Hub : Genes

Nt5c3b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016475 0.03 0.01 7.9e-04 0.01 0.02 0.02 0.01 2.3e-02 9.6e-04 2.5e-03 7.0e-03
2 BLA gene expression ENSRNOG00000016475 0.06 0.04 1.6e-03 0.01 0.01 -0 0 1.1e-01 6.9e-02 5.8e-01 2.2e-01
3 Brain gene expression ENSRNOG00000016475 0.05 0.02 2.9e-06 0.09 0.05 0.06 0.07 2.2e-08 1.1e-05 2.2e-06 8.3e-07
4 IL gene expression ENSRNOG00000016475 0.16 0.1 3.6e-03 0.05 0.09 0.03 0.04 2.5e-02 3.8e-03 8.3e-02 4.6e-02
5 Liver gene expression ENSRNOG00000016475 0.02 0.01 7.7e-03 0.01 0.02 0 0.01 1.4e-02 4.9e-03 1.5e-01 2.5e-02
6 Liver intron excision ratio chr10:85370652:85374547 0.07 0.05 2.1e-03 -0 0.01 0 0 3.9e-01 1.4e-02 2.7e-01 3.1e-01
7 OFC gene expression ENSRNOG00000016475 0.14 0.08 3.3e-03 0.12 0.06 0.05 0.11 7.3e-04 1.6e-02 2.3e-02 1.7e-03
8 PL gene expression ENSRNOG00000016475 0.03 0.02 7.6e-03 0.01 0.02 0 0.01 9.5e-02 1.3e-02 3.4e-01 1.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.20.61.9-0.6-0.8-1.4-0.40.10.5-1.2-0.6
BMI without tail1.73.66.3-1.8-1.9-2.4-1.21.2-1.6-2.5-2.0
Body weight0.20.83.5-0.6-0.7-0.3-1.20.91.9-0.1-0.3
Epididymis fat weight0.10.20.5-0.5-0.7-0.4-0.20.40.7-0.1-0.5
Glucose0.20.30.9-0.2-0.2-0.90.1-0.0-0.5-1.0-0.4
Heart weight0.60.81.4-1.0-1.1-0.9-1.20.60.9-0.7-0.8
Left kidney weight0.51.53.41.11.00.70.2-1.81.61.01.4
Right kidney weight0.61.73.21.31.20.70.9-1.81.71.01.4
Tail length1.03.03.6-1.9-1.9-1.4-1.91.7-1.6-1.6-1.8
Length with tail0.20.82.9-0.7-0.70.4-1.71.11.10.3-0.3
Length without tail1.43.09.21.21.02.10.1-0.43.02.31.5
Liver weight, left0.10.10.3-0.2-0.2-0.0-0.50.3-0.6-0.4-0.2
Liver weight, right0.71.23.01.21.30.61.1-1.70.10.71.2
Parametrial fat weight0.00.10.20.10.00.30.40.20.20.4-0.0
Retroperitoneal fat weight0.00.10.80.10.0-0.1-0.3-0.10.90.40.1
Intraocular pressure4.86.78.2-2.9-2.7-2.6-2.62.4-2.4-2.5-2.7
Extensor digitorum longus weight5.120.526.9-4.8-4.9-4.4-5.24.8-2.7-4.3-4.6
Soleus weight0.10.30.6-0.4-0.5-0.7-0.20.80.0-0.6-0.6
Tibialis anterior weight1.03.44.3-1.9-2.0-1.9-2.11.8-1.3-1.8-1.8
Tibia length0.41.06.00.40.20.8-0.2-0.32.50.70.7
Number of licking bursts1.11.42.61.21.00.81.6-1.41.20.81.1
Food consumed during 24 hour testing period0.10.10.60.20.1-0.00.1-0.60.8-0.00.4
Times rat made contact with spout0.10.10.5-0.0-0.2-0.10.40.10.7-0.1-0.1
Mean time between licks in bursts0.20.21.20.1-0.2-0.20.6-0.41.1-0.40.1
Mean num. licks in bursts1.51.92.8-1.4-1.4-1.2-1.51.7-1.0-1.1-1.5
Std. dev. time between licks in bursts0.10.20.5-0.3-0.3-0.50.20.1-0.7-0.6-0.4
Water consumed over 24 hours1.41.73.01.21.21.01.4-1.41.71.11.3
Indifference point 0 sec0.10.10.4-0.00.20.7-0.40.2-0.50.20.2
Indifference point AUC0.20.20.40.50.60.40.6-0.5-0.10.40.5
Indifference point function ln k0.30.40.70.40.40.9-0.4-0.10.80.80.6
Indifference point function log k0.30.40.70.40.40.9-0.4-0.10.80.80.6
Delay discounting total patch changes 0 sec0.10.10.4-0.10.20.6-0.40.2-0.40.20.1
Delay discounting total patch changes 12 sec0.91.22.21.11.31.21.5-0.8-0.41.00.9
Delay discounting total patch changes 18 sec0.10.10.7-0.10.20.10.20.0-0.8-0.2-0.1
Delay discounting total patch changes 24 sec0.10.20.50.30.30.60.3-0.3-0.70.10.3
Delay discounting total patch changes 6 sec0.20.31.6-0.5-0.2-0.0-0.40.4-1.3-0.3-0.4
Delay discounting time to switch 0 sec0.71.12.7-0.9-0.9-1.4-0.50.5-1.6-1.2-1.0
Delay discounting water rate 0 sec0.00.00.10.0-0.00.3-0.20.10.30.00.1
Delay discounting water rate 12 sec0.10.20.40.50.60.60.3-0.20.30.50.4
Delay discounting water rate 18 sec2.73.65.41.81.72.21.0-1.62.32.22.0
Delay discounting water rate 24 sec0.10.10.3-0.3-0.2-0.6-0.10.1-0.5-0.4-0.3
Delay discounting water rate 6 sec1.21.72.21.41.51.31.1-1.40.81.31.4
Locomotor activity0.50.71.70.91.10.41.3-1.0-0.20.30.8
Locomotor testing distance0.40.71.90.91.10.61.4-0.9-0.70.20.7
Locomotor testing rearing0.60.96.30.00.2-0.40.4-0.3-2.5-0.8-0.2
Light reinforcement 10.30.60.80.90.90.90.9-0.8-0.10.90.8
Light reinforcement 20.10.10.50.10.10.10.0-0.0-0.70.0-0.1
Reaction time number correct0.10.10.4-0.1-0.2-0.0-0.40.20.7-0.2-0.1
Reaction time mean minus median0.20.20.9-0.5-0.40.1-0.41.0-0.2-0.0-0.5
Reaction time mean minus median AUC0.10.10.5-0.20.00.4-0.20.7-0.50.2-0.2
Reaction time num false alarms0.50.72.20.90.90.41.5-1.10.50.30.7
Reaction time num false alarms AUC0.71.02.21.01.10.71.5-1.00.80.50.9
Reaction time trials correct on left0.10.10.4-0.1-0.2-0.0-0.40.20.7-0.2-0.1
Reaction time trials on left0.10.10.4-0.1-0.10.0-0.30.10.6-0.2-0.1
Reaction time mean1.11.52.71.21.41.61.3-1.0-0.11.51.2
Reaction time mean AUC0.60.81.40.71.01.20.9-0.6-0.71.00.8
Median of all reaction times2.12.84.21.61.92.01.8-1.50.11.91.7
Reaction time omissions1.31.82.81.41.71.41.5-1.20.11.51.4
Reaction time false alarm rate0.50.72.10.90.90.61.5-0.90.40.50.7
Reaction time premature initiation rate0.10.10.5-0.0-0.1-0.60.2-0.3-0.7-0.1-0.2
Reaction time premature initiations0.10.10.5-0.2-0.3-0.7-0.1-0.1-0.3-0.3-0.3
Std. dev. reaction times0.20.20.50.30.50.70.70.1-0.10.70.3
Reaction time trials completed0.10.10.4-0.1-0.10.0-0.30.10.6-0.2-0.1
Reaction time trials AUC0.10.10.50.0-0.00.1-0.20.00.7-0.20.0
Social response proportion1.61.83.3-1.3-1.3-1.8-1.20.4-1.1-1.8-1.2
Social responses0.10.20.5-0.2-0.2-0.6-0.1-0.3-0.6-0.7-0.2
Social time0.40.62.2-0.7-0.80.3-0.61.50.2-0.1-0.8
Conditioned locomotion0.10.10.50.30.2-0.00.5-0.7-0.20.00.3
Cocaine response after cond. corrected0.10.20.40.40.40.30.6-0.40.20.40.4
Cocaine response after cond. not corrected0.40.40.70.60.60.80.6-0.30.80.80.5
Cocaine response before conditioning0.30.41.10.20.20.9-0.10.11.00.90.3
Saline control response0.10.20.4-0.5-0.60.3-0.40.70.10.2-0.4
Condit. Reinf. active minus inactive responses0.40.40.80.60.90.90.7-0.3-0.40.70.6
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.10.3-0.00.4-0.50.1-0.1
Condit. Reinf. active responses0.60.81.51.01.21.01.1-0.4-0.50.90.8
Condit. Reinf. inactive responses0.91.11.81.31.31.01.3-0.70.21.11.0
Condit. Reinf. lever presses0.60.84.0-0.6-0.3-0.7-0.60.5-2.0-0.8-0.6
Condit. Reinf. lever reinforcers received0.40.61.20.81.10.80.9-0.4-0.80.70.7
Pavlov. Cond. lever latency0.10.10.7-0.3-0.5-0.0-0.20.20.90.2-0.2
Pavlov. Cond. magazine entry latency0.00.00.1-0.10.1-0.2-0.30.2-0.3-0.3-0.1
Pavlov. Cond. change in total contacts0.30.41.00.81.00.60.5-0.4-0.30.50.7
Pavlov. Cond. index score0.10.10.60.20.4-0.10.1-0.0-0.8-0.30.1
Pavlov. Cond. latency score0.10.10.50.10.3-0.2-0.00.1-0.7-0.40.0
Pavlov. Cond. lever contacts0.10.10.70.20.3-0.10.2-0.2-0.8-0.40.1
Pavlov. Cond. magazine entry number0.20.30.8-0.7-0.9-0.6-0.20.3-0.0-0.3-0.6
Pavlov. Cond. intertrial magazine entries0.30.41.6-0.1-0.20.6-0.4-0.31.30.90.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.30.5-0.00.0-0.0-0.6-0.20.2
Pavlov. Cond. response bias0.20.30.60.60.80.40.4-0.5-0.40.10.5
Conditioned reinforcement - actives0.90.91.9-0.9-0.9-0.7-0.50.9-1.4-1.1-1.0
Conditioned reinforcement - inactives1.71.93.51.21.11.71.4-0.61.91.81.1
Conditioned locomotion3.94.78.7-2.0-1.9-2.1-1.22.2-3.0-2.3-2.3
Intermittent access intake day 1-15 change3.73.65.62.01.71.82.4-1.62.02.01.7
Intermittent access intake escalation4.54.46.92.21.91.82.6-2.12.12.02.0
Intermittent access intake escalation 22.62.54.31.71.41.32.1-1.51.81.31.5
Intermitt. access day 1 inactive lever presses1.31.42.11.10.91.11.3-1.41.41.21.0
Intermitt. access day 15 inactive lever presses3.13.46.71.71.62.22.1-1.11.42.61.6
Intermitt. access escalation Index0.10.10.4-0.0-0.0-0.3-0.7-0.00.3-0.10.1
Intermittent access day 1 total infusions0.30.40.9-0.7-0.70.0-0.81.0-0.4-0.1-0.6
Intermittent access day 15 total infusions1.01.11.71.00.91.31.1-0.81.01.20.9
Intermittent access terminal intake (last 3 days)1.01.12.31.00.81.51.0-0.51.11.30.9
Intermittent access total infusions0.20.20.80.30.10.90.10.10.40.60.2
Intermittent access day 1 locomotion0.30.31.4-0.6-0.50.0-0.21.2-0.30.1-0.7
Intermittent access day 15 total locomotion0.60.61.50.70.70.91.20.10.80.90.5
Intermittent access total locomotion0.20.21.00.30.30.41.00.10.20.50.2
Intermittent access standard deviation1.11.23.01.10.90.91.7-1.00.81.10.9
Cocaine induced anxiety0.30.30.7-0.6-0.8-0.2-0.90.20.1-0.5-0.5
Post-drug Anxiety0.30.30.9-0.7-0.9-0.6-0.70.00.2-0.4-0.6
Baseline Anxiety0.30.30.6-0.4-0.4-0.7-0.10.8-0.6-0.2-0.6
Lifetime Intake0.20.31.30.10.11.1-0.10.40.30.80.2
Incentive Sensitization - Responses0.30.30.90.30.30.70.30.80.40.90.1
Incentive Sensitization - Breakpoint0.30.31.00.40.40.70.40.70.41.00.1
Progressive ratio test 1 active lever presses0.20.20.70.20.20.80.00.20.20.70.2
Progressive ratio test 1 breakpoint0.20.20.60.20.20.80.10.20.20.70.1
Progressive ratio test 1 inactive lever presses0.91.02.40.90.91.50.7-0.60.81.30.9
Progressive ratio test 2 active lever presses0.50.61.50.60.51.10.60.10.71.20.5
Progressive ratio test 2 breakpoint0.40.51.30.50.41.00.50.30.71.20.3
Progressive ratio test 2 inactive lever presses1.01.22.50.90.71.60.8-0.11.31.50.8
Total sessions with >9 infusions0.60.71.4-0.8-0.8-0.6-0.70.8-1.2-0.7-0.9
Short access day 1 total inactive lever presses0.70.82.30.60.51.50.30.01.01.30.6
Short access day 10 total inactive lever presses0.30.40.6-0.7-0.7-0.3-0.80.8-0.4-0.3-0.7
Short access day 1 total infusions0.50.52.00.40.41.4-0.0-0.00.21.20.5
Short access day 10 total infusions0.40.51.7-0.7-0.70.3-0.61.3-0.40.0-0.7
Short access total infusions0.30.31.60.10.01.2-0.30.40.00.90.1
Short access day 1 locomotion0.30.42.5-0.2-0.10.20.10.4-1.60.1-0.3
Short access day 10 total locomotion0.20.21.00.10.1-0.01.00.6-0.10.5-0.3
Short access total locomotion0.20.20.9-0.3-0.30.10.00.9-0.60.2-0.5
Compulsive drug intake0.50.51.3-0.8-0.6-0.6-1.20.8-0.5-0.5-0.7
One hour access (0.3 mA shock)0.10.10.5-0.1-0.10.4-0.20.7-0.30.0-0.3
One hour access (shock baseline)0.00.00.1-0.0-0.10.30.00.3-0.3-0.2-0.2
Number of responses in last shaping day0.10.10.50.2-0.0-0.00.7-0.2-0.00.3-0.1
Context. condit. distance diff. score2.42.95.1-1.7-1.8-1.7-2.31.0-1.7-1.8-1.5
Locomotion velocity, session 10.00.10.4-0.00.00.10.10.6-0.00.1-0.2
Locomotion distance, session 10.60.81.5-1.0-1.0-0.6-1.11.2-0.4-0.8-1.0
Locomotion velocity, session 20.00.00.10.00.2-0.0-0.2-0.1-0.40.00.1
Locomotion distance, session 20.00.00.20.0-0.00.3-0.10.10.40.1-0.0
Locomotion velocity, session 30.60.81.2-0.8-0.8-0.8-1.10.4-1.1-1.0-0.8
Locomotion distance, session 31.11.11.4-1.2-1.2-0.7-1.21.1-1.1-0.9-1.1
Stereotopy head waving bouts, day 31.51.82.41.51.41.21.2-1.51.21.31.4
Stereotopy head waving duration, day 30.40.50.80.80.70.60.4-0.50.90.80.7
Locomotion velocity, session 70.10.21.00.0-0.00.0-0.30.31.00.20.1
Locomotion distance, session 71.51.93.4-1.4-1.4-0.9-1.91.9-0.7-0.9-1.4
Stereotopy head waving bouts, day 71.61.83.31.41.51.11.5-1.80.71.21.5
Stereotopy head waving duration, day 72.32.94.71.81.81.21.9-2.21.11.51.8
Locomotion velocity, session 80.80.92.4-0.9-1.2-0.6-1.60.80.7-0.7-0.8
Locomotion distance, session 80.71.02.1-1.0-1.1-0.9-1.40.7-0.9-1.1-0.9
Degree of sensitization distance0.30.31.1-0.5-0.4-0.2-1.00.80.5-0.1-0.3
Degree of sensitization stereotypy1.21.32.51.21.20.81.4-1.60.30.91.2
Condit. Reinf. active minus inactive responses0.10.10.50.10.1-0.10.1-0.3-0.70.10.0
Condit. Reinf. active-inactive response ratio0.20.21.3-0.10.0-0.50.0-0.4-1.1-0.2-0.1
Condit. Reinf. active responses0.10.10.20.20.20.20.2-0.3-0.40.40.2
Condit. Reinf. inactive responses0.20.30.70.30.20.80.20.10.60.80.3
Incentive salience index mean0.10.10.30.20.20.10.4-0.6-0.30.40.2
Condit. Reinf. lever presses0.10.10.2-0.0-0.20.30.2-0.30.40.50.1
Time in familiar zone, hab. session 11.51.51.91.31.11.01.2-1.41.21.11.2
Time in novel zone, hab. session 10.30.20.4-0.4-0.3-0.5-0.20.6-0.6-0.6-0.5
Total zone transitions, hab. session 11.92.74.9-1.7-1.8-1.6-2.21.3-1.0-1.7-1.5
Total locomotion distance, hab. session 10.20.31.1-0.4-0.5-0.3-1.00.1-0.6-0.5-0.3
Locomotion velocity, hab. session 10.40.61.6-0.7-0.8-0.6-1.30.3-0.8-0.8-0.6
Time in familiar zone, hab. session 21.31.43.11.21.00.71.6-1.80.80.81.1
Time in novel zone, hab. session 20.20.20.7-0.20.0-0.1-0.60.8-0.3-0.2-0.2
Total zone transitions, hab. session 20.91.21.9-1.1-1.1-1.1-1.41.1-0.5-1.0-1.1
Total locomotion distance, hab. session 20.10.10.3-0.4-0.4-0.4-0.50.30.1-0.5-0.3
Locomotion velocity, hab. session 20.40.50.8-0.7-0.7-0.8-0.90.5-0.3-0.9-0.6
Novel to familiar place preference ratio0.70.71.4-0.9-0.8-0.4-1.00.8-1.2-0.7-0.8
Novelty place preference0.40.40.9-0.7-0.6-0.2-0.90.6-1.0-0.4-0.6
Time in novel zone, NPP test0.10.10.3-0.2-0.10.2-0.40.2-0.6-0.0-0.1
Total zone transitions, NPP test1.72.43.1-1.7-1.7-1.5-1.71.8-0.8-1.4-1.6
Total locomotion distance, NPP test0.30.40.7-0.6-0.7-0.4-0.90.8-0.1-0.5-0.6
Locomotion velocity, NPP test1.31.82.6-1.4-1.5-1.1-1.61.5-0.8-1.3-1.4
Pavlov. Cond. lever latency1.51.93.3-1.2-1.1-1.8-1.01.2-1.4-1.8-1.4
Pavlov. Cond. magazine entry latency3.84.95.62.32.32.42.4-2.31.42.32.3
Pavlov. Cond. change in total contacts2.72.94.41.51.52.01.5-2.11.11.91.8
Pavlov. Cond. index score2.63.45.01.71.62.21.7-1.61.62.21.8
Pavlov. Cond. latency score2.83.65.41.81.62.31.6-1.61.82.31.9
Pavlov. Cond. lever contacts1.01.22.20.80.71.50.8-0.91.31.41.0
Pavlov. Cond. magazine entry number4.45.57.0-2.4-2.3-2.6-2.42.3-1.5-2.6-2.4
Pavlov. Cond. intertrial magazine entries0.91.11.6-1.1-1.1-1.2-0.90.8-0.6-1.3-1.1
Pavlov. Cond. lever-magazine prob. diff.2.63.34.41.71.62.11.8-1.71.42.11.8
Pavlov. Cond. response bias1.92.33.51.51.41.91.4-1.60.71.81.6
Bone: apparent density0.40.71.20.90.91.01.1-0.50.10.90.7
Bone surface0.10.20.70.20.30.80.20.60.10.70.1
Bone volume0.20.40.90.60.61.00.60.40.30.90.4
Bone: connectivity density0.40.71.20.90.90.91.1-0.6-0.20.80.8
Bone: cortical apparent density4.45.88.42.52.32.92.4-2.02.02.62.3
Bone: cortical area0.60.92.40.80.91.60.40.10.91.40.8
Bone: cortical porosity1.61.74.8-1.0-0.9-1.4-0.61.1-2.2-1.4-1.2
Bone: cortical porosity1.31.43.4-1.0-0.9-1.3-0.61.0-1.8-1.3-1.1
Bone: cortical thickness1.72.84.91.61.72.21.0-1.31.42.01.8
Bone: cortical thickness1.11.32.21.21.51.30.6-1.2-0.51.21.3
Bone: cortical tissue density4.35.68.12.42.32.82.4-2.02.02.62.3
Bone: elastic displacement3.13.55.0-1.7-1.7-2.0-1.51.9-2.2-1.9-1.9
Bone: elastic work1.41.83.9-1.1-1.1-1.4-1.01.3-2.0-1.3-1.3
Bone: endosteal estimation2.14.59.8-2.1-1.9-1.7-2.03.1-1.7-1.7-2.3
Bone: endosteal perimeter0.71.33.8-1.2-1.0-0.9-0.82.0-0.8-0.8-1.3
Bone: final force1.72.75.11.61.72.31.0-0.61.82.11.6
Bone: final moment1.42.34.51.41.52.10.8-0.31.72.01.4
Bone: marrow area1.94.19.1-2.0-1.9-1.6-2.03.0-1.6-1.6-2.2
Bone: maximum diameter0.30.51.30.50.71.10.50.30.41.10.5
Bone: maximum force0.20.30.70.20.30.8-0.20.80.50.80.1
Bone: maximum moment0.20.31.3-0.00.10.6-0.51.10.30.6-0.1
Bone: minimum diameter0.40.61.9-0.7-0.6-0.2-0.81.4-0.8-0.6-0.8
Bone: periosteal estimation0.30.63.1-0.6-0.40.0-0.81.8-0.5-0.1-0.7
Bone: periosteal perimeter0.10.21.2-0.3-0.2-0.2-0.31.1-0.4-0.2-0.5
Bone: post-yield work0.30.51.6-0.7-0.6-0.2-1.30.9-0.0-0.3-0.5
Bone: stiffness0.71.22.50.80.91.60.4-0.41.31.51.0
Bone: tissue strength0.30.31.6-0.2-0.40.3-0.20.21.30.4-0.0
Bone: trabecular number1.21.93.51.51.51.41.9-1.20.21.41.3
Bone: trabecular spacing0.70.91.5-1.1-1.2-0.9-1.01.00.1-0.8-1.0
Bone: trabecular thickness0.30.30.70.70.80.40.7-0.20.30.40.6
Bone: trabecular tissue density0.50.61.50.50.51.0-0.2-0.51.21.10.7
Breakpoint value in progressive ratio session0.30.41.5-0.2-0.1-0.80.6-0.4-1.2-0.4-0.3
Distance traveled before self-admin2.83.04.1-1.7-1.5-1.1-1.82.0-2.0-1.8-1.8
Distance traveled after self-admin0.60.72.0-0.7-0.7-1.2-0.60.3-0.6-1.4-0.7
Delta time in closed arm before/after self-admin0.30.31.50.40.10.60.1-0.41.20.10.4
Delta time in open arm before/after self-admin0.10.10.20.00.1-0.30.4-0.10.10.40.0
Diff in mean of infusions in LGA sessions2.32.64.2-1.5-1.5-1.8-1.01.2-2.0-1.9-1.7
Extinction: sum of active levers before priming2.62.63.5-1.7-1.7-1.7-1.51.9-1.2-1.5-1.8
Active lever presses in extinction session 60.50.51.8-0.3-0.3-0.80.60.1-1.3-0.7-0.6
Delta distance traveled before/after self-admin1.61.74.11.31.20.31.4-2.01.50.61.4
Delta ambulatory time before/after self-admin1.21.32.81.10.9-0.11.3-1.71.50.51.1
Time in closed arm before self-admin0.40.41.20.50.7-0.30.9-1.1-0.50.30.6
Time in closed arm after self-admin0.40.41.70.30.2-0.80.4-1.3-0.3-0.50.3
Time in open arm before self-admin0.20.20.5-0.2-0.40.5-0.60.30.7-0.2-0.1
Time in open arm after self-admin0.20.20.5-0.1-0.10.3-0.20.70.70.6-0.1
Sum of active levers in priming session hrs 5-60.30.30.60.50.50.40.7-0.8-0.8-0.20.4
Time to tail flick, vehicle, before self-admin0.10.10.2-0.1-0.10.4-0.30.20.3-0.5-0.0
Time to tail flick, vehicle, after self-admin4.54.85.4-2.3-2.1-2.3-2.12.2-2.0-2.2-2.3
Time to tail flick, test, before self-admin1.00.91.6-1.0-0.8-1.2-0.91.1-0.9-0.9-0.9
Time to tail flick, test, after self-admin0.70.70.90.80.90.90.9-0.60.80.90.8
Delta time to tail flick, vehicle, before/after SA1.31.32.3-1.1-1.0-1.4-0.61.5-1.0-0.7-1.3
Delta time to tail flick, test, before/after SA0.80.71.60.80.91.30.6-0.80.60.80.9
Ambulatory time before self-admin3.94.15.2-2.0-1.9-1.2-2.32.3-2.2-2.1-2.0
Ambulatory time after self-admin1.01.12.2-1.0-1.1-1.3-1.00.9-0.5-1.5-1.0
Total heroin consumption0.40.51.60.60.8-0.01.2-0.9-0.60.00.4
Area under the delay curve0.40.41.2-0.7-0.7-0.4-1.10.4-0.7-0.4-0.6
Delay disc. indifference point, 0s delay0.10.10.5-0.2-0.1-0.1-0.30.3-0.70.1-0.3
Delay disc. indifference point, 16s delay0.40.41.1-0.5-0.5-0.6-0.8-0.3-1.1-0.5-0.3
Delay disc. indifference point, 2s delay0.10.10.20.10.20.20.20.5-0.40.4-0.1
Delay disc. indifference point, 24s delay0.90.92.6-1.0-0.9-0.4-1.60.9-1.0-0.6-0.8
Delay disc. indifference point, 4s delay0.10.10.4-0.1-0.10.0-0.40.0-0.7-0.1-0.1
Delay disc. indifference point, 8s delay0.50.51.3-0.7-0.8-0.1-1.11.0-0.2-0.2-0.7
Delay discount exponential model param0.40.51.30.70.70.41.1-0.40.70.50.6
Delay discount hyperbolic model param0.40.51.10.70.70.41.1-0.50.80.40.6
Fecal boli incidents, locomotor time 10.20.30.90.40.5-0.10.9-0.30.7-0.00.3
Change in fecal boli incidents, locomotor task0.40.41.30.50.50.10.4-1.10.40.60.7
Time >=10cm from walls, locomotor time 11.71.72.61.21.31.30.9-1.21.31.61.4
Bouts of movement, locomotor time 10.10.10.3-0.2-0.3-0.1-0.30.20.6-0.0-0.1
Total resting periods, locomotor time 10.30.30.5-0.6-0.7-0.6-0.50.60.3-0.5-0.5
Rest time, locomotor task time 10.20.20.5-0.4-0.4-0.50.00.4-0.2-0.7-0.4
Distance moved, locomotor task time 10.10.10.50.20.10.4-0.2-0.1-0.20.70.2
Vertical activity count, locomotor time 10.20.20.4-0.4-0.5-0.4-0.60.6-0.5-0.1-0.6
Time >=10cm from walls, locomotor time 22.93.13.61.91.91.71.7-1.91.11.81.9
Bouts of movement, locomotor time 20.91.01.3-1.0-1.1-0.8-1.10.8-1.1-0.8-1.0
Total resting periods, locomotor time 21.01.01.8-1.1-1.3-0.8-1.30.9-0.9-0.8-1.1
Rest time, locomotor task time 20.30.40.8-0.6-0.8-0.6-0.40.30.9-0.5-0.5
Distance moved, locomotor task time 20.10.10.4-0.10.00.1-0.50.5-0.70.3-0.2
Vertical activity count, locomotor time 21.31.42.9-1.1-0.9-0.8-1.21.4-1.7-1.1-1.2
Weight adjusted by age2.83.25.0-1.8-1.7-1.1-1.72.1-2.2-1.4-1.9
Seeking ratio, delayed vs. immediate footshock0.20.20.4-0.2-0.3-0.6-0.6-0.3-0.5-0.4-0.1
Locomotion in novel chamber0.30.31.50.40.60.30.1-0.4-1.20.30.3
Locomotion in novel chamber post-restriction0.10.10.30.20.20.20.60.30.00.0-0.0
Progressive ratio0.10.10.2-0.1-0.1-0.40.10.2-0.50.0-0.2
Food seeking constrained by brief footshock0.10.10.20.30.40.40.3-0.40.10.50.4
Seeking ratio, punishment vs. effort0.10.10.30.20.20.50.1-0.30.40.10.3
Run reversals in cocaine runway, females0.60.61.9-0.9-1.0-0.3-1.40.5-0.3-0.2-0.6
Run reversals in cocaine runway, males0.20.20.5-0.2-0.20.7-0.70.7-0.20.1-0.3
Latency to leave start box in cocaine runway0.20.20.5-0.5-0.7-0.6-0.40.10.3-0.6-0.5
Latency to leave start box in cocaine runway, F1.51.73.0-1.4-1.6-1.7-1.00.7-0.7-1.6-1.4
Latency to leave start box in cocaine runway, M0.60.61.00.80.81.00.4-0.60.51.00.8
Cd content in liver2.12.34.2-1.4-1.5-2.0-1.20.6-1.5-2.0-1.4
Co content in liver0.10.10.3-0.10.1-0.5-0.6-0.2-0.4-0.40.0
Cu content in liver0.10.10.2-0.3-0.3-0.3-0.2-0.0-0.4-0.1-0.2
Fe content in liver0.00.00.1-0.1-0.20.2-0.2-0.30.2-0.00.0
K content in liver5.95.97.22.52.72.42.5-2.71.22.42.6
Mg content in liver5.96.17.32.62.72.52.5-2.71.32.62.7
Mn content in liver13.815.817.94.24.14.14.0-4.23.03.84.2
Na content in liver0.60.71.70.80.70.91.3-0.20.51.00.5
Rb content in liver2.22.83.61.71.91.81.6-1.90.71.51.8
Se content in liver2.63.15.71.81.81.12.4-2.40.91.41.7
Sr content in liver0.20.10.30.40.60.30.1-0.50.20.30.5
Zn content in liver0.10.10.30.10.2-0.20.4-0.6-0.5-0.00.2