Hub : Genes

Bicral

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016229 0.2 0.08 0.0e+00 0.16 0.17 0.17 0.17 3.7e-17 8.5e-19 1.9e-18 2.8e-18
2 Adipose mRNA stability ENSRNOG00000016229 0.26 0.1 0.0e+00 0.22 0.22 0.22 0.22 3.0e-24 3.7e-24 1.7e-23 1.8e-23
3 BLA gene expression ENSRNOG00000016229 0.61 0.15 0.0e+00 0.37 0.36 0.37 0.37 1.5e-20 2.8e-20 7.2e-21 5.2e-21
4 BLA mRNA stability ENSRNOG00000016229 0.2 0.11 6.6e-08 0.17 0.16 0.11 0.16 2.1e-09 9.7e-09 1.4e-06 6.5e-09
5 Brain gene expression ENSRNOG00000016229 0.44 0.14 0.0e+00 0.35 0.28 0.38 0.06 4.4e-34 3.9e-26 3.1e-37 2.5e-06
6 Brain mRNA stability ENSRNOG00000016229 0.38 0.12 0.0e+00 0.33 0.22 0.32 0.33 1.1e-31 1.5e-20 2.7e-30 9.7e-32
7 IL gene expression ENSRNOG00000016229 0.29 0.14 5.3e-05 0.22 0.17 0.17 0.22 7.0e-06 7.5e-05 6.7e-05 6.8e-06
8 IL mRNA stability ENSRNOG00000016229 0.36 0.15 1.3e-05 0.27 0.23 0.23 0.25 4.2e-07 3.4e-06 2.4e-06 1.1e-06
9 LHb gene expression ENSRNOG00000016229 0.29 0.15 4.0e-04 0.12 0.19 0.19 0.22 1.1e-03 2.5e-05 2.3e-05 5.8e-06
10 LHb mRNA stability ENSRNOG00000016229 0.25 0.15 1.4e-03 0.09 0.11 0.04 0.08 4.4e-03 1.8e-03 4.7e-02 7.2e-03
11 Liver gene expression ENSRNOG00000016229 0.22 0.1 0.0e+00 0.13 0.14 0.14 0.15 1.3e-14 2.5e-15 1.9e-15 3.5e-16
12 Liver intron excision ratio chr9:14162125:14171591 0.59 0.13 0.0e+00 0.2 0.19 0.19 0.2 1.2e-21 6.1e-21 1.5e-20 8.0e-22
13 NAcc mRNA stability ENSRNOG00000016229 0.22 0.12 7.4e-13 0.19 0.17 0.17 0.19 1.9e-14 6.9e-13 7.5e-13 8.2e-14
14 OFC gene expression ENSRNOG00000016229 0.23 0.14 1.4e-03 0.08 0.09 0.02 0.08 6.7e-03 3.1e-03 9.3e-02 5.2e-03
15 PL gene expression ENSRNOG00000016229 0.38 0.13 0.0e+00 0.41 0.4 0.4 0.4 2.5e-33 1.1e-32 1.1e-32 1.4e-32
16 PL mRNA stability ENSRNOG00000016229 0.18 0.09 3.6e-12 0.17 0.17 0.17 0.17 4.0e-13 6.1e-13 3.7e-13 6.0e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
BMI with tail1.75.415.92.6-0.23.5-0.23.90.63.4-0.02.0-1.02.6-0.1-0.24.03.40.3
BMI without tail4.59.429.23.2-0.84.7-0.65.10.34.6-0.42.3-1.93.4-0.6-0.65.44.50.0
Body weight1.04.314.12.1-0.73.0-0.73.50.03.0-0.51.5-1.52.1-0.6-0.73.83.0-0.3
Epididymis fat weight0.71.73.70.3-1.61.1-1.51.6-1.00.9-1.4-0.2-1.80.4-1.7-1.61.90.9-1.4
Glucose1.62.46.50.7-1.51.8-1.42.2-1.01.7-1.50.1-2.00.9-1.4-1.42.61.7-1.1
Heart weight0.50.81.90.21.3-0.41.1-0.61.1-0.41.00.41.40.21.01.2-1.0-0.31.0
Left kidney weight1.64.58.12.62.02.21.82.12.42.12.02.51.82.91.91.71.62.12.1
Right kidney weight1.54.26.62.42.21.92.01.62.41.82.12.32.02.62.22.01.11.82.1
Tail length0.61.96.21.3-0.72.1-0.42.3-0.12.0-0.40.9-1.11.4-0.6-0.42.51.9-0.3
Length with tail0.10.20.50.60.20.70.40.70.40.60.30.50.10.60.20.40.70.60.2
Length without tail0.81.85.4-1.01.0-1.80.8-2.10.4-1.90.7-0.51.3-1.10.80.9-2.3-1.80.3
Liver weight, left1.01.62.81.61.01.51.01.61.21.50.91.40.71.71.11.01.31.31.0
Liver weight, right0.30.41.30.8-0.01.0-0.01.20.20.9-0.00.6-0.20.9-0.2-0.01.20.9-0.0
Parametrial fat weight1.83.511.71.4-1.32.5-1.23.1-0.72.5-1.20.7-2.01.5-1.2-1.23.42.2-1.0
Retroperitoneal fat weight1.44.79.82.71.13.11.13.11.53.11.02.30.32.81.01.02.93.01.3
Intraocular pressure0.40.61.8-0.90.0-1.10.2-1.3-0.3-0.9-0.2-0.80.2-1.1-0.10.2-1.3-0.90.0
Extensor digitorum longus weight0.10.40.70.80.40.80.50.80.50.80.40.70.20.80.40.50.80.80.4
Soleus weight0.20.71.71.00.31.20.31.30.51.10.30.8-0.11.10.20.31.31.10.3
Tibialis anterior weight0.10.20.50.0-0.60.4-0.50.5-0.50.4-0.6-0.1-0.70.1-0.6-0.50.70.3-0.5
Tibia length1.33.79.22.30.32.80.43.00.92.90.41.8-0.32.40.40.43.02.80.8
Number of licking bursts2.63.16.9-0.8-2.40.4-2.40.8-2.10.4-2.3-1.2-2.6-0.7-2.4-2.41.40.4-2.1
Food consumed during 24 hour testing period0.80.91.61.20.61.20.61.30.81.30.71.10.41.20.70.61.11.20.7
Times rat made contact with spout2.22.55.00.0-1.91.1-1.91.6-1.61.2-2.0-0.6-2.20.1-1.9-1.92.01.2-1.6
Mean time between licks in bursts2.33.25.3-2.2-1.3-2.3-1.3-2.3-1.5-2.2-1.2-2.0-0.7-2.3-1.2-1.3-2.0-2.3-1.2
Mean num. licks in bursts0.50.71.40.61.10.11.1-0.11.00.11.00.71.20.61.11.1-0.40.01.0
Std. dev. time between licks in bursts0.60.72.1-0.60.4-1.10.3-1.40.3-1.10.8-0.20.9-0.80.50.3-1.5-1.10.4
Water consumed over 24 hours2.02.44.91.90.82.20.82.21.12.20.81.70.21.90.70.82.12.21.0
Indifference point 0 sec0.20.41.00.3-0.50.6-0.60.8-0.40.7-0.6-0.0-0.80.1-0.6-0.71.00.7-0.4
Indifference point AUC2.93.45.12.11.72.21.71.91.62.31.42.01.02.01.71.61.52.21.9
Indifference point function ln k0.20.30.8-0.5-0.2-0.9-0.2-0.8-0.2-0.8-0.0-0.50.3-0.6-0.1-0.2-0.8-0.9-0.2
Indifference point function log k0.20.30.8-0.5-0.2-0.9-0.2-0.8-0.2-0.8-0.0-0.50.3-0.6-0.1-0.2-0.8-0.9-0.2
Delay discounting total patch changes 0 sec0.30.51.40.4-0.50.8-0.71.0-0.40.9-0.50.1-0.80.2-0.6-0.71.20.9-0.4
Delay discounting total patch changes 12 sec2.22.95.12.01.32.11.41.91.52.11.31.90.82.01.31.31.72.31.6
Delay discounting total patch changes 18 sec1.82.35.11.81.02.11.11.91.12.20.81.60.41.61.01.01.82.31.2
Delay discounting total patch changes 24 sec0.81.02.31.20.71.40.41.20.71.50.51.10.20.90.50.51.31.50.7
Delay discounting total patch changes 6 sec0.91.43.91.30.21.90.11.90.31.80.11.1-0.51.30.10.22.01.80.3
Delay discounting time to switch 0 sec3.04.611.0-2.6-0.8-3.1-0.6-3.2-1.1-3.3-0.6-2.10.1-2.7-0.7-0.5-3.1-3.2-1.1
Delay discounting water rate 0 sec5.99.315.43.82.53.72.23.42.83.92.33.41.63.72.32.13.03.92.8
Delay discounting water rate 12 sec2.94.410.82.60.53.10.33.21.03.10.52.0-0.42.60.30.33.33.20.8
Delay discounting water rate 18 sec0.91.22.71.40.61.50.21.60.71.60.51.20.11.40.30.31.61.60.6
Delay discounting water rate 24 sec1.11.63.61.50.21.80.21.90.61.90.21.2-0.11.70.30.21.91.80.5
Delay discounting water rate 6 sec1.62.43.41.81.51.71.41.51.61.71.31.81.21.81.51.31.11.71.6
Locomotor activity0.71.13.00.4-1.01.2-1.01.5-0.71.0-1.1-0.1-1.40.6-1.2-0.91.71.0-1.0
Locomotor testing distance0.61.02.60.3-0.81.1-1.01.4-0.70.9-1.0-0.0-1.40.6-1.1-0.81.61.0-0.9
Locomotor testing rearing1.52.46.21.70.22.40.12.40.52.30.11.3-0.61.90.10.32.52.50.5
Light reinforcement 11.01.84.61.50.42.10.32.10.52.00.21.1-0.41.60.20.32.12.10.4
Light reinforcement 21.01.33.4-0.1-1.40.6-1.31.1-1.20.6-1.3-0.5-1.80.1-1.5-1.51.50.6-1.4
Reaction time number correct1.42.02.91.41.71.11.60.71.61.11.71.61.51.41.71.60.30.91.6
Reaction time mean minus median0.00.10.2-0.10.4-0.20.3-0.20.2-0.20.20.00.3-0.00.20.4-0.3-0.10.2
Reaction time mean minus median AUC0.40.51.1-1.0-0.2-1.0-0.4-1.0-0.6-1.1-0.4-0.8-0.2-0.9-0.4-0.3-0.9-0.9-0.5
Reaction time num false alarms0.20.31.0-0.50.5-0.80.3-1.00.1-0.80.3-0.30.4-0.50.30.4-1.0-0.60.2
Reaction time num false alarms AUC0.20.20.6-0.20.7-0.40.6-0.70.4-0.40.50.10.6-0.20.60.6-0.7-0.30.5
Reaction time trials correct on left1.42.02.91.41.71.11.60.71.61.11.71.61.51.41.71.60.30.91.6
Reaction time trials on left1.31.82.61.31.61.11.60.71.51.11.61.51.41.41.61.50.30.91.6
Reaction time mean2.33.14.3-2.1-1.6-1.8-1.7-1.5-1.8-1.9-1.7-2.1-1.5-2.1-1.9-1.6-1.1-1.6-1.9
Reaction time mean AUC2.93.95.3-2.3-1.9-1.9-1.9-1.6-2.1-2.0-2.0-2.3-1.8-2.2-2.1-1.9-1.1-1.7-2.2
Median of all reaction times2.73.64.8-2.2-1.9-1.8-1.9-1.4-2.1-1.9-2.0-2.2-1.8-2.2-2.1-1.8-1.0-1.7-2.1
Reaction time omissions0.20.30.6-0.0-0.50.3-0.60.5-0.50.3-0.7-0.2-0.80.2-0.7-0.50.70.4-0.6
Reaction time false alarm rate0.50.71.7-1.1-0.3-1.3-0.3-1.3-0.5-1.3-0.4-0.9-0.1-1.1-0.4-0.3-1.2-1.1-0.5
Reaction time premature initiation rate0.30.41.20.5-0.10.7-0.20.9-0.20.9-0.30.3-0.60.3-0.4-0.41.11.0-0.2
Reaction time premature initiations0.91.32.81.40.91.50.71.50.81.60.71.30.31.30.60.61.41.70.9
Std. dev. reaction times0.81.01.7-1.3-0.7-1.1-0.9-1.0-1.0-1.3-0.9-1.2-0.8-1.1-1.0-0.8-0.8-1.0-1.1
Reaction time trials completed1.31.82.61.31.61.11.60.71.51.11.61.51.41.41.61.50.30.91.6
Reaction time trials AUC1.31.92.61.41.61.21.60.81.51.31.61.61.41.41.61.50.51.01.6
Social response proportion0.30.30.9-0.40.2-0.80.2-0.80.3-0.90.4-0.10.6-0.30.20.3-0.9-0.90.1
Social responses0.71.02.1-0.21.0-0.91.0-1.20.9-1.01.20.31.4-0.40.91.0-1.4-1.00.8
Social time4.05.39.41.92.91.02.90.42.91.03.02.43.01.82.93.1-0.30.92.9
Conditioned locomotion1.92.24.40.82.00.02.0-0.41.90.02.01.32.10.72.12.0-0.80.12.0
Cocaine response after cond. corrected0.20.20.4-0.5-0.0-0.6-0.1-0.6-0.2-0.6-0.1-0.40.0-0.6-0.1-0.1-0.6-0.6-0.2
Cocaine response after cond. not corrected0.10.20.5-0.40.3-0.50.3-0.60.0-0.50.1-0.30.3-0.40.20.3-0.7-0.50.1
Cocaine response before conditioning0.50.60.80.90.80.70.80.60.80.80.70.90.60.90.80.80.50.70.8
Saline control response0.20.30.50.60.70.50.70.40.70.40.60.60.50.60.60.70.20.40.6
Condit. Reinf. active minus inactive responses0.81.01.6-1.0-1.1-0.7-1.1-0.5-1.2-0.7-1.3-1.1-1.0-0.9-1.2-1.1-0.3-0.7-1.2
Condit. Reinf. active-inactive response ratio2.02.04.3-1.2-1.7-0.4-1.8-0.0-1.8-0.4-2.1-1.5-1.9-0.9-1.9-1.80.3-0.4-1.9
Condit. Reinf. active responses0.10.20.3-0.5-0.5-0.3-0.5-0.3-0.5-0.3-0.6-0.5-0.4-0.4-0.5-0.5-0.2-0.4-0.5
Condit. Reinf. inactive responses0.50.61.10.90.80.60.90.31.00.51.01.01.00.80.90.90.20.51.0
Condit. Reinf. lever presses0.40.51.2-0.3-1.10.1-1.00.3-0.90.1-0.9-0.5-1.0-0.2-1.1-1.00.50.1-1.0
Condit. Reinf. lever reinforcers received0.10.20.3-0.4-0.4-0.3-0.4-0.3-0.5-0.4-0.5-0.4-0.3-0.4-0.5-0.4-0.2-0.4-0.5
Pavlov. Cond. lever latency0.91.22.4-0.11.4-0.91.3-1.21.0-0.81.20.21.6-0.31.41.3-1.5-0.81.2
Pavlov. Cond. magazine entry latency0.50.61.80.5-0.71.0-0.61.1-0.30.9-0.40.3-0.90.5-0.7-0.61.31.0-0.4
Pavlov. Cond. change in total contacts0.81.22.30.1-1.30.9-1.31.2-0.90.8-1.1-0.2-1.50.1-1.4-1.31.50.9-1.1
Pavlov. Cond. index score1.31.75.00.7-1.21.6-1.11.9-0.71.5-0.90.3-1.60.8-1.2-1.12.21.6-0.8
Pavlov. Cond. latency score1.41.85.10.7-1.31.6-1.21.9-0.81.5-1.00.3-1.70.8-1.3-1.22.31.6-0.9
Pavlov. Cond. lever contacts0.91.23.00.4-1.21.2-1.21.4-0.71.0-1.00.1-1.40.6-1.3-1.21.71.1-1.0
Pavlov. Cond. magazine entry number0.20.31.0-0.50.2-0.80.2-0.8-0.0-0.7-0.0-0.50.4-0.50.30.2-1.0-0.80.1
Pavlov. Cond. intertrial magazine entries0.00.00.00.0-0.00.00.00.1-0.10.1-0.1-0.00.00.10.10.00.0-0.1-0.0
Pavlov. Cond. lever-magazine prob. diff.1.31.74.70.6-1.31.5-1.21.8-0.81.4-1.00.2-1.60.7-1.3-1.22.21.5-1.0
Pavlov. Cond. response bias0.30.40.90.1-0.80.6-0.80.7-0.50.4-0.50.0-0.90.3-0.9-0.81.00.5-0.7
Conditioned reinforcement - actives1.61.62.90.91.60.51.6-0.01.50.51.51.21.70.91.71.6-0.40.51.6
Conditioned reinforcement - inactives1.21.42.41.50.81.50.81.31.01.50.81.40.61.41.00.81.31.61.0
Conditioned locomotion0.00.00.10.20.20.10.30.00.20.20.10.20.20.10.20.30.10.10.1
Intermittent access intake day 1-15 change1.01.01.51.21.01.00.90.91.20.91.01.20.91.10.90.90.61.01.0
Intermittent access intake escalation0.20.20.50.60.50.40.40.40.70.30.60.70.50.60.40.40.20.40.5
Intermittent access intake escalation 21.11.11.61.31.11.11.01.01.21.01.01.20.91.21.01.00.71.11.1
Intermitt. access day 1 inactive lever presses0.40.41.50.7-0.30.9-0.31.0-0.10.9-0.30.5-0.50.3-0.2-0.31.21.0-0.2
Intermitt. access day 15 inactive lever presses0.80.92.61.1-0.31.3-0.31.60.31.2-0.20.7-0.41.3-0.2-0.31.61.2-0.1
Intermitt. access escalation Index0.30.20.5-0.6-0.5-0.5-0.5-0.4-0.5-0.5-0.4-0.5-0.4-0.7-0.4-0.5-0.3-0.5-0.4
Intermittent access day 1 total infusions0.60.71.6-0.6-1.0-0.2-1.0-0.1-1.1-0.1-1.0-0.7-1.3-0.8-1.0-1.00.3-0.1-1.1
Intermittent access day 15 total infusions0.10.20.5-0.2-0.5-0.0-0.50.0-0.50.1-0.5-0.2-0.7-0.4-0.5-0.50.30.1-0.5
Intermittent access terminal intake (last 3 days)0.20.20.6-0.4-0.5-0.3-0.5-0.3-0.6-0.2-0.6-0.5-0.7-0.7-0.6-0.50.1-0.1-0.6
Intermittent access total infusions0.60.61.0-0.8-0.8-0.6-0.8-0.5-1.0-0.5-0.8-0.8-1.0-1.0-0.8-0.8-0.2-0.4-0.9
Intermittent access day 1 locomotion1.21.22.2-1.1-1.2-0.7-1.2-0.7-1.5-0.6-1.3-1.2-1.4-1.3-1.2-1.2-0.1-0.6-1.4
Intermittent access day 15 total locomotion0.10.10.30.2-0.10.4-0.10.4-0.10.4-0.20.1-0.30.2-0.2-0.10.60.4-0.2
Intermittent access total locomotion1.21.42.1-1.3-1.1-1.0-1.2-0.9-1.4-1.0-1.3-1.4-1.2-1.4-1.3-1.2-0.5-0.9-1.4
Intermittent access standard deviation1.61.74.4-1.5-0.2-2.0-0.2-2.1-0.4-2.1-0.1-1.20.4-1.5-0.3-0.2-2.1-2.0-0.5
Cocaine induced anxiety0.20.30.6-0.3-0.8-0.1-0.70.1-0.5-0.2-0.8-0.5-0.6-0.0-0.7-0.70.2-0.3-0.7
Post-drug Anxiety0.50.50.9-0.7-0.9-0.5-0.9-0.3-0.7-0.7-0.8-0.8-0.6-0.4-0.9-0.9-0.2-0.7-1.0
Baseline Anxiety0.10.10.2-0.10.3-0.20.3-0.40.2-0.30.4-0.00.4-0.20.30.3-0.4-0.20.3
Lifetime Intake0.30.30.8-0.7-0.4-0.7-0.4-0.8-0.6-0.7-0.4-0.6-0.4-0.9-0.3-0.4-0.5-0.6-0.5
Incentive Sensitization - Responses0.90.91.81.20.41.30.31.30.61.40.51.10.01.10.50.31.31.30.5
Incentive Sensitization - Breakpoint0.90.91.91.20.41.30.41.30.61.40.51.10.01.10.50.41.31.30.5
Progressive ratio test 1 active lever presses1.01.12.6-0.7-1.3-0.2-1.3-0.1-1.4-0.2-1.3-0.9-1.6-1.0-1.4-1.30.5-0.1-1.3
Progressive ratio test 1 breakpoint0.60.61.6-0.4-0.9-0.1-0.90.0-1.10.1-0.9-0.6-1.3-0.9-1.0-0.90.50.1-0.9
Progressive ratio test 1 inactive lever presses0.40.41.10.80.10.90.10.80.11.00.10.7-0.20.30.10.11.01.10.2
Progressive ratio test 2 active lever presses0.50.51.50.80.21.10.20.90.21.20.20.7-0.30.70.20.21.11.20.3
Progressive ratio test 2 breakpoint0.70.82.21.00.21.40.21.20.21.50.10.8-0.40.80.10.21.41.50.3
Progressive ratio test 2 inactive lever presses0.20.30.70.70.10.80.10.70.30.80.20.6-0.10.50.10.10.80.90.3
Total sessions with >9 infusions0.10.10.20.20.40.10.5-0.10.30.20.40.30.20.10.40.5-0.10.20.4
Short access day 1 total inactive lever presses0.70.81.41.20.70.90.70.91.00.90.91.10.81.10.90.70.60.80.9
Short access day 10 total inactive lever presses1.11.22.31.40.61.40.61.50.91.50.61.30.41.30.70.61.31.50.8
Short access day 1 total infusions0.20.20.50.10.5-0.20.5-0.40.5-0.10.70.30.70.10.60.5-0.5-0.10.6
Short access day 10 total infusions0.91.02.0-1.2-0.8-1.0-0.9-1.0-1.2-0.9-0.9-1.1-1.0-1.4-1.0-0.9-0.5-0.8-1.1
Short access total infusions0.50.51.3-0.9-0.2-1.0-0.2-1.1-0.5-0.9-0.2-0.7-0.2-1.1-0.2-0.2-0.9-0.9-0.3
Short access day 1 locomotion0.20.30.8-0.50.3-0.80.3-0.9-0.1-0.60.2-0.40.3-0.70.10.3-0.9-0.60.1
Short access day 10 total locomotion2.52.75.2-2.0-0.7-2.3-0.8-2.3-1.2-2.3-0.9-1.8-0.4-2.2-0.9-0.8-2.0-2.2-1.2
Short access total locomotion0.90.92.7-0.90.4-1.40.4-1.6-0.1-1.20.3-0.60.6-1.30.40.4-1.6-1.20.1
Compulsive drug intake0.80.81.30.91.00.71.00.51.00.80.90.90.90.91.11.00.20.71.1
One hour access (0.3 mA shock)1.01.22.20.91.40.51.40.21.30.71.31.11.30.71.51.4-0.10.81.5
One hour access (shock baseline)0.10.10.3-0.1-0.30.0-0.40.0-0.40.1-0.4-0.1-0.5-0.4-0.5-0.40.30.2-0.4
Number of responses in last shaping day0.40.40.70.80.60.70.60.70.60.80.60.80.40.60.60.60.60.80.7
Context. condit. distance diff. score0.00.00.10.1-0.00.3-0.00.3-0.10.2-0.20.1-0.30.1-0.2-0.00.40.4-0.2
Locomotion velocity, session 12.12.33.21.81.31.71.41.61.51.61.31.80.91.81.41.41.31.61.5
Locomotion distance, session 11.01.33.71.30.01.70.11.90.31.6-0.01.0-0.51.5-0.00.11.91.70.1
Locomotion velocity, session 24.14.810.92.61.03.20.93.31.33.00.82.3-0.02.90.80.93.23.01.1
Locomotion distance, session 20.81.22.81.30.41.60.41.70.51.60.31.1-0.11.40.40.41.71.60.5
Locomotion velocity, session 31.92.23.21.81.31.61.41.51.51.61.31.71.01.71.41.41.31.61.5
Locomotion distance, session 31.01.12.20.71.30.11.4-0.21.30.11.40.91.50.71.41.4-0.40.11.3
Stereotopy head waving bouts, day 30.40.51.20.3-0.70.8-0.60.9-0.50.8-0.60.0-0.90.3-0.6-0.61.10.8-0.4
Stereotopy head waving duration, day 30.70.92.71.0-0.21.4-0.11.6-0.01.5-0.20.7-0.60.9-0.1-0.11.61.50.1
Locomotion velocity, session 71.82.02.81.61.51.41.41.21.51.41.51.71.11.51.41.41.01.51.6
Locomotion distance, session 71.01.31.71.31.31.11.20.91.21.11.11.30.91.21.31.20.71.21.3
Stereotopy head waving bouts, day 70.10.10.3-0.1-0.40.1-0.40.2-0.50.1-0.3-0.2-0.5-0.2-0.5-0.40.30.2-0.3
Stereotopy head waving duration, day 70.60.71.2-1.0-0.8-0.8-0.9-0.7-1.0-0.8-0.7-0.9-0.7-1.1-0.9-0.9-0.5-0.7-0.8
Locomotion velocity, session 80.50.61.20.90.61.10.51.10.51.00.20.80.01.00.30.51.01.00.3
Locomotion distance, session 80.40.61.80.90.21.20.21.30.21.10.00.7-0.40.90.10.21.41.30.1
Degree of sensitization distance0.80.82.31.00.21.30.11.40.31.40.10.8-0.40.90.20.11.51.50.3
Degree of sensitization stereotypy0.30.40.9-0.8-0.1-0.9-0.2-0.9-0.4-0.9-0.1-0.6-0.1-0.9-0.3-0.2-0.8-0.7-0.2
Condit. Reinf. active minus inactive responses0.50.61.70.5-0.51.1-0.41.2-0.31.1-0.50.3-0.80.6-0.4-0.41.31.0-0.3
Condit. Reinf. active-inactive response ratio0.30.40.9-0.4-0.8-0.0-0.80.1-0.8-0.0-0.9-0.5-0.9-0.3-0.8-0.80.3-0.1-0.8
Condit. Reinf. active responses0.91.13.50.9-0.51.5-0.51.7-0.21.5-0.50.6-1.01.0-0.5-0.51.91.5-0.3
Condit. Reinf. inactive responses0.70.82.70.8-0.51.3-0.51.5-0.21.2-0.40.5-0.80.8-0.6-0.51.61.3-0.3
Incentive salience index mean1.31.63.81.50.31.90.32.00.61.90.31.2-0.21.60.30.31.91.90.5
Condit. Reinf. lever presses2.23.07.32.00.32.60.32.70.72.50.31.7-0.32.30.20.32.72.60.5
Time in familiar zone, hab. session 12.82.73.91.91.51.71.51.51.71.71.72.01.11.91.51.51.31.71.7
Time in novel zone, hab. session 11.81.72.9-1.7-0.9-1.6-0.9-1.5-1.4-1.4-1.2-1.6-0.7-1.7-0.9-0.9-1.4-1.5-1.1
Total zone transitions, hab. session 11.52.16.51.4-0.32.2-0.32.4-0.12.1-0.31.0-1.11.7-0.4-0.32.62.2-0.1
Total locomotion distance, hab. session 12.33.38.52.10.32.80.32.90.62.70.31.7-0.42.40.20.32.92.70.5
Locomotion velocity, hab. session 12.33.48.12.20.42.80.42.90.82.60.41.8-0.32.50.40.42.82.70.6
Time in familiar zone, hab. session 21.11.13.0-1.3-0.1-1.6-0.0-1.7-0.3-1.6-0.1-0.90.2-1.5-0.1-0.0-1.7-1.5-0.2
Time in novel zone, hab. session 20.30.30.70.70.20.80.20.80.20.80.10.50.00.80.30.20.70.70.3
Total zone transitions, hab. session 21.82.35.1-0.5-2.00.5-2.00.9-1.80.4-2.1-0.9-2.3-0.2-2.1-2.01.40.5-1.9
Total locomotion distance, hab. session 21.21.63.10.2-1.51.1-1.41.4-1.21.0-1.4-0.3-1.70.4-1.5-1.41.81.0-1.2
Locomotion velocity, hab. session 21.01.42.70.1-1.50.9-1.51.2-1.20.8-1.4-0.4-1.60.3-1.5-1.51.50.8-1.3
Novel to familiar place preference ratio0.00.00.10.2-0.00.3-0.10.30.10.3-0.00.1-0.10.2-0.1-0.10.30.30.0
Novelty place preference0.00.10.10.30.20.20.20.20.30.20.30.30.20.20.20.20.20.30.3
Time in novel zone, NPP test0.00.00.10.20.20.10.10.10.20.20.20.20.10.10.20.10.10.20.3
Total zone transitions, NPP test2.13.19.91.4-0.92.5-0.92.9-0.52.4-1.00.8-1.71.6-1.0-0.93.22.4-0.7
Total locomotion distance, NPP test1.92.68.01.2-1.22.1-1.22.5-0.72.0-1.10.5-1.71.3-1.3-1.22.82.0-0.9
Locomotion velocity, NPP test2.02.99.01.2-1.32.3-1.22.7-0.72.1-1.20.5-1.81.4-1.4-1.23.02.1-1.0
Pavlov. Cond. lever latency3.24.07.1-2.5-1.3-2.6-1.3-2.6-1.7-2.6-1.2-2.3-0.7-2.6-1.2-1.3-2.4-2.7-1.4
Pavlov. Cond. magazine entry latency2.93.75.62.31.72.11.71.92.02.11.82.21.32.41.71.71.62.11.9
Pavlov. Cond. change in total contacts2.02.14.11.80.72.00.72.01.02.00.71.60.32.00.80.71.92.00.9
Pavlov. Cond. index score4.25.38.62.91.72.91.62.82.02.91.72.60.92.91.61.62.62.91.8
Pavlov. Cond. latency score4.45.68.72.91.92.81.92.62.32.81.92.71.33.01.81.92.32.82.1
Pavlov. Cond. lever contacts3.64.27.92.61.12.81.12.81.62.81.22.30.52.71.01.12.72.81.3
Pavlov. Cond. magazine entry number3.03.76.2-2.4-1.3-2.4-1.3-2.4-1.7-2.4-1.4-2.2-0.8-2.5-1.3-1.3-2.1-2.4-1.6
Pavlov. Cond. intertrial magazine entries0.50.51.4-0.9-0.1-1.1-0.1-1.2-0.3-1.1-0.2-0.70.2-0.9-0.1-0.1-1.2-1.1-0.3
Pavlov. Cond. lever-magazine prob. diff.4.05.08.12.81.62.81.62.72.02.81.62.61.02.81.51.62.52.81.8
Pavlov. Cond. response bias3.74.69.02.71.03.01.03.01.53.01.12.30.32.80.91.02.92.91.3
Bone: apparent density1.01.62.4-1.5-1.2-1.4-1.0-1.3-1.2-1.4-1.1-1.4-0.8-1.6-1.2-1.0-1.1-1.4-1.3
Bone surface1.01.73.7-1.6-0.6-1.9-0.5-1.9-0.8-1.9-0.6-1.3-0.1-1.6-0.6-0.5-1.8-1.9-0.9
Bone volume0.50.91.7-1.2-0.6-1.3-0.5-1.3-0.7-1.3-0.5-1.0-0.2-1.2-0.6-0.5-1.2-1.2-0.7
Bone: connectivity density2.64.05.7-2.4-1.9-2.2-1.7-2.1-2.0-2.2-1.8-2.3-1.2-2.4-1.8-1.7-1.7-2.3-2.0
Bone: cortical apparent density0.40.51.00.10.9-0.30.9-0.50.8-0.30.90.41.0-0.00.90.9-0.7-0.30.8
Bone: cortical area2.23.34.72.21.72.01.61.91.91.91.72.11.12.11.61.61.62.11.7
Bone: cortical porosity0.10.10.3-0.2-0.60.0-0.30.1-0.4-0.0-0.4-0.3-0.4-0.1-0.4-0.30.2-0.1-0.4
Bone: cortical porosity0.10.10.10.40.00.30.20.30.20.30.20.30.10.30.20.20.30.20.2
Bone: cortical thickness2.54.15.82.41.82.31.82.22.02.21.82.31.12.41.71.81.92.41.9
Bone: cortical thickness0.10.10.1-0.4-0.2-0.3-0.3-0.3-0.3-0.4-0.2-0.4-0.3-0.4-0.3-0.3-0.2-0.2-0.3
Bone: cortical tissue density0.30.40.80.00.8-0.30.8-0.50.6-0.40.80.30.9-0.10.80.8-0.7-0.40.7
Bone: elastic displacement0.10.10.3-0.10.4-0.20.5-0.40.2-0.30.30.10.4-0.10.30.5-0.5-0.30.3
Bone: elastic work0.00.00.1-0.1-0.10.1-0.00.1-0.1-0.0-0.0-0.0-0.2-0.1-0.2-0.00.10.1-0.1
Bone: endosteal estimation0.30.61.4-0.9-0.2-1.1-0.4-1.2-0.4-1.1-0.2-0.80.1-0.9-0.3-0.4-1.1-1.1-0.4
Bone: endosteal perimeter0.00.00.00.1-0.00.0-0.10.00.1-0.00.10.00.10.10.0-0.10.00.10.1
Bone: final force0.30.51.20.90.31.00.41.00.50.90.50.80.10.80.30.41.01.10.4
Bone: final moment0.71.22.01.40.81.30.91.31.11.31.01.30.51.30.80.91.21.40.9
Bone: marrow area0.20.51.3-0.8-0.1-1.1-0.3-1.2-0.2-1.1-0.1-0.70.3-0.8-0.1-0.3-1.1-1.0-0.3
Bone: maximum diameter1.11.92.81.71.41.41.21.31.51.41.41.61.01.71.31.21.11.51.4
Bone: maximum force0.00.10.2-0.2-0.4-0.1-0.3-0.0-0.3-0.2-0.2-0.2-0.3-0.3-0.4-0.30.1-0.0-0.4
Bone: maximum moment0.00.00.10.20.10.20.20.20.20.10.30.20.10.10.10.20.20.20.1
Bone: minimum diameter0.30.61.01.00.50.90.40.90.70.90.60.90.30.90.50.40.91.00.6
Bone: periosteal estimation0.40.81.21.10.90.80.80.71.10.81.01.00.81.00.90.80.60.91.0
Bone: periosteal perimeter0.61.12.21.30.61.30.51.30.91.20.81.10.31.30.60.51.31.50.8
Bone: post-yield work0.50.71.1-0.8-1.0-0.7-0.9-0.5-0.9-0.6-0.9-0.9-0.7-0.8-1.0-0.9-0.3-0.7-1.0
Bone: stiffness0.00.00.1-0.2-0.2-0.3-0.2-0.2-0.2-0.3-0.1-0.2-0.1-0.3-0.2-0.2-0.1-0.2-0.3
Bone: tissue strength0.20.20.40.30.50.10.60.00.50.10.50.30.50.20.50.6-0.10.10.5
Bone: trabecular number0.30.51.2-0.9-0.4-1.0-0.2-1.1-0.4-1.1-0.3-0.7-0.1-0.9-0.4-0.2-1.0-1.1-0.5
Bone: trabecular spacing1.01.32.21.40.91.40.81.41.01.40.91.30.61.51.00.81.21.41.1
Bone: trabecular thickness1.11.32.3-1.4-0.8-1.5-0.8-1.5-0.9-1.5-0.7-1.3-0.4-1.5-0.8-0.8-1.3-1.4-0.9
Bone: trabecular tissue density1.62.34.01.51.81.01.80.71.81.11.81.61.61.32.01.80.31.12.0
Breakpoint value in progressive ratio session0.50.51.10.61.00.70.80.40.80.60.50.70.61.00.60.80.20.80.7
Distance traveled before self-admin0.40.40.70.80.60.70.40.70.70.70.50.70.40.80.70.40.60.80.5
Distance traveled after self-admin1.11.24.00.9-0.31.5-0.51.7-0.21.6-0.80.4-1.10.9-0.5-0.52.01.4-0.6
Delta time in closed arm before/after self-admin0.70.61.2-0.7-1.0-0.6-1.0-0.3-0.9-0.6-0.8-0.8-0.9-0.8-1.1-1.0-0.0-0.5-1.0
Delta time in open arm before/after self-admin0.10.10.3-0.10.3-0.20.5-0.40.2-0.10.2-0.00.4-0.20.60.4-0.5-0.10.4
Diff in mean of infusions in LGA sessions1.21.32.41.31.01.40.91.21.11.40.81.30.61.50.90.91.01.61.1
Extinction: sum of active levers before priming0.00.00.20.10.50.10.1-0.0-0.10.30.00.2-0.0-0.00.10.10.10.50.2
Active lever presses in extinction session 61.61.52.71.31.61.31.31.01.31.30.81.31.01.41.31.30.71.31.1
Delta distance traveled before/after self-admin1.71.94.50.0-1.50.9-1.51.3-1.41.0-1.8-0.6-2.1-0.1-1.6-1.51.80.8-1.6
Delta ambulatory time before/after self-admin1.51.63.80.0-1.50.8-1.41.2-1.31.0-1.7-0.5-2.0-0.2-1.5-1.41.60.7-1.4
Time in closed arm before self-admin1.01.11.9-1.2-0.9-1.1-1.0-1.0-1.0-1.1-0.9-1.3-0.7-1.4-0.9-1.0-0.8-1.1-1.0
Time in closed arm after self-admin3.03.14.2-1.8-1.8-1.7-1.9-1.3-1.9-1.6-1.8-2.0-1.6-2.0-2.0-1.9-0.8-1.6-2.0
Time in open arm before self-admin2.82.95.42.10.82.21.02.31.32.31.12.00.42.21.01.02.22.31.2
Time in open arm after self-admin1.51.72.81.51.01.61.31.31.21.71.01.40.71.41.31.21.21.61.3
Sum of active levers in priming session hrs 5-62.42.44.11.42.00.71.80.41.80.81.91.72.01.42.01.8-0.10.82.0
Time to tail flick, vehicle, before self-admin0.20.20.50.20.70.00.5-0.10.6-0.10.70.30.70.20.20.5-0.3-0.10.4
Time to tail flick, vehicle, after self-admin1.92.05.0-1.7-0.9-2.0-0.6-1.9-0.8-2.2-0.6-1.50.0-1.7-0.8-0.5-1.9-2.2-1.0
Time to tail flick, test, before self-admin2.42.46.40.51.8-0.51.9-0.81.9-0.42.11.02.50.42.11.9-1.5-0.62.0
Time to tail flick, test, after self-admin0.10.10.4-0.00.4-0.30.4-0.30.4-0.30.50.00.7-0.10.40.4-0.5-0.20.5
Delta time to tail flick, vehicle, before/after SA0.50.41.0-0.8-0.6-0.9-0.2-0.8-0.5-1.0-0.5-0.7-0.0-0.8-0.2-0.2-0.9-1.0-0.5
Delta time to tail flick, test, before/after SA2.92.64.6-1.3-2.2-0.7-2.0-0.2-2.0-0.8-1.9-1.6-2.1-1.3-2.1-2.00.3-0.6-2.1
Ambulatory time before self-admin0.80.81.41.01.10.60.80.51.20.61.11.01.01.01.10.90.30.71.0
Ambulatory time after self-admin1.01.13.80.9-0.51.3-0.61.7-0.21.5-0.80.4-1.10.7-0.5-0.71.91.3-0.6
Total heroin consumption0.00.00.1-0.10.00.00.00.1-0.10.2-0.3-0.2-0.3-0.0-0.2-0.00.20.1-0.3
Area under the delay curve2.52.76.7-0.11.6-1.31.9-1.81.5-1.21.90.52.6-0.41.91.8-2.4-1.21.8
Delay disc. indifference point, 0s delay0.50.51.6-0.60.6-0.90.5-1.2-0.2-0.60.0-0.50.5-1.00.60.6-1.3-0.50.4
Delay disc. indifference point, 16s delay3.33.48.3-0.41.7-1.71.9-2.21.6-1.72.00.32.9-0.51.91.8-2.9-1.81.8
Delay disc. indifference point, 2s delay0.91.02.3-0.21.0-0.71.2-1.20.7-0.51.00.21.5-0.51.21.2-1.5-0.71.1
Delay disc. indifference point, 24s delay0.30.31.0-0.50.2-0.80.2-0.80.1-0.80.2-0.30.5-0.30.00.2-1.0-0.90.1
Delay disc. indifference point, 4s delay3.94.08.41.52.40.42.5-0.12.50.62.71.92.91.32.82.5-0.70.62.8
Delay disc. indifference point, 8s delay1.81.95.10.21.5-0.81.7-1.21.5-0.71.70.72.30.11.71.6-1.7-0.71.7
Delay discount exponential model param2.62.77.10.0-1.71.2-1.91.6-1.61.1-2.0-0.6-2.70.2-2.0-1.92.31.1-1.9
Delay discount hyperbolic model param2.42.66.7-0.1-1.71.0-1.91.5-1.60.9-1.9-0.7-2.60.2-2.0-1.92.11.0-1.9
Fecal boli incidents, locomotor time 11.92.03.91.32.00.81.70.51.71.01.61.41.71.21.81.70.01.01.8
Change in fecal boli incidents, locomotor task0.40.30.60.50.50.30.70.20.70.30.80.60.70.50.60.80.00.30.8
Time >=10cm from walls, locomotor time 10.50.51.50.80.60.80.40.60.51.00.40.70.20.60.30.40.71.20.7
Bouts of movement, locomotor time 11.61.83.0-1.6-1.1-1.4-1.1-1.3-1.5-1.3-1.5-1.7-1.3-1.6-1.2-1.2-0.9-1.1-1.4
Total resting periods, locomotor time 11.31.52.5-1.3-1.1-0.9-1.2-0.8-1.5-0.8-1.6-1.5-1.5-1.4-1.3-1.2-0.3-0.6-1.4
Rest time, locomotor task time 10.20.30.8-0.30.7-0.70.3-0.90.2-0.40.2-0.20.5-0.50.40.4-0.9-0.20.5
Distance moved, locomotor task time 10.10.10.5-0.1-0.7-0.1-0.30.1-0.3-0.2-0.1-0.1-0.3-0.1-0.3-0.60.1-0.4-0.3
Vertical activity count, locomotor time 10.20.20.4-0.10.1-0.20.6-0.30.4-0.40.50.10.60.10.40.4-0.6-0.50.4
Time >=10cm from walls, locomotor time 21.11.12.31.30.61.30.61.21.01.40.71.20.51.50.90.71.11.30.9
Bouts of movement, locomotor time 20.10.10.30.1-0.60.4-0.30.4-0.10.2-0.30.0-0.50.3-0.5-0.30.5-0.0-0.4
Total resting periods, locomotor time 20.20.20.5-0.4-0.7-0.1-0.4-0.1-0.4-0.2-0.5-0.4-0.5-0.2-0.7-0.50.0-0.4-0.6
Rest time, locomotor task time 20.70.82.0-1.3-0.1-1.2-0.4-1.4-0.7-1.1-0.6-1.1-0.4-1.1-0.7-0.4-1.2-0.7-0.4
Distance moved, locomotor task time 20.30.31.20.4-1.10.5-0.60.9-0.30.6-0.30.1-0.70.2-0.2-0.61.00.1-0.5
Vertical activity count, locomotor time 20.30.40.90.60.40.30.70.40.80.30.70.60.90.70.90.60.00.10.6
Weight adjusted by age0.20.21.00.6-0.30.70.10.90.30.60.20.50.01.00.10.10.70.0-0.0
Seeking ratio, delayed vs. immediate footshock0.91.13.1-1.20.1-1.50.1-1.7-0.4-1.4-0.1-0.90.4-1.30.10.1-1.8-1.5-0.3
Locomotion in novel chamber0.30.41.00.10.7-0.30.8-0.50.7-0.30.80.31.0-0.10.70.8-0.7-0.40.7
Locomotion in novel chamber post-restriction1.92.34.81.22.00.41.70.11.90.42.11.42.21.12.01.7-0.50.52.0
Progressive ratio0.20.30.70.10.8-0.30.7-0.40.6-0.20.60.30.8-0.00.60.7-0.6-0.20.6
Food seeking constrained by brief footshock0.10.10.2-0.3-0.3-0.1-0.4-0.1-0.4-0.2-0.4-0.3-0.4-0.4-0.4-0.40.1-0.0-0.5
Seeking ratio, punishment vs. effort0.20.20.50.1-0.60.5-0.50.6-0.40.4-0.4-0.1-0.70.2-0.4-0.50.70.3-0.4
Run reversals in cocaine runway, females1.41.42.51.50.91.50.91.41.11.50.81.40.51.50.80.91.31.61.0
Run reversals in cocaine runway, males0.10.10.50.30.40.30.20.20.20.30.10.30.10.30.30.20.30.70.4
Latency to leave start box in cocaine runway0.91.02.51.20.11.50.41.50.51.60.31.0-0.21.00.40.41.61.30.4
Latency to leave start box in cocaine runway, F0.10.10.2-0.1-0.30.1-0.30.1-0.30.1-0.2-0.2-0.5-0.2-0.2-0.30.3-0.0-0.3
Latency to leave start box in cocaine runway, M3.13.06.82.10.52.60.82.51.02.60.61.8-0.11.90.80.82.52.30.9
Cd content in liver0.40.40.9-0.00.7-0.50.7-0.70.5-0.40.70.20.9-0.20.80.7-0.9-0.50.6
Co content in liver0.10.10.2-0.3-0.5-0.2-0.4-0.1-0.4-0.1-0.4-0.4-0.4-0.3-0.3-0.4-0.0-0.2-0.2
Cu content in liver1.11.42.60.91.60.31.50.11.40.41.51.11.50.81.61.5-0.30.41.6
Fe content in liver0.20.30.60.10.8-0.20.8-0.50.6-0.30.80.30.70.00.60.8-0.5-0.20.6
K content in liver3.23.24.4-2.1-1.7-1.8-1.7-1.6-1.8-1.9-1.7-2.1-1.3-2.0-1.7-1.7-1.3-1.8-1.7
Mg content in liver0.60.61.7-0.50.6-0.90.6-1.20.5-1.00.7-0.10.9-0.50.60.6-1.3-1.00.6
Mn content in liver1.21.32.8-0.8-1.7-0.2-1.70.1-1.5-0.1-1.6-1.1-1.6-0.7-1.4-1.70.4-0.2-1.1
Na content in liver0.50.50.80.70.70.70.70.60.80.60.90.80.50.80.70.70.50.70.9
Rb content in liver2.12.66.2-0.51.6-1.61.7-2.11.3-1.71.70.12.2-0.71.61.7-2.5-1.71.2
Se content in liver0.20.20.40.50.30.50.30.50.40.60.30.40.10.50.40.30.50.60.6
Sr content in liver0.30.30.80.60.00.80.00.90.10.90.00.5-0.20.60.00.00.90.80.1
Zn content in liver3.13.47.80.82.5-0.42.5-1.02.2-0.42.51.32.80.52.52.5-1.5-0.42.2