Dgat2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016573 0.45 0.12 0.0e+00 0.26 0.33 0.32 0.32 1.6e-28 4.5e-37 1.2e-36 8.6e-37
2 Adipose intron excision ratio chr1:153465152:153469531 0.08 0.07 4.2e-06 0.04 0.03 0.04 0.04 4.2e-05 1.2e-04 5.6e-05 5.2e-05
3 Adipose mRNA stability ENSRNOG00000016573 0.04 0.03 3.1e-03 0 0 0.01 0 2.2e-01 8.1e-02 7.0e-02 1.1e-01
4 BLA gene expression ENSRNOG00000016573 0.42 0.16 5.0e-16 0.18 0.28 0.23 0.29 3.9e-10 1.7e-15 1.9e-12 6.1e-16
5 Brain gene expression ENSRNOG00000016573 0.28 0.11 0.0e+00 0.26 0.27 0.28 0.28 6.1e-24 1.1e-24 1.2e-25 8.2e-26
6 IL gene expression ENSRNOG00000016573 0.4 0.2 8.9e-04 0.03 0.03 0.02 0.02 7.7e-02 5.5e-02 1.2e-01 9.2e-02
7 LHb gene expression ENSRNOG00000016573 0.31 0.16 8.3e-05 0.02 0.1 0.08 0.06 8.9e-02 2.9e-03 7.2e-03 2.0e-02
8 Liver gene expression ENSRNOG00000016573 0.15 0.09 1.4e-10 0.03 0.08 0.07 0.07 1.2e-04 6.1e-09 1.0e-08 1.7e-08
9 NAcc gene expression ENSRNOG00000016573 0.3 0.18 7.8e-13 0.16 0.17 0.16 0.17 1.3e-11 1.8e-12 3.3e-12 1.8e-12
10 OFC gene expression ENSRNOG00000016573 0.27 0.14 2.3e-04 0.15 0.12 0.07 0.12 2.3e-04 7.2e-04 1.2e-02 1.1e-03
11 PL gene expression ENSRNOG00000016573 0.38 0.16 0.0e+00 0.26 0.29 0.29 0.3 4.9e-20 1.4e-22 2.1e-22 6.1e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.00.10.20.4-0.10.50.40.20.5-0.30.40.30.40.3
BMI without tail0.81.66.4-0.11.32.50.2-0.30.6-2.50.20.81.6-0.5
Body weight0.31.55.70.21.02.40.4-0.20.9-2.20.40.91.6-0.1
Epididymis fat weight0.92.03.81.3-0.22.01.50.91.7-0.81.41.61.91.2
Glucose0.00.00.20.1-0.2-0.4-0.3-0.2-0.10.4-0.0-0.1-0.20.0
Heart weight1.01.42.3-1.41.4-0.4-1.3-1.5-1.3-0.9-1.3-1.2-1.0-1.2
Left kidney weight0.61.76.4-1.01.81.4-1.1-1.4-0.5-2.5-0.9-0.40.3-1.4
Right kidney weight0.41.04.2-0.71.31.4-0.7-1.0-0.2-2.0-0.5-0.10.5-0.9
Tail length1.64.819.8-1.13.03.5-0.8-1.6-0.0-4.4-0.80.31.6-1.9
Length with tail0.72.49.3-0.11.73.00.0-0.60.7-3.00.11.01.8-0.7
Length without tail0.30.61.20.9-1.1-0.60.60.70.61.10.70.4-0.00.9
Liver weight, left1.11.74.21.1-0.42.01.10.71.5-0.61.31.72.00.9
Liver weight, right3.05.09.32.1-1.13.02.21.72.7-0.52.32.73.01.9
Parametrial fat weight0.71.33.21.0-0.21.81.00.51.4-0.51.11.41.60.8
Retroperitoneal fat weight4.013.323.73.7-1.54.93.72.74.4-0.93.94.34.73.0
Intraocular pressure0.81.22.3-1.00.4-1.4-1.0-1.0-1.30.3-1.1-1.4-1.5-0.8
Extensor digitorum longus weight0.20.83.40.30.51.90.80.30.8-1.20.50.81.20.1
Soleus weight0.61.97.50.60.72.70.90.51.3-1.80.81.32.00.2
Tibialis anterior weight0.10.31.5-0.40.90.9-0.2-0.5-0.1-1.2-0.3-0.20.2-0.5
Tibia length2.05.78.3-2.41.7-2.5-2.6-2.3-2.8-0.5-2.6-2.8-2.9-2.3
Number of licking bursts4.85.77.32.7-2.21.42.52.42.71.62.72.62.22.7
Food consumed during 24 hour testing period2.02.44.0-2.01.2-0.7-2.0-1.6-1.8-1.2-1.8-1.4-1.2-1.8
Times rat made contact with spout0.80.92.50.6-0.11.60.70.81.0-0.60.81.21.40.5
Mean time between licks in bursts3.04.211.1-1.92.71.1-2.2-2.4-1.3-3.3-1.8-1.1-0.3-2.4
Mean num. licks in bursts3.84.66.4-2.52.2-0.9-2.3-2.1-2.4-1.8-2.4-2.2-1.8-2.5
Std. dev. time between licks in bursts0.91.04.1-0.61.31.2-1.0-0.9-0.1-2.0-0.5-0.10.5-1.2
Water consumed over 24 hours1.11.32.11.0-1.20.71.21.51.10.81.21.41.21.1
Indifference point 0 sec5.89.411.9-3.43.4-1.1-3.3-3.4-3.2-2.6-3.4-3.1-2.5-3.4
Indifference point AUC0.20.20.8-0.00.60.9-0.0-0.30.2-0.9-0.00.20.5-0.1
Indifference point function ln k1.82.64.3-1.60.9-2.0-1.7-1.3-1.9-0.0-1.7-1.9-2.1-1.6
Indifference point function log k1.82.64.3-1.60.9-2.0-1.7-1.3-1.9-0.0-1.7-1.9-2.1-1.6
Delay discounting total patch changes 0 sec4.77.59.8-3.03.1-1.0-2.9-3.1-2.8-2.4-3.0-2.8-2.3-3.0
Delay discounting total patch changes 12 sec1.52.04.4-1.42.00.7-1.3-1.6-1.1-2.1-1.3-1.0-0.4-1.5
Delay discounting total patch changes 18 sec1.82.44.5-1.72.00.5-1.5-1.7-1.3-2.1-1.6-1.1-0.6-1.8
Delay discounting total patch changes 24 sec0.30.40.9-0.50.80.1-0.7-0.9-0.4-1.0-0.6-0.5-0.3-0.6
Delay discounting total patch changes 6 sec1.62.43.7-1.71.8-0.7-1.6-1.9-1.7-1.0-1.7-1.7-1.4-1.4
Delay discounting time to switch 0 sec4.06.09.02.7-3.00.32.72.92.42.52.62.31.62.7
Delay discounting water rate 0 sec3.45.37.4-2.62.5-0.9-2.5-2.7-2.4-1.9-2.6-2.4-1.9-2.4
Delay discounting water rate 12 sec2.23.34.4-2.01.6-1.2-2.0-2.1-2.0-1.0-2.0-1.9-1.7-1.9
Delay discounting water rate 18 sec0.71.01.6-1.01.2-0.2-1.1-1.2-0.9-1.0-1.0-0.9-0.6-1.2
Delay discounting water rate 24 sec1.52.03.2-1.40.8-1.8-1.5-1.3-1.70.1-1.4-1.7-1.8-1.3
Delay discounting water rate 6 sec1.01.41.9-1.31.0-1.0-1.3-1.3-1.4-0.3-1.3-1.3-1.3-1.2
Locomotor activity0.91.42.0-1.41.4-0.1-1.3-1.4-1.2-1.1-1.2-0.9-0.8-1.4
Locomotor testing distance1.93.24.8-2.02.2-0.0-1.9-2.1-1.7-2.0-1.8-1.4-1.1-2.1
Locomotor testing rearing0.61.03.5-0.91.51.0-0.8-1.0-0.5-1.9-0.7-0.30.1-1.1
Light reinforcement 11.93.54.32.0-1.71.32.02.02.01.12.02.11.92.0
Light reinforcement 20.10.10.30.2-0.5-0.20.20.20.10.60.20.20.10.3
Reaction time number correct0.30.41.6-0.4-0.4-1.3-0.6-0.2-0.70.8-0.4-0.5-0.9-0.1
Reaction time mean minus median0.91.22.3-1.21.50.4-1.1-1.5-0.9-1.3-1.1-0.8-0.4-1.2
Reaction time mean minus median AUC1.21.52.4-1.41.4-0.2-1.3-1.5-1.2-1.1-1.3-1.1-0.8-1.4
Reaction time num false alarms2.12.93.71.9-1.51.41.91.81.90.71.91.91.81.7
Reaction time num false alarms AUC1.41.92.41.6-1.40.81.51.51.50.81.51.61.31.4
Reaction time trials correct on left0.30.41.6-0.4-0.4-1.3-0.6-0.2-0.70.8-0.4-0.5-0.9-0.1
Reaction time trials on left0.30.41.6-0.4-0.4-1.3-0.6-0.2-0.70.8-0.4-0.5-0.9-0.1
Reaction time mean0.50.71.10.8-0.31.01.00.51.00.10.90.91.00.9
Reaction time mean AUC0.91.21.71.2-0.81.01.30.91.30.51.21.21.21.2
Median of all reaction times1.11.42.11.3-0.90.91.41.01.40.61.31.31.21.4
Reaction time omissions0.10.10.30.4-0.10.30.2-0.00.50.00.40.30.40.5
Reaction time false alarm rate1.72.43.21.7-1.21.31.81.61.80.51.71.71.71.5
Reaction time premature initiation rate1.82.47.4-1.32.41.4-1.2-1.7-0.7-2.7-1.1-0.70.1-1.6
Reaction time premature initiations1.52.14.2-1.52.10.4-1.6-1.7-1.1-2.0-1.4-1.0-0.6-1.6
Std. dev. reaction times0.40.51.7-0.41.11.0-0.3-0.8-0.0-1.3-0.3-0.10.4-0.6
Reaction time trials completed0.30.41.6-0.4-0.4-1.3-0.6-0.2-0.70.8-0.4-0.5-0.9-0.1
Reaction time trials AUC0.20.31.2-0.3-0.3-1.1-0.6-0.3-0.60.7-0.4-0.5-0.8-0.1
Social response proportion0.91.01.30.9-0.71.01.11.11.10.21.01.21.11.0
Social responses1.11.42.91.1-0.41.71.11.01.4-0.41.21.51.70.9
Social time3.34.36.22.3-2.40.12.32.51.92.32.21.81.22.5
Conditioned locomotion0.10.10.2-0.1-0.2-0.5-0.1-0.0-0.20.5-0.1-0.2-0.30.1
Cocaine response after cond. corrected2.12.33.51.9-1.40.91.61.41.80.91.71.61.41.9
Cocaine response after cond. not corrected0.70.81.51.1-0.90.10.90.81.00.81.00.80.61.2
Cocaine response before conditioning1.31.52.3-1.50.9-1.1-1.3-1.0-1.5-0.3-1.4-1.3-1.3-1.3
Saline control response1.01.42.8-1.31.50.2-1.0-1.3-1.0-1.7-1.2-1.0-0.6-1.3
Condit. Reinf. active minus inactive responses5.56.810.2-2.83.1-0.4-2.8-3.2-2.5-2.8-2.8-2.5-1.8-2.9
Condit. Reinf. active-inactive response ratio1.01.11.6-1.01.0-0.7-1.0-1.1-1.1-0.8-1.2-1.3-1.1-1.0
Condit. Reinf. active responses7.19.915.5-3.43.90.1-3.4-3.9-2.8-3.8-3.3-2.7-1.7-3.5
Condit. Reinf. inactive responses4.15.110.1-2.42.90.9-2.5-2.9-1.7-3.2-2.2-1.4-0.6-2.6
Condit. Reinf. lever presses17.424.034.2-5.45.5-1.4-5.5-5.8-4.9-4.4-5.4-4.8-3.7-5.4
Condit. Reinf. lever reinforcers received8.211.517.8-3.64.1-0.2-3.8-4.2-3.1-3.8-3.6-3.0-2.0-3.8
Pavlov. Cond. lever latency18.625.534.35.6-5.51.95.65.95.24.25.65.14.15.5
Pavlov. Cond. magazine entry latency6.37.29.0-3.02.7-1.7-2.9-2.9-2.9-1.6-3.0-3.0-2.7-2.7
Pavlov. Cond. change in total contacts13.618.925.0-4.74.5-2.3-4.9-5.0-4.6-3.2-4.8-4.6-3.9-4.6
Pavlov. Cond. index score15.620.326.2-5.04.8-2.1-5.0-5.1-4.7-3.5-5.0-4.7-4.0-4.8
Pavlov. Cond. latency score14.518.323.6-4.74.5-2.1-4.8-4.9-4.5-3.2-4.8-4.5-3.9-4.6
Pavlov. Cond. lever contacts19.927.737.9-5.85.7-2.0-5.9-6.2-5.4-4.4-5.8-5.3-4.3-5.7
Pavlov. Cond. magazine entry number8.510.513.23.5-3.12.33.43.43.61.93.63.63.33.3
Pavlov. Cond. intertrial magazine entries0.70.93.40.60.11.90.50.20.9-1.10.71.11.50.2
Pavlov. Cond. lever-magazine prob. diff.14.218.423.8-4.74.6-2.0-4.7-4.9-4.5-3.4-4.8-4.5-3.8-4.6
Pavlov. Cond. response bias20.628.437.7-5.95.8-2.2-5.9-6.1-5.5-4.3-5.9-5.4-4.5-5.8
Conditioned reinforcement - actives2.62.64.2-1.61.0-1.7-1.7-1.6-1.9-0.3-1.7-1.9-2.1-1.5
Conditioned reinforcement - inactives0.60.71.11.0-0.90.50.80.60.90.60.90.90.71.1
Conditioned locomotion1.82.14.2-1.40.6-1.9-1.4-1.4-1.70.3-1.5-1.7-2.0-1.1
Intermittent access intake day 1-15 change1.81.82.4-1.30.9-1.3-1.6-1.5-1.4-0.3-1.4-1.4-1.6-1.3
Intermittent access intake escalation2.32.23.0-1.51.1-1.4-1.7-1.7-1.6-0.4-1.6-1.6-1.7-1.5
Intermittent access intake escalation 20.70.71.2-0.80.8-0.4-0.9-1.1-0.8-0.6-0.9-0.8-0.8-0.9
Intermitt. access day 1 inactive lever presses0.80.81.21.0-0.80.51.00.91.00.61.00.90.91.1
Intermitt. access day 15 inactive lever presses0.10.10.30.1-0.5-0.30.20.4-0.00.60.10.1-0.20.3
Intermitt. access escalation Index0.10.10.3-0.50.50.1-0.2-0.3-0.4-0.4-0.4-0.3-0.0-0.2
Intermittent access day 1 total infusions0.40.51.0-0.80.90.5-0.7-1.0-0.5-1.0-0.6-0.3-0.1-0.7
Intermittent access day 15 total infusions1.82.03.5-1.51.2-0.9-1.7-1.9-1.5-0.7-1.5-1.3-1.4-1.4
Intermittent access terminal intake (last 3 days)1.31.42.8-1.31.2-0.4-1.4-1.7-1.2-0.8-1.3-1.0-1.0-1.3
Intermittent access total infusions0.50.51.3-0.80.8-0.0-0.8-1.1-0.7-0.7-0.8-0.5-0.5-0.8
Intermittent access day 1 locomotion0.00.00.1-0.1-0.1-0.2-0.1-0.2-0.20.3-0.1-0.1-0.20.0
Intermittent access day 15 total locomotion1.31.42.0-1.30.8-1.0-1.3-1.4-1.4-0.3-1.3-1.2-1.3-1.2
Intermittent access total locomotion0.30.40.9-0.70.6-0.2-0.6-0.9-0.7-0.4-0.7-0.5-0.5-0.6
Intermittent access standard deviation0.00.00.2-0.10.20.3-0.1-0.3-0.0-0.4-0.10.10.0-0.2
Cocaine induced anxiety2.02.44.31.6-1.70.51.82.11.51.21.61.41.21.6
Post-drug Anxiety0.60.61.10.8-0.80.40.81.10.90.50.80.80.70.8
Baseline Anxiety2.02.13.4-1.51.6-0.5-1.7-1.8-1.3-1.3-1.5-1.3-1.1-1.6
Lifetime Intake0.70.81.8-1.01.0-0.2-1.0-1.3-0.9-0.7-1.0-0.8-0.7-1.0
Incentive Sensitization - Responses2.52.53.8-1.71.9-0.2-1.6-1.9-1.5-1.7-1.7-1.4-1.1-1.8
Incentive Sensitization - Breakpoint2.52.53.7-1.71.8-0.4-1.6-1.9-1.6-1.6-1.7-1.5-1.2-1.8
Progressive ratio test 1 active lever presses0.30.30.50.7-0.70.10.60.40.50.70.60.50.20.7
Progressive ratio test 1 breakpoint0.20.30.40.7-0.60.20.50.30.50.60.60.50.20.6
Progressive ratio test 1 inactive lever presses0.10.10.2-0.20.40.2-0.2-0.4-0.2-0.3-0.2-0.2-0.1-0.2
Progressive ratio test 2 active lever presses1.01.12.0-1.01.2-0.2-1.0-1.4-1.0-1.0-1.1-0.9-0.8-1.2
Progressive ratio test 2 breakpoint1.01.11.9-1.11.3-0.1-1.1-1.4-1.0-1.1-1.1-0.9-0.8-1.2
Progressive ratio test 2 inactive lever presses0.40.50.8-0.90.8-0.1-0.7-0.9-0.8-0.5-0.8-0.7-0.6-0.7
Total sessions with >9 infusions2.73.04.1-1.91.6-1.1-2.0-1.9-1.9-0.9-1.9-1.8-1.8-1.9
Short access day 1 total inactive lever presses0.30.30.60.7-0.70.30.50.30.60.60.70.70.50.8
Short access day 10 total inactive lever presses0.10.10.30.4-0.4-0.10.40.40.20.50.30.20.10.4
Short access day 1 total infusions1.92.03.8-1.51.6-0.2-1.6-2.0-1.4-1.3-1.5-1.2-1.0-1.5
Short access day 10 total infusions0.50.51.1-0.70.90.1-0.8-1.1-0.6-1.0-0.7-0.5-0.4-0.8
Short access total infusions0.50.61.3-0.81.00.1-0.9-1.1-0.6-0.9-0.7-0.5-0.4-0.9
Short access day 1 locomotion2.83.05.3-1.61.0-2.1-1.9-1.7-1.90.0-1.8-2.1-2.3-1.5
Short access day 10 total locomotion0.30.30.4-0.50.5-0.3-0.5-0.6-0.6-0.4-0.6-0.6-0.5-0.6
Short access total locomotion0.20.20.4-0.30.2-0.5-0.5-0.5-0.40.1-0.4-0.5-0.6-0.4
Compulsive drug intake0.30.31.2-0.3-0.1-1.1-0.3-0.0-0.50.5-0.4-0.7-0.9-0.2
One hour access (0.3 mA shock)1.82.12.8-1.71.5-0.6-1.4-1.7-1.6-1.1-1.6-1.5-1.3-1.6
One hour access (shock baseline)1.01.22.2-1.21.2-0.1-1.1-1.5-1.1-1.0-1.2-1.0-0.8-1.2
Number of responses in last shaping day0.30.31.3-0.40.81.0-0.1-0.2-0.0-1.1-0.20.10.5-0.4
Context. condit. distance diff. score3.84.66.5-2.32.1-1.8-2.1-2.0-2.4-0.9-2.4-2.5-2.5-2.1
Locomotion velocity, session 10.50.51.60.5-1.1-1.00.40.80.21.30.40.3-0.30.5
Locomotion distance, session 10.70.92.4-0.70.3-1.5-0.8-0.5-1.00.3-0.9-1.1-1.5-0.6
Locomotion velocity, session 20.00.00.10.2-0.3-0.0-0.00.20.2-0.00.20.30.2-0.1
Locomotion distance, session 20.20.20.4-0.50.2-0.5-0.6-0.4-0.6-0.1-0.5-0.5-0.5-0.5
Locomotion velocity, session 30.70.81.9-0.80.3-1.4-0.7-0.5-1.10.2-0.9-1.2-1.3-0.7
Locomotion distance, session 31.41.52.9-1.20.4-1.7-1.2-0.9-1.50.2-1.3-1.5-1.6-1.0
Stereotopy head waving bouts, day 30.60.71.20.8-0.51.00.80.80.9-0.10.81.01.10.7
Stereotopy head waving duration, day 30.20.30.4-0.60.5-0.4-0.6-0.5-0.6-0.2-0.6-0.5-0.5-0.6
Locomotion velocity, session 70.20.20.50.3-0.6-0.50.50.60.20.70.3-0.0-0.10.6
Locomotion distance, session 70.00.00.10.3-0.20.00.30.20.20.10.20.10.10.3
Stereotopy head waving bouts, day 71.61.82.5-1.51.0-1.2-1.5-1.2-1.6-0.6-1.6-1.5-1.3-1.4
Stereotopy head waving duration, day 72.12.53.6-1.91.4-0.9-1.9-1.7-1.8-1.2-1.8-1.6-1.3-1.8
Locomotion velocity, session 81.62.02.7-1.61.6-0.6-1.6-1.7-1.4-1.0-1.5-1.3-1.1-1.6
Locomotion distance, session 82.23.24.5-1.91.6-1.6-1.8-1.6-2.0-0.8-2.0-2.1-2.1-1.8
Degree of sensitization distance1.11.13.60.80.11.90.80.31.2-0.90.91.21.50.6
Degree of sensitization stereotypy4.04.36.1-2.31.6-1.7-2.5-2.1-2.4-1.0-2.4-2.2-2.1-2.2
Condit. Reinf. active minus inactive responses0.30.31.1-0.30.70.9-0.3-0.4-0.0-1.1-0.20.10.4-0.4
Condit. Reinf. active-inactive response ratio0.80.92.7-0.81.41.1-0.7-0.9-0.4-1.6-0.6-0.30.2-1.0
Condit. Reinf. active responses0.10.10.50.10.00.70.00.10.3-0.40.20.40.60.0
Condit. Reinf. inactive responses0.20.20.70.5-0.8-0.20.30.60.30.60.50.30.30.5
Incentive salience index mean0.20.21.0-0.30.60.7-0.3-0.3-0.1-1.0-0.20.00.3-0.5
Condit. Reinf. lever presses0.00.10.3-0.20.10.2-0.20.1-0.1-0.5-0.2-0.00.1-0.3
Time in familiar zone, hab. session 10.20.20.60.3-0.20.60.30.50.5-0.30.40.60.80.1
Time in novel zone, hab. session 10.00.00.10.3-0.00.20.2-0.10.20.10.20.10.10.4
Total zone transitions, hab. session 10.30.51.1-0.60.1-1.0-0.7-0.6-0.80.5-0.6-0.8-1.0-0.5
Total locomotion distance, hab. session 11.11.52.71.2-0.61.61.31.11.5-0.31.31.41.51.1
Locomotion velocity, hab. session 10.60.81.60.9-0.41.31.00.81.0-0.30.91.01.10.8
Time in familiar zone, hab. session 21.31.42.7-1.31.60.4-1.2-1.2-0.9-1.6-1.1-0.7-0.2-1.6
Time in novel zone, hab. session 20.60.61.60.8-1.1-0.70.60.50.41.30.60.2-0.21.1
Total zone transitions, hab. session 21.82.34.1-1.50.9-1.7-1.6-1.4-1.7-0.1-1.6-1.8-2.0-1.2
Total locomotion distance, hab. session 20.40.51.90.40.11.40.50.30.7-0.90.50.70.90.4
Locomotion velocity, hab. session 20.50.72.30.60.01.50.70.50.9-0.80.70.91.10.6
Novel to familiar place preference ratio0.10.10.4-0.1-0.1-0.60.1-0.1-0.20.2-0.2-0.4-0.60.0
Novelty place preference0.10.10.30.0-0.2-0.50.30.0-0.10.3-0.1-0.3-0.50.2
Time in novel zone, NPP test0.10.10.4-0.2-0.0-0.60.0-0.2-0.30.1-0.3-0.5-0.7-0.1
Total zone transitions, NPP test0.20.31.0-0.4-0.0-1.0-0.5-0.4-0.60.5-0.5-0.6-0.8-0.2
Total locomotion distance, NPP test1.31.82.41.5-1.01.21.51.31.60.21.41.51.41.5
Locomotion velocity, NPP test1.82.63.51.9-1.31.31.81.61.90.51.81.81.61.8
Pavlov. Cond. lever latency0.91.12.01.2-1.2-0.31.20.91.01.41.10.70.41.4
Pavlov. Cond. magazine entry latency2.53.24.5-2.12.1-0.1-1.8-1.8-1.7-2.1-1.9-1.6-1.2-2.1
Pavlov. Cond. change in total contacts0.60.71.1-0.90.8-0.1-1.0-0.8-0.8-1.0-0.9-0.7-0.5-1.0
Pavlov. Cond. index score2.12.75.1-1.92.00.3-1.7-1.6-1.5-2.3-1.7-1.3-0.8-2.1
Pavlov. Cond. latency score2.22.84.7-1.92.00.2-1.8-1.6-1.6-2.2-1.8-1.3-0.8-2.1
Pavlov. Cond. lever contacts0.70.92.6-1.01.00.6-1.0-0.7-0.7-1.6-0.9-0.4-0.1-1.3
Pavlov. Cond. magazine entry number3.03.75.22.2-2.20.22.12.11.92.12.11.81.32.3
Pavlov. Cond. intertrial magazine entries2.12.54.31.8-2.10.31.61.71.51.61.71.61.21.8
Pavlov. Cond. lever-magazine prob. diff.1.72.14.2-1.71.70.4-1.6-1.4-1.3-2.0-1.5-1.1-0.6-1.8
Pavlov. Cond. response bias0.70.82.4-1.01.00.6-0.9-0.7-0.7-1.5-0.9-0.5-0.2-1.2
Bone: apparent density0.10.10.6-0.20.10.80.1-0.00.0-0.00.10.40.50.2
Bone surface1.22.13.9-1.72.00.6-1.4-1.8-1.3-1.7-1.5-1.0-0.5-1.6
Bone volume0.61.02.0-1.21.40.9-0.8-1.1-0.8-1.4-0.9-0.4-0.0-1.1
Bone: connectivity density0.20.30.8-0.90.70.1-0.6-0.6-0.7-0.2-0.6-0.5-0.3-0.5
Bone: cortical apparent density1.62.03.21.5-1.01.51.41.31.70.41.61.81.71.3
Bone: cortical area0.60.82.0-0.91.40.7-0.7-1.2-0.6-1.4-0.8-0.5-0.2-0.9
Bone: cortical porosity1.41.52.6-1.10.6-1.6-1.3-1.1-1.40.0-1.3-1.5-1.6-1.1
Bone: cortical porosity0.91.02.2-0.90.3-1.5-1.0-0.8-1.10.2-1.0-1.2-1.4-0.8
Bone: cortical thickness0.10.10.30.3-0.20.30.50.30.30.30.40.40.30.5
Bone: cortical thickness0.20.20.6-0.40.2-0.7-0.2-0.3-0.50.2-0.5-0.6-0.8-0.0
Bone: cortical tissue density1.62.13.21.5-1.11.51.41.41.70.41.61.81.71.3
Bone: elastic displacement1.21.42.41.3-1.3-0.21.41.21.11.51.31.00.51.5
Bone: elastic work1.31.63.21.2-1.6-0.41.51.51.01.81.21.00.41.6
Bone: endosteal estimation1.02.16.1-1.42.11.0-1.3-1.6-0.8-2.5-1.2-0.7-0.1-1.7
Bone: endosteal perimeter1.63.36.9-1.92.40.7-1.9-2.2-1.4-2.6-1.7-1.2-0.6-2.2
Bone: final force0.10.10.5-0.40.60.4-0.3-0.7-0.2-0.3-0.3-0.1-0.0-0.2
Bone: final moment0.20.30.8-0.60.90.5-0.5-0.9-0.4-0.6-0.5-0.2-0.0-0.5
Bone: marrow area0.81.85.5-1.22.01.1-1.1-1.4-0.7-2.3-1.0-0.50.0-1.5
Bone: maximum diameter2.13.86.8-2.12.60.3-2.0-2.5-1.7-2.4-2.0-1.5-1.0-2.2
Bone: maximum force0.30.50.9-0.81.00.3-0.7-0.9-0.6-0.7-0.7-0.5-0.3-0.7
Bone: maximum moment0.40.71.5-1.01.20.3-0.8-1.1-0.7-0.9-0.9-0.5-0.3-0.9
Bone: minimum diameter0.61.14.3-0.31.32.0-0.1-0.60.3-2.1-0.10.41.0-0.6
Bone: periosteal estimation1.02.15.4-1.52.10.9-1.3-1.7-0.9-2.3-1.3-0.8-0.3-1.6
Bone: periosteal perimeter1.52.55.3-1.72.10.8-1.6-1.9-1.2-2.3-1.5-0.9-0.4-1.9
Bone: post-yield work0.60.81.4-1.11.20.3-1.0-1.1-0.8-0.9-0.9-0.7-0.4-1.0
Bone: stiffness0.10.21.00.20.21.00.2-0.10.5-0.40.20.50.60.2
Bone: tissue strength0.50.52.1-0.1-0.6-1.4-0.10.1-0.51.3-0.2-0.6-1.00.2
Bone: trabecular number0.40.60.90.6-0.80.60.90.90.60.90.80.80.71.0
Bone: trabecular spacing0.91.11.9-0.90.5-1.3-1.2-1.1-1.1-0.3-1.1-1.3-1.4-1.0
Bone: trabecular thickness0.40.51.90.30.11.40.70.50.6-0.40.60.91.10.5
Bone: trabecular tissue density1.52.13.51.6-0.81.71.41.11.9-0.11.61.71.81.2
Breakpoint value in progressive ratio session0.20.20.50.4-0.7-0.40.30.50.30.70.40.2-0.00.5
Distance traveled before self-admin0.50.50.80.7-0.50.60.90.80.80.40.70.80.60.8
Distance traveled after self-admin1.21.43.21.0-1.5-0.41.31.40.71.81.00.80.21.5
Delta time in closed arm before/after self-admin1.31.34.20.8-0.02.10.90.71.3-1.00.91.31.70.5
Delta time in open arm before/after self-admin2.22.13.0-1.61.70.1-1.5-1.7-1.4-1.5-1.5-1.4-1.0-1.6
Diff in mean of infusions in LGA sessions3.23.54.72.1-1.90.92.22.22.01.42.11.91.62.1
Extinction: sum of active levers before priming0.40.40.60.6-0.60.50.80.70.60.10.60.60.60.7
Active lever presses in extinction session 64.34.18.2-2.01.1-2.6-2.0-1.6-2.30.0-2.1-2.5-2.9-1.8
Delta distance traveled before/after self-admin0.20.20.7-0.3-0.3-0.8-0.20.0-0.50.6-0.3-0.5-0.7-0.0
Delta ambulatory time before/after self-admin0.40.51.6-0.3-0.4-1.3-0.30.1-0.70.9-0.4-0.7-1.1-0.0
Time in closed arm before self-admin1.82.04.2-1.50.4-2.1-1.4-1.1-1.80.5-1.4-1.6-1.8-1.0
Time in closed arm after self-admin0.50.51.60.5-1.1-0.40.60.80.31.30.50.50.20.7
Time in open arm before self-admin3.13.35.12.3-1.70.91.92.02.21.12.12.01.61.9
Time in open arm after self-admin0.50.62.2-0.31.21.1-0.4-0.80.0-1.5-0.3-0.10.3-0.6
Sum of active levers in priming session hrs 5-60.10.10.30.1-0.4-0.10.50.50.10.20.20.20.10.4
Time to tail flick, vehicle, before self-admin0.20.20.7-0.0-0.20.80.50.40.1-0.10.30.40.70.3
Time to tail flick, vehicle, after self-admin2.12.33.0-1.71.4-1.0-1.7-1.6-1.7-0.8-1.7-1.6-1.6-1.6
Time to tail flick, test, before self-admin0.20.20.6-0.20.60.6-0.3-0.4-0.0-0.8-0.2-0.00.2-0.5
Time to tail flick, test, after self-admin0.20.20.80.10.70.7-0.2-0.30.2-0.90.00.20.4-0.4
Delta time to tail flick, vehicle, before/after SA2.92.84.9-1.41.2-1.9-1.9-1.7-1.6-0.4-1.7-1.9-2.2-1.6
Delta time to tail flick, test, before/after SA0.20.20.40.7-0.5-0.30.40.50.50.60.50.30.10.5
Ambulatory time before self-admin0.60.71.00.8-0.90.01.01.00.70.90.80.70.51.0
Ambulatory time after self-admin1.41.54.81.0-1.6-0.91.31.50.52.20.90.6-0.21.5
Total heroin consumption0.10.10.2-0.40.2-0.4-0.3-0.2-0.4-0.1-0.4-0.4-0.4-0.3
Area under the delay curve0.00.00.00.1-0.1-0.2-0.1-0.00.1-0.1-0.0-0.1-0.1-0.1
Delay disc. indifference point, 0s delay0.40.40.7-0.70.5-0.3-0.8-0.7-0.6-0.7-0.7-0.6-0.5-0.8
Delay disc. indifference point, 16s delay0.10.10.30.3-0.5-0.50.10.30.20.50.20.0-0.20.3
Delay disc. indifference point, 2s delay0.80.91.3-0.70.8-0.7-1.1-1.1-0.7-0.8-1.0-1.1-1.0-1.1
Delay disc. indifference point, 24s delay1.11.11.71.0-0.80.81.31.11.00.61.11.11.11.3
Delay disc. indifference point, 4s delay0.10.10.5-0.10.2-0.0-0.4-0.4-0.1-0.7-0.3-0.2-0.1-0.6
Delay disc. indifference point, 8s delay0.30.30.4-0.60.5-0.3-0.7-0.6-0.5-0.4-0.6-0.6-0.6-0.7
Delay discount exponential model param0.00.00.0-0.20.20.1-0.0-0.1-0.2-0.0-0.1-0.00.0-0.0
Delay discount hyperbolic model param0.00.00.1-0.0-0.00.10.20.1-0.00.20.10.10.10.2
Fecal boli incidents, locomotor time 10.70.81.3-1.10.6-0.9-0.9-0.8-1.2-0.1-1.0-1.0-1.1-0.7
Change in fecal boli incidents, locomotor task1.31.31.81.3-1.30.21.31.31.21.01.21.00.81.3
Time >=10cm from walls, locomotor time 12.22.23.7-1.51.0-1.6-1.5-1.4-1.7-0.3-1.6-1.9-1.9-1.4
Bouts of movement, locomotor time 10.00.00.1-0.1-0.1-0.3-0.1-0.0-0.20.1-0.2-0.2-0.3-0.0
Total resting periods, locomotor time 10.10.10.4-0.0-0.4-0.60.00.2-0.20.6-0.0-0.2-0.40.3
Rest time, locomotor task time 10.60.61.50.7-1.2-0.70.70.90.51.10.60.4-0.00.9
Distance moved, locomotor task time 10.70.82.4-0.71.41.1-0.6-1.0-0.3-1.5-0.5-0.10.3-1.0
Vertical activity count, locomotor time 11.31.42.9-1.11.70.5-1.1-1.4-0.8-1.5-1.1-0.8-0.3-1.5
Time >=10cm from walls, locomotor time 20.70.70.9-0.90.8-0.6-0.9-0.9-0.9-0.7-1.0-1.0-0.9-0.9
Bouts of movement, locomotor time 20.20.20.5-0.40.6-0.0-0.6-0.5-0.3-0.7-0.5-0.5-0.3-0.6
Total resting periods, locomotor time 20.10.10.2-0.10.3-0.1-0.3-0.2-0.1-0.4-0.3-0.3-0.3-0.3
Rest time, locomotor task time 22.32.73.71.8-1.70.61.91.81.71.51.81.61.31.9
Distance moved, locomotor task time 22.63.04.5-1.82.0-0.3-1.9-2.0-1.6-1.9-1.8-1.6-1.2-2.1
Vertical activity count, locomotor time 21.71.93.7-1.41.80.5-1.3-1.6-1.1-1.9-1.3-1.0-0.4-1.8
Weight adjusted by age0.50.52.2-0.51.01.0-0.4-0.5-0.2-1.5-0.4-0.10.3-0.8
Seeking ratio, delayed vs. immediate footshock1.92.23.31.5-1.70.61.81.61.31.51.61.50.91.8
Locomotion in novel chamber1.31.62.3-1.40.7-1.5-1.4-1.1-1.50.0-1.3-1.5-1.5-1.2
Locomotion in novel chamber post-restriction4.14.87.7-2.11.5-2.6-2.3-1.9-2.4-0.3-2.3-2.8-2.7-2.1
Progressive ratio0.20.20.6-0.4-0.0-0.8-0.3-0.1-0.50.3-0.4-0.6-0.6-0.2
Food seeking constrained by brief footshock1.01.22.5-1.11.50.2-1.1-1.5-0.8-1.6-1.1-0.8-0.4-1.2
Seeking ratio, punishment vs. effort0.60.72.5-0.51.21.0-0.6-1.0-0.2-1.6-0.5-0.10.3-0.8
Run reversals in cocaine runway, females2.22.18.30.80.62.90.90.31.4-1.81.01.52.20.3
Run reversals in cocaine runway, males0.00.00.00.1-0.00.20.10.00.10.10.10.20.20.1
Latency to leave start box in cocaine runway2.12.33.92.0-1.60.61.51.61.91.01.71.51.21.5
Latency to leave start box in cocaine runway, F1.71.83.21.8-1.20.91.31.31.80.41.51.51.31.3
Latency to leave start box in cocaine runway, M0.20.20.80.4-0.7-0.50.20.50.20.90.30.1-0.10.4
Cd content in liver0.80.91.50.9-0.41.21.01.01.1-0.20.91.11.20.9
Co content in liver0.70.82.9-0.81.30.7-0.7-0.5-0.5-1.7-0.7-0.40.1-1.2
Cu content in liver0.20.31.4-0.30.50.6-0.4-0.3-0.1-1.2-0.30.00.3-0.7
Fe content in liver0.00.00.20.2-0.00.10.40.30.20.00.20.10.20.2
K content in liver0.30.30.60.5-0.30.70.50.40.6-0.20.50.70.80.2
Mg content in liver0.20.20.2-0.40.4-0.2-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.5
Mn content in liver1.21.43.61.2-1.7-0.71.11.20.81.91.10.70.21.4
Na content in liver0.50.61.1-0.60.3-1.0-0.9-0.7-0.80.1-0.7-0.9-1.0-0.7
Rb content in liver0.81.01.9-1.21.30.3-1.0-1.0-0.9-1.4-1.0-0.7-0.3-1.4
Se content in liver4.75.68.72.6-3.00.32.52.82.32.42.52.31.62.7
Sr content in liver0.10.10.4-0.1-0.2-0.7-0.00.1-0.30.5-0.1-0.3-0.50.0
Zn content in liver4.95.47.1-2.62.5-0.9-2.5-2.6-2.5-2.1-2.6-2.3-1.9-2.7