81.3-0.41.1-1.91.4
Distance moved, locomotor task time 12.22.45.5-1.5-0.92.1-1.72.42.1-1.40.0-0.51.7-1.30.1-1.61.8-1.8
Vertical activity count, locomotor time 11.71.85.5-0.8-1.51.0-1.52.31.0-1.6-0.80.10.9-1.1-1.4-2.00.4-1.7
Time >=10cm from walls, locomotor time 21.31.34.4-0.5-1.70.2-1.00.90.2-1.6-1.3-0.5-0.8-1.2-2.1-1.2-0.4-1.4
Bouts of movement, locomotor time 21.51.66.5-0.8-1.20.6-1.2-1.10.6-1.1-1.3-2.61.7-1.51.50.21.0-0.9
Total resting periods, locomotor time 21.61.76.4-0.9-1.30.7-1.4-0.80.7-1.3-1.3-2.51.7-1.71.3-0.01.0-1.1
Rest time, locomotor task time 20.10.10.4-0.40.40.10.10.20.10.20.60.60.10.2-0.6-0.00.00.2
Distance moved, locomotor task time 20.50.62.00.9-1.3-0.8-0.30.0-0.8-0.8-1.4-0.00.2-0.3-0.7-0.5-1.1-0.7
Vertical activity count, locomotor time 20.50.62.10.6-0.9-0.7-0.10.8-0.7-0.5-0.80.90.40.3-1.5-0.8-1.1-0.4
Weight adjusted by age1.21.33.8-1.5-0.71.3-1.30.21.3-0.9-0.4-2.00.7-1.21.5-0.41.6-0.9
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.40.10.1-0.1-0.10.10.10.10.20.10.10.2-0.00.10.0
Locomotion in novel chamber1.41.75.4-2.3-0.31.9-1.41.31.9-0.90.6-0.80.4-1.20.4-0.81.9-1.1
Locomotion in novel chamber post-restriction0.91.13.0-1.31.21.4-0.21.01.40.51.70.41.30.30.8-0.01.50.2
Progressive ratio0.60.61.6-0.81.00.8-0.01.10.80.51.31.01.20.30.2-0.31.00.1
Food seeking constrained by brief footshock1.41.72.81.41.4-1.11.7-0.7-1.11.51.21.4-1.41.60.11.5-1.11.6
Seeking ratio, punishment vs. effort0.40.52.70.6-0.8-0.40.1-0.9-0.5-0.4-0.8-1.0-1.7-0.3-0.10.5-0.7-0.1
Run reversals in cocaine runway, females3.33.37.3-0.6-2.70.8-1.91.60.7-2.6-2.0-0.8-0.5-2.0-2.7-2.3-0.4-2.5
Run reversals in cocaine runway, males0.60.60.90.80.5-0.90.9-0.7-0.90.70.10.7-0.50.8-0.10.9-0.90.9
Latency to leave start box in cocaine runway0.60.72.5-0.51.20.80.31.00.80.71.61.00.50.50.60.40.90.4
Latency to leave start box in cocaine runway, F0.20.31.5-0.20.70.40.2-0.10.40.40.6-0.3-0.10.11.20.70.70.3
Latency to leave start box in cocaine runway, M1.00.93.8-0.21.40.40.61.30.40.91.82.00.31.0-0.2-0.10.30.6
Cd content in liver3.64.08.90.33.0-0.12.0-0.7-0.12.62.81.71.72.22.82.60.62.3
Co content in liver1.11.23.70.21.50.11.10.60.11.21.71.9-1.81.4-0.30.4-0.01.1
Cu content in liver0.50.51.9-0.80.21.0-0.31.41.0-0.20.80.7-0.7-0.2-0.6-0.90.7-0.4
Fe content in liver1.31.63.31.21.2-1.21.5-0.5-1.21.40.91.8-1.51.6-0.40.7-1.11.5
K content in liver0.20.20.4-0.5-0.20.6-0.5-0.20.6-0.30.0-0.5-0.1-0.50.5-0.20.6-0.4
Mg content in liver0.70.72.5-0.90.11.0-0.7-0.51.0-0.20.1-1.30.2-0.71.60.41.4-0.2
Mn content in liver0.30.31.00.1-1.0-0.2-0.5-0.7-0.2-0.7-1.0-0.9-0.2-0.7-0.1-0.3-0.3-0.6
Na content in liver3.73.99.7-0.5-3.10.5-2.3-0.10.5-2.8-2.8-2.5-0.5-2.7-1.5-2.2-0.1-2.5
Rb content in liver1.41.86.5-1.32.11.30.61.01.31.32.51.50.31.10.60.41.61.0
Se content in liver0.30.42.30.6-0.6-0.5-0.1-0.6-0.5-0.3-0.8-0.2-1.5-0.2-0.7-0.4-0.7-0.1
Sr content in liver0.60.61.8-0.5-1.00.5-0.80.10.5-1.0-0.6-0.81.3-0.9-0.1-0.70.4-1.1
Zn content in liver2.83.05.5-1.6-1.91.7-2.31.01.7-2.2-1.3-1.9-0.8-2.3-0.9-2.11.3-2.1