Hub : Genes

Pex6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016655 0.34 0.11 0.0e+00 0.36 0.36 0.36 0.36 7.7e-42 1.0e-41 1.9e-41 7.0e-42
2 Adipose mRNA stability ENSRNOG00000016655 0.07 0.04 6.6e-08 0.06 0.06 0.06 0.06 2.0e-07 1.1e-07 3.6e-07 2.5e-07
3 BLA gene expression ENSRNOG00000016655 0.53 0.15 0.0e+00 0.54 0.57 0.57 0.57 3.6e-34 3.0e-36 4.3e-36 3.3e-36
4 Brain gene expression ENSRNOG00000016655 0.36 0.13 0.0e+00 0.44 0.42 0.43 0.44 3.2e-44 4.6e-42 9.3e-44 6.5e-44
5 Eye gene expression ENSRNOG00000016655 0.34 0.16 8.4e-04 0.23 0.12 0.06 0.09 2.2e-04 7.0e-03 4.0e-02 1.8e-02
6 IL gene expression ENSRNOG00000016655 0.54 0.16 3.3e-11 0.4 0.36 0.36 0.39 9.4e-11 1.5e-09 1.5e-09 2.0e-10
7 LHb gene expression ENSRNOG00000016655 0.26 0.14 3.6e-05 0.21 0.19 0.17 0.21 1.0e-05 2.4e-05 8.6e-05 1.2e-05
8 Liver gene expression ENSRNOG00000016655 0.47 0.11 0.0e+00 0.44 0.44 0.45 0.44 1.6e-53 3.0e-54 1.0e-54 5.9e-54
9 Liver intron excision ratio chr9:14266842:14267513 0.06 0.03 4.3e-07 0.04 0.05 0.05 0.05 7.9e-05 1.3e-06 2.9e-06 1.7e-06
10 Liver intron excision ratio chr9:14267676:14269402 0.05 0.03 1.7e-06 0.03 0.05 0.04 0.04 2.8e-04 5.6e-06 1.2e-05 1.0e-05
11 Liver mRNA stability ENSRNOG00000016655 0.13 0.07 2.8e-16 0.14 0.13 0.13 0.13 4.6e-15 2.8e-14 4.9e-14 1.2e-14
12 NAcc gene expression ENSRNOG00000016655 0.31 0.12 0.0e+00 0.32 0.35 0.34 0.34 2.1e-24 8.6e-27 9.0e-26 2.1e-26
13 OFC gene expression ENSRNOG00000016655 0.57 0.14 4.6e-13 0.35 0.33 0.32 0.35 4.1e-09 9.6e-09 2.7e-08 3.9e-09
14 PL gene expression ENSRNOG00000016655 0.64 0.15 0.0e+00 0.63 0.63 0.62 0.63 2.1e-60 9.4e-61 5.4e-60 1.1e-61

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail3.812.314.5-3.7-3.8-3.5-3.7-3.6-3.6-3.8-3.6-2.62.6-3.6-3.5-3.7-3.7
BMI without tail11.824.828.2-5.1-5.3-5.0-5.3-5.0-5.1-5.3-5.1-4.03.9-5.0-5.0-5.2-5.0
Body weight3.012.513.9-3.6-3.7-3.5-3.6-3.5-3.6-3.7-3.6-3.23.1-3.5-3.7-3.6-3.5
Epididymis fat weight2.45.67.0-2.3-2.2-2.4-2.3-2.3-2.2-2.3-2.4-2.62.6-2.3-2.5-2.3-2.3
Glucose5.48.39.2-2.8-2.9-2.9-2.8-3.0-3.0-2.8-3.0-2.72.7-2.9-2.9-2.8-2.9
Heart weight1.52.22.51.51.41.51.41.41.41.51.41.6-1.61.41.51.51.5
Left kidney weight0.10.20.5-0.5-0.7-0.2-0.5-0.5-0.5-0.5-0.40.4-0.4-0.5-0.4-0.5-0.5
Right kidney weight0.10.21.10.1-0.20.3-0.00.0-0.0-0.00.21.0-1.10.00.2-0.00.1
Tail length2.05.97.1-2.4-2.5-2.4-2.6-2.3-2.4-2.5-2.5-2.42.3-2.4-2.7-2.5-2.3
Length with tail0.10.30.7-0.4-0.6-0.4-0.5-0.5-0.5-0.4-0.6-0.80.7-0.4-0.8-0.5-0.4
Length without tail2.65.77.12.42.52.52.72.52.42.62.51.8-1.82.42.32.62.4
Liver weight, left0.30.41.0-0.7-0.8-0.5-0.7-0.9-1.0-0.6-0.5-0.10.0-0.8-0.6-0.7-0.7
Liver weight, right0.61.01.3-1.0-1.0-0.9-0.9-1.0-1.0-0.9-0.9-1.01.0-1.0-1.1-1.0-1.0
Parametrial fat weight6.612.913.8-3.6-3.6-3.5-3.7-3.6-3.6-3.6-3.7-3.43.3-3.7-3.7-3.6-3.6
Retroperitoneal fat weight1.44.66.1-2.3-2.5-2.0-2.3-2.3-2.2-2.3-2.1-1.21.2-2.3-2.1-2.2-2.3
Intraocular pressure0.91.31.91.11.21.01.11.11.21.21.11.3-1.21.11.41.11.1
Extensor digitorum longus weight0.10.30.4-0.6-0.6-0.4-0.5-0.5-0.6-0.6-0.6-0.30.3-0.5-0.5-0.6-0.5
Soleus weight0.41.11.4-1.1-1.1-1.0-1.0-1.0-1.1-1.0-1.1-1.00.9-1.1-1.2-1.1-1.0
Tibialis anterior weight0.20.70.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.80.8-0.7-0.8-0.8-0.7
Tibia length2.15.97.3-2.5-2.7-2.4-2.6-2.6-2.7-2.6-2.3-1.51.5-2.6-2.4-2.6-2.6
Number of licking bursts4.45.27.3-2.2-2.1-2.4-2.1-2.2-2.1-2.1-2.4-2.72.7-2.2-2.4-2.2-2.2
Food consumed during 24 hour testing period0.40.50.8-0.7-0.8-0.6-0.7-0.9-0.8-0.8-0.6-0.10.1-0.9-0.6-0.7-0.9
Times rat made contact with spout5.76.67.1-2.5-2.5-2.7-2.5-2.6-2.6-2.5-2.6-2.62.6-2.6-2.6-2.5-2.6
Mean time between licks in bursts1.21.72.41.41.51.11.31.51.41.31.20.6-0.51.61.31.31.6
Mean num. licks in bursts0.60.81.50.80.70.90.70.80.70.80.91.2-1.20.81.00.70.8
Std. dev. time between licks in bursts2.02.43.01.71.61.51.41.71.71.41.41.4-1.41.71.61.41.7
Water consumed over 24 hours1.92.33.0-1.6-1.7-1.4-1.6-1.7-1.6-1.6-1.4-0.90.8-1.6-1.5-1.6-1.6
Indifference point 0 sec0.81.31.6-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.1-1.01.0-1.1-1.1-1.2-1.1
Indifference point AUC0.50.61.1-0.8-1.1-0.6-0.9-0.9-0.9-0.9-0.50.3-0.3-0.9-0.6-0.8-0.9
Indifference point function ln k0.40.60.80.80.80.70.90.80.80.70.80.8-0.70.80.90.80.8
Indifference point function log k0.40.60.80.80.80.70.90.80.80.70.80.8-0.70.80.90.80.8
Delay discounting total patch changes 0 sec1.01.72.1-1.2-1.3-1.4-1.4-1.3-1.3-1.4-1.3-1.11.1-1.2-1.3-1.4-1.3
Delay discounting total patch changes 12 sec0.70.91.6-1.0-1.3-0.8-1.2-1.1-1.0-1.1-0.8-0.30.2-1.0-1.0-1.1-1.0
Delay discounting total patch changes 18 sec1.11.52.3-1.2-1.5-1.1-1.4-1.3-1.3-1.5-1.0-0.50.5-1.2-1.2-1.3-1.3
Delay discounting total patch changes 24 sec0.70.91.5-0.9-1.1-0.9-1.2-0.9-0.9-1.2-0.9-0.50.4-0.9-0.9-1.1-0.9
Delay discounting total patch changes 6 sec2.03.14.0-1.8-1.9-1.7-1.8-1.8-1.8-2.0-1.7-1.41.3-1.8-1.8-1.8-1.8
Delay discounting time to switch 0 sec3.95.97.92.62.82.42.62.72.72.72.21.2-1.22.72.32.62.7
Delay discounting water rate 0 sec1.72.74.7-1.7-2.2-1.5-1.9-1.8-1.8-1.9-1.4-0.0-0.0-1.8-1.4-2.0-1.8
Delay discounting water rate 12 sec4.77.19.1-2.8-3.0-2.6-2.8-2.7-2.8-2.9-2.6-1.81.8-2.7-2.7-3.0-2.7
Delay discounting water rate 18 sec1.01.41.9-1.2-1.3-1.1-1.3-1.1-1.2-1.3-1.1-0.60.6-1.2-1.1-1.4-1.2
Delay discounting water rate 24 sec1.62.22.9-1.6-1.7-1.5-1.6-1.6-1.6-1.6-1.4-0.80.8-1.6-1.4-1.7-1.6
Delay discounting water rate 6 sec0.10.20.4-0.4-0.6-0.2-0.4-0.4-0.4-0.5-0.10.5-0.5-0.4-0.2-0.5-0.4
Locomotor activity2.74.24.7-2.0-2.0-2.0-1.9-2.2-2.1-1.9-2.0-2.22.1-2.2-2.2-1.9-2.2
Locomotor testing distance2.33.84.5-1.9-1.8-1.9-1.8-2.0-1.9-1.9-2.0-2.12.1-2.0-2.1-1.8-2.0
Locomotor testing rearing3.14.96.1-2.3-2.4-2.1-2.2-2.5-2.3-2.3-2.2-1.61.5-2.4-2.2-2.3-2.5
Light reinforcement 11.93.44.1-1.9-2.0-1.8-2.0-2.0-2.0-1.9-1.8-1.31.3-1.9-1.9-1.9-2.0
Light reinforcement 23.03.95.1-2.0-1.9-2.0-2.0-1.8-2.0-1.9-2.1-2.32.2-1.8-2.1-1.9-1.8
Reaction time number correct0.30.41.40.40.20.50.30.50.40.30.71.2-1.20.40.60.40.5
Reaction time mean minus median0.10.10.20.30.30.40.40.20.20.40.30.1-0.20.20.20.50.2
Reaction time mean minus median AUC0.20.30.50.60.70.50.70.50.50.70.60.2-0.20.50.50.70.5
Reaction time num false alarms0.71.01.21.01.01.01.01.01.11.11.00.8-0.81.01.01.01.0
Reaction time num false alarms AUC0.50.70.90.80.80.90.90.80.90.90.90.8-0.80.80.80.90.8
Reaction time trials correct on left0.30.41.40.40.20.50.30.50.40.30.71.2-1.20.40.60.40.5
Reaction time trials on left0.20.31.20.40.20.50.30.40.40.20.61.1-1.10.40.50.30.4
Reaction time mean0.10.20.80.20.40.00.30.20.20.4-0.1-0.90.90.2-0.10.30.2
Reaction time mean AUC0.20.21.20.10.4-0.10.30.10.10.3-0.2-1.11.10.2-0.20.30.2
Median of all reaction times0.20.21.20.00.3-0.20.20.10.00.2-0.3-1.11.10.1-0.30.10.1
Reaction time omissions0.60.81.0-0.9-0.8-0.9-0.8-0.9-0.9-0.8-0.9-1.01.0-0.9-0.9-0.7-0.9
Reaction time false alarm rate0.50.71.00.81.00.81.00.80.91.00.80.3-0.30.80.70.90.8
Reaction time premature initiation rate1.01.31.5-1.1-1.2-1.2-1.2-1.2-1.1-1.1-1.2-1.01.0-1.2-1.2-1.2-1.2
Reaction time premature initiations0.60.91.4-1.0-1.2-0.9-1.1-1.0-0.9-1.0-0.9-0.40.4-1.0-0.9-1.1-1.0
Std. dev. reaction times0.10.10.30.30.40.20.40.20.30.50.1-0.60.50.3-0.00.40.3
Reaction time trials completed0.20.31.20.40.20.50.30.40.40.20.61.1-1.10.40.50.30.4
Reaction time trials AUC0.10.21.00.20.00.40.10.30.20.10.51.0-1.00.30.40.20.3
Social response proportion1.01.01.51.11.11.01.11.21.11.00.90.6-0.61.20.81.11.2
Social responses2.22.93.51.81.71.81.81.81.91.81.61.2-1.31.81.51.71.8
Social time2.12.75.51.51.21.81.51.51.41.61.72.3-2.41.51.61.41.5
Conditioned locomotion2.32.74.41.61.41.71.41.51.51.51.62.1-2.11.61.71.41.6
Cocaine response after cond. corrected0.20.30.30.50.60.50.60.50.50.50.50.4-0.40.50.60.50.5
Cocaine response after cond. not corrected0.40.50.60.60.70.70.70.60.60.70.70.7-0.70.60.80.80.6
Cocaine response before conditioning0.00.00.1-0.2-0.2-0.0-0.1-0.2-0.1-0.1-0.00.3-0.3-0.2-0.0-0.0-0.2
Saline control response0.00.00.10.0-0.00.10.10.0-0.10.10.10.2-0.20.10.00.10.1
Condit. Reinf. active minus inactive responses0.10.10.4-0.2-0.1-0.3-0.1-0.3-0.2-0.1-0.2-0.60.6-0.3-0.2-0.1-0.3
Condit. Reinf. active-inactive response ratio1.21.32.3-1.1-0.9-1.2-0.9-1.1-1.1-0.9-1.1-1.51.5-1.1-1.1-0.9-1.1
Condit. Reinf. active responses0.00.00.0-0.00.0-0.1-0.0-0.10.0-0.0-0.0-0.20.2-0.1-0.00.0-0.1
Condit. Reinf. inactive responses0.10.10.30.30.20.30.10.30.40.10.30.5-0.60.30.30.10.3
Condit. Reinf. lever presses0.60.81.4-0.9-0.8-1.0-0.9-0.8-0.8-0.9-1.0-1.21.2-0.8-1.0-0.8-0.8
Condit. Reinf. lever reinforcers received0.00.00.00.00.1-0.00.0-0.10.10.0-0.0-0.20.2-0.1-0.00.1-0.1
Pavlov. Cond. lever latency2.73.74.91.81.82.01.91.71.81.92.12.2-2.21.72.11.81.7
Pavlov. Cond. magazine entry latency1.82.12.8-1.4-1.5-1.4-1.5-1.3-1.4-1.5-1.5-1.71.6-1.3-1.7-1.4-1.3
Pavlov. Cond. change in total contacts2.73.85.1-1.8-1.8-1.9-1.9-1.8-1.8-1.9-2.0-2.32.2-1.9-2.1-1.8-1.9
Pavlov. Cond. index score4.66.17.4-2.4-2.5-2.5-2.5-2.2-2.4-2.5-2.6-2.72.6-2.3-2.7-2.4-2.3
Pavlov. Cond. latency score5.16.47.7-2.5-2.5-2.5-2.5-2.3-2.4-2.5-2.7-2.72.7-2.3-2.8-2.5-2.3
Pavlov. Cond. lever contacts2.94.15.4-1.9-2.0-2.0-2.0-1.8-1.8-2.0-2.2-2.32.3-1.8-2.3-1.9-1.8
Pavlov. Cond. magazine entry number0.81.01.60.91.00.91.00.80.81.01.11.3-1.20.81.20.90.8
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.00.0-0.00.1-0.1-0.10.00.00.3-0.2-0.10.2-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.4.66.07.4-2.4-2.4-2.5-2.5-2.2-2.3-2.5-2.6-2.72.6-2.2-2.7-2.4-2.2
Pavlov. Cond. response bias1.01.42.6-1.1-1.1-1.1-1.2-0.9-1.0-1.2-1.3-1.61.6-0.9-1.4-1.1-0.9
Conditioned reinforcement - actives1.31.22.21.00.81.11.01.11.11.01.21.5-1.51.01.11.01.0
Conditioned reinforcement - inactives0.50.51.0-0.8-1.0-0.7-0.7-0.6-0.7-0.8-0.7-0.20.2-0.7-0.7-1.0-0.8
Conditioned locomotion0.00.00.0-0.0-0.1-0.00.10.10.10.1-0.00.0-0.00.0-0.0-0.20.0
Intermittent access intake day 1-15 change0.00.00.1-0.1-0.2-0.0-0.1-0.1-0.1-0.1-0.00.3-0.3-0.1-0.1-0.1-0.1
Intermittent access intake escalation0.00.00.00.00.00.10.10.10.10.00.10.2-0.20.1-0.00.10.1
Intermittent access intake escalation 20.00.00.1-0.2-0.3-0.0-0.1-0.1-0.1-0.2-0.10.2-0.3-0.1-0.2-0.2-0.2
Intermitt. access day 1 inactive lever presses1.31.41.8-1.3-1.3-1.2-1.2-1.1-1.1-1.3-1.3-1.01.0-1.2-1.2-1.3-1.3
Intermitt. access day 15 inactive lever presses1.61.82.2-1.5-1.5-1.4-1.3-1.3-1.3-1.4-1.5-1.11.1-1.3-1.4-1.4-1.4
Intermitt. access escalation Index0.00.00.00.10.10.00.1-0.10.00.10.00.00.0-0.10.10.10.1
Intermittent access day 1 total infusions0.70.81.3-0.9-0.8-1.0-0.8-0.8-0.8-0.8-1.0-1.11.2-0.8-0.9-0.9-0.8
Intermittent access day 15 total infusions0.30.40.6-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.7-0.70.7-0.5-0.7-0.6-0.5
Intermittent access terminal intake (last 3 days)0.20.20.5-0.5-0.4-0.5-0.3-0.3-0.3-0.3-0.6-0.70.7-0.3-0.5-0.4-0.3
Intermittent access total infusions0.20.20.5-0.4-0.3-0.5-0.3-0.2-0.2-0.2-0.5-0.70.7-0.3-0.4-0.4-0.3
Intermittent access day 1 locomotion0.40.41.0-0.5-0.5-0.7-0.5-0.5-0.5-0.5-0.7-1.01.0-0.5-0.6-0.6-0.5
Intermittent access day 15 total locomotion0.30.30.4-0.5-0.6-0.6-0.5-0.5-0.5-0.5-0.6-0.60.5-0.6-0.6-0.6-0.5
Intermittent access total locomotion0.10.10.6-0.2-0.1-0.3-0.1-0.1-0.1-0.1-0.4-0.80.8-0.2-0.3-0.3-0.1
Intermittent access standard deviation2.83.03.81.81.91.71.91.91.91.91.61.0-1.01.91.61.91.9
Cocaine induced anxiety0.10.20.3-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.60.6-0.4-0.4-0.3-0.4
Post-drug Anxiety0.00.10.3-0.10.1-0.1-0.1-0.1-0.1-0.1-0.2-0.50.5-0.1-0.20.1-0.1
Baseline Anxiety0.20.20.30.50.50.50.50.50.50.50.50.3-0.40.50.40.60.5
Lifetime Intake0.00.00.10.20.20.10.30.30.30.30.1-0.10.10.30.10.20.3
Incentive Sensitization - Responses0.90.91.5-1.0-1.2-1.0-1.0-1.0-0.9-1.0-1.0-0.60.6-1.0-1.0-1.2-0.9
Incentive Sensitization - Breakpoint1.01.01.5-1.1-1.2-1.0-1.0-1.0-1.0-1.0-1.0-0.60.6-1.1-1.0-1.2-1.0
Progressive ratio test 1 active lever presses1.41.42.3-1.2-1.0-1.3-1.1-1.0-1.0-1.1-1.3-1.51.5-1.1-1.2-1.2-1.1
Progressive ratio test 1 breakpoint1.11.11.6-1.1-1.0-1.1-1.0-0.9-0.9-1.0-1.2-1.21.2-1.0-1.1-1.1-1.0
Progressive ratio test 1 inactive lever presses0.80.81.3-1.0-1.1-0.9-0.9-0.8-0.8-0.9-1.0-0.70.7-0.9-1.0-1.1-1.0
Progressive ratio test 2 active lever presses1.01.01.6-1.1-1.2-1.1-1.0-1.0-0.9-1.0-1.1-0.80.7-1.0-1.1-1.2-1.0
Progressive ratio test 2 breakpoint1.51.72.4-1.4-1.5-1.3-1.3-1.3-1.2-1.3-1.4-1.01.0-1.3-1.3-1.5-1.3
Progressive ratio test 2 inactive lever presses0.40.40.7-0.8-0.8-0.7-0.6-0.5-0.5-0.6-0.7-0.50.4-0.6-0.7-0.8-0.7
Total sessions with >9 infusions0.00.00.10.10.10.10.20.20.20.20.20.3-0.30.20.20.10.2
Short access day 1 total inactive lever presses0.00.00.1-0.2-0.3-0.0-0.1-0.1-0.1-0.1-0.10.4-0.4-0.1-0.1-0.3-0.1
Short access day 10 total inactive lever presses0.70.71.1-1.0-1.0-0.8-0.9-1.0-0.8-0.9-0.8-0.30.3-1.0-0.8-0.9-0.9
Short access day 1 total infusions0.50.50.70.60.60.70.70.80.80.70.70.8-0.80.70.70.60.7
Short access day 10 total infusions0.10.10.4-0.10.0-0.20.00.10.00.0-0.2-0.60.60.0-0.2-0.0-0.0
Short access total infusions0.30.40.60.60.70.60.70.70.70.70.50.3-0.30.70.60.60.7
Short access day 1 locomotion0.70.70.90.90.80.80.90.90.90.90.80.7-0.70.90.80.80.9
Short access day 10 total locomotion1.71.92.71.51.61.31.51.51.51.51.30.6-0.51.41.31.51.6
Short access total locomotion2.32.32.61.61.61.51.61.61.61.61.51.3-1.31.51.61.61.6
Compulsive drug intake0.10.10.60.20.10.30.20.10.20.20.40.7-0.70.20.40.10.1
One hour access (0.3 mA shock)0.40.51.20.60.40.70.60.60.70.60.71.1-1.10.60.70.50.6
One hour access (shock baseline)0.20.20.4-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.6-0.60.6-0.5-0.6-0.5-0.4
Number of responses in last shaping day0.10.10.1-0.3-0.4-0.2-0.3-0.2-0.2-0.3-0.20.1-0.1-0.3-0.2-0.3-0.3
Context. condit. distance diff. score0.20.20.5-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.5-0.70.7-0.3-0.6-0.4-0.4
Locomotion velocity, session 10.40.40.7-0.7-0.8-0.4-0.6-0.7-0.8-0.7-0.50.2-0.2-0.8-0.5-0.7-0.7
Locomotion distance, session 12.22.83.2-1.7-1.8-1.6-1.6-1.7-1.8-1.6-1.8-1.41.4-1.7-1.8-1.7-1.7
Locomotion velocity, session 25.15.97.4-2.5-2.7-2.3-2.5-2.6-2.7-2.6-2.4-1.61.5-2.7-2.5-2.5-2.6
Locomotion distance, session 21.21.72.2-1.4-1.5-1.3-1.3-1.4-1.5-1.3-1.4-0.90.9-1.4-1.3-1.4-1.4
Locomotion velocity, session 30.30.40.6-0.7-0.8-0.4-0.6-0.7-0.7-0.7-0.50.2-0.2-0.8-0.5-0.7-0.7
Locomotion distance, session 31.01.11.71.00.91.11.01.01.01.01.21.3-1.31.01.10.91.0
Stereotopy head waving bouts, day 31.41.62.1-1.2-1.3-1.3-1.4-1.3-1.2-1.2-1.4-1.11.1-1.3-1.2-1.3-1.3
Stereotopy head waving duration, day 31.92.32.8-1.6-1.7-1.5-1.7-1.7-1.6-1.6-1.7-1.01.0-1.6-1.4-1.6-1.6
Locomotion velocity, session 70.10.10.2-0.3-0.5-0.1-0.4-0.3-0.3-0.3-0.10.4-0.4-0.3-0.2-0.4-0.3
Locomotion distance, session 70.00.10.2-0.2-0.3-0.0-0.2-0.2-0.2-0.10.00.4-0.4-0.0-0.0-0.2-0.1
Stereotopy head waving bouts, day 70.20.30.4-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.70.6-0.5-0.6-0.5-0.5
Stereotopy head waving duration, day 70.00.00.20.10.2-0.00.10.10.10.1-0.1-0.40.40.1-0.10.10.1
Locomotion velocity, session 80.60.71.0-0.9-0.9-0.7-0.7-0.9-1.0-0.8-0.8-0.60.6-0.9-0.9-0.8-0.9
Locomotion distance, session 81.01.41.8-1.2-1.3-1.1-1.1-1.2-1.3-1.1-1.3-1.21.1-1.1-1.3-1.3-1.1
Degree of sensitization distance1.61.72.1-1.3-1.4-1.3-1.4-1.4-1.4-1.3-1.3-0.90.9-1.2-1.3-1.4-1.3
Degree of sensitization stereotypy0.40.40.50.70.70.60.70.70.70.70.60.2-0.20.70.50.60.7
Condit. Reinf. active minus inactive responses1.71.92.3-1.4-1.4-1.4-1.4-1.5-1.4-1.4-1.2-1.21.2-1.5-1.4-1.4-1.5
Condit. Reinf. active-inactive response ratio0.30.40.5-0.6-0.5-0.7-0.6-0.7-0.6-0.6-0.5-0.70.7-0.6-0.6-0.5-0.6
Condit. Reinf. active responses3.03.64.2-1.9-2.0-1.9-2.0-1.9-1.9-1.9-1.8-1.71.7-2.0-2.0-1.9-2.0
Condit. Reinf. inactive responses2.42.83.2-1.7-1.7-1.6-1.8-1.6-1.6-1.8-1.8-1.61.6-1.7-1.8-1.7-1.7
Incentive salience index mean2.12.53.1-1.6-1.8-1.5-1.7-1.7-1.6-1.7-1.4-1.11.1-1.8-1.6-1.6-1.7
Condit. Reinf. lever presses3.75.06.0-2.3-2.5-2.2-2.4-2.3-2.2-2.4-2.1-1.71.7-2.4-2.3-2.4-2.3
Time in familiar zone, hab. session 10.40.30.6-0.7-0.8-0.4-0.7-0.5-0.5-0.8-0.60.1-0.2-0.7-0.5-0.7-0.7
Time in novel zone, hab. session 10.70.60.90.90.90.60.80.70.71.00.90.5-0.40.90.90.90.9
Total zone transitions, hab. session 14.05.66.5-2.4-2.6-2.4-2.4-2.4-2.4-2.3-2.5-2.12.1-2.3-2.5-2.5-2.4
Total locomotion distance, hab. session 14.05.77.1-2.5-2.7-2.4-2.5-2.5-2.5-2.5-2.3-1.81.7-2.4-2.4-2.5-2.5
Locomotion velocity, hab. session 13.55.06.3-2.3-2.5-2.2-2.3-2.4-2.4-2.3-2.1-1.71.6-2.3-2.3-2.4-2.3
Time in familiar zone, hab. session 21.81.92.61.51.51.41.41.61.61.51.20.7-0.71.61.21.51.5
Time in novel zone, hab. session 20.30.30.5-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.40.0-0.0-0.7-0.3-0.6-0.6
Total zone transitions, hab. session 23.44.46.1-2.0-1.9-2.2-2.0-2.0-2.0-1.9-2.3-2.52.5-2.0-2.2-2.0-2.0
Total locomotion distance, hab. session 23.44.55.0-2.1-2.1-2.2-2.1-2.1-2.1-2.1-2.2-2.22.2-2.1-2.2-2.1-2.1
Locomotion velocity, hab. session 22.73.74.1-1.9-1.9-2.0-1.9-1.9-1.9-1.9-2.0-2.02.0-1.9-2.0-1.9-1.9
Novel to familiar place preference ratio0.10.10.2-0.3-0.3-0.3-0.4-0.3-0.3-0.4-0.3-0.30.3-0.4-0.3-0.4-0.3
Novelty place preference0.00.00.0-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.0-0.00.0-0.1-0.1-0.1-0.1
Time in novel zone, NPP test0.00.00.0-0.0-0.1-0.0-0.1-0.0-0.1-0.10.00.1-0.1-0.1-0.0-0.1-0.0
Total zone transitions, NPP test7.110.111.3-3.2-3.3-3.2-3.1-3.2-3.3-3.1-3.3-3.03.0-3.1-3.4-3.2-3.1
Total locomotion distance, NPP test6.38.79.5-2.9-3.0-3.0-2.9-2.9-3.0-2.9-3.0-2.82.8-3.0-3.1-3.0-2.9
Locomotion velocity, NPP test6.99.911.3-3.1-3.2-3.1-3.1-3.1-3.2-3.1-3.2-3.23.1-3.1-3.4-3.1-3.1
Pavlov. Cond. lever latency1.92.43.51.61.91.41.71.71.61.71.30.9-0.81.71.71.71.6
Pavlov. Cond. magazine entry latency0.40.51.0-0.8-1.0-0.5-0.9-0.8-0.7-0.8-0.50.2-0.3-0.8-0.6-0.8-0.8
Pavlov. Cond. change in total contacts1.51.62.4-1.3-1.6-1.3-1.5-1.4-1.3-1.4-1.1-0.60.6-1.4-1.3-1.5-1.3
Pavlov. Cond. index score1.92.43.7-1.6-1.9-1.4-1.8-1.7-1.6-1.7-1.3-0.70.6-1.7-1.6-1.7-1.7
Pavlov. Cond. latency score1.21.52.5-1.3-1.6-1.0-1.4-1.3-1.3-1.3-0.9-0.30.3-1.4-1.3-1.4-1.3
Pavlov. Cond. lever contacts2.83.34.6-1.9-2.1-1.7-2.0-1.9-1.9-2.0-1.6-1.21.1-1.9-1.9-2.0-1.9
Pavlov. Cond. magazine entry number1.31.62.51.41.61.21.51.41.31.41.10.4-0.41.41.31.41.4
Pavlov. Cond. intertrial magazine entries0.81.01.21.01.10.91.01.01.01.11.00.7-0.71.11.01.01.1
Pavlov. Cond. lever-magazine prob. diff.1.72.13.3-1.6-1.8-1.3-1.7-1.6-1.5-1.6-1.2-0.60.5-1.6-1.5-1.6-1.6
Pavlov. Cond. response bias3.44.25.7-2.1-2.4-2.0-2.3-2.1-2.1-2.2-1.9-1.21.2-2.2-2.1-2.2-2.2
Bone: apparent density0.20.30.50.70.70.40.60.70.70.60.5-0.20.20.70.40.60.7
Bone surface1.11.92.61.51.61.31.51.61.61.51.30.5-0.51.61.21.51.6
Bone volume0.40.71.00.91.00.80.91.00.90.90.80.2-0.21.00.70.91.0
Bone: connectivity density0.50.81.21.01.10.71.01.01.01.00.7-0.20.31.00.71.01.0
Bone: cortical apparent density0.81.01.21.01.01.11.01.00.91.01.11.0-1.01.01.01.01.0
Bone: cortical area0.40.61.1-0.8-1.0-0.5-0.8-0.8-0.8-0.8-0.7-0.30.2-0.7-0.9-0.9-0.8
Bone: cortical porosity0.10.10.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.40.4-0.3-0.3-0.3-0.3
Bone: cortical porosity0.00.00.1-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.30.00.0-0.2-0.1-0.2-0.2
Bone: cortical thickness0.61.01.7-1.1-1.3-0.8-1.1-1.1-1.1-1.1-0.9-0.40.3-1.1-1.1-1.1-1.1
Bone: cortical thickness0.00.00.10.10.10.00.10.10.10.1-0.0-0.30.30.1-0.10.00.1
Bone: cortical tissue density0.70.91.00.90.91.00.90.90.90.91.00.9-1.00.90.90.90.9
Bone: elastic displacement0.20.30.40.50.60.60.50.50.50.50.60.4-0.50.50.50.60.5
Bone: elastic work0.10.10.3-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.50.5-0.2-0.4-0.2-0.2
Bone: endosteal estimation0.40.91.21.01.00.81.01.11.01.00.90.6-0.61.10.90.91.1
Bone: endosteal perimeter0.00.00.00.1-0.00.00.00.10.10.0-0.0-0.10.10.1-0.0-0.00.1
Bone: final force0.30.60.9-0.7-0.9-0.7-0.7-0.7-0.7-0.7-0.7-0.80.8-0.6-1.0-0.8-0.6
Bone: final moment0.20.40.7-0.6-0.8-0.5-0.7-0.6-0.6-0.7-0.6-0.50.4-0.6-0.8-0.8-0.6
Bone: marrow area0.51.01.31.11.10.91.01.11.11.01.00.7-0.71.11.01.01.2
Bone: maximum diameter0.10.20.4-0.4-0.6-0.2-0.5-0.4-0.4-0.5-0.30.1-0.2-0.4-0.4-0.5-0.4
Bone: maximum force0.00.10.4-0.1-0.2-0.2-0.1-0.0-0.1-0.1-0.2-0.60.6-0.0-0.4-0.2-0.0
Bone: maximum moment0.00.00.10.0-0.1-0.0-0.00.0-0.0-0.0-0.0-0.30.20.1-0.2-0.10.1
Bone: minimum diameter0.10.30.5-0.5-0.7-0.5-0.5-0.4-0.5-0.5-0.6-0.40.3-0.4-0.6-0.6-0.4
Bone: periosteal estimation0.00.00.1-0.1-0.2-0.0-0.1-0.0-0.1-0.1-0.10.2-0.2-0.0-0.1-0.2-0.0
Bone: periosteal perimeter0.50.81.2-0.9-1.0-0.8-0.9-0.8-0.9-0.9-0.9-0.80.7-0.8-1.1-1.0-0.8
Bone: post-yield work0.00.00.30.00.0-0.10.00.10.00.0-0.1-0.50.50.1-0.2-0.10.1
Bone: stiffness0.00.00.10.10.10.10.10.20.10.10.0-0.20.20.2-0.10.00.2
Bone: tissue strength0.10.10.20.30.30.40.30.30.20.30.40.4-0.40.30.30.30.3
Bone: trabecular number0.40.60.80.90.80.70.90.90.90.90.70.1-0.20.90.60.80.9
Bone: trabecular spacing0.40.50.8-0.8-0.8-0.6-0.7-0.8-0.9-0.7-0.60.1-0.1-0.8-0.5-0.8-0.8
Bone: trabecular thickness0.60.71.00.91.00.80.91.01.00.90.80.2-0.21.00.70.91.0
Bone: trabecular tissue density0.30.52.30.30.20.60.30.30.30.30.71.5-1.50.30.80.30.3
Breakpoint value in progressive ratio session0.00.00.20.0-0.00.10.1-0.00.10.10.30.4-0.40.10.10.10.0
Distance traveled before self-admin0.10.10.2-0.3-0.4-0.2-0.3-0.2-0.2-0.2-0.3-0.10.10.0-0.3-0.5-0.1
Distance traveled after self-admin3.84.25.1-2.1-2.2-2.1-2.2-2.1-2.2-2.1-2.0-1.61.6-2.0-2.0-2.2-2.0
Delta time in closed arm before/after self-admin0.20.20.7-0.4-0.3-0.5-0.2-0.2-0.4-0.3-0.5-0.80.8-0.3-0.5-0.4-0.2
Delta time in open arm before/after self-admin0.50.40.70.70.60.70.50.50.70.60.60.9-0.80.60.80.50.5
Diff in mean of infusions in LGA sessions0.20.30.5-0.6-0.7-0.5-0.6-0.6-0.6-0.5-0.40.1-0.1-0.6-0.5-0.5-0.6
Extinction: sum of active levers before priming0.00.00.0-0.1-0.1-0.10.0-0.0-0.0-0.00.10.1-0.1-0.00.0-0.1-0.1
Active lever presses in extinction session 60.10.10.3-0.3-0.3-0.1-0.2-0.3-0.2-0.20.20.5-0.5-0.2-0.0-0.1-0.2
Delta distance traveled before/after self-admin5.55.96.9-2.4-2.3-2.5-2.6-2.5-2.6-2.5-2.4-2.22.2-2.6-2.3-2.3-2.5
Delta ambulatory time before/after self-admin4.65.05.8-2.2-2.1-2.3-2.4-2.3-2.4-2.3-2.2-2.02.1-2.4-2.1-2.1-2.3
Time in closed arm before self-admin0.10.10.20.30.50.30.30.30.40.30.2-0.20.20.20.30.40.3
Time in closed arm after self-admin0.10.10.8-0.00.2-0.20.00.10.1-0.0-0.3-0.90.9-0.1-0.20.10.0
Time in open arm before self-admin2.12.23.3-1.6-1.8-1.5-1.5-1.5-1.8-1.5-1.5-0.90.8-1.4-1.6-1.7-1.5
Time in open arm after self-admin0.30.30.7-0.6-0.8-0.5-0.6-0.7-0.7-0.5-0.50.1-0.2-0.6-0.5-0.8-0.7
Sum of active levers in priming session hrs 5-61.31.33.30.90.81.11.00.80.90.91.21.8-1.81.01.20.91.0
Time to tail flick, vehicle, before self-admin0.20.20.60.40.50.60.80.30.60.60.60.4-0.40.20.40.60.3
Time to tail flick, vehicle, after self-admin1.92.03.01.61.71.41.61.41.41.51.30.6-0.61.61.31.61.6
Time to tail flick, test, before self-admin5.95.87.52.32.22.52.32.32.22.42.52.7-2.72.22.52.42.3
Time to tail flick, test, after self-admin0.50.50.90.70.70.70.80.50.60.70.90.6-0.70.60.70.90.8
Delta time to tail flick, vehicle, before/after SA0.40.40.90.80.80.60.60.60.60.50.60.3-0.30.90.60.60.9
Delta time to tail flick, test, before/after SA2.11.94.2-1.2-1.0-1.4-1.1-1.3-1.2-1.2-1.3-2.12.0-1.2-1.5-1.2-1.1
Ambulatory time before self-admin0.10.10.30.20.10.30.20.30.30.20.30.5-0.50.50.20.10.4
Ambulatory time after self-admin3.63.94.7-2.0-2.1-2.0-2.2-2.0-2.1-2.1-2.0-1.61.7-2.0-1.9-2.1-2.0
Total heroin consumption0.00.10.2-0.1-0.3-0.3-0.2-0.1-0.20.1-0.2-0.30.30.2-0.3-0.40.1
Area under the delay curve8.99.510.43.13.03.13.13.03.03.03.23.2-3.23.03.23.03.0
Delay disc. indifference point, 0s delay1.51.62.51.21.21.21.21.11.11.11.41.6-1.51.21.51.21.2
Delay disc. indifference point, 16s delay12.612.813.23.63.53.63.63.53.53.53.63.6-3.63.53.63.63.5
Delay disc. indifference point, 2s delay3.33.64.91.91.81.91.81.81.71.82.12.2-2.21.72.11.91.7
Delay disc. indifference point, 24s delay1.11.11.41.11.11.11.21.01.01.01.10.8-0.91.01.11.21.0
Delay disc. indifference point, 4s delay4.04.27.51.91.62.01.81.91.81.92.12.7-2.71.92.11.71.9
Delay disc. indifference point, 8s delay5.75.96.82.42.32.52.42.42.32.42.52.6-2.62.42.52.32.4
Delay discount exponential model param8.69.110.0-3.1-2.9-3.1-3.0-2.9-2.9-2.9-3.2-3.13.2-3.0-3.1-3.0-3.0
Delay discount hyperbolic model param7.88.39.5-2.9-2.7-2.9-2.8-2.8-2.8-2.8-3.0-3.13.1-2.8-3.0-2.8-2.8
Fecal boli incidents, locomotor time 10.70.71.70.80.50.90.70.70.80.70.91.3-1.30.80.80.70.7
Change in fecal boli incidents, locomotor task0.10.10.40.30.20.30.30.20.20.20.30.6-0.60.20.40.20.2
Time >=10cm from walls, locomotor time 10.20.20.4-0.4-0.6-0.4-0.5-0.4-0.4-0.4-0.40.00.0-0.4-0.4-0.6-0.3
Bouts of movement, locomotor time 10.10.10.20.10.30.10.20.30.30.3-0.0-0.30.40.30.20.10.3
Total resting periods, locomotor time 10.20.20.7-0.4-0.3-0.5-0.3-0.2-0.2-0.3-0.6-0.80.8-0.2-0.3-0.5-0.3
Rest time, locomotor task time 10.90.91.11.00.90.90.91.01.00.91.01.1-1.01.01.10.81.0
Distance moved, locomotor task time 10.10.10.1-0.2-0.1-0.2-0.1-0.3-0.3-0.2-0.2-0.40.4-0.3-0.3-0.2-0.3
Vertical activity count, locomotor time 10.50.60.80.80.80.80.80.70.60.70.90.6-0.70.70.70.90.7
Time >=10cm from walls, locomotor time 20.30.30.6-0.6-0.8-0.6-0.7-0.5-0.5-0.5-0.50.0-0.0-0.5-0.5-0.8-0.6
Bouts of movement, locomotor time 20.40.40.7-0.5-0.6-0.7-0.7-0.6-0.5-0.6-0.8-0.70.7-0.6-0.7-0.7-0.5
Total resting periods, locomotor time 20.10.10.3-0.2-0.2-0.4-0.4-0.2-0.2-0.2-0.5-0.50.5-0.3-0.4-0.4-0.1
Rest time, locomotor task time 20.60.71.00.90.90.70.81.01.00.90.70.4-0.41.00.80.81.0
Distance moved, locomotor task time 21.11.21.7-1.2-1.1-1.1-1.0-1.1-1.1-1.1-1.1-0.90.9-1.2-1.0-1.2-1.3
Vertical activity count, locomotor time 20.20.20.50.30.30.40.40.20.20.20.60.7-0.70.30.40.40.3
Weight adjusted by age0.20.20.4-0.5-0.5-0.5-0.4-0.6-0.4-0.5-0.4-0.20.2-0.6-0.4-0.6-0.6
Seeking ratio, delayed vs. immediate footshock2.12.43.11.61.61.51.61.51.61.81.51.1-1.11.51.51.61.7
Locomotion in novel chamber0.91.11.21.11.01.11.11.11.01.11.11.0-1.01.11.01.01.1
Locomotion in novel chamber post-restriction1.82.23.91.31.21.51.51.41.21.31.62.0-2.01.31.51.21.4
Progressive ratio0.60.60.80.90.80.90.80.90.80.80.90.6-0.60.90.70.90.8
Food seeking constrained by brief footshock0.10.10.2-0.2-0.2-0.2-0.4-0.3-0.2-0.2-0.2-0.50.4-0.3-0.3-0.1-0.2
Seeking ratio, punishment vs. effort0.60.70.9-0.9-0.8-0.8-0.9-0.9-0.9-0.8-0.8-0.60.7-1.0-0.7-0.9-0.9
Run reversals in cocaine runway, females0.40.40.8-0.7-0.9-0.6-0.4-0.7-0.8-0.7-0.6-0.30.2-0.7-0.8-0.8-0.7
Run reversals in cocaine runway, males0.00.00.1-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.20.1-0.1-0.1-0.1-0.2-0.1
Latency to leave start box in cocaine runway1.61.82.3-1.5-1.5-1.3-1.4-1.4-1.4-1.4-1.3-0.90.9-1.4-1.4-1.4-1.3
Latency to leave start box in cocaine runway, F0.20.20.3-0.5-0.4-0.4-0.5-0.5-0.4-0.4-0.5-0.50.5-0.4-0.4-0.4-0.4
Latency to leave start box in cocaine runway, M4.24.15.3-2.2-2.3-2.0-2.1-2.1-2.1-2.1-1.9-1.21.2-2.1-2.0-2.2-2.1
Cd content in liver1.21.42.11.11.11.21.11.11.11.11.11.5-1.41.11.31.11.1
Co content in liver0.00.00.1-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.10.00.0-0.2-0.0-0.2-0.2
Cu content in liver0.81.02.10.90.71.00.80.80.80.91.21.4-1.40.81.00.80.8
Fe content in liver0.50.60.70.70.70.80.80.90.90.80.70.5-0.50.80.60.80.8
K content in liver0.30.30.50.60.70.30.60.60.60.60.2-0.60.60.60.30.60.6
Mg content in liver1.92.02.31.51.51.51.51.51.51.41.41.0-1.11.51.31.41.5
Mn content in liver1.01.11.5-1.1-0.9-1.2-1.1-1.0-1.0-1.1-1.0-1.01.1-1.0-0.9-1.1-1.0
Na content in liver0.00.00.1-0.2-0.3-0.1-0.2-0.2-0.2-0.2-0.0-0.20.1-0.2-0.3-0.2-0.2
Rb content in liver6.88.59.63.02.93.13.03.03.03.03.12.5-2.63.02.82.93.0
Se content in liver0.10.10.1-0.4-0.4-0.3-0.4-0.3-0.3-0.4-0.40.1-0.1-0.4-0.2-0.4-0.4
Sr content in liver0.70.60.7-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.8-0.30.4-0.9-0.7-0.9-0.9
Zn content in liver5.76.38.82.42.32.62.42.42.42.32.53.0-3.02.42.62.32.4