Hub : Genes

Ide

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000098836 0.04 0.03 1.5e-03 0.02 0.02 0 0.01 5.2e-03 3.7e-03 1.1e-01 1.7e-02
2 Adipose alternative TSS ENSRNOT00000098836 0.04 0.04 1.3e-03 0.02 0.02 0.01 0.01 4.6e-03 3.3e-03 3.7e-02 1.6e-02
3 Adipose gene expression ENSRNOG00000016833 0.04 0.02 1.7e-04 0.04 0.04 0.03 0.03 7.7e-05 7.6e-05 4.7e-04 1.3e-04
4 Adipose isoform ratio ENSRNOT00000098836 0.03 0.03 3.8e-03 0 0.01 -0 0 1.2e-01 1.2e-02 4.7e-01 9.0e-02
5 Adipose mRNA stability ENSRNOG00000016833 0.17 0.07 0.0e+00 0.2 0.2 0.17 0.19 1.0e-21 1.9e-21 1.9e-18 1.2e-20
6 Brain gene expression ENSRNOG00000016833 0.04 0.03 4.0e-04 0.02 0.03 0.02 0.02 3.3e-03 1.2e-03 4.5e-03 4.9e-03
7 Liver alternative TSS ENSRNOT00000110995 0.03 0.02 6.9e-03 0 0.01 0 0 2.7e-01 3.7e-02 1.6e-01 2.3e-01
8 Liver alternative TSS ENSRNOT00000110995 0.03 0.03 6.1e-03 0 0.01 0 0 2.3e-01 2.7e-02 9.4e-02 2.2e-01
9 Liver gene expression ENSRNOG00000016833 0.12 0.06 7.2e-16 0.13 0.14 0.14 0.14 2.0e-14 1.4e-15 2.1e-15 6.1e-15
10 PL gene expression ENSRNOG00000016833 0.04 0.03 6.1e-03 0.01 0.02 0.01 0.01 4.7e-02 1.7e-02 7.1e-02 8.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
BMI with tail0.10.20.4-0.6-0.6-0.4-0.6-0.5-0.10.20.20.4-0.4
BMI without tail0.10.20.4-0.4-0.4-0.5-0.4-0.6-0.20.50.40.5-0.3
Body weight0.41.85.8-1.3-1.3-0.2-1.5-0.4-2.4-0.5-0.61.1-2.3
Epididymis fat weight0.20.61.30.50.50.90.40.8-0.9-1.1-1.1-0.5-0.2
Glucose0.10.20.5-0.4-0.4-0.2-0.5-0.2-0.60.10.10.3-0.7
Heart weight1.62.33.7-1.5-1.5-1.9-1.4-1.70.51.91.91.7-0.5
Left kidney weight0.30.82.1-1.0-1.0-0.1-1.0-0.0-1.4-0.5-0.60.8-1.3
Right kidney weight0.10.40.6-0.8-0.8-0.1-0.8-0.0-0.8-0.4-0.40.6-0.7
Tail length0.30.84.00.10.10.5-0.10.3-2.0-0.8-0.90.0-1.3
Length with tail0.51.98.3-0.8-0.80.3-1.10.2-2.9-0.9-1.10.8-2.4
Length without tail0.81.76.0-0.2-0.21.1-0.51.0-2.5-1.7-1.8-0.1-1.7
Liver weight, left1.11.76.7-0.7-0.70.6-0.90.4-2.6-1.4-1.50.3-2.0
Liver weight, right0.81.32.50.60.61.40.31.2-1.6-1.6-1.6-0.8-0.9
Parametrial fat weight0.10.31.0-0.4-0.40.1-0.50.1-0.9-0.3-0.30.3-1.0
Retroperitoneal fat weight0.00.10.6-0.2-0.20.1-0.4-0.1-0.7-0.2-0.20.1-0.7
Intraocular pressure0.60.81.2-1.0-1.0-0.9-1.1-0.9-0.30.70.71.1-0.8
Extensor digitorum longus weight0.83.05.31.31.32.20.91.8-1.9-2.3-2.3-1.7-0.8
Soleus weight1.02.84.9-1.6-1.6-1.6-1.8-1.8-1.41.51.41.7-2.2
Tibialis anterior weight1.65.58.62.12.22.91.72.6-2.1-2.9-2.9-2.4-0.5
Tibia length0.20.61.0-1.0-1.0-0.8-0.9-0.7-0.50.50.51.0-0.8
Number of licking bursts2.12.54.91.81.71.31.91.51.6-0.9-0.8-1.62.2
Food consumed during 24 hour testing period0.00.00.1-0.3-0.3-0.3-0.2-0.2-0.00.10.00.30.1
Times rat made contact with spout1.31.52.31.51.51.41.41.4-0.1-1.1-1.0-1.30.7
Mean time between licks in bursts0.60.91.9-0.5-0.5-1.1-0.3-0.91.31.31.40.60.7
Mean num. licks in bursts0.60.82.7-0.6-0.6-0.3-0.9-0.5-1.50.20.10.7-1.6
Std. dev. time between licks in bursts0.70.83.70.20.2-0.60.3-0.31.91.01.1-0.01.3
Water consumed over 24 hours3.03.65.22.32.32.12.22.0-0.2-1.8-1.8-2.11.2
Indifference point 0 sec0.50.81.2-1.1-1.1-1.1-0.9-0.90.20.80.81.1-0.2
Indifference point AUC0.50.61.11.01.10.71.00.80.7-0.3-0.2-1.00.8
Indifference point function ln k0.81.12.0-1.3-1.3-0.7-1.2-0.8-1.40.1-0.11.1-1.3
Indifference point function log k0.81.12.0-1.3-1.3-0.7-1.2-0.8-1.40.1-0.11.1-1.3
Delay discounting total patch changes 0 sec0.60.91.4-1.2-1.2-1.2-1.0-1.00.20.90.91.2-0.4
Delay discounting total patch changes 12 sec0.40.52.50.40.4-0.10.50.11.60.50.7-0.21.2
Delay discounting total patch changes 18 sec0.10.10.50.20.2-0.00.30.20.70.20.2-0.10.5
Delay discounting total patch changes 24 sec0.10.10.10.30.30.30.30.3-0.1-0.2-0.2-0.30.1
Delay discounting total patch changes 6 sec0.40.61.3-0.4-0.4-0.9-0.2-0.51.21.01.00.60.6
Delay discounting time to switch 0 sec0.50.82.40.80.70.51.00.71.4-0.3-0.2-0.71.5
Delay discounting water rate 0 sec0.10.20.9-0.3-0.3-0.2-0.4-0.3-0.90.10.00.3-0.8
Delay discounting water rate 12 sec0.50.71.1-1.1-1.1-0.7-1.0-0.9-0.90.30.10.9-1.0
Delay discounting water rate 18 sec0.40.52.1-0.6-0.6-0.1-0.7-0.5-1.5-0.4-0.50.4-1.2
Delay discounting water rate 24 sec0.50.73.0-0.4-0.40.4-0.50.3-1.7-0.9-1.00.2-1.2
Delay discounting water rate 6 sec0.40.60.8-0.9-0.9-0.9-0.8-0.8-0.10.80.80.9-0.6
Locomotor activity0.20.31.20.30.3-0.10.60.10.90.10.1-0.31.1
Locomotor testing distance0.20.31.40.20.2-0.30.5-0.11.00.40.4-0.11.2
Locomotor testing rearing0.20.40.70.50.50.70.50.7-0.6-0.8-0.9-0.60.1
Light reinforcement 10.20.30.4-0.7-0.7-0.6-0.7-0.70.10.60.60.6-0.4
Light reinforcement 21.11.55.91.01.0-0.11.1-0.12.40.91.1-0.71.9
Reaction time number correct0.30.41.4-0.5-0.50.1-0.60.1-1.2-0.5-0.50.4-0.9
Reaction time mean minus median1.82.43.8-1.8-1.8-1.9-1.6-1.6-0.21.51.32.0-0.8
Reaction time mean minus median AUC1.51.93.1-1.5-1.5-1.7-1.3-1.40.51.51.41.7-0.1
Reaction time num false alarms0.81.12.20.60.71.30.51.1-1.3-1.5-1.5-0.9-0.5
Reaction time num false alarms AUC0.60.91.70.60.61.10.51.0-1.0-1.3-1.3-0.8-0.3
Reaction time trials correct on left0.30.41.4-0.5-0.50.1-0.60.1-1.2-0.5-0.50.4-0.9
Reaction time trials on left0.30.41.4-0.5-0.50.1-0.50.1-1.2-0.5-0.60.4-0.9
Reaction time mean0.50.62.20.10.1-0.70.3-0.71.51.01.0-0.01.1
Reaction time mean AUC0.60.83.00.10.1-0.70.4-0.71.71.11.1-0.01.3
Median of all reaction times0.70.93.40.70.6-0.30.8-0.41.90.80.9-0.61.5
Reaction time omissions0.10.10.3-0.4-0.4-0.4-0.2-0.5-0.10.1-0.00.40.1
Reaction time false alarm rate0.40.50.90.60.60.90.50.8-0.6-0.9-0.9-0.8-0.1
Reaction time premature initiation rate0.40.51.6-0.7-0.70.0-0.8-0.2-1.2-0.5-0.60.4-1.2
Reaction time premature initiations1.01.54.2-1.2-1.2-0.0-1.3-0.3-2.0-0.7-0.80.9-1.9
Std. dev. reaction times1.41.93.3-1.4-1.4-1.8-1.1-1.70.61.61.61.6-0.0
Reaction time trials completed0.30.41.4-0.5-0.50.1-0.50.1-1.2-0.5-0.60.4-0.9
Reaction time trials AUC0.20.31.0-0.1-0.10.4-0.20.4-1.0-0.7-0.70.1-0.6
Social response proportion0.20.20.6-0.1-0.1-0.6-0.2-0.50.10.80.80.5-0.2
Social responses1.82.32.8-1.5-1.5-1.7-1.6-1.6-0.51.71.61.6-1.5
Social time0.20.30.70.60.60.30.60.20.90.10.1-0.60.8
Conditioned locomotion0.20.20.6-0.3-0.30.3-0.30.3-0.8-0.6-0.70.1-0.6
Cocaine response after cond. corrected0.10.10.2-0.3-0.3-0.4-0.3-0.40.10.30.30.4-0.1
Cocaine response after cond. not corrected0.10.10.30.10.10.40.10.3-0.5-0.4-0.5-0.0-0.3
Cocaine response before conditioning0.60.71.20.90.91.10.81.0-0.4-1.0-1.0-0.90.1
Saline control response1.11.52.41.31.31.51.11.60.3-1.2-1.1-1.60.6
Condit. Reinf. active minus inactive responses1.21.42.61.01.01.40.81.3-1.4-1.6-1.6-1.0-0.3
Condit. Reinf. active-inactive response ratio0.60.71.00.90.91.00.80.9-0.4-1.0-1.0-0.70.3
Condit. Reinf. active responses0.60.83.4-0.3-0.30.5-0.60.3-1.9-0.9-0.90.2-1.5
Condit. Reinf. inactive responses1.01.22.9-1.4-1.4-0.6-1.5-0.6-1.30.10.11.0-1.7
Condit. Reinf. lever presses0.10.10.2-0.4-0.4-0.2-0.4-0.2-0.20.10.10.4-0.4
Condit. Reinf. lever reinforcers received0.40.62.1-0.0-0.00.6-0.20.5-1.5-0.9-0.9-0.1-1.1
Pavlov. Cond. lever latency0.40.61.20.60.61.00.60.9-0.5-1.1-1.1-0.90.1
Pavlov. Cond. magazine entry latency0.60.71.31.01.00.71.10.70.4-0.6-0.6-0.81.1
Pavlov. Cond. change in total contacts0.40.50.80.90.90.80.80.80.0-0.7-0.6-0.80.5
Pavlov. Cond. index score0.10.10.10.30.30.30.30.3-0.1-0.2-0.2-0.10.2
Pavlov. Cond. latency score0.00.00.10.20.20.20.20.2-0.2-0.2-0.3-0.00.0
Pavlov. Cond. lever contacts0.20.20.5-0.4-0.4-0.6-0.4-0.60.10.70.70.5-0.3
Pavlov. Cond. magazine entry number1.21.42.4-1.4-1.4-1.0-1.5-1.1-0.80.80.71.3-1.6
Pavlov. Cond. intertrial magazine entries0.60.71.70.30.31.00.10.8-1.3-1.3-1.3-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.60.70.60.60.6-0.1-0.5-0.5-0.40.4
Pavlov. Cond. response bias0.20.20.50.70.70.30.70.30.5-0.0-0.0-0.40.7
Conditioned reinforcement - actives1.51.53.0-1.4-1.4-0.7-1.5-0.9-1.60.20.11.4-1.7
Conditioned reinforcement - inactives1.41.63.0-1.4-1.3-0.9-1.4-1.3-1.60.50.31.3-1.7
Conditioned locomotion2.42.83.6-1.8-1.8-1.7-1.9-1.8-0.81.61.51.9-1.8
Intermittent access intake day 1-15 change4.84.87.0-2.6-2.6-2.2-2.5-2.2-1.41.61.42.7-2.2
Intermittent access intake escalation5.75.68.5-2.9-2.9-2.5-2.8-2.5-1.21.71.62.9-2.1
Intermittent access intake escalation 22.82.74.5-2.0-2.0-1.8-1.9-1.7-0.81.31.12.1-1.3
Intermitt. access day 1 inactive lever presses0.20.30.7-0.2-0.2-0.7-0.2-0.60.40.80.80.40.1
Intermitt. access day 15 inactive lever presses3.33.64.9-1.8-1.8-2.1-2.0-2.2-0.52.12.12.0-1.9
Intermitt. access escalation Index0.50.41.00.80.80.70.71.0-0.1-0.6-0.6-0.60.3
Intermittent access day 1 total infusions0.30.41.7-0.0-0.00.4-0.20.1-1.3-0.5-0.50.0-1.0
Intermittent access day 15 total infusions4.85.38.5-2.7-2.7-1.9-2.8-2.0-2.31.00.82.7-2.9
Intermittent access terminal intake (last 3 days)2.93.14.8-2.0-2.0-1.5-2.1-1.6-1.71.00.92.1-2.2
Intermittent access total infusions1.21.33.2-1.2-1.2-0.6-1.4-0.7-1.70.10.01.2-1.8
Intermittent access day 1 locomotion0.20.20.8-0.2-0.10.1-0.3-0.1-0.9-0.2-0.20.1-0.8
Intermittent access day 15 total locomotion2.62.83.9-1.9-1.9-1.7-2.0-1.8-0.81.31.31.8-1.7
Intermittent access total locomotion0.10.10.4-0.2-0.2-0.0-0.3-0.1-0.6-0.0-0.00.1-0.7
Intermittent access standard deviation2.32.43.9-1.7-1.7-1.6-1.7-1.5-1.41.10.92.0-1.7
Cocaine induced anxiety1.51.72.41.51.51.51.41.50.1-1.4-1.3-1.40.9
Post-drug Anxiety0.30.40.90.70.70.50.70.50.9-0.10.0-0.70.7
Baseline Anxiety0.60.61.4-0.6-0.6-0.9-0.6-0.90.51.11.20.6-0.3
Lifetime Intake1.01.22.7-1.2-1.2-0.6-1.3-0.7-1.40.20.11.1-1.7
Incentive Sensitization - Responses4.14.16.8-2.3-2.3-1.7-2.4-1.8-2.01.10.92.3-2.6
Incentive Sensitization - Breakpoint4.24.37.1-2.4-2.4-1.7-2.5-1.9-2.11.10.92.3-2.7
Progressive ratio test 1 active lever presses0.80.92.4-0.9-0.9-0.6-1.1-0.8-1.20.40.30.9-1.5
Progressive ratio test 1 breakpoint0.80.82.2-0.9-0.9-0.6-1.1-0.8-1.00.50.50.9-1.5
Progressive ratio test 1 inactive lever presses1.01.13.0-0.9-0.9-0.7-1.1-1.0-1.40.60.50.9-1.7
Progressive ratio test 2 active lever presses4.04.27.7-2.4-2.4-1.6-2.5-1.8-2.11.00.82.2-2.8
Progressive ratio test 2 breakpoint4.34.89.8-2.4-2.4-1.7-2.7-1.9-2.41.10.92.3-3.1
Progressive ratio test 2 inactive lever presses1.82.13.1-1.6-1.6-1.3-1.7-1.4-1.21.00.91.6-1.7
Total sessions with >9 infusions0.50.61.0-0.8-0.8-0.7-0.9-0.8-0.50.70.70.7-1.0
Short access day 1 total inactive lever presses1.92.12.9-1.4-1.4-1.6-1.4-1.7-0.01.71.71.6-1.1
Short access day 10 total inactive lever presses0.70.81.41.11.10.51.10.51.20.10.2-0.91.2
Short access day 1 total infusions0.10.10.2-0.4-0.4-0.3-0.4-0.20.10.40.40.3-0.3
Short access day 10 total infusions0.20.20.3-0.5-0.5-0.5-0.5-0.5-0.10.50.50.5-0.4
Short access total infusions0.50.51.4-0.7-0.7-0.4-0.9-0.6-0.90.30.20.6-1.2
Short access day 1 locomotion0.00.00.00.10.20.10.10.10.10.10.1-0.2-0.1
Short access day 10 total locomotion0.20.20.30.50.50.30.60.40.4-0.2-0.2-0.50.6
Short access total locomotion0.10.20.40.40.40.00.4-0.00.70.30.4-0.40.4
Compulsive drug intake0.40.41.7-0.2-0.20.1-0.4-0.1-1.3-0.3-0.40.3-1.1
One hour access (0.3 mA shock)5.76.613.7-2.9-2.8-1.7-3.1-2.0-3.20.80.62.9-3.7
One hour access (shock baseline)1.92.23.4-1.8-1.8-1.2-1.8-1.3-1.50.70.51.8-1.8
Number of responses in last shaping day2.72.74.6-2.1-2.1-1.5-2.1-1.4-0.81.11.01.9-1.8
Context. condit. distance diff. score0.91.14.2-0.1-0.10.8-0.30.4-2.1-1.3-1.4-0.3-1.4
Locomotion velocity, session 11.61.76.40.10.0-1.10.4-0.92.51.51.60.21.8
Locomotion distance, session 10.10.10.70.00.0-0.20.1-0.20.80.30.4-0.10.6
Locomotion velocity, session 20.30.41.20.30.2-0.40.5-0.31.10.60.6-0.11.1
Locomotion distance, session 20.30.50.70.60.60.60.70.70.3-0.7-0.7-0.70.9
Locomotion velocity, session 30.10.10.3-0.3-0.30.1-0.2-0.0-0.6-0.4-0.40.0-0.4
Locomotion distance, session 30.80.82.30.00.10.90.00.7-1.5-1.4-1.5-0.4-0.6
Stereotopy head waving bouts, day 30.80.91.7-0.8-0.8-1.2-0.7-1.20.71.31.30.9-0.0
Stereotopy head waving duration, day 30.40.51.4-0.2-0.2-0.8-0.3-0.80.61.21.20.5-0.1
Locomotion velocity, session 71.71.92.71.41.41.61.11.4-1.5-1.6-1.6-1.3-0.4
Locomotion distance, session 71.01.22.40.91.01.30.71.1-1.6-1.3-1.4-0.9-0.6
Stereotopy head waving bouts, day 70.40.50.7-0.6-0.7-0.8-0.6-0.70.40.80.80.7-0.1
Stereotopy head waving duration, day 71.61.92.6-1.5-1.5-1.6-1.4-1.50.31.51.51.6-0.7
Locomotion velocity, session 80.10.10.5-0.2-0.2-0.0-0.3-0.1-0.7-0.0-0.10.2-0.6
Locomotion distance, session 80.91.33.00.70.71.40.71.2-1.1-1.7-1.7-1.2-0.1
Degree of sensitization distance1.11.22.61.61.61.11.31.10.1-0.5-0.4-1.30.5
Degree of sensitization stereotypy0.91.01.5-1.2-1.2-1.1-1.2-1.0-0.00.90.91.2-0.6
Condit. Reinf. active minus inactive responses0.91.01.61.11.10.91.20.90.4-0.8-0.8-1.01.3
Condit. Reinf. active-inactive response ratio0.30.31.10.20.2-0.30.4-0.31.00.40.4-0.01.0
Condit. Reinf. active responses0.81.01.80.90.91.20.91.2-0.5-1.3-1.3-0.90.3
Condit. Reinf. inactive responses0.60.71.40.20.30.90.10.9-1.1-1.2-1.2-0.4-0.7
Incentive salience index mean2.02.43.01.61.61.61.71.70.3-1.6-1.6-1.61.5
Condit. Reinf. lever presses2.02.63.41.71.71.71.81.80.8-1.5-1.4-1.91.6
Time in familiar zone, hab. session 10.60.60.9-0.7-0.7-0.9-0.7-0.80.21.01.00.9-0.3
Time in novel zone, hab. session 10.80.81.31.11.10.91.10.80.4-0.7-0.6-1.10.8
Total zone transitions, hab. session 10.00.00.1-0.3-0.3-0.2-0.3-0.20.10.10.10.2-0.1
Total locomotion distance, hab. session 10.81.12.01.01.00.91.21.11.0-0.8-0.7-1.21.4
Locomotion velocity, hab. session 11.31.92.91.41.31.31.51.51.1-1.1-1.1-1.61.7
Time in familiar zone, hab. session 20.40.41.1-0.3-0.3-0.8-0.2-0.60.81.01.00.50.3
Time in novel zone, hab. session 20.00.00.1-0.1-0.10.0-0.2-0.1-0.2-0.1-0.10.1-0.2
Total zone transitions, hab. session 20.20.30.7-0.4-0.4-0.6-0.3-0.50.80.60.60.30.4
Total locomotion distance, hab. session 20.20.20.80.30.20.10.40.20.8-0.1-0.1-0.40.9
Locomotion velocity, hab. session 20.40.51.20.60.60.60.80.70.8-0.5-0.5-0.81.1
Novel to familiar place preference ratio0.30.30.90.50.50.60.30.5-1.0-0.7-0.8-0.3-0.4
Novelty place preference0.20.31.00.30.40.50.20.3-1.0-0.5-0.6-0.1-0.5
Time in novel zone, NPP test0.30.30.80.50.50.50.40.4-0.9-0.5-0.6-0.3-0.3
Total zone transitions, NPP test0.50.71.20.90.90.81.00.80.7-0.6-0.6-1.11.1
Total locomotion distance, NPP test1.62.23.81.61.61.21.81.41.3-0.9-0.9-1.71.9
Locomotion velocity, NPP test1.82.63.61.81.71.51.91.71.1-1.2-1.2-1.91.9
Pavlov. Cond. lever latency3.03.85.0-2.1-2.1-2.2-2.0-2.20.22.12.12.2-1.2
Pavlov. Cond. magazine entry latency0.81.02.11.01.00.81.20.90.6-0.8-0.9-1.01.4
Pavlov. Cond. change in total contacts0.50.61.60.80.80.51.00.60.6-0.5-0.5-0.61.3
Pavlov. Cond. index score2.32.94.11.71.71.91.71.9-0.1-2.0-2.0-1.81.3
Pavlov. Cond. latency score3.14.05.72.02.02.32.02.3-0.3-2.4-2.4-2.11.3
Pavlov. Cond. lever contacts3.13.64.82.02.02.22.02.1-0.0-2.1-2.1-2.11.3
Pavlov. Cond. magazine entry number0.10.10.5-0.3-0.3-0.2-0.5-0.2-0.20.40.40.2-0.7
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.0-0.00.5-0.10.6-0.8-0.8-0.8-0.1-0.5
Pavlov. Cond. lever-magazine prob. diff.2.53.24.11.81.82.01.92.00.2-2.0-2.0-1.91.6
Pavlov. Cond. response bias0.70.81.90.90.90.71.10.70.6-0.7-0.7-0.91.4
Bone: apparent density4.98.114.3-3.2-3.2-2.3-3.5-2.4-2.81.51.23.3-3.8
Bone surface4.07.010.0-2.9-2.9-2.5-3.1-2.6-2.21.91.73.1-3.2
Bone volume3.55.811.3-2.7-2.7-1.9-2.9-2.1-2.71.21.02.7-3.4
Bone: connectivity density3.65.78.0-2.6-2.6-2.3-2.8-2.4-1.91.81.62.8-2.8
Bone: cortical apparent density0.81.03.01.11.10.21.10.31.70.50.7-0.71.4
Bone: cortical area1.42.17.4-1.3-1.3-0.3-1.5-0.5-2.7-0.4-0.51.2-2.5
Bone: cortical porosity0.30.30.70.80.80.50.70.40.2-0.2-0.1-0.70.4
Bone: cortical porosity0.10.10.20.40.40.20.30.2-0.3-0.1-0.1-0.3-0.1
Bone: cortical thickness0.20.30.7-0.1-0.10.5-0.20.5-0.8-0.8-0.80.0-0.5
Bone: cortical thickness0.60.81.10.90.90.91.01.00.5-0.8-0.7-0.80.9
Bone: cortical tissue density0.81.03.21.01.00.11.10.21.80.60.7-0.71.5
Bone: elastic displacement1.21.35.40.50.5-0.60.7-0.42.31.31.4-0.21.7
Bone: elastic work0.81.03.10.40.4-0.70.5-0.61.71.41.40.01.2
Bone: endosteal estimation3.06.415.2-2.5-2.4-1.9-2.8-2.2-3.41.31.12.6-3.9
Bone: endosteal perimeter3.36.814.6-2.7-2.7-2.0-3.0-2.2-3.31.21.02.8-3.8
Bone: final force0.71.12.7-1.1-1.1-0.6-1.2-0.8-1.50.20.11.1-1.6
Bone: final moment1.01.62.9-1.4-1.4-1.1-1.5-1.2-1.30.70.61.4-1.7
Bone: marrow area3.26.815.9-2.6-2.5-2.0-2.9-2.3-3.41.41.22.7-4.0
Bone: maximum diameter4.68.420.5-3.1-3.0-1.8-3.4-2.0-4.10.80.53.0-4.5
Bone: maximum force2.03.47.0-2.0-2.0-1.4-2.2-1.6-2.10.90.82.0-2.6
Bone: maximum moment2.54.47.1-2.3-2.2-1.9-2.4-2.0-1.81.41.32.4-2.7
Bone: minimum diameter4.48.121.2-2.8-2.8-1.5-3.2-1.9-4.40.50.22.8-4.6
Bone: periosteal estimation3.36.716.9-2.6-2.6-1.7-3.0-1.9-3.70.90.72.6-4.1
Bone: periosteal perimeter2.44.011.1-1.9-1.9-0.9-2.2-1.1-3.30.1-0.21.8-3.3
Bone: post-yield work2.23.16.6-1.9-1.9-1.1-2.1-1.2-2.40.30.11.9-2.6
Bone: stiffness1.21.97.9-0.8-0.80.2-1.2-0.2-2.8-0.7-0.80.7-2.6
Bone: tissue strength1.21.22.4-0.8-0.8-1.3-0.8-1.40.51.51.50.9-0.4
Bone: trabecular number4.77.210.5-3.1-3.0-2.4-3.2-2.5-2.31.71.53.2-3.2
Bone: trabecular spacing2.02.63.71.91.81.51.91.61.2-1.2-1.1-1.81.9
Bone: trabecular thickness3.34.06.6-2.4-2.4-1.7-2.5-1.7-1.91.00.92.2-2.6
Bone: trabecular tissue density0.30.41.6-0.3-0.30.1-0.6-0.1-1.3-0.2-0.20.3-1.3
Breakpoint value in progressive ratio session0.50.61.30.40.40.90.10.8-1.1-1.0-1.0-0.6-0.8
Distance traveled before self-admin0.80.81.11.01.00.91.11.0-0.0-0.9-0.9-1.10.8
Distance traveled after self-admin0.10.10.40.30.3-0.30.2-0.4-0.00.60.60.0-0.1
Delta time in closed arm before/after self-admin0.30.30.50.50.50.50.60.7-0.0-0.5-0.6-0.50.5
Delta time in open arm before/after self-admin0.40.40.70.80.90.70.80.70.1-0.5-0.5-0.70.4
Diff in mean of infusions in LGA sessions0.30.40.90.60.60.70.40.6-1.0-0.6-0.7-0.5-0.4
Extinction: sum of active levers before priming0.20.20.80.20.20.40.10.3-0.9-0.5-0.6-0.4-0.6
Active lever presses in extinction session 61.00.92.10.60.71.10.41.0-1.4-1.2-1.3-0.6-0.6
Delta distance traveled before/after self-admin0.70.71.6-0.6-0.6-0.7-0.9-0.9-0.80.80.80.8-1.3
Delta ambulatory time before/after self-admin0.91.03.0-0.8-0.8-0.7-1.1-1.0-1.20.70.60.9-1.7
Time in closed arm before self-admin0.50.61.11.01.00.71.00.70.3-0.5-0.5-0.80.8
Time in closed arm after self-admin3.33.44.52.12.12.02.12.00.2-1.8-1.7-2.11.5
Time in open arm before self-admin0.50.50.8-0.8-0.8-0.9-0.7-0.90.50.90.90.7-0.1
Time in open arm after self-admin0.70.81.2-1.1-1.1-0.9-1.0-0.9-0.20.70.71.1-0.7
Sum of active levers in priming session hrs 5-60.30.30.7-0.1-0.1-0.60.1-0.30.90.80.80.40.7
Time to tail flick, vehicle, before self-admin0.50.52.10.40.4-0.30.4-0.11.40.91.0-0.20.8
Time to tail flick, vehicle, after self-admin2.42.64.41.41.42.01.21.7-1.5-2.1-2.1-1.6-0.2
Time to tail flick, test, before self-admin0.90.93.60.40.40.90.10.5-1.9-1.1-1.1-0.6-1.2
Time to tail flick, test, after self-admin0.50.51.31.11.10.51.00.50.3-0.00.0-0.80.5
Delta time to tail flick, vehicle, before/after SA3.73.68.40.90.92.10.61.8-2.8-2.8-2.9-1.2-1.1
Delta time to tail flick, test, before/after SA0.10.10.20.20.20.00.20.20.40.10.2-0.00.4
Ambulatory time before self-admin1.11.11.81.31.20.91.41.00.6-0.7-0.7-1.21.3
Ambulatory time after self-admin0.10.10.30.50.50.00.4-0.2-0.30.20.2-0.3-0.1
Total heroin consumption0.30.31.1-0.4-0.4-0.0-0.6-0.1-1.0-0.2-0.20.3-1.1
Area under the delay curve0.70.71.21.11.10.91.00.90.4-0.6-0.5-0.90.8
Delay disc. indifference point, 0s delay2.62.84.21.81.82.11.62.0-0.8-1.9-1.9-1.70.5
Delay disc. indifference point, 16s delay0.10.10.2-0.1-0.1-0.3-0.2-0.2-0.00.40.40.2-0.4
Delay disc. indifference point, 2s delay0.20.20.40.60.60.20.60.30.60.20.2-0.30.6
Delay disc. indifference point, 24s delay1.11.11.81.31.31.11.21.20.4-0.7-0.7-1.20.8
Delay disc. indifference point, 4s delay1.31.42.11.41.41.41.21.4-0.1-1.2-1.2-1.30.6
Delay disc. indifference point, 8s delay1.41.42.81.41.40.71.50.81.6-0.1-0.0-1.11.7
Delay discount exponential model param0.70.71.2-1.1-1.1-0.9-1.1-0.9-0.40.60.50.9-0.8
Delay discount hyperbolic model param0.60.71.1-1.1-1.1-0.8-1.0-0.8-0.50.40.40.8-0.8
Fecal boli incidents, locomotor time 10.70.81.21.11.11.10.90.9-0.5-0.9-0.9-1.00.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.5-0.5-0.4-0.3-0.30.30.20.20.30.1
Time >=10cm from walls, locomotor time 11.61.66.5-0.5-0.50.8-0.70.3-2.5-1.5-1.60.0-1.8
Bouts of movement, locomotor time 10.10.20.3-0.4-0.40.0-0.50.1-0.6-0.3-0.30.4-0.5
Total resting periods, locomotor time 10.20.20.5-0.3-0.30.2-0.40.2-0.7-0.4-0.40.2-0.6
Rest time, locomotor task time 10.00.00.10.10.2-0.00.0-0.00.10.30.30.0-0.1
Distance moved, locomotor task time 10.50.50.80.70.70.80.70.8-0.2-0.9-0.9-0.80.4
Vertical activity count, locomotor time 10.10.10.3-0.5-0.5-0.4-0.4-0.3-0.10.10.00.6-0.0
Time >=10cm from walls, locomotor time 21.41.52.91.11.11.51.01.2-1.1-1.7-1.7-1.10.0
Bouts of movement, locomotor time 22.22.34.71.71.71.21.81.41.6-0.8-0.7-1.62.2
Total resting periods, locomotor time 22.42.54.61.81.71.41.91.51.5-1.0-0.9-1.72.1
Rest time, locomotor task time 20.50.51.10.60.61.00.51.0-0.2-1.1-1.0-0.70.3
Distance moved, locomotor task time 20.20.20.40.50.50.50.40.4-0.7-0.5-0.6-0.5-0.2
Vertical activity count, locomotor time 20.10.10.40.20.2-0.40.3-0.40.30.60.60.10.3
Weight adjusted by age0.10.20.40.50.50.10.40.20.60.30.3-0.20.4
Seeking ratio, delayed vs. immediate footshock0.20.20.40.30.30.60.20.5-0.4-0.6-0.6-0.5-0.2
Locomotion in novel chamber0.60.71.3-1.1-1.1-0.6-1.1-0.4-1.20.1-0.00.9-1.2
Locomotion in novel chamber post-restriction0.91.03.7-0.5-0.50.6-0.70.4-1.9-1.2-1.30.1-1.5
Progressive ratio0.50.61.7-0.1-0.20.8-0.10.7-0.9-1.3-1.3-0.3-0.4
Food seeking constrained by brief footshock1.61.94.3-1.7-1.7-0.6-1.7-0.8-2.1-0.4-0.61.2-1.8
Seeking ratio, punishment vs. effort0.20.30.5-0.4-0.4-0.7-0.4-0.7-0.30.60.60.5-0.4
Run reversals in cocaine runway, females0.30.30.90.10.0-0.50.2-0.50.90.70.70.10.7
Run reversals in cocaine runway, males0.00.00.1-0.2-0.20.1-0.20.10.2-0.2-0.10.00.1
Latency to leave start box in cocaine runway0.20.20.6-0.4-0.4-0.1-0.4-0.1-0.8-0.2-0.20.2-0.6
Latency to leave start box in cocaine runway, F0.00.00.30.00.00.1-0.00.1-0.5-0.2-0.2-0.1-0.3
Latency to leave start box in cocaine runway, M0.30.30.7-0.8-0.8-0.3-0.7-0.3-0.7-0.1-0.20.6-0.6
Cd content in liver0.60.71.0-0.8-0.8-1.0-0.7-0.90.60.90.91.00.1
Co content in liver1.41.73.6-0.7-0.7-1.5-0.5-1.41.61.91.91.00.7
Cu content in liver1.41.76.10.20.1-1.10.3-0.82.51.81.90.31.4
Fe content in liver1.31.55.50.90.80.31.20.52.30.00.1-0.92.3
K content in liver2.42.43.31.71.71.71.71.70.5-1.4-1.4-1.81.4
Mg content in liver1.51.52.81.31.31.01.41.11.2-0.8-0.7-1.41.7
Mn content in liver1.11.22.91.11.00.81.21.01.5-0.6-0.5-1.11.7
Na content in liver4.24.56.02.32.32.22.42.31.3-1.8-1.7-2.52.2
Rb content in liver0.30.40.60.70.70.80.50.7-0.6-0.7-0.7-0.6-0.1
Se content in liver7.99.634.12.62.60.53.21.05.80.81.2-2.35.4
Sr content in liver2.52.33.4-1.5-1.5-1.8-1.4-1.80.31.81.81.6-0.8
Zn content in liver5.76.213.32.92.91.63.11.83.0-0.7-0.5-2.73.6