Hub : Genes

Trmu

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016465 0.12 0.06 1.1e-15 0.09 0.11 0.1 0.1 3.2e-10 5.4e-12 1.5e-11 1.3e-11
2 Adipose mRNA stability ENSRNOG00000016465 0.1 0.06 1.4e-07 0.04 0.04 0.04 0.04 3.0e-05 1.9e-05 3.9e-05 4.5e-05
3 BLA gene expression ENSRNOG00000016465 0.58 0.1 0.0e+00 0.52 0.53 0.54 0.55 5.7e-32 6.8e-33 4.8e-34 1.1e-34
4 BLA intron excision ratio chr7:116979040:116981437 0.18 0.15 4.2e-04 0.07 0.05 0.06 0.06 1.6e-04 1.8e-03 2.3e-04 3.5e-04
5 BLA mRNA stability ENSRNOG00000016465 0.16 0.08 2.3e-08 0.13 0.12 0.1 0.12 1.8e-07 4.9e-07 4.7e-06 5.6e-07
6 Brain gene expression ENSRNOG00000016465 0.67 0.1 0.0e+00 0.52 0.4 0.56 0.41 2.1e-55 1.1e-39 2.8e-62 3.5e-41
7 Brain isoform ratio ENSRNOT00000022511 0.05 0.03 7.6e-05 0.04 0.04 0.04 0.03 1.1e-04 9.4e-05 6.5e-05 4.1e-04
8 Brain isoform ratio ENSRNOT00000065283 0.05 0.03 8.6e-05 0.04 0.04 0.04 0.03 5.2e-05 1.1e-04 7.2e-05 6.4e-04
9 Brain intron excision ratio chr7:116979040:116981437 0.05 0.03 1.8e-05 0.05 0.05 0.05 0.05 1.5e-05 2.2e-05 4.1e-05 1.5e-05
10 Brain intron excision ratio chr7:116979040:116981496 0.02 0.02 7.0e-03 0 0.01 0 -0 3.2e-01 8.5e-02 1.7e-01 6.0e-01
11 Brain mRNA stability ENSRNOG00000016465 0.19 0.08 0.0e+00 0.24 0.22 0.23 0.11 2.4e-22 2.9e-20 1.5e-21 1.9e-10
12 IL gene expression ENSRNOG00000016465 0.7 0.13 1.7e-13 0.43 0.35 0.37 0.4 1.3e-11 2.7e-09 7.0e-10 8.2e-11
13 IL mRNA stability ENSRNOG00000016465 0.32 0.16 1.5e-05 0.09 0.19 0.16 0.19 2.9e-03 2.5e-05 1.4e-04 2.3e-05
14 LHb gene expression ENSRNOG00000016465 0.36 0.14 1.2e-05 0.07 0.11 0.08 0.08 1.1e-02 1.8e-03 6.4e-03 5.1e-03
15 Liver gene expression ENSRNOG00000016465 0.46 0.14 0.0e+00 0.33 0.33 0.33 0.32 4.7e-37 5.2e-37 8.4e-38 1.0e-36
16 NAcc gene expression ENSRNOG00000016465 0.53 0.08 0.0e+00 0.55 0.54 0.56 0.56 8.6e-49 1.2e-47 2.3e-49 1.8e-49
17 NAcc mRNA stability ENSRNOG00000016465 0.12 0.06 5.4e-11 0.12 0.14 0.07 0.13 1.9e-09 1.6e-10 3.4e-06 6.0e-10
18 OFC gene expression ENSRNOG00000016465 0.69 0.16 8.0e-08 0.29 0.17 0.31 0.22 1.3e-07 8.9e-05 4.5e-08 6.0e-06
19 OFC mRNA stability ENSRNOG00000016465 0.26 0.14 1.2e-04 0.07 0.09 0.18 0.16 1.1e-02 4.1e-03 5.6e-05 1.3e-04
20 PL gene expression ENSRNOG00000016465 0.77 0.04 0.0e+00 0.63 0.63 0.64 0.63 5.3e-61 1.0e-61 1.4e-63 8.2e-62
21 PL intron excision ratio chr7:116979040:116981437 0.08 0.05 1.2e-06 0.06 0.07 0.08 0.07 1.1e-05 3.5e-06 1.5e-06 7.4e-06
22 PL intron excision ratio chr7:116979040:116981492 0.03 0.02 4.4e-03 0.04 0.02 0.01 0.03 8.2e-04 6.5e-03 4.4e-02 3.3e-03
23 PL mRNA stability ENSRNOG00000016465 0.28 0.11 0.0e+00 0.19 0.23 0.23 0.24 1.3e-14 2.7e-17 1.0e-17 5.3e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
BMI with tail3.511.314.22.93.53.53.63.63.03.2-3.13.6-3.53.63.63.82.72.63.53.43.73.73.33.1-3.23.4
BMI without tail1.73.68.82.11.72.12.02.22.41.3-1.61.6-1.62.02.01.72.23.02.21.71.71.51.91.3-1.61.3
Body weight2.410.113.53.42.93.43.43.33.52.8-3.23.4-2.93.73.42.43.43.13.53.13.32.93.22.7-3.22.6
Epididymis fat weight0.20.41.30.80.50.60.50.50.60.7-0.81.1-0.50.50.50.20.70.40.60.80.60.40.70.6-0.80.3
Glucose0.30.42.5-0.4-0.1-0.4-0.8-0.7-1.00.6-0.50.10.2-0.8-0.8-0.2-0.8-1.6-0.6-0.2-0.3-0.4-0.60.0-0.6-0.4
Heart weight0.10.10.6-0.6-0.2-0.2-0.30.1-0.4-0.50.7-0.40.00.0-0.30.2-0.5-0.6-0.2-0.1-0.20.0-0.40.10.60.3
Left kidney weight13.839.650.06.36.36.56.86.66.65.6-5.86.2-6.37.16.85.46.35.46.76.56.56.26.56.1-5.86.2
Right kidney weight13.137.344.26.06.36.36.36.36.05.9-5.96.2-6.36.66.35.55.84.76.46.46.36.16.36.2-5.96.1
Tail length0.31.02.80.2-1.2-0.6-0.7-0.70.2-1.30.7-0.91.2-0.7-0.8-1.60.40.9-0.6-1.1-1.1-1.5-0.7-1.30.7-1.7
Length with tail0.20.62.01.40.30.70.60.51.20.5-1.11.0-0.30.90.6-0.61.41.00.80.60.5-0.00.70.4-1.0-0.2
Length without tail0.81.74.31.21.41.11.00.80.71.8-1.92.1-1.41.41.00.70.8-0.41.11.61.51.21.31.6-1.81.2
Liver weight, left0.30.50.80.50.70.70.80.80.70.4-0.40.7-0.80.90.80.90.60.60.70.70.80.80.70.5-0.40.8
Liver weight, right0.40.62.31.40.40.60.80.61.20.1-0.60.9-0.30.70.8-0.61.51.50.80.50.50.10.7-0.1-0.6-0.2
Parametrial fat weight0.40.82.4-0.3-0.9-0.8-0.6-0.5-0.2-1.41.1-0.81.0-0.8-0.7-0.8-0.10.8-0.6-1.0-0.9-1.1-0.9-1.51.2-1.2
Retroperitoneal fat weight2.16.910.03.12.62.82.62.62.82.5-2.83.2-2.52.82.61.83.02.82.72.72.62.12.62.4-2.72.0
Intraocular pressure0.30.42.51.00.30.50.50.50.90.2-0.50.8-0.20.40.4-0.31.11.60.50.30.40.00.4-0.2-0.6-0.2
Extensor digitorum longus weight0.41.72.81.31.11.41.31.51.51.0-1.01.3-1.21.51.30.91.41.71.41.31.31.11.51.1-1.01.1
Soleus weight0.20.61.30.50.90.70.70.70.40.9-0.81.0-0.90.70.71.20.30.40.70.90.90.90.80.8-0.70.9
Tibialis anterior weight0.00.20.8-0.7-0.4-0.3-0.1-0.1-0.2-0.60.9-0.70.30.2-0.10.2-0.5-0.2-0.2-0.3-0.20.0-0.2-0.10.80.2
Tibia length0.10.31.10.50.50.40.50.10.30.7-0.81.0-0.50.50.50.40.2-0.10.50.70.80.60.40.4-0.80.5
Number of licking bursts0.50.61.4-0.4-0.9-0.6-0.8-0.5-0.4-0.80.6-0.71.0-0.8-0.8-1.0-0.30.2-0.6-0.9-0.9-1.1-0.7-0.90.5-1.2
Food consumed during 24 hour testing period5.16.111.22.52.42.62.22.32.23.2-3.42.6-2.42.22.22.02.11.52.42.62.42.12.42.7-3.32.1
Times rat made contact with spout0.40.53.30.90.40.80.51.01.00.3-0.60.5-0.40.60.50.31.01.80.70.50.30.00.50.3-0.60.0
Mean time between licks in bursts0.81.12.2-1.0-1.5-1.1-0.7-1.0-0.5-1.21.1-1.51.4-1.1-0.7-1.2-0.8-0.4-0.8-1.2-1.2-1.1-0.8-1.21.1-1.0
Mean num. licks in bursts1.41.72.21.21.51.21.31.11.11.5-1.41.4-1.51.21.31.31.00.71.21.51.41.41.31.4-1.31.4
Std. dev. time between licks in bursts0.10.10.5-0.6-0.0-0.10.0-0.1-0.3-0.10.2-0.30.0-0.10.00.5-0.6-0.7-0.0-0.10.10.30.10.00.20.3
Water consumed over 24 hours2.53.05.21.71.71.81.61.61.62.2-2.31.7-1.71.51.61.41.61.11.71.81.61.51.82.0-2.31.6
Indifference point 0 sec0.00.00.2-0.3-0.2-0.1-0.1-0.2-0.3-0.20.10.10.2-0.2-0.20.1-0.4-0.4-0.2-0.2-0.0-0.0-0.2-0.40.2-0.1
Indifference point AUC0.20.20.8-0.4-0.3-0.5-0.4-0.7-0.5-0.50.5-0.40.4-0.4-0.4-0.4-0.4-0.9-0.3-0.5-0.3-0.3-0.4-0.50.5-0.4
Indifference point function ln k2.33.24.42.01.51.91.81.82.01.8-2.02.1-1.61.81.70.92.01.81.82.01.71.41.91.7-2.11.5
Indifference point function log k2.33.24.42.01.51.91.81.82.01.8-2.02.1-1.61.81.70.92.01.81.82.01.71.41.91.7-2.11.5
Delay discounting total patch changes 0 sec0.10.20.4-0.6-0.5-0.4-0.3-0.4-0.5-0.50.5-0.20.5-0.4-0.4-0.2-0.6-0.5-0.5-0.4-0.3-0.2-0.5-0.70.5-0.3
Delay discounting total patch changes 12 sec0.00.00.20.10.30.20.20.10.00.1-0.00.2-0.20.20.20.50.0-0.30.20.10.20.30.20.20.00.3
Delay discounting total patch changes 18 sec0.70.91.5-0.9-1.0-0.9-1.0-1.1-0.9-0.80.7-0.81.1-1.0-1.0-0.8-0.9-1.0-0.9-1.1-1.0-1.0-1.0-1.20.7-1.1
Delay discounting total patch changes 24 sec0.10.10.5-0.1-0.2-0.20.1-0.10.0-0.60.6-0.20.3-0.00.1-0.3-0.00.1-0.1-0.3-0.00.0-0.2-0.40.7-0.1
Delay discounting total patch changes 6 sec0.30.51.3-1.0-0.7-0.7-0.3-0.7-0.7-0.90.9-0.80.7-0.3-0.3-0.0-1.0-1.0-0.5-0.9-0.4-0.2-0.7-0.81.1-0.3
Delay discounting time to switch 0 sec0.10.10.8-0.4-0.0-0.3-0.2-0.0-0.4-0.20.4-0.90.1-0.2-0.20.3-0.4-0.2-0.3-0.4-0.4-0.1-0.20.00.60.0
Delay discounting water rate 0 sec0.40.61.30.70.80.90.70.70.70.8-0.81.1-0.80.90.70.70.60.40.80.90.90.80.70.7-1.00.7
Delay discounting water rate 12 sec0.10.20.80.70.00.60.40.30.70.2-0.60.9-0.10.30.3-0.30.60.80.40.40.50.10.5-0.2-0.6-0.1
Delay discounting water rate 18 sec0.10.10.60.3-0.00.30.10.10.20.4-0.60.5-0.00.00.1-0.00.10.20.20.30.2-0.00.30.1-0.7-0.0
Delay discounting water rate 24 sec0.40.51.50.60.80.70.60.40.40.9-0.91.2-0.80.40.50.70.40.20.60.90.80.70.60.8-1.10.7
Delay discounting water rate 6 sec0.20.41.30.0-0.6-0.4-0.8-0.7-0.3-0.3-0.1-0.20.6-0.7-0.8-1.1-0.0-0.0-0.5-0.5-0.6-0.9-0.5-0.8-0.1-1.1
Locomotor activity3.04.78.52.61.92.42.22.32.51.9-2.52.2-1.92.22.21.52.62.92.32.02.01.62.01.7-2.31.3
Locomotor testing distance0.50.82.81.10.61.00.91.11.20.7-1.00.8-0.60.90.90.51.21.71.00.80.70.60.90.5-0.90.4
Locomotor testing rearing0.81.23.51.40.71.31.01.51.60.8-1.00.9-0.81.21.00.31.51.91.31.00.80.61.20.8-1.10.5
Light reinforcement 10.71.43.61.40.71.31.51.51.90.2-0.50.8-0.71.51.40.21.71.91.40.81.10.91.30.3-0.50.7
Light reinforcement 23.34.36.02.32.02.32.12.32.21.9-2.02.5-2.02.12.11.32.21.92.22.22.22.02.31.7-2.11.7
Reaction time number correct0.30.50.9-0.5-0.7-0.6-0.6-0.6-0.4-0.80.7-0.80.7-0.8-0.6-0.7-0.4-0.2-0.6-0.8-0.7-0.7-0.8-0.90.6-0.8
Reaction time mean minus median0.40.51.0-0.5-0.7-0.9-0.6-1.0-0.6-0.70.5-0.90.8-0.7-0.6-0.5-0.5-0.5-0.7-0.9-0.7-0.7-0.8-0.90.5-0.7
Reaction time mean minus median AUC0.20.20.9-0.0-0.3-0.5-0.0-0.30.0-0.90.7-0.80.4-0.20.0-0.20.20.5-0.2-0.7-0.4-0.3-0.7-0.90.7-0.5
Reaction time num false alarms0.10.21.00.4-0.5-0.2-0.4-0.40.1-0.0-0.3-0.00.5-0.5-0.3-1.00.30.2-0.2-0.3-0.4-0.9-0.1-0.5-0.3-0.8
Reaction time num false alarms AUC0.20.31.60.5-0.5-0.3-0.5-0.60.1-0.1-0.30.00.5-0.6-0.4-1.30.40.2-0.3-0.3-0.5-1.0-0.1-0.5-0.2-0.9
Reaction time trials correct on left0.30.50.9-0.5-0.7-0.6-0.6-0.6-0.4-0.80.7-0.80.7-0.8-0.6-0.7-0.4-0.2-0.6-0.8-0.7-0.7-0.8-0.90.6-0.8
Reaction time trials on left0.30.50.9-0.5-0.7-0.7-0.6-0.6-0.4-0.80.7-0.80.8-0.8-0.6-0.7-0.4-0.2-0.6-0.8-0.7-0.7-0.8-1.00.6-0.8
Reaction time mean1.82.53.9-1.9-1.2-1.8-1.6-1.8-2.0-1.31.5-1.71.3-1.6-1.5-0.7-2.0-2.0-1.7-1.5-1.4-1.0-1.8-1.21.5-1.0
Reaction time mean AUC2.12.84.0-2.0-1.4-1.9-1.6-1.8-2.0-1.51.7-1.91.4-1.7-1.6-0.8-2.0-1.9-1.8-1.7-1.5-1.1-1.9-1.41.7-1.1
Median of all reaction times2.12.95.3-2.2-1.3-1.9-1.7-1.8-2.2-1.41.7-1.81.3-1.7-1.7-0.6-2.3-2.3-1.9-1.6-1.5-1.0-1.9-1.21.7-1.0
Reaction time omissions1.01.42.4-1.5-1.2-1.3-1.0-1.3-1.3-1.11.3-1.41.2-1.3-0.9-0.6-1.5-1.5-1.3-1.3-1.1-0.7-1.2-0.91.2-0.7
Reaction time false alarm rate0.10.10.50.7-0.00.1-0.1-0.20.40.4-0.70.50.0-0.1-0.0-0.60.60.40.10.2-0.0-0.40.30.2-0.6-0.3
Reaction time premature initiation rate0.70.93.10.21.30.70.50.5-0.21.5-1.10.8-1.20.70.51.8-0.2-0.60.50.90.91.20.71.4-1.01.3
Reaction time premature initiations0.20.31.4-0.20.70.2-0.00.1-0.50.8-0.50.1-0.60.1-0.01.2-0.4-0.80.10.30.30.60.10.7-0.50.6
Std. dev. reaction times0.91.32.1-1.1-1.0-1.4-1.1-1.4-1.2-1.11.0-1.31.1-1.2-1.1-0.8-1.1-1.1-1.2-1.2-1.1-1.0-1.2-1.11.0-1.0
Reaction time trials completed0.30.50.9-0.5-0.7-0.7-0.6-0.6-0.4-0.80.7-0.80.8-0.8-0.6-0.7-0.4-0.2-0.6-0.8-0.7-0.7-0.8-1.00.6-0.8
Reaction time trials AUC0.10.20.5-0.3-0.4-0.4-0.4-0.3-0.2-0.50.4-0.50.5-0.6-0.4-0.4-0.20.0-0.4-0.5-0.5-0.5-0.5-0.70.3-0.6
Social response proportion1.31.42.81.21.11.41.01.21.11.5-1.61.2-1.11.11.00.81.10.51.21.31.00.91.31.5-1.71.0
Social responses1.51.93.31.71.01.71.41.61.81.3-1.51.1-1.01.41.40.51.71.61.61.21.10.91.61.1-1.50.9
Social time0.40.51.2-0.3-1.1-0.6-0.5-0.8-0.1-0.70.4-0.61.1-0.6-0.5-1.0-0.20.1-0.5-0.8-0.8-1.0-0.4-1.00.3-1.0
Conditioned locomotion0.10.10.10.20.20.30.40.40.3-0.00.00.2-0.20.30.4-0.10.30.20.40.20.30.40.40.2-0.00.2
Cocaine response after cond. corrected0.10.10.40.3-0.10.30.30.20.50.3-0.50.60.10.40.3-0.10.20.60.30.20.30.00.3-0.2-0.5-0.1
Cocaine response after cond. not corrected0.10.10.80.2-0.50.00.1-0.00.5-0.2-0.10.30.40.20.1-0.60.30.90.1-0.1-0.0-0.40.1-0.7-0.1-0.4
Cocaine response before conditioning0.40.50.9-0.3-0.7-0.6-0.6-0.6-0.4-0.90.8-0.60.7-0.7-0.6-1.0-0.2-0.0-0.6-0.7-0.7-0.8-0.7-0.90.8-0.8
Saline control response0.10.21.20.20.00.00.0-0.3-0.00.7-0.70.7-0.10.10.0-0.7-0.0-1.10.10.40.30.00.50.3-0.70.1
Condit. Reinf. active minus inactive responses0.30.41.20.50.80.7-0.00.60.11.1-1.11.0-0.80.5-0.00.80.20.20.30.80.50.30.20.7-1.10.3
Condit. Reinf. active-inactive response ratio0.10.10.30.10.20.3-0.30.3-0.10.5-0.50.5-0.20.2-0.30.3-0.10.10.00.30.0-0.1-0.10.2-0.4-0.1
Condit. Reinf. active responses1.42.03.31.31.71.51.01.41.01.8-1.71.8-1.61.51.01.61.00.91.31.61.41.21.11.5-1.81.3
Condit. Reinf. inactive responses3.13.84.51.92.12.02.11.91.91.9-1.92.0-2.12.12.11.91.71.62.02.02.12.02.01.8-1.92.0
Condit. Reinf. lever presses0.81.12.20.91.11.11.01.21.00.9-0.91.1-1.11.51.01.00.91.01.11.11.01.00.91.1-0.91.0
Condit. Reinf. lever reinforcers received0.91.32.41.01.41.20.71.10.71.5-1.51.5-1.41.20.71.30.70.61.01.31.11.00.81.2-1.51.0
Pavlov. Cond. lever latency0.20.30.5-0.5-0.6-0.6-0.2-0.6-0.4-0.60.5-0.70.6-0.7-0.2-0.6-0.3-0.6-0.4-0.6-0.4-0.3-0.3-0.60.6-0.4
Pavlov. Cond. magazine entry latency1.01.13.4-1.6-0.5-1.1-1.2-1.0-1.7-0.61.1-1.00.5-0.9-1.20.3-1.8-1.8-1.1-0.8-0.8-0.3-1.3-0.41.1-0.3
Pavlov. Cond. change in total contacts0.30.41.7-0.20.80.4-0.20.4-0.61.1-0.70.4-0.70.2-0.21.3-0.5-0.60.00.50.30.5-0.10.9-0.80.5
Pavlov. Cond. index score0.10.10.5-0.50.2-0.1-0.4-0.0-0.60.20.1-0.0-0.20.0-0.40.6-0.7-0.7-0.30.0-0.10.1-0.50.30.10.1
Pavlov. Cond. latency score0.10.10.7-0.50.40.1-0.20.2-0.50.30.00.1-0.40.2-0.20.8-0.6-0.7-0.10.20.10.4-0.30.4-0.00.4
Pavlov. Cond. lever contacts0.40.61.00.40.90.80.50.80.31.0-0.80.9-0.90.90.51.00.30.20.60.90.80.80.51.0-0.80.9
Pavlov. Cond. magazine entry number0.30.31.10.90.00.50.70.31.00.2-0.50.6-0.00.40.7-0.41.01.00.60.30.50.10.8-0.1-0.50.1
Pavlov. Cond. intertrial magazine entries0.70.91.50.71.20.80.90.70.51.0-0.91.2-1.10.80.91.20.50.10.81.11.21.20.91.0-0.91.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.50.1-0.2-0.5-0.0-0.60.00.3-0.1-0.1-0.0-0.50.4-0.6-0.5-0.3-0.0-0.20.0-0.50.10.20.0
Pavlov. Cond. response bias0.10.10.7-0.20.50.3-0.10.3-0.20.6-0.30.3-0.50.3-0.10.9-0.3-0.30.10.40.30.4-0.00.6-0.30.5
Conditioned reinforcement - actives0.30.31.10.1-0.6-0.7-0.5-0.5-0.0-0.40.40.10.6-0.5-0.5-1.10.10.2-0.4-0.3-0.5-0.8-0.3-0.90.2-0.8
Conditioned reinforcement - inactives0.20.21.20.70.40.20.20.20.40.8-0.61.1-0.50.20.2-0.20.50.20.30.70.50.10.70.4-0.70.3
Conditioned locomotion1.51.82.91.61.11.31.31.31.61.4-1.51.7-1.21.31.30.81.51.61.51.41.41.01.60.9-1.61.0
Intermittent access intake day 1-15 change0.30.30.90.1-0.1-0.3-0.6-0.6-0.40.9-0.90.70.0-0.6-0.6-0.6-0.2-0.7-0.30.3-0.2-0.60.30.5-0.8-0.3
Intermittent access intake escalation0.30.31.40.50.20.1-0.2-0.10.11.2-1.11.1-0.3-0.2-0.2-0.40.2-0.30.10.70.3-0.20.70.7-1.10.1
Intermittent access intake escalation 20.40.41.9-0.4-0.2-0.5-0.9-0.9-0.90.9-0.80.40.2-0.9-0.9-0.4-0.8-1.4-0.50.1-0.3-0.60.20.3-0.7-0.3
Intermitt. access day 1 inactive lever presses0.60.71.50.31.10.70.80.80.11.0-0.80.7-1.10.80.81.10.1-0.40.70.81.01.20.50.9-0.51.2
Intermitt. access day 15 inactive lever presses2.83.15.41.31.91.71.51.71.02.3-2.12.2-2.01.51.51.80.90.31.62.02.01.91.71.9-2.12.0
Intermitt. access escalation Index0.30.30.50.40.30.60.60.60.60.5-0.40.5-0.40.60.60.50.50.60.60.60.60.50.70.7-0.30.6
Intermittent access day 1 total infusions1.61.83.81.91.11.31.21.31.61.3-1.31.9-1.21.21.20.41.91.81.31.41.30.81.40.9-1.60.7
Intermittent access day 15 total infusions1.51.75.01.71.01.00.80.91.21.8-1.72.2-1.10.80.80.11.51.01.11.61.20.51.51.2-2.00.7
Intermittent access terminal intake (last 3 days)2.83.17.72.21.61.51.21.31.62.4-2.42.8-1.61.21.10.71.81.31.52.11.61.02.01.6-2.61.1
Intermittent access total infusions2.62.96.62.21.61.51.31.41.72.1-2.12.6-1.61.31.30.71.91.41.62.01.71.01.91.5-2.41.1
Intermittent access day 1 locomotion0.60.62.11.30.50.60.50.61.00.6-0.81.2-0.50.50.5-0.21.31.40.60.70.60.10.60.2-1.00.0
Intermittent access day 15 total locomotion1.51.63.91.91.01.00.91.01.51.2-1.32.0-1.10.90.9-0.11.81.81.01.41.10.51.31.0-1.50.5
Intermittent access total locomotion1.51.74.51.81.31.10.91.01.31.6-1.62.1-1.30.90.90.41.61.51.11.61.20.71.41.1-1.80.7
Intermittent access standard deviation0.50.51.70.60.90.50.10.2-0.01.2-1.01.3-0.90.10.10.50.2-0.40.30.90.70.40.71.0-1.10.6
Cocaine induced anxiety2.52.85.81.12.11.61.81.61.11.8-1.51.5-2.01.81.82.40.90.91.71.71.92.21.41.7-1.42.1
Post-drug Anxiety1.92.16.60.31.81.31.51.30.31.5-1.21.1-1.81.51.52.60.1-0.31.31.41.72.20.81.6-0.92.1
Baseline Anxiety1.31.42.1-1.3-1.3-1.2-1.3-1.3-1.2-1.11.1-0.91.2-1.3-1.3-1.2-1.3-1.5-1.2-1.0-1.1-1.2-1.0-0.91.2-1.1
Lifetime Intake2.83.26.32.31.61.61.41.51.92.1-2.12.5-1.71.41.40.72.11.71.72.01.71.12.01.5-2.41.1
Incentive Sensitization - Responses0.40.41.20.31.00.30.20.2-0.31.1-0.71.1-1.00.20.20.70.1-0.40.20.80.70.70.50.7-1.00.7
Incentive Sensitization - Breakpoint0.50.51.40.41.10.40.30.3-0.11.1-0.71.2-1.10.30.30.80.2-0.30.30.80.80.80.60.8-1.10.8
Progressive ratio test 1 active lever presses0.70.84.51.40.40.70.70.81.30.3-0.41.2-0.40.70.6-0.11.52.10.80.70.60.20.7-0.1-0.80.1
Progressive ratio test 1 breakpoint0.70.74.31.30.30.60.60.81.30.2-0.41.1-0.30.60.6-0.11.42.10.70.60.60.10.6-0.1-0.70.0
Progressive ratio test 1 inactive lever presses0.50.51.40.90.60.60.81.01.00.2-0.10.7-0.60.80.80.11.11.20.80.60.70.60.50.2-0.20.5
Progressive ratio test 2 active lever presses0.20.21.40.50.70.10.00.2-0.00.7-0.41.2-0.70.00.00.10.40.20.10.60.50.30.40.2-0.90.3
Progressive ratio test 2 breakpoint0.20.21.30.50.70.20.10.2-0.00.7-0.41.1-0.70.10.10.20.30.20.20.60.50.40.40.3-0.80.3
Progressive ratio test 2 inactive lever presses0.91.13.41.11.30.70.80.80.61.3-1.01.9-1.30.80.80.50.90.40.91.31.21.01.21.0-1.21.0
Total sessions with >9 infusions2.32.54.92.21.11.61.31.52.01.8-2.01.8-1.21.31.30.32.11.81.61.71.30.71.91.2-2.10.8
Short access day 1 total inactive lever presses3.64.04.92.01.81.82.12.22.22.0-1.82.2-1.92.12.11.52.01.92.22.12.11.82.21.7-1.91.9
Short access day 10 total inactive lever presses0.70.81.30.61.20.90.80.80.41.1-1.20.8-1.10.80.91.00.4-0.20.80.91.01.10.70.9-0.91.0
Short access day 1 total infusions1.82.04.02.01.11.41.21.41.81.4-1.71.4-1.11.21.20.42.01.71.41.41.10.61.41.2-1.90.8
Short access day 10 total infusions2.73.05.02.21.41.71.61.82.01.8-1.92.2-1.41.61.50.72.12.01.81.81.71.21.91.2-2.21.1
Short access total infusions4.65.17.52.72.12.22.12.22.52.4-2.42.7-2.12.12.11.32.62.32.32.42.21.72.51.9-2.71.7
Short access day 1 locomotion0.20.20.60.50.30.40.20.40.40.7-0.80.5-0.40.20.20.00.40.30.30.50.30.10.50.4-0.80.3
Short access day 10 total locomotion0.40.43.80.9-0.20.30.20.51.1-0.40.20.20.20.20.2-0.81.11.90.30.10.0-0.30.4-0.4-0.1-0.4
Short access total locomotion1.61.72.41.51.11.31.21.41.51.3-1.31.5-1.21.21.20.61.51.51.31.41.31.01.50.9-1.51.0
Compulsive drug intake0.40.41.7-1.0-0.4-0.4-0.5-0.4-0.9-0.30.5-0.90.3-0.5-0.50.0-1.0-1.3-0.5-0.5-0.5-0.1-0.50.10.70.0
One hour access (0.3 mA shock)0.50.51.41.10.70.50.50.50.80.7-0.71.2-0.70.50.5-0.21.00.40.70.80.70.41.00.6-1.10.4
One hour access (shock baseline)1.21.43.31.70.90.90.90.91.41.2-1.31.8-0.90.90.9-0.11.61.21.11.31.10.61.50.7-1.70.5
Number of responses in last shaping day0.10.10.30.2-0.00.30.30.30.40.4-0.5-0.2-0.00.30.30.10.30.30.30.10.10.10.30.3-0.40.2
Context. condit. distance diff. score1.21.52.31.41.31.11.41.01.31.0-0.91.2-1.41.41.40.71.51.01.21.31.31.21.21.5-0.91.3
Locomotion velocity, session 11.01.13.51.30.51.11.11.01.51.0-1.30.8-0.60.91.10.31.41.91.10.80.70.41.20.4-1.30.5
Locomotion distance, session 10.30.41.1-0.2-0.9-0.5-0.3-0.5-0.1-0.60.4-0.80.8-0.5-0.3-1.1-0.10.1-0.4-0.7-0.7-0.8-0.3-0.80.5-0.7
Locomotion velocity, session 22.93.49.12.21.62.01.92.02.21.5-1.91.9-1.51.71.91.32.23.02.01.61.61.21.81.0-1.81.1
Locomotion distance, session 20.10.10.3-0.6-0.3-0.3-0.2-0.3-0.4-0.30.4-0.40.3-0.4-0.20.2-0.6-0.3-0.3-0.4-0.2-0.1-0.4-0.40.5-0.0
Locomotion velocity, session 31.41.68.52.10.81.11.21.11.90.5-1.10.9-0.71.11.2-0.22.32.91.30.80.70.21.10.4-1.10.1
Locomotion distance, session 30.20.31.20.4-0.4-0.2-0.2-0.20.3-0.50.1-0.30.5-0.2-0.2-1.10.60.9-0.1-0.4-0.5-0.7-0.3-0.70.1-0.9
Stereotopy head waving bouts, day 31.11.33.31.21.11.11.31.21.40.8-0.90.6-1.11.31.31.21.31.81.21.00.91.01.11.1-0.91.0
Stereotopy head waving duration, day 32.73.35.81.81.61.92.12.12.11.4-1.41.1-1.72.12.11.72.02.41.91.61.61.61.91.8-1.41.8
Locomotion velocity, session 71.21.45.11.61.01.21.21.41.60.4-0.60.8-1.01.41.30.51.82.31.30.80.90.71.10.6-0.60.6
Locomotion distance, session 70.10.10.80.60.20.20.20.20.4-0.1-0.00.5-0.10.20.2-0.30.60.90.20.20.2-0.10.3-0.1-0.0-0.2
Stereotopy head waving bouts, day 71.41.63.51.51.21.31.31.41.50.9-1.00.9-1.21.41.40.71.71.91.31.11.11.01.21.1-1.01.0
Stereotopy head waving duration, day 70.50.71.81.00.70.81.00.91.10.4-0.50.5-0.71.01.00.51.11.40.90.70.70.60.80.7-0.50.7
Locomotion velocity, session 85.46.57.42.72.72.62.62.42.52.6-2.62.6-2.72.52.62.42.52.52.62.72.62.42.52.5-2.62.4
Locomotion distance, session 80.50.71.21.10.90.70.90.50.90.7-0.70.9-0.90.80.90.31.10.90.80.80.90.70.80.8-0.70.7
Degree of sensitization distance1.01.02.10.71.30.90.80.90.51.2-1.01.4-1.30.90.81.30.50.30.81.21.21.21.01.2-1.01.2
Degree of sensitization stereotypy0.60.71.21.00.80.90.80.91.00.7-0.80.7-0.80.80.80.41.01.10.90.80.70.60.80.8-0.80.6
Condit. Reinf. active minus inactive responses0.50.51.2-0.6-0.5-0.8-0.9-1.1-0.9-0.1-0.0-0.40.6-0.9-0.9-0.5-0.8-1.1-0.8-0.6-0.6-0.7-0.9-0.50.0-0.8
Condit. Reinf. active-inactive response ratio1.31.42.4-1.1-1.0-1.3-1.4-1.4-1.5-0.80.8-1.11.1-1.5-1.4-0.9-1.2-1.6-1.4-1.1-1.2-1.2-1.4-0.80.7-1.2
Condit. Reinf. active responses1.01.31.9-0.8-1.2-1.3-1.2-1.4-1.0-0.90.8-0.81.2-1.2-1.2-1.1-0.9-0.6-1.2-1.1-1.1-1.3-1.4-1.40.8-1.4
Condit. Reinf. inactive responses0.40.41.4-0.2-0.8-0.7-0.5-0.6-0.1-0.90.7-0.30.8-0.4-0.5-0.9-0.10.6-0.5-0.6-0.6-0.8-0.7-1.20.8-0.9
Incentive salience index mean0.10.10.60.3-0.2-0.2-0.2-0.6-0.00.5-0.80.40.2-0.3-0.2-0.40.1-0.2-0.1-0.0-0.1-0.4-0.1-0.2-0.7-0.5
Condit. Reinf. lever presses0.50.71.81.30.40.70.80.41.20.9-1.31.1-0.30.80.8-0.21.21.10.90.70.70.21.00.3-1.30.1
Time in familiar zone, hab. session 11.51.42.11.01.01.41.41.51.31.1-1.01.1-1.01.21.41.01.11.21.31.11.21.11.40.9-1.01.2
Time in novel zone, hab. session 10.10.10.6-0.4-0.3-0.4-0.4-0.5-0.40.2-0.1-0.40.3-0.3-0.4-0.2-0.4-0.8-0.3-0.2-0.4-0.3-0.40.1-0.1-0.2
Total zone transitions, hab. session 11.82.53.4-1.7-1.7-1.7-1.4-1.7-1.5-1.61.7-1.81.6-1.5-1.4-1.4-1.6-1.7-1.6-1.7-1.5-1.3-1.7-1.31.8-1.2
Total locomotion distance, hab. session 10.10.10.60.1-0.3-0.30.1-0.20.2-0.40.3-0.30.3-0.00.1-0.80.30.2-0.1-0.3-0.2-0.2-0.1-0.30.4-0.2
Locomotion velocity, hab. session 10.10.10.50.2-0.3-0.30.1-0.20.3-0.50.3-0.30.3-0.00.1-0.70.40.4-0.1-0.3-0.2-0.2-0.0-0.40.4-0.3
Time in familiar zone, hab. session 20.10.10.40.4-0.20.10.20.10.5-0.0-0.20.40.20.10.2-0.60.40.60.30.10.1-0.20.3-0.3-0.0-0.2
Time in novel zone, hab. session 20.50.51.7-0.8-0.4-0.6-0.9-0.7-1.0-0.20.3-0.90.4-0.7-0.9-0.2-0.9-1.3-0.8-0.6-0.7-0.5-0.8-0.10.2-0.4
Total zone transitions, hab. session 20.30.41.00.10.60.50.70.50.30.6-0.30.4-0.60.60.70.80.1-0.10.60.60.71.00.50.6-0.21.0
Total locomotion distance, hab. session 20.10.10.30.30.40.30.50.30.30.4-0.30.4-0.40.40.50.30.30.10.40.40.50.50.40.3-0.30.4
Locomotion velocity, hab. session 20.10.10.20.30.40.30.40.30.30.3-0.30.4-0.40.30.40.20.30.10.40.30.40.40.40.2-0.20.4
Novel to familiar place preference ratio0.20.21.1-0.4-0.7-0.3-0.4-0.3-0.2-0.40.4-1.00.6-0.2-0.4-0.5-0.3-0.2-0.3-0.5-0.7-0.6-0.2-0.20.3-0.4
Novelty place preference0.10.10.6-0.1-0.5-0.0-0.1-0.10.2-0.20.1-0.80.40.2-0.1-0.50.10.1-0.0-0.3-0.5-0.50.10.1-0.0-0.2
Time in novel zone, NPP test0.10.10.8-0.1-0.5-0.1-0.1-0.10.2-0.20.2-0.90.50.1-0.1-0.50.10.2-0.1-0.3-0.6-0.50.10.00.1-0.3
Total zone transitions, NPP test1.01.42.8-1.3-1.1-1.3-1.0-1.1-1.2-1.41.5-1.21.1-1.1-1.0-1.1-1.1-1.2-1.2-1.1-1.0-0.8-1.1-1.21.7-0.8
Total locomotion distance, NPP test0.20.20.7-0.3-0.3-0.6-0.4-0.4-0.4-0.70.7-0.30.4-0.5-0.4-0.6-0.3-0.2-0.5-0.5-0.4-0.3-0.4-0.70.8-0.4
Locomotion velocity, NPP test0.20.31.0-0.4-0.4-0.6-0.4-0.4-0.4-0.90.9-0.30.5-0.6-0.4-0.7-0.3-0.1-0.5-0.6-0.4-0.4-0.5-0.81.0-0.5
Pavlov. Cond. lever latency0.30.31.5-0.8-0.1-0.4-0.4-0.1-0.7-0.81.2-0.80.1-0.4-0.30.4-0.6-0.5-0.5-0.5-0.40.1-0.6-0.21.20.1
Pavlov. Cond. magazine entry latency0.30.41.1-0.6-0.6-0.5-0.8-0.8-0.80.3-0.3-0.10.6-0.7-0.8-0.4-0.9-1.0-0.6-0.4-0.5-0.6-0.4-0.4-0.3-0.6
Pavlov. Cond. change in total contacts0.20.21.4-0.00.10.2-0.2-0.1-0.31.1-1.20.5-0.0-0.1-0.30.3-0.4-0.70.00.20.1-0.00.00.4-1.2-0.0
Pavlov. Cond. index score0.10.10.90.1-0.10.0-0.2-0.3-0.10.8-0.90.60.1-0.2-0.2-0.2-0.2-0.40.00.20.1-0.20.10.0-0.9-0.2
Pavlov. Cond. latency score0.20.21.30.40.10.30.1-0.10.20.9-1.10.7-0.10.10.0-0.10.1-0.20.30.40.3-0.00.40.2-1.1-0.0
Pavlov. Cond. lever contacts0.50.62.31.10.20.60.50.20.91.0-1.51.2-0.20.50.5-0.30.90.70.70.70.60.00.80.3-1.5-0.1
Pavlov. Cond. magazine entry number0.20.30.80.40.40.30.70.60.7-0.40.5-0.2-0.40.70.70.40.70.90.40.20.30.50.30.30.50.6
Pavlov. Cond. intertrial magazine entries1.11.32.0-1.2-1.1-1.4-1.2-1.4-1.2-1.01.0-1.01.1-1.2-1.2-0.9-1.2-1.4-1.3-1.1-1.1-1.0-1.2-1.11.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.6-0.0-0.3-0.1-0.4-0.5-0.30.5-0.70.40.3-0.4-0.4-0.4-0.3-0.5-0.2-0.0-0.1-0.4-0.1-0.2-0.8-0.5
Pavlov. Cond. response bias0.20.21.10.3-0.20.1-0.2-0.20.10.8-1.00.80.2-0.2-0.2-0.40.0-0.00.10.20.1-0.40.2-0.2-1.0-0.4
Bone: apparent density0.81.31.8-1.3-1.2-1.2-1.3-1.2-1.2-0.91.0-1.11.2-1.0-1.3-0.8-1.3-0.9-1.3-1.1-1.2-1.2-1.3-1.00.9-1.0
Bone surface0.20.40.7-0.8-0.9-0.6-0.8-0.6-0.5-0.50.4-0.80.8-0.4-0.8-0.4-0.8-0.1-0.7-0.7-0.8-0.8-0.7-0.50.5-0.7
Bone volume0.50.81.1-0.9-1.0-0.9-1.0-0.8-0.7-0.80.8-1.01.0-0.7-1.0-0.7-0.9-0.3-0.9-0.9-1.0-1.0-0.9-0.80.8-0.9
Bone: connectivity density0.50.81.4-0.8-1.1-0.8-1.1-0.8-0.7-0.70.6-0.91.0-0.9-1.1-0.6-0.8-0.1-0.9-0.9-1.1-1.2-1.0-0.90.6-1.1
Bone: cortical apparent density1.01.42.2-1.3-1.0-1.2-1.1-1.2-1.4-1.01.2-1.41.0-1.4-1.2-0.8-1.3-1.5-1.3-1.2-1.2-0.9-1.2-0.81.2-0.8
Bone: cortical area1.62.43.81.31.61.51.41.31.21.9-1.91.7-1.61.71.41.41.10.31.51.71.61.61.61.8-1.81.6
Bone: cortical porosity1.31.43.21.01.31.00.90.60.71.8-1.81.6-1.31.20.91.10.6-0.11.01.41.31.21.11.4-1.71.2
Bone: cortical porosity1.31.43.00.91.31.00.90.70.71.7-1.71.5-1.21.10.91.10.6-0.11.01.31.21.21.11.4-1.71.2
Bone: cortical thickness0.10.21.5-0.30.30.0-0.0-0.2-0.40.6-0.40.2-0.30.2-0.00.4-0.4-1.2-0.00.30.30.40.20.6-0.40.4
Bone: cortical thickness2.12.54.61.11.71.51.41.30.92.2-1.91.5-1.71.41.51.60.8-0.31.41.71.71.81.72.1-1.91.8
Bone: cortical tissue density0.81.01.8-1.1-0.8-1.0-1.0-1.0-1.2-0.91.1-1.20.9-1.2-1.0-0.7-1.1-1.3-1.1-1.1-1.0-0.7-1.0-0.71.0-0.7
Bone: elastic displacement0.30.30.70.70.20.40.80.30.80.4-0.60.6-0.20.50.80.00.70.80.60.40.50.30.8-0.1-0.70.3
Bone: elastic work3.54.65.72.12.22.12.21.92.02.3-2.32.2-2.22.22.22.01.91.52.22.32.22.12.32.1-2.42.1
Bone: endosteal estimation2.45.16.62.42.22.42.32.42.42.1-2.22.3-2.22.62.31.82.32.42.42.32.32.02.32.2-2.22.1
Bone: endosteal perimeter3.26.68.52.82.42.72.52.62.72.7-2.92.7-2.42.82.61.72.72.32.72.62.52.22.62.5-2.82.2
Bone: final force1.22.03.90.61.61.21.31.10.81.6-1.21.4-1.61.71.41.90.5-0.21.31.61.71.91.41.9-1.22.0
Bone: final moment1.62.75.20.71.81.51.61.31.01.8-1.41.5-1.82.01.62.20.6-0.11.51.81.92.21.62.1-1.32.3
Bone: marrow area2.45.16.52.32.22.32.32.42.42.1-2.12.3-2.22.62.31.82.32.42.32.32.32.02.32.2-2.12.1
Bone: maximum diameter6.311.514.53.43.43.53.33.33.23.8-3.83.7-3.43.63.32.83.12.43.53.63.53.23.53.5-3.83.2
Bone: maximum force1.73.05.80.92.01.61.71.41.02.0-1.51.5-2.02.01.72.30.7-0.01.61.92.02.31.72.3-1.52.4
Bone: maximum moment2.23.97.31.02.21.82.01.61.32.2-1.71.7-2.22.32.02.70.80.11.82.12.32.61.92.5-1.72.7
Bone: minimum diameter1.52.74.12.01.51.71.51.51.81.8-2.02.0-1.61.91.50.71.81.41.71.81.61.21.71.6-2.01.2
Bone: periosteal estimation2.85.77.32.32.42.52.42.42.32.6-2.52.5-2.42.72.42.02.21.82.42.52.52.32.52.6-2.52.4
Bone: periosteal perimeter4.06.710.12.82.42.72.42.52.62.8-3.22.9-2.42.82.51.72.62.12.72.72.52.12.72.5-3.12.1
Bone: post-yield work0.20.31.1-1.1-0.3-0.4-0.5-0.2-0.8-0.30.6-0.90.3-0.2-0.50.5-1.0-0.9-0.4-0.4-0.40.1-0.60.10.60.1
Bone: stiffness0.40.73.2-0.80.80.10.10.1-0.80.8-0.10.0-0.80.40.11.6-1.1-1.8-0.00.50.61.20.01.3-0.11.3
Bone: tissue strength0.30.31.0-0.9-0.0-0.40.0-0.4-0.6-0.20.6-0.4-0.0-0.00.00.9-0.9-1.0-0.3-0.20.10.5-0.30.00.50.6
Bone: trabecular number1.01.52.3-1.0-1.5-1.2-1.3-1.3-1.0-1.00.9-1.21.4-1.2-1.3-1.4-1.0-0.5-1.3-1.3-1.4-1.5-1.2-1.30.9-1.4
Bone: trabecular spacing3.84.97.32.22.42.52.32.72.21.9-1.92.1-2.42.22.32.32.22.22.42.22.22.32.12.1-1.92.1
Bone: trabecular thickness0.30.30.9-0.4-0.6-0.7-0.6-1.0-0.6-0.40.3-0.50.6-0.7-0.6-0.7-0.4-0.6-0.7-0.5-0.6-0.7-0.4-0.40.2-0.7
Bone: trabecular tissue density1.01.42.4-1.5-0.8-1.3-1.2-1.2-1.5-1.01.4-1.30.8-1.2-1.2-0.2-1.5-1.4-1.3-1.1-1.1-0.8-1.3-0.71.3-0.6
Breakpoint value in progressive ratio session0.10.10.4-0.50.20.1-0.20.2-0.60.20.00.0-0.3-0.1-0.20.4-0.6-0.6-0.10.10.10.3-0.30.10.10.3
Distance traveled before self-admin0.20.20.80.70.30.20.40.30.7-0.20.10.4-0.30.40.4-0.00.80.90.40.30.40.20.30.10.10.1
Distance traveled after self-admin0.91.01.61.01.10.91.00.90.91.1-1.01.3-1.11.11.00.90.80.51.11.21.21.11.21.0-0.91.1
Delta time in closed arm before/after self-admin0.10.10.3-0.10.30.40.10.4-0.10.4-0.10.1-0.30.10.10.4-0.2-0.40.10.20.20.30.40.5-0.10.4
Delta time in open arm before/after self-admin0.20.21.10.4-0.5-0.4-0.1-0.30.4-0.60.5-0.40.5-0.2-0.1-1.00.60.6-0.1-0.3-0.4-0.70.0-0.50.4-0.7
Diff in mean of infusions in LGA sessions0.30.30.9-0.20.60.40.20.3-0.40.9-0.70.8-0.60.20.20.8-0.5-0.90.20.60.70.80.00.6-0.60.6
Extinction: sum of active levers before priming0.20.20.8-0.8-0.3-0.5-0.5-0.4-0.8-0.20.5-0.10.2-0.4-0.50.3-0.9-0.5-0.5-0.3-0.3-0.2-0.2-0.30.6-0.1
Active lever presses in extinction session 61.41.43.10.61.41.31.11.50.71.2-1.01.2-1.31.21.11.80.50.91.11.11.31.50.91.0-1.01.4
Delta distance traveled before/after self-admin0.40.50.70.70.60.80.70.90.80.8-0.80.6-0.60.70.70.50.70.70.80.70.60.60.80.6-0.70.6
Delta ambulatory time before/after self-admin0.40.40.70.50.50.70.70.80.60.8-0.80.5-0.60.70.70.50.40.30.80.70.70.70.80.7-0.70.7
Time in closed arm before self-admin0.70.83.4-1.1-0.7-1.1-1.0-1.4-1.3-0.10.1-0.30.7-1.0-1.0-0.4-1.4-1.8-1.0-0.6-0.6-0.6-0.8-0.40.1-0.5
Time in closed arm after self-admin0.10.10.4-0.00.00.0-0.1-0.2-0.20.4-0.50.1-0.0-0.1-0.1-0.1-0.2-0.70.00.10.00.00.30.6-0.40.1
Time in open arm before self-admin0.40.41.70.1-0.3-0.00.10.40.4-1.31.1-0.90.40.20.1-0.30.51.2-0.1-0.6-0.4-0.3-0.5-0.91.2-0.4
Time in open arm after self-admin0.30.31.6-0.0-0.2-0.20.20.20.2-1.31.3-0.70.20.20.2-0.20.40.8-0.1-0.5-0.3-0.0-0.5-0.91.2-0.3
Sum of active levers in priming session hrs 5-60.20.20.6-0.10.50.3-0.10.4-0.40.8-0.40.3-0.5-0.0-0.10.6-0.3-0.30.00.30.20.40.20.5-0.40.4
Time to tail flick, vehicle, before self-admin0.10.10.4-0.1-0.4-0.2-0.1-0.10.1-0.70.5-0.50.40.0-0.1-0.30.10.3-0.2-0.4-0.4-0.3-0.5-0.50.5-0.4
Time to tail flick, vehicle, after self-admin0.10.10.50.40.10.1-0.00.00.30.6-0.70.6-0.1-0.0-0.0-0.10.30.30.10.40.2-0.20.30.2-0.7-0.1
Time to tail flick, test, before self-admin1.11.02.31.50.71.00.90.81.41.1-1.41.0-0.70.80.90.11.51.01.21.00.80.41.20.8-1.40.4
Time to tail flick, test, after self-admin0.30.31.7-0.6-0.3-0.3-0.6-0.6-0.80.8-0.60.20.2-0.8-0.6-0.1-0.9-1.3-0.40.1-0.2-0.20.10.3-0.7-0.1
Delta time to tail flick, vehicle, before/after SA0.50.51.20.40.90.60.50.50.21.1-0.90.9-0.90.40.51.10.20.10.50.80.80.70.70.9-1.00.8
Delta time to tail flick, test, before/after SA1.91.74.5-1.9-1.1-1.4-1.4-1.5-2.0-0.50.8-0.91.0-1.5-1.4-0.5-2.1-2.1-1.6-1.0-1.0-0.8-1.2-0.80.8-0.7
Ambulatory time before self-admin0.10.10.90.50.1-0.00.20.10.5-0.50.40.2-0.10.20.2-0.30.70.90.20.10.1-0.10.1-0.20.4-0.2
Ambulatory time after self-admin0.10.10.40.20.30.30.30.20.30.5-0.40.5-0.30.40.30.30.1-0.00.50.50.50.40.60.5-0.30.5
Total heroin consumption0.60.82.00.21.20.90.91.10.20.7-0.40.9-1.10.90.91.30.1-0.00.70.81.11.40.50.7-0.41.3
Area under the delay curve3.84.16.4-2.2-1.9-2.3-1.8-2.0-2.0-2.42.5-2.31.9-1.9-1.8-1.0-2.1-1.4-2.0-2.2-1.9-1.5-2.4-2.12.5-1.6
Delay disc. indifference point, 0s delay0.00.10.20.00.1-0.20.4-0.20.2-0.20.1-0.1-0.10.40.30.40.10.40.1-0.00.20.30.0-0.10.10.2
Delay disc. indifference point, 16s delay4.44.56.0-2.4-2.1-2.1-2.1-1.9-2.2-2.32.4-2.42.1-2.2-2.0-1.4-2.3-1.9-2.1-2.3-2.1-1.8-2.2-1.92.4-1.7
Delay disc. indifference point, 2s delay0.50.61.1-0.9-0.6-0.9-0.6-0.9-0.9-0.91.0-0.80.6-0.6-0.7-0.1-0.9-0.6-0.7-0.8-0.6-0.4-0.7-0.71.0-0.5
Delay disc. indifference point, 24s delay0.10.10.4-0.30.2-0.10.2-0.2-0.30.2-0.20.1-0.10.10.20.6-0.4-0.60.0-0.00.30.5-0.10.3-0.20.4
Delay disc. indifference point, 4s delay4.24.48.8-2.4-1.9-2.3-1.7-1.8-2.0-2.72.9-2.61.9-1.8-1.7-0.8-2.1-1.2-2.0-2.3-1.9-1.4-2.4-2.33.0-1.5
Delay disc. indifference point, 8s delay3.53.66.4-2.1-1.7-2.0-1.7-1.7-1.9-2.42.5-2.11.7-1.7-1.7-0.9-2.0-1.4-2.0-2.1-1.8-1.4-2.4-1.82.5-1.4
Delay discount exponential model param4.04.36.52.31.92.31.82.02.12.4-2.52.3-2.02.01.91.12.11.42.12.31.91.62.42.1-2.51.7
Delay discount hyperbolic model param3.63.86.12.11.82.21.71.91.92.4-2.52.2-1.81.81.71.02.01.32.02.21.81.52.32.0-2.41.6
Fecal boli incidents, locomotor time 10.10.20.30.40.40.30.60.60.4-0.20.20.2-0.40.50.60.50.50.50.50.20.40.50.10.20.20.3
Change in fecal boli incidents, locomotor task0.30.30.8-0.3-0.7-0.5-0.5-0.5-0.2-0.40.3-0.70.7-0.4-0.5-0.9-0.2-0.3-0.5-0.5-0.6-0.7-0.5-0.70.2-0.6
Time >=10cm from walls, locomotor time 10.50.51.30.40.60.90.91.10.80.3-0.20.1-0.70.80.91.00.50.90.80.50.60.90.70.6-0.10.9
Bouts of movement, locomotor time 10.50.51.10.60.80.60.60.50.50.9-1.01.1-0.80.50.61.00.40.50.60.80.80.70.50.9-0.90.6
Total resting periods, locomotor time 10.30.31.20.10.70.50.40.50.10.8-0.60.8-0.70.40.41.1-0.10.00.40.70.70.70.30.8-0.60.7
Rest time, locomotor task time 10.60.72.00.80.80.90.81.10.90.5-0.60.7-0.80.80.81.00.81.41.00.80.80.80.70.6-0.60.7
Distance moved, locomotor task time 10.10.20.40.40.40.20.60.30.40.2-0.20.3-0.40.60.60.40.40.40.30.30.50.60.20.3-0.20.4
Vertical activity count, locomotor time 10.00.10.2-0.20.10.10.20.1-0.10.2-0.3-0.0-0.10.20.20.4-0.3-0.50.00.10.20.30.00.3-0.10.3
Time >=10cm from walls, locomotor time 20.70.71.50.20.70.90.80.80.61.1-0.90.7-0.70.90.80.80.20.00.90.91.01.11.20.9-0.91.1
Bouts of movement, locomotor time 20.60.61.4-1.1-0.3-1.1-0.4-1.1-1.1-0.81.2-0.90.4-0.6-0.40.3-1.1-1.2-0.8-0.8-0.4-0.1-0.8-0.51.1-0.0
Total resting periods, locomotor time 20.70.81.6-1.2-0.5-1.2-0.6-1.2-1.2-0.91.2-1.00.5-0.8-0.60.3-1.2-1.1-1.0-0.9-0.6-0.3-1.0-0.61.2-0.2
Rest time, locomotor task time 22.93.45.8-1.2-2.0-1.7-1.7-1.5-1.0-2.42.0-2.02.1-1.8-1.7-1.6-1.00.5-1.6-2.1-2.1-2.2-2.0-2.32.0-2.4
Distance moved, locomotor task time 23.64.25.41.92.12.02.01.91.82.3-2.12.3-2.22.12.01.51.81.12.02.32.22.12.32.2-2.12.1
Vertical activity count, locomotor time 24.34.76.11.82.22.22.31.91.82.5-2.42.4-2.22.22.31.71.70.72.22.42.42.32.42.4-2.42.3
Weight adjusted by age2.62.94.11.51.51.91.71.71.82.0-2.01.3-1.51.91.71.51.40.71.91.71.61.62.01.8-1.91.8
Seeking ratio, delayed vs. immediate footshock1.11.22.2-1.3-1.0-1.1-1.2-0.9-1.3-1.01.2-1.21.0-0.9-1.2-0.5-1.3-1.5-1.1-1.0-1.1-0.9-1.2-0.91.2-0.7
Locomotion in novel chamber0.60.83.20.1-1.2-0.4-0.4-0.30.6-1.30.8-1.21.2-0.1-0.3-1.80.50.9-0.3-0.9-0.9-1.1-0.4-1.20.8-1.2
Locomotion in novel chamber post-restriction0.10.10.5-0.10.10.10.50.40.4-0.30.5-0.1-0.20.70.50.30.10.30.30.10.20.40.40.00.50.5
Progressive ratio0.50.60.9-0.5-0.6-0.8-1.0-0.8-0.7-0.70.6-0.80.7-0.8-1.0-0.6-0.50.1-0.8-0.8-0.9-0.9-0.9-0.90.6-0.9
Food seeking constrained by brief footshock0.91.11.60.81.01.01.01.10.91.0-1.01.0-1.11.31.00.90.80.71.21.11.21.21.01.1-1.01.1
Seeking ratio, punishment vs. effort1.41.83.30.61.31.31.51.40.91.3-1.11.3-1.41.41.51.40.6-0.11.41.41.61.81.31.5-1.01.8
Run reversals in cocaine runway, females0.40.31.3-0.2-1.0-0.3-0.3-0.40.0-0.50.2-0.51.0-0.7-0.3-1.2-0.1-0.0-0.4-0.6-0.6-0.8-0.2-0.60.2-0.9
Run reversals in cocaine runway, males0.40.32.21.00.10.40.30.50.90.3-0.70.4-0.10.00.3-0.51.11.50.40.20.1-0.20.4-0.1-0.7-0.4
Latency to leave start box in cocaine runway2.12.33.01.61.51.51.71.41.61.6-1.61.6-1.51.71.71.01.61.31.61.61.61.41.51.4-1.51.5
Latency to leave start box in cocaine runway, F1.11.22.01.10.91.01.41.01.31.0-1.01.1-1.01.31.30.71.11.01.21.11.11.01.21.0-1.01.1
Latency to leave start box in cocaine runway, M1.91.82.81.51.61.31.21.21.11.6-1.61.7-1.51.21.20.91.30.91.31.51.41.21.01.3-1.61.2
Cd content in liver0.20.20.8-0.7-0.4-0.5-0.6-0.5-0.8-0.20.4-0.20.4-0.7-0.6-0.2-0.8-0.9-0.6-0.3-0.3-0.3-0.4-0.30.4-0.3
Co content in liver0.70.81.41.10.71.10.81.01.01.0-1.21.0-0.70.90.80.31.11.00.90.90.70.51.00.7-1.20.5
Cu content in liver6.47.712.9-3.2-2.8-3.0-2.4-2.6-2.7-3.33.6-3.12.8-2.5-2.4-1.9-2.9-2.5-2.7-2.9-2.5-2.1-2.9-2.83.6-2.1
Fe content in liver0.10.20.60.30.40.30.30.10.20.7-0.80.6-0.40.50.30.40.1-0.10.30.50.40.30.40.3-0.80.3
K content in liver0.20.21.6-0.30.3-0.20.4-0.3-0.30.3-0.00.2-0.30.00.40.5-0.4-1.3-0.10.20.50.70.10.4-0.00.7
Mg content in liver0.20.21.4-0.60.1-0.30.1-0.4-0.60.10.10.2-0.1-0.30.10.6-0.7-1.2-0.30.00.30.5-0.20.10.10.5
Mn content in liver0.91.02.11.40.81.11.10.81.30.8-1.01.2-0.81.01.10.11.41.01.10.91.00.71.20.7-1.00.6
Na content in liver2.72.85.4-2.0-1.5-1.8-1.6-1.8-2.0-1.41.6-1.81.5-1.9-1.6-1.0-2.0-2.3-1.8-1.7-1.6-1.2-1.7-1.41.6-1.2
Rb content in liver0.30.41.2-1.1-0.5-0.6-0.3-0.5-0.7-0.40.8-0.70.4-0.5-0.30.4-1.1-1.1-0.5-0.4-0.30.1-0.5-0.20.80.2
Se content in liver0.10.10.6-0.0-0.5-0.3-0.2-0.4-0.1-0.30.20.00.4-0.3-0.2-0.8-0.0-0.1-0.3-0.2-0.2-0.4-0.2-0.50.2-0.4
Sr content in liver1.31.12.2-0.4-1.1-0.9-1.0-0.7-0.4-1.51.2-1.21.2-0.9-1.0-1.4-0.20.4-0.9-1.2-1.3-1.4-1.0-1.41.2-1.4
Zn content in liver0.91.01.5-0.9-1.2-1.1-0.8-1.0-0.7-1.21.1-1.11.2-0.9-0.8-1.2-0.7-0.6-1.0-1.1-1.0-1.0-1.0-1.11.1-1.0