Hub : Genes

Tmc7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000016679 0.1 0.06 2.8e-04 0.09 0.07 0.06 0.07 2.4e-05 9.0e-05 2.8e-04 1.5e-04
2 Brain gene expression ENSRNOG00000016679 0.11 0.06 2.8e-08 0.06 0.07 0.07 0.07 6.1e-06 9.0e-07 8.3e-07 8.1e-07
3 Brain intron excision ratio chr1:172883314:172886548 0.06 0.04 9.7e-04 0.04 0.02 0.02 0.03 1.2e-04 7.3e-03 2.6e-03 3.6e-04
4 Brain mRNA stability ENSRNOG00000016679 0.04 0.03 5.8e-03 0.01 0 0 0 9.0e-02 9.9e-02 2.8e-01 1.1e-01
5 NAcc gene expression ENSRNOG00000016679 0.13 0.06 3.3e-09 0.12 0.11 0.12 0.11 2.3e-09 1.7e-08 6.7e-09 1.0e-08
6 OFC gene expression ENSRNOG00000016679 0.29 0.13 2.4e-04 0.14 0.11 0.11 0.11 4.3e-04 1.6e-03 1.2e-03 1.3e-03
7 PL gene expression ENSRNOG00000016679 0.25 0.12 2.7e-15 0.22 0.21 0.21 0.21 1.6e-16 6.6e-16 9.9e-16 7.5e-16
8 PL mRNA stability ENSRNOG00000016679 0.07 0.04 2.3e-05 0.07 0.05 0.06 0.06 7.9e-06 7.4e-05 5.5e-05 3.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail3.611.714.43.73.8-3.81.43.73.23.83.3
BMI without tail9.419.624.24.84.9-4.81.84.84.34.84.4
Body weight2.410.312.63.33.6-3.30.63.33.43.53.5
Epididymis fat weight0.82.02.51.51.6-1.50.71.51.31.61.4
Glucose0.40.73.8-0.7-0.30.52.0-0.7-0.0-0.60.0
Heart weight0.20.30.6-0.6-0.40.50.8-0.60.0-0.50.1
Left kidney weight3.18.811.32.93.2-2.82.42.93.42.73.3
Right kidney weight3.59.913.83.03.5-3.11.93.03.73.03.6
Tail length2.16.39.02.42.7-2.31.32.43.02.43.0
Length with tail0.20.92.00.81.0-0.70.10.81.40.81.4
Length without tail1.12.33.0-1.7-1.61.7-1.3-1.7-1.2-1.7-1.3
Liver weight, left0.30.60.90.90.8-0.90.20.90.50.90.4
Liver weight, right1.21.93.21.81.4-1.7-0.21.80.61.80.6
Parametrial fat weight2.34.55.62.02.3-2.02.12.02.42.02.3
Retroperitoneal fat weight0.20.60.80.90.9-0.90.50.90.70.90.7
Intraocular pressure0.40.50.70.80.7-0.8-0.50.80.50.80.5
Extensor digitorum longus weight3.915.521.63.94.3-3.91.13.94.54.14.7
Soleus weight1.54.48.51.62.2-1.61.81.62.91.62.9
Tibialis anterior weight5.820.030.24.24.8-4.22.64.25.44.35.5
Tibia length0.10.20.4-0.6-0.50.60.6-0.60.0-0.6-0.1
Number of licking bursts6.47.69.1-2.9-3.02.9-1.6-2.9-2.8-2.9-2.8
Food consumed during 24 hour testing period1.41.72.51.21.4-1.20.91.21.61.21.6
Times rat made contact with spout0.81.01.60.91.1-0.90.30.91.30.91.3
Mean time between licks in bursts0.10.10.20.30.0-0.3-0.30.3-0.40.3-0.4
Mean num. licks in bursts7.38.910.93.03.3-3.01.83.03.33.03.3
Std. dev. time between licks in bursts0.40.50.91.00.7-1.00.11.00.11.00.1
Water consumed over 24 hours1.11.32.4-1.1-1.11.1-1.5-1.1-0.9-1.1-0.9
Indifference point 0 sec0.30.51.50.40.6-0.61.20.40.70.70.9
Indifference point AUC0.50.61.20.40.8-0.51.10.41.00.51.1
Indifference point function ln k0.20.30.30.60.6-0.60.30.60.60.40.5
Indifference point function log k0.20.30.30.60.6-0.60.30.60.60.40.5
Delay discounting total patch changes 0 sec0.40.61.40.60.7-0.71.20.60.80.80.9
Delay discounting total patch changes 12 sec0.30.30.60.50.6-0.80.30.50.40.80.6
Delay discounting total patch changes 18 sec0.20.31.3-0.5-0.30.41.2-0.5-0.0-0.30.1
Delay discounting total patch changes 24 sec0.60.72.30.50.7-0.61.50.50.90.71.0
Delay discounting total patch changes 6 sec0.71.02.6-1.2-0.91.01.6-1.2-0.3-0.9-0.1
Delay discounting time to switch 0 sec1.72.56.6-0.9-1.40.9-2.6-0.9-2.0-0.9-2.0
Delay discounting water rate 0 sec0.30.51.10.70.7-0.61.00.70.60.60.6
Delay discounting water rate 12 sec1.21.85.80.91.2-0.82.40.91.50.81.5
Delay discounting water rate 18 sec0.30.40.60.60.6-0.50.80.60.60.50.5
Delay discounting water rate 24 sec0.30.51.10.40.6-0.21.00.41.00.21.0
Delay discounting water rate 6 sec0.30.42.2-0.4-0.20.51.5-0.40.3-0.60.3
Locomotor activity0.10.20.40.50.4-0.6-0.40.50.10.60.1
Locomotor testing distance0.30.60.80.80.8-0.90.60.80.60.90.7
Locomotor testing rearing0.10.20.40.50.4-0.6-0.20.5-0.10.6-0.0
Light reinforcement 10.00.10.3-0.1-0.20.1-0.4-0.1-0.50.1-0.4
Light reinforcement 20.00.10.20.30.2-0.20.20.30.00.40.1
Reaction time number correct0.50.71.6-0.6-0.90.70.3-0.6-1.3-0.6-1.2
Reaction time mean minus median0.20.21.30.10.2-0.11.10.10.40.10.4
Reaction time mean minus median AUC0.30.42.5-0.3-0.30.41.6-0.3-0.2-0.4-0.3
Reaction time num false alarms1.01.42.0-1.4-1.21.3-0.7-1.4-0.9-1.4-0.9
Reaction time num false alarms AUC0.60.81.0-1.0-0.90.8-0.9-1.0-0.8-1.0-0.8
Reaction time trials correct on left0.50.71.6-0.6-0.90.70.3-0.6-1.3-0.6-1.2
Reaction time trials on left0.50.71.6-0.6-0.90.60.3-0.6-1.3-0.6-1.2
Reaction time mean0.30.40.60.60.7-0.60.40.60.80.60.7
Reaction time mean AUC0.20.20.30.50.5-0.5-0.00.50.50.50.4
Median of all reaction times0.40.50.60.80.8-0.80.00.80.70.80.7
Reaction time omissions0.10.20.70.2-0.1-0.2-0.40.2-0.70.1-0.8
Reaction time false alarm rate0.20.30.8-0.6-0.40.5-0.9-0.6-0.1-0.6-0.1
Reaction time premature initiation rate1.11.42.21.01.3-1.2-0.81.01.51.11.5
Reaction time premature initiations0.30.40.60.50.7-0.7-0.80.50.60.60.6
Std. dev. reaction times0.20.30.90.40.5-0.40.90.40.70.40.6
Reaction time trials completed0.50.71.6-0.6-0.90.60.3-0.6-1.3-0.6-1.2
Reaction time trials AUC0.30.51.1-0.5-0.70.50.4-0.5-1.1-0.5-1.0
Social response proportion0.10.10.2-0.1-0.20.10.3-0.1-0.5-0.0-0.5
Social responses0.40.51.3-0.3-0.60.3-0.8-0.3-1.1-0.3-1.1
Social time1.41.82.0-1.3-1.41.2-1.4-1.3-1.4-1.3-1.4
Conditioned locomotion0.40.52.5-0.2-0.50.2-1.6-0.2-0.8-0.1-0.8
Cocaine response after cond. corrected0.30.30.4-0.6-0.60.60.0-0.6-0.5-0.7-0.5
Cocaine response after cond. not corrected0.00.00.10.20.2-0.20.20.20.30.10.2
Cocaine response before conditioning2.12.63.31.71.8-1.70.11.71.81.71.7
Saline control response0.00.00.1-0.1-0.20.10.2-0.1-0.3-0.2-0.3
Condit. Reinf. active minus inactive responses0.80.91.81.00.9-1.01.31.00.61.10.7
Condit. Reinf. active-inactive response ratio0.30.31.60.30.2-0.31.30.3-0.00.40.0
Condit. Reinf. active responses0.60.81.21.00.9-1.00.91.00.61.10.7
Condit. Reinf. inactive responses0.91.11.41.11.2-1.1-0.31.11.01.21.0
Condit. Reinf. lever presses1.62.33.11.61.6-1.61.01.61.21.71.3
Condit. Reinf. lever reinforcers received0.30.40.70.80.7-0.80.60.80.20.90.3
Pavlov. Cond. lever latency1.01.41.7-1.2-1.31.2-1.0-1.2-1.1-1.2-1.1
Pavlov. Cond. magazine entry latency1.01.22.3-0.7-1.00.7-1.5-0.7-1.4-0.8-1.5
Pavlov. Cond. change in total contacts0.10.10.8-0.2-0.20.20.9-0.2-0.1-0.2-0.2
Pavlov. Cond. index score0.00.00.10.1-0.0-0.1-0.10.1-0.30.1-0.4
Pavlov. Cond. latency score0.00.00.10.20.1-0.2-0.10.2-0.20.2-0.2
Pavlov. Cond. lever contacts1.31.82.31.51.5-1.50.81.51.11.51.1
Pavlov. Cond. magazine entry number1.82.23.41.31.6-1.31.21.31.81.41.8
Pavlov. Cond. intertrial magazine entries3.44.35.22.22.3-2.21.12.22.02.32.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.0-0.2-0.0-0.40.0-0.5-0.1-0.6
Pavlov. Cond. response bias0.20.20.40.60.5-0.60.30.60.10.50.1
Conditioned reinforcement - actives0.20.21.1-0.20.00.21.0-0.20.4-0.30.3
Conditioned reinforcement - inactives0.91.01.7-1.2-1.01.10.5-1.2-0.7-1.3-0.8
Conditioned locomotion0.20.20.3-0.4-0.60.6-0.5-0.4-0.2-0.5-0.3
Intermittent access intake day 1-15 change1.21.21.6-1.2-1.21.2-0.1-1.2-1.1-1.3-1.1
Intermittent access intake escalation1.01.01.3-1.1-1.01.10.2-1.1-0.9-1.2-0.9
Intermittent access intake escalation 21.11.11.4-1.2-1.11.1-0.2-1.2-1.0-1.1-1.0
Intermitt. access day 1 inactive lever presses0.20.20.3-0.5-0.40.50.2-0.5-0.2-0.5-0.2
Intermitt. access day 15 inactive lever presses0.30.30.50.60.6-0.50.40.60.70.50.6
Intermitt. access escalation Index1.00.91.40.90.9-0.91.20.90.81.00.9
Intermittent access day 1 total infusions1.11.31.81.11.1-1.11.31.11.11.11.1
Intermittent access day 15 total infusions0.20.21.9-0.00.00.01.4-0.00.1-0.10.1
Intermittent access terminal intake (last 3 days)0.20.21.50.00.1-0.01.20.00.2-0.00.1
Intermittent access total infusions0.70.82.50.70.8-0.71.60.70.80.60.8
Intermittent access day 1 locomotion1.21.33.21.01.0-1.01.81.01.00.91.0
Intermittent access day 15 total locomotion1.61.73.4-1.3-1.21.21.8-1.3-1.1-1.3-1.1
Intermittent access total locomotion0.91.06.50.50.6-0.62.50.50.50.50.4
Intermittent access standard deviation0.10.10.3-0.10.10.00.5-0.10.2-0.10.3
Cocaine induced anxiety0.20.21.0-0.1-0.20.11.0-0.1-0.4-0.1-0.4
Post-drug Anxiety0.40.51.0-0.7-0.60.71.0-0.7-0.4-0.7-0.4
Baseline Anxiety0.10.10.5-0.00.30.0-0.0-0.00.7-0.00.7
Lifetime Intake1.41.63.41.11.2-1.11.81.11.31.11.2
Incentive Sensitization - Responses0.10.10.40.20.1-0.2-0.60.2-0.10.1-0.1
Incentive Sensitization - Breakpoint0.00.00.20.20.1-0.2-0.50.2-0.00.2-0.0
Progressive ratio test 1 active lever presses0.50.51.50.60.6-0.61.20.60.50.50.5
Progressive ratio test 1 breakpoint0.40.41.30.60.6-0.61.10.60.50.50.4
Progressive ratio test 1 inactive lever presses0.50.51.50.70.7-0.71.20.70.70.50.5
Progressive ratio test 2 active lever presses0.10.10.30.40.4-0.30.60.40.40.30.3
Progressive ratio test 2 breakpoint0.10.10.30.40.4-0.30.60.40.30.30.2
Progressive ratio test 2 inactive lever presses0.10.10.60.20.1-0.10.80.20.10.00.0
Total sessions with >9 infusions3.94.35.82.02.2-1.91.72.02.41.92.3
Short access day 1 total inactive lever presses0.00.00.2-0.1-0.00.00.5-0.10.1-0.3-0.0
Short access day 10 total inactive lever presses1.11.21.6-1.3-1.21.2-0.2-1.3-0.9-1.2-0.9
Short access day 1 total infusions0.91.01.50.91.1-0.91.00.91.20.71.0
Short access day 10 total infusions1.41.51.81.21.3-1.21.21.21.31.11.2
Short access total infusions2.42.73.81.51.7-1.52.01.51.81.51.7
Short access day 1 locomotion0.10.10.40.10.2-0.10.60.10.4-0.10.3
Short access day 10 total locomotion2.72.94.41.71.8-1.82.11.71.51.61.5
Short access total locomotion2.32.46.41.31.4-1.32.51.31.51.21.4
Compulsive drug intake0.60.61.00.90.8-0.90.00.90.51.00.6
One hour access (0.3 mA shock)2.73.16.31.71.7-1.72.51.71.51.71.5
One hour access (shock baseline)0.30.41.6-0.5-0.50.51.3-0.5-0.3-0.6-0.3
Number of responses in last shaping day0.50.50.70.80.8-0.8-0.00.80.80.70.7
Context. condit. distance diff. score0.20.30.8-0.3-0.40.2-0.4-0.3-0.8-0.3-0.9
Locomotion velocity, session 10.10.10.1-0.4-0.10.20.1-0.40.1-0.40.0
Locomotion distance, session 10.91.21.51.11.2-1.20.71.11.21.11.1
Locomotion velocity, session 20.40.40.8-0.8-0.70.9-0.3-0.8-0.2-0.8-0.2
Locomotion distance, session 21.62.23.31.41.6-1.41.11.41.81.41.8
Locomotion velocity, session 30.30.30.40.60.6-0.50.10.60.70.60.7
Locomotion distance, session 30.30.30.50.60.5-0.6-0.70.60.40.60.4
Stereotopy head waving bouts, day 30.40.50.7-0.8-0.80.8-0.3-0.8-0.8-0.8-0.8
Stereotopy head waving duration, day 30.20.30.4-0.5-0.60.6-0.1-0.5-0.5-0.5-0.5
Locomotion velocity, session 71.31.52.01.41.3-1.3-0.11.41.11.41.0
Locomotion distance, session 70.10.10.40.20.2-0.2-0.60.20.10.2-0.0
Stereotopy head waving bouts, day 70.20.20.50.40.4-0.30.70.40.50.40.6
Stereotopy head waving duration, day 71.72.12.51.61.5-1.51.01.61.41.61.5
Locomotion velocity, session 80.00.00.0-0.10.00.10.2-0.10.1-0.10.2
Locomotion distance, session 80.20.30.50.60.6-0.70.40.60.50.60.3
Degree of sensitization distance0.30.30.7-0.6-0.50.50.8-0.6-0.2-0.6-0.2
Degree of sensitization stereotypy1.31.41.71.21.3-1.10.81.21.31.21.3
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.1-0.0-0.2-0.1-0.4-0.1-0.4
Condit. Reinf. active-inactive response ratio0.10.10.30.40.2-0.5-0.50.4-0.20.4-0.2
Condit. Reinf. active responses0.10.10.1-0.2-0.20.10.3-0.2-0.3-0.2-0.3
Condit. Reinf. inactive responses0.10.10.9-0.2-0.10.21.0-0.2-0.0-0.10.1
Incentive salience index mean0.10.20.30.50.4-0.6-0.30.50.10.50.0
Condit. Reinf. lever presses0.20.20.60.50.2-0.4-0.80.5-0.30.5-0.3
Time in familiar zone, hab. session 11.21.21.6-1.3-1.01.21.2-1.3-0.5-1.3-0.5
Time in novel zone, hab. session 11.41.32.01.31.0-1.2-1.41.30.51.30.6
Total zone transitions, hab. session 12.23.05.01.31.8-1.42.01.32.21.32.2
Total locomotion distance, hab. session 15.37.511.32.32.9-2.42.82.33.32.33.4
Locomotion velocity, hab. session 14.66.69.02.32.7-2.32.72.33.02.33.0
Time in familiar zone, hab. session 20.30.40.80.30.6-0.40.90.30.70.30.8
Time in novel zone, hab. session 20.00.00.20.1-0.1-0.0-0.40.1-0.30.1-0.3
Total zone transitions, hab. session 22.02.63.61.41.8-1.51.51.41.91.41.9
Total locomotion distance, hab. session 22.73.66.01.52.0-1.62.01.52.41.52.4
Locomotion velocity, hab. session 23.44.66.91.82.3-1.92.11.82.61.82.6
Novel to familiar place preference ratio0.90.91.3-1.1-1.01.10.2-1.1-0.8-1.1-0.8
Novelty place preference1.21.21.8-1.3-1.21.30.2-1.3-0.8-1.3-0.8
Time in novel zone, NPP test1.01.01.4-1.2-1.11.10.4-1.2-0.8-1.2-0.8
Total zone transitions, NPP test1.42.13.11.31.5-1.31.31.31.81.31.8
Total locomotion distance, NPP test1.52.13.81.11.4-1.01.71.11.91.12.0
Locomotion velocity, NPP test1.11.63.20.91.2-0.81.40.91.80.91.8
Pavlov. Cond. lever latency2.32.94.7-2.2-1.72.21.2-2.2-0.6-2.2-0.6
Pavlov. Cond. magazine entry latency4.86.39.63.12.6-3.1-0.33.11.63.11.5
Pavlov. Cond. change in total contacts2.72.94.42.11.6-2.0-1.72.10.62.10.6
Pavlov. Cond. index score3.54.47.22.72.1-2.6-1.22.70.92.70.8
Pavlov. Cond. latency score3.14.06.52.52.0-2.5-0.92.50.92.50.8
Pavlov. Cond. lever contacts3.54.26.72.62.0-2.6-1.12.60.92.60.8
Pavlov. Cond. magazine entry number3.24.06.3-2.5-1.92.41.5-2.5-0.9-2.5-0.8
Pavlov. Cond. intertrial magazine entries1.72.03.1-1.7-1.51.70.6-1.7-1.0-1.7-0.9
Pavlov. Cond. lever-magazine prob. diff.4.35.48.72.92.3-2.9-1.02.91.12.91.0
Pavlov. Cond. response bias3.54.36.62.62.0-2.6-1.62.60.82.60.8
Bone: apparent density0.81.42.01.01.3-1.21.01.01.41.01.4
Bone surface1.01.72.31.31.5-1.40.11.31.41.31.5
Bone volume1.62.63.81.51.8-1.60.91.51.91.51.9
Bone: connectivity density0.61.01.51.01.2-1.20.41.00.91.00.9
Bone: cortical apparent density0.81.11.3-1.1-1.11.2-0.6-1.1-0.9-1.1-1.0
Bone: cortical area3.04.67.02.02.3-2.01.22.02.62.12.6
Bone: cortical porosity1.21.21.71.31.2-1.20.51.30.91.30.9
Bone: cortical porosity0.50.50.90.90.7-0.90.10.90.41.00.4
Bone: cortical thickness1.01.63.70.81.2-0.71.40.81.90.81.9
Bone: cortical thickness0.40.51.1-0.7-0.20.71.1-0.70.8-0.70.8
Bone: cortical tissue density0.81.11.3-1.1-1.21.2-0.6-1.1-0.9-1.1-1.0
Bone: elastic displacement0.91.01.5-1.2-1.01.20.3-1.2-0.7-1.2-0.5
Bone: elastic work0.10.20.60.10.4-0.10.40.10.70.20.8
Bone: endosteal estimation2.04.46.12.32.4-2.50.12.31.92.31.9
Bone: endosteal perimeter1.12.33.11.81.7-1.7-0.31.81.41.71.3
Bone: final force5.48.912.12.93.3-2.91.72.93.52.93.5
Bone: final moment4.67.510.22.63.0-2.71.72.63.22.73.2
Bone: marrow area1.83.95.42.22.3-2.30.02.21.82.21.8
Bone: maximum diameter2.34.25.02.22.2-2.00.52.22.22.12.2
Bone: maximum force4.17.110.32.52.9-2.51.32.53.22.63.2
Bone: maximum moment3.35.88.42.32.6-2.31.32.32.92.32.9
Bone: minimum diameter2.13.94.72.12.2-2.00.42.12.02.22.1
Bone: periosteal estimation3.46.98.62.72.9-2.70.82.72.82.72.8
Bone: periosteal perimeter2.03.34.42.02.0-1.90.42.01.72.11.7
Bone: post-yield work3.14.25.62.32.3-2.40.92.31.82.21.8
Bone: stiffness2.84.57.61.92.3-1.91.21.92.81.92.7
Bone: tissue strength0.00.00.1-0.1-0.00.1-0.2-0.10.1-0.10.1
Bone: trabecular number0.50.81.20.60.9-0.71.10.61.10.61.1
Bone: trabecular spacing0.40.61.60.2-0.50.0-1.30.2-1.10.2-1.2
Bone: trabecular thickness1.72.16.20.71.2-0.72.50.71.90.72.0
Bone: trabecular tissue density0.00.00.1-0.2-0.10.30.1-0.20.2-0.20.1
Breakpoint value in progressive ratio session1.31.42.1-1.1-1.41.2-0.8-1.1-1.4-1.1-1.3
Distance traveled before self-admin0.30.31.1-0.6-0.30.61.0-0.60.1-0.60.1
Distance traveled after self-admin1.21.32.50.91.2-0.90.90.91.50.91.6
Delta time in closed arm before/after self-admin0.50.53.60.3-0.1-0.1-1.90.3-0.40.3-0.4
Delta time in open arm before/after self-admin2.92.85.81.31.6-1.42.41.31.81.31.8
Diff in mean of infusions in LGA sessions0.70.82.2-0.8-0.80.81.5-0.8-0.8-0.8-0.7
Extinction: sum of active levers before priming0.20.20.4-0.5-0.60.5-0.0-0.5-0.6-0.5-0.5
Active lever presses in extinction session 60.10.10.5-0.1-0.30.30.7-0.1-0.4-0.1-0.1
Delta distance traveled before/after self-admin1.61.72.21.51.5-1.40.11.51.21.51.3
Delta ambulatory time before/after self-admin1.21.31.61.21.3-1.2-0.01.21.21.21.2
Time in closed arm before self-admin0.70.83.00.50.8-0.51.70.51.00.51.0
Time in closed arm after self-admin0.90.91.5-1.1-1.11.2-0.1-1.1-0.8-1.1-0.7
Time in open arm before self-admin2.02.13.3-1.2-1.41.1-1.8-1.2-1.7-1.2-1.8
Time in open arm after self-admin1.51.62.01.21.4-1.40.91.21.41.21.3
Sum of active levers in priming session hrs 5-60.10.10.20.50.1-0.40.00.5-0.20.5-0.2
Time to tail flick, vehicle, before self-admin0.30.30.40.60.6-0.6-0.00.60.60.60.5
Time to tail flick, vehicle, after self-admin1.31.32.7-0.7-1.10.8-1.5-0.7-1.5-0.7-1.6
Time to tail flick, test, before self-admin0.00.00.10.00.1-0.1-0.30.00.30.00.0
Time to tail flick, test, after self-admin0.70.71.5-0.5-0.80.5-1.1-0.5-1.2-0.5-1.2
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.1-0.30.1-0.4-0.1-0.7-0.1-0.6
Delta time to tail flick, test, before/after SA0.10.10.20.2-0.1-0.0-0.10.2-0.50.2-0.4
Ambulatory time before self-admin0.60.60.9-0.9-0.61.00.9-0.9-0.1-1.0-0.1
Ambulatory time after self-admin1.01.12.40.81.2-0.80.70.81.50.81.5
Total heroin consumption0.30.40.9-0.4-0.60.4-0.5-0.4-1.0-0.4-1.0
Area under the delay curve0.50.60.9-0.8-0.81.0-0.3-0.8-0.5-1.0-0.5
Delay disc. indifference point, 0s delay0.20.20.70.30.4-0.10.50.30.9-0.20.6
Delay disc. indifference point, 16s delay5.85.97.0-2.6-2.72.6-1.2-2.6-2.4-2.6-2.4
Delay disc. indifference point, 2s delay3.53.95.62.02.1-1.81.62.02.41.72.3
Delay disc. indifference point, 24s delay4.84.65.3-2.2-2.32.2-1.5-2.2-2.3-2.1-2.2
Delay disc. indifference point, 4s delay0.40.40.7-0.6-0.50.90.7-0.60.2-0.80.2
Delay disc. indifference point, 8s delay0.20.20.4-0.5-0.40.6-0.3-0.5-0.1-0.50.0
Delay discount exponential model param0.50.50.80.80.8-0.90.40.80.50.90.5
Delay discount hyperbolic model param0.20.20.50.60.5-0.70.10.60.20.70.2
Fecal boli incidents, locomotor time 10.40.41.20.0-0.2-0.1-1.00.0-1.10.0-1.1
Change in fecal boli incidents, locomotor task0.50.51.4-0.3-0.20.81.2-0.30.7-0.11.0
Time >=10cm from walls, locomotor time 10.40.41.40.40.7-0.51.20.40.80.30.6
Bouts of movement, locomotor time 12.32.64.3-1.5-1.81.4-0.6-1.5-2.1-1.4-2.1
Total resting periods, locomotor time 12.93.25.2-1.6-2.01.7-1.2-1.6-2.3-1.6-2.3
Rest time, locomotor task time 11.71.93.6-1.2-1.31.3-1.9-1.2-1.2-1.3-1.3
Distance moved, locomotor task time 12.42.64.01.41.6-1.42.01.41.71.51.7
Vertical activity count, locomotor time 13.23.37.71.21.7-1.32.81.22.31.32.2
Time >=10cm from walls, locomotor time 21.51.62.81.11.5-1.30.71.11.70.91.5
Bouts of movement, locomotor time 21.21.32.51.61.0-1.5-0.71.60.11.3-0.1
Total resting periods, locomotor time 21.51.63.01.71.2-1.7-0.51.70.41.40.2
Rest time, locomotor task time 20.00.00.1-0.3-0.20.20.1-0.3-0.1-0.20.1
Distance moved, locomotor task time 20.30.41.10.40.7-0.40.40.41.00.40.9
Vertical activity count, locomotor time 20.50.51.4-0.10.50.01.2-0.11.20.01.1
Weight adjusted by age0.80.91.71.21.0-1.30.21.20.31.30.3
Seeking ratio, delayed vs. immediate footshock0.00.00.3-0.10.00.10.6-0.10.0-0.00.1
Locomotion in novel chamber1.21.53.51.21.1-1.21.91.20.91.10.8
Locomotion in novel chamber post-restriction0.30.42.7-0.3-0.40.31.6-0.3-0.4-0.1-0.2
Progressive ratio0.20.21.0-0.2-0.30.51.0-0.20.1-0.20.1
Food seeking constrained by brief footshock1.82.23.4-1.5-1.61.6-1.0-1.5-1.2-1.8-1.4
Seeking ratio, punishment vs. effort0.20.21.20.20.3-0.4-1.10.2-0.10.1-0.2
Run reversals in cocaine runway, females4.84.77.82.12.3-2.00.92.12.82.02.7
Run reversals in cocaine runway, males0.70.61.2-0.8-0.80.9-0.1-0.8-0.6-1.1-0.8
Latency to leave start box in cocaine runway0.20.30.3-0.6-0.50.50.5-0.6-0.4-0.6-0.4
Latency to leave start box in cocaine runway, F0.20.20.5-0.2-0.30.1-0.6-0.2-0.7-0.2-0.7
Latency to leave start box in cocaine runway, M0.80.71.3-1.0-0.71.01.2-1.0-0.1-1.0-0.1
Cd content in liver4.65.16.3-2.3-2.52.3-1.0-2.3-2.5-2.3-2.5
Co content in liver1.11.31.9-1.4-1.21.40.7-1.4-0.6-1.4-0.6
Cu content in liver0.50.63.40.10.3-0.11.80.10.70.10.7
Fe content in liver1.51.82.6-1.6-1.41.60.5-1.6-0.9-1.6-0.9
K content in liver0.20.20.50.40.4-0.40.70.40.20.40.2
Mg content in liver0.30.30.40.60.3-0.6-0.30.6-0.40.6-0.4
Mn content in liver0.30.40.50.70.6-0.7-0.50.70.40.70.4
Na content in liver5.55.97.32.72.7-2.70.52.72.32.72.3
Rb content in liver0.81.11.4-1.1-1.11.11.2-1.1-0.8-1.1-0.8
Se content in liver0.10.10.10.20.3-0.20.30.20.30.20.3
Sr content in liver0.70.70.80.90.9-0.90.10.90.80.90.8
Zn content in liver4.04.45.32.32.3-2.31.12.31.92.31.9