Hub : Genes

Cnpy3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016315 0.17 0.07 0.0e+00 0.17 0.2 0.19 0.19 6.8e-19 2.3e-21 7.9e-21 7.3e-21
2 BLA gene expression ENSRNOG00000016315 0.42 0.14 5.6e-17 0.29 0.32 0.32 0.33 4.0e-16 5.5e-18 5.7e-18 2.1e-18
3 Brain gene expression ENSRNOG00000016315 0.35 0.12 0.0e+00 0.29 0.29 0.3 0.3 4.0e-27 1.5e-27 1.1e-28 5.4e-28
4 Brain intron excision ratio chr9:14237487:14242286 0.02 0.02 8.2e-03 0.02 0.02 0.02 0.02 3.8e-03 9.1e-03 7.4e-03 9.5e-03
5 Brain mRNA stability ENSRNOG00000016315 0.07 0.05 1.0e-04 0.04 0.03 0.04 0.04 1.0e-04 8.6e-04 1.1e-04 2.9e-04
6 IL gene expression ENSRNOG00000016315 0.3 0.16 1.8e-04 0.23 0.16 0.19 0.24 2.7e-06 1.2e-04 2.1e-05 1.7e-06
7 LHb gene expression ENSRNOG00000016315 0.14 0.1 7.5e-03 0.15 0.04 0.06 0.09 2.0e-04 3.3e-02 1.6e-02 3.3e-03
8 Liver gene expression ENSRNOG00000016315 0.19 0.08 0.0e+00 0.12 0.2 0.2 0.19 2.1e-13 2.3e-21 3.7e-21 5.4e-21
9 Liver intron excision ratio chr9:14237487:14242286 0.03 0.02 4.6e-03 0.02 0.01 0 0.01 4.1e-03 1.5e-02 1.7e-01 1.8e-02
10 Liver intron excision ratio chr9:14242382:14245813 0.03 0.03 2.0e-03 0.02 0.01 0.01 0.01 2.5e-03 7.3e-03 3.9e-02 1.3e-02
11 Liver mRNA stability ENSRNOG00000016315 0.04 0.03 6.1e-05 0.04 0.03 0.03 0.03 4.6e-05 1.3e-04 1.0e-04 1.5e-04
12 NAcc gene expression ENSRNOG00000016315 0.21 0.13 5.7e-08 0.1 0.1 0.1 0.1 1.0e-07 3.8e-08 1.4e-07 8.9e-08
13 PL gene expression ENSRNOG00000016315 0.75 0.02 5.0e-16 0.2 0.22 0.22 0.2 2.3e-15 9.8e-17 9.7e-17 5.6e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail2.47.714.6-2.8-1.7-0.93.8-3.3-0.4-3.7-2.43.7-3.7-3.8-1.2-0.6
BMI without tail7.415.527.6-4.3-3.0-2.05.2-4.0-1.2-5.3-3.85.1-5.1-5.1-2.2-1.2
Body weight2.08.413.7-3.4-2.5-1.93.6-2.2-1.2-3.7-3.23.6-3.6-3.6-2.1-1.2
Epididymis fat weight2.35.37.9-2.7-2.6-2.42.2-0.2-2.0-2.3-2.82.3-2.3-2.2-2.5-2.3
Glucose3.96.08.4-2.8-2.5-2.02.9-1.3-1.7-2.8-2.62.9-2.9-2.8-2.1-1.6
Heart weight1.31.92.41.61.31.4-1.30.61.31.41.5-1.51.51.41.41.4
Left kidney weight0.30.82.40.20.81.10.6-1.41.6-0.60.30.5-0.5-0.51.00.9
Right kidney weight0.51.33.90.81.31.8-0.0-1.32.0-0.01.0-0.10.1-0.11.61.5
Tail length1.54.46.5-2.5-2.2-1.92.3-0.9-1.2-2.5-2.62.4-2.4-2.3-1.9-1.3
Length with tail0.10.51.4-0.9-1.0-1.00.40.5-0.4-0.5-1.20.5-0.5-0.4-0.9-0.5
Length without tail1.63.46.61.91.30.8-2.52.30.72.61.4-2.42.42.40.70.5
Liver weight, left0.30.41.7-0.20.50.70.7-1.30.8-0.7-0.00.7-0.7-0.70.50.3
Liver weight, right0.50.81.5-1.1-0.8-0.80.9-0.3-0.4-0.9-1.21.0-1.0-0.9-0.9-0.8
Parametrial fat weight4.89.312.7-3.5-2.9-2.53.6-1.8-1.9-3.5-3.43.5-3.5-3.5-2.6-2.5
Retroperitoneal fat weight0.92.97.0-1.5-0.50.02.3-2.60.6-2.2-1.22.3-2.3-2.3-0.10.2
Intraocular pressure0.91.32.61.41.11.1-1.00.10.61.01.6-1.11.11.11.31.6
Extensor digitorum longus weight0.00.20.4-0.4-0.20.00.6-0.40.2-0.5-0.30.5-0.5-0.6-0.00.2
Soleus weight0.30.81.3-1.1-0.8-0.71.1-0.6-0.2-1.0-1.11.1-1.1-1.1-0.7-0.7
Tibialis anterior weight0.20.50.8-0.8-0.8-0.70.9-0.3-0.6-0.8-0.80.8-0.8-0.9-0.7-0.6
Tibia length1.33.69.1-1.8-0.6-0.32.4-3.00.1-2.6-1.32.6-2.6-2.5-0.30.0
Number of licking bursts4.45.37.0-2.6-2.6-2.62.1-0.3-2.5-2.2-2.62.2-2.2-2.1-2.6-2.1
Food consumed during 24 hour testing period0.40.52.1-0.20.30.50.7-1.40.7-0.80.10.9-0.9-0.70.50.4
Times rat made contact with spout4.55.16.8-2.6-2.3-2.22.4-1.3-2.1-2.6-2.42.6-2.6-2.4-2.1-1.7
Mean time between licks in bursts0.91.23.00.80.1-0.4-1.31.7-0.91.30.6-1.61.61.3-0.3-0.8
Mean num. licks in bursts0.91.12.01.21.31.3-0.8-0.51.30.81.3-0.70.70.81.41.1
Std. dev. time between licks in bursts1.41.73.21.51.21.0-1.40.70.81.41.4-1.81.81.41.10.6
Water consumed over 24 hours1.21.42.9-1.1-0.4-0.01.5-1.70.4-1.6-0.91.7-1.7-1.5-0.10.4
Indifference point 0 sec0.50.81.5-1.0-0.8-0.51.1-0.9-0.6-1.2-0.91.1-1.1-1.1-0.6-0.2
Indifference point AUC1.41.66.40.11.11.40.7-2.51.5-0.80.50.9-0.9-0.81.31.9
Indifference point function ln k0.30.40.70.80.60.6-0.70.40.20.80.9-0.80.80.70.60.1
Indifference point function log k0.30.40.70.80.60.6-0.70.40.20.80.9-0.80.80.70.60.1
Delay discounting total patch changes 0 sec0.61.01.9-1.1-0.8-0.51.3-1.2-0.6-1.4-0.91.2-1.2-1.3-0.6-0.2
Delay discounting total patch changes 12 sec0.70.93.4-0.50.30.50.9-1.81.0-1.2-0.31.0-1.0-1.00.51.2
Delay discounting total patch changes 18 sec1.01.34.8-0.70.20.61.2-2.20.7-1.4-0.41.3-1.3-1.20.41.5
Delay discounting total patch changes 24 sec0.50.62.4-0.60.00.31.0-1.50.4-1.0-0.40.9-0.9-1.00.20.8
Delay discounting total patch changes 6 sec1.21.83.1-1.5-0.9-0.51.7-1.4-0.2-1.8-1.41.8-1.8-1.7-0.7-0.1
Delay discounting time to switch 0 sec2.94.417.61.4-0.0-0.7-2.74.2-0.62.60.8-2.72.72.7-0.3-1.2
Delay discounting water rate 0 sec2.84.419.4-0.31.32.01.9-4.42.1-1.90.31.8-1.8-1.91.72.7
Delay discounting water rate 12 sec3.04.49.5-2.1-0.8-0.22.9-3.1-0.0-2.9-1.62.7-2.7-2.9-0.50.4
Delay discounting water rate 18 sec0.70.92.7-0.8-0.10.21.2-1.60.2-1.3-0.51.2-1.2-1.20.10.7
Delay discounting water rate 24 sec1.21.65.6-0.9-0.00.41.7-2.40.2-1.7-0.51.6-1.6-1.60.10.8
Delay discounting water rate 6 sec0.81.24.70.31.31.50.5-2.21.3-0.40.60.4-0.4-0.51.21.5
Locomotor activity2.33.65.2-2.2-2.0-1.91.8-0.1-1.5-1.9-2.32.2-2.2-1.8-2.0-1.8
Locomotor testing distance2.03.45.2-2.2-2.1-2.01.70.2-1.4-1.8-2.32.0-2.0-1.7-2.0-1.5
Locomotor testing rearing1.82.85.7-1.7-1.0-0.62.2-1.8-0.1-2.3-1.42.4-2.4-2.2-0.50.5
Light reinforcement 11.12.13.9-1.5-0.8-0.32.0-1.7-0.2-1.8-1.22.0-2.0-1.9-0.50.6
Light reinforcement 22.93.85.4-2.3-2.3-2.02.1-0.2-1.8-1.8-2.31.9-1.9-2.0-2.1-1.7
Reaction time number correct1.21.73.81.11.71.9-0.4-1.71.70.41.3-0.40.40.41.71.7
Reaction time mean minus median0.10.10.50.1-0.1-0.2-0.50.70.00.4-0.1-0.20.20.5-0.1-0.1
Reaction time mean minus median AUC0.30.31.60.2-0.2-0.4-0.81.3-0.40.70.0-0.50.50.7-0.3-0.3
Reaction time num false alarms0.50.71.10.80.50.5-1.01.00.41.00.7-1.01.01.00.51.0
Reaction time num false alarms AUC0.50.61.40.80.70.7-0.80.70.60.90.8-0.80.80.90.61.2
Reaction time trials correct on left1.21.73.81.11.71.9-0.4-1.71.70.41.3-0.40.40.41.71.7
Reaction time trials on left1.11.53.41.01.61.8-0.3-1.71.60.41.2-0.40.40.31.61.6
Reaction time mean1.31.84.9-0.7-1.7-2.0-0.22.2-1.80.2-1.2-0.30.30.2-1.8-1.7
Reaction time mean AUC1.62.25.4-0.9-1.9-2.2-0.12.3-2.10.2-1.3-0.20.20.1-2.0-1.9
Median of all reaction times1.52.14.5-0.9-1.9-2.10.02.1-2.00.0-1.3-0.10.1-0.0-2.0-1.9
Reaction time omissions0.60.71.3-1.0-1.1-0.90.8-0.0-0.8-0.8-1.10.8-0.8-0.8-1.0-0.4
Reaction time false alarm rate0.40.63.20.4-0.1-0.3-0.91.8-0.30.90.2-0.80.80.9-0.20.1
Reaction time premature initiation rate0.70.91.5-1.1-0.8-0.61.2-0.8-0.5-1.2-0.91.2-1.2-1.2-0.6-0.2
Reaction time premature initiations0.60.83.4-0.50.10.41.1-1.80.5-1.1-0.21.0-1.0-1.10.40.8
Std. dev. reaction times0.71.03.4-0.5-1.2-1.4-0.41.9-1.20.4-0.9-0.30.30.3-1.3-1.1
Reaction time trials completed1.11.53.41.01.61.8-0.3-1.71.60.41.2-0.40.40.31.61.6
Reaction time trials AUC1.01.53.40.91.61.8-0.2-1.81.60.21.2-0.20.20.21.61.6
Social response proportion0.60.61.70.60.2-0.1-0.91.30.21.00.3-1.21.20.9-0.0-0.7
Social responses1.31.73.41.30.80.5-1.71.50.81.60.9-1.81.81.70.60.2
Social time3.14.18.52.12.62.6-1.3-0.62.91.42.2-1.41.41.42.62.2
Conditioned locomotion2.83.35.02.02.22.1-1.5-0.02.21.52.1-1.61.61.52.21.9
Cocaine response after cond. corrected0.20.20.40.50.30.3-0.50.40.00.60.5-0.50.50.50.30.1
Cocaine response after cond. not corrected0.40.40.60.80.60.7-0.70.30.40.80.8-0.60.60.70.60.6
Cocaine response before conditioning0.20.30.80.30.50.80.2-0.80.8-0.10.40.2-0.2-0.10.70.9
Saline control response0.10.10.30.10.20.4-0.0-0.20.50.10.1-0.10.10.10.30.5
Condit. Reinf. active minus inactive responses0.30.41.1-0.5-0.8-0.90.00.7-1.1-0.1-0.60.3-0.3-0.0-0.9-1.0
Condit. Reinf. active-inactive response ratio1.71.83.4-1.4-1.6-1.60.90.3-1.8-0.9-1.41.2-1.2-0.9-1.7-1.6
Condit. Reinf. active responses0.10.10.2-0.2-0.3-0.4-0.10.4-0.4-0.0-0.20.1-0.10.1-0.3-0.5
Condit. Reinf. inactive responses0.20.30.80.50.70.7-0.3-0.30.90.10.5-0.30.30.20.80.7
Condit. Reinf. lever presses0.81.11.9-1.2-1.4-1.30.80.2-1.1-0.9-1.30.8-0.8-0.8-1.3-1.3
Condit. Reinf. lever reinforcers received0.10.10.3-0.1-0.3-0.4-0.20.4-0.40.0-0.20.1-0.10.2-0.3-0.5
Pavlov. Cond. lever latency2.73.75.52.22.32.2-1.90.11.71.92.3-1.71.71.92.11.9
Pavlov. Cond. magazine entry latency1.72.03.4-1.7-1.5-1.51.6-0.2-1.0-1.5-1.81.2-1.2-1.5-1.6-1.2
Pavlov. Cond. change in total contacts2.73.85.9-2.3-2.2-2.21.8-0.2-1.7-1.9-2.41.9-1.9-1.8-2.2-2.0
Pavlov. Cond. index score4.05.27.9-2.7-2.5-2.32.5-0.7-1.6-2.5-2.82.2-2.2-2.5-2.3-1.9
Pavlov. Cond. latency score4.45.58.3-2.8-2.6-2.42.6-0.7-1.7-2.6-2.92.3-2.3-2.5-2.4-2.0
Pavlov. Cond. lever contacts2.94.06.4-2.4-2.4-2.22.0-0.3-1.6-2.0-2.51.8-1.8-2.0-2.2-1.8
Pavlov. Cond. magazine entry number0.91.12.41.31.21.3-1.0-0.10.71.01.5-0.80.81.01.31.0
Pavlov. Cond. intertrial magazine entries0.00.10.20.20.20.4-0.1-0.30.20.00.40.1-0.10.00.40.1
Pavlov. Cond. lever-magazine prob. diff.4.15.38.3-2.8-2.5-2.42.5-0.6-1.8-2.5-2.92.2-2.2-2.4-2.4-2.0
Pavlov. Cond. response bias1.42.03.7-1.6-1.8-1.81.10.5-1.2-1.2-1.90.9-0.9-1.1-1.8-1.6
Conditioned reinforcement - actives2.01.94.01.41.71.8-0.9-0.61.71.11.5-1.01.00.91.72.0
Conditioned reinforcement - inactives0.60.73.1-0.30.30.61.0-1.80.8-0.9-0.10.8-0.8-1.00.50.9
Conditioned locomotion0.00.00.20.0-0.00.20.2-0.50.20.10.1-0.00.0-0.20.10.3
Intermittent access intake day 1-15 change0.20.20.70.20.40.60.2-0.60.8-0.10.20.1-0.1-0.20.50.3
Intermittent access intake escalation0.00.00.20.10.10.20.1-0.00.40.00.0-0.00.00.00.2-0.1
Intermittent access intake escalation 20.20.20.70.10.40.60.2-0.70.9-0.20.20.2-0.2-0.20.50.5
Intermitt. access day 1 inactive lever presses0.91.02.1-1.1-0.7-0.51.4-1.0-0.4-1.3-0.91.3-1.3-1.4-0.6-0.1
Intermitt. access day 15 inactive lever presses1.21.32.9-1.1-0.7-0.51.7-1.4-0.3-1.4-1.01.4-1.4-1.6-0.6-0.8
Intermitt. access escalation Index0.00.00.10.0-0.0-0.1-0.00.3-0.30.10.1-0.10.10.1-0.1-0.3
Intermittent access day 1 total infusions0.80.91.4-1.1-1.2-1.01.1-0.2-1.0-0.7-1.00.8-0.8-1.1-1.1-0.5
Intermittent access day 15 total infusions0.40.40.8-0.7-0.8-0.60.9-0.3-0.5-0.5-0.70.5-0.5-0.9-0.7-0.3
Intermittent access terminal intake (last 3 days)0.30.40.8-0.7-0.9-0.70.80.0-0.6-0.3-0.70.3-0.3-0.7-0.8-0.3
Intermittent access total infusions0.30.40.8-0.6-0.9-0.80.70.2-0.8-0.2-0.70.3-0.3-0.6-0.8-0.5
Intermittent access day 1 locomotion0.60.61.5-0.9-1.1-1.10.70.2-1.2-0.4-0.90.4-0.4-0.7-1.1-0.5
Intermittent access day 15 total locomotion0.20.20.6-0.6-0.5-0.40.8-0.5-0.3-0.6-0.50.4-0.4-0.7-0.4-0.1
Intermittent access total locomotion0.50.61.5-0.7-1.0-1.20.40.7-1.2-0.1-0.80.1-0.1-0.3-1.1-0.8
Intermittent access standard deviation1.71.85.01.10.3-0.1-1.72.2-0.11.80.7-1.91.91.7-0.0-0.4
Cocaine induced anxiety0.30.41.2-0.5-0.6-0.70.50.2-0.7-0.3-0.60.4-0.4-0.5-0.7-1.1
Post-drug Anxiety0.50.62.0-0.5-0.8-0.90.11.1-0.90.1-0.70.1-0.1-0.1-1.0-1.4
Baseline Anxiety0.20.20.40.40.20.2-0.50.60.20.50.2-0.50.50.50.10.5
Lifetime Intake0.00.00.10.0-0.2-0.20.10.3-0.30.3-0.0-0.30.3-0.1-0.20.0
Incentive Sensitization - Responses0.70.72.5-0.6-0.20.21.3-1.60.3-1.0-0.50.9-0.9-1.30.00.3
Incentive Sensitization - Breakpoint0.70.72.5-0.7-0.20.11.3-1.60.3-1.0-0.51.0-1.0-1.30.00.3
Progressive ratio test 1 active lever presses1.51.52.5-1.4-1.6-1.41.3-0.0-1.4-1.1-1.41.1-1.1-1.3-1.4-0.7
Progressive ratio test 1 breakpoint1.01.01.6-1.2-1.3-1.01.2-0.3-1.0-1.0-1.11.0-1.0-1.2-1.1-0.4
Progressive ratio test 1 inactive lever presses0.60.71.7-0.7-0.4-0.01.3-1.30.0-0.9-0.51.0-1.0-1.2-0.10.5
Progressive ratio test 2 active lever presses0.80.82.1-0.8-0.5-0.01.4-1.50.1-1.0-0.61.0-1.0-1.3-0.20.8
Progressive ratio test 2 breakpoint1.11.23.0-1.0-0.6-0.11.7-1.70.0-1.3-0.81.3-1.3-1.6-0.30.7
Progressive ratio test 2 inactive lever presses0.40.41.2-0.5-0.20.01.1-1.10.2-0.7-0.40.7-0.7-1.0-0.10.4
Total sessions with >9 infusions0.20.20.80.30.40.60.1-0.60.50.20.4-0.20.2-0.10.50.9
Short access day 1 total inactive lever presses0.30.41.60.30.70.90.4-1.30.9-0.20.40.1-0.1-0.40.80.3
Short access day 10 total inactive lever presses0.60.62.3-0.40.20.41.1-1.50.6-1.0-0.10.9-0.9-1.10.40.4
Short access day 1 total infusions0.50.60.90.80.90.9-0.5-0.30.80.70.9-0.70.70.50.90.8
Short access day 10 total infusions0.30.30.9-0.5-0.9-0.80.40.7-0.90.1-0.6-0.00.0-0.3-0.9-0.3
Short access total infusions0.20.20.60.40.10.1-0.40.6-0.10.80.3-0.70.70.40.00.2
Short access day 1 locomotion0.40.50.90.70.50.5-0.70.40.30.90.7-1.01.00.70.50.7
Short access day 10 total locomotion1.31.44.80.7-0.0-0.4-1.52.2-0.71.50.4-1.61.61.5-0.4-0.5
Short access total locomotion1.51.62.81.41.10.9-1.50.90.51.71.3-1.61.61.40.81.0
Compulsive drug intake0.60.61.30.71.11.0-0.3-0.91.00.00.9-0.10.10.31.11.1
One hour access (0.3 mA shock)0.91.12.61.01.31.3-0.5-0.81.40.51.1-0.60.60.51.41.6
One hour access (shock baseline)0.20.30.5-0.6-0.7-0.60.7-0.1-0.5-0.4-0.60.4-0.4-0.6-0.6-0.3
Number of responses in last shaping day0.20.20.90.00.40.50.3-1.00.6-0.30.20.3-0.3-0.40.40.5
Context. condit. distance diff. score0.30.30.8-0.7-0.7-0.80.40.5-0.4-0.4-0.90.3-0.3-0.4-0.8-0.2
Locomotion velocity, session 10.70.72.60.00.71.00.7-1.61.2-0.60.30.7-0.7-0.70.90.8
Locomotion distance, session 11.41.83.2-1.5-1.2-0.81.8-1.1-0.4-1.7-1.41.7-1.7-1.8-0.9-0.4
Locomotion velocity, session 22.93.56.7-1.9-0.9-0.32.5-2.50.3-2.5-1.62.6-2.6-2.5-0.50.0
Locomotion distance, session 20.71.12.2-1.0-0.5-0.21.5-1.40.1-1.3-0.81.3-1.3-1.5-0.30.0
Locomotion velocity, session 30.50.61.7-0.00.60.90.6-1.31.2-0.70.20.7-0.7-0.60.80.9
Locomotion distance, session 31.21.32.31.31.51.4-0.9-0.11.40.91.3-1.01.00.91.31.2
Stereotopy head waving bouts, day 30.91.01.8-1.1-1.1-0.81.3-0.6-0.6-1.4-1.01.2-1.2-1.3-0.7-0.4
Stereotopy head waving duration, day 31.11.32.7-1.1-0.8-0.31.6-1.4-0.1-1.6-0.81.6-1.6-1.6-0.20.2
Locomotion velocity, session 70.60.71.80.21.01.00.4-1.31.3-0.40.40.4-0.4-0.41.01.3
Locomotion distance, session 70.50.61.80.30.91.00.3-1.01.1-0.30.50.1-0.1-0.30.91.3
Stereotopy head waving bouts, day 70.30.30.6-0.7-0.8-0.70.50.1-0.5-0.6-0.70.4-0.4-0.5-0.6-0.3
Stereotopy head waving duration, day 70.30.41.0-0.3-0.9-0.9-0.21.0-0.80.1-0.5-0.10.10.2-0.8-0.8
Locomotion velocity, session 80.30.40.8-0.7-0.4-0.20.7-0.50.0-0.7-0.70.9-0.9-0.7-0.30.1
Locomotion distance, session 80.71.01.9-1.2-1.0-0.81.4-0.5-0.3-1.2-1.21.1-1.1-1.3-0.8-0.0
Degree of sensitization distance1.01.02.0-1.0-0.5-0.21.4-1.2-0.0-1.4-0.81.3-1.3-1.4-0.30.3
Degree of sensitization stereotypy0.30.31.20.2-0.2-0.3-0.71.1-0.30.6-0.0-0.80.80.7-0.3-0.1
Condit. Reinf. active minus inactive responses1.11.22.0-1.2-0.6-0.61.3-1.2-0.6-1.4-1.01.4-1.4-1.4-0.7-0.6
Condit. Reinf. active-inactive response ratio0.30.40.6-0.7-0.5-0.60.5-0.3-0.8-0.6-0.60.6-0.6-0.5-0.7-0.8
Condit. Reinf. active responses2.02.43.7-1.8-1.2-1.11.9-1.3-0.8-1.9-1.71.9-1.9-1.9-1.2-0.9
Condit. Reinf. inactive responses1.72.13.0-1.7-1.4-1.31.7-0.7-0.8-1.7-1.71.6-1.6-1.7-1.2-0.9
Incentive salience index mean1.31.53.0-1.3-0.4-0.31.6-1.7-0.0-1.7-1.11.7-1.7-1.6-0.5-0.1
Condit. Reinf. lever presses2.33.05.6-1.9-0.9-0.62.2-2.2-0.2-2.4-1.72.3-2.3-2.3-0.9-0.2
Time in familiar zone, hab. session 10.70.71.7-0.00.60.80.8-1.21.3-0.70.10.7-0.7-0.70.81.2
Time in novel zone, hab. session 10.50.40.90.60.20.1-1.00.8-0.60.90.6-0.90.90.90.1-0.1
Total zone transitions, hab. session 12.73.86.8-2.2-1.6-1.32.6-1.6-0.8-2.5-2.12.3-2.3-2.6-1.3-0.5
Total locomotion distance, hab. session 12.43.56.5-2.0-0.9-0.62.5-2.4-0.2-2.5-1.72.4-2.4-2.6-0.7-0.3
Locomotion velocity, hab. session 12.13.15.8-1.9-0.8-0.52.3-2.2-0.1-2.4-1.62.3-2.3-2.4-0.7-0.2
Time in familiar zone, hab. session 21.21.24.50.80.1-0.3-1.42.1-0.11.40.4-1.51.51.4-0.1-0.1
Time in novel zone, hab. session 20.40.42.0-0.00.50.80.5-1.40.4-0.60.30.6-0.6-0.60.60.6
Total zone transitions, hab. session 23.64.67.2-2.4-2.7-2.52.00.1-2.2-2.0-2.52.0-2.0-2.0-2.4-2.0
Total locomotion distance, hab. session 22.73.64.8-2.2-1.9-1.82.2-0.9-1.6-2.1-2.12.0-2.0-2.1-1.8-1.5
Locomotion velocity, hab. session 22.33.14.1-2.0-1.9-1.71.9-0.7-1.6-1.9-1.91.8-1.8-1.9-1.7-1.6
Novel to familiar place preference ratio0.10.10.1-0.3-0.1-0.10.3-0.4-0.1-0.4-0.20.4-0.4-0.2-0.1-0.1
Novelty place preference0.00.00.0-0.00.10.00.0-0.20.1-0.1-0.10.1-0.10.00.00.1
Time in novel zone, NPP test0.00.00.10.00.30.2-0.0-0.30.2-0.10.10.1-0.10.00.20.2
Total zone transitions, NPP test5.17.310.6-3.2-2.7-2.33.3-1.6-1.5-3.1-3.13.1-3.1-3.3-2.3-1.6
Total locomotion distance, NPP test4.66.48.7-2.9-2.3-2.12.9-1.6-1.6-2.9-2.82.9-2.9-2.9-2.2-1.9
Locomotion velocity, NPP test5.47.710.7-3.3-2.7-2.53.1-1.6-1.9-3.1-3.33.1-3.1-3.1-2.6-2.2
Pavlov. Cond. lever latency1.31.75.31.1-0.0-0.3-1.72.3-0.71.71.0-1.61.61.70.1-0.7
Pavlov. Cond. magazine entry latency0.91.24.40.01.01.30.9-2.11.5-0.90.30.8-0.8-0.91.11.4
Pavlov. Cond. change in total contacts1.21.24.4-0.80.10.51.5-2.10.6-1.5-0.41.2-1.2-1.50.20.6
Pavlov. Cond. index score1.52.06.9-0.90.30.71.7-2.61.1-1.7-0.71.6-1.6-1.70.41.0
Pavlov. Cond. latency score1.31.66.1-0.60.60.91.4-2.51.4-1.4-0.41.3-1.3-1.40.61.3
Pavlov. Cond. lever contacts1.92.25.6-1.4-0.30.12.0-2.40.5-2.0-1.21.8-1.8-2.0-0.30.5
Pavlov. Cond. magazine entry number1.11.45.10.6-0.3-0.7-1.52.3-1.01.50.4-1.31.31.5-0.5-0.9
Pavlov. Cond. intertrial magazine entries0.50.61.10.80.50.3-1.00.80.01.00.7-1.11.11.00.30.1
Pavlov. Cond. lever-magazine prob. diff.1.51.97.0-0.80.50.81.7-2.61.2-1.7-0.51.5-1.5-1.70.51.1
Pavlov. Cond. response bias2.22.77.3-1.4-0.30.22.3-2.70.6-2.2-1.12.1-2.1-2.3-0.10.5
Bone: apparent density0.40.61.8-0.1-0.6-1.0-0.71.4-1.10.6-0.4-0.70.70.6-1.0-0.9
Bone surface0.71.23.30.70.0-0.4-1.41.8-0.51.50.3-1.61.61.4-0.4-0.6
Bone volume0.30.51.70.3-0.2-0.5-0.91.3-0.60.9-0.0-1.01.00.9-0.5-0.4
Bone: connectivity density0.81.33.5-0.0-0.9-1.3-0.91.9-1.61.0-0.4-1.01.00.9-1.3-1.5
Bone: cortical apparent density0.60.81.31.01.00.8-1.10.60.91.00.9-1.01.01.20.80.5
Bone: cortical area0.40.61.3-0.50.20.40.9-1.21.0-0.9-0.50.8-0.8-0.90.31.0
Bone: cortical porosity0.20.20.3-0.4-0.5-0.50.40.2-0.4-0.3-0.40.3-0.3-0.4-0.4-0.6
Bone: cortical porosity0.00.00.1-0.00.00.10.4-0.20.2-0.20.10.2-0.2-0.40.20.0
Bone: cortical thickness0.50.81.9-0.60.20.41.1-1.41.1-1.1-0.61.1-1.1-1.10.30.9
Bone: cortical thickness0.10.10.4-0.2-0.4-0.5-0.00.6-0.40.1-0.4-0.10.10.1-0.5-0.2
Bone: cortical tissue density0.50.71.20.90.90.7-1.10.60.81.00.8-0.90.91.10.70.4
Bone: elastic displacement0.20.20.50.40.40.2-0.70.70.30.60.3-0.50.50.70.20.3
Bone: elastic work0.20.20.6-0.5-0.5-0.70.00.6-0.4-0.1-0.80.2-0.2-0.0-0.7-0.4
Bone: endosteal estimation0.20.51.20.70.30.4-0.90.7-0.10.90.6-1.11.10.90.20.4
Bone: endosteal perimeter0.00.00.0-0.1-0.0-0.00.0-0.0-0.1-0.0-0.1-0.10.1-0.1-0.10.1
Bone: final force0.30.51.1-0.9-0.6-0.50.8-0.4-0.1-0.9-1.00.6-0.6-0.8-0.70.0
Bone: final moment0.20.30.7-0.6-0.10.00.7-0.90.4-0.8-0.70.6-0.6-0.7-0.20.5
Bone: marrow area0.30.61.30.80.40.5-1.00.70.01.00.6-1.21.20.90.30.4
Bone: maximum diameter0.20.41.30.00.50.70.5-1.11.0-0.50.10.4-0.4-0.50.71.1
Bone: maximum force0.20.30.9-0.6-0.7-0.70.20.6-0.7-0.2-0.90.0-0.0-0.2-1.0-0.4
Bone: maximum moment0.00.10.2-0.3-0.2-0.20.10.1-0.1-0.1-0.5-0.10.1-0.1-0.40.1
Bone: minimum diameter0.10.20.6-0.5-0.2-0.00.7-0.70.2-0.6-0.50.4-0.4-0.8-0.10.3
Bone: periosteal estimation0.10.21.00.10.40.70.2-0.70.7-0.20.10.0-0.0-0.20.41.0
Bone: periosteal perimeter0.30.61.1-0.9-0.6-0.51.0-0.60.1-1.0-1.00.8-0.8-1.0-0.50.1
Bone: post-yield work0.20.30.8-0.4-0.7-0.70.20.4-0.9-0.1-0.6-0.10.1-0.2-0.8-0.8
Bone: stiffness0.00.10.2-0.2-0.3-0.30.00.4-0.30.0-0.4-0.20.2-0.0-0.5-0.1
Bone: tissue strength0.10.10.20.40.40.5-0.4-0.00.50.30.3-0.30.30.40.40.4
Bone: trabecular number0.30.41.30.2-0.2-0.5-0.81.2-0.40.8-0.1-0.90.90.7-0.5-0.3
Bone: trabecular spacing0.40.62.1-0.10.60.70.7-1.50.8-0.80.20.8-0.8-0.70.70.6
Bone: trabecular thickness0.50.62.10.3-0.2-0.5-0.91.4-0.70.90.1-1.01.00.8-0.5-0.4
Bone: trabecular tissue density1.82.55.21.42.12.3-0.3-1.82.10.31.8-0.30.30.32.32.0
Breakpoint value in progressive ratio session0.30.31.70.30.50.7-0.1-0.50.70.20.50.0-0.00.10.71.3
Distance traveled before self-admin0.10.10.5-0.20.20.20.3-0.70.3-0.4-0.10.2-0.2-0.40.20.5
Distance traveled after self-admin2.22.54.9-1.7-1.1-0.72.1-1.4-0.8-2.0-1.42.1-2.1-2.2-0.8-0.2
Delta time in closed arm before/after self-admin0.60.61.4-0.8-1.1-1.00.40.5-0.9-0.5-0.90.3-0.3-0.5-1.1-1.2
Delta time in open arm before/after self-admin0.70.72.10.91.00.9-0.7-0.30.60.61.0-0.60.60.71.01.4
Diff in mean of infusions in LGA sessions0.60.73.0-0.00.40.90.7-1.70.8-0.50.20.6-0.6-0.60.71.3
Extinction: sum of active levers before priming0.20.22.10.10.30.40.1-0.70.2-0.00.20.1-0.1-0.10.31.4
Active lever presses in extinction session 60.80.83.40.40.91.20.0-1.31.1-0.10.60.3-0.3-0.21.01.8
Delta distance traveled before/after self-admin3.63.86.1-2.2-1.8-1.52.4-0.9-1.6-2.3-1.92.5-2.5-2.4-1.6-1.2
Delta ambulatory time before/after self-admin3.03.35.0-2.0-1.7-1.42.1-0.9-1.5-2.2-1.72.2-2.2-2.1-1.4-1.1
Time in closed arm before self-admin0.20.30.8-0.1-0.4-0.6-0.30.9-0.90.4-0.2-0.30.30.5-0.6-0.6
Time in closed arm after self-admin1.11.22.9-0.7-1.3-1.50.11.3-1.7-0.1-0.90.0-0.0-0.1-1.5-1.7
Time in open arm before self-admin1.51.63.9-1.1-0.4-0.01.7-2.00.7-1.8-0.81.5-1.5-1.8-0.0-0.1
Time in open arm after self-admin0.70.82.90.00.60.90.6-1.71.0-0.70.30.6-0.6-0.61.01.4
Sum of active levers in priming session hrs 5-62.62.64.71.72.12.2-1.0-1.02.11.01.9-0.90.90.92.21.8
Time to tail flick, vehicle, before self-admin0.10.10.60.40.30.4-0.20.40.40.80.2-0.40.40.30.1-0.1
Time to tail flick, vehicle, after self-admin1.92.06.80.7-0.3-0.8-1.72.6-0.61.60.2-1.61.61.7-0.6-1.9
Time to tail flick, test, before self-admin5.35.27.32.72.72.5-2.30.22.32.52.6-2.32.32.32.41.0
Time to tail flick, test, after self-admin0.40.40.90.60.70.5-0.90.40.40.70.5-0.70.70.90.40.3
Delta time to tail flick, vehicle, before/after SA0.50.41.60.3-0.1-0.5-1.01.3-0.30.60.2-0.70.70.9-0.1-0.7
Delta time to tail flick, test, before/after SA3.83.46.3-2.0-2.3-2.50.91.1-2.3-1.3-2.21.2-1.2-1.0-2.5-2.2
Ambulatory time before self-admin0.30.41.10.40.80.8-0.2-0.70.80.10.5-0.30.30.10.71.0
Ambulatory time after self-admin2.22.44.5-1.7-1.1-0.82.0-1.4-0.8-2.1-1.42.0-2.0-2.1-0.9-0.6
Total heroin consumption0.10.10.2-0.3-0.4-0.30.4-0.4-0.2-0.2-0.20.0-0.0-0.4-0.20.1
Area under the delay curve7.27.710.53.22.92.6-3.21.12.23.03.1-3.03.03.22.71.7
Delay disc. indifference point, 0s delay2.22.36.91.61.61.7-1.4-0.30.91.21.9-1.11.11.41.72.6
Delay disc. indifference point, 16s delay9.39.513.23.63.12.7-3.51.92.33.63.4-3.53.53.62.81.2
Delay disc. indifference point, 2s delay3.53.95.62.22.12.1-2.20.11.61.82.4-1.81.82.22.12.2
Delay disc. indifference point, 24s delay0.80.71.50.90.50.3-1.21.20.21.20.7-1.01.01.20.4-0.1
Delay disc. indifference point, 4s delay5.35.69.12.62.92.9-2.0-1.02.91.72.8-1.91.92.03.02.3
Delay disc. indifference point, 8s delay4.85.06.72.62.42.2-2.50.52.02.32.6-2.42.42.52.31.5
Delay discount exponential model param7.07.410.6-3.1-2.8-2.53.3-1.1-2.3-2.9-3.02.9-2.9-3.3-2.7-1.6
Delay discount hyperbolic model param6.67.09.7-3.1-2.8-2.53.1-0.8-2.3-2.7-3.02.8-2.8-3.1-2.7-1.8
Fecal boli incidents, locomotor time 11.71.85.81.21.71.7-0.7-1.01.60.71.3-0.70.70.81.62.4
Change in fecal boli incidents, locomotor task0.30.30.80.60.60.7-0.4-0.50.90.20.7-0.30.30.40.90.1
Time >=10cm from walls, locomotor time 10.40.52.0-0.10.30.60.6-1.10.5-0.70.20.4-0.4-0.60.61.4
Bouts of movement, locomotor time 10.20.31.1-0.2-0.5-0.70.00.8-1.1-0.0-0.2-0.20.20.0-0.60.6
Total resting periods, locomotor time 10.40.51.5-0.7-0.8-0.90.60.3-1.2-0.6-0.60.4-0.4-0.6-0.80.5
Rest time, locomotor task time 11.11.25.01.11.11.1-0.8-0.20.70.71.3-1.01.00.81.22.2
Distance moved, locomotor task time 10.40.53.5-0.4-0.5-0.7-0.00.7-0.4-0.2-0.50.3-0.30.0-0.6-1.9
Vertical activity count, locomotor time 10.50.51.10.60.50.2-1.10.80.41.00.4-0.70.71.00.3-0.8
Time >=10cm from walls, locomotor time 20.60.62.6-0.10.40.60.7-1.60.9-0.90.20.6-0.6-0.70.70.8
Bouts of movement, locomotor time 20.40.51.2-0.7-0.9-0.80.60.2-0.4-0.8-0.70.5-0.5-0.6-0.6-1.1
Total resting periods, locomotor time 20.30.30.7-0.4-0.8-0.80.20.5-0.5-0.5-0.50.1-0.1-0.2-0.5-0.9
Rest time, locomotor task time 20.50.62.40.50.10.0-0.90.8-0.40.70.4-0.90.90.90.11.5
Distance moved, locomotor task time 20.91.13.2-0.9-0.7-0.71.1-0.6-0.4-1.2-0.81.3-1.3-1.1-0.6-1.8
Vertical activity count, locomotor time 20.30.30.70.60.80.8-0.4-0.40.80.50.7-0.30.30.40.7-0.3
Weight adjusted by age0.20.21.6-0.3-0.2-0.00.3-0.30.1-0.5-0.20.6-0.6-0.5-0.0-1.2
Seeking ratio, delayed vs. immediate footshock1.21.42.91.20.60.6-1.41.40.21.71.0-1.71.71.50.40.5
Locomotion in novel chamber0.70.81.21.00.90.9-1.10.20.81.00.9-1.11.11.10.80.6
Locomotion in novel chamber post-restriction2.63.16.01.92.32.4-1.2-1.12.01.52.0-1.41.41.22.11.8
Progressive ratio0.40.41.10.60.40.2-1.00.80.40.80.3-0.80.81.00.20.3
Food seeking constrained by brief footshock0.20.20.4-0.4-0.5-0.60.10.7-0.6-0.3-0.50.2-0.2-0.2-0.6-0.3
Seeking ratio, punishment vs. effort0.30.40.9-0.6-0.4-0.30.9-0.4-0.4-0.8-0.50.9-0.9-1.0-0.3-0.4
Run reversals in cocaine runway, females0.50.51.7-0.40.00.30.6-1.30.6-1.0-0.30.7-0.7-0.70.21.1
Run reversals in cocaine runway, males0.20.21.40.10.10.40.3-0.50.4-0.40.30.1-0.1-0.30.51.2
Latency to leave start box in cocaine runway1.11.23.0-1.0-0.5-0.11.6-1.50.1-1.3-0.81.3-1.3-1.7-0.3-0.3
Latency to leave start box in cocaine runway, F0.20.20.5-0.5-0.4-0.30.6-0.1-0.4-0.3-0.50.4-0.4-0.7-0.5-0.5
Latency to leave start box in cocaine runway, M2.72.66.2-1.4-0.5-0.02.2-2.50.4-2.2-1.02.1-2.1-2.2-0.10.2
Cd content in liver1.31.42.61.51.21.4-1.00.11.21.11.6-1.11.11.01.51.1
Co content in liver0.00.00.10.00.10.20.2-0.4-0.1-0.20.20.2-0.2-0.20.2-0.0
Cu content in liver1.51.83.61.41.91.8-0.9-0.81.70.81.5-0.80.80.91.71.5
Fe content in liver0.30.30.70.50.30.1-0.70.80.40.80.2-0.80.80.70.10.4
K content in liver1.51.54.7-0.4-1.2-1.6-0.62.2-1.70.6-0.8-0.60.60.6-1.5-1.6
Mg content in liver1.21.22.31.10.80.4-1.51.50.51.50.7-1.51.51.50.40.5
Mn content in liver0.70.81.5-0.9-0.6-0.81.0-0.8-1.2-1.1-0.61.1-1.1-1.0-0.7-0.7
Na content in liver0.00.00.1-0.20.20.00.1-0.20.3-0.2-0.40.2-0.2-0.1-0.10.3
Rb content in liver4.65.79.02.62.31.8-2.91.71.63.02.2-3.03.02.91.61.3
Se content in liver0.20.20.50.10.30.40.4-0.70.5-0.40.40.4-0.4-0.40.60.7
Sr content in liver0.40.41.0-0.4-0.20.20.9-1.00.1-0.9-0.10.9-0.9-0.90.20.2
Zn content in liver6.06.68.82.92.92.9-2.30.12.72.43.0-2.42.42.32.92.7