Hub : Genes

R3hcc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016777 0.15 0.18 1.1e-10 0.09 0.08 0.08 0.08 8.5e-10 1.8e-09 1.3e-09 1.7e-09
2 Adipose mRNA stability ENSRNOG00000016777 0.28 0.29 0.0e+00 0.17 0.17 0.17 0.17 1.7e-18 2.7e-18 2.1e-18 2.8e-18
3 BLA gene expression ENSRNOG00000016777 0.15 0.13 1.4e-05 0.08 0.08 0.08 0.08 4.1e-05 4.4e-05 4.0e-05 4.1e-05
4 Brain gene expression ENSRNOG00000016777 0.09 0.09 3.7e-07 0.06 0.07 0.06 0.06 3.8e-06 6.3e-07 1.6e-06 3.3e-06
5 Brain mRNA stability ENSRNOG00000016777 0.08 0.07 5.4e-06 0.05 0.06 0.05 0.05 1.3e-05 3.0e-06 1.1e-05 1.2e-05
6 Liver alternative TSS ENSRNOT00000022706 0.11 0.09 6.8e-11 0.09 0.08 0.09 0.09 7.3e-10 1.3e-09 7.4e-10 9.4e-10
7 Liver alternative TSS ENSRNOT00000101142 0.11 0.09 4.6e-11 0.09 0.09 0.09 0.09 5.6e-10 1.1e-09 5.6e-10 6.9e-10
8 Liver gene expression ENSRNOG00000016777 0.43 0.23 0.0e+00 0.38 0.37 0.37 0.38 4.3e-44 3.1e-43 1.3e-43 6.0e-44
9 Liver mRNA stability ENSRNOG00000016777 0.11 0.11 9.3e-11 0.09 0.09 0.09 0.09 3.9e-10 4.1e-10 2.8e-10 3.6e-10
10 NAcc gene expression ENSRNOG00000016777 0.07 0.07 1.4e-04 0.04 0.05 0.04 0.04 2.8e-04 1.7e-04 2.9e-04 2.9e-04
11 NAcc mRNA stability ENSRNOG00000016777 0.04 0.04 8.2e-03 0.02 0.01 0.03 0.01 2.2e-02 2.8e-02 1.6e-03 3.9e-02
12 PL gene expression ENSRNOG00000016777 0.14 0.12 5.3e-08 0.09 0.09 0.09 0.09 2.2e-07 1.8e-07 1.9e-07 1.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.41.41.7-1.2-1.21.11.31.21.1-1.1-1.1-1.11.21.31.2
BMI without tail0.71.41.61.21.2-1.2-0.9-1.2-1.31.21.31.2-1.2-1.0-1.2
Body weight0.41.71.7-1.3-1.31.31.31.31.3-1.3-1.3-1.31.31.31.3
Epididymis fat weight2.25.25.52.32.3-2.3-2.1-2.3-2.32.32.32.3-2.3-2.3-2.3
Glucose0.00.00.10.20.2-0.1-0.2-0.1-0.10.10.10.1-0.1-0.2-0.1
Heart weight0.00.00.00.10.1-0.20.0-0.1-0.10.20.10.2-0.20.1-0.2
Left kidney weight0.20.71.8-0.9-0.90.61.40.80.6-0.6-0.6-0.60.80.90.8
Right kidney weight0.10.40.60.50.5-0.8-0.1-0.6-0.70.80.70.8-0.6-0.5-0.6
Tail length0.92.62.71.61.6-1.7-1.3-1.6-1.71.71.71.7-1.6-1.5-1.6
Length with tail0.10.20.2-0.5-0.50.50.50.50.5-0.5-0.5-0.50.50.50.5
Length without tail3.78.08.3-2.9-2.92.82.62.92.8-2.8-2.8-2.82.92.72.9
Liver weight, left2.23.53.7-1.9-1.91.91.81.91.8-1.9-1.8-1.91.91.91.9
Liver weight, right0.71.21.2-1.1-1.11.11.01.11.1-1.1-1.1-1.11.11.01.1
Parametrial fat weight3.56.87.42.62.6-2.7-2.2-2.6-2.72.72.72.7-2.6-2.5-2.6
Retroperitoneal fat weight0.20.81.10.80.8-1.0-0.2-0.8-1.01.01.01.0-0.8-0.9-0.8
Intraocular pressure0.50.81.20.90.9-0.7-1.1-0.9-0.80.70.80.7-0.9-1.1-0.9
Extensor digitorum longus weight12.349.551.1-7.1-7.17.16.37.17.1-7.1-7.1-7.17.17.27.1
Soleus weight0.92.63.1-1.7-1.71.61.81.71.5-1.6-1.5-1.61.71.31.7
Tibialis anterior weight7.927.327.9-5.3-5.35.34.85.35.2-5.3-5.2-5.35.35.35.3
Tibia length1.23.33.61.81.8-1.9-1.5-1.8-1.91.91.91.9-1.8-1.5-1.8
Number of licking bursts0.00.00.1-0.1-0.10.10.30.10.0-0.1-0.0-0.10.10.10.1
Food consumed during 24 hour testing period0.20.30.40.50.5-0.6-0.2-0.5-0.60.60.60.6-0.5-0.6-0.5
Times rat made contact with spout0.40.50.50.70.7-0.7-0.6-0.7-0.70.70.70.7-0.7-0.4-0.7
Mean time between licks in bursts2.02.83.01.71.7-1.7-1.5-1.7-1.71.71.71.7-1.7-1.7-1.7
Mean num. licks in bursts0.40.40.70.70.7-0.6-0.8-0.7-0.60.60.60.6-0.7-0.5-0.7
Std. dev. time between licks in bursts1.31.61.71.31.3-1.3-1.3-1.3-1.21.31.21.3-1.3-1.1-1.3
Water consumed over 24 hours1.41.61.9-1.3-1.31.31.21.31.2-1.3-1.2-1.31.31.41.3
Indifference point 0 sec2.33.64.71.91.9-1.8-1.9-1.9-1.91.81.91.8-1.9-2.2-1.9
Indifference point AUC0.50.60.8-0.7-0.70.90.60.80.8-0.9-0.8-0.90.80.70.8
Indifference point function ln k0.00.00.00.10.1-0.20.0-0.1-0.20.20.20.2-0.1-0.0-0.1
Indifference point function log k0.00.00.00.10.1-0.20.0-0.1-0.20.20.20.2-0.1-0.0-0.1
Delay discounting total patch changes 0 sec1.93.03.91.71.7-1.7-1.7-1.7-1.71.71.71.7-1.7-2.0-1.7
Delay discounting total patch changes 12 sec0.71.01.51.11.1-0.9-1.0-1.0-1.00.91.00.9-1.0-1.2-1.0
Delay discounting total patch changes 18 sec1.92.53.41.71.7-1.5-1.7-1.6-1.51.51.51.5-1.6-1.9-1.6
Delay discounting total patch changes 24 sec0.00.00.30.20.20.0-0.5-0.1-0.0-0.00.0-0.0-0.1-0.4-0.1
Delay discounting total patch changes 6 sec0.30.50.80.80.8-0.6-0.9-0.7-0.70.60.70.6-0.7-0.8-0.7
Delay discounting time to switch 0 sec0.71.11.81.11.1-1.0-1.3-1.1-0.91.00.91.0-1.1-1.0-1.1
Delay discounting water rate 0 sec0.30.51.0-0.8-0.80.61.00.70.6-0.6-0.6-0.60.70.70.7
Delay discounting water rate 12 sec0.71.02.1-1.1-1.10.81.41.00.8-0.8-0.8-0.81.01.41.0
Delay discounting water rate 18 sec2.93.94.8-2.1-2.11.92.22.01.8-1.9-1.8-1.92.02.22.0
Delay discounting water rate 24 sec0.10.10.7-0.4-0.40.10.80.30.1-0.1-0.1-0.10.30.60.3
Delay discounting water rate 6 sec2.13.04.1-1.8-1.81.62.01.81.6-1.6-1.6-1.61.81.81.8
Locomotor activity1.42.22.4-1.5-1.51.51.41.51.5-1.4-1.5-1.41.51.61.5
Locomotor testing distance0.00.00.00.00.0-0.10.1-0.0-0.10.10.10.1-0.1-0.0-0.1
Locomotor testing rearing0.20.30.40.50.5-0.6-0.5-0.6-0.60.60.60.6-0.6-0.5-0.6
Light reinforcement 13.36.06.62.52.5-2.4-2.6-2.5-2.32.42.32.4-2.5-2.3-2.5
Light reinforcement 21.31.73.31.41.4-1.2-1.8-1.4-1.11.21.11.2-1.3-1.1-1.3
Reaction time number correct0.50.71.4-0.9-0.90.81.20.90.7-0.8-0.7-0.80.90.80.9
Reaction time mean minus median0.10.20.3-0.3-0.30.50.10.40.5-0.5-0.5-0.50.40.00.4
Reaction time mean minus median AUC0.10.10.2-0.3-0.30.50.00.40.5-0.5-0.5-0.50.40.10.4
Reaction time num false alarms0.00.10.4-0.2-0.20.00.70.2-0.0-0.00.0-0.00.20.20.2
Reaction time num false alarms AUC0.00.00.2-0.1-0.1-0.20.5-0.0-0.20.20.20.2-0.0-0.0-0.0
Reaction time trials correct on left0.50.71.4-0.9-0.90.81.20.90.7-0.8-0.7-0.80.90.80.9
Reaction time trials on left0.40.51.1-0.8-0.80.61.10.80.6-0.7-0.6-0.70.80.60.8
Reaction time mean0.20.30.4-0.4-0.40.60.00.50.7-0.6-0.7-0.60.50.50.5
Reaction time mean AUC0.40.50.7-0.6-0.60.80.20.70.8-0.8-0.8-0.80.70.60.7
Median of all reaction times0.10.10.2-0.2-0.20.4-0.20.30.4-0.4-0.4-0.40.30.40.3
Reaction time omissions2.33.04.41.81.8-1.6-2.1-1.8-1.61.61.61.6-1.7-1.9-1.7
Reaction time false alarm rate0.10.20.30.40.4-0.5-0.1-0.4-0.50.50.50.5-0.4-0.4-0.4
Reaction time premature initiation rate1.41.92.4-1.3-1.31.50.81.41.5-1.5-1.5-1.51.41.41.4
Reaction time premature initiations2.02.93.2-1.7-1.71.81.41.71.8-1.8-1.8-1.81.71.71.7
Std. dev. reaction times0.20.20.4-0.4-0.40.60.00.50.6-0.6-0.6-0.60.50.10.5
Reaction time trials completed0.40.51.1-0.8-0.80.61.10.80.6-0.7-0.6-0.70.80.60.8
Reaction time trials AUC0.30.51.1-0.7-0.70.61.00.70.5-0.6-0.5-0.60.70.60.7
Social response proportion0.10.10.2-0.3-0.30.20.40.30.2-0.2-0.2-0.20.30.40.3
Social responses1.11.41.91.21.2-1.2-1.0-1.2-1.21.21.21.2-1.2-1.4-1.2
Social time0.40.50.60.60.6-0.8-0.4-0.7-0.70.80.70.8-0.7-0.7-0.7
Conditioned locomotion0.00.00.20.20.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.4-0.2
Cocaine response after cond. corrected0.20.30.3-0.5-0.50.50.50.50.5-0.5-0.5-0.50.50.50.5
Cocaine response after cond. not corrected0.20.20.2-0.4-0.40.40.40.40.4-0.4-0.4-0.40.40.50.4
Cocaine response before conditioning0.10.10.20.40.4-0.4-0.5-0.4-0.40.40.40.4-0.4-0.3-0.4
Saline control response0.20.30.40.50.5-0.5-0.6-0.5-0.40.50.40.5-0.5-0.5-0.5
Condit. Reinf. active minus inactive responses0.30.40.40.60.6-0.6-0.4-0.6-0.70.60.70.6-0.6-0.7-0.6
Condit. Reinf. active-inactive response ratio0.10.20.3-0.4-0.40.40.40.40.4-0.4-0.4-0.40.40.50.4
Condit. Reinf. active responses0.91.21.51.11.1-1.1-0.8-1.1-1.21.11.21.1-1.1-1.2-1.1
Condit. Reinf. inactive responses2.32.93.81.71.7-1.7-1.4-1.7-1.71.71.71.7-1.7-1.9-1.7
Condit. Reinf. lever presses0.10.10.10.30.3-0.3-0.2-0.3-0.30.30.30.3-0.3-0.4-0.3
Condit. Reinf. lever reinforcers received0.60.81.00.90.9-0.9-0.6-0.9-1.00.91.00.9-0.9-1.0-0.9
Pavlov. Cond. lever latency0.30.50.50.70.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.10.30.3-0.3-0.2-0.3-0.30.30.30.3-0.3-0.3-0.3
Pavlov. Cond. change in total contacts1.62.22.3-1.5-1.51.51.31.51.5-1.5-1.5-1.51.51.51.5
Pavlov. Cond. index score0.50.60.6-0.8-0.80.80.70.80.8-0.8-0.8-0.80.80.80.8
Pavlov. Cond. latency score0.30.40.4-0.6-0.60.60.60.60.6-0.6-0.6-0.60.60.60.6
Pavlov. Cond. lever contacts0.40.50.5-0.7-0.70.70.70.70.7-0.7-0.7-0.70.70.70.7
Pavlov. Cond. magazine entry number0.00.10.1-0.2-0.20.20.20.20.2-0.2-0.2-0.20.20.30.2
Pavlov. Cond. intertrial magazine entries6.17.98.42.82.8-2.9-2.4-2.8-2.92.92.92.9-2.8-2.9-2.8
Pavlov. Cond. lever-magazine prob. diff.0.60.70.8-0.9-0.90.90.80.90.9-0.9-0.9-0.90.90.80.9
Pavlov. Cond. response bias0.40.60.6-0.8-0.80.80.80.80.8-0.8-0.8-0.80.80.80.8
Conditioned reinforcement - actives2.72.62.81.71.7-1.6-1.5-1.6-1.61.61.61.6-1.6-1.7-1.6
Conditioned reinforcement - inactives2.93.33.41.81.8-1.8-1.8-1.9-1.71.81.71.8-1.9-1.8-1.9
Conditioned locomotion1.01.21.41.11.1-1.1-0.9-1.1-1.21.11.21.1-1.1-0.9-1.1
Intermittent access intake day 1-15 change2.22.22.91.41.4-1.5-1.0-1.4-1.71.51.71.5-1.5-1.5-1.5
Intermittent access intake escalation1.51.52.01.11.1-1.3-0.7-1.2-1.41.31.41.3-1.2-1.3-1.2
Intermittent access intake escalation 20.50.51.30.60.6-0.7-0.2-0.6-0.90.70.90.7-0.6-1.1-0.6
Intermitt. access day 1 inactive lever presses0.10.10.20.30.3-0.3-0.2-0.3-0.20.30.20.3-0.3-0.5-0.3
Intermitt. access day 15 inactive lever presses0.00.00.40.10.10.0-0.6-0.10.2-0.0-0.2-0.0-0.10.1-0.1
Intermitt. access escalation Index0.50.50.8-0.6-0.60.70.30.60.9-0.7-0.9-0.70.70.40.7
Intermittent access day 1 total infusions0.00.00.20.20.2-0.1-0.4-0.2-0.10.10.10.1-0.2-0.0-0.2
Intermittent access day 15 total infusions1.01.11.31.01.0-1.1-0.9-1.1-1.11.11.11.1-1.1-1.1-1.1
Intermittent access terminal intake (last 3 days)0.20.30.40.40.4-0.5-0.3-0.5-0.60.50.60.5-0.5-0.5-0.5
Intermittent access total infusions0.40.50.50.70.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.6-0.7
Intermittent access day 1 locomotion0.30.30.40.60.6-0.6-0.7-0.6-0.50.60.50.6-0.6-0.5-0.6
Intermittent access day 15 total locomotion1.51.62.21.31.3-1.4-0.8-1.2-1.51.41.51.4-1.3-0.9-1.3
Intermittent access total locomotion0.50.60.70.70.7-0.8-0.6-0.7-0.80.80.80.8-0.7-0.7-0.7
Intermittent access standard deviation1.31.41.91.11.1-1.2-0.7-1.1-1.41.21.41.2-1.2-1.1-1.2
Cocaine induced anxiety0.20.20.3-0.4-0.40.40.10.40.5-0.4-0.5-0.40.40.50.4
Post-drug Anxiety0.50.61.10.70.7-0.7-0.6-0.7-0.70.70.70.7-0.7-1.0-0.7
Baseline Anxiety0.90.91.50.90.9-1.0-0.6-0.9-1.11.01.11.0-0.9-1.2-0.9
Lifetime Intake0.40.50.70.70.7-0.7-0.8-0.7-0.60.70.60.7-0.7-0.5-0.7
Incentive Sensitization - Responses1.01.01.21.01.0-1.0-0.7-1.0-1.11.01.11.0-1.0-0.8-1.0
Incentive Sensitization - Breakpoint1.41.41.61.21.2-1.2-0.9-1.2-1.31.21.31.2-1.2-1.0-1.2
Progressive ratio test 1 active lever presses0.20.20.3-0.5-0.50.50.20.40.6-0.5-0.6-0.50.40.40.4
Progressive ratio test 1 breakpoint0.10.10.2-0.3-0.30.3-0.00.30.4-0.3-0.4-0.30.30.20.3
Progressive ratio test 1 inactive lever presses1.51.62.91.31.3-1.2-1.7-1.3-1.01.21.01.2-1.3-1.3-1.3
Progressive ratio test 2 active lever presses0.20.20.20.50.5-0.5-0.4-0.5-0.40.50.40.5-0.5-0.3-0.5
Progressive ratio test 2 breakpoint0.20.30.30.50.5-0.5-0.5-0.5-0.50.50.50.5-0.5-0.3-0.5
Progressive ratio test 2 inactive lever presses0.30.40.60.70.7-0.6-0.8-0.7-0.50.60.50.6-0.7-0.4-0.7
Total sessions with >9 infusions0.00.00.20.10.1-0.1-0.4-0.20.10.1-0.10.1-0.1-0.2-0.1
Short access day 1 total inactive lever presses0.50.50.90.80.8-0.7-0.9-0.8-0.60.70.60.7-0.8-0.7-0.8
Short access day 10 total inactive lever presses0.40.40.60.60.6-0.6-0.7-0.6-0.50.60.50.6-0.6-0.8-0.6
Short access day 1 total infusions0.10.10.2-0.3-0.30.4-0.10.30.5-0.4-0.5-0.40.30.30.3
Short access day 10 total infusions0.00.00.20.20.2-0.1-0.4-0.20.00.1-0.00.1-0.20.2-0.2
Short access total infusions0.20.20.60.50.5-0.4-0.8-0.5-0.30.40.30.4-0.5-0.1-0.5
Short access day 1 locomotion0.20.20.3-0.5-0.50.50.30.40.5-0.5-0.5-0.50.40.20.4
Short access day 10 total locomotion0.60.71.30.80.8-0.7-1.0-0.8-0.70.70.70.7-0.8-1.1-0.8
Short access total locomotion0.80.81.20.90.9-0.8-1.1-0.9-0.70.80.70.8-0.9-1.1-0.9
Compulsive drug intake0.00.00.2-0.1-0.10.00.50.1-0.1-0.00.1-0.00.10.10.1
One hour access (0.3 mA shock)0.30.30.50.50.5-0.6-0.3-0.6-0.70.60.70.6-0.6-0.5-0.6
One hour access (shock baseline)0.00.00.0-0.0-0.00.0-0.2-0.00.1-0.0-0.1-0.0-0.0-0.0-0.0
Number of responses in last shaping day0.10.10.3-0.0-0.00.2-0.40.00.3-0.2-0.3-0.20.10.50.1
Context. condit. distance diff. score0.81.01.11.01.0-1.0-0.9-1.0-1.01.01.01.0-1.0-1.0-1.0
Locomotion velocity, session 10.20.20.3-0.4-0.40.40.20.40.4-0.4-0.4-0.40.40.50.4
Locomotion distance, session 10.00.00.10.20.2-0.0-0.3-0.1-0.00.00.00.0-0.1-0.2-0.1
Locomotion velocity, session 20.00.00.10.20.2-0.2-0.1-0.2-0.20.20.20.2-0.20.2-0.2
Locomotion distance, session 20.00.00.00.20.2-0.2-0.1-0.2-0.20.20.20.2-0.2-0.2-0.2
Locomotion velocity, session 30.40.50.6-0.7-0.70.80.60.70.7-0.8-0.7-0.80.70.60.7
Locomotion distance, session 30.00.00.20.20.2-0.1-0.2-0.1-0.10.10.10.1-0.1-0.4-0.1
Stereotopy head waving bouts, day 30.70.81.0-0.9-0.91.00.70.91.0-1.0-1.0-1.00.90.90.9
Stereotopy head waving duration, day 32.63.23.5-1.8-1.81.81.51.81.9-1.8-1.9-1.81.81.91.8
Locomotion velocity, session 74.24.64.82.22.2-2.2-2.0-2.2-2.22.22.22.2-2.2-1.9-2.2
Locomotion distance, session 73.34.24.52.02.0-2.1-1.7-2.1-2.12.12.12.1-2.1-2.0-2.1
Stereotopy head waving bouts, day 71.71.92.3-1.5-1.51.31.51.41.3-1.3-1.3-1.31.41.51.4
Stereotopy head waving duration, day 72.42.93.4-1.8-1.81.71.71.71.6-1.7-1.6-1.71.71.81.7
Locomotion velocity, session 80.00.00.00.10.1-0.1-0.1-0.1-0.10.10.10.1-0.10.2-0.1
Locomotion distance, session 80.60.91.01.01.0-0.9-0.9-1.0-1.00.91.00.9-1.0-1.0-1.0
Degree of sensitization distance4.64.65.12.12.1-2.3-1.7-2.2-2.22.32.22.3-2.2-1.9-2.2
Degree of sensitization stereotypy1.11.21.6-1.2-1.21.01.31.11.0-1.0-1.0-1.01.11.21.1
Condit. Reinf. active minus inactive responses0.50.50.7-0.7-0.70.80.30.70.9-0.8-0.9-0.80.70.40.7
Condit. Reinf. active-inactive response ratio2.22.42.9-1.5-1.51.71.01.61.7-1.7-1.7-1.71.61.21.6
Condit. Reinf. active responses0.00.00.10.00.00.1-0.30.00.1-0.1-0.1-0.10.0-0.30.0
Condit. Reinf. inactive responses2.93.43.61.91.9-1.9-1.6-1.9-1.81.91.81.9-1.9-1.8-1.9
Incentive salience index mean0.70.91.1-0.9-0.91.10.50.91.1-1.1-1.1-1.11.00.61.0
Condit. Reinf. lever presses0.20.30.4-0.5-0.50.60.30.60.6-0.6-0.6-0.60.60.30.6
Time in familiar zone, hab. session 10.00.00.0-0.2-0.20.10.20.10.1-0.1-0.1-0.10.10.00.1
Time in novel zone, hab. session 11.31.31.4-1.1-1.11.20.91.11.2-1.2-1.2-1.21.11.21.1
Total zone transitions, hab. session 10.20.30.4-0.5-0.50.60.20.50.6-0.6-0.6-0.60.50.30.5
Total locomotion distance, hab. session 10.00.00.10.10.10.1-0.3-0.00.1-0.1-0.1-0.1-0.0-0.2-0.0
Locomotion velocity, hab. session 10.10.10.30.40.4-0.3-0.6-0.4-0.30.30.30.3-0.3-0.5-0.3
Time in familiar zone, hab. session 21.92.02.1-1.4-1.41.41.41.41.4-1.4-1.4-1.41.41.41.4
Time in novel zone, hab. session 20.70.70.80.90.9-0.8-0.8-0.9-0.80.80.80.8-0.9-0.8-0.9
Total zone transitions, hab. session 21.41.82.0-1.3-1.31.41.01.41.4-1.4-1.4-1.41.41.31.4
Total locomotion distance, hab. session 20.20.30.4-0.5-0.50.60.30.50.6-0.6-0.6-0.60.60.40.6
Locomotion velocity, hab. session 20.50.70.9-0.8-0.80.90.60.90.9-0.9-0.9-0.90.90.70.9
Novel to familiar place preference ratio1.51.61.61.31.3-1.3-1.1-1.3-1.31.31.31.3-1.3-1.2-1.3
Novelty place preference1.21.21.31.11.1-1.1-1.0-1.1-1.11.11.11.1-1.1-1.1-1.1
Time in novel zone, NPP test0.60.60.60.80.8-0.8-0.7-0.8-0.80.80.80.8-0.8-0.7-0.8
Total zone transitions, NPP test0.20.20.50.50.5-0.4-0.7-0.5-0.40.40.40.4-0.5-0.7-0.5
Total locomotion distance, NPP test2.53.54.11.91.9-1.8-2.0-1.9-1.81.81.81.8-1.9-2.0-1.9
Locomotion velocity, NPP test2.43.54.21.91.9-1.8-1.9-1.9-1.81.81.81.8-1.9-2.0-1.9
Pavlov. Cond. lever latency0.00.00.0-0.0-0.00.1-0.00.00.0-0.1-0.0-0.10.00.20.0
Pavlov. Cond. magazine entry latency0.10.10.20.20.2-0.2-0.2-0.2-0.30.20.30.2-0.2-0.4-0.2
Pavlov. Cond. change in total contacts0.91.01.0-1.0-1.01.00.91.01.0-1.0-1.0-1.01.01.01.0
Pavlov. Cond. index score0.00.10.1-0.2-0.20.20.30.20.2-0.2-0.2-0.20.20.10.2
Pavlov. Cond. latency score0.00.00.0-0.1-0.10.10.10.10.1-0.1-0.1-0.10.1-0.00.1
Pavlov. Cond. lever contacts0.00.00.10.10.1-0.1-0.0-0.1-0.10.10.10.1-0.1-0.3-0.1
Pavlov. Cond. magazine entry number0.40.50.50.70.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.5-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.3-0.2-0.4-0.3-0.20.20.20.2-0.3-0.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.4-0.40.40.40.40.4-0.4-0.4-0.40.40.30.4
Pavlov. Cond. response bias0.10.10.2-0.4-0.40.30.40.40.3-0.3-0.3-0.30.40.20.4
Bone: apparent density1.42.42.71.51.5-1.7-1.2-1.6-1.61.71.61.7-1.6-1.3-1.6
Bone surface0.61.01.21.01.0-1.1-0.7-1.0-1.11.11.11.1-1.0-0.8-1.0
Bone volume0.71.21.41.11.1-1.2-0.9-1.1-1.21.21.21.2-1.1-0.8-1.1
Bone: connectivity density2.84.44.92.12.1-2.2-1.7-2.1-2.22.22.22.2-2.1-1.8-2.1
Bone: cortical apparent density0.00.00.10.20.2-0.2-0.3-0.2-0.10.20.10.2-0.2-0.3-0.2
Bone: cortical area0.00.00.00.00.0-0.10.0-0.1-0.10.10.10.1-0.10.2-0.1
Bone: cortical porosity1.41.51.7-1.3-1.31.21.21.21.2-1.2-1.2-1.21.21.31.2
Bone: cortical porosity0.60.60.8-0.8-0.80.80.80.80.7-0.8-0.7-0.80.80.90.8
Bone: cortical thickness0.00.00.00.10.1-0.2-0.1-0.2-0.20.20.20.2-0.2-0.1-0.2
Bone: cortical thickness0.00.00.10.20.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.2-0.2
Bone: cortical tissue density0.00.00.10.20.2-0.1-0.3-0.2-0.10.10.10.1-0.2-0.3-0.2
Bone: elastic displacement0.50.60.60.80.8-0.7-0.8-0.8-0.70.70.70.7-0.8-0.8-0.8
Bone: elastic work0.30.30.60.60.6-0.6-0.6-0.6-0.50.60.50.6-0.6-0.8-0.6
Bone: endosteal estimation0.10.30.7-0.6-0.60.40.60.50.4-0.4-0.4-0.40.50.90.5
Bone: endosteal perimeter0.10.20.4-0.4-0.40.30.50.40.3-0.3-0.3-0.30.40.70.4
Bone: final force0.10.20.3-0.5-0.50.40.40.40.4-0.4-0.4-0.40.40.50.4
Bone: final moment0.10.20.3-0.4-0.40.40.40.40.4-0.4-0.4-0.40.40.50.4
Bone: marrow area0.10.20.5-0.4-0.40.30.50.40.3-0.3-0.3-0.30.40.70.4
Bone: maximum diameter0.30.61.1-0.8-0.80.70.80.80.7-0.7-0.7-0.70.81.10.8
Bone: maximum force0.30.40.8-0.7-0.70.60.60.60.6-0.6-0.6-0.60.60.90.6
Bone: maximum moment0.10.20.6-0.5-0.50.50.40.50.5-0.5-0.5-0.50.50.80.5
Bone: minimum diameter0.20.30.9-0.6-0.60.40.60.50.4-0.4-0.4-0.40.51.00.5
Bone: periosteal estimation0.00.10.4-0.3-0.30.20.40.20.2-0.2-0.2-0.20.20.60.2
Bone: periosteal perimeter0.00.00.2-0.2-0.20.00.30.10.0-0.0-0.0-0.00.10.40.1
Bone: post-yield work0.10.20.20.40.4-0.5-0.4-0.5-0.50.50.50.5-0.5-0.1-0.5
Bone: stiffness0.60.91.6-1.0-1.00.90.90.90.9-0.9-0.9-0.90.91.30.9
Bone: tissue strength0.10.10.20.20.2-0.3-0.1-0.3-0.40.30.40.3-0.3-0.4-0.3
Bone: trabecular number2.64.04.52.02.0-2.1-1.6-2.0-2.12.12.12.1-2.0-1.7-2.0
Bone: trabecular spacing2.43.13.2-1.8-1.81.81.71.81.7-1.8-1.7-1.81.81.71.8
Bone: trabecular thickness1.21.41.51.21.2-1.2-1.2-1.2-1.21.21.21.2-1.2-1.0-1.2
Bone: trabecular tissue density1.31.92.1-1.4-1.41.41.01.41.4-1.4-1.4-1.41.41.31.4
Breakpoint value in progressive ratio session0.10.10.2-0.2-0.20.4-0.20.20.3-0.4-0.3-0.40.20.50.2
Distance traveled before self-admin1.11.11.6-1.1-1.11.10.81.01.2-1.1-1.2-1.11.01.31.0
Distance traveled after self-admin2.22.53.5-1.6-1.61.51.81.61.4-1.5-1.4-1.51.61.91.6
Delta time in closed arm before/after self-admin2.01.92.01.41.4-1.4-1.3-1.4-1.41.41.41.4-1.4-1.3-1.4
Delta time in open arm before/after self-admin0.10.10.20.30.3-0.30.0-0.2-0.40.30.40.3-0.2-0.4-0.2
Diff in mean of infusions in LGA sessions2.83.24.5-1.7-1.71.90.81.72.0-1.9-2.0-1.91.72.11.7
Extinction: sum of active levers before priming2.62.63.21.61.6-1.6-1.3-1.6-1.81.61.81.6-1.6-1.4-1.6
Active lever presses in extinction session 60.40.31.60.70.7-0.3-1.2-0.6-0.40.30.40.3-0.5-0.4-0.5
Delta distance traveled before/after self-admin2.32.43.7-1.6-1.61.51.91.61.3-1.5-1.3-1.51.61.61.6
Delta ambulatory time before/after self-admin2.12.33.7-1.5-1.51.41.91.61.3-1.4-1.3-1.41.61.51.6
Time in closed arm before self-admin1.72.02.6-1.5-1.51.41.61.51.4-1.4-1.4-1.41.41.11.4
Time in closed arm after self-admin0.60.60.8-0.8-0.80.70.90.80.8-0.7-0.8-0.70.80.60.8
Time in open arm before self-admin0.20.20.4-0.4-0.40.5-0.10.30.6-0.5-0.6-0.50.40.70.4
Time in open arm after self-admin0.10.10.10.40.4-0.3-0.3-0.3-0.40.30.40.3-0.3-0.3-0.3
Sum of active levers in priming session hrs 5-60.10.10.30.20.2-0.1-0.6-0.2-0.10.10.10.1-0.20.2-0.2
Time to tail flick, vehicle, before self-admin0.80.81.40.90.9-0.8-1.2-1.0-0.80.80.80.8-0.9-0.7-0.9
Time to tail flick, vehicle, after self-admin2.02.12.9-1.4-1.41.60.81.41.7-1.5-1.7-1.51.41.31.4
Time to tail flick, test, before self-admin0.90.81.51.01.0-0.9-1.2-1.0-0.90.90.90.9-1.0-0.6-1.0
Time to tail flick, test, after self-admin3.33.33.51.81.8-1.9-1.6-1.9-1.81.91.81.9-1.9-1.8-1.9
Delta time to tail flick, vehicle, before/after SA0.40.30.4-0.6-0.60.60.60.60.7-0.6-0.7-0.60.60.30.6
Delta time to tail flick, test, before/after SA0.30.30.70.50.5-0.6-0.1-0.5-0.50.60.50.6-0.5-0.8-0.5
Ambulatory time before self-admin0.60.70.9-0.8-0.80.90.50.80.9-0.9-0.9-0.90.81.00.8
Ambulatory time after self-admin3.64.05.3-2.0-2.01.92.32.01.8-1.9-1.8-1.92.02.12.0
Total heroin consumption0.30.40.4-0.6-0.60.60.30.60.6-0.6-0.6-0.60.60.70.6
Area under the delay curve0.00.00.1-0.1-0.10.20.00.20.3-0.2-0.3-0.20.20.20.2
Delay disc. indifference point, 0s delay0.30.30.50.60.6-0.5-0.7-0.6-0.60.50.60.5-0.6-0.5-0.6
Delay disc. indifference point, 16s delay0.20.20.30.50.5-0.4-0.6-0.5-0.40.40.40.4-0.5-0.4-0.5
Delay disc. indifference point, 2s delay1.51.61.8-1.3-1.31.31.11.31.3-1.3-1.3-1.31.31.31.3
Delay disc. indifference point, 24s delay0.20.20.3-0.4-0.40.50.20.50.5-0.5-0.5-0.50.50.50.5
Delay disc. indifference point, 4s delay1.61.72.0-1.2-1.21.31.11.31.4-1.3-1.4-1.31.31.31.3
Delay disc. indifference point, 8s delay0.00.00.00.20.2-0.1-0.2-0.1-0.00.10.00.1-0.1-0.1-0.1
Delay discount exponential model param0.20.30.40.40.4-0.5-0.3-0.5-0.60.50.60.5-0.5-0.5-0.5
Delay discount hyperbolic model param0.60.60.80.70.7-0.8-0.6-0.8-0.90.80.90.8-0.8-0.8-0.8
Fecal boli incidents, locomotor time 10.80.91.0-1.0-1.01.00.91.00.9-1.0-0.9-1.01.00.71.0
Change in fecal boli incidents, locomotor task0.10.10.2-0.3-0.30.30.10.30.4-0.3-0.4-0.30.30.30.3
Time >=10cm from walls, locomotor time 10.80.81.51.01.0-0.8-1.2-0.9-0.70.80.70.8-0.9-1.0-0.9
Bouts of movement, locomotor time 15.05.55.8-2.4-2.42.42.12.42.4-2.3-2.4-2.32.42.22.4
Total resting periods, locomotor time 14.95.55.7-2.4-2.42.42.12.42.4-2.4-2.4-2.42.42.22.4
Rest time, locomotor task time 13.23.43.8-1.9-1.91.91.51.92.0-1.9-2.0-1.91.91.71.9
Distance moved, locomotor task time 13.13.43.71.91.9-1.9-1.5-1.8-1.91.91.91.9-1.8-1.7-1.8
Vertical activity count, locomotor time 11.11.21.21.11.1-1.1-1.0-1.1-1.11.11.11.1-1.1-1.0-1.1
Time >=10cm from walls, locomotor time 20.30.40.4-0.6-0.60.60.60.60.6-0.6-0.6-0.60.60.50.6
Bouts of movement, locomotor time 23.74.04.5-2.1-2.11.92.02.02.0-1.9-2.0-1.92.01.82.0
Total resting periods, locomotor time 24.24.55.0-2.2-2.22.12.12.12.1-2.1-2.1-2.12.12.02.1
Rest time, locomotor task time 20.91.11.2-1.1-1.11.10.81.01.1-1.0-1.1-1.01.01.01.0
Distance moved, locomotor task time 22.73.13.71.81.8-1.8-1.3-1.7-1.91.81.91.8-1.8-1.6-1.8
Vertical activity count, locomotor time 20.30.40.50.70.7-0.6-0.5-0.6-0.60.60.60.6-0.6-0.3-0.6
Weight adjusted by age1.82.02.3-1.4-1.41.51.11.41.5-1.5-1.5-1.51.41.41.4
Seeking ratio, delayed vs. immediate footshock1.21.31.71.01.0-1.3-0.6-1.1-1.31.31.31.3-1.1-1.3-1.1
Locomotion in novel chamber0.20.20.40.40.4-0.4-0.3-0.4-0.50.40.50.4-0.4-0.7-0.4
Locomotion in novel chamber post-restriction0.60.70.9-0.9-0.90.80.90.90.8-0.8-0.8-0.80.90.70.9
Progressive ratio0.10.10.30.40.4-0.3-0.5-0.4-0.30.30.30.3-0.4-0.5-0.4
Food seeking constrained by brief footshock1.31.61.7-1.3-1.31.31.01.31.3-1.3-1.3-1.31.31.01.3
Seeking ratio, punishment vs. effort0.91.11.2-1.1-1.11.01.11.11.0-1.0-1.0-1.01.11.11.1
Run reversals in cocaine runway, females3.73.74.12.02.0-2.0-1.8-2.0-2.02.02.02.0-2.0-1.3-2.0
Run reversals in cocaine runway, males2.42.32.4-1.5-1.51.51.41.51.5-1.5-1.5-1.51.51.51.5
Latency to leave start box in cocaine runway0.60.61.0-0.8-0.80.80.70.80.8-0.8-0.8-0.80.81.00.8
Latency to leave start box in cocaine runway, F1.51.62.5-1.2-1.21.31.11.21.2-1.3-1.2-1.31.31.61.3
Latency to leave start box in cocaine runway, M1.31.21.31.11.1-1.1-1.0-1.1-1.11.11.11.1-1.1-1.1-1.1
Cd content in liver0.30.30.70.60.6-0.5-0.8-0.6-0.40.50.40.5-0.6-0.5-0.6
Co content in liver3.84.54.7-2.1-2.12.21.92.12.1-2.2-2.1-2.22.12.12.1
Cu content in liver0.50.60.7-0.8-0.80.90.50.80.9-0.9-0.9-0.90.80.80.8
Fe content in liver2.12.52.71.61.6-1.6-1.4-1.6-1.61.61.61.6-1.6-1.6-1.6
K content in liver0.60.60.80.80.8-0.7-0.9-0.8-0.70.70.70.7-0.8-0.7-0.8
Mg content in liver1.21.31.51.11.1-1.1-1.2-1.1-1.11.11.11.1-1.1-1.1-1.1
Mn content in liver2.02.32.41.51.5-1.5-1.4-1.5-1.51.51.51.5-1.5-1.5-1.5
Na content in liver0.70.70.8-0.8-0.80.90.50.80.9-0.9-0.9-0.90.80.90.8
Rb content in liver0.30.30.40.50.5-0.6-0.3-0.6-0.60.60.60.6-0.6-0.6-0.6
Se content in liver0.91.11.11.01.0-1.1-1.0-1.1-1.01.11.01.1-1.1-1.0-1.1
Sr content in liver0.40.40.60.70.7-0.6-0.8-0.7-0.60.60.60.6-0.6-0.7-0.6
Zn content in liver1.01.11.2-1.0-1.01.10.71.01.1-1.1-1.1-1.11.01.11.0