Acsl5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016265 0.03 0.02 2.8e-03 0.01 0.02 0.01 0.02 2.3e-02 2.1e-03 3.6e-02 3.4e-03
2 Adipose isoform ratio ENSRNOT00000103067 0.03 0.02 1.0e-03 0.02 0.02 0.02 0.02 9.2e-04 4.2e-03 3.6e-03 2.1e-03
3 Liver gene expression ENSRNOG00000016265 0.05 0.04 8.0e-05 0.03 0.02 0.02 0.03 1.4e-04 1.0e-03 1.4e-03 3.8e-04
4 Liver mRNA stability ENSRNOG00000016265 0.06 0.04 4.1e-07 0.05 0.05 0.06 0.06 7.0e-06 2.4e-06 8.6e-07 9.4e-07
5 NAcc gene expression ENSRNOG00000016265 0.09 0.06 1.1e-06 0.07 0.07 0.07 0.07 4.0e-06 6.5e-06 4.6e-06 6.2e-06
6 NAcc isoform ratio ENSRNOT00000110033 0.03 0.03 8.4e-03 0.02 0 0 0 2.2e-02 1.5e-01 2.2e-01 1.8e-01
7 OFC gene expression ENSRNOG00000016265 0.32 0.16 2.2e-06 0.16 0.19 0.14 0.16 1.1e-04 2.8e-05 4.0e-04 1.4e-04
8 PL intron excision ratio chr1:254294502:254310070 0.17 0.19 3.8e-04 0.01 0.04 0.05 0.02 3.8e-02 5.9e-04 1.4e-04 7.4e-03
9 PL intron excision ratio chr1:254325683:254327918 0.04 0.03 4.6e-03 0.03 0.02 0 0.02 3.1e-03 1.2e-02 2.4e-01 9.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail9.631.139.15.0-6.36.36.16.05.9-5.9-3.94.2
BMI without tail3.98.110.72.3-3.33.33.13.23.1-3.0-2.01.7
Body weight11.548.660.46.5-7.77.77.87.67.1-7.5-4.75.6
Epididymis fat weight14.934.745.64.8-6.86.86.46.76.7-6.4-3.53.7
Glucose4.36.67.52.7-2.62.62.72.52.7-2.7-2.12.5
Heart weight2.73.97.11.6-2.22.22.01.91.7-1.7-2.71.5
Left kidney weight5.616.020.74.6-3.63.64.23.53.4-3.9-4.54.5
Right kidney weight6.217.620.94.5-4.14.14.64.03.6-4.1-4.44.3
Tail length0.20.61.40.3-1.01.00.81.20.8-0.8-0.50.1
Length with tail2.79.812.72.9-3.43.43.53.63.0-3.4-2.12.6
Length without tail6.714.617.93.9-4.14.14.24.03.7-4.1-2.63.5
Liver weight, left2.94.78.31.3-2.52.52.32.82.9-2.40.50.8
Liver weight, right8.313.817.93.4-4.14.14.14.24.2-4.2-1.42.9
Parametrial fat weight7.013.721.52.6-4.44.43.94.64.6-4.1-0.71.7
Retroperitoneal fat weight14.146.760.06.0-7.67.67.57.77.7-7.3-4.24.9
Intraocular pressure3.24.67.41.1-2.72.72.22.62.7-2.3-0.70.6
Extensor digitorum longus weight0.52.03.11.1-1.61.61.61.81.5-1.7-0.50.9
Soleus weight4.914.217.94.2-3.43.44.13.84.0-4.1-2.64.0
Tibialis anterior weight0.00.10.4-0.60.2-0.2-0.20.1-0.30.10.6-0.6
Tibia length1.85.06.02.5-2.42.42.32.01.8-2.2-2.12.4
Number of licking bursts0.40.51.2-0.2-1.11.10.30.60.5-0.50.8-0.6
Food consumed during 24 hour testing period0.10.10.50.3-0.30.30.2-0.0-0.5-0.1-0.70.3
Times rat made contact with spout1.41.62.11.3-1.31.31.51.41.2-1.5-0.71.1
Mean time between licks in bursts0.10.10.5-0.6-0.20.2-0.10.10.00.00.3-0.7
Mean num. licks in bursts1.01.23.01.5-0.10.11.10.70.6-0.8-1.61.7
Std. dev. time between licks in bursts0.60.82.3-1.30.0-0.0-0.7-0.3-0.50.51.3-1.5
Water consumed over 24 hours0.91.11.81.3-0.90.91.00.80.5-1.0-1.31.3
Indifference point 0 sec3.25.16.81.9-2.62.62.52.52.5-2.5-1.51.3
Indifference point AUC0.50.51.8-0.4-0.50.50.20.90.9-0.51.3-0.6
Indifference point function ln k0.20.30.90.20.3-0.3-0.3-0.7-0.70.4-0.90.3
Indifference point function log k0.20.30.90.20.3-0.3-0.3-0.7-0.70.4-0.90.3
Delay discounting total patch changes 0 sec2.94.76.51.7-2.52.52.42.52.5-2.4-1.11.1
Delay discounting total patch changes 12 sec0.71.02.10.2-1.11.10.91.41.2-1.10.4-0.0
Delay discounting total patch changes 18 sec1.92.54.50.5-1.91.91.62.12.0-1.80.8-0.1
Delay discounting total patch changes 24 sec1.21.52.9-0.3-1.11.11.01.61.5-1.11.7-1.0
Delay discounting total patch changes 6 sec3.65.48.31.6-2.92.92.52.82.7-2.6-0.80.9
Delay discounting time to switch 0 sec0.71.02.2-0.61.2-1.2-0.9-1.2-1.51.10.0-0.5
Delay discounting water rate 0 sec0.71.22.30.9-1.21.21.01.21.5-1.2-0.40.7
Delay discounting water rate 12 sec0.91.32.20.8-1.41.41.11.31.5-1.3-0.00.4
Delay discounting water rate 18 sec1.21.62.11.2-1.41.41.11.11.4-1.2-1.41.1
Delay discounting water rate 24 sec2.53.55.81.6-2.42.41.92.01.9-2.0-0.91.2
Delay discounting water rate 6 sec0.50.71.21.1-1.11.10.70.40.5-0.8-0.51.0
Locomotor activity1.32.03.81.6-1.41.41.51.00.9-1.3-1.91.5
Locomotor testing distance2.03.36.62.2-1.51.51.91.21.1-1.6-2.62.2
Locomotor testing rearing1.01.52.41.5-1.21.21.31.00.8-1.2-1.61.3
Light reinforcement 11.01.82.3-1.31.4-1.4-1.5-1.5-1.31.50.7-1.2
Light reinforcement 21.52.02.9-1.21.5-1.5-1.6-1.7-1.61.50.7-0.9
Reaction time number correct1.11.62.70.8-1.51.51.21.61.5-1.40.20.5
Reaction time mean minus median0.20.20.50.2-0.70.70.30.50.5-0.40.10.1
Reaction time mean minus median AUC0.50.70.80.9-0.80.80.80.80.9-0.8-0.60.8
Reaction time num false alarms0.00.00.2-0.2-0.00.0-0.00.30.4-0.00.1-0.3
Reaction time num false alarms AUC0.00.00.1-0.00.1-0.10.00.30.4-0.0-0.20.0
Reaction time trials correct on left1.11.62.70.8-1.51.51.21.61.5-1.40.20.5
Reaction time trials on left1.21.72.80.8-1.61.61.31.71.6-1.40.20.5
Reaction time mean0.10.10.30.40.1-0.10.0-0.3-0.10.1-0.50.5
Reaction time mean AUC0.10.20.4-0.10.5-0.5-0.4-0.7-0.40.5-0.20.1
Median of all reaction times0.10.20.50.50.3-0.3-0.0-0.5-0.20.2-0.60.7
Reaction time omissions0.20.20.60.2-0.80.80.40.40.4-0.4-0.40.1
Reaction time false alarm rate0.30.40.7-0.60.8-0.8-0.7-0.7-0.50.8-0.1-0.5
Reaction time premature initiation rate1.01.43.31.7-0.50.51.30.90.9-1.1-1.21.8
Reaction time premature initiations2.43.55.12.2-1.51.52.11.91.8-2.0-1.22.2
Std. dev. reaction times0.71.01.40.9-1.21.21.01.01.1-1.0-0.70.7
Reaction time trials completed1.21.72.80.8-1.61.61.31.71.6-1.40.20.5
Reaction time trials AUC1.21.83.00.8-1.71.71.31.71.6-1.50.10.5
Social response proportion3.74.15.62.4-1.81.82.21.71.9-2.0-2.12.3
Social responses3.74.87.71.6-2.52.52.42.72.8-2.5-0.81.0
Social time1.72.23.11.7-1.11.11.61.71.8-1.6-1.11.6
Conditioned locomotion0.00.00.10.10.2-0.2-0.1-0.20.10.10.10.1
Cocaine response after cond. corrected0.91.01.9-0.51.3-1.3-0.9-1.2-1.41.1-0.6-0.2
Cocaine response after cond. not corrected2.02.23.6-1.11.9-1.9-1.4-1.7-1.81.60.2-0.7
Cocaine response before conditioning1.01.22.5-1.20.9-0.9-1.1-0.9-0.71.01.6-1.2
Saline control response0.30.40.8-0.30.9-0.9-0.7-0.8-0.70.7-0.1-0.1
Condit. Reinf. active minus inactive responses1.31.65.6-2.0-0.50.5-1.1-0.4-0.60.91.3-2.4
Condit. Reinf. active-inactive response ratio1.51.64.3-2.00.0-0.0-1.3-0.9-1.21.21.0-2.1
Condit. Reinf. active responses0.81.13.5-1.4-1.11.1-0.30.40.30.11.2-1.9
Condit. Reinf. inactive responses0.30.40.7-0.0-0.70.70.50.80.8-0.60.5-0.4
Condit. Reinf. lever presses0.50.72.5-1.3-0.50.5-0.50.0-0.20.31.2-1.6
Condit. Reinf. lever reinforcers received0.81.13.9-1.5-0.90.9-0.50.20.20.21.3-2.0
Pavlov. Cond. lever latency0.91.34.01.60.3-0.30.6-0.00.3-0.4-2.02.0
Pavlov. Cond. magazine entry latency1.11.32.50.6-1.21.21.31.61.4-1.30.40.3
Pavlov. Cond. change in total contacts0.50.71.4-0.8-0.90.90.20.80.6-0.41.1-1.2
Pavlov. Cond. index score0.60.81.3-0.4-1.11.10.61.10.9-0.71.0-0.8
Pavlov. Cond. latency score0.60.81.2-0.4-1.11.10.61.10.9-0.71.1-0.8
Pavlov. Cond. lever contacts0.30.41.3-0.8-0.60.6-0.10.40.1-0.11.0-1.1
Pavlov. Cond. magazine entry number0.91.12.1-0.41.2-1.2-1.1-1.4-1.31.2-0.4-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.1-0.40.4-0.3-0.2-0.10.1-0.2-0.1
Pavlov. Cond. lever-magazine prob. diff.0.60.71.3-0.3-1.11.10.51.00.9-0.70.9-0.7
Pavlov. Cond. response bias0.40.61.0-0.5-1.01.00.40.90.7-0.50.8-0.9
Conditioned reinforcement - actives0.20.20.3-0.50.5-0.5-0.5-0.3-0.50.50.1-0.2
Conditioned reinforcement - inactives0.40.40.80.2-0.70.70.60.90.9-0.70.6-0.2
Conditioned locomotion0.60.72.4-0.50.8-0.8-0.8-0.8-0.80.61.6-0.4
Intermittent access intake day 1-15 change2.22.14.40.8-1.71.71.32.12.0-1.5-0.30.4
Intermittent access intake escalation3.73.65.81.5-2.12.11.92.42.3-2.0-1.11.2
Intermittent access intake escalation 22.02.03.11.2-1.61.61.41.71.8-1.5-0.60.8
Intermitt. access day 1 inactive lever presses1.31.42.60.5-1.41.41.11.61.5-1.30.7-0.2
Intermitt. access day 15 inactive lever presses0.10.10.3-0.3-0.20.2-0.00.20.30.00.1-0.5
Intermitt. access escalation Index0.20.20.40.6-0.40.40.40.30.1-0.4-0.30.6
Intermittent access day 1 total infusions0.40.41.9-0.7-0.20.2-0.30.10.10.01.4-1.0
Intermittent access day 15 total infusions1.21.32.70.3-1.51.50.91.71.6-1.10.3-0.1
Intermittent access terminal intake (last 3 days)0.40.51.0-0.1-0.90.90.41.00.9-0.60.5-0.4
Intermittent access total infusions0.50.50.9-0.2-0.90.90.30.80.8-0.61.0-0.5
Intermittent access day 1 locomotion0.00.00.10.10.1-0.1-0.1-0.3-0.30.1-0.10.2
Intermittent access day 15 total locomotion1.61.72.80.9-1.61.61.21.61.7-1.4-0.50.5
Intermittent access total locomotion0.10.10.30.5-0.30.30.30.20.3-0.4-0.30.6
Intermittent access standard deviation1.11.22.6-0.2-1.31.30.61.21.3-0.91.6-0.8
Cocaine induced anxiety2.63.05.7-0.52.2-2.2-1.7-2.2-2.41.8-0.20.1
Post-drug Anxiety0.30.30.90.10.6-0.6-0.4-0.6-0.90.5-0.00.4
Baseline Anxiety5.05.38.61.2-2.92.92.32.92.9-2.50.50.5
Lifetime Intake0.60.71.3-0.2-1.01.00.40.90.9-0.71.1-0.6
Incentive Sensitization - Responses0.70.72.00.2-1.11.10.61.11.4-0.80.1-0.1
Incentive Sensitization - Breakpoint0.80.82.10.2-1.11.10.61.21.4-0.80.2-0.2
Progressive ratio test 1 active lever presses0.30.30.70.1-0.90.90.50.60.6-0.6-0.1-0.2
Progressive ratio test 1 breakpoint0.10.10.4-0.4-0.30.3-0.00.10.0-0.00.4-0.7
Progressive ratio test 1 inactive lever presses0.30.31.4-0.4-0.30.3-0.10.50.4-0.21.2-0.7
Progressive ratio test 2 active lever presses1.41.52.80.5-1.61.61.11.61.7-1.2-0.40.1
Progressive ratio test 2 breakpoint1.21.32.70.4-1.51.50.91.61.6-1.1-0.1-0.0
Progressive ratio test 2 inactive lever presses0.50.61.1-0.2-1.01.00.40.91.0-0.60.7-0.7
Total sessions with >9 infusions3.84.25.32.0-2.32.32.32.32.2-2.2-0.81.5
Short access day 1 total inactive lever presses1.01.21.90.8-1.21.21.21.41.4-1.20.40.3
Short access day 10 total inactive lever presses0.30.40.80.4-0.60.60.60.80.9-0.70.1-0.0
Short access day 1 total infusions0.50.51.00.6-0.90.90.81.00.8-0.80.30.3
Short access day 10 total infusions0.30.30.9-0.7-0.00.0-0.3-0.3-0.30.20.9-0.9
Short access total infusions0.30.41.4-0.3-0.70.70.20.60.5-0.41.2-0.6
Short access day 1 locomotion0.20.20.8-0.0-0.50.50.20.50.3-0.40.9-0.3
Short access day 10 total locomotion1.01.12.21.5-0.80.81.10.50.4-0.9-1.31.5
Short access total locomotion0.60.61.11.1-0.60.60.80.30.4-0.7-1.01.0
Compulsive drug intake0.70.73.4-0.90.2-0.2-0.7-0.1-0.20.41.8-0.9
One hour access (0.3 mA shock)1.51.83.1-0.3-1.61.60.61.71.6-1.11.8-0.8
One hour access (shock baseline)1.11.21.90.7-1.41.41.11.41.3-1.2-0.40.4
Number of responses in last shaping day0.20.20.40.5-0.20.20.60.50.5-0.5-0.50.6
Context. condit. distance diff. score0.30.31.20.10.4-0.4-0.3-0.6-0.70.5-1.10.4
Locomotion velocity, session 13.13.34.4-2.01.6-1.6-1.9-1.7-1.71.82.1-1.9
Locomotion distance, session 10.30.30.7-0.30.7-0.7-0.6-0.8-0.60.7-0.1-0.1
Locomotion velocity, session 20.60.71.20.11.1-1.1-0.5-1.0-1.10.8-0.50.5
Locomotion distance, session 21.42.02.51.4-1.51.51.61.51.6-1.6-0.91.2
Locomotion velocity, session 30.10.10.60.3-0.10.10.2-0.1-0.30.0-0.80.5
Locomotion distance, session 30.80.83.61.0-0.30.30.70.30.2-0.4-1.91.4
Stereotopy head waving bouts, day 30.10.10.10.1-0.30.30.30.30.4-0.30.00.1
Stereotopy head waving duration, day 31.11.32.0-1.30.8-0.8-1.3-1.1-1.01.11.3-1.4
Locomotion velocity, session 70.00.00.10.0-0.20.20.10.30.2-0.1-0.20.1
Locomotion distance, session 70.10.10.40.20.2-0.2-0.1-0.1-0.10.1-0.60.5
Stereotopy head waving bouts, day 70.00.10.2-0.1-0.40.40.00.1-0.1-0.00.1-0.3
Stereotopy head waving duration, day 70.30.31.00.1-1.01.00.30.50.4-0.50.2-0.2
Locomotion velocity, session 81.41.62.5-0.91.6-1.6-1.4-1.6-1.31.40.9-0.7
Locomotion distance, session 80.10.21.10.40.2-0.2-0.1-0.4-0.30.2-1.00.6
Degree of sensitization distance1.41.43.2-1.40.8-0.8-1.2-0.8-0.81.01.8-1.5
Degree of sensitization stereotypy0.10.10.3-0.1-0.50.50.20.30.1-0.20.2-0.3
Condit. Reinf. active minus inactive responses0.20.30.6-0.70.3-0.3-0.4-0.4-0.50.6-0.3-0.6
Condit. Reinf. active-inactive response ratio0.60.61.0-1.00.6-0.6-0.8-0.8-0.91.0-0.2-0.9
Condit. Reinf. active responses0.10.10.3-0.2-0.40.40.40.50.3-0.2-0.3-0.3
Condit. Reinf. inactive responses0.40.40.90.1-0.80.80.70.90.8-0.70.4-0.1
Incentive salience index mean0.80.91.5-1.21.0-1.0-0.9-0.9-1.01.20.1-1.0
Condit. Reinf. lever presses0.91.21.7-1.31.1-1.1-1.0-1.0-1.01.20.9-1.2
Time in familiar zone, hab. session 10.40.41.00.10.7-0.7-0.4-0.8-1.00.6-0.80.4
Time in novel zone, hab. session 10.70.71.3-0.1-1.21.20.40.91.1-0.70.7-0.5
Total zone transitions, hab. session 11.72.32.81.5-1.51.51.71.61.4-1.6-1.41.5
Total locomotion distance, hab. session 10.00.10.2-0.0-0.40.40.20.30.1-0.20.0-0.1
Locomotion velocity, hab. session 10.00.00.1-0.1-0.30.30.20.20.1-0.1-0.0-0.1
Time in familiar zone, hab. session 22.02.13.80.5-1.91.91.41.81.8-1.60.10.0
Time in novel zone, hab. session 20.70.71.30.11.1-1.1-0.6-1.0-1.10.8-0.60.5
Total zone transitions, hab. session 22.83.64.61.7-1.91.92.12.01.8-1.9-1.91.7
Total locomotion distance, hab. session 21.52.02.91.3-1.41.41.71.51.4-1.5-1.21.2
Locomotion velocity, hab. session 20.91.21.71.0-1.01.01.31.11.1-1.1-1.00.9
Novel to familiar place preference ratio0.10.10.3-0.40.1-0.1-0.3-0.00.10.20.4-0.5
Novelty place preference0.10.10.2-0.3-0.10.1-0.20.10.20.00.4-0.5
Time in novel zone, NPP test0.20.20.4-0.2-0.60.60.10.50.6-0.30.4-0.5
Total zone transitions, NPP test2.13.04.01.4-1.91.92.02.01.9-1.9-0.91.2
Total locomotion distance, NPP test1.41.92.81.0-1.61.61.71.61.5-1.6-0.60.8
Locomotion velocity, NPP test0.71.01.60.9-1.01.01.31.11.0-1.1-0.50.8
Pavlov. Cond. lever latency0.50.71.10.5-1.01.00.81.11.0-0.9-0.20.4
Pavlov. Cond. magazine entry latency0.50.61.10.7-0.50.51.01.01.1-0.9-0.40.7
Pavlov. Cond. change in total contacts0.10.10.30.40.1-0.10.30.1-0.0-0.1-0.50.6
Pavlov. Cond. index score0.30.30.50.7-0.20.20.70.50.7-0.6-0.40.7
Pavlov. Cond. latency score0.10.20.40.6-0.00.00.60.40.5-0.4-0.40.6
Pavlov. Cond. lever contacts0.40.50.7-0.60.9-0.9-0.7-0.8-0.70.80.4-0.5
Pavlov. Cond. magazine entry number1.41.82.7-1.40.9-0.9-1.7-1.4-1.61.51.0-1.4
Pavlov. Cond. intertrial magazine entries0.20.20.50.3-0.70.70.40.50.2-0.4-0.60.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.5-0.10.10.60.50.7-0.5-0.20.5
Pavlov. Cond. response bias0.20.20.40.5-0.00.00.60.40.5-0.4-0.50.6
Bone: apparent density1.32.13.80.7-2.02.01.41.81.6-1.6-0.30.4
Bone surface0.61.12.50.7-1.61.61.01.10.9-1.1-0.50.5
Bone volume2.94.98.01.7-2.82.82.22.52.3-2.4-1.01.3
Bone: connectivity density0.10.10.3-0.40.1-0.1-0.4-0.2-0.50.3-0.0-0.3
Bone: cortical apparent density1.01.32.40.51.3-1.3-0.5-1.3-1.20.9-1.51.0
Bone: cortical area7.110.719.32.3-4.44.43.23.63.4-3.4-1.81.7
Bone: cortical porosity0.10.10.4-0.5-0.30.3-0.10.30.0-0.10.6-0.6
Bone: cortical porosity0.20.30.5-0.3-0.60.60.20.70.5-0.50.6-0.5
Bone: cortical thickness3.96.59.92.1-3.13.12.62.72.5-2.6-2.01.8
Bone: cortical thickness2.22.63.31.6-1.81.81.61.41.5-1.6-1.41.5
Bone: cortical tissue density1.11.42.20.41.5-1.5-0.7-1.5-1.31.1-1.40.9
Bone: elastic displacement0.00.00.0-0.2-0.10.10.00.20.1-0.0-0.1-0.2
Bone: elastic work1.72.33.21.6-1.41.41.61.41.3-1.4-1.81.7
Bone: endosteal estimation1.83.86.51.3-2.62.61.92.32.2-2.1-0.40.9
Bone: endosteal perimeter3.16.412.21.9-3.53.52.42.62.6-2.6-1.31.4
Bone: final force2.03.36.41.4-2.52.51.71.81.9-1.8-1.01.1
Bone: final moment2.74.57.91.6-2.82.82.12.22.2-2.1-1.21.3
Bone: marrow area1.94.06.71.4-2.62.62.02.32.3-2.2-0.51.0
Bone: maximum diameter5.710.419.32.2-4.44.43.13.63.6-3.5-0.91.4
Bone: maximum force1.62.95.51.3-2.42.41.51.61.7-1.6-1.21.0
Bone: maximum moment2.23.86.81.5-2.62.61.82.02.0-2.0-1.31.2
Bone: minimum diameter3.56.510.81.8-3.33.32.52.92.6-2.7-1.51.3
Bone: periosteal estimation5.611.519.32.5-4.44.43.43.83.6-3.6-1.61.9
Bone: periosteal perimeter7.612.722.52.7-4.74.73.43.93.7-3.8-1.72.0
Bone: post-yield work0.30.41.2-0.9-0.30.3-0.5-0.2-0.00.30.9-1.1
Bone: stiffness0.30.51.60.4-1.31.30.40.40.4-0.5-0.80.3
Bone: tissue strength0.20.20.4-0.70.4-0.4-0.5-0.4-0.40.60.3-0.6
Bone: trabecular number0.20.30.6-0.1-0.80.80.30.70.4-0.50.2-0.3
Bone: trabecular spacing0.20.20.3-0.50.6-0.6-0.5-0.4-0.30.50.5-0.5
Bone: trabecular thickness4.55.48.91.7-3.03.02.32.72.7-2.6-0.41.1
Bone: trabecular tissue density0.10.10.20.4-0.40.40.1-0.3-0.1-0.0-0.40.4
Breakpoint value in progressive ratio session0.40.41.0-0.5-0.70.70.10.60.6-0.31.0-0.9
Distance traveled before self-admin0.90.93.91.00.6-0.60.3-0.3-0.40.1-2.01.6
Distance traveled after self-admin1.92.14.92.0-0.70.71.40.80.8-1.1-2.12.2
Delta time in closed arm before/after self-admin0.30.21.00.60.1-0.10.3-0.00.2-0.1-1.00.9
Delta time in open arm before/after self-admin0.50.51.4-0.3-0.70.70.20.80.7-0.51.2-0.8
Diff in mean of infusions in LGA sessions2.52.83.6-1.81.6-1.6-1.9-1.9-1.81.90.7-1.6
Extinction: sum of active levers before priming0.60.62.7-0.90.2-0.2-0.6-0.2-0.20.41.6-1.0
Active lever presses in extinction session 60.40.40.90.3-0.70.70.50.80.9-0.60.70.0
Delta distance traveled before/after self-admin2.02.23.01.4-1.71.71.51.61.7-1.6-0.51.1
Delta ambulatory time before/after self-admin1.71.83.00.9-1.71.71.31.61.7-1.50.30.4
Time in closed arm before self-admin0.20.21.10.5-0.30.30.50.20.1-0.3-1.10.3
Time in closed arm after self-admin0.20.31.2-0.10.5-0.5-0.1-0.5-0.50.4-1.10.1
Time in open arm before self-admin1.92.12.7-1.21.6-1.6-1.6-1.5-1.41.41.5-0.8
Time in open arm after self-admin1.51.67.2-1.40.6-0.6-1.2-0.5-0.30.72.7-1.5
Sum of active levers in priming session hrs 5-62.22.12.9-1.31.5-1.5-1.6-1.5-1.51.41.7-1.0
Time to tail flick, vehicle, before self-admin1.31.32.20.9-1.41.41.21.51.3-1.30.20.6
Time to tail flick, vehicle, after self-admin0.10.10.50.50.1-0.10.10.0-0.1-0.20.20.7
Time to tail flick, test, before self-admin1.91.94.41.8-0.70.71.30.90.9-1.2-2.11.9
Time to tail flick, test, after self-admin1.71.72.61.0-1.61.61.51.61.4-1.4-0.40.7
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.20.5-0.5-0.4-0.5-0.60.4-0.00.0
Delta time to tail flick, test, before/after SA0.70.61.10.2-1.11.10.70.90.9-0.70.7-0.3
Ambulatory time before self-admin1.41.45.61.5-0.20.21.00.30.2-0.6-2.41.9
Ambulatory time after self-admin1.92.14.72.1-0.90.91.51.01.0-1.3-1.62.2
Total heroin consumption1.01.22.30.3-1.41.41.11.51.5-1.1-0.2-0.0
Area under the delay curve0.50.50.80.0-0.90.90.70.90.7-0.70.8-0.3
Delay disc. indifference point, 0s delay0.90.91.60.8-1.21.21.11.20.9-1.20.10.5
Delay disc. indifference point, 16s delay0.40.41.8-0.80.0-0.0-0.3-0.1-0.10.21.4-1.0
Delay disc. indifference point, 2s delay0.10.10.20.3-0.20.20.30.30.1-0.40.50.3
Delay disc. indifference point, 24s delay0.70.73.1-0.6-0.70.70.20.60.7-0.41.7-1.1
Delay disc. indifference point, 4s delay0.20.20.6-0.5-0.00.0-0.1-0.1-0.30.10.8-0.7
Delay disc. indifference point, 8s delay2.02.03.80.6-1.81.81.51.91.7-1.50.40.1
Delay discount exponential model param0.60.61.0-0.01.0-1.0-0.7-1.0-0.80.8-0.90.4
Delay discount hyperbolic model param0.40.40.8-0.10.8-0.8-0.6-0.9-0.70.7-0.70.2
Fecal boli incidents, locomotor time 10.10.10.4-0.40.1-0.1-0.40.00.10.20.7-0.4
Change in fecal boli incidents, locomotor task0.10.10.2-0.20.4-0.4-0.2-0.2-0.30.3-0.4-0.2
Time >=10cm from walls, locomotor time 10.90.91.6-0.71.3-1.3-1.1-0.9-1.01.00.7-0.2
Bouts of movement, locomotor time 11.01.22.4-0.0-1.31.30.81.61.5-1.00.7-0.4
Total resting periods, locomotor time 11.11.22.40.1-1.41.40.81.51.5-1.00.6-0.3
Rest time, locomotor task time 10.40.40.70.6-0.70.70.60.80.8-0.6-0.50.5
Distance moved, locomotor task time 10.00.00.10.20.0-0.00.20.0-0.1-0.2-0.10.4
Vertical activity count, locomotor time 10.70.82.60.30.8-0.8-0.2-1.0-1.10.5-1.60.6
Time >=10cm from walls, locomotor time 20.50.51.20.4-0.70.70.71.01.1-0.80.20.3
Bouts of movement, locomotor time 21.01.11.6-1.01.1-1.1-1.2-1.0-1.21.20.6-0.7
Total resting periods, locomotor time 20.50.60.8-0.80.8-0.8-0.9-0.6-0.90.80.6-0.6
Rest time, locomotor task time 20.10.10.30.40.1-0.10.0-0.3-0.6-0.0-0.20.3
Distance moved, locomotor task time 20.20.20.5-0.3-0.40.40.20.60.7-0.30.4-0.4
Vertical activity count, locomotor time 20.20.30.40.3-0.60.60.50.50.6-0.5-0.50.2
Weight adjusted by age7.58.411.02.7-3.03.03.12.92.9-2.8-3.32.5
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.10.1-0.1-0.3-0.2-0.20.20.7-0.2
Locomotion in novel chamber0.70.82.91.2-0.30.30.70.2-0.0-0.5-1.71.4
Locomotion in novel chamber post-restriction0.91.02.0-0.51.3-1.3-1.0-1.2-1.41.00.1-0.2
Progressive ratio1.31.52.4-1.40.9-0.9-1.2-1.3-1.51.30.9-1.5
Food seeking constrained by brief footshock0.70.92.2-1.50.4-0.4-1.0-0.3-0.50.81.3-1.4
Seeking ratio, punishment vs. effort0.40.41.20.5-0.60.60.50.91.1-0.7-0.20.5
Run reversals in cocaine runway, females1.01.01.81.3-0.80.81.10.80.6-1.0-0.71.3
Run reversals in cocaine runway, males1.81.72.2-1.41.2-1.2-1.5-1.4-1.21.50.9-1.3
Latency to leave start box in cocaine runway0.80.91.2-0.61.1-1.1-1.1-1.1-1.11.00.7-0.4
Latency to leave start box in cocaine runway, F0.90.91.8-0.31.3-1.3-0.9-1.2-1.31.0-0.30.1
Latency to leave start box in cocaine runway, M0.10.10.4-0.2-0.30.3-0.00.30.4-0.10.6-0.4
Cd content in liver2.62.93.7-1.91.5-1.5-1.9-1.8-1.91.90.9-1.7
Co content in liver0.20.30.80.50.9-0.90.1-0.2-0.10.1-0.10.7
Cu content in liver0.30.30.60.7-0.30.30.60.40.6-0.6-0.40.8
Fe content in liver0.10.10.20.3-0.20.20.50.50.3-0.4-0.20.3
K content in liver0.30.30.9-0.40.8-0.8-0.3-0.2-0.00.31.0-0.4
Mg content in liver0.30.31.4-0.60.1-0.1-0.20.10.30.01.2-0.7
Mn content in liver0.20.30.5-0.30.7-0.7-0.5-0.7-0.60.6-0.1-0.1
Na content in liver1.71.92.7-1.61.0-1.0-1.5-1.2-1.41.31.5-1.6
Rb content in liver1.51.83.2-1.61.3-1.3-1.3-0.9-0.81.21.8-1.6
Se content in liver1.11.41.7-1.21.0-1.0-1.3-1.3-1.31.31.0-1.2
Sr content in liver1.51.42.7-0.81.3-1.3-1.2-1.4-1.61.40.1-0.6
Zn content in liver1.61.73.5-0.61.9-1.9-1.2-1.5-1.51.4-0.0-0.3