Hub : Genes

RGD1310553

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016447 0.14 0.07 6.8e-11 0.07 0.06 0.07 0.07 6.8e-08 1.0e-07 6.0e-08 6.0e-08
2 Adipose mRNA stability ENSRNOG00000016447 0.09 0.06 1.7e-08 0.02 0.04 0.03 0.03 1.7e-03 2.8e-05 1.4e-04 1.2e-04
3 BLA gene expression ENSRNOG00000016447 0.32 0.15 1.2e-07 0.14 0.15 0.13 0.13 9.6e-08 1.9e-08 2.6e-07 2.8e-07
4 Brain gene expression ENSRNOG00000016447 0.35 0.15 0.0e+00 0.14 0.18 0.18 0.18 4.2e-13 1.3e-16 8.6e-17 6.9e-17
5 Brain intron excision ratio chr9:45373526:45377235 0.03 0.02 2.6e-03 0.02 0.03 0.01 0.01 5.3e-03 2.0e-03 1.6e-02 1.4e-02
6 Brain mRNA stability ENSRNOG00000016447 0.09 0.06 2.6e-09 0.1 0.09 0.09 0.09 3.0e-09 1.0e-08 7.8e-09 7.7e-09
7 IL gene expression ENSRNOG00000016447 0.49 0.16 3.6e-06 0.19 0.19 0.18 0.23 2.4e-05 2.2e-05 3.5e-05 3.1e-06
8 LHb gene expression ENSRNOG00000016447 0.51 0.15 1.4e-06 0.19 0.19 0.14 0.14 2.8e-05 2.6e-05 4.1e-04 3.5e-04
9 Liver gene expression ENSRNOG00000016447 0.37 0.15 0.0e+00 0.18 0.2 0.19 0.2 3.1e-19 2.7e-21 1.1e-20 2.8e-21
10 Liver mRNA stability ENSRNOG00000016447 0.1 0.07 2.6e-09 0.06 0.06 0.06 0.05 6.6e-07 8.5e-07 7.0e-07 1.1e-06
11 NAcc gene expression ENSRNOG00000016447 0.27 0.1 1.3e-15 0.16 0.21 0.19 0.2 6.9e-12 7.9e-16 5.3e-14 7.6e-15
12 NAcc mRNA stability ENSRNOG00000016447 0.05 0.03 4.1e-04 0.04 0.03 0.04 0.03 1.3e-03 1.3e-03 7.6e-04 1.7e-03
13 PL gene expression ENSRNOG00000016447 0.24 0.1 0.0e+00 0.22 0.25 0.23 0.24 2.6e-16 8.6e-19 2.2e-17 3.0e-18
14 PL mRNA stability ENSRNOG00000016447 0.03 0.03 8.9e-03 0.02 0.01 0.02 -0 1.6e-02 6.3e-02 1.9e-02 6.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.34.29.82.32.5-0.40.42.72.40.01.62.43.10.51.9-1.63.0
BMI without tail0.00.10.2-0.2-0.3-0.3-0.5-0.3-0.0-0.4-0.4-0.30.1-0.30.3-0.10.1
Body weight0.00.20.50.50.30.50.20.30.30.20.40.10.70.40.60.10.7
Epididymis fat weight0.00.10.20.40.3-0.3-0.10.20.3-0.00.20.4-0.10.10.5-0.10.1
Glucose0.40.61.2-1.1-0.8-0.6-0.9-0.4-0.4-0.9-1.1-0.7-0.5-1.0-0.4-0.4-0.5
Heart weight0.50.81.90.70.8-1.0-0.51.01.4-0.80.00.91.1-0.50.9-1.10.9
Left kidney weight0.10.20.80.90.30.30.40.10.40.30.50.4-0.00.60.30.4-0.0
Right kidney weight0.71.95.51.60.22.31.7-0.4-0.41.91.6-0.1-0.22.1-0.71.9-0.3
Tail length0.72.24.2-1.9-2.0-0.3-1.2-2.0-1.6-0.8-1.8-1.9-1.8-1.1-0.30.6-1.7
Length with tail0.20.81.7-0.8-1.20.7-0.1-1.3-1.10.1-0.5-1.2-1.30.1-0.51.0-1.1
Length without tail0.81.73.21.71.51.31.41.31.01.21.81.21.31.50.20.21.4
Liver weight, left0.10.20.7-0.0-0.30.60.4-0.5-0.40.40.1-0.4-0.40.4-0.80.6-0.4
Liver weight, right0.10.20.6-0.7-0.60.2-0.0-0.6-0.80.1-0.3-0.6-0.5-0.1-0.60.4-0.5
Parametrial fat weight0.10.10.7-0.1-0.10.4-0.10.00.0-0.1-0.1-0.20.8-0.0-0.0-0.00.8
Retroperitoneal fat weight0.30.92.31.50.91.11.00.80.40.81.30.81.01.10.30.31.0
Intraocular pressure1.11.52.91.31.4-0.7-0.21.61.4-0.40.61.41.7-0.11.7-1.21.5
Extensor digitorum longus weight5.020.037.05.76.1-0.82.15.85.71.04.56.05.42.23.4-2.45.5
Soleus weight1.13.16.02.42.40.11.32.02.20.92.12.32.11.30.9-0.42.0
Tibialis anterior weight2.37.916.63.94.0-0.61.73.63.70.93.24.12.71.71.7-1.22.8
Tibia length0.30.82.2-0.5-0.91.50.4-1.1-1.10.8-0.1-1.2-0.50.6-0.61.2-0.6
Number of licking bursts0.30.40.8-0.7-0.4-0.9-0.9-0.30.1-0.8-0.8-0.2-0.4-0.80.4-0.4-0.4
Food consumed during 24 hour testing period0.30.40.90.50.6-0.4-0.30.80.7-0.50.10.60.8-0.20.9-0.80.8
Times rat made contact with spout1.72.04.2-1.7-1.3-1.6-2.0-0.7-0.4-1.9-2.0-1.0-0.9-2.00.6-1.0-0.9
Mean time between licks in bursts1.11.53.71.91.70.11.01.41.20.71.51.61.31.10.6-0.31.3
Mean num. licks in bursts0.10.10.20.10.1-0.2-0.30.30.1-0.3-0.10.10.3-0.30.2-0.40.3
Std. dev. time between licks in bursts0.50.61.10.50.8-0.7-0.31.00.9-0.50.20.81.0-0.31.1-0.91.0
Water consumed over 24 hours0.10.10.4-0.0-0.0-0.3-0.50.30.2-0.5-0.3-0.00.4-0.40.6-0.50.4
Indifference point 0 sec0.81.22.61.61.11.11.50.60.51.41.60.90.51.5-0.80.70.4
Indifference point AUC0.50.61.50.40.6-0.5-0.61.00.8-0.60.00.61.2-0.40.9-1.01.2
Indifference point function ln k0.60.82.01.11.3-0.80.31.11.3-0.00.81.40.70.30.7-0.60.8
Indifference point function log k0.60.82.01.11.3-0.80.31.11.3-0.00.81.40.70.30.7-0.60.8
Delay discounting total patch changes 0 sec0.50.82.11.51.10.71.10.80.70.91.30.90.71.1-0.50.30.6
Delay discounting total patch changes 12 sec0.70.92.80.90.01.71.2-0.3-0.51.30.9-0.2-0.31.3-1.21.1-0.4
Delay discounting total patch changes 18 sec0.60.82.00.81.0-0.3-0.11.21.2-0.20.51.01.4-0.00.4-0.91.4
Delay discounting total patch changes 24 sec0.60.81.61.20.71.31.20.40.11.11.20.50.21.2-0.70.70.2
Delay discounting total patch changes 6 sec0.30.40.80.90.60.60.80.30.20.80.90.50.20.8-0.90.40.2
Delay discounting time to switch 0 sec0.50.81.7-0.5-0.80.80.5-1.1-1.10.7-0.1-0.9-1.30.4-1.01.1-1.2
Delay discounting water rate 0 sec0.61.01.90.10.4-1.2-1.00.90.9-1.2-0.50.51.3-1.01.0-1.41.3
Delay discounting water rate 12 sec0.20.31.1-0.00.5-1.1-0.40.60.7-0.7-0.20.60.4-0.60.4-0.90.5
Delay discounting water rate 18 sec0.10.10.4-0.00.0-0.60.0-0.20.2-0.1-0.10.2-0.6-0.1-0.00.0-0.6
Delay discounting water rate 24 sec0.10.20.50.00.5-0.7-0.00.50.5-0.20.10.60.2-0.20.2-0.50.3
Delay discounting water rate 6 sec0.50.72.60.10.7-1.6-0.70.81.2-0.9-0.21.00.3-0.70.8-1.10.3
Locomotor activity0.10.10.3-0.4-0.5-0.2-0.5-0.5-0.3-0.3-0.5-0.4-0.3-0.4-0.00.1-0.3
Locomotor testing distance0.71.12.2-1.1-1.30.5-0.2-1.5-1.40.2-0.7-1.3-1.3-0.1-0.91.0-1.3
Locomotor testing rearing1.21.94.4-0.9-1.31.10.6-1.7-1.60.8-0.3-1.4-2.00.5-1.51.6-2.1
Light reinforcement 11.93.57.22.72.40.41.02.52.00.52.02.22.51.11.0-0.92.3
Light reinforcement 20.50.61.91.00.90.1-0.01.10.9-0.30.50.81.40.10.3-0.71.1
Reaction time number correct0.81.12.31.31.5-0.20.71.41.10.21.11.51.40.50.4-0.61.2
Reaction time mean minus median0.81.12.7-1.2-1.3-0.4-0.6-1.3-1.2-0.4-1.1-1.1-1.7-0.7-0.50.4-1.5
Reaction time mean minus median AUC0.60.82.4-0.9-1.1-0.3-0.5-1.2-1.0-0.3-0.9-0.9-1.5-0.5-0.30.4-1.4
Reaction time num false alarms1.31.83.31.71.7-0.20.51.71.60.21.21.71.80.51.3-0.81.8
Reaction time num false alarms AUC1.82.54.62.12.1-0.10.72.01.80.41.62.02.20.81.4-0.82.1
Reaction time trials correct on left0.81.12.31.31.5-0.20.71.41.10.21.11.51.40.50.4-0.61.2
Reaction time trials on left0.71.02.11.31.5-0.20.71.41.10.21.11.41.30.50.4-0.61.2
Reaction time mean1.82.44.2-2.0-2.0-0.3-1.2-1.9-2.0-0.8-1.8-1.9-2.0-1.1-0.50.5-1.9
Reaction time mean AUC1.41.93.3-1.8-1.8-0.4-1.2-1.6-1.7-0.9-1.7-1.6-1.7-1.2-0.30.2-1.6
Median of all reaction times1.62.24.0-2.0-2.0-0.3-1.3-1.7-1.9-0.9-1.8-1.9-1.7-1.2-0.40.3-1.7
Reaction time omissions0.60.82.5-0.7-1.1-0.0-0.4-1.2-1.1-0.2-0.8-1.0-1.6-0.3-0.40.5-1.5
Reaction time false alarm rate0.60.81.61.21.10.10.41.01.10.41.01.11.10.60.9-0.31.1
Reaction time premature initiation rate0.10.20.6-0.2-0.40.60.4-0.4-0.30.4-0.0-0.4-0.30.2-0.80.5-0.5
Reaction time premature initiations0.10.10.30.30.30.40.60.30.30.40.50.20.40.4-0.50.10.1
Std. dev. reaction times1.31.75.0-1.4-1.6-0.3-0.6-1.7-1.7-0.3-1.2-1.4-2.2-0.6-0.70.7-2.0
Reaction time trials completed0.71.02.11.31.5-0.20.71.41.10.21.11.41.30.50.4-0.61.2
Reaction time trials AUC0.71.02.01.21.4-0.20.61.41.00.11.01.41.30.40.4-0.61.1
Social response proportion0.30.30.8-0.5-0.90.1-0.4-0.5-0.6-0.3-0.8-0.9-0.4-0.5-0.10.0-0.4
Social responses0.91.12.4-1.4-1.50.0-0.8-1.2-1.3-0.6-1.4-1.5-0.9-0.9-0.30.2-1.1
Social time3.34.38.2-2.3-2.80.8-0.6-2.7-2.6-0.2-1.9-2.9-2.6-0.7-1.71.4-2.7
Conditioned locomotion0.80.92.4-1.5-1.40.2-0.9-1.0-1.2-0.6-1.3-1.6-0.3-0.9-0.40.0-0.3
Cocaine response after cond. corrected1.11.22.5-0.20.2-1.5-1.50.80.9-1.5-0.90.30.8-1.41.3-1.60.8
Cocaine response after cond. not corrected0.60.61.30.10.2-1.0-1.10.70.8-1.0-0.50.30.8-0.91.1-1.10.7
Cocaine response before conditioning0.70.92.11.10.51.21.3-0.0-0.21.41.20.3-0.11.4-0.51.1-0.1
Saline control response0.60.81.80.80.61.31.30.30.11.31.20.40.31.3-0.50.80.2
Condit. Reinf. active minus inactive responses0.60.71.4-1.1-0.9-0.9-0.9-0.6-0.6-1.0-1.2-0.7-0.8-1.10.1-0.4-0.9
Condit. Reinf. active-inactive response ratio1.41.52.9-1.7-1.6-0.4-0.9-1.3-1.3-0.7-1.5-1.5-1.5-1.1-0.70.2-1.5
Condit. Reinf. active responses0.30.41.1-0.3-0.0-1.1-0.70.30.2-1.0-0.70.10.3-0.90.7-0.90.3
Condit. Reinf. inactive responses0.91.12.01.41.4-0.20.61.31.20.11.01.41.40.50.7-0.51.4
Condit. Reinf. lever presses0.10.20.5-0.5-0.4-0.3-0.1-0.5-0.5-0.3-0.4-0.3-0.6-0.3-0.30.1-0.7
Condit. Reinf. lever reinforcers received0.40.61.6-0.20.1-1.3-0.80.50.4-1.2-0.60.30.5-1.00.9-1.10.5
Pavlov. Cond. lever latency0.20.30.60.20.4-0.3-0.40.60.7-0.30.00.40.6-0.20.8-0.60.7
Pavlov. Cond. magazine entry latency1.21.43.30.60.21.51.8-0.5-0.81.71.2-0.0-0.71.6-1.51.6-0.8
Pavlov. Cond. change in total contacts0.20.30.7-0.7-0.7-0.0-0.1-0.8-0.8-0.2-0.5-0.6-0.7-0.2-0.60.3-0.8
Pavlov. Cond. index score0.30.41.1-0.2-0.40.70.7-0.7-0.90.60.2-0.5-0.60.5-1.00.9-0.7
Pavlov. Cond. latency score0.20.30.8-0.0-0.20.60.7-0.5-0.70.60.3-0.2-0.50.5-0.90.7-0.5
Pavlov. Cond. lever contacts0.50.61.5-0.6-0.70.30.4-1.0-1.10.3-0.2-0.6-1.20.2-1.20.9-1.2
Pavlov. Cond. magazine entry number0.91.12.4-0.00.3-1.1-1.30.91.1-1.2-0.60.41.1-1.01.5-1.41.2
Pavlov. Cond. intertrial magazine entries2.12.74.91.41.8-1.2-0.42.22.2-0.80.61.92.2-0.42.0-1.82.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.0-0.20.70.8-0.5-0.70.70.4-0.3-0.40.6-1.00.9-0.5
Pavlov. Cond. response bias1.11.53.4-0.1-0.51.21.4-1.2-1.31.30.6-0.6-1.31.1-1.81.7-1.4
Conditioned reinforcement - actives0.40.41.4-0.2-0.2-1.2-1.00.00.2-1.0-0.70.1-0.1-0.90.8-0.7-0.5
Conditioned reinforcement - inactives0.20.20.80.3-0.40.20.1-0.5-0.60.1-0.1-0.4-0.90.00.10.4-0.8
Conditioned locomotion0.30.41.31.20.70.30.30.80.20.10.70.60.80.30.7-0.20.8
Intermittent access intake day 1-15 change0.20.20.90.30.0-0.00.3-0.2-0.30.30.20.1-1.00.30.30.4-0.8
Intermittent access intake escalation0.40.31.7-0.1-0.50.10.2-0.7-0.60.3-0.2-0.4-1.30.20.20.6-1.2
Intermittent access intake escalation 20.40.41.7-0.3-0.7-0.3-0.2-0.8-0.6-0.1-0.5-0.5-1.3-0.20.10.4-0.9
Intermitt. access day 1 inactive lever presses0.60.71.6-0.3-0.91.30.3-0.9-1.20.6-0.1-1.1-0.70.5-0.31.0-1.2
Intermitt. access day 15 inactive lever presses0.60.71.60.40.00.91.1-0.4-0.41.10.7-0.1-1.21.0-0.51.0-1.3
Intermitt. access escalation Index0.10.10.4-0.00.10.30.20.00.00.20.1-0.00.30.20.20.10.6
Intermittent access day 1 total infusions1.51.74.3-0.9-0.9-1.6-2.1-0.1-0.1-2.0-1.8-0.60.0-2.11.0-1.4-0.4
Intermittent access day 15 total infusions1.01.12.0-0.7-1.0-1.3-1.4-0.6-0.6-1.3-1.4-0.7-1.1-1.40.8-0.6-1.2
Intermittent access terminal intake (last 3 days)0.91.02.3-0.4-0.7-1.3-1.5-0.2-0.3-1.4-1.3-0.4-0.4-1.41.2-0.9-0.4
Intermittent access total infusions1.41.63.6-0.8-0.9-1.7-1.9-0.3-0.3-1.8-1.7-0.6-0.9-1.91.1-1.1-1.0
Intermittent access day 1 locomotion0.10.10.2-0.0-0.3-0.2-0.50.0-0.2-0.5-0.4-0.20.2-0.50.3-0.3-0.1
Intermittent access day 15 total locomotion0.10.10.50.40.1-0.4-0.10.20.2-0.2-0.00.2-0.3-0.20.7-0.2-0.3
Intermittent access total locomotion0.10.10.50.30.1-0.6-0.30.30.2-0.4-0.20.2-0.1-0.40.7-0.5-0.3
Intermittent access standard deviation1.51.63.6-1.2-1.90.0-1.4-1.4-1.5-1.1-1.7-1.8-1.2-1.10.40.2-1.2
Cocaine induced anxiety2.22.55.12.22.00.81.81.51.41.42.31.91.21.80.20.31.6
Post-drug Anxiety0.91.02.71.11.20.20.41.41.20.10.91.11.60.50.7-0.61.5
Baseline Anxiety1.92.04.5-1.9-1.4-1.1-2.1-0.6-0.6-2.0-2.1-1.3-0.1-2.10.5-1.1-0.7
Lifetime Intake1.11.32.9-0.5-0.6-1.6-1.7-0.0-0.0-1.7-1.4-0.3-0.5-1.71.2-1.2-0.7
Incentive Sensitization - Responses0.50.51.20.50.20.31.0-0.4-0.21.10.70.2-1.10.9-0.41.0-1.0
Incentive Sensitization - Breakpoint0.70.71.70.70.30.51.2-0.3-0.11.30.90.4-1.01.1-0.41.0-0.9
Progressive ratio test 1 active lever presses0.70.71.50.60.4-1.0-0.80.80.9-0.9-0.30.60.9-0.81.2-1.10.7
Progressive ratio test 1 breakpoint0.70.71.40.50.3-1.0-0.90.80.8-1.0-0.40.50.9-0.91.2-1.10.8
Progressive ratio test 1 inactive lever presses0.50.61.70.1-0.61.30.6-0.7-1.20.70.1-0.8-0.50.5-0.50.9-0.8
Progressive ratio test 2 active lever presses0.10.10.30.40.0-0.5-0.1-0.10.2-0.0-0.10.2-0.5-0.10.4-0.0-0.5
Progressive ratio test 2 breakpoint0.20.20.50.70.4-0.7-0.10.30.5-0.10.20.6-0.1-0.10.7-0.3-0.2
Progressive ratio test 2 inactive lever presses0.50.61.40.4-0.50.90.7-0.8-0.80.90.3-0.5-1.10.7-0.61.1-1.2
Total sessions with >9 infusions0.91.02.00.91.0-1.0-0.61.41.1-0.80.11.11.1-0.61.3-1.41.0
Short access day 1 total inactive lever presses0.70.81.51.10.21.11.2-0.3-0.41.21.00.1-0.71.2-0.81.1-1.1
Short access day 10 total inactive lever presses1.11.22.70.1-0.61.61.1-1.0-1.21.30.5-0.8-1.21.2-0.71.5-1.5
Short access day 1 total infusions0.20.21.31.20.4-0.20.10.40.20.00.40.50.10.10.3-0.2-0.1
Short access day 10 total infusions2.93.18.2-1.0-0.7-2.5-2.80.30.5-2.9-2.1-0.20.2-2.71.8-2.2-0.2
Short access total infusions0.70.81.90.20.0-1.2-1.30.60.5-1.4-0.80.20.5-1.31.2-1.30.3
Short access day 1 locomotion0.20.20.50.60.5-0.4-0.20.60.6-0.30.10.50.7-0.30.3-0.60.5
Short access day 10 total locomotion0.20.20.3-0.1-0.5-0.2-0.5-0.4-0.2-0.4-0.5-0.4-0.6-0.40.30.0-0.6
Short access total locomotion0.20.30.50.70.60.00.20.70.70.00.50.60.60.20.4-0.30.6
Compulsive drug intake0.20.20.8-0.5-0.2-0.40.0-0.5-0.20.1-0.1-0.0-0.7-0.1-0.40.3-0.9
One hour access (0.3 mA shock)3.54.09.2-2.0-1.9-2.1-3.0-0.9-0.7-2.8-3.0-1.5-0.9-2.91.5-1.5-1.1
One hour access (shock baseline)2.12.45.9-1.3-1.5-1.5-2.4-0.6-0.5-2.3-2.3-1.2-0.7-2.31.4-1.2-0.7
Number of responses in last shaping day0.30.40.9-0.3-0.50.60.3-0.6-0.90.6-0.1-0.6-0.80.2-0.60.6-0.8
Context. condit. distance diff. score0.91.12.0-0.8-1.11.10.4-1.4-1.40.6-0.3-1.3-1.10.4-1.11.3-1.3
Locomotion velocity, session 10.00.00.2-0.1-0.1-0.2-0.30.00.0-0.2-0.2-0.10.1-0.20.4-0.20.1
Locomotion distance, session 10.91.22.71.61.40.51.01.21.10.91.41.31.21.10.70.01.2
Locomotion velocity, session 22.52.95.02.22.2-0.30.72.22.20.31.62.22.10.81.5-1.02.2
Locomotion distance, session 21.92.77.01.82.0-0.50.32.22.0-0.11.21.92.40.41.6-1.32.6
Locomotion velocity, session 30.20.20.50.3-0.10.60.5-0.4-0.40.60.3-0.2-0.40.6-0.10.7-0.4
Locomotion distance, session 30.10.10.2-0.0-0.30.30.1-0.3-0.50.3-0.0-0.3-0.30.2-0.30.3-0.3
Stereotopy head waving bouts, day 30.20.30.7-0.8-0.7-0.2-0.4-0.6-0.6-0.4-0.7-0.6-0.6-0.5-0.20.1-0.6
Stereotopy head waving duration, day 30.20.20.5-0.7-0.4-0.6-0.5-0.3-0.2-0.6-0.7-0.3-0.4-0.70.2-0.2-0.4
Locomotion velocity, session 71.61.84.21.91.70.71.81.01.01.52.01.60.61.7-0.20.50.5
Locomotion distance, session 70.60.81.51.21.2-0.10.51.11.10.20.91.21.10.50.5-0.51.1
Stereotopy head waving bouts, day 70.10.10.1-0.4-0.40.0-0.1-0.4-0.4-0.1-0.3-0.4-0.3-0.2-0.20.1-0.3
Stereotopy head waving duration, day 70.30.40.90.1-0.20.90.7-0.5-0.60.90.4-0.3-0.50.8-0.50.9-0.5
Locomotion velocity, session 81.11.33.41.10.41.71.6-0.1-0.21.91.40.2-0.01.8-0.71.4-0.0
Locomotion distance, session 80.81.12.21.30.81.41.30.50.31.41.40.51.11.5-0.10.71.0
Degree of sensitization distance1.21.32.30.81.3-1.0-0.31.41.5-0.70.41.41.4-0.41.2-1.31.4
Degree of sensitization stereotypy0.20.20.6-0.0-0.30.80.4-0.4-0.50.60.2-0.4-0.10.5-0.50.6-0.2
Condit. Reinf. active minus inactive responses0.60.71.4-0.4-0.0-1.1-1.10.40.7-1.2-0.80.10.5-1.21.0-1.10.4
Condit. Reinf. active-inactive response ratio0.50.51.2-0.7-0.3-0.9-1.00.10.4-1.1-0.9-0.20.1-1.10.8-0.9-0.0
Condit. Reinf. active responses0.30.30.8-0.00.2-0.7-0.60.40.6-0.7-0.40.30.5-0.60.9-0.80.5
Condit. Reinf. inactive responses0.40.51.01.00.9-0.10.20.90.80.10.70.90.90.30.7-0.41.0
Incentive salience index mean0.10.10.3-0.3-0.2-0.3-0.5-0.00.3-0.5-0.5-0.20.1-0.50.4-0.3-0.0
Condit. Reinf. lever presses0.40.51.3-0.1-0.51.20.6-0.8-0.60.80.3-0.6-0.70.8-0.71.1-0.8
Time in familiar zone, hab. session 11.41.33.1-1.5-1.1-1.0-1.8-0.4-0.4-1.6-1.7-1.0-0.0-1.70.7-1.00.0
Time in novel zone, hab. session 10.30.30.8-0.4-0.5-0.0-0.0-0.7-0.50.1-0.3-0.5-0.9-0.1-0.80.4-0.9
Total zone transitions, hab. session 11.31.84.31.30.71.72.0-0.1-0.22.01.80.5-0.42.1-1.11.6-0.3
Total locomotion distance, hab. session 10.60.92.11.41.30.20.81.10.90.61.21.21.00.80.4-0.21.1
Locomotion velocity, hab. session 10.81.12.61.61.30.61.21.00.81.01.51.20.91.20.10.20.9
Time in familiar zone, hab. session 20.30.30.7-0.7-0.7-0.2-0.5-0.7-0.6-0.4-0.7-0.6-0.8-0.5-0.50.1-0.9
Time in novel zone, hab. session 20.00.00.1-0.00.00.20.10.1-0.10.10.0-0.10.20.00.20.00.3
Total zone transitions, hab. session 20.10.20.50.50.40.00.00.50.40.10.30.30.70.10.6-0.20.7
Total locomotion distance, hab. session 21.11.52.51.01.2-1.3-0.51.51.5-0.80.21.41.5-0.51.6-1.51.5
Locomotion velocity, hab. session 20.91.22.11.11.3-0.9-0.11.41.4-0.50.51.41.3-0.21.3-1.11.4
Novel to familiar place preference ratio1.61.64.0-1.3-0.8-1.6-2.0-0.00.4-2.0-1.8-0.60.3-2.00.8-1.40.3
Novelty place preference1.51.63.8-1.4-0.8-1.5-1.9-0.10.3-1.9-1.7-0.60.2-1.90.7-1.40.2
Time in novel zone, NPP test1.81.94.4-1.6-1.1-1.6-2.1-0.30.1-2.0-2.0-0.9-0.0-2.10.6-1.30.0
Total zone transitions, NPP test0.40.61.61.31.00.10.60.80.70.60.91.00.80.70.8-0.10.9
Total locomotion distance, NPP test0.70.91.81.11.2-0.70.11.21.2-0.10.71.31.10.11.2-0.81.1
Locomotion velocity, NPP test1.11.53.01.71.7-0.40.61.51.40.31.21.71.30.61.2-0.61.4
Pavlov. Cond. lever latency0.50.71.80.10.7-1.3-0.60.90.9-1.0-0.20.80.7-0.80.6-1.30.7
Pavlov. Cond. magazine entry latency0.10.10.2-0.3-0.30.30.2-0.3-0.20.2-0.0-0.3-0.20.1-0.40.3-0.3
Pavlov. Cond. change in total contacts0.10.10.2-0.1-0.0-0.1-0.40.20.4-0.4-0.3-0.10.4-0.40.4-0.40.3
Pavlov. Cond. index score0.20.30.8-0.7-0.80.4-0.2-0.8-0.6-0.0-0.5-0.9-0.5-0.1-0.30.4-0.6
Pavlov. Cond. latency score0.30.40.9-0.6-0.90.6-0.0-0.9-0.80.2-0.4-0.9-0.60.0-0.40.7-0.7
Pavlov. Cond. lever contacts0.30.30.9-0.1-0.51.00.4-0.7-0.60.60.1-0.6-0.50.5-0.50.9-0.5
Pavlov. Cond. magazine entry number0.50.61.31.11.1-0.10.41.00.80.30.91.10.80.50.6-0.41.0
Pavlov. Cond. intertrial magazine entries0.60.71.80.10.3-1.1-1.00.60.9-1.0-0.50.40.6-0.81.3-1.10.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.5-0.50.2-0.3-0.4-0.2-0.2-0.5-0.6-0.0-0.20.10.1-0.1
Pavlov. Cond. response bias0.10.20.4-0.5-0.60.4-0.1-0.6-0.30.0-0.3-0.7-0.2-0.1-0.30.4-0.4
Bone: apparent density3.15.29.5-2.3-2.81.50.0-3.1-2.90.6-1.3-2.9-2.90.0-2.62.2-2.9
Bone surface0.30.61.2-0.7-1.00.8-0.1-1.0-0.90.1-0.5-1.1-0.70.1-1.00.7-0.7
Bone volume1.52.64.7-1.7-2.01.2-0.1-2.2-2.00.3-1.0-2.1-1.9-0.0-1.91.5-1.9
Bone: connectivity density0.71.22.2-1.3-1.50.5-0.4-1.5-1.2-0.2-1.0-1.5-1.2-0.4-1.20.7-1.2
Bone: cortical apparent density3.24.19.53.12.60.92.02.12.01.72.82.51.72.20.70.21.7
Bone: cortical area0.10.10.60.40.10.80.20.10.10.40.4-0.10.40.5-0.10.30.4
Bone: cortical porosity0.60.71.3-0.9-1.00.30.0-1.2-1.10.1-0.6-1.0-1.1-0.1-0.70.7-1.1
Bone: cortical porosity0.91.01.9-0.8-1.10.80.4-1.4-1.40.5-0.4-1.1-1.40.3-1.01.1-1.4
Bone: cortical thickness0.10.20.90.50.20.90.30.10.20.60.5-0.10.60.7-0.10.40.6
Bone: cortical thickness0.00.00.3-0.1-0.10.50.1-0.1-0.20.20.1-0.30.20.2-0.10.20.2
Bone: cortical tissue density3.14.19.33.12.60.92.02.01.91.82.82.41.72.20.60.21.7
Bone: elastic displacement0.80.91.8-1.3-1.0-1.1-1.2-0.7-0.5-1.1-1.3-0.7-0.7-1.3-0.1-0.5-0.7
Bone: elastic work0.50.61.4-1.1-1.20.2-0.5-1.0-1.0-0.3-0.9-1.2-0.8-0.5-0.50.4-0.8
Bone: endosteal estimation0.10.10.2-0.4-0.5-0.0-0.3-0.3-0.5-0.4-0.5-0.5-0.1-0.40.1-0.1-0.1
Bone: endosteal perimeter0.00.10.1-0.3-0.4-0.0-0.4-0.2-0.3-0.3-0.4-0.3-0.1-0.30.3-0.1-0.1
Bone: final force0.30.62.00.70.31.40.90.1-0.11.10.90.00.41.2-0.20.80.4
Bone: final moment0.30.51.60.80.41.30.80.20.01.00.90.10.51.1-0.10.70.4
Bone: marrow area0.00.10.2-0.4-0.4-0.0-0.3-0.2-0.5-0.4-0.4-0.4-0.1-0.40.1-0.1-0.0
Bone: maximum diameter0.10.20.5-0.3-0.60.5-0.1-0.6-0.60.1-0.3-0.7-0.20.0-0.20.4-0.3
Bone: maximum force0.20.41.60.60.21.30.70.1-0.00.80.7-0.10.40.9-0.20.60.4
Bone: maximum moment0.20.31.20.60.31.10.60.20.10.70.70.00.50.8-0.10.50.5
Bone: minimum diameter0.20.51.00.90.60.70.50.60.50.50.80.51.00.70.30.11.0
Bone: periosteal estimation0.10.10.4-0.2-0.50.6-0.1-0.4-0.60.0-0.2-0.6-0.10.1-0.20.3-0.1
Bone: periosteal perimeter0.10.20.5-0.4-0.5-0.1-0.7-0.3-0.2-0.5-0.6-0.50.1-0.50.4-0.20.0
Bone: post-yield work0.60.82.30.5-0.01.51.1-0.5-0.41.30.9-0.2-0.41.3-0.81.3-0.4
Bone: stiffness0.71.13.11.00.51.81.40.2-0.11.51.40.20.41.6-0.41.10.3
Bone: tissue strength0.30.30.50.60.60.10.30.50.60.20.50.60.70.40.5-0.10.7
Bone: trabecular number2.84.37.7-1.9-2.41.80.4-2.8-2.60.9-0.9-2.6-2.60.4-2.52.2-2.5
Bone: trabecular spacing1.62.03.71.71.8-0.40.31.91.70.21.21.81.90.51.6-1.01.8
Bone: trabecular thickness3.44.27.7-2.5-2.60.7-0.5-2.7-2.5-0.1-1.7-2.6-2.7-0.6-1.91.5-2.8
Bone: trabecular tissue density0.40.51.30.60.40.71.1-0.1-0.31.10.90.3-0.51.1-0.60.9-0.5
Breakpoint value in progressive ratio session0.50.61.3-0.8-1.1-0.2-0.9-0.8-1.0-0.7-1.1-1.1-0.7-0.8-0.10.0-0.5
Distance traveled before self-admin0.20.30.6-0.4-0.70.6-0.1-0.7-0.70.1-0.3-0.8-0.30.0-0.60.5-0.2
Distance traveled after self-admin3.03.35.9-0.7-1.62.11.1-2.2-2.41.50.0-1.8-2.21.2-2.42.4-1.9
Delta time in closed arm before/after self-admin0.10.10.3-0.10.1-0.50.0-0.20.30.00.00.2-0.6-0.0-0.50.1-0.4
Delta time in open arm before/after self-admin0.20.20.8-0.9-0.60.4-0.1-0.5-0.4-0.1-0.4-0.7-0.0-0.2-0.20.2-0.0
Diff in mean of infusions in LGA sessions1.01.12.3-1.4-1.5-0.4-1.2-1.2-1.0-0.9-1.5-1.4-0.7-1.1-0.20.0-0.4
Extinction: sum of active levers before priming1.61.64.4-1.6-2.00.5-1.2-1.3-1.5-0.9-1.7-2.1-0.4-1.1-0.60.1-0.4
Active lever presses in extinction session 61.51.53.2-0.3-0.1-1.5-1.70.80.9-1.8-1.20.11.1-1.71.3-1.71.0
Delta distance traveled before/after self-admin0.80.81.50.4-0.21.01.1-0.6-0.71.20.7-0.3-1.11.1-1.21.2-1.2
Delta ambulatory time before/after self-admin0.50.61.10.5-0.10.81.0-0.5-0.70.90.6-0.1-0.80.9-0.91.0-1.1
Time in closed arm before self-admin1.21.33.2-1.5-1.2-0.9-1.6-0.4-0.5-1.6-1.8-1.1-0.0-1.70.5-1.00.0
Time in closed arm after self-admin0.40.40.9-0.5-0.90.3-0.1-0.9-0.7-0.1-0.6-0.9-0.9-0.2-0.60.5-0.8
Time in open arm before self-admin0.50.51.11.11.0-0.30.30.90.90.20.71.00.60.30.6-0.40.7
Time in open arm after self-admin0.20.20.4-0.5-0.50.40.1-0.6-0.50.3-0.1-0.5-0.40.2-0.50.6-0.4
Sum of active levers in priming session hrs 5-62.02.04.9-1.4-1.3-1.7-2.2-0.6-0.2-2.1-2.1-0.9-0.5-2.10.5-1.2-0.2
Time to tail flick, vehicle, before self-admin0.10.10.4-0.7-0.40.0-0.4-0.1-0.2-0.3-0.5-0.50.5-0.4-0.0-0.20.6
Time to tail flick, vehicle, after self-admin0.20.20.6-0.8-0.4-0.5-0.6-0.20.1-0.6-0.7-0.4-0.1-0.60.4-0.40.1
Time to tail flick, test, before self-admin1.81.83.61.11.6-1.5-0.01.61.8-0.50.71.91.5-0.21.5-1.31.5
Time to tail flick, test, after self-admin1.21.24.60.71.0-0.5-0.31.41.2-0.60.31.02.2-0.31.1-1.21.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.2-0.3-0.00.10.4-0.10.10.3-0.3-0.00.3-0.1-0.4
Delta time to tail flick, test, before/after SA0.60.51.4-1.0-1.00.5-0.8-0.5-0.8-0.6-1.0-1.20.3-0.7-0.3-0.10.2
Ambulatory time before self-admin0.10.10.2-0.3-0.40.3-0.1-0.4-0.4-0.0-0.3-0.40.2-0.1-0.20.20.3
Ambulatory time after self-admin1.11.22.50.5-0.41.61.3-0.8-1.21.40.7-0.5-1.01.3-1.51.6-0.8
Total heroin consumption1.31.53.5-1.5-1.3-0.8-1.9-0.5-0.6-1.7-1.9-1.30.1-1.80.5-1.00.0
Area under the delay curve1.81.94.5-0.8-0.1-2.1-2.00.60.8-2.1-1.40.20.4-2.01.6-1.90.3
Delay disc. indifference point, 0s delay0.70.71.71.31.10.40.90.80.80.81.21.00.61.00.40.20.7
Delay disc. indifference point, 16s delay1.81.94.3-1.7-1.1-1.6-2.0-0.5-0.3-1.9-2.0-0.8-0.6-2.10.6-1.2-0.6
Delay disc. indifference point, 2s delay0.60.71.6-0.10.1-1.2-1.20.60.6-1.3-0.70.20.7-1.21.0-1.20.3
Delay disc. indifference point, 24s delay0.20.20.5-0.5-0.2-0.7-0.6-0.1-0.1-0.6-0.5-0.0-0.3-0.60.7-0.4-0.5
Delay disc. indifference point, 4s delay0.40.40.90.50.6-0.4-0.20.80.8-0.30.10.61.0-0.21.0-0.70.8
Delay disc. indifference point, 8s delay1.11.23.2-0.8-0.1-1.8-1.60.30.7-1.6-1.20.1-0.1-1.61.1-1.4-0.1
Delay discount exponential model param1.92.04.60.90.32.12.1-0.5-0.72.11.6-0.1-0.42.1-1.61.9-0.2
Delay discount hyperbolic model param1.71.84.10.5-0.12.01.8-0.8-1.01.91.2-0.4-0.71.8-1.71.9-0.5
Fecal boli incidents, locomotor time 11.11.22.40.61.1-1.0-0.51.51.4-0.70.21.21.6-0.51.2-1.51.2
Change in fecal boli incidents, locomotor task0.30.30.8-0.4-0.70.5-0.1-0.6-0.90.0-0.3-0.7-0.2-0.0-0.80.4-0.5
Time >=10cm from walls, locomotor time 12.62.66.21.72.4-1.10.62.12.50.11.52.51.60.51.0-1.11.5
Bouts of movement, locomotor time 15.86.413.20.82.2-2.5-1.53.13.2-2.00.02.33.6-1.63.0-3.33.2
Total resting periods, locomotor time 15.35.913.51.02.3-2.2-1.13.13.1-1.60.32.43.7-1.22.7-3.03.2
Rest time, locomotor task time 11.71.94.5-1.2-0.5-1.5-2.00.40.4-2.1-1.6-0.31.3-2.01.2-1.80.5
Distance moved, locomotor task time 10.20.20.60.80.6-0.20.60.20.30.50.60.7-0.50.5-0.10.20.1
Vertical activity count, locomotor time 11.01.12.40.2-0.21.11.3-0.8-0.51.50.8-0.2-1.51.3-1.01.5-1.0
Time >=10cm from walls, locomotor time 20.10.10.2-0.2-0.1-0.4-0.40.00.4-0.4-0.3-0.10.2-0.4-0.2-0.3-0.1
Bouts of movement, locomotor time 21.31.43.21.01.2-0.6-0.31.61.4-0.60.51.21.8-0.21.6-1.21.6
Total resting periods, locomotor time 21.11.12.91.01.1-0.5-0.21.51.1-0.60.51.11.7-0.21.4-1.11.5
Rest time, locomotor task time 20.20.20.8-0.8-0.4-0.3-0.4-0.3-0.4-0.5-0.5-0.3-0.1-0.5-0.3-0.2-0.9
Distance moved, locomotor task time 20.70.81.81.01.1-0.80.01.11.3-0.00.51.20.80.00.7-0.81.2
Vertical activity count, locomotor time 20.50.50.90.90.70.60.80.50.70.90.90.60.60.80.40.20.9
Weight adjusted by age2.02.24.71.71.51.32.10.80.62.02.21.30.82.0-1.21.01.2
Seeking ratio, delayed vs. immediate footshock0.70.82.0-0.7-1.21.0-0.1-1.1-1.40.2-0.6-1.4-0.70.0-0.60.8-0.8
Locomotion in novel chamber3.84.79.52.72.7-0.50.62.92.80.11.72.63.10.62.1-1.62.9
Locomotion in novel chamber post-restriction1.61.95.41.71.60.00.51.81.40.11.11.42.30.51.3-0.92.2
Progressive ratio1.82.14.00.20.9-1.7-1.21.51.6-1.4-0.41.01.9-1.21.9-2.01.8
Food seeking constrained by brief footshock0.10.10.20.00.4-0.50.10.40.40.00.20.50.0-0.00.1-0.3-0.0
Seeking ratio, punishment vs. effort0.91.12.2-0.2-0.61.20.9-1.0-1.11.00.4-0.7-1.40.8-1.51.4-1.3
Run reversals in cocaine runway, females0.80.81.71.01.20.51.20.90.80.91.31.00.61.10.10.20.6
Run reversals in cocaine runway, males0.10.10.30.50.0-0.1-0.30.30.0-0.3-0.10.00.5-0.30.4-0.40.5
Latency to leave start box in cocaine runway1.92.13.92.01.51.31.61.30.91.51.91.21.71.70.40.31.6
Latency to leave start box in cocaine runway, F1.61.74.51.10.81.82.10.2-0.22.11.80.50.22.0-0.81.40.2
Latency to leave start box in cocaine runway, M2.72.65.42.01.8-0.60.12.12.0-0.21.01.82.30.21.8-1.42.3
Cd content in liver0.20.20.6-0.1-0.30.80.4-0.5-0.70.60.2-0.5-0.30.5-0.40.7-0.4
Co content in liver0.20.30.6-0.6-0.7-0.0-0.3-0.6-0.8-0.2-0.5-0.6-0.7-0.30.10.2-0.8
Cu content in liver0.40.41.0-0.8-0.80.1-0.2-0.8-0.9-0.3-0.6-0.8-0.9-0.4-0.20.3-1.0
Fe content in liver2.73.26.3-1.7-2.11.40.3-2.3-2.50.7-0.9-2.2-2.10.2-2.11.8-2.2
K content in liver0.80.81.51.11.10.60.90.90.90.81.21.01.01.00.20.11.1
Mg content in liver0.30.30.80.60.50.80.80.30.30.80.80.40.30.9-0.10.40.3
Mn content in liver0.50.61.30.90.90.51.10.70.60.91.10.90.50.9-0.20.30.7
Na content in liver1.11.22.5-0.1-0.51.51.1-1.0-1.01.30.5-0.6-1.21.2-1.61.5-1.0
Rb content in liver1.51.94.01.31.6-0.50.21.92.0-0.20.91.62.00.11.3-1.22.0
Se content in liver0.10.10.20.30.20.1-0.00.30.2-0.00.10.10.50.00.5-0.20.4
Sr content in liver0.60.51.8-0.20.2-1.3-0.80.40.3-1.1-0.60.40.2-1.00.8-1.10.3
Zn content in liver0.10.10.30.30.1-0.10.00.0-0.20.00.10.2-0.50.10.50.0-0.4