Hub : Genes

Ctsc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000022342 0.16 0.07 0.0e+00 0.14 0.17 0.16 0.16 9.6e-16 2.8e-18 6.0e-18 9.8e-18
2 Adipose alternative polyA ENSRNOT00000097085 0.17 0.07 0.0e+00 0.13 0.19 0.19 0.19 6.1e-14 1.5e-20 2.1e-20 2.0e-20
3 Adipose gene expression ENSRNOG00000016496 0.73 0.07 0.0e+00 0.69 0.7 0.7 0.69 1.6e-106 1.7e-107 3.5e-109 7.8e-107
4 Adipose isoform ratio ENSRNOT00000022342 0.16 0.08 0.0e+00 0.1 0.16 0.16 0.15 9.6e-11 4.3e-17 5.8e-17 2.6e-16
5 Adipose isoform ratio ENSRNOT00000097085 0.18 0.08 0.0e+00 0.11 0.18 0.18 0.18 3.0e-12 1.3e-19 3.4e-19 4.2e-19
6 Adipose intron excision ratio chr1:142031177:142036233 0.05 0.03 2.6e-05 0.03 0.04 0.03 0.03 1.5e-04 6.5e-05 5.8e-04 1.5e-04
7 Adipose intron excision ratio chr1:142031177:142045569 0.04 0.03 2.5e-04 0.01 0.02 0.01 0.01 1.6e-02 4.7e-03 7.6e-03 1.4e-02
8 BLA alternative polyA ENSRNOT00000022342 0.07 0.06 7.2e-03 0 0.01 0.01 0 3.4e-01 5.1e-02 9.8e-02 2.7e-01
9 BLA alternative polyA ENSRNOT00000097085 0.07 0.05 8.6e-03 0 0.02 0.01 0 2.8e-01 3.2e-02 7.6e-02 1.6e-01
10 BLA gene expression ENSRNOG00000016496 0.12 0.08 3.1e-05 0.1 0.07 0.07 0.08 5.0e-06 1.6e-04 8.8e-05 5.8e-05
11 BLA mRNA stability ENSRNOG00000016496 0.05 0.04 8.6e-03 0.03 0.01 -0 0 1.5e-02 1.1e-01 4.0e-01 2.0e-01
12 Brain gene expression ENSRNOG00000016496 0.23 0.09 0.0e+00 0.27 0.31 0.3 0.3 1.7e-25 4.5e-29 6.3e-28 1.3e-28
13 Brain isoform ratio ENSRNOT00000022342 0.03 0.02 1.5e-03 0.04 0.03 0.03 0.03 1.7e-04 9.7e-04 1.2e-03 4.1e-04
14 Eye gene expression ENSRNOG00000016496 0.29 0.17 5.8e-03 0.15 0.08 0.11 0.12 2.9e-03 2.3e-02 8.5e-03 8.0e-03
15 IL gene expression ENSRNOG00000016496 0.3 0.21 4.8e-04 0.16 0.09 0.06 0.13 1.0e-04 3.5e-03 1.3e-02 5.8e-04
16 LHb gene expression ENSRNOG00000016496 0.17 0.1 1.1e-03 0.08 0.03 0.03 0.04 6.2e-03 5.5e-02 8.0e-02 3.2e-02
17 LHb mRNA stability ENSRNOG00000016496 0.17 0.13 8.9e-03 0.09 0.07 0.04 0.09 3.4e-03 1.2e-02 3.1e-02 3.5e-03
18 Liver gene expression ENSRNOG00000016496 0.46 0.17 0.0e+00 0.24 0.28 0.27 0.26 1.1e-26 1.0e-30 4.6e-30 1.3e-28
19 Liver mRNA stability ENSRNOG00000016496 0.05 0.03 2.6e-06 0.04 0.04 0.03 0.03 3.4e-05 1.8e-05 1.2e-04 1.6e-04
20 NAcc gene expression ENSRNOG00000016496 0.12 0.07 4.1e-09 0.09 0.12 0.1 0.1 4.0e-07 3.3e-09 6.5e-08 1.3e-07
21 OFC gene expression ENSRNOG00000016496 0.14 0.1 8.2e-03 0.05 0.04 0.01 0.03 2.4e-02 4.3e-02 1.7e-01 5.9e-02
22 PL gene expression ENSRNOG00000016496 0.14 0.07 9.9e-11 0.11 0.12 0.13 0.12 6.7e-09 1.6e-09 8.2e-10 3.0e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
BMI with tail0.10.41.60.6-0.5-0.60.5-0.5-0.50.5-0.00.1-0.60.6-0.60.5-0.1-0.6-0.70.5-1.00.6-0.5-0.6-1.3
BMI without tail0.10.20.4-0.50.40.4-0.50.50.4-0.50.2-0.3-0.20.10.30.10.60.30.5-0.5-0.3-0.30.30.5-0.5
Body weight0.00.10.2-0.40.40.5-0.30.30.3-0.30.1-0.10.10.20.40.00.5-0.10.3-0.50.2-0.40.30.3-0.4
Epididymis fat weight0.61.32.91.1-1.1-0.41.2-1.2-1.31.21.5-1.5-1.41.2-1.01.1-1.7-1.4-0.70.70.21.0-1.4-0.8-1.1
Glucose0.30.51.2-0.50.60.0-0.60.60.6-0.6-1.00.90.8-0.90.4-0.90.90.90.2-0.3-0.1-0.40.70.11.1
Heart weight0.30.41.6-0.10.2-0.5-0.20.30.3-0.2-1.21.30.8-0.80.0-0.81.00.8-0.50.4-0.90.00.4-0.50.2
Left kidney weight1.64.58.32.1-2.2-1.22.2-2.2-2.32.22.1-2.0-2.12.9-2.02.9-2.3-2.6-1.71.6-1.11.9-2.4-1.7-2.1
Right kidney weight0.10.21.20.3-0.30.20.3-0.4-0.40.30.8-0.8-0.30.9-0.21.1-0.4-0.7-0.0-0.10.10.1-0.40.0-0.5
Tail length0.10.31.5-0.30.20.7-0.30.20.0-0.21.2-1.2-0.40.60.20.7-0.1-0.30.8-0.60.3-0.3-0.10.6-0.2
Length with tail0.20.62.2-0.80.71.3-0.70.60.6-0.70.8-0.90.3-0.10.80.00.10.01.1-1.11.5-0.90.41.00.6
Length without tail0.10.20.9-0.30.40.4-0.30.30.4-0.3-0.30.30.7-0.60.5-0.60.20.20.2-0.30.9-0.50.40.20.6
Liver weight, left0.50.72.50.6-0.60.40.7-0.7-0.70.71.2-1.2-0.71.6-0.31.6-1.3-1.10.1-0.11.00.2-0.70.1-0.7
Liver weight, right1.42.46.71.0-1.10.41.2-1.3-1.41.22.6-2.6-1.82.5-0.82.4-2.0-2.2-0.10.00.80.7-1.5-0.0-1.5
Parametrial fat weight0.50.92.0-0.80.90.5-0.90.91.0-0.9-1.31.21.1-1.20.8-1.41.21.10.7-0.70.6-0.81.10.70.9
Retroperitoneal fat weight1.34.26.52.1-2.1-1.22.2-2.2-2.32.22.1-2.0-2.42.4-2.02.2-2.5-2.5-1.71.7-0.51.9-2.3-1.6-2.0
Intraocular pressure6.99.720.5-2.72.90.7-2.93.13.3-2.9-4.54.53.9-3.92.6-4.04.34.21.3-1.1-0.2-2.43.51.32.7
Extensor digitorum longus weight0.00.10.4-0.40.40.4-0.30.40.4-0.4-0.20.20.3-0.20.4-0.10.70.10.3-0.4-0.2-0.40.40.5-0.2
Soleus weight0.10.20.60.4-0.4-0.20.4-0.4-0.40.40.2-0.2-0.20.8-0.40.8-0.1-0.6-0.20.2-0.60.3-0.4-0.2-0.4
Tibialis anterior weight0.00.10.40.3-0.1-0.10.3-0.2-0.10.2-0.40.40.30.50.00.60.3-0.4-0.0-0.0-0.60.00.0-0.0-0.5
Tibia length0.82.33.9-1.71.71.2-1.81.81.7-1.7-0.80.81.6-1.51.5-1.41.81.71.2-1.30.8-1.61.61.22.0
Number of licking bursts0.50.63.0-0.0-0.10.70.1-0.2-0.30.11.7-1.7-0.91.0-0.00.9-0.8-0.80.6-0.60.9-0.1-0.50.6-0.2
Food consumed during 24 hour testing period2.32.76.3-1.81.72.3-1.71.61.5-1.70.6-0.70.9-0.91.9-0.90.80.82.2-2.22.5-2.01.42.31.4
Times rat made contact with spout0.80.91.9-1.11.01.4-1.01.00.9-1.00.6-0.70.2-0.11.0-0.30.40.51.3-1.31.4-1.10.71.40.8
Mean time between licks in bursts6.89.512.43.2-3.3-2.63.2-3.2-3.43.32.4-2.2-3.53.1-3.43.1-3.2-3.3-2.92.9-2.53.3-3.5-2.9-3.0
Mean num. licks in bursts0.70.82.2-0.70.80.1-0.80.90.9-0.8-1.51.51.2-1.20.7-1.21.21.30.2-0.2-0.1-0.61.00.20.7
Std. dev. time between licks in bursts2.32.74.71.5-1.6-0.71.6-1.7-1.81.62.1-2.1-2.12.1-1.52.0-2.2-2.1-1.01.0-0.31.4-1.9-1.0-1.5
Water consumed over 24 hours1.92.23.5-1.71.71.8-1.61.61.6-1.6-0.20.11.2-0.81.7-0.91.21.21.8-1.81.8-1.81.51.91.3
Indifference point 0 sec0.40.61.50.9-0.8-1.10.8-0.8-0.70.8-0.30.4-0.40.5-0.80.5-0.5-0.3-1.21.2-1.00.8-0.7-1.1-0.7
Indifference point AUC0.80.92.0-1.11.01.4-1.01.00.9-1.00.4-0.50.2-0.41.1-0.50.60.41.4-1.31.4-1.10.81.40.5
Indifference point function ln k0.91.35.1-0.60.7-0.3-0.70.80.9-0.7-2.22.21.7-1.60.6-1.71.31.7-0.10.1-0.3-0.51.1-0.11.0
Indifference point function log k0.91.35.1-0.60.7-0.3-0.70.80.9-0.7-2.22.21.7-1.60.6-1.71.31.7-0.10.1-0.3-0.51.1-0.11.0
Delay discounting total patch changes 0 sec0.30.51.60.7-0.7-1.10.7-0.6-0.50.6-0.70.7-0.20.2-0.70.1-0.3-0.0-1.21.3-1.00.8-0.5-1.1-0.6
Delay discounting total patch changes 12 sec1.52.03.91.2-1.2-0.31.3-1.3-1.41.32.0-1.9-1.91.9-1.11.7-1.8-2.0-0.60.80.11.0-1.5-0.6-1.6
Delay discounting total patch changes 18 sec2.23.05.11.6-1.7-1.21.7-1.7-1.81.71.8-1.7-2.31.9-1.71.9-2.0-2.0-1.51.4-0.91.6-2.0-1.4-2.0
Delay discounting total patch changes 24 sec1.62.02.91.5-1.5-1.21.5-1.5-1.51.51.0-0.9-1.61.7-1.51.4-1.4-1.5-1.41.5-1.31.5-1.6-1.4-1.5
Delay discounting total patch changes 6 sec0.10.20.5-0.40.30.7-0.30.30.3-0.30.6-0.6-0.10.20.50.2-0.0-0.20.6-0.40.7-0.50.20.6-0.0
Delay discounting time to switch 0 sec4.26.518.41.8-2.0-0.12.0-2.2-2.52.14.3-4.3-3.33.5-1.83.7-3.3-3.6-0.50.50.51.6-2.7-0.5-2.1
Delay discounting water rate 0 sec2.64.213.8-1.31.5-0.1-1.51.71.9-1.6-3.73.72.8-2.71.4-2.92.62.80.4-0.3-0.5-1.22.20.31.4
Delay discounting water rate 12 sec6.39.428.8-2.02.3-0.0-2.32.52.9-2.4-5.45.44.2-4.12.1-4.44.04.20.6-0.5-0.7-1.83.30.62.6
Delay discounting water rate 18 sec13.818.340.3-3.53.81.1-3.84.04.4-3.9-6.46.35.6-5.63.5-5.95.65.61.8-1.70.1-3.24.81.93.6
Delay discounting water rate 24 sec4.36.012.0-2.02.21.0-2.12.32.6-2.2-3.53.43.3-3.12.2-3.22.73.01.4-1.40.9-2.12.81.52.2
Delay discounting water rate 6 sec3.95.615.1-1.72.00.4-1.92.12.3-2.0-3.93.93.2-3.31.9-3.42.93.20.8-0.70.2-1.72.60.82.0
Locomotor activity3.25.08.8-2.22.31.3-2.42.42.4-2.3-2.12.12.4-2.72.1-2.92.73.01.5-1.60.9-2.02.41.42.8
Locomotor testing distance1.01.64.5-1.01.0-0.1-1.11.21.2-1.1-1.91.91.3-1.80.8-2.01.62.10.1-0.2-0.3-0.71.2-0.01.6
Locomotor testing rearing0.60.92.9-0.70.7-0.2-0.80.90.9-0.8-1.41.40.8-1.60.5-1.71.21.40.0-0.1-0.4-0.40.9-0.11.2
Light reinforcement 18.114.724.23.7-3.9-2.13.9-4.0-4.23.94.1-4.0-4.44.9-3.64.8-4.6-4.7-2.62.6-1.53.5-4.3-2.7-3.9
Light reinforcement 216.922.235.04.9-5.0-3.25.1-5.2-5.25.14.1-3.9-4.75.8-4.65.9-5.6-5.7-3.73.8-2.24.5-5.3-3.6-4.7
Reaction time number correct2.13.17.1-1.41.50.4-1.51.61.8-1.5-2.72.62.5-2.31.4-2.22.12.30.5-0.80.4-1.42.00.61.6
Reaction time mean minus median0.20.30.70.4-0.5-0.40.3-0.4-0.50.40.7-0.7-0.80.2-0.60.2-0.5-0.5-0.60.5-0.40.6-0.6-0.5-0.2
Reaction time mean minus median AUC0.30.31.30.5-0.5-0.90.4-0.4-0.40.5-0.20.3-0.4-0.1-0.7-0.0-0.0-0.3-0.90.9-1.10.7-0.5-0.8-0.4
Reaction time num false alarms9.112.622.93.2-3.4-1.63.4-3.5-3.83.54.5-4.4-4.44.6-3.34.8-4.3-4.3-2.12.2-1.33.1-4.1-2.2-3.2
Reaction time num false alarms AUC7.09.718.12.8-3.0-1.42.9-3.1-3.33.04.0-3.9-3.94.0-2.94.3-3.9-3.7-1.81.9-1.02.7-3.6-1.9-2.8
Reaction time trials correct on left2.13.17.1-1.41.50.4-1.51.61.8-1.5-2.72.62.5-2.31.4-2.22.12.30.5-0.80.4-1.42.00.61.6
Reaction time trials on left2.13.07.1-1.41.50.4-1.51.61.8-1.5-2.72.62.5-2.31.4-2.22.12.30.4-0.80.4-1.31.90.61.6
Reaction time mean1.31.83.21.2-1.3-0.61.3-1.3-1.41.31.8-1.7-1.61.6-1.21.6-1.7-1.8-0.80.8-0.51.2-1.5-0.7-0.9
Reaction time mean AUC0.60.92.20.7-0.8-0.20.8-0.9-1.00.81.5-1.5-1.21.1-0.81.1-1.3-1.4-0.40.4-0.20.7-1.1-0.3-0.5
Median of all reaction times1.62.24.21.3-1.4-0.51.4-1.5-1.61.42.1-2.0-1.81.9-1.31.9-2.0-2.1-0.70.8-0.31.2-1.7-0.6-1.1
Reaction time omissions0.10.20.30.3-0.4-0.30.3-0.3-0.40.30.6-0.5-0.60.1-0.40.1-0.4-0.4-0.50.4-0.40.4-0.5-0.4-0.1
Reaction time false alarm rate8.912.722.43.2-3.4-1.53.4-3.5-3.83.54.6-4.5-4.54.6-3.24.7-4.4-4.4-1.92.1-1.13.1-4.1-2.0-3.2
Reaction time premature initiation rate0.10.10.2-0.40.40.4-0.30.30.4-0.4-0.20.20.3-0.30.4-0.30.30.40.5-0.30.3-0.40.40.40.3
Reaction time premature initiations1.01.42.8-1.01.10.4-1.01.11.2-1.1-1.71.71.6-1.51.0-1.51.41.60.5-0.50.3-1.01.30.51.0
Std. dev. reaction times0.10.21.00.0-0.20.00.0-0.1-0.30.11.0-1.0-0.80.2-0.30.2-0.3-0.4-0.10.1-0.20.3-0.40.00.1
Reaction time trials completed2.13.07.1-1.41.50.4-1.51.61.8-1.5-2.72.62.5-2.31.4-2.22.12.30.4-0.80.4-1.31.90.61.6
Reaction time trials AUC1.82.66.1-1.31.40.4-1.41.51.7-1.4-2.52.42.4-2.11.3-2.02.02.20.4-0.70.4-1.31.80.61.4
Social response proportion0.10.10.5-0.10.1-0.2-0.10.20.2-0.1-0.70.70.3-0.70.0-0.70.20.5-0.10.3-0.0-0.00.2-0.10.3
Social responses0.20.21.20.2-0.1-0.70.1-0.10.10.1-1.11.10.4-0.6-0.2-0.60.20.5-0.40.6-0.60.20.1-0.40.4
Social time0.91.24.3-0.70.61.7-0.50.40.3-0.51.8-1.9-0.20.60.90.6-0.7-0.51.6-1.62.1-1.00.21.60.6
Conditioned locomotion2.02.44.21.7-1.7-2.01.7-1.6-1.61.7-0.20.3-1.00.9-1.81.2-1.2-0.9-2.02.0-1.91.8-1.5-2.0-1.5
Cocaine response after cond. corrected0.50.51.3-0.80.71.2-0.70.70.6-0.70.6-0.60.2-0.00.8-0.20.30.01.1-1.11.1-0.80.51.10.4
Cocaine response after cond. not corrected0.50.51.0-0.80.81.0-0.80.80.7-0.80.1-0.10.5-0.50.9-0.40.60.31.0-1.00.9-0.90.71.00.5
Cocaine response before conditioning0.10.10.20.4-0.4-0.30.4-0.4-0.40.40.2-0.1-0.30.2-0.40.3-0.4-0.3-0.40.4-0.10.4-0.4-0.4-0.4
Saline control response0.50.71.5-1.00.91.2-0.90.90.8-0.90.5-0.60.1-0.61.0-0.70.50.41.1-1.20.9-1.00.71.20.5
Condit. Reinf. active minus inactive responses0.60.74.50.4-0.4-1.20.3-0.2-0.20.3-1.31.40.2-0.4-0.6-0.20.80.4-1.01.0-2.10.7-0.0-1.0-0.5
Condit. Reinf. active-inactive response ratio1.41.45.60.9-0.7-1.90.7-0.6-0.40.7-2.02.10.5-0.4-0.9-0.10.60.3-1.61.6-2.41.0-0.2-1.6-0.5
Condit. Reinf. active responses0.30.53.80.1-0.1-0.8-0.00.10.10.0-1.11.20.4-0.3-0.3-0.21.00.5-0.60.7-1.90.40.2-0.7-0.5
Condit. Reinf. inactive responses0.30.30.8-0.70.60.9-0.70.60.5-0.60.8-0.8-0.2-0.00.6-0.10.40.10.8-0.80.4-0.60.30.8-0.0
Condit. Reinf. lever presses0.91.25.60.10.1-1.2-0.10.30.4-0.2-2.32.41.1-1.1-0.1-1.11.41.1-0.90.9-2.10.30.6-0.90.0
Condit. Reinf. lever reinforcers received0.30.43.00.00.1-0.7-0.10.20.2-0.1-1.21.20.5-0.5-0.1-0.31.00.5-0.50.5-1.70.20.3-0.5-0.4
Pavlov. Cond. lever latency1.42.07.0-0.90.82.2-0.70.60.4-0.72.4-2.6-0.60.71.10.8-0.6-0.61.9-1.92.6-1.20.21.90.5
Pavlov. Cond. magazine entry latency0.40.52.10.4-0.3-0.90.3-0.2-0.00.2-1.41.40.5-0.7-0.3-0.70.40.3-0.80.8-1.00.40.1-0.8-0.2
Pavlov. Cond. change in total contacts0.91.36.00.9-0.8-1.70.7-0.6-0.50.7-1.61.70.2-0.2-0.9-0.10.40.0-1.51.5-2.41.0-0.3-1.5-1.0
Pavlov. Cond. index score1.01.35.20.6-0.5-1.70.5-0.3-0.20.4-2.22.30.7-0.9-0.7-0.80.70.6-1.51.5-2.20.80.0-1.5-0.5
Pavlov. Cond. latency score0.91.24.90.6-0.4-1.60.4-0.3-0.10.4-2.12.20.7-0.9-0.6-0.90.70.6-1.41.4-1.90.70.1-1.4-0.3
Pavlov. Cond. lever contacts1.01.35.60.5-0.3-1.60.3-0.10.00.3-2.32.40.8-1.1-0.6-1.10.90.9-1.41.4-2.10.70.2-1.3-0.1
Pavlov. Cond. magazine entry number1.01.25.90.2-0.30.90.3-0.5-0.60.42.4-2.4-1.31.5-0.21.5-1.3-1.20.6-0.61.30.0-0.80.6-0.2
Pavlov. Cond. intertrial magazine entries0.50.71.5-0.90.81.2-0.90.80.6-0.81.0-1.1-0.20.00.7-0.10.30.41.1-1.11.1-0.80.41.10.7
Pavlov. Cond. lever-magazine prob. diff.1.01.24.50.7-0.5-1.70.5-0.4-0.20.5-2.02.10.5-0.8-0.7-0.70.60.5-1.51.5-2.10.9-0.0-1.4-0.5
Pavlov. Cond. response bias1.01.46.20.4-0.3-1.60.2-0.10.10.2-2.42.50.9-1.1-0.5-1.11.10.9-1.41.4-2.30.70.3-1.3-0.2
Conditioned reinforcement - actives1.31.34.11.0-0.9-1.70.9-0.8-0.70.9-1.31.40.4-0.1-1.10.10.30.0-1.81.7-2.01.2-0.5-1.8-0.7
Conditioned reinforcement - inactives1.31.42.91.3-1.3-1.21.3-1.3-1.31.30.7-0.6-1.41.1-1.31.0-1.1-1.3-1.31.0-1.01.3-1.3-1.1-1.7
Conditioned locomotion3.64.39.42.3-2.2-2.82.1-2.1-2.02.1-0.60.7-0.71.1-2.41.3-0.9-1.1-3.13.0-2.92.5-1.8-3.0-1.4
Intermittent access intake day 1-15 change0.80.81.61.0-0.9-1.31.0-0.9-0.70.9-1.11.10.20.5-0.80.6-0.2-0.4-1.21.2-1.20.9-0.5-1.1-0.8
Intermittent access intake escalation1.31.22.81.2-1.0-1.61.2-1.0-0.81.1-1.31.40.30.4-1.10.5-0.1-0.3-1.71.6-1.61.1-0.6-1.6-0.7
Intermittent access intake escalation 21.11.12.41.2-1.1-1.41.2-1.1-0.91.1-1.01.10.40.6-1.00.7-0.4-0.4-1.61.5-1.31.0-0.7-1.5-0.3
Intermitt. access day 1 inactive lever presses3.84.16.0-2.32.32.3-2.32.32.2-2.3-0.40.21.1-1.82.3-1.61.71.72.4-2.42.3-2.42.12.41.2
Intermitt. access day 15 inactive lever presses0.50.51.0-0.80.80.8-0.80.80.8-0.8-0.30.20.8-0.70.8-0.50.60.80.8-1.00.7-0.80.80.70.2
Intermitt. access escalation Index0.40.40.9-0.70.60.9-0.60.60.5-0.60.4-0.50.2-0.40.7-0.60.10.30.9-0.80.9-0.70.50.90.7
Intermittent access day 1 total infusions2.12.44.61.7-1.7-1.81.6-1.6-1.61.60.4-0.3-1.21.0-1.81.3-1.0-1.2-2.11.9-2.01.9-1.6-2.1-1.3
Intermittent access day 15 total infusions3.64.08.22.2-2.1-2.72.1-2.0-1.92.1-0.60.8-0.71.1-2.31.4-1.0-1.2-2.92.7-2.82.3-1.8-2.8-1.7
Intermittent access terminal intake (last 3 days)5.56.011.02.7-2.7-3.02.6-2.6-2.52.6-0.10.3-1.31.7-2.82.1-1.5-1.7-3.33.1-3.12.8-2.3-3.3-2.2
Intermittent access total infusions4.34.78.42.4-2.4-2.62.3-2.2-2.22.30.20.0-1.21.5-2.51.9-1.4-1.6-2.92.7-2.72.5-2.1-2.9-2.1
Intermittent access day 1 locomotion0.10.10.3-0.10.1-0.2-0.20.20.2-0.2-0.60.60.5-0.40.0-0.30.60.4-0.30.1-0.60.00.2-0.3-0.1
Intermittent access day 15 total locomotion0.70.83.70.2-0.1-1.00.10.00.20.0-1.91.91.1-0.5-0.2-0.41.00.8-1.00.9-1.40.30.4-1.0-0.3
Intermittent access total locomotion0.20.31.00.2-0.2-0.60.2-0.1-0.10.2-0.80.90.7-0.1-0.3-0.00.40.3-0.80.6-1.00.4-0.0-0.8-0.5
Intermittent access standard deviation3.84.05.52.3-2.2-2.22.3-2.2-2.12.20.5-0.3-1.21.9-2.12.2-1.7-1.9-2.32.3-1.92.1-2.0-2.3-2.0
Cocaine induced anxiety1.11.22.4-1.31.21.4-1.21.21.1-1.20.4-0.50.5-0.71.2-0.80.60.81.4-1.41.5-1.31.01.41.1
Post-drug Anxiety1.11.21.8-1.31.21.1-1.41.31.1-1.30.2-0.30.0-1.01.1-1.30.91.11.3-1.01.1-1.11.01.31.1
Baseline Anxiety2.42.55.1-1.41.50.4-1.51.61.7-1.5-2.22.21.9-2.01.3-2.12.22.20.8-0.7-0.0-1.21.80.81.5
Lifetime Intake5.96.610.62.9-2.8-3.02.8-2.7-2.72.80.4-0.2-1.72.0-2.92.3-1.9-2.1-3.33.0-3.13.0-2.6-3.2-2.6
Incentive Sensitization - Responses1.11.11.61.1-1.1-0.91.1-1.1-1.11.10.7-0.7-1.21.1-1.21.1-0.9-1.2-1.31.1-0.91.2-1.2-1.2-0.7
Incentive Sensitization - Breakpoint1.31.31.91.2-1.2-1.01.2-1.2-1.21.20.6-0.5-1.21.1-1.31.1-0.9-1.2-1.41.2-1.11.3-1.2-1.4-0.7
Progressive ratio test 1 active lever presses0.80.92.61.0-0.9-1.20.9-0.8-0.80.9-0.50.6-0.00.4-1.00.6-0.1-0.5-1.31.2-1.61.1-0.7-1.3-1.1
Progressive ratio test 1 breakpoint0.70.72.20.9-0.8-1.10.8-0.7-0.70.8-0.50.60.00.4-0.90.6-0.1-0.4-1.21.0-1.50.9-0.6-1.2-1.0
Progressive ratio test 1 inactive lever presses0.30.41.90.5-0.5-0.90.5-0.5-0.40.5-0.30.3-0.50.2-0.60.4-0.1-0.2-0.80.5-0.90.6-0.4-0.8-1.4
Progressive ratio test 2 active lever presses1.51.63.61.3-1.3-1.61.2-1.2-1.21.3-0.20.3-0.50.7-1.50.8-0.5-0.9-1.91.6-1.91.5-1.2-1.9-1.0
Progressive ratio test 2 breakpoint1.51.73.41.4-1.4-1.51.3-1.3-1.31.30.00.1-0.70.9-1.51.0-0.7-1.1-1.81.6-1.81.5-1.2-1.8-1.1
Progressive ratio test 2 inactive lever presses1.11.33.71.1-1.0-1.71.0-0.9-0.81.0-0.91.0-0.20.1-1.20.2-0.0-0.3-1.81.5-1.91.3-0.8-1.9-0.9
Total sessions with >9 infusions5.76.210.42.7-2.7-2.52.6-2.6-2.62.61.0-0.8-2.12.5-2.72.7-2.1-2.3-2.62.6-2.62.7-2.6-2.6-3.2
Short access day 1 total inactive lever presses0.10.10.50.1-0.1-0.50.1-0.1-0.00.1-0.60.6-0.4-0.5-0.2-0.20.30.2-0.40.4-0.50.20.0-0.3-0.7
Short access day 10 total inactive lever presses2.02.25.9-1.51.52.2-1.41.41.3-1.40.6-0.70.8-0.71.7-0.80.50.62.1-2.12.4-1.81.22.21.4
Short access day 1 total infusions9.09.612.13.3-3.4-3.13.3-3.3-3.33.31.4-1.2-3.22.9-3.43.1-2.9-2.9-3.23.2-2.93.4-3.3-3.2-3.5
Short access day 10 total infusions1.81.93.01.5-1.5-1.61.4-1.4-1.41.50.4-0.3-0.71.2-1.61.4-1.0-1.2-1.71.6-1.61.6-1.4-1.7-1.5
Short access total infusions5.25.77.42.6-2.6-2.52.5-2.5-2.62.61.0-0.8-2.12.2-2.72.4-2.1-2.2-2.62.6-2.52.7-2.5-2.6-2.7
Short access day 1 locomotion1.81.94.71.3-1.4-1.01.3-1.4-1.41.41.1-1.0-1.41.6-1.41.8-1.4-1.4-1.11.1-1.11.3-1.4-1.1-2.2
Short access day 10 total locomotion0.91.01.6-1.11.11.0-1.11.11.1-1.1-0.50.41.2-0.81.1-0.81.10.90.9-1.00.8-1.11.10.90.7
Short access total locomotion0.30.31.10.4-0.4-0.30.4-0.4-0.40.40.4-0.4-0.20.7-0.50.8-0.3-0.4-0.50.5-0.60.5-0.5-0.4-1.1
Compulsive drug intake0.20.20.3-0.50.50.3-0.50.50.5-0.5-0.20.2-0.0-0.50.4-0.40.40.60.3-0.30.3-0.40.40.3-0.0
One hour access (0.3 mA shock)3.03.57.52.1-2.0-2.52.0-1.9-1.82.0-0.70.8-0.51.0-2.11.1-0.9-1.1-2.72.6-2.72.2-1.6-2.7-1.5
One hour access (shock baseline)1.61.84.11.5-1.5-1.71.5-1.4-1.31.4-0.40.50.00.7-1.50.9-0.6-0.9-2.01.8-2.01.6-1.2-2.0-0.8
Number of responses in last shaping day0.10.10.2-0.20.20.4-0.20.10.1-0.20.5-0.50.00.10.10.3-0.20.10.3-0.50.4-0.20.00.3-0.2
Context. condit. distance diff. score0.00.00.10.1-0.10.10.1-0.1-0.10.10.3-0.3-0.10.3-0.00.3-0.1-0.30.0-0.1-0.00.0-0.10.1-0.2
Locomotion velocity, session 111.412.322.1-3.53.61.9-3.73.83.9-3.7-3.63.53.8-4.33.3-4.44.24.72.2-2.31.4-3.13.92.33.7
Locomotion distance, session 10.20.30.9-0.50.50.1-0.50.50.5-0.5-0.60.60.7-0.10.4-0.11.00.70.2-0.3-0.5-0.40.60.20.6
Locomotion velocity, session 26.07.010.1-2.82.82.0-2.82.92.9-2.9-2.22.02.9-2.82.7-3.03.13.22.1-2.21.5-2.73.02.22.9
Locomotion distance, session 20.30.51.4-0.50.50.1-0.50.60.6-0.5-1.21.21.1-0.60.5-0.71.10.90.2-0.2-0.4-0.40.80.20.6
Locomotion velocity, session 32.63.04.7-1.81.91.1-1.91.92.0-1.9-1.71.62.0-1.81.8-1.82.22.21.3-1.40.5-1.72.01.31.6
Locomotion distance, session 36.97.511.9-2.82.92.0-2.93.03.0-2.9-2.22.12.8-3.52.8-3.43.03.22.2-2.21.7-2.73.02.22.7
Stereotopy head waving bouts, day 36.57.814.52.6-2.8-1.62.7-2.8-3.02.83.1-2.9-3.23.8-2.73.8-3.1-3.3-1.91.9-1.62.6-3.1-1.9-2.8
Stereotopy head waving duration, day 30.81.02.0-1.01.10.6-1.11.11.1-1.1-1.11.01.2-1.01.0-1.01.41.30.7-0.70.1-0.91.20.71.0
Locomotion velocity, session 73.53.86.7-1.92.01.1-2.02.12.1-2.0-2.12.02.2-2.61.8-2.62.62.31.4-1.40.5-1.72.21.41.8
Locomotion distance, session 72.53.16.7-1.51.60.9-1.51.61.8-1.6-2.32.32.2-2.61.7-2.61.91.81.2-1.11.1-1.62.01.11.6
Stereotopy head waving bouts, day 70.40.40.7-0.80.70.7-0.80.80.7-0.80.3-0.30.2-0.30.6-0.40.60.70.8-0.80.4-0.70.50.80.6
Stereotopy head waving duration, day 73.44.25.9-2.42.31.9-2.42.42.3-2.4-0.80.71.7-1.92.2-1.92.22.42.1-2.11.3-2.12.22.12.1
Locomotion velocity, session 85.86.910.2-2.52.71.6-2.62.72.9-2.7-2.92.83.2-3.02.6-3.13.13.12.0-1.91.1-2.53.01.92.4
Locomotion distance, session 80.20.30.70.5-0.5-0.30.6-0.6-0.60.60.4-0.4-0.40.8-0.50.8-0.4-0.7-0.40.3-0.50.4-0.5-0.3-0.6
Degree of sensitization distance2.82.83.71.9-1.9-1.61.9-1.9-1.91.90.7-0.6-1.51.7-1.81.6-1.7-1.9-1.61.6-1.31.8-1.8-1.6-1.9
Degree of sensitization stereotypy2.93.14.3-2.02.01.6-2.12.02.0-2.0-0.70.61.4-1.71.9-1.81.82.01.8-1.81.3-1.91.91.81.8
Condit. Reinf. active minus inactive responses2.12.44.21.7-1.6-1.71.6-1.6-1.51.60.2-0.1-1.01.8-1.71.8-1.0-1.4-1.71.7-2.11.6-1.5-1.8-1.8
Condit. Reinf. active-inactive response ratio1.21.33.00.9-1.0-0.41.0-1.0-1.11.01.6-1.5-1.31.7-1.01.7-1.1-1.5-0.60.5-0.80.9-1.2-0.7-1.5
Condit. Reinf. active responses2.53.14.81.9-1.9-2.01.9-1.9-1.81.90.10.1-1.01.9-1.91.9-1.2-1.5-2.01.9-2.21.9-1.7-2.1-1.8
Condit. Reinf. inactive responses0.60.71.60.8-0.7-1.20.7-0.6-0.50.7-1.21.30.20.3-0.80.30.00.1-1.21.1-1.20.8-0.3-1.2-0.3
Incentive salience index mean0.50.61.30.9-0.8-1.00.8-0.8-0.70.8-0.40.5-0.10.8-0.80.7-0.3-0.5-1.00.9-1.10.8-0.6-1.1-0.8
Condit. Reinf. lever presses0.91.23.0-0.80.90.3-0.91.01.1-0.9-1.71.71.5-1.60.9-1.61.21.40.4-0.40.6-0.81.20.41.1
Time in familiar zone, hab. session 10.10.00.20.2-0.20.10.2-0.2-0.20.20.3-0.3-0.10.4-0.10.3-0.2-0.50.0-0.0-0.10.1-0.20.0-0.4
Time in novel zone, hab. session 10.00.00.10.1-0.1-0.30.1-0.1-0.10.1-0.20.20.0-0.1-0.2-0.1-0.10.2-0.30.3-0.20.2-0.1-0.30.1
Total zone transitions, hab. session 15.57.812.3-2.83.02.1-2.93.03.1-2.9-2.72.53.5-2.72.9-2.63.43.12.5-2.51.4-2.93.32.42.6
Total locomotion distance, hab. session 121.230.453.35.5-5.6-3.35.7-5.8-6.05.75.5-5.3-5.97.2-5.37.3-6.5-6.7-3.83.9-2.65.1-6.2-3.9-5.6
Locomotion velocity, hab. session 122.232.055.55.6-5.8-3.55.8-6.0-6.25.95.5-5.3-6.17.3-5.57.4-6.5-6.8-4.14.1-2.95.3-6.3-4.1-5.7
Time in familiar zone, hab. session 20.10.10.6-0.10.00.50.0-0.0-0.10.00.7-0.7-0.30.20.10.1-0.3-0.40.4-0.40.7-0.2-0.10.4-0.1
Time in novel zone, hab. session 20.30.31.70.3-0.3-0.90.1-0.1-0.10.2-0.80.90.0-0.2-0.5-0.20.40.5-0.80.8-1.30.6-0.1-0.80.0
Total zone transitions, hab. session 22.02.64.7-1.71.81.1-1.81.91.8-1.8-1.41.41.8-1.61.6-1.62.22.11.3-1.30.4-1.61.81.31.6
Total locomotion distance, hab. session 227.436.364.25.9-6.1-3.76.1-6.3-6.66.26.1-5.8-6.58.0-5.98.0-6.8-7.1-4.44.3-3.25.6-6.7-4.3-6.0
Locomotion velocity, hab. session 225.134.061.75.7-5.9-3.66.0-6.1-6.36.05.8-5.6-6.27.8-5.77.9-6.6-6.9-4.24.2-3.15.4-6.5-4.2-5.9
Novel to familiar place preference ratio1.21.21.61.2-1.2-1.11.2-1.2-1.21.20.6-0.6-1.31.1-1.31.1-1.2-1.1-1.11.1-0.81.2-1.2-1.2-1.1
Novelty place preference0.90.91.31.0-1.1-1.11.0-1.0-1.01.00.2-0.2-1.00.9-1.10.8-0.9-0.8-1.11.1-0.91.1-1.0-1.2-0.9
Time in novel zone, NPP test0.80.81.41.0-1.0-1.20.9-0.9-0.91.00.00.1-0.80.7-1.10.6-0.7-0.6-1.11.2-1.11.1-0.9-1.2-0.8
Total zone transitions, NPP test0.81.22.6-0.90.90.2-1.01.01.1-1.0-1.61.61.5-1.40.8-1.41.61.60.3-0.4-0.3-0.71.20.31.1
Total locomotion distance, NPP test32.444.970.56.8-7.0-4.67.1-7.2-7.47.16.0-5.7-7.08.3-6.88.4-7.5-7.8-5.35.3-4.06.5-7.5-5.3-6.7
Locomotion velocity, NPP test30.944.270.56.8-6.9-4.57.0-7.1-7.37.16.0-5.7-6.98.3-6.78.4-7.5-7.8-5.25.2-3.86.4-7.4-5.2-6.7
Pavlov. Cond. lever latency1.51.83.01.4-1.4-1.01.4-1.4-1.51.41.1-1.1-1.31.7-1.41.7-1.4-1.5-1.21.1-1.01.3-1.5-1.2-1.4
Pavlov. Cond. magazine entry latency0.20.30.60.5-0.5-0.80.5-0.5-0.40.5-0.30.4-0.20.1-0.60.0-0.1-0.2-0.70.7-0.80.6-0.4-0.7-0.2
Pavlov. Cond. change in total contacts0.20.20.9-0.30.30.6-0.20.20.2-0.20.5-0.50.00.10.4-0.0-0.1-0.20.6-0.60.9-0.40.10.60.2
Pavlov. Cond. index score0.40.51.2-0.60.70.2-0.70.70.7-0.7-0.90.90.8-1.00.6-1.10.90.80.4-0.40.2-0.60.80.40.8
Pavlov. Cond. latency score0.40.51.2-0.60.70.3-0.70.70.7-0.7-0.80.80.8-1.10.6-1.10.90.80.4-0.40.2-0.60.80.40.7
Pavlov. Cond. lever contacts0.91.11.9-1.11.10.8-1.11.11.1-1.1-0.70.70.9-1.31.0-1.41.01.00.9-0.90.9-1.01.10.91.1
Pavlov. Cond. magazine entry number0.20.21.0-0.0-0.00.50.0-0.1-0.20.11.0-1.0-0.50.60.10.8-0.6-0.40.3-0.40.6-0.1-0.30.3-0.4
Pavlov. Cond. intertrial magazine entries0.30.31.1-0.60.60.9-0.60.50.5-0.60.4-0.50.10.10.70.10.20.20.8-0.91.0-0.70.40.70.2
Pavlov. Cond. lever-magazine prob. diff.0.60.71.3-0.80.80.6-0.80.90.9-0.9-0.70.70.8-1.10.8-1.10.90.80.7-0.70.6-0.80.90.70.9
Pavlov. Cond. response bias0.10.10.3-0.20.20.0-0.20.20.2-0.2-0.50.50.3-0.50.2-0.50.30.30.1-0.00.2-0.20.30.10.5
Bone: apparent density0.40.62.1-0.60.61.3-0.50.40.4-0.50.8-0.90.30.30.80.3-0.0-0.21.2-1.21.5-0.90.41.20.2
Bone surface0.20.41.3-0.50.51.1-0.40.40.3-0.40.9-1.00.10.20.60.1-0.0-0.31.0-1.01.1-0.70.21.00.3
Bone volume0.20.41.2-0.50.41.1-0.40.30.3-0.40.9-0.90.10.30.60.3-0.0-0.31.0-0.91.0-0.70.21.00.1
Bone: connectivity density0.50.73.2-0.50.51.5-0.30.30.3-0.41.2-1.30.10.40.80.3-0.3-0.61.3-1.21.8-0.90.21.30.2
Bone: cortical apparent density0.60.82.50.9-0.8-1.30.8-0.7-0.70.8-0.70.8-0.30.1-1.00.2-0.1-0.1-1.21.3-1.61.1-0.6-1.3-0.6
Bone: cortical area0.20.30.9-0.40.40.9-0.30.20.2-0.30.7-0.70.20.30.50.3-0.0-0.40.8-0.80.9-0.60.20.80.1
Bone: cortical porosity0.50.61.2-0.90.90.4-1.01.00.9-0.9-0.50.50.5-0.90.6-0.91.01.10.4-0.50.1-0.60.80.50.9
Bone: cortical porosity0.20.20.5-0.60.60.3-0.70.70.5-0.6-0.20.20.2-0.50.4-0.50.60.70.3-0.3-0.1-0.40.50.30.4
Bone: cortical thickness0.00.00.10.00.00.30.1-0.0-0.00.00.0-0.10.20.10.10.20.0-0.30.2-0.20.4-0.10.10.2-0.1
Bone: cortical thickness0.20.20.6-0.30.40.1-0.30.40.4-0.3-0.80.80.7-0.50.3-0.40.80.50.2-0.3-0.3-0.30.50.10.1
Bone: cortical tissue density0.60.82.60.9-0.9-1.40.8-0.8-0.70.8-0.60.7-0.30.1-1.00.2-0.1-0.1-1.31.3-1.61.1-0.6-1.3-0.6
Bone: elastic displacement0.20.20.60.5-0.4-0.70.5-0.4-0.30.4-0.70.80.30.1-0.40.0-0.3-0.1-0.60.6-0.30.4-0.2-0.6-0.1
Bone: elastic work0.10.10.20.3-0.2-0.30.3-0.3-0.20.3-0.40.40.30.3-0.20.3-0.2-0.1-0.30.3-0.10.2-0.1-0.4-0.1
Bone: endosteal estimation0.40.92.0-1.11.01.4-1.00.90.8-1.01.0-1.00.2-0.01.0-0.10.40.31.3-1.31.0-1.10.61.40.6
Bone: endosteal perimeter0.20.31.7-0.30.20.8-0.20.10.0-0.21.3-1.3-0.40.50.20.5-0.3-0.60.6-0.60.5-0.3-0.10.70.1
Bone: final force0.61.02.7-1.01.01.7-0.90.90.8-0.90.5-0.60.70.11.20.10.70.01.6-1.61.2-1.30.81.50.5
Bone: final moment0.50.82.0-0.80.91.4-0.70.70.7-0.80.4-0.40.70.21.10.10.5-0.01.4-1.41.1-1.10.71.30.5
Bone: marrow area0.30.71.7-1.00.91.3-0.90.80.7-0.91.0-1.10.10.00.9-0.00.30.21.2-1.21.0-1.00.51.30.5
Bone: maximum diameter0.10.20.5-0.50.50.7-0.40.40.4-0.40.2-0.20.50.20.50.10.4-0.00.7-0.70.2-0.60.40.70.2
Bone: maximum force0.61.02.3-1.01.01.5-0.90.90.9-1.00.2-0.30.9-0.21.2-0.20.70.31.5-1.51.2-1.30.91.40.7
Bone: maximum moment0.40.71.7-0.80.91.3-0.70.70.8-0.80.1-0.20.9-0.11.0-0.20.50.21.2-1.21.2-1.10.81.20.7
Bone: minimum diameter0.81.57.8-0.20.01.4-0.0-0.1-0.40.02.7-2.8-1.21.20.21.2-1.2-1.51.0-1.11.7-0.4-0.61.00.0
Bone: periosteal estimation0.51.02.7-1.11.01.7-0.90.90.8-0.91.1-1.20.20.11.1-0.10.3-0.01.5-1.51.4-1.20.61.50.5
Bone: periosteal perimeter0.10.10.4-0.30.30.6-0.20.20.2-0.20.5-0.60.00.10.30.00.0-0.30.5-0.50.5-0.40.10.50.2
Bone: post-yield work1.01.31.8-1.21.31.2-1.21.21.2-1.2-0.40.41.2-1.01.3-1.10.91.11.2-1.21.3-1.31.21.21.3
Bone: stiffness0.30.41.5-0.30.31.1-0.20.10.1-0.21.2-1.2-0.20.60.50.6-0.2-0.71.0-1.00.9-0.50.00.9-0.2
Bone: tissue strength0.30.21.2-0.20.30.8-0.10.10.2-0.20.4-0.50.40.50.50.5-0.2-0.20.7-0.71.1-0.50.20.80.3
Bone: trabecular number0.30.52.5-0.30.31.2-0.20.10.2-0.20.9-1.00.10.40.60.4-0.4-0.61.1-1.01.6-0.70.21.00.0
Bone: trabecular spacing1.11.43.0-1.21.20.5-1.31.31.3-1.3-1.31.21.2-1.61.1-1.51.51.70.6-0.70.3-1.01.30.71.2
Bone: trabecular thickness0.50.61.50.8-0.8-0.80.8-0.8-0.80.80.2-0.2-0.61.0-0.91.0-0.4-0.8-0.70.8-1.20.9-0.8-0.8-1.0
Bone: trabecular tissue density0.20.32.30.2-0.2-0.80.1-0.0-0.10.1-0.70.70.1-0.1-0.4-0.00.50.5-0.70.6-1.50.5-0.1-0.6-0.3
Breakpoint value in progressive ratio session1.01.12.00.9-1.1-0.51.0-1.0-1.21.01.4-1.4-1.41.3-1.11.2-1.1-1.2-0.90.7-0.41.0-1.3-0.7-0.5
Distance traveled before self-admin0.70.72.90.4-0.60.40.5-0.6-0.80.61.7-1.7-0.71.1-0.51.4-1.2-1.20.1-0.10.20.4-0.90.2-0.6
Distance traveled after self-admin0.91.05.00.3-0.50.60.4-0.5-0.70.52.2-2.2-1.01.3-0.41.3-1.4-1.30.4-0.40.70.3-0.90.5-0.7
Delta time in closed arm before/after self-admin4.94.86.2-2.42.42.0-2.42.42.4-2.4-1.61.41.9-2.32.4-2.32.32.32.2-2.11.7-2.32.52.21.9
Delta time in open arm before/after self-admin0.00.00.3-0.00.00.0-0.0-0.0-0.0-0.00.2-0.20.2-0.10.0-0.1-0.1-0.1-0.0-0.00.1-0.0-0.00.10.5
Diff in mean of infusions in LGA sessions1.41.53.3-1.51.41.7-1.41.31.2-1.40.6-0.70.6-0.71.4-0.70.80.81.4-1.81.7-1.41.11.31.4
Extinction: sum of active levers before priming1.21.21.81.2-1.3-1.11.2-1.2-1.31.20.6-0.5-0.71.0-1.30.9-1.0-1.0-1.31.2-1.01.3-1.2-1.2-0.5
Active lever presses in extinction session 61.91.82.41.5-1.5-1.21.5-1.5-1.51.50.8-0.7-1.11.5-1.51.5-1.3-1.3-1.51.4-1.01.5-1.5-1.4-1.0
Delta distance traveled before/after self-admin0.10.10.50.2-0.2-0.10.2-0.2-0.30.20.7-0.7-0.70.3-0.2-0.0-0.4-0.4-0.2-0.00.10.2-0.4-0.20.0
Delta ambulatory time before/after self-admin0.10.20.50.3-0.4-0.30.4-0.4-0.40.40.5-0.5-0.70.4-0.40.0-0.5-0.4-0.40.2-0.10.4-0.5-0.4-0.1
Time in closed arm before self-admin1.72.02.51.5-1.5-1.51.5-1.5-1.51.50.7-0.6-1.41.5-1.61.4-1.4-1.2-1.51.6-1.41.6-1.5-1.4-1.0
Time in closed arm after self-admin0.10.10.3-0.20.2-0.1-0.20.30.3-0.2-0.50.5-0.0-0.30.2-0.20.30.50.20.0-0.2-0.20.30.20.1
Time in open arm before self-admin0.40.40.9-0.60.60.7-0.70.70.6-0.7-0.50.40.9-0.80.6-0.60.70.60.5-0.50.4-0.60.70.50.5
Time in open arm after self-admin0.70.81.9-0.90.90.8-0.90.90.9-0.9-0.50.51.4-1.00.9-1.00.90.80.7-0.80.7-0.90.90.71.2
Sum of active levers in priming session hrs 5-68.28.110.93.2-3.2-3.03.1-3.1-3.13.21.2-1.0-2.72.7-3.22.5-2.6-2.6-3.33.1-2.73.2-3.1-3.2-2.2
Time to tail flick, vehicle, before self-admin2.93.04.8-1.61.71.0-1.61.71.9-1.7-2.22.12.0-2.01.8-1.82.02.01.3-1.20.9-1.72.11.21.4
Time to tail flick, vehicle, after self-admin3.53.76.9-2.02.01.3-2.12.12.1-2.1-1.71.61.9-2.31.9-2.62.22.31.5-1.50.8-1.82.21.61.6
Time to tail flick, test, before self-admin2.82.73.8-1.81.81.8-1.81.81.8-1.8-0.50.41.3-1.41.9-1.61.31.31.9-1.91.8-1.91.72.01.9
Time to tail flick, test, after self-admin4.04.16.1-2.12.11.3-2.12.22.2-2.1-2.01.91.7-2.52.0-2.32.42.41.5-1.61.1-1.92.31.62.3
Delta time to tail flick, vehicle, before/after SA0.70.71.7-0.90.90.7-1.00.90.9-0.9-0.40.41.0-0.90.9-1.30.90.90.7-0.70.4-0.80.90.80.7
Delta time to tail flick, test, before/after SA0.10.10.20.2-0.1-0.30.1-0.1-0.10.1-0.40.4-0.3-0.0-0.10.10.20.2-0.40.3-0.30.10.0-0.3-0.4
Ambulatory time before self-admin0.70.72.00.6-0.70.10.7-0.8-0.80.71.3-1.3-0.51.2-0.61.4-1.1-1.2-0.10.2-0.00.6-0.9-0.2-0.8
Ambulatory time after self-admin0.91.04.60.4-0.50.60.5-0.6-0.70.52.1-2.1-1.21.3-0.31.3-1.5-1.40.5-0.40.70.2-0.90.5-0.8
Total heroin consumption0.40.51.40.8-0.8-0.50.8-0.8-0.80.80.5-0.5-1.20.8-0.80.7-0.8-0.8-0.80.6-0.30.7-0.8-0.6-0.3
Area under the delay curve1.81.92.7-1.61.61.5-1.61.61.6-1.6-0.50.40.9-1.11.5-1.21.51.51.4-1.51.3-1.51.51.31.3
Delay disc. indifference point, 0s delay0.91.03.40.4-0.60.30.6-0.6-0.80.61.8-1.8-1.31.7-0.51.6-1.2-1.20.0-0.00.50.4-0.9-0.0-1.3
Delay disc. indifference point, 16s delay1.61.62.8-1.41.40.9-1.51.51.4-1.4-1.00.91.0-1.51.2-1.51.71.70.9-1.00.4-1.11.40.81.3
Delay disc. indifference point, 2s delay1.21.32.2-1.31.31.5-1.31.21.2-1.3-0.1-0.00.9-0.71.3-0.70.90.91.4-1.51.4-1.41.21.31.1
Delay disc. indifference point, 24s delay1.51.52.3-1.31.30.9-1.41.41.4-1.3-1.00.91.0-1.41.2-1.51.51.50.9-1.10.6-1.11.30.81.5
Delay disc. indifference point, 4s delay1.31.33.6-1.21.11.7-1.11.00.8-1.01.4-1.5-0.40.31.20.40.10.11.7-1.71.9-1.30.61.5-0.4
Delay disc. indifference point, 8s delay1.51.62.1-1.41.41.1-1.41.41.4-1.4-0.90.91.3-1.31.3-1.41.41.41.0-1.10.9-1.31.41.01.4
Delay discount exponential model param1.61.72.41.5-1.5-1.41.5-1.5-1.51.50.5-0.4-0.91.0-1.51.2-1.4-1.4-1.31.4-1.21.5-1.4-1.1-1.3
Delay discount hyperbolic model param1.61.72.51.6-1.5-1.61.5-1.5-1.41.50.2-0.1-0.80.9-1.51.0-1.2-1.2-1.41.6-1.41.5-1.4-1.3-1.1
Fecal boli incidents, locomotor time 11.01.11.7-1.21.11.3-1.21.11.0-1.10.4-0.50.2-1.11.1-1.20.80.81.3-1.31.2-1.10.81.10.9
Change in fecal boli incidents, locomotor task0.40.31.30.6-0.6-0.70.6-0.6-0.60.60.0-0.0-0.40.6-0.60.9-0.6-0.6-0.50.6-0.40.6-0.5-0.3-1.1
Time >=10cm from walls, locomotor time 10.60.63.3-0.1-0.10.70.0-0.1-0.30.11.8-1.8-0.50.80.10.8-0.7-0.90.7-0.70.8-0.1-0.40.7-0.4
Bouts of movement, locomotor time 11.31.52.4-1.31.30.9-1.31.31.3-1.3-0.80.81.0-1.41.3-1.51.31.31.0-1.00.9-1.21.31.01.5
Total resting periods, locomotor time 11.11.22.2-1.11.10.7-1.11.21.2-1.2-1.00.91.1-1.31.1-1.51.31.30.8-0.80.7-1.11.20.81.5
Rest time, locomotor task time 10.50.61.4-0.70.70.6-0.70.70.7-0.7-0.40.41.0-0.90.8-1.10.70.60.7-0.60.7-0.70.70.61.2
Distance moved, locomotor task time 10.20.31.40.4-0.4-0.20.4-0.4-0.40.40.2-0.2-0.51.0-0.41.2-0.4-0.4-0.30.4-0.40.3-0.3-0.1-0.9
Vertical activity count, locomotor time 11.21.23.70.8-0.9-0.10.9-0.9-1.00.91.8-1.8-1.21.7-0.81.9-1.5-1.4-0.40.40.00.7-1.2-0.3-1.2
Time >=10cm from walls, locomotor time 20.80.84.1-0.30.11.1-0.10.0-0.2-0.12.0-2.0-0.50.90.21.1-0.8-0.81.2-1.01.1-0.3-0.31.1-0.3
Bouts of movement, locomotor time 20.80.91.7-1.11.00.7-1.11.11.1-1.1-0.40.40.4-1.30.9-1.21.11.00.8-0.90.6-0.91.00.41.1
Total resting periods, locomotor time 20.50.51.0-0.80.80.4-0.90.90.8-0.8-0.30.30.3-1.00.7-1.00.90.80.5-0.60.4-0.60.70.20.8
Rest time, locomotor task time 20.60.70.90.9-0.9-0.80.9-0.9-0.90.90.6-0.6-0.80.9-0.90.8-0.9-0.9-0.80.9-0.60.9-0.9-0.8-0.8
Distance moved, locomotor task time 20.30.42.00.4-0.40.30.5-0.5-0.50.40.9-0.9-0.61.2-0.21.4-0.8-0.80.2-0.20.40.2-0.50.1-0.4
Vertical activity count, locomotor time 23.43.710.01.5-1.6-0.21.6-1.8-1.91.73.2-3.1-2.22.4-1.52.7-2.7-2.6-0.70.60.31.3-2.2-0.6-1.4
Weight adjusted by age0.20.30.80.3-0.40.10.4-0.4-0.50.40.9-0.9-0.60.6-0.30.6-0.8-0.80.1-0.00.20.3-0.5-0.10.1
Seeking ratio, delayed vs. immediate footshock0.30.40.6-0.60.60.3-0.60.70.7-0.7-0.60.50.8-0.60.6-0.30.70.70.6-0.70.2-0.60.70.40.5
Locomotion in novel chamber1.62.02.6-1.61.61.3-1.61.61.6-1.6-1.00.91.3-1.31.5-1.31.61.61.3-1.30.9-1.51.61.41.3
Locomotion in novel chamber post-restriction1.01.13.40.9-0.7-1.60.7-0.6-0.50.7-1.71.90.7-0.4-0.9-0.70.20.3-1.61.5-1.81.0-0.3-1.4-0.0
Progressive ratio0.80.92.31.0-1.0-1.30.9-0.9-0.90.9-0.10.2-0.90.4-1.20.3-0.5-0.4-1.41.3-1.41.2-0.9-1.5-0.6
Food seeking constrained by brief footshock3.03.76.41.9-2.0-1.61.9-1.9-2.11.91.8-1.7-2.22.0-2.01.7-2.0-1.9-1.91.8-1.32.0-2.2-1.7-2.5
Seeking ratio, punishment vs. effort0.60.82.90.5-0.60.10.6-0.7-0.80.61.7-1.7-1.01.2-0.51.1-1.2-1.20.0-0.00.40.4-0.90.1-1.2
Run reversals in cocaine runway, females0.40.41.00.7-0.7-0.80.6-0.6-0.70.70.00.0-0.20.3-0.80.3-0.3-0.3-0.70.8-1.00.8-0.6-0.8-0.4
Run reversals in cocaine runway, males1.31.26.20.10.0-1.1-0.00.20.3-0.1-2.42.51.6-1.2-0.2-1.21.21.1-1.00.9-1.50.30.6-1.00.7
Latency to leave start box in cocaine runway4.24.517.71.0-1.30.61.3-1.5-1.81.44.2-4.2-3.12.8-1.13.1-2.8-2.70.10.01.10.9-2.10.2-1.4
Latency to leave start box in cocaine runway, F1.92.110.70.0-0.21.30.2-0.4-0.70.33.2-3.3-2.11.7-0.12.0-1.6-1.51.0-0.81.6-0.1-0.91.1-0.5
Latency to leave start box in cocaine runway, M4.64.47.91.9-2.0-0.92.0-2.1-2.22.02.7-2.7-2.52.7-1.82.8-2.7-2.7-1.21.1-0.31.7-2.4-1.2-2.0
Cd content in liver7.07.79.42.9-3.0-2.42.9-3.0-3.03.01.9-1.7-2.83.0-3.03.0-2.8-2.8-2.72.7-2.43.0-3.1-2.6-2.7
Co content in liver0.00.00.30.1-0.1-0.1-0.0-0.0-0.20.10.3-0.3-0.50.0-0.3-0.00.00.0-0.10.2-0.40.3-0.2-0.1-0.0
Cu content in liver1.01.22.6-1.31.21.6-1.21.21.0-1.20.8-0.90.1-0.61.2-0.80.60.61.5-1.41.5-1.20.81.60.8
Fe content in liver0.30.40.80.6-0.6-0.30.6-0.6-0.70.60.8-0.8-0.70.9-0.60.7-0.7-0.7-0.40.4-0.30.6-0.7-0.3-0.2
K content in liver0.20.20.90.1-0.10.50.2-0.2-0.30.20.9-0.9-0.30.70.00.8-0.4-0.80.4-0.50.7-0.1-0.20.4-0.2
Mg content in liver0.80.81.7-1.01.01.3-1.00.90.9-1.00.3-0.40.5-0.41.1-0.30.80.41.2-1.31.2-1.10.81.30.7
Mn content in liver0.30.31.0-0.30.40.1-0.40.40.5-0.4-1.01.00.9-0.50.5-0.41.00.40.2-0.3-0.4-0.40.70.20.1
Na content in liver8.38.914.6-3.33.33.7-3.23.13.1-3.2-0.2-0.02.4-2.03.4-2.02.42.23.8-3.73.5-3.53.03.82.8
Rb content in liver0.30.31.4-0.20.20.9-0.20.10.0-0.21.1-1.2-0.40.60.30.6-0.1-0.70.7-0.80.7-0.4-0.00.7-0.1
Se content in liver0.40.52.2-0.20.11.0-0.0-0.0-0.0-0.11.1-1.2-0.20.70.30.7-0.7-0.70.9-0.91.5-0.4-0.10.80.1
Sr content in liver1.51.42.8-1.21.30.8-1.31.41.4-1.3-1.21.21.3-1.11.2-1.11.71.31.1-1.0-0.2-1.11.41.10.5
Zn content in liver0.20.20.70.5-0.50.10.5-0.6-0.50.50.6-0.6-0.40.7-0.30.7-0.8-0.7-0.0-0.10.60.2-0.5-0.0-0.2