Hub : Genes

Tpm2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000114391 0.04 0.04 6.4e-03 0.02 0.01 0.01 0.01 4.5e-03 2.1e-02 8.8e-03 1.7e-02
2 Adipose gene expression ENSRNOG00000016731 0.07 0.07 3.4e-03 0 0.01 0.01 0.01 2.2e-01 2.7e-02 2.1e-02 4.7e-02
3 Adipose isoform ratio ENSRNOT00000114391 0.06 0.07 8.0e-03 0 0.01 0.01 0 1.1e-01 4.9e-02 9.7e-03 1.2e-01
4 BLA alternative polyA ENSRNOT00000114391 0.13 0.08 3.6e-07 0.15 0.11 0.12 0.14 1.8e-08 2.0e-06 4.3e-07 7.1e-08
5 BLA gene expression ENSRNOG00000016731 0.25 0.15 4.6e-12 0.2 0.18 0.17 0.17 1.0e-10 3.6e-10 3.4e-09 1.1e-09
6 BLA isoform ratio ENSRNOT00000022801 0.12 0.07 9.5e-06 0.05 0.09 0.08 0.07 1.3e-03 1.9e-05 4.9e-05 8.5e-05
7 BLA isoform ratio ENSRNOT00000114391 0.19 0.1 1.8e-10 0.14 0.16 0.15 0.16 6.9e-08 5.0e-09 2.8e-08 8.3e-09
8 Brain alternative polyA ENSRNOT00000114391 0.07 0.05 7.3e-05 0.03 0.03 0.03 0.03 1.3e-03 7.3e-04 1.7e-03 1.2e-03
9 Brain gene expression ENSRNOG00000016731 0.09 0.06 3.3e-07 0.07 0.07 0.07 0.07 5.9e-07 3.9e-07 9.5e-07 4.9e-07
10 Brain isoform ratio ENSRNOT00000114391 0.04 0.03 1.2e-03 0.03 0.01 0.02 0.03 9.6e-04 1.3e-02 1.1e-02 2.1e-03
11 Liver alternative polyA ENSRNOT00000114391 0.1 0.06 5.8e-07 0.04 0.04 0.03 0.04 1.4e-05 1.8e-05 1.1e-04 4.2e-05
12 Liver gene expression ENSRNOG00000016731 0.08 0.05 2.5e-05 0.04 0.04 0.04 0.04 2.3e-05 2.9e-05 4.9e-05 5.0e-05
13 Liver isoform ratio ENSRNOT00000114391 0.05 0.03 7.7e-04 0 0.01 0 0 1.1e-01 3.7e-02 7.8e-02 1.1e-01
14 PL gene expression ENSRNOG00000016731 0.06 0.05 1.8e-04 0.04 0.04 0.04 0.04 6.4e-04 5.6e-04 2.9e-04 5.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail2.27.113.3-0.9-1.23.2-3.73.72.9-3.3-2.93.0-3.1-0.90.91.43.1
BMI without tail4.18.514.40.7-2.33.2-2.82.83.8-3.3-3.53.7-3.60.7-0.72.73.7
Body weight2.711.518.60.5-2.74.3-3.93.94.2-3.9-3.84.1-3.80.5-0.53.13.9
Epididymis fat weight0.30.71.30.5-0.70.6-0.20.21.1-0.7-1.01.1-1.10.5-0.50.91.1
Glucose0.91.42.30.4-1.11.4-1.21.21.5-1.3-1.31.4-1.30.4-0.41.21.4
Heart weight0.50.71.20.7-1.00.8-0.50.51.1-0.7-0.91.0-0.80.7-0.71.00.9
Left kidney weight0.51.53.21.3-1.81.5-0.70.71.5-0.7-0.71.1-0.81.3-1.31.80.9
Right kidney weight0.10.31.01.0-0.5-0.30.7-0.70.20.3-0.00.10.11.0-1.00.5-0.0
Tail length1.54.78.91.2-1.91.9-1.21.23.0-2.2-2.83.0-2.71.2-1.22.32.8
Length with tail0.62.24.21.4-1.91.5-0.60.62.0-1.1-1.51.7-1.31.4-1.42.01.5
Length without tail0.30.61.40.3-0.1-0.30.5-0.5-0.81.01.2-1.01.20.3-0.3-0.1-1.2
Liver weight, left0.20.41.10.10.3-0.50.6-0.60.5-0.4-1.00.9-1.00.1-0.10.11.1
Liver weight, right0.20.31.20.40.2-0.91.1-1.1-0.30.70.3-0.30.30.4-0.4-0.0-0.3
Parametrial fat weight0.10.30.50.6-0.60.30.1-0.10.6-0.2-0.40.5-0.50.6-0.60.70.6
Retroperitoneal fat weight0.10.40.9-0.70.9-0.80.6-0.6-0.70.40.3-0.50.5-0.70.7-0.9-0.4
Intraocular pressure2.02.85.01.1-2.02.2-1.51.52.2-1.5-1.41.8-1.51.1-1.12.21.5
Extensor digitorum longus weight3.313.222.20.6-2.94.4-3.83.84.7-4.2-4.24.6-4.30.6-0.63.44.4
Soleus weight1.13.17.62.8-1.5-0.82.3-2.30.11.50.9-0.50.92.8-2.81.6-0.8
Tibialis anterior weight4.616.028.81.6-3.74.6-3.43.45.4-4.2-4.65.1-4.71.6-1.64.34.8
Tibia length0.51.53.81.8-0.7-1.11.9-1.9-0.01.10.4-0.30.41.8-1.80.8-0.3
Number of licking bursts3.33.97.0-0.5-0.82.1-2.22.22.3-2.5-2.52.5-2.6-0.50.51.12.6
Food consumed during 24 hour testing period0.50.61.10.7-0.80.6-0.30.31.0-0.6-0.91.0-0.90.7-0.70.91.0
Times rat made contact with spout0.50.61.5-0.80.00.9-1.21.20.5-0.9-0.70.6-0.7-0.80.8-0.00.8
Mean time between licks in bursts0.91.34.2-0.31.3-2.01.9-1.9-1.21.00.5-0.70.6-0.30.3-1.2-0.7
Mean num. licks in bursts1.41.73.2-0.20.9-1.31.2-1.2-1.71.61.7-1.81.7-0.20.2-1.1-1.7
Std. dev. time between licks in bursts0.40.51.2-0.20.8-1.11.0-1.0-0.80.70.5-0.70.6-0.20.2-0.8-0.7
Water consumed over 24 hours0.70.91.8-0.2-0.61.3-1.31.31.0-1.1-0.91.0-1.0-0.20.20.61.1
Indifference point 0 sec2.33.710.42.7-3.22.3-0.90.91.50.10.50.30.42.7-2.73.0-0.2
Indifference point AUC5.97.011.90.7-2.33.2-2.62.63.4-3.0-3.23.4-3.00.7-0.72.53.1
Indifference point function ln k1.92.64.5-0.11.1-1.71.7-1.7-2.02.02.1-2.12.0-0.10.1-1.2-2.0
Indifference point function log k1.92.64.5-0.11.1-1.71.7-1.7-2.02.02.1-2.12.0-0.10.1-1.2-2.0
Delay discounting total patch changes 0 sec2.43.910.92.6-3.32.6-1.41.41.8-0.40.10.7-0.02.6-2.63.10.2
Delay discounting total patch changes 12 sec2.53.37.30.3-1.72.7-2.52.52.1-2.0-1.51.8-1.70.3-0.31.71.7
Delay discounting total patch changes 18 sec0.71.01.70.8-1.31.3-0.90.91.2-0.8-0.81.0-0.90.8-0.81.30.8
Delay discounting total patch changes 24 sec2.73.47.21.1-2.32.7-2.02.02.3-1.7-1.41.8-1.41.1-1.12.41.5
Delay discounting total patch changes 6 sec3.45.210.72.0-3.23.3-2.22.22.8-1.7-1.42.0-1.42.0-2.03.21.5
Delay discounting time to switch 0 sec2.84.27.8-1.32.5-2.82.0-2.0-2.61.91.8-2.21.9-1.31.3-2.6-1.9
Delay discounting water rate 0 sec2.64.210.01.5-2.83.2-2.22.22.4-1.5-1.01.6-1.31.5-1.52.81.4
Delay discounting water rate 12 sec0.20.20.60.7-0.80.5-0.10.10.30.10.2-0.0-0.10.7-0.70.80.1
Delay discounting water rate 18 sec0.70.92.6-0.5-0.51.5-1.61.60.8-1.1-0.60.7-0.8-0.50.50.50.8
Delay discounting water rate 24 sec0.50.71.8-1.40.70.5-1.21.2-0.1-0.7-0.30.1-0.5-1.41.4-0.70.4
Delay discounting water rate 6 sec0.40.61.00.3-0.70.9-0.70.71.0-0.8-0.70.8-0.90.3-0.30.91.0
Locomotor activity0.00.00.00.00.0-0.10.1-0.10.0-0.0-0.10.1-0.10.0-0.0-0.00.1
Locomotor testing distance0.30.51.41.2-0.7-0.30.9-0.9-0.00.70.4-0.30.51.2-1.20.6-0.4
Locomotor testing rearing0.40.61.00.8-0.90.5-0.20.21.0-0.5-0.80.9-0.80.8-0.81.00.9
Light reinforcement 11.93.59.63.1-2.60.70.9-0.91.50.3-0.20.8-0.23.1-3.12.70.6
Light reinforcement 23.04.011.63.4-2.60.41.4-1.41.01.00.50.10.63.4-3.42.6-0.4
Reaction time number correct0.20.30.80.8-0.90.6-0.30.30.5-0.1-0.00.2-0.20.8-0.80.90.1
Reaction time mean minus median2.12.76.5-2.62.0-0.3-1.01.00.1-1.5-1.61.1-1.5-2.62.6-1.71.3
Reaction time mean minus median AUC1.72.23.5-1.81.10.4-1.21.20.7-1.7-1.91.5-1.8-1.81.8-0.91.6
Reaction time num false alarms0.20.20.6-0.80.6-0.1-0.20.2-0.1-0.4-0.50.3-0.2-0.80.8-0.60.2
Reaction time num false alarms AUC0.20.30.6-0.1-0.30.6-0.60.60.6-0.7-0.80.7-0.6-0.10.10.20.6
Reaction time trials correct on left0.20.30.80.8-0.90.6-0.30.30.5-0.1-0.00.2-0.20.8-0.80.90.1
Reaction time trials on left0.20.20.70.7-0.80.5-0.20.20.4-0.00.10.1-0.10.7-0.70.80.0
Reaction time mean2.33.28.6-2.32.9-2.31.0-1.0-1.80.60.3-1.00.4-2.32.3-2.8-0.5
Reaction time mean AUC2.63.49.0-2.43.0-2.31.0-1.0-1.90.60.4-1.10.4-2.42.4-2.9-0.6
Median of all reaction times2.94.08.2-1.62.8-2.91.9-1.9-2.51.51.3-1.81.3-1.61.6-2.7-1.4
Reaction time omissions1.41.93.7-0.71.6-1.91.7-1.7-1.71.41.1-1.41.2-0.70.7-1.5-1.2
Reaction time false alarm rate0.10.20.5-0.70.6-0.2-0.00.0-0.3-0.2-0.20.00.1-0.70.7-0.7-0.0
Reaction time premature initiation rate1.52.03.6-1.31.6-1.20.6-0.6-1.91.11.6-1.81.6-1.31.3-1.8-1.4
Reaction time premature initiations0.71.12.1-0.80.9-0.70.3-0.3-1.40.91.4-1.51.3-0.80.8-1.2-1.2
Std. dev. reaction times1.92.66.7-2.62.6-1.30.0-0.0-0.8-0.6-0.80.2-0.7-2.62.6-2.30.6
Reaction time trials completed0.20.20.70.7-0.80.5-0.20.20.4-0.00.10.1-0.10.7-0.70.80.0
Reaction time trials AUC0.20.20.60.7-0.80.5-0.30.30.4-0.00.10.1-0.10.7-0.70.80.1
Social response proportion2.83.07.5-1.22.4-2.72.0-2.0-2.11.41.0-1.51.2-1.21.2-2.3-1.2
Social responses0.30.41.1-0.0-0.10.1-0.30.30.7-0.8-1.11.0-0.9-0.00.00.21.0
Social time0.91.14.10.11.1-2.02.0-2.0-0.70.90.1-0.30.40.1-0.1-0.8-0.2
Conditioned locomotion0.60.71.81.3-1.30.60.1-0.10.20.50.7-0.40.61.3-1.31.1-0.5
Cocaine response after cond. corrected2.32.53.91.8-0.7-1.01.7-1.7-1.12.02.0-1.71.91.8-1.80.4-1.8
Cocaine response after cond. not corrected2.52.84.32.1-0.8-1.32.0-2.0-0.92.01.7-1.51.72.1-2.10.5-1.6
Cocaine response before conditioning0.40.51.4-0.2-0.00.3-0.30.30.8-0.9-1.21.1-1.2-0.20.20.31.2
Saline control response1.01.32.81.6-1.70.9-0.20.21.2-0.4-0.50.8-0.71.6-1.61.70.8
Condit. Reinf. active minus inactive responses0.60.71.2-0.2-0.40.9-1.11.10.9-1.1-1.01.0-1.0-0.20.20.41.0
Condit. Reinf. active-inactive response ratio0.30.30.8-0.50.10.5-0.90.90.3-0.7-0.50.4-0.5-0.50.5-0.10.4
Condit. Reinf. active responses1.62.23.90.1-0.91.6-1.61.61.9-1.8-1.92.0-1.90.1-0.11.11.9
Condit. Reinf. inactive responses2.02.54.9-0.5-0.41.4-1.61.61.8-2.0-2.22.1-2.2-0.50.50.72.2
Condit. Reinf. lever presses1.92.75.0-1.10.11.3-1.81.81.6-2.2-2.22.1-2.2-1.11.10.22.1
Condit. Reinf. lever reinforcers received1.82.64.60.1-0.91.6-1.71.72.0-2.0-2.12.1-2.10.1-0.11.22.1
Pavlov. Cond. lever latency2.23.05.81.2-0.1-1.31.8-1.8-1.72.32.4-2.22.31.2-1.2-0.2-2.3
Pavlov. Cond. magazine entry latency0.70.82.2-0.61.2-1.51.1-1.1-1.00.70.3-0.60.4-0.60.6-1.2-0.5
Pavlov. Cond. change in total contacts1.41.93.7-1.91.4-0.0-0.90.90.4-1.5-1.71.2-1.6-1.91.9-1.11.5
Pavlov. Cond. index score0.60.81.8-1.31.1-0.3-0.30.30.0-0.8-1.00.6-0.9-1.31.3-1.00.8
Pavlov. Cond. latency score0.81.02.2-1.51.1-0.0-0.70.70.2-1.0-1.10.8-1.1-1.51.5-0.91.0
Pavlov. Cond. lever contacts1.11.53.1-0.80.00.9-1.21.21.2-1.6-1.81.6-1.6-0.80.80.21.6
Pavlov. Cond. magazine entry number0.81.02.71.6-1.50.60.1-0.10.40.50.7-0.30.71.6-1.61.4-0.5
Pavlov. Cond. intertrial magazine entries0.50.71.40.5-1.01.2-1.11.11.0-0.8-0.60.7-0.60.5-0.51.00.6
Pavlov. Cond. lever-magazine prob. diff.0.70.92.0-1.41.2-0.4-0.30.30.0-0.8-1.00.6-0.9-1.41.4-1.10.8
Pavlov. Cond. response bias0.60.81.6-1.00.60.2-0.60.60.5-1.1-1.31.0-1.2-1.01.0-0.41.1
Conditioned reinforcement - actives0.40.41.8-0.2-0.41.0-1.31.30.5-0.7-0.30.4-0.2-0.20.20.40.2
Conditioned reinforcement - inactives0.10.10.20.3-0.30.3-0.30.3-0.10.20.4-0.30.30.3-0.30.2-0.4
Conditioned locomotion0.70.92.90.3-1.01.6-1.71.70.8-0.8-0.30.5-0.30.3-0.30.80.4
Intermittent access intake day 1-15 change1.11.11.7-1.30.70.4-1.21.20.5-1.2-1.20.9-1.1-1.31.3-0.61.2
Intermittent access intake escalation1.31.32.1-1.10.30.9-1.41.40.8-1.4-1.41.2-1.3-1.11.1-0.21.4
Intermittent access intake escalation 22.01.92.9-1.60.70.8-1.71.70.7-1.7-1.51.2-1.6-1.61.6-0.61.6
Intermitt. access day 1 inactive lever presses0.60.71.40.2-0.81.2-1.01.01.0-0.9-0.80.9-0.90.2-0.20.81.0
Intermitt. access day 15 inactive lever presses0.20.30.80.7-0.90.7-0.10.10.30.10.2-0.00.20.7-0.70.8-0.1
Intermitt. access escalation Index0.90.81.71.0-1.21.0-0.40.41.2-0.6-0.70.9-0.81.0-1.01.30.9
Intermittent access day 1 total infusions0.91.01.81.3-1.30.7-0.10.1-0.10.81.2-0.81.21.3-1.31.0-1.2
Intermittent access day 15 total infusions0.80.92.70.1-1.01.6-1.61.60.9-0.9-0.50.7-0.50.1-0.10.80.5
Intermittent access terminal intake (last 3 days)1.11.23.50.3-1.21.9-1.81.81.1-1.0-0.50.8-0.60.3-0.31.00.6
Intermittent access total infusions1.41.54.50.6-1.62.1-1.91.91.2-1.0-0.50.8-0.50.6-0.61.40.5
Intermittent access day 1 locomotion0.90.92.11.0-1.00.4-0.10.1-0.50.91.3-1.01.51.0-1.00.6-1.4
Intermittent access day 15 total locomotion0.50.51.40.3-0.50.5-0.50.5-0.50.61.2-1.01.20.3-0.30.1-1.1
Intermittent access total locomotion0.30.41.0-0.2-0.20.7-1.01.0-0.40.20.8-0.70.9-0.20.2-0.1-0.8
Intermittent access standard deviation0.40.40.8-0.5-0.10.8-0.90.90.5-0.8-0.60.6-0.8-0.50.50.10.7
Cocaine induced anxiety0.91.11.80.10.6-1.21.2-1.2-1.31.31.3-1.31.20.1-0.1-0.7-1.3
Post-drug Anxiety0.20.20.40.3-0.1-0.20.5-0.50.4-0.1-0.60.5-0.70.3-0.30.30.5
Baseline Anxiety1.21.23.0-0.60.20.5-1.01.01.1-1.5-1.71.6-1.6-0.60.60.11.6
Lifetime Intake1.82.05.11.5-2.32.2-1.61.61.3-0.6-0.10.6-0.21.5-1.52.00.2
Incentive Sensitization - Responses0.20.20.50.7-0.70.30.0-0.00.00.40.5-0.30.40.7-0.70.6-0.4
Incentive Sensitization - Breakpoint0.20.20.50.7-0.60.20.1-0.1-0.10.50.6-0.40.50.7-0.70.5-0.5
Progressive ratio test 1 active lever presses1.61.64.41.4-2.12.0-1.41.40.9-0.20.50.10.41.4-1.41.8-0.3
Progressive ratio test 1 breakpoint1.61.74.41.4-2.12.0-1.51.51.0-0.30.30.20.21.4-1.41.8-0.1
Progressive ratio test 1 inactive lever presses2.02.15.82.2-2.41.5-0.50.51.10.10.40.20.42.2-2.22.2-0.1
Progressive ratio test 2 active lever presses1.11.12.91.5-1.71.2-0.60.60.40.40.8-0.30.71.5-1.51.4-0.7
Progressive ratio test 2 breakpoint1.01.12.51.5-1.61.0-0.50.50.20.51.0-0.50.91.5-1.51.2-0.9
Progressive ratio test 2 inactive lever presses0.40.51.40.6-1.11.2-1.01.00.6-0.4-0.10.3-0.10.6-0.60.90.1
Total sessions with >9 infusions1.61.84.32.0-2.11.1-0.20.20.50.60.9-0.41.02.0-2.01.8-0.8
Short access day 1 total inactive lever presses2.32.66.21.2-2.22.5-2.02.01.8-1.3-0.81.2-0.91.2-1.22.11.1
Short access day 10 total inactive lever presses0.10.10.4-0.1-0.20.4-0.20.20.4-0.4-0.50.5-0.6-0.10.10.20.6
Short access day 1 total infusions2.52.77.52.2-2.72.1-1.01.01.5-0.3-0.00.6-0.12.2-2.22.50.2
Short access day 10 total infusions1.61.84.91.8-2.21.7-1.01.01.2-0.30.10.40.01.8-1.82.00.0
Short access total infusions1.82.05.42.1-2.31.5-0.60.60.80.20.6-0.00.52.1-2.12.0-0.4
Short access day 1 locomotion0.60.61.41.2-1.00.3-0.30.3-0.10.50.8-0.60.91.2-1.20.7-0.8
Short access day 10 total locomotion0.40.51.0-0.70.8-0.6-0.10.1-0.90.40.6-0.70.7-0.70.7-1.0-0.7
Short access total locomotion0.50.51.41.1-1.20.7-0.40.40.40.10.3-0.10.31.1-1.11.0-0.3
Compulsive drug intake0.20.20.50.2-0.40.5-0.30.30.7-0.5-0.60.7-0.30.2-0.20.50.4
One hour access (0.3 mA shock)1.01.12.71.0-1.71.6-1.11.11.1-0.6-0.30.7-0.21.0-1.01.50.2
One hour access (shock baseline)1.11.33.61.2-1.91.8-1.21.21.0-0.30.10.3-0.01.2-1.21.60.1
Number of responses in last shaping day2.12.16.12.5-2.10.70.4-0.40.70.70.7-0.10.72.5-2.51.9-0.4
Context. condit. distance diff. score0.10.10.1-0.40.20.1-0.20.2-0.30.10.3-0.30.3-0.40.4-0.3-0.3
Locomotion velocity, session 13.74.011.73.4-3.01.00.5-0.51.30.60.50.20.43.4-3.42.9-0.2
Locomotion distance, session 11.01.33.71.9-1.70.60.3-0.30.90.2-0.00.40.01.9-1.91.60.2
Locomotion velocity, session 21.82.13.9-0.6-0.41.4-1.61.61.6-1.9-2.01.9-1.8-0.60.60.61.8
Locomotion distance, session 21.21.83.01.4-1.50.8-0.10.11.7-0.9-1.51.7-1.41.4-1.41.71.5
Locomotion velocity, session 30.80.92.71.6-1.30.20.5-0.50.40.50.4-0.00.31.6-1.61.2-0.2
Locomotion distance, session 32.42.65.21.2-2.12.3-1.61.62.0-1.3-1.11.5-1.31.2-1.22.11.4
Stereotopy head waving bouts, day 30.91.12.51.6-0.8-0.51.3-1.3-0.11.10.8-0.50.81.6-1.60.8-0.6
Stereotopy head waving duration, day 30.60.71.50.9-0.2-0.81.2-1.2-0.51.10.9-0.70.90.9-0.90.2-0.8
Locomotion velocity, session 70.00.00.1-0.10.1-0.20.1-0.1-0.30.20.2-0.30.3-0.10.1-0.2-0.2
Locomotion distance, session 70.20.30.60.5-0.80.7-0.50.50.6-0.4-0.30.5-0.40.5-0.50.70.4
Stereotopy head waving bouts, day 71.92.13.90.7-1.62.0-1.51.51.9-1.4-1.31.6-1.40.7-0.71.71.5
Stereotopy head waving duration, day 70.40.51.00.7-0.90.6-0.20.20.9-0.5-0.60.8-0.70.7-0.71.00.7
Locomotion velocity, session 80.60.71.71.3-0.5-0.71.3-1.30.10.70.1-0.00.21.3-1.30.6-0.1
Locomotion distance, session 80.40.51.51.2-1.00.20.4-0.40.60.1-0.20.4-0.11.2-1.21.00.2
Degree of sensitization distance1.21.22.8-0.51.3-1.71.4-1.4-1.41.10.8-1.10.9-0.50.5-1.3-1.0
Degree of sensitization stereotypy1.31.42.90.3-1.11.7-1.51.51.5-1.3-1.01.2-1.20.3-0.31.21.2
Condit. Reinf. active minus inactive responses0.30.40.9-0.40.00.4-0.50.50.6-0.8-1.00.9-0.9-0.40.40.10.9
Condit. Reinf. active-inactive response ratio0.50.61.0-0.61.0-1.00.6-0.6-1.00.70.7-0.80.5-0.60.6-1.0-0.6
Condit. Reinf. active responses1.92.34.9-0.5-0.41.4-1.51.51.8-2.0-2.22.1-2.0-0.50.50.72.1
Condit. Reinf. inactive responses2.42.86.2-0.8-0.21.3-1.51.51.9-2.2-2.52.4-2.3-0.80.80.52.3
Incentive salience index mean2.93.56.50.2-1.32.0-1.81.82.4-2.3-2.52.5-2.30.2-0.21.52.4
Condit. Reinf. lever presses7.29.617.21.4-2.93.4-2.82.84.1-3.4-3.74.0-3.41.4-1.43.23.6
Time in familiar zone, hab. session 12.32.16.4-2.51.8-0.0-1.21.2-0.8-0.7-0.2-0.2-0.3-2.52.5-1.90.1
Time in novel zone, hab. session 14.14.08.82.3-0.6-1.93.0-3.0-1.12.41.7-1.51.92.3-2.30.5-1.8
Total zone transitions, hab. session 10.00.00.1-0.10.2-0.30.2-0.2-0.0-0.0-0.20.1-0.2-0.10.1-0.10.1
Total locomotion distance, hab. session 10.71.12.0-1.41.00.1-0.70.70.4-1.1-1.20.9-1.1-1.41.4-0.81.1
Locomotion velocity, hab. session 11.31.94.0-1.10.30.8-1.31.31.2-1.8-2.01.8-1.8-1.11.1-0.11.8
Time in familiar zone, hab. session 21.31.43.5-1.71.9-1.10.2-0.2-1.10.20.2-0.60.2-1.71.7-1.8-0.4
Time in novel zone, hab. session 22.12.13.11.8-0.9-0.61.5-1.5-0.81.71.7-1.41.71.8-1.80.7-1.6
Total zone transitions, hab. session 20.50.61.31.1-1.10.5-0.10.11.0-0.4-0.60.8-0.61.1-1.11.10.7
Total locomotion distance, hab. session 20.50.61.30.0-0.40.8-0.70.71.0-1.0-1.11.1-1.00.0-0.00.61.1
Locomotion velocity, hab. session 20.70.91.8-0.1-0.51.0-1.01.01.2-1.2-1.31.3-1.2-0.10.10.61.3
Novel to familiar place preference ratio3.13.36.11.3-0.1-1.42.1-2.1-1.62.42.3-2.12.51.3-1.3-0.1-2.3
Novelty place preference3.83.97.61.10.2-1.72.2-2.2-2.02.62.6-2.52.81.1-1.1-0.5-2.6
Time in novel zone, NPP test4.74.99.11.20.3-2.02.6-2.6-2.32.92.9-2.73.01.2-1.2-0.6-2.9
Total zone transitions, NPP test0.70.91.91.4-1.30.60.1-0.11.1-0.3-0.70.9-0.61.4-1.41.40.8
Total locomotion distance, NPP test1.62.23.81.3-1.91.8-1.11.11.9-1.2-1.31.6-1.21.3-1.31.91.4
Locomotion velocity, NPP test2.02.84.81.0-1.92.1-1.61.62.2-1.6-1.71.9-1.61.0-1.02.01.7
Pavlov. Cond. lever latency5.06.411.1-0.82.1-2.72.4-2.4-3.32.83.1-3.33.0-0.80.8-2.4-3.1
Pavlov. Cond. magazine entry latency0.20.30.9-0.20.10.1-0.30.30.6-0.7-0.90.8-0.8-0.20.20.10.8
Pavlov. Cond. change in total contacts1.82.03.40.5-1.21.5-1.31.31.8-1.6-1.71.8-1.70.5-0.51.41.7
Pavlov. Cond. index score2.02.55.10.0-0.81.3-1.41.42.0-2.0-2.32.3-2.20.0-0.01.02.2
Pavlov. Cond. latency score1.92.44.70.1-0.81.4-1.51.52.0-1.9-2.12.2-2.00.1-0.11.12.1
Pavlov. Cond. lever contacts3.94.67.70.5-1.62.4-2.32.32.8-2.5-2.62.8-2.50.5-0.51.92.6
Pavlov. Cond. magazine entry number0.50.61.40.20.1-0.50.6-0.6-0.91.01.2-1.11.20.2-0.2-0.3-1.2
Pavlov. Cond. intertrial magazine entries0.10.20.4-0.2-0.10.4-0.20.20.5-0.5-0.70.6-0.6-0.20.20.20.6
Pavlov. Cond. lever-magazine prob. diff.1.92.45.0-0.3-0.51.2-1.51.51.8-2.0-2.22.2-2.1-0.30.30.82.1
Pavlov. Cond. response bias2.02.54.70.2-1.01.5-1.51.52.0-1.9-2.12.2-2.00.2-0.21.22.1
Bone: apparent density1.11.83.3-0.4-0.71.7-1.81.81.5-1.7-1.51.5-1.6-0.40.40.81.6
Bone surface0.61.11.90.5-1.21.4-1.11.11.3-1.0-0.91.1-1.10.5-0.51.21.1
Bone volume0.61.01.70.1-0.81.3-1.21.21.2-1.2-1.01.1-1.20.1-0.10.81.2
Bone: connectivity density0.71.12.4-0.6-0.31.3-1.61.61.0-1.3-1.11.1-1.1-0.60.60.41.1
Bone: cortical apparent density0.91.23.4-1.91.5-0.4-0.50.5-0.6-0.4-0.3-0.1-0.4-1.91.9-1.50.3
Bone: cortical area1.72.65.0-0.8-0.31.5-1.71.71.7-2.1-2.12.0-2.2-0.80.80.52.2
Bone: cortical porosity0.30.30.6-0.10.4-0.60.6-0.6-0.70.60.7-0.70.7-0.10.1-0.5-0.8
Bone: cortical porosity0.00.00.10.0-0.20.3-0.20.20.1-0.00.1-0.00.10.0-0.00.2-0.2
Bone: cortical thickness1.11.82.8-1.50.41.2-1.71.70.8-1.6-1.41.2-1.6-1.51.5-0.31.5
Bone: cortical thickness0.20.30.7-0.80.8-0.50.3-0.3-0.50.10.1-0.3-0.1-0.80.8-0.8-0.0
Bone: cortical tissue density0.81.03.0-1.71.5-0.4-0.30.3-0.6-0.3-0.2-0.2-0.3-1.71.7-1.40.2
Bone: elastic displacement2.93.36.1-1.42.0-1.71.1-1.1-2.51.72.1-2.31.9-1.41.4-2.2-2.1
Bone: elastic work2.53.37.5-2.72.6-1.2-0.00.0-1.90.40.8-1.30.7-2.72.7-2.7-0.9
Bone: endosteal estimation0.71.52.61.2-1.41.0-0.40.41.6-0.9-1.31.5-1.21.2-1.21.61.3
Bone: endosteal perimeter0.91.83.61.5-1.81.2-0.50.51.7-0.9-1.21.4-1.11.5-1.51.91.2
Bone: final force0.71.12.7-0.0-0.30.6-0.70.71.3-1.3-1.61.5-1.6-0.00.00.51.6
Bone: final moment0.50.82.3-0.30.00.3-0.50.51.0-1.1-1.51.3-1.5-0.30.30.21.5
Bone: marrow area0.71.52.71.0-1.31.1-0.60.61.6-1.1-1.41.6-1.31.0-1.01.51.4
Bone: maximum diameter1.42.65.1-0.1-0.81.5-1.41.42.0-2.0-2.22.2-2.2-0.10.11.12.2
Bone: maximum force1.72.96.4-0.2-0.61.3-1.41.42.1-2.2-2.52.4-2.5-0.20.20.92.5
Bone: maximum moment1.32.35.3-0.5-0.31.0-1.21.21.7-2.0-2.32.1-2.3-0.50.50.52.2
Bone: minimum diameter0.00.10.2-0.50.4-0.20.0-0.0-0.2-0.1-0.1-0.0-0.0-0.50.5-0.4-0.0
Bone: periosteal estimation0.91.83.60.3-0.91.2-0.90.91.8-1.6-1.81.9-1.90.3-0.31.21.9
Bone: periosteal perimeter0.40.71.41.0-1.10.7-0.20.21.1-0.5-0.70.9-0.71.0-1.01.20.8
Bone: post-yield work0.91.22.31.1-1.20.8-0.20.21.5-0.9-1.31.5-1.21.1-1.11.41.3
Bone: stiffness2.13.38.2-0.1-0.51.0-1.11.12.2-2.2-2.92.7-2.8-0.10.10.92.8
Bone: tissue strength0.40.31.1-0.40.8-1.10.7-0.7-0.1-0.1-0.70.4-0.5-0.40.4-0.60.5
Bone: trabecular number1.11.72.9-0.7-0.21.3-1.61.61.3-1.7-1.61.5-1.6-0.70.70.41.6
Bone: trabecular spacing0.20.30.8-0.90.7-0.2-0.20.2-0.2-0.2-0.20.0-0.2-0.90.9-0.70.2
Bone: trabecular thickness0.00.10.1-0.20.3-0.20.1-0.1-0.30.20.2-0.20.3-0.20.2-0.3-0.3
Bone: trabecular tissue density1.21.74.40.3-0.50.6-0.40.41.7-1.4-2.12.0-2.00.3-0.30.92.1
Breakpoint value in progressive ratio session1.31.43.21.8-1.40.20.8-0.8-0.11.11.1-0.71.21.8-1.81.2-1.1
Distance traveled before self-admin3.23.46.01.2-2.22.3-1.31.32.5-1.7-1.82.1-1.81.2-1.22.32.0
Distance traveled after self-admin0.40.41.2-0.60.6-0.3-0.10.10.5-0.8-1.10.9-1.0-0.60.6-0.31.1
Delta time in closed arm before/after self-admin2.42.34.4-1.20.21.1-1.61.61.4-2.0-2.11.9-2.0-1.21.2-0.02.0
Delta time in open arm before/after self-admin0.60.61.00.8-0.3-0.40.9-0.9-0.51.00.9-0.80.90.8-0.80.2-0.9
Diff in mean of infusions in LGA sessions0.10.10.2-0.30.4-0.40.3-0.3-0.30.10.0-0.1-0.0-0.30.3-0.5-0.0
Extinction: sum of active levers before priming1.61.62.80.10.9-1.71.6-1.6-1.51.51.4-1.41.40.1-0.1-1.0-1.5
Active lever presses in extinction session 60.20.20.80.4-0.2-0.10.2-0.2-0.40.60.7-0.60.70.4-0.40.1-0.9
Delta distance traveled before/after self-admin1.11.23.4-0.71.5-1.81.3-1.3-1.20.80.5-0.80.7-0.70.7-1.4-0.6
Delta ambulatory time before/after self-admin2.22.46.5-0.82.0-2.61.9-1.9-1.81.31.0-1.41.1-0.80.8-1.9-1.1
Time in closed arm before self-admin1.41.63.5-0.10.7-1.10.8-0.8-1.71.51.9-1.91.6-0.10.1-0.9-1.8
Time in closed arm after self-admin0.20.20.6-0.80.7-0.3-0.10.1-0.4-0.10.1-0.20.0-0.80.8-0.7-0.1
Time in open arm before self-admin1.71.83.31.2-1.61.4-0.60.61.8-1.1-1.31.6-1.21.2-1.21.81.3
Time in open arm after self-admin1.41.53.31.3-1.81.6-0.80.81.5-0.7-0.71.1-0.71.3-1.31.80.8
Sum of active levers in priming session hrs 5-62.42.45.00.9-0.0-1.11.6-1.6-1.52.02.2-2.02.20.9-0.9-0.3-2.2
Time to tail flick, vehicle, before self-admin0.60.71.5-0.30.6-0.60.5-0.5-1.10.91.2-1.20.9-0.30.3-0.8-1.2
Time to tail flick, vehicle, after self-admin0.00.00.10.2-0.30.3-0.00.00.10.10.2-0.10.30.2-0.20.3-0.1
Time to tail flick, test, before self-admin0.40.41.0-0.4-0.20.8-1.01.00.5-0.8-0.60.6-0.6-0.40.40.20.5
Time to tail flick, test, after self-admin1.11.22.5-1.00.11.1-1.61.60.8-1.4-1.11.0-1.3-1.01.0-0.11.0
Delta time to tail flick, vehicle, before/after SA0.10.10.30.1-0.10.00.0-0.00.4-0.3-0.50.5-0.20.1-0.10.20.5
Delta time to tail flick, test, before/after SA0.10.00.1-0.30.3-0.0-0.10.1-0.20.00.2-0.20.0-0.30.3-0.3-0.1
Ambulatory time before self-admin2.93.05.91.5-2.42.3-1.21.22.2-1.3-1.41.8-1.41.5-1.52.41.5
Ambulatory time after self-admin0.10.10.20.2-0.0-0.30.4-0.40.3-0.1-0.40.4-0.20.2-0.20.20.3
Total heroin consumption0.81.01.71.3-0.8-0.20.8-0.8-0.41.11.2-0.91.31.3-1.30.7-1.1
Area under the delay curve0.60.61.00.8-0.3-0.40.9-0.9-0.51.00.9-0.81.00.8-0.80.2-0.9
Delay disc. indifference point, 0s delay1.31.42.60.70.1-1.11.6-1.6-1.11.51.4-1.31.50.7-0.7-0.2-1.5
Delay disc. indifference point, 16s delay1.61.62.51.5-0.9-0.31.2-1.2-0.71.51.6-1.31.51.5-1.50.6-1.5
Delay disc. indifference point, 2s delay0.10.10.3-0.60.40.1-0.50.50.0-0.3-0.30.2-0.2-0.60.6-0.30.2
Delay disc. indifference point, 24s delay0.20.20.4-0.00.4-0.60.6-0.6-0.40.40.3-0.40.3-0.00.0-0.4-0.3
Delay disc. indifference point, 4s delay0.10.10.20.10.1-0.30.4-0.4-0.30.30.3-0.30.30.1-0.1-0.1-0.3
Delay disc. indifference point, 8s delay0.00.00.00.2-0.10.00.1-0.10.10.0-0.10.2-0.10.2-0.20.10.1
Delay discount exponential model param0.40.50.7-0.80.40.3-0.80.80.4-0.9-0.80.7-0.8-0.80.8-0.20.8
Delay discount hyperbolic model param0.40.40.6-0.70.40.2-0.80.80.4-0.8-0.70.6-0.8-0.70.7-0.20.7
Fecal boli incidents, locomotor time 10.50.50.9-0.60.9-0.80.4-0.4-0.90.60.6-0.80.7-0.60.6-1.0-0.8
Change in fecal boli incidents, locomotor task1.21.22.71.2-1.61.5-0.80.81.2-0.6-0.50.8-0.61.2-1.21.60.6
Time >=10cm from walls, locomotor time 10.40.51.11.0-1.00.50.4-0.40.30.30.4-0.10.31.0-1.01.0-0.2
Bouts of movement, locomotor time 11.51.73.0-0.31.1-1.61.7-1.7-1.61.41.3-1.41.4-0.30.3-1.2-1.4
Total resting periods, locomotor time 11.92.23.5-0.81.6-1.91.7-1.7-1.91.41.3-1.61.4-0.80.8-1.7-1.5
Rest time, locomotor task time 13.03.38.6-2.52.9-2.10.8-0.8-1.90.40.3-0.90.4-2.52.5-2.9-0.6
Distance moved, locomotor task time 12.52.76.31.9-2.52.0-1.01.01.9-0.8-0.71.2-0.81.9-1.92.51.0
Vertical activity count, locomotor time 12.22.35.52.3-2.31.20.0-0.01.4-0.1-0.20.8-0.32.3-2.32.40.5
Time >=10cm from walls, locomotor time 20.10.10.10.3-0.2-0.00.3-0.30.3-0.1-0.30.3-0.20.3-0.30.30.3
Bouts of movement, locomotor time 20.30.30.70.1-0.40.6-0.40.40.8-0.7-0.80.9-0.70.1-0.10.50.7
Total resting periods, locomotor time 20.10.10.3-0.1-0.20.5-0.30.30.5-0.5-0.50.5-0.4-0.10.10.30.4
Rest time, locomotor task time 20.60.71.3-0.61.0-1.00.7-0.7-1.10.70.8-1.00.9-0.60.6-1.0-0.9
Distance moved, locomotor task time 20.40.51.1-0.60.6-0.1-0.40.40.4-0.8-1.00.8-1.0-0.60.6-0.41.0
Vertical activity count, locomotor time 20.20.30.60.5-0.3-0.10.1-0.10.7-0.4-0.70.8-0.70.5-0.50.50.8
Weight adjusted by age0.60.72.01.2-1.41.0-0.10.10.70.10.10.20.11.2-1.21.4-0.0
Seeking ratio, delayed vs. immediate footshock3.23.66.6-0.3-1.22.6-2.52.52.2-2.3-2.12.2-2.1-0.30.31.22.1
Locomotion in novel chamber0.30.30.8-0.90.7-0.1-0.60.6-0.2-0.4-0.30.1-0.2-0.90.9-0.70.1
Locomotion in novel chamber post-restriction2.02.44.0-1.60.70.7-1.71.71.0-2.0-2.01.6-2.0-1.61.6-0.51.8
Progressive ratio0.00.00.10.3-0.1-0.10.1-0.1-0.10.20.2-0.10.20.3-0.30.1-0.3
Food seeking constrained by brief footshock6.37.714.12.0-3.53.8-2.42.43.6-2.4-2.32.9-2.32.0-2.03.72.6
Seeking ratio, punishment vs. effort1.51.83.60.6-1.51.9-1.31.31.8-1.4-1.31.5-1.30.6-0.61.61.4
Run reversals in cocaine runway, females0.40.40.8-0.90.8-0.2-0.60.6-0.0-0.6-0.60.3-0.7-0.90.9-0.70.5
Run reversals in cocaine runway, males0.00.00.1-0.20.10.1-0.20.2-0.1-0.00.1-0.10.1-0.20.2-0.1-0.1
Latency to leave start box in cocaine runway0.60.71.2-0.4-0.20.9-1.11.10.8-1.0-0.90.9-1.0-0.40.40.31.0
Latency to leave start box in cocaine runway, F0.00.00.00.2-0.20.2-0.20.20.00.10.2-0.10.10.2-0.20.2-0.1
Latency to leave start box in cocaine runway, M0.90.91.60.6-1.11.2-0.70.71.3-0.9-0.91.1-1.00.6-0.61.21.1
Cd content in liver0.60.71.6-0.80.50.1-0.60.60.6-1.1-1.21.0-1.3-0.80.8-0.31.2
Co content in liver1.21.42.30.70.2-1.21.5-1.5-1.21.51.4-1.41.40.7-0.7-0.3-1.4
Cu content in liver1.31.53.4-1.11.8-1.81.2-1.2-1.50.90.7-1.10.6-1.11.1-1.7-0.7
Fe content in liver1.31.54.22.0-1.3-0.31.4-1.40.40.80.3-0.00.52.0-2.01.3-0.3
K content in liver0.50.50.70.8-0.3-0.50.8-0.8-0.40.80.7-0.60.80.8-0.80.2-0.7
Mg content in liver0.30.31.00.3-0.0-0.30.5-0.5-0.60.70.8-0.71.00.3-0.3-0.1-1.0
Mn content in liver0.30.40.7-0.80.50.1-0.60.60.2-0.7-0.70.6-0.6-0.80.8-0.50.6
Na content in liver1.92.15.3-0.11.4-2.32.2-2.2-1.61.51.1-1.31.1-0.10.1-1.3-1.1
Rb content in liver3.03.86.50.31.0-2.12.1-2.1-2.42.42.5-2.62.40.3-0.3-1.3-2.5
Se content in liver1.21.43.9-0.80.40.3-0.70.71.2-1.5-2.01.7-1.7-0.80.8-0.01.8
Sr content in liver0.30.30.8-0.1-0.10.3-0.40.40.7-0.7-0.90.9-0.6-0.10.10.20.7
Zn content in liver0.40.40.9-0.90.60.1-0.70.70.1-0.7-0.60.4-0.5-0.90.9-0.60.5