Vasp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS ENSRNOT00000022214 0.02 0.02 5.1e-03 0.01 0.02 0.02 0.01 3.7e-02 3.8e-03 5.4e-03 1.1e-02
2 Adipose gene expression ENSRNOG00000016367 0.5 0.19 1.3e-04 0.01 0.04 0.04 0.02 1.0e-02 1.6e-05 1.6e-05 4.2e-03
3 Adipose mRNA stability ENSRNOG00000016367 0.04 0.04 3.0e-04 0.03 0.02 0.02 0.02 8.5e-04 9.9e-04 1.9e-03 1.6e-03
4 BLA gene expression ENSRNOG00000016367 0.63 0.24 1.5e-03 0.02 0.02 0.01 0.02 3.3e-02 3.9e-02 1.1e-01 3.3e-02
5 Brain gene expression ENSRNOG00000016367 0.03 0.03 4.4e-03 0.01 0.01 0.01 0.01 1.5e-02 1.5e-02 2.5e-02 3.7e-02
6 Liver alternative TSS ENSRNOT00000022214 0.05 0.05 3.1e-04 0.02 0.02 0.03 0.02 2.7e-03 1.2e-03 6.0e-04 1.1e-03
7 Liver alternative TSS ENSRNOT00000088676 0.05 0.05 3.3e-04 0.02 0.02 0.03 0.02 5.8e-03 1.4e-03 8.1e-04 1.8e-03
8 Liver gene expression ENSRNOG00000016367 0.05 0.04 1.1e-04 0.03 0.03 0.02 0.03 3.6e-04 4.2e-04 1.1e-03 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.61.92.21.41.41.2-1.5-1.4-1.41.4-1.1
BMI without tail0.91.92.41.41.61.2-1.5-1.4-1.31.4-1.1
Body weight0.73.13.61.81.71.6-1.9-1.8-1.91.9-1.6
Epididymis fat weight0.81.92.1-1.4-1.4-1.31.31.41.4-1.41.4
Glucose0.30.40.6-0.6-0.4-0.70.60.60.7-0.70.7
Heart weight3.54.95.92.12.22.3-2.0-2.1-2.42.4-2.3
Left kidney weight8.123.327.44.74.94.7-4.5-4.7-5.25.2-4.7
Right kidney weight6.217.620.24.14.24.1-4.0-4.1-4.54.4-4.1
Tail length0.00.10.20.30.50.3-0.3-0.3-0.30.3-0.2
Length with tail0.20.70.90.80.70.8-0.8-0.8-0.90.9-0.8
Length without tail0.10.30.50.50.40.5-0.4-0.5-0.70.7-0.5
Liver weight, left9.916.018.53.93.73.9-4.0-3.9-4.34.3-3.9
Liver weight, right2.54.15.41.81.82.1-1.7-1.9-2.32.3-2.1
Parametrial fat weight0.00.10.20.3-0.20.3-0.4-0.3-0.10.2-0.4
Retroperitoneal fat weight0.00.10.2-0.3-0.4-0.30.20.30.5-0.40.3
Intraocular pressure0.00.00.0-0.10.0-0.10.00.1-0.00.00.1
Extensor digitorum longus weight1.45.76.92.51.62.2-2.5-2.5-2.62.6-2.4
Soleus weight0.10.20.30.50.40.4-0.4-0.5-0.60.6-0.5
Tibialis anterior weight3.311.413.53.42.93.3-3.3-3.4-3.73.6-3.4
Tibia length0.41.13.90.82.00.8-0.7-0.8-1.01.0-0.6
Number of licking bursts2.53.04.21.91.91.4-2.0-1.8-1.51.6-1.4
Food consumed during 24 hour testing period5.56.67.4-2.7-2.7-2.42.72.62.6-2.62.4
Times rat made contact with spout0.00.00.0-0.1-0.20.20.20.1-0.20.2-0.2
Mean time between licks in bursts0.10.10.1-0.2-0.3-0.30.20.30.3-0.30.3
Mean num. licks in bursts2.42.94.5-1.9-2.0-1.32.11.81.4-1.41.3
Std. dev. time between licks in bursts0.00.00.10.0-0.10.20.0-0.0-0.30.2-0.2
Water consumed over 24 hours0.10.20.4-0.5-0.6-0.20.60.40.2-0.20.2
Indifference point 0 sec0.40.60.80.80.70.8-0.9-0.8-0.80.8-0.8
Indifference point AUC3.23.84.82.02.21.8-2.0-1.9-1.91.9-1.8
Indifference point function ln k0.91.32.8-1.1-1.7-1.01.11.11.0-1.00.9
Indifference point function log k0.91.32.8-1.1-1.7-1.01.11.11.0-1.00.9
Delay discounting total patch changes 0 sec0.61.01.21.00.61.0-1.1-1.0-1.11.1-1.1
Delay discounting total patch changes 12 sec1.21.52.11.31.41.1-1.4-1.3-1.21.2-1.1
Delay discounting total patch changes 18 sec2.12.73.21.61.31.6-1.7-1.6-1.81.8-1.7
Delay discounting total patch changes 24 sec0.20.30.50.5-0.00.5-0.7-0.5-0.60.6-0.6
Delay discounting total patch changes 6 sec2.53.84.21.92.11.9-2.0-1.9-2.02.0-1.9
Delay discounting time to switch 0 sec4.26.48.0-2.4-2.5-2.42.32.42.8-2.82.5
Delay discounting water rate 0 sec4.57.18.32.62.62.6-2.5-2.6-2.92.8-2.7
Delay discounting water rate 12 sec0.30.50.80.60.50.7-0.4-0.6-0.90.8-0.8
Delay discounting water rate 18 sec0.10.20.30.40.10.5-0.3-0.4-0.60.5-0.6
Delay discounting water rate 24 sec0.70.91.20.91.01.0-0.9-0.9-1.11.1-1.0
Delay discounting water rate 6 sec0.81.21.60.90.81.2-0.9-1.0-1.31.2-1.2
Locomotor activity2.23.45.41.92.31.7-1.8-1.8-1.81.8-1.7
Locomotor testing distance0.81.21.91.21.41.0-1.0-1.1-1.11.1-1.0
Locomotor testing rearing5.38.39.02.93.02.8-2.9-2.9-3.03.0-2.7
Light reinforcement 10.10.20.30.20.10.6-0.2-0.3-0.50.5-0.6
Light reinforcement 20.10.10.20.20.30.40.0-0.2-0.30.2-0.5
Reaction time number correct5.57.88.92.82.72.7-2.8-2.8-3.03.0-2.7
Reaction time mean minus median0.10.10.2-0.4-0.2-0.20.50.30.2-0.20.2
Reaction time mean minus median AUC0.20.20.30.40.50.5-0.2-0.4-0.60.5-0.5
Reaction time num false alarms4.36.07.02.42.12.5-2.5-2.4-2.62.6-2.5
Reaction time num false alarms AUC3.44.85.32.21.82.2-2.3-2.2-2.32.3-2.2
Reaction time trials correct on left5.57.88.92.82.72.7-2.8-2.8-3.03.0-2.7
Reaction time trials on left5.57.88.92.82.72.7-2.8-2.8-3.03.0-2.7
Reaction time mean1.21.62.5-1.4-1.1-1.01.61.31.2-1.21.1
Reaction time mean AUC0.91.31.9-1.2-1.2-0.91.41.21.1-1.10.8
Median of all reaction times1.62.23.1-1.6-1.4-1.21.81.61.5-1.51.2
Reaction time omissions0.10.10.20.20.20.4-0.1-0.2-0.40.4-0.4
Reaction time false alarm rate0.10.10.20.30.30.4-0.4-0.3-0.30.3-0.4
Reaction time premature initiation rate0.40.60.8-0.8-0.8-0.60.90.80.7-0.70.7
Reaction time premature initiations0.30.40.70.60.30.7-0.6-0.6-0.80.8-0.7
Std. dev. reaction times0.20.30.5-0.6-0.5-0.40.70.50.5-0.50.4
Reaction time trials completed5.57.88.92.82.72.7-2.8-2.8-3.03.0-2.7
Reaction time trials AUC6.79.510.93.13.03.0-3.1-3.1-3.33.3-3.0
Social response proportion1.41.52.11.10.91.4-1.0-1.1-1.41.4-1.4
Social responses0.81.01.31.00.81.1-1.0-1.0-1.11.1-1.1
Social time3.85.05.4-2.2-2.2-2.22.22.22.3-2.32.2
Conditioned locomotion0.00.10.1-0.2-0.0-0.20.30.20.2-0.20.2
Cocaine response after cond. corrected0.70.81.00.90.60.9-0.8-0.9-1.01.0-0.9
Cocaine response after cond. not corrected1.82.02.51.31.11.5-1.3-1.4-1.61.6-1.5
Cocaine response before conditioning1.72.12.71.41.71.4-1.4-1.4-1.51.4-1.4
Saline control response1.72.22.41.51.51.4-1.5-1.5-1.61.5-1.4
Condit. Reinf. active minus inactive responses0.10.20.40.30.60.5-0.2-0.3-0.50.5-0.4
Condit. Reinf. active-inactive response ratio0.70.81.10.70.81.0-0.6-0.8-1.01.0-1.0
Condit. Reinf. active responses0.10.10.2-0.30.1-0.20.40.30.3-0.30.3
Condit. Reinf. inactive responses0.81.01.3-1.0-0.7-1.01.01.01.1-1.11.1
Condit. Reinf. lever presses0.40.61.20.61.10.7-0.5-0.6-0.80.8-0.6
Condit. Reinf. lever reinforcers received0.10.10.2-0.4-0.0-0.30.40.40.3-0.30.4
Pavlov. Cond. lever latency0.00.00.1-0.0-0.30.1-0.00.0-0.00.0-0.1
Pavlov. Cond. magazine entry latency0.10.10.30.10.10.50.0-0.2-0.60.5-0.4
Pavlov. Cond. change in total contacts0.20.20.4-0.5-0.5-0.40.60.50.4-0.40.4
Pavlov. Cond. index score0.00.00.1-0.20.00.00.30.1-0.10.10.0
Pavlov. Cond. latency score0.00.00.1-0.3-0.2-0.10.40.20.0-0.00.1
Pavlov. Cond. lever contacts0.20.30.50.40.70.5-0.4-0.5-0.60.6-0.4
Pavlov. Cond. magazine entry number0.30.40.80.80.70.5-0.9-0.7-0.50.5-0.6
Pavlov. Cond. intertrial magazine entries0.00.00.00.10.00.0-0.2-0.1-0.00.0-0.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.00.20.30.1-0.1-0.30.3-0.2
Pavlov. Cond. response bias0.00.00.10.10.30.2-0.0-0.1-0.30.3-0.2
Conditioned reinforcement - actives0.90.91.00.91.01.0-0.9-1.0-0.90.9-1.0
Conditioned reinforcement - inactives0.60.70.90.90.80.8-1.0-0.9-0.70.8-0.8
Conditioned locomotion3.03.63.81.91.91.9-1.9-1.9-1.91.9-1.9
Intermittent access intake day 1-15 change0.30.30.50.50.70.5-0.4-0.5-0.70.6-0.5
Intermittent access intake escalation0.30.30.50.50.70.4-0.4-0.5-0.70.7-0.4
Intermittent access intake escalation 20.50.50.90.60.80.6-0.5-0.6-1.00.9-0.6
Intermitt. access day 1 inactive lever presses0.10.20.20.50.50.4-0.4-0.5-0.00.1-0.4
Intermitt. access day 15 inactive lever presses0.30.30.40.60.60.6-0.7-0.6-0.20.3-0.6
Intermitt. access escalation Index0.20.20.5-0.4-0.7-0.40.40.50.4-0.40.4
Intermittent access day 1 total infusions0.91.01.11.01.11.0-1.0-1.0-0.80.9-1.0
Intermittent access day 15 total infusions0.60.71.00.81.00.8-0.8-0.8-0.80.8-0.8
Intermittent access terminal intake (last 3 days)1.11.21.61.11.31.1-1.0-1.1-1.01.0-1.1
Intermittent access total infusions2.02.22.71.51.61.5-1.5-1.5-1.31.4-1.5
Intermittent access day 1 locomotion0.20.20.30.50.60.5-0.4-0.5-0.40.4-0.5
Intermittent access day 15 total locomotion0.50.60.80.70.90.7-0.7-0.7-0.80.8-0.7
Intermittent access total locomotion1.92.22.71.51.61.5-1.4-1.5-1.41.4-1.5
Intermittent access standard deviation0.50.50.60.70.80.7-0.7-0.7-0.70.7-0.7
Cocaine induced anxiety1.31.52.3-1.1-1.3-1.11.01.11.5-1.41.1
Post-drug Anxiety0.30.30.6-0.4-0.7-0.50.20.40.8-0.70.5
Baseline Anxiety0.60.60.70.80.70.7-0.8-0.8-0.80.8-0.7
Lifetime Intake1.61.72.01.41.41.3-1.4-1.4-1.21.2-1.3
Incentive Sensitization - Responses0.10.10.20.40.10.2-0.5-0.3-0.20.2-0.2
Incentive Sensitization - Breakpoint0.10.10.20.30.00.2-0.4-0.3-0.10.1-0.2
Progressive ratio test 1 active lever presses0.91.01.21.01.11.0-1.0-1.0-0.90.9-1.0
Progressive ratio test 1 breakpoint0.60.70.90.81.00.8-0.8-0.8-0.70.8-0.8
Progressive ratio test 1 inactive lever presses0.50.50.90.80.90.8-0.7-0.8-0.50.6-0.8
Progressive ratio test 2 active lever presses0.20.20.40.60.40.4-0.6-0.5-0.30.4-0.4
Progressive ratio test 2 breakpoint0.10.20.30.50.30.4-0.5-0.5-0.20.3-0.4
Progressive ratio test 2 inactive lever presses0.00.00.1-0.0-0.1-0.1-0.00.00.3-0.30.1
Total sessions with >9 infusions3.03.33.61.91.91.8-1.9-1.8-1.71.7-1.8
Short access day 1 total inactive lever presses1.41.51.71.31.21.2-1.3-1.3-1.21.2-1.2
Short access day 10 total inactive lever presses0.60.70.7-0.8-0.8-0.80.80.80.9-0.80.8
Short access day 1 total infusions1.01.01.21.00.91.0-1.1-1.0-1.11.1-1.0
Short access day 10 total infusions2.22.52.71.61.71.6-1.6-1.6-1.31.4-1.6
Short access total infusions0.40.50.70.70.70.7-0.8-0.7-0.50.6-0.7
Short access day 1 locomotion1.11.21.31.01.11.0-1.1-1.0-1.11.1-1.0
Short access day 10 total locomotion0.00.00.1-0.00.20.00.10.0-0.30.2-0.0
Short access total locomotion0.10.10.20.30.50.4-0.3-0.3-0.30.3-0.4
Compulsive drug intake0.00.00.10.00.30.20.2-0.10.3-0.2-0.2
One hour access (0.3 mA shock)0.00.00.1-0.20.1-0.20.30.20.1-0.10.2
One hour access (shock baseline)1.31.61.91.21.31.2-1.2-1.2-1.41.4-1.2
Number of responses in last shaping day3.43.44.31.81.81.7-1.8-1.8-2.12.0-1.7
Context. condit. distance diff. score0.10.20.20.40.10.4-0.5-0.4-0.40.4-0.4
Locomotion velocity, session 10.10.10.1-0.1-0.0-0.30.10.10.4-0.30.3
Locomotion distance, session 10.10.10.10.20.30.4-0.0-0.2-0.40.3-0.4
Locomotion velocity, session 21.21.41.81.31.31.0-1.4-1.2-1.01.1-1.0
Locomotion distance, session 20.40.50.80.60.60.8-0.5-0.6-0.90.8-0.8
Locomotion velocity, session 30.20.30.30.50.50.5-0.5-0.5-0.60.6-0.5
Locomotion distance, session 30.80.91.0-1.0-0.9-0.81.01.00.9-0.90.8
Stereotopy head waving bouts, day 30.81.01.61.11.10.8-1.3-1.1-0.80.8-0.8
Stereotopy head waving duration, day 30.81.01.31.11.00.9-1.1-1.0-1.01.0-0.9
Locomotion velocity, session 70.10.10.3-0.5-0.5-0.20.60.40.2-0.20.2
Locomotion distance, session 70.00.00.10.10.00.20.0-0.1-0.30.2-0.2
Stereotopy head waving bouts, day 70.70.71.00.90.90.8-1.0-0.9-0.80.8-0.8
Stereotopy head waving duration, day 70.60.81.21.00.90.8-1.1-0.9-0.80.8-0.8
Locomotion velocity, session 80.00.00.0-0.0-0.1-0.1-0.10.00.2-0.20.1
Locomotion distance, session 80.10.10.20.1-0.10.4-0.1-0.2-0.40.4-0.4
Degree of sensitization distance0.50.60.70.70.60.7-0.7-0.7-0.80.8-0.7
Degree of sensitization stereotypy1.01.11.31.11.11.0-1.1-1.1-1.01.0-1.0
Condit. Reinf. active minus inactive responses0.50.50.70.60.70.8-0.6-0.6-0.90.8-0.7
Condit. Reinf. active-inactive response ratio0.40.40.70.50.50.8-0.5-0.5-0.90.8-0.7
Condit. Reinf. active responses0.40.40.70.50.70.8-0.4-0.5-0.80.8-0.7
Condit. Reinf. inactive responses0.00.00.1-0.10.00.20.30.1-0.20.2-0.2
Incentive salience index mean0.30.30.40.50.60.6-0.4-0.5-0.70.6-0.6
Condit. Reinf. lever presses0.00.00.00.00.10.00.0-0.0-0.00.0-0.0
Time in familiar zone, hab. session 10.20.10.20.40.30.3-0.5-0.4-0.40.4-0.3
Time in novel zone, hab. session 10.50.50.50.70.70.7-0.7-0.7-0.70.7-0.7
Total zone transitions, hab. session 10.20.30.50.50.40.7-0.4-0.5-0.70.7-0.7
Total locomotion distance, hab. session 10.40.60.8-0.8-0.9-0.80.70.80.8-0.80.8
Locomotion velocity, hab. session 11.31.82.0-1.3-1.4-1.31.31.31.4-1.41.3
Time in familiar zone, hab. session 20.20.20.40.50.50.3-0.6-0.4-0.20.2-0.3
Time in novel zone, hab. session 20.00.00.1-0.2-0.2-0.10.30.1-0.0-0.00.1
Total zone transitions, hab. session 20.50.60.90.81.00.7-0.9-0.8-0.70.7-0.7
Total locomotion distance, hab. session 20.70.91.2-0.9-1.0-1.00.80.91.1-1.01.0
Locomotion velocity, hab. session 20.40.60.7-0.7-0.8-0.80.60.70.8-0.80.8
Novel to familiar place preference ratio1.21.32.20.90.71.3-0.7-0.9-1.51.4-1.3
Novelty place preference1.11.11.90.80.71.2-0.6-0.9-1.41.3-1.2
Time in novel zone, NPP test1.31.32.20.90.81.3-0.8-1.0-1.51.4-1.3
Total zone transitions, NPP test0.10.20.50.50.70.4-0.5-0.5-0.40.4-0.4
Total locomotion distance, NPP test0.10.10.20.40.40.4-0.4-0.4-0.40.4-0.4
Locomotion velocity, NPP test0.10.10.10.30.40.4-0.3-0.3-0.40.4-0.4
Pavlov. Cond. lever latency0.30.40.5-0.6-0.6-0.60.60.60.7-0.70.6
Pavlov. Cond. magazine entry latency0.10.10.20.30.20.3-0.3-0.3-0.40.4-0.3
Pavlov. Cond. change in total contacts0.60.70.9-0.9-0.7-0.71.00.90.8-0.80.8
Pavlov. Cond. index score0.20.30.30.50.50.5-0.5-0.5-0.60.6-0.5
Pavlov. Cond. latency score0.00.00.00.20.20.2-0.2-0.2-0.20.2-0.1
Pavlov. Cond. lever contacts0.50.60.70.70.70.7-0.7-0.8-0.80.8-0.7
Pavlov. Cond. magazine entry number0.00.00.0-0.10.2-0.00.10.10.1-0.10.0
Pavlov. Cond. intertrial magazine entries0.10.10.20.20.30.4-0.2-0.3-0.40.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.50.60.60.6-0.6-0.6-0.70.7-0.6
Pavlov. Cond. response bias1.31.62.01.21.01.3-1.2-1.2-1.41.4-1.2
Bone: apparent density0.00.10.3-0.3-0.6-0.00.30.3-0.0-0.0-0.0
Bone surface0.10.20.40.30.30.5-0.2-0.3-0.60.6-0.5
Bone volume0.10.10.20.20.00.4-0.2-0.2-0.50.4-0.4
Bone: connectivity density0.10.10.4-0.4-0.6-0.10.50.40.1-0.10.1
Bone: cortical apparent density0.00.00.0-0.1-0.1-0.00.00.10.1-0.10.1
Bone: cortical area1.11.72.21.31.51.2-1.3-1.3-1.31.3-1.2
Bone: cortical porosity0.20.20.4-0.3-0.4-0.40.20.40.6-0.60.4
Bone: cortical porosity0.00.00.00.0-0.1-0.0-0.10.00.2-0.2-0.0
Bone: cortical thickness0.30.50.70.70.80.7-0.7-0.7-0.80.7-0.7
Bone: cortical thickness1.31.51.81.21.31.2-1.2-1.2-1.31.3-1.2
Bone: cortical tissue density0.00.00.0-0.2-0.2-0.10.10.20.2-0.20.2
Bone: elastic displacement1.61.83.8-1.2-2.0-1.21.11.21.4-1.31.2
Bone: elastic work0.00.00.00.0-0.10.2-0.0-0.0-0.10.1-0.2
Bone: endosteal estimation0.00.10.1-0.3-0.2-0.30.30.20.2-0.20.3
Bone: endosteal perimeter0.00.00.20.00.40.10.0-0.0-0.00.00.0
Bone: final force0.30.50.50.70.70.7-0.7-0.7-0.70.7-0.7
Bone: final moment0.40.70.80.80.90.8-0.9-0.8-0.90.9-0.8
Bone: marrow area0.00.00.1-0.2-0.2-0.30.30.20.2-0.20.2
Bone: maximum diameter1.93.44.61.92.11.7-1.8-1.9-1.91.9-1.6
Bone: maximum force0.20.30.40.50.70.6-0.5-0.5-0.60.6-0.6
Bone: maximum moment0.30.50.60.60.80.6-0.7-0.6-0.70.7-0.7
Bone: minimum diameter0.20.30.40.50.30.5-0.6-0.5-0.60.5-0.6
Bone: periosteal estimation0.10.30.50.50.70.4-0.5-0.5-0.60.6-0.4
Bone: periosteal perimeter0.20.30.70.50.80.5-0.4-0.5-0.50.5-0.4
Bone: post-yield work0.30.50.7-0.8-0.5-0.50.80.80.6-0.60.6
Bone: stiffness0.81.21.41.11.21.0-1.1-1.1-1.11.1-1.1
Bone: tissue strength0.40.40.6-0.7-0.8-0.50.70.60.6-0.50.5
Bone: trabecular number0.20.30.7-0.6-0.8-0.30.60.60.3-0.40.3
Bone: trabecular spacing0.10.20.40.60.10.2-0.6-0.6-0.40.4-0.2
Bone: trabecular thickness1.21.41.71.11.31.2-1.0-1.1-1.31.3-1.2
Bone: trabecular tissue density0.81.12.21.01.50.9-1.0-1.0-1.01.0-0.8
Breakpoint value in progressive ratio session6.06.77.4-2.5-2.7-2.62.42.52.7-2.72.6
Distance traveled before self-admin0.30.30.30.50.60.6-0.5-0.5-0.60.6-0.6
Distance traveled after self-admin0.60.70.7-0.8-0.8-0.80.80.80.9-0.90.8
Delta time in closed arm before/after self-admin0.00.00.00.00.10.10.0-0.0-0.10.1-0.1
Delta time in open arm before/after self-admin0.20.10.2-0.4-0.2-0.40.50.40.4-0.40.4
Diff in mean of infusions in LGA sessions4.24.75.4-2.1-2.3-2.12.02.12.3-2.32.1
Extinction: sum of active levers before priming2.02.12.4-1.4-1.6-1.41.31.41.5-1.51.4
Active lever presses in extinction session 60.00.00.00.1-0.00.0-0.1-0.1-0.10.1-0.0
Delta distance traveled before/after self-admin3.53.74.2-1.9-1.9-1.91.91.92.0-2.01.9
Delta ambulatory time before/after self-admin1.21.31.5-1.1-1.1-1.11.11.11.2-1.21.1
Time in closed arm before self-admin1.61.92.61.31.61.4-1.1-1.3-1.41.4-1.4
Time in closed arm after self-admin0.00.00.00.00.20.1-0.0-0.1-0.10.1-0.1
Time in open arm before self-admin0.91.01.7-0.9-1.3-1.00.70.91.1-1.01.0
Time in open arm after self-admin0.91.01.1-0.9-1.1-1.00.90.91.1-1.01.0
Sum of active levers in priming session hrs 5-61.41.41.6-1.1-1.2-1.21.11.11.2-1.21.2
Time to tail flick, vehicle, before self-admin3.53.53.71.91.91.8-1.9-1.8-1.91.9-1.8
Time to tail flick, vehicle, after self-admin0.30.30.30.50.50.5-0.5-0.5-0.50.5-0.5
Time to tail flick, test, before self-admin0.40.40.7-0.5-0.8-0.60.40.50.6-0.60.6
Time to tail flick, test, after self-admin0.10.10.10.30.30.3-0.3-0.3-0.30.3-0.3
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.2-0.3-0.20.20.20.2-0.20.2
Delta time to tail flick, test, before/after SA2.42.13.11.41.81.4-1.3-1.4-1.51.5-1.4
Ambulatory time before self-admin0.00.00.00.10.20.1-0.1-0.1-0.10.1-0.1
Ambulatory time after self-admin1.01.11.2-1.0-1.1-1.01.01.01.1-1.11.0
Total heroin consumption0.50.60.7-0.8-0.7-0.80.80.80.9-0.80.8
Area under the delay curve2.32.53.1-1.5-1.2-1.71.41.51.8-1.71.7
Delay disc. indifference point, 0s delay1.21.31.8-1.1-1.0-1.21.01.11.3-1.31.2
Delay disc. indifference point, 16s delay1.31.31.5-1.1-1.1-1.21.11.11.2-1.21.2
Delay disc. indifference point, 2s delay4.34.86.3-2.0-1.7-2.41.92.12.5-2.52.4
Delay disc. indifference point, 24s delay0.10.10.20.20.30.3-0.2-0.3-0.40.4-0.3
Delay disc. indifference point, 4s delay0.00.00.10.00.3-0.1-0.0-0.00.1-0.10.1
Delay disc. indifference point, 8s delay2.02.12.4-1.4-1.2-1.51.41.41.6-1.61.5
Delay discount exponential model param1.71.82.31.31.01.5-1.2-1.3-1.51.5-1.5
Delay discount hyperbolic model param1.41.52.01.10.81.4-1.1-1.2-1.41.4-1.4
Fecal boli incidents, locomotor time 10.00.00.00.00.0-0.1-0.0-0.00.1-0.10.1
Change in fecal boli incidents, locomotor task1.01.01.1-0.9-0.9-1.00.91.01.1-1.01.0
Time >=10cm from walls, locomotor time 10.00.00.2-0.2-0.40.10.20.2-0.00.0-0.1
Bouts of movement, locomotor time 12.42.63.0-1.6-1.7-1.51.71.61.6-1.61.5
Total resting periods, locomotor time 12.93.23.4-1.8-1.9-1.71.81.81.8-1.81.7
Rest time, locomotor task time 10.00.00.1-0.2-0.3-0.10.30.20.2-0.20.1
Distance moved, locomotor task time 10.10.10.30.40.50.2-0.4-0.4-0.30.3-0.2
Vertical activity count, locomotor time 10.20.20.2-0.3-0.2-0.50.30.40.5-0.50.5
Time >=10cm from walls, locomotor time 20.20.20.3-0.4-0.4-0.50.30.40.6-0.60.5
Bouts of movement, locomotor time 25.55.96.5-2.5-2.5-2.32.52.52.5-2.52.3
Total resting periods, locomotor time 24.85.25.8-2.3-2.3-2.12.42.32.3-2.32.1
Rest time, locomotor task time 20.00.00.1-0.1-0.40.10.20.1-0.10.1-0.1
Distance moved, locomotor task time 20.40.40.90.71.00.5-0.8-0.7-0.60.6-0.5
Vertical activity count, locomotor time 20.30.30.5-0.5-0.2-0.70.40.50.7-0.70.7
Weight adjusted by age0.00.00.1-0.1-0.2-0.30.10.10.3-0.20.3
Seeking ratio, delayed vs. immediate footshock1.61.82.5-1.4-1.6-1.31.21.41.4-1.41.3
Locomotion in novel chamber0.40.50.6-0.7-0.4-0.70.70.70.8-0.70.7
Locomotion in novel chamber post-restriction1.41.61.9-1.3-1.4-1.21.21.31.4-1.31.2
Progressive ratio0.60.71.3-0.8-1.2-0.80.50.81.0-0.90.8
Food seeking constrained by brief footshock5.66.87.5-2.6-2.4-2.52.72.62.7-2.72.5
Seeking ratio, punishment vs. effort0.91.11.9-1.1-0.7-1.01.41.11.0-1.01.0
Run reversals in cocaine runway, females0.40.40.4-0.6-0.5-0.60.60.60.7-0.60.6
Run reversals in cocaine runway, males0.90.81.00.90.90.9-0.9-0.9-1.01.0-0.9
Latency to leave start box in cocaine runway0.10.10.20.10.10.4-0.1-0.2-0.40.4-0.4
Latency to leave start box in cocaine runway, F0.50.60.70.70.70.8-0.8-0.7-0.80.8-0.8
Latency to leave start box in cocaine runway, M0.10.10.10.0-0.00.30.1-0.1-0.40.3-0.3
Cd content in liver0.00.00.1-0.0-0.2-0.00.00.0-0.00.00.0
Co content in liver2.42.83.4-1.6-1.8-1.71.61.61.8-1.71.6
Cu content in liver0.10.10.40.3-0.6-0.0-0.4-0.3-0.10.1-0.2
Fe content in liver1.21.43.11.21.80.9-1.2-1.2-1.01.1-0.7
K content in liver0.10.10.30.40.1-0.1-0.5-0.4-0.10.20.0
Mg content in liver0.10.10.30.30.5-0.1-0.4-0.3-0.10.10.1
Mn content in liver0.91.01.11.10.80.9-1.1-1.1-1.01.0-1.0
Na content in liver0.20.20.5-0.2-0.7-0.40.10.20.5-0.50.3
Rb content in liver0.00.10.2-0.0-0.5-0.30.0-0.0-0.10.10.3
Se content in liver1.41.62.71.41.71.1-1.5-1.3-1.11.1-1.1
Sr content in liver0.20.20.30.40.60.5-0.5-0.4-0.20.2-0.4
Zn content in liver0.10.10.20.3-0.40.4-0.3-0.3-0.30.3-0.4