Hub : Genes

Rpp40

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016226 0.04 0.03 9.2e-07 0.05 0.05 0.04 0.04 5.7e-06 6.6e-06 1.5e-05 9.5e-06
2 Adipose isoform ratio ENSRNOT00000068617 0.02 0.02 5.9e-03 -0 0 0 -0 6.6e-01 1.4e-01 1.4e-01 7.6e-01
3 BLA gene expression ENSRNOG00000016226 0.42 0.15 6.1e-05 0.03 0.1 0.06 0.05 6.6e-03 4.0e-06 4.7e-04 1.7e-03
4 Brain gene expression ENSRNOG00000016226 0.04 0.03 1.2e-04 0.03 0.04 0.03 0.03 6.8e-04 2.1e-04 9.3e-04 1.1e-03
5 Brain isoform ratio ENSRNOT00000068617 0.06 0.03 1.2e-07 0.07 0.08 0.07 0.07 4.3e-07 1.2e-07 2.3e-07 4.1e-07
6 Brain isoform ratio ENSRNOT00000103750 0.03 0.03 2.9e-03 0.01 0.01 0.06 0.01 3.7e-02 1.6e-02 5.1e-06 8.7e-02
7 Brain mRNA stability ENSRNOG00000016226 0.05 0.03 2.4e-05 0.05 0.06 0.06 0.06 1.9e-05 4.3e-06 5.9e-06 4.9e-06
8 Liver isoform ratio ENSRNOT00000021877 0.03 0.02 1.0e-04 0.03 0.03 0.02 0.02 1.9e-04 6.6e-04 1.1e-03 1.2e-03
9 Liver isoform ratio ENSRNOT00000068617 0.07 0.03 4.2e-11 0.08 0.08 0.07 0.08 8.3e-09 4.1e-09 6.1e-08 6.7e-09
10 Liver mRNA stability ENSRNOG00000016226 0.06 0.03 1.1e-08 0.07 0.06 0.05 0.06 6.4e-08 1.7e-07 1.6e-06 2.4e-07
11 NAcc gene expression ENSRNOG00000016226 0.03 0.02 4.3e-03 0.02 0.02 0.02 0.02 6.4e-03 1.1e-02 7.1e-03 1.3e-02
12 NAcc mRNA stability ENSRNOG00000016226 0.04 0.03 2.1e-03 0.02 0.03 0.04 0.02 6.7e-03 2.2e-03 7.8e-04 9.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.10.20.80.50.5-0.9-0.50.4-0.0-0.10.20.40.1-0.7-0.2
BMI without tail0.30.72.61.00.9-1.6-0.90.60.4-0.1-0.20.6-0.2-1.01.2
Body weight0.21.15.20.90.7-1.4-1.00.41.10.1-0.60.4-0.7-0.72.3
Epididymis fat weight1.12.77.61.91.7-2.7-1.91.4-0.2-1.0-1.61.5-1.7-1.90.1
Glucose0.50.71.3-0.8-0.91.10.9-0.70.20.61.1-0.81.01.0-0.2
Heart weight0.71.01.61.31.0-1.0-1.01.00.2-0.9-1.11.0-1.1-1.1-0.9
Left kidney weight0.10.31.70.50.3-1.3-0.60.00.20.2-0.40.1-0.5-0.11.1
Right kidney weight0.31.03.51.31.0-1.9-1.30.90.2-0.4-0.70.9-0.7-1.0-0.1
Tail length0.51.53.41.31.2-1.5-1.50.81.0-0.1-1.40.8-1.3-0.91.8
Length with tail0.41.55.31.00.9-1.1-1.30.71.60.0-1.50.6-1.4-0.72.3
Length without tail0.10.31.4-0.4-0.31.10.2-0.11.20.3-0.0-0.3-0.10.30.7
Liver weight, left0.20.30.5-0.7-0.40.60.6-0.5-0.00.60.6-0.50.50.5-0.1
Liver weight, right0.00.10.6-0.10.10.7-0.0-0.0-0.10.1-0.0-0.1-0.10.20.4
Parametrial fat weight2.34.68.42.32.5-1.8-2.92.0-0.3-1.5-2.82.1-2.7-2.1-1.1
Retroperitoneal fat weight0.20.53.40.60.5-1.8-0.80.1-0.20.0-0.50.3-0.5-0.41.1
Intraocular pressure0.71.01.71.30.9-0.5-1.01.2-0.8-1.3-0.71.1-0.7-0.8-1.1
Extensor digitorum longus weight1.14.69.6-2.2-2.23.12.3-1.81.71.82.2-2.12.32.11.4
Soleus weight0.00.00.1-0.1-0.00.30.20.10.2-0.1-0.00.10.0-0.40.4
Tibialis anterior weight0.00.10.5-0.1-0.1-0.20.3-0.10.30.20.7-0.10.7-0.1-0.2
Tibia length0.20.51.10.80.6-1.0-0.60.5-0.5-0.7-0.70.7-0.7-0.6-0.6
Number of licking bursts0.20.20.4-0.4-0.4-0.50.6-0.4-0.40.20.6-0.30.7-0.0-0.6
Food consumed during 24 hour testing period0.20.21.80.00.0-1.40.1-0.1-0.7-0.2-0.00.10.0-0.4-0.4
Times rat made contact with spout0.10.10.3-0.3-0.4-0.30.5-0.2-0.5-0.30.4-0.00.2-0.1-0.6
Mean time between licks in bursts0.71.02.1-1.1-1.00.71.1-1.00.71.11.0-1.11.40.80.3
Mean num. licks in bursts0.10.10.30.20.20.0-0.30.2-0.1-0.3-0.30.2-0.5-0.10.2
Std. dev. time between licks in bursts0.81.01.30.81.10.2-1.11.1-0.9-1.0-1.11.1-1.1-1.1-0.9
Water consumed over 24 hours0.30.31.9-0.5-0.6-1.40.6-0.6-0.30.10.5-0.30.30.1-0.2
Indifference point 0 sec2.84.67.52.62.3-1.7-2.02.7-0.6-2.4-1.82.6-1.9-2.7-0.9
Indifference point AUC0.91.11.91.11.1-0.5-1.11.2-0.3-1.1-1.11.2-1.2-1.4-0.6
Indifference point function ln k0.50.71.3-1.1-0.90.21.0-0.90.00.80.8-0.91.00.80.5
Indifference point function log k0.50.71.3-1.1-0.90.21.0-0.90.00.80.8-0.91.00.80.5
Delay discounting total patch changes 0 sec2.54.17.12.52.2-1.8-1.92.5-0.5-2.3-1.62.5-1.7-2.7-0.8
Delay discounting total patch changes 12 sec4.15.48.92.72.5-1.7-2.32.7-0.9-2.5-2.02.7-2.1-3.0-1.8
Delay discounting total patch changes 18 sec6.48.413.03.43.1-1.5-2.73.5-1.0-3.3-2.73.4-2.8-3.6-2.6
Delay discounting total patch changes 24 sec1.72.23.01.71.4-1.1-1.31.6-1.0-1.6-1.41.6-1.5-1.4-1.7
Delay discounting total patch changes 6 sec2.13.25.22.02.0-1.2-1.92.2-0.7-1.8-1.72.1-1.8-2.3-1.1
Delay discounting time to switch 0 sec1.92.84.4-1.7-2.00.22.0-2.00.21.42.1-1.82.11.9-1.2
Delay discounting water rate 0 sec1.52.34.21.61.70.1-1.42.10.1-1.8-1.61.8-1.6-2.00.3
Delay discounting water rate 12 sec0.20.31.7-0.1-0.01.30.20.31.0-0.2-0.10.1-0.1-0.01.0
Delay discounting water rate 18 sec0.30.40.9-0.5-0.70.30.7-0.60.40.50.3-0.60.40.80.9
Delay discounting water rate 24 sec0.20.31.4-0.4-0.51.20.8-0.10.6-0.20.5-0.20.60.10.5
Delay discounting water rate 6 sec0.50.73.10.30.31.7-0.10.70.3-0.8-1.20.5-1.1-0.40.5
Locomotor activity0.10.10.30.1-0.2-0.10.50.00.2-0.6-0.30.2-0.2-0.30.4
Locomotor testing distance0.10.10.8-0.2-0.50.10.9-0.1-0.0-0.50.00.00.1-0.2-0.4
Locomotor testing rearing0.10.10.30.20.10.30.00.40.4-0.5-0.60.4-0.4-0.5-0.2
Light reinforcement 10.61.02.4-1.3-1.3-0.11.5-1.20.40.91.1-1.11.10.7-0.0
Light reinforcement 20.81.11.8-1.0-1.0-0.41.1-1.20.91.31.1-1.11.00.81.3
Reaction time number correct0.40.52.10.40.31.4-0.10.8-0.2-1.1-0.70.7-0.8-0.4-0.5
Reaction time mean minus median0.50.62.10.60.6-1.4-0.90.3-0.9-0.5-0.70.5-0.8-0.4-0.9
Reaction time mean minus median AUC0.30.40.90.30.4-0.5-0.60.3-1.0-0.6-0.80.4-0.8-0.1-0.9
Reaction time num false alarms1.52.04.51.51.6-2.1-1.51.5-0.7-1.3-1.01.6-1.0-1.9-0.6
Reaction time num false alarms AUC1.92.75.21.91.9-2.3-1.81.7-0.9-1.5-1.31.8-1.3-2.1-0.5
Reaction time trials correct on left0.40.52.10.40.31.4-0.10.8-0.2-1.1-0.70.7-0.8-0.4-0.5
Reaction time trials on left0.30.52.40.30.31.5-0.00.7-0.2-1.1-0.70.6-0.7-0.3-0.4
Reaction time mean0.40.64.60.60.6-2.2-0.90.2-0.70.1-0.10.3-0.1-0.5-0.0
Reaction time mean AUC0.50.65.00.50.6-2.2-0.90.2-0.60.1-0.20.3-0.2-0.5-0.1
Median of all reaction times0.40.54.10.40.4-2.0-0.70.0-0.50.30.20.20.2-0.50.3
Reaction time omissions0.10.21.70.30.11.30.00.30.3-0.40.10.20.00.20.3
Reaction time false alarm rate1.01.45.61.31.3-2.4-1.31.0-0.6-0.6-0.61.1-0.6-1.5-0.1
Reaction time premature initiation rate1.52.03.8-1.4-1.8-0.61.5-2.00.81.51.3-1.71.31.8-0.2
Reaction time premature initiations1.01.42.8-1.3-1.70.51.6-1.50.80.81.0-1.31.01.6-0.5
Std. dev. reaction times0.10.21.90.10.1-1.4-0.5-0.2-0.40.20.1-0.10.00.2-0.2
Reaction time trials completed0.30.52.40.30.31.5-0.00.7-0.2-1.1-0.70.6-0.7-0.3-0.4
Reaction time trials AUC0.40.62.20.40.41.5-0.10.9-0.3-1.2-0.80.8-0.8-0.5-0.5
Social response proportion0.60.71.71.10.9-1.3-1.00.60.4-0.2-0.50.6-0.5-1.01.1
Social responses0.50.63.60.90.5-1.9-0.50.5-0.3-0.7-0.30.7-0.4-0.80.1
Social time0.71.01.61.21.1-1.3-1.10.9-0.8-1.0-0.81.1-0.9-1.0-0.1
Conditioned locomotion1.21.52.51.61.4-1.1-1.31.4-0.2-1.2-1.11.4-1.1-1.6-0.4
Cocaine response after cond. corrected1.31.42.41.31.41.0-1.21.60.1-1.2-1.31.3-1.3-1.5-0.5
Cocaine response after cond. not corrected1.31.42.21.11.31.1-1.11.5-0.4-1.3-1.41.3-1.5-1.3-0.7
Cocaine response before conditioning0.10.10.6-0.3-0.2-0.40.2-0.3-0.8-0.2-0.2-0.1-0.50.4-0.1
Saline control response0.60.72.00.80.7-1.4-0.80.70.6-0.7-0.90.8-1.0-1.10.3
Condit. Reinf. active minus inactive responses0.10.11.00.2-0.0-1.00.00.00.3-0.2-0.10.1-0.1-0.30.2
Condit. Reinf. active-inactive response ratio0.20.20.50.60.5-0.7-0.50.40.0-0.3-0.60.5-0.6-0.50.2
Condit. Reinf. active responses0.30.42.00.50.4-1.4-0.40.40.4-0.4-0.70.5-0.6-0.80.3
Condit. Reinf. inactive responses0.60.81.90.70.8-1.4-0.80.80.3-0.7-1.10.8-1.0-1.2-0.0
Condit. Reinf. lever presses0.60.81.80.80.7-1.3-0.50.8-0.4-1.1-0.91.0-0.8-1.2-0.5
Condit. Reinf. lever reinforcers received0.71.02.51.00.9-1.6-0.90.90.2-0.9-1.21.0-1.1-1.40.1
Pavlov. Cond. lever latency1.31.72.6-1.3-1.21.51.2-1.30.71.51.5-1.51.41.60.9
Pavlov. Cond. magazine entry latency1.21.42.51.41.0-1.1-0.91.2-1.0-1.6-0.91.4-1.1-1.2-1.3
Pavlov. Cond. change in total contacts0.91.31.81.21.0-1.3-1.01.1-0.7-1.3-1.21.3-1.1-1.2-1.1
Pavlov. Cond. index score1.31.72.71.41.1-1.4-1.01.3-0.9-1.6-1.31.5-1.3-1.5-1.2
Pavlov. Cond. latency score1.21.52.51.31.0-1.3-0.91.2-1.0-1.6-1.21.4-1.2-1.3-1.2
Pavlov. Cond. lever contacts0.91.22.11.11.0-1.4-1.01.1-0.4-1.2-1.31.2-1.1-1.4-0.7
Pavlov. Cond. magazine entry number2.02.43.4-1.8-1.51.61.4-1.61.21.91.3-1.81.51.61.5
Pavlov. Cond. intertrial magazine entries0.00.10.3-0.0-0.20.30.3-0.1-0.6-0.4-0.10.0-0.10.20.0
Pavlov. Cond. lever-magazine prob. diff.1.41.93.11.51.2-1.4-1.11.4-1.0-1.8-1.31.6-1.3-1.5-1.3
Pavlov. Cond. response bias1.11.62.41.41.2-1.2-1.11.4-0.6-1.5-1.21.5-1.2-1.6-1.1
Conditioned reinforcement - actives0.30.31.6-0.4-0.60.10.6-0.60.10.30.3-0.50.20.71.3
Conditioned reinforcement - inactives0.80.92.1-1.0-0.81.41.1-0.51.20.50.8-0.70.70.61.4
Conditioned locomotion0.81.03.3-0.8-1.00.81.2-0.80.90.60.8-0.80.80.91.8
Intermittent access intake day 1-15 change8.48.420.8-3.0-3.01.83.0-3.01.62.62.5-3.02.73.04.6
Intermittent access intake escalation10.810.727.2-3.3-3.41.83.3-3.51.72.92.7-3.42.93.55.2
Intermittent access intake escalation 27.67.515.9-3.0-2.92.33.1-2.71.42.12.5-2.72.52.84.0
Intermitt. access day 1 inactive lever presses0.10.10.70.3-0.0-0.8-0.1-0.20.40.20.0-0.1-0.1-0.00.8
Intermitt. access day 15 inactive lever presses3.13.47.8-2.0-2.10.02.2-1.90.51.22.1-1.72.01.62.8
Intermitt. access escalation Index0.50.41.0-0.3-0.7-0.50.4-0.90.10.70.6-0.70.50.81.0
Intermittent access day 1 total infusions0.20.30.50.60.50.2-0.50.70.1-0.7-0.50.6-0.7-0.4-0.4
Intermittent access day 15 total infusions3.84.212.5-2.0-2.11.12.0-2.21.21.81.6-2.11.62.33.5
Intermittent access terminal intake (last 3 days)1.01.13.9-1.1-1.10.91.0-1.10.70.70.7-1.00.61.32.0
Intermittent access total infusions0.50.61.8-0.8-0.71.10.8-0.60.60.40.4-0.60.30.91.4
Intermittent access day 1 locomotion0.20.20.90.2-0.20.20.1-0.11.00.10.1-0.20.00.30.8
Intermittent access day 15 total locomotion2.22.47.3-1.5-1.41.81.4-1.31.71.31.0-1.40.91.52.7
Intermittent access total locomotion0.80.93.3-0.7-0.81.00.9-0.71.40.60.7-0.70.70.91.8
Intermittent access standard deviation2.12.25.2-1.4-1.61.21.5-1.60.51.11.1-1.61.02.02.3
Cocaine induced anxiety0.30.33.10.50.2-1.8-0.4-0.1-0.50.1-0.00.10.2-0.2-0.3
Post-drug Anxiety0.20.21.20.10.2-0.6-0.4-0.2-1.10.1-0.3-0.0-0.10.1-0.7
Baseline Anxiety1.11.22.90.41.01.1-0.81.1-0.7-1.0-1.21.0-1.4-0.8-1.7
Lifetime Intake0.70.72.0-0.9-0.81.21.0-0.60.60.30.7-0.70.51.01.4
Incentive Sensitization - Responses1.81.85.4-1.4-1.31.11.4-1.21.01.11.2-1.31.11.12.3
Incentive Sensitization - Breakpoint1.91.95.6-1.4-1.41.01.4-1.31.01.11.2-1.31.11.22.4
Progressive ratio test 1 active lever presses0.91.02.6-1.0-1.01.61.1-0.80.50.60.7-0.90.61.11.3
Progressive ratio test 1 breakpoint1.31.33.0-1.2-1.11.71.3-0.90.80.70.9-1.00.81.31.6
Progressive ratio test 1 inactive lever presses0.40.51.3-0.6-0.50.20.7-0.31.10.40.8-0.40.90.31.1
Progressive ratio test 2 active lever presses1.82.05.0-1.5-1.41.81.5-1.21.00.90.9-1.30.81.52.2
Progressive ratio test 2 breakpoint2.32.55.8-1.7-1.62.01.8-1.41.11.11.3-1.51.11.62.4
Progressive ratio test 2 inactive lever presses1.92.27.3-1.4-1.50.91.7-1.21.30.91.4-1.21.21.32.7
Total sessions with >9 infusions0.70.82.2-0.7-0.81.50.9-0.41.00.20.5-0.50.31.11.5
Short access day 1 total inactive lever presses0.20.31.1-0.2-0.3-0.50.4-0.21.0-0.00.5-0.20.4-0.21.0
Short access day 10 total inactive lever presses0.30.40.7-0.6-0.6-0.40.4-0.70.20.70.6-0.60.60.50.9
Short access day 1 total infusions1.21.32.8-1.0-1.20.81.3-1.00.80.71.3-1.01.11.21.7
Short access day 10 total infusions0.10.10.30.20.2-0.2-0.20.3-0.1-0.5-0.20.3-0.4-0.10.0
Short access total infusions0.30.30.8-0.5-0.50.90.6-0.30.50.00.4-0.30.20.60.8
Short access day 1 locomotion1.11.13.3-0.9-1.10.71.1-1.00.90.81.0-1.00.91.11.8
Short access day 10 total locomotion0.50.62.4-0.5-0.7-0.00.7-0.80.80.70.6-0.70.60.71.5
Short access total locomotion2.02.05.2-1.3-1.51.31.6-1.31.20.91.4-1.31.31.52.3
Compulsive drug intake0.80.81.5-1.0-1.00.21.1-0.90.20.70.9-0.91.20.81.0
One hour access (0.3 mA shock)2.83.38.1-1.9-1.91.42.0-1.61.41.41.8-1.71.81.72.8
One hour access (shock baseline)0.10.10.3-0.4-0.20.60.3-0.10.3-0.10.2-0.1-0.10.20.5
Number of responses in last shaping day2.72.86.0-1.6-1.91.02.0-1.60.81.21.8-1.61.71.72.4
Context. condit. distance diff. score0.81.02.30.81.0-1.5-1.30.6-0.6-0.5-1.30.8-1.3-0.9-0.2
Locomotion velocity, session 10.90.91.7-1.0-1.10.11.3-1.10.10.91.3-1.01.30.9-0.0
Locomotion distance, session 10.40.51.60.60.5-1.3-0.40.3-1.2-0.5-0.10.6-0.1-0.4-1.1
Locomotion velocity, session 22.42.95.9-1.7-2.10.22.3-1.80.41.32.4-1.72.41.60.1
Locomotion distance, session 20.40.50.9-0.6-0.90.20.9-0.90.00.60.9-0.80.90.90.1
Locomotion velocity, session 31.51.73.8-1.2-1.51.41.9-1.1-0.40.31.8-1.01.81.3-0.3
Locomotion distance, session 30.30.41.60.60.4-0.0-0.20.6-1.2-0.9-0.40.7-0.3-0.4-0.7
Stereotopy head waving bouts, day 33.44.05.8-2.2-2.20.52.0-2.41.72.42.0-2.42.02.11.7
Stereotopy head waving duration, day 31.31.52.1-1.1-1.4-0.21.2-1.41.31.41.4-1.41.41.10.8
Locomotion velocity, session 70.30.30.7-0.8-0.70.40.6-0.6-0.00.40.6-0.60.60.80.1
Locomotion distance, session 70.20.30.60.40.60.0-0.70.50.1-0.2-0.80.4-0.8-0.50.5
Stereotopy head waving bouts, day 70.40.41.0-0.7-0.90.31.0-0.8-0.20.30.4-0.70.40.90.2
Stereotopy head waving duration, day 71.11.42.5-1.2-1.5-0.01.6-1.5-0.10.91.3-1.31.31.50.1
Locomotion velocity, session 80.60.71.5-0.9-0.81.01.0-0.60.50.51.2-0.71.20.5-0.2
Locomotion distance, session 80.20.20.80.40.4-0.9-0.50.2-0.6-0.3-0.50.4-0.5-0.4-0.3
Degree of sensitization distance0.40.41.40.20.5-0.4-0.90.21.20.5-0.60.1-0.6-0.40.8
Degree of sensitization stereotypy0.10.20.4-0.4-0.50.30.6-0.4-0.6-0.20.1-0.20.10.6-0.1
Condit. Reinf. active minus inactive responses0.20.20.90.20.20.90.00.6-0.1-0.50.20.40.2-0.4-0.3
Condit. Reinf. active-inactive response ratio0.20.31.50.30.11.20.20.6-0.0-0.60.30.40.3-0.5-0.5
Condit. Reinf. active responses0.10.10.40.10.20.60.00.4-0.2-0.30.30.30.3-0.3-0.2
Condit. Reinf. inactive responses0.00.10.20.10.4-0.4-0.40.2-0.10.1-0.20.2-0.2-0.20.1
Incentive salience index mean0.10.10.4-0.2-0.10.60.30.10.1-0.10.5-0.00.40.00.0
Condit. Reinf. lever presses0.20.30.4-0.6-0.60.60.6-0.40.30.30.6-0.50.60.60.5
Time in familiar zone, hab. session 17.97.510.62.93.0-1.7-3.02.9-1.6-2.8-3.23.0-3.3-3.0-1.7
Time in novel zone, hab. session 15.65.58.2-2.3-2.71.82.6-2.41.22.12.7-2.52.72.91.2
Total zone transitions, hab. session 10.10.10.3-0.0-0.1-0.60.2-0.3-0.60.00.3-0.10.30.2-0.2
Total locomotion distance, hab. session 10.20.32.10.40.2-1.4-0.3-0.0-0.7-0.3-0.40.2-0.4-0.1-0.3
Locomotion velocity, hab. session 10.20.31.90.50.4-1.4-0.50.1-0.7-0.4-0.60.4-0.5-0.2-0.3
Time in familiar zone, hab. session 21.71.82.81.11.40.3-1.21.5-1.2-1.7-1.51.5-1.6-1.5-1.3
Time in novel zone, hab. session 20.20.20.40.0-0.20.60.2-0.10.60.40.4-0.30.50.50.7
Total zone transitions, hab. session 20.10.10.2-0.1-0.3-0.30.3-0.3-0.4-0.10.2-0.10.20.3-0.5
Total locomotion distance, hab. session 20.10.10.60.2-0.1-0.80.1-0.2-0.6-0.4-0.10.1-0.10.1-0.6
Locomotion velocity, hab. session 20.20.20.8-0.3-0.6-0.90.5-0.7-0.30.10.3-0.40.40.5-0.3
Novel to familiar place preference ratio0.20.22.40.20.1-1.6-0.2-0.1-0.10.3-0.20.0-0.2-0.20.1
Novelty place preference0.20.21.60.20.1-1.3-0.1-0.1-0.30.1-0.20.1-0.2-0.2-0.1
Time in novel zone, NPP test0.20.21.50.40.3-1.2-0.30.1-0.4-0.1-0.40.3-0.4-0.4-0.2
Total zone transitions, NPP test0.10.10.70.20.1-0.8-0.20.0-0.6-0.3-0.10.2-0.10.0-0.7
Total locomotion distance, NPP test0.20.32.0-0.1-0.3-1.40.1-0.5-0.50.20.2-0.30.20.5-0.4
Locomotion velocity, NPP test0.30.42.3-0.3-0.5-1.50.3-0.8-0.30.50.4-0.50.40.7-0.3
Pavlov. Cond. lever latency0.30.30.60.80.50.0-0.50.70.1-0.7-0.40.6-0.5-0.7-0.7
Pavlov. Cond. magazine entry latency0.20.31.1-0.4-0.1-1.00.0-0.5-0.10.8-0.0-0.40.00.10.9
Pavlov. Cond. change in total contacts0.40.41.5-0.8-0.40.50.4-0.70.10.80.2-0.70.20.71.2
Pavlov. Cond. index score0.10.10.4-0.30.1-0.5-0.1-0.2-0.40.4-0.2-0.1-0.20.00.6
Pavlov. Cond. latency score0.10.20.5-0.6-0.1-0.40.1-0.5-0.20.70.1-0.40.10.40.7
Pavlov. Cond. lever contacts0.10.20.5-0.7-0.30.10.3-0.4-0.20.50.3-0.40.30.40.5
Pavlov. Cond. magazine entry number0.20.30.60.80.40.3-0.40.70.0-0.7-0.30.6-0.3-0.4-0.8
Pavlov. Cond. intertrial magazine entries1.82.25.61.41.20.8-0.81.9-1.2-2.4-1.01.8-1.0-1.6-1.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.00.4-0.7-0.30.1-0.50.0-0.50.2-0.5-0.40.4
Pavlov. Cond. response bias0.20.20.6-0.7-0.4-0.20.4-0.6-0.20.60.2-0.50.20.40.7
Bone: apparent density0.20.30.9-0.6-0.41.00.5-0.20.70.40.5-0.40.50.30.4
Bone surface1.01.82.91.31.50.5-1.31.7-0.6-1.5-1.41.6-1.4-1.5-1.0
Bone volume0.40.71.10.70.90.4-0.71.1-0.5-1.0-0.91.0-0.9-1.0-0.7
Bone: connectivity density0.30.50.90.60.80.7-0.71.00.1-0.6-0.80.8-0.6-0.7-0.4
Bone: cortical apparent density0.40.62.3-0.4-0.81.51.1-0.2-0.2-0.40.9-0.30.80.5-0.8
Bone: cortical area0.30.51.10.60.70.1-0.70.7-0.5-0.7-1.00.7-1.1-0.6-0.4
Bone: cortical porosity7.27.810.9-2.9-3.22.33.3-2.91.62.53.2-3.03.22.81.9
Bone: cortical porosity8.49.011.8-3.2-3.42.73.4-3.11.92.73.3-3.23.33.12.3
Bone: cortical thickness0.10.10.5-0.3-0.40.70.5-0.3-0.2-0.00.2-0.20.10.4-0.2
Bone: cortical thickness0.81.02.20.91.00.3-1.11.0-0.7-0.9-1.40.9-1.5-0.8-0.7
Bone: cortical tissue density0.40.52.2-0.3-0.81.51.0-0.2-0.3-0.50.9-0.20.80.5-0.8
Bone: elastic displacement1.21.33.51.31.3-1.9-1.51.0-0.8-0.6-1.01.1-0.9-1.0-1.0
Bone: elastic work0.50.71.20.70.8-0.9-0.90.7-1.0-0.7-0.70.8-0.7-0.6-1.1
Bone: endosteal estimation0.40.92.60.51.2-0.3-1.60.80.60.0-1.50.6-1.5-0.60.6
Bone: endosteal perimeter1.22.44.71.52.0-0.5-2.21.7-0.3-1.0-2.11.5-2.0-1.6-0.4
Bone: final force0.71.13.0-1.3-1.11.71.1-0.90.70.70.7-1.00.61.30.8
Bone: final moment0.81.42.7-1.4-1.31.71.3-1.10.80.90.9-1.20.81.40.9
Bone: marrow area0.40.82.50.51.1-0.3-1.60.70.70.1-1.40.5-1.4-0.50.7
Bone: maximum diameter0.50.91.71.01.2-0.3-1.21.0-0.5-0.8-1.31.0-1.3-0.9-0.4
Bone: maximum force0.40.72.4-1.0-0.91.50.8-0.70.70.60.5-0.80.41.00.7
Bone: maximum moment0.61.12.3-1.2-1.11.51.1-1.00.70.80.8-1.10.71.20.8
Bone: minimum diameter0.40.82.00.71.1-0.1-1.30.90.2-0.3-1.40.8-1.4-0.80.1
Bone: periosteal estimation0.40.82.30.51.10.0-1.40.80.2-0.2-1.50.7-1.5-0.60.2
Bone: periosteal perimeter0.81.32.61.11.4-0.1-1.41.3-0.5-1.0-1.61.2-1.6-1.1-0.5
Bone: post-yield work0.30.41.20.30.8-0.8-1.10.30.10.3-0.90.3-0.9-0.40.2
Bone: stiffness1.52.44.8-1.7-1.72.21.8-1.41.11.11.3-1.61.31.61.2
Bone: tissue strength2.32.24.4-1.5-1.90.42.0-1.50.60.92.1-1.42.01.50.6
Bone: trabecular number0.10.20.40.40.60.3-0.50.60.1-0.4-0.60.5-0.5-0.6-0.2
Bone: trabecular spacing0.00.00.1-0.2-0.3-0.20.2-0.3-0.20.00.1-0.20.10.2-0.1
Bone: trabecular thickness0.10.10.2-0.4-0.3-0.40.3-0.40.20.50.3-0.40.30.30.4
Bone: trabecular tissue density2.83.95.6-2.2-2.20.32.2-2.40.82.12.3-2.22.32.11.5
Breakpoint value in progressive ratio session0.70.81.61.21.00.1-0.91.3-0.4-1.2-0.51.2-0.5-1.0-0.8
Distance traveled before self-admin0.30.40.80.70.5-0.9-0.70.4-0.6-0.5-0.60.5-0.6-0.4-0.6
Distance traveled after self-admin0.50.50.80.90.8-0.8-0.70.8-0.7-0.7-0.20.9-0.2-0.9-0.7
Delta time in closed arm before/after self-admin1.01.01.61.11.2-0.2-1.11.2-0.7-0.9-1.31.1-1.3-1.1-0.2
Delta time in open arm before/after self-admin0.60.61.4-0.5-0.6-0.10.7-0.51.20.81.2-0.61.20.30.7
Diff in mean of infusions in LGA sessions0.40.41.31.20.8-0.2-0.80.8-0.1-0.5-0.30.7-0.3-0.7-0.4
Extinction: sum of active levers before priming1.61.63.6-1.6-1.51.01.9-1.10.10.51.8-1.01.81.00.1
Active lever presses in extinction session 60.60.61.60.91.00.0-0.90.9-1.3-0.5-0.30.8-0.3-0.6-0.9
Delta distance traveled before/after self-admin0.00.10.20.10.20.20.10.40.2-0.20.10.30.1-0.40.1
Delta ambulatory time before/after self-admin0.10.10.50.00.10.70.10.50.3-0.4-0.00.30.0-0.30.2
Time in closed arm before self-admin1.51.74.91.51.7-1.1-2.21.0-0.8-0.3-1.61.0-1.6-1.1-0.6
Time in closed arm after self-admin0.60.61.60.60.8-1.0-1.20.2-0.40.2-1.30.3-1.2-0.50.2
Time in open arm before self-admin0.40.41.1-0.8-0.80.21.0-0.60.0-0.10.9-0.40.90.6-0.4
Time in open arm after self-admin1.11.22.9-1.0-1.30.51.7-0.80.80.41.7-0.81.70.80.3
Sum of active levers in priming session hrs 5-61.71.73.8-1.2-1.21.81.6-0.90.50.62.0-1.01.91.30.1
Time to tail flick, vehicle, before self-admin0.40.43.10.1-0.0-1.80.20.00.5-0.30.50.20.5-0.4-0.5
Time to tail flick, vehicle, after self-admin0.10.10.4-0.40.00.60.10.20.3-0.4-0.00.2-0.0-0.0-0.1
Time to tail flick, test, before self-admin0.70.73.20.70.6-1.8-0.40.7-0.4-0.6-0.10.8-0.1-1.2-0.8
Time to tail flick, test, after self-admin0.20.21.40.20.1-1.2-0.1-0.10.50.30.5-0.00.5-0.20.3
Delta time to tail flick, vehicle, before/after SA1.41.45.2-1.4-1.02.31.0-1.00.21.10.9-1.20.91.40.7
Delta time to tail flick, test, before/after SA0.20.20.70.30.40.8-0.50.2-0.2-0.0-0.60.1-0.50.00.3
Ambulatory time before self-admin0.10.11.20.2-0.0-1.1-0.2-0.2-0.2-0.10.00.0-0.00.1-0.3
Ambulatory time after self-admin0.30.30.50.60.6-0.7-0.50.7-0.4-0.7-0.30.7-0.2-0.6-0.5
Total heroin consumption0.40.52.0-0.1-0.60.20.7-0.30.30.21.4-0.41.40.6-0.4
Area under the delay curve0.20.21.0-0.10.1-1.00.20.2-0.9-0.50.40.30.2-0.4-0.4
Delay disc. indifference point, 0s delay0.50.51.60.70.6-1.3-0.40.8-0.3-0.80.10.8-0.1-1.1-0.8
Delay disc. indifference point, 16s delay0.40.41.3-0.7-0.6-0.10.9-0.2-0.5-0.11.1-0.21.10.2-0.0
Delay disc. indifference point, 2s delay0.30.41.70.40.5-1.3-0.40.4-0.9-0.5-0.20.6-0.2-0.5-0.7
Delay disc. indifference point, 24s delay2.72.75.61.41.6-2.4-1.41.5-1.6-1.4-0.81.6-1.0-1.8-2.3
Delay disc. indifference point, 4s delay0.30.30.60.50.4-0.8-0.10.6-0.7-0.8-0.20.7-0.3-0.7-0.6
Delay disc. indifference point, 8s delay0.10.10.3-0.5-0.2-0.30.5-0.1-0.6-0.20.40.00.3-0.20.1
Delay discount exponential model param0.40.51.6-0.2-0.41.30.2-0.51.20.70.0-0.60.20.70.8
Delay discount hyperbolic model param0.50.51.6-0.3-0.51.30.2-0.51.10.80.1-0.70.20.70.8
Fecal boli incidents, locomotor time 10.91.03.2-0.7-1.10.01.2-0.70.80.51.5-0.81.80.61.1
Change in fecal boli incidents, locomotor task0.50.54.5-0.3-0.02.10.20.20.8-0.1-0.5-0.0-0.50.10.4
Time >=10cm from walls, locomotor time 10.80.81.90.81.0-0.2-1.10.9-0.3-0.7-0.90.9-1.0-0.8-1.4
Bouts of movement, locomotor time 11.21.34.3-1.0-1.10.71.3-0.91.20.71.2-0.91.10.92.1
Total resting periods, locomotor time 10.30.31.4-0.1-0.20.50.50.01.20.00.2-0.10.2-0.11.2
Rest time, locomotor task time 10.91.02.81.20.9-0.4-0.41.31.1-1.1-0.81.2-0.3-1.7-0.1
Distance moved, locomotor task time 10.60.62.2-0.10.1-0.9-1.0-0.6-1.50.6-0.3-0.4-0.50.8-1.2
Vertical activity count, locomotor time 10.70.73.7-0.30.1-1.9-0.8-0.8-1.31.00.2-0.5-0.20.4-0.5
Time >=10cm from walls, locomotor time 20.91.04.30.10.72.1-0.80.70.6-0.3-1.70.4-1.4-0.3-0.6
Bouts of movement, locomotor time 23.33.67.9-2.1-2.01.82.4-1.61.11.11.8-1.62.01.72.8
Total resting periods, locomotor time 22.12.36.2-1.5-1.61.22.0-1.21.10.81.6-1.21.71.12.5
Rest time, locomotor task time 20.50.61.60.90.6-1.2-0.30.80.8-0.70.00.8-0.2-1.20.3
Distance moved, locomotor task time 20.50.62.50.00.40.4-0.70.2-1.5-0.2-0.90.2-0.80.2-1.6
Vertical activity count, locomotor time 20.60.71.80.50.6-1.3-1.00.1-1.3-0.0-1.00.3-0.8-0.1-1.1
Weight adjusted by age0.20.21.1-0.00.31.0-0.10.40.1-0.5-0.40.3-0.5-0.2-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.5-0.1-0.00.10.50.2-0.2-0.7-0.10.3-0.1-0.30.4
Locomotion in novel chamber1.11.43.71.51.2-1.2-1.31.1-0.9-0.9-0.81.1-0.7-1.1-1.9
Locomotion in novel chamber post-restriction2.12.53.9-1.2-1.7-1.11.4-1.9-0.51.52.0-1.62.01.81.7
Progressive ratio1.41.65.01.41.2-0.4-1.21.3-1.2-1.2-1.01.2-1.0-1.0-2.2
Food seeking constrained by brief footshock3.64.46.92.32.1-0.6-2.12.0-1.3-2.1-2.62.1-2.6-1.9-2.5
Seeking ratio, punishment vs. effort0.10.10.7-0.4-0.20.40.3-0.20.3-0.0-0.3-0.2-0.30.20.8
Run reversals in cocaine runway, females0.40.42.0-0.3-0.6-0.50.4-0.80.10.50.0-0.60.00.61.4
Run reversals in cocaine runway, males2.22.23.3-1.8-1.50.51.4-1.50.81.71.8-1.61.81.21.4
Latency to leave start box in cocaine runway1.31.43.8-0.9-1.2-0.21.4-1.10.71.01.4-1.01.40.81.9
Latency to leave start box in cocaine runway, F0.00.00.20.30.0-0.50.00.00.20.10.20.00.2-0.10.1
Latency to leave start box in cocaine runway, M4.03.910.8-1.8-2.10.72.2-1.91.31.72.0-1.92.01.63.3
Cd content in liver2.62.95.82.11.9-2.4-2.01.7-0.3-1.3-1.51.7-1.5-2.0-1.0
Co content in liver4.14.87.12.52.5-0.7-2.62.3-1.5-2.2-2.72.4-2.7-1.9-1.7
Cu content in liver5.76.911.23.03.2-1.0-3.32.9-0.6-2.1-3.02.8-3.0-2.8-2.1
Fe content in liver1.82.13.21.61.8-0.5-1.81.7-0.9-1.3-1.41.6-1.4-1.5-1.3
K content in liver1.21.22.0-1.3-1.30.71.4-1.10.40.91.4-1.11.40.90.1
Mg content in liver1.81.93.2-1.5-1.61.41.7-1.30.40.91.8-1.31.81.3-0.1
Mn content in liver0.60.71.8-0.8-0.90.81.2-0.6-0.40.11.3-0.61.30.5-0.7
Na content in liver0.80.81.6-0.9-0.8-0.30.8-1.00.71.31.0-1.01.00.80.9
Rb content in liver0.10.10.70.00.30.2-0.30.2-0.20.10.20.10.2-0.4-0.9
Se content in liver0.00.00.20.0-0.0-0.4-0.1-0.00.1-0.00.10.00.1-0.0-0.2
Sr content in liver1.51.32.61.21.2-1.6-1.31.0-0.9-0.9-1.11.1-1.1-1.3-1.0
Zn content in liver0.10.10.4-0.2-0.20.10.2-0.1-0.10.20.7-0.20.70.1-0.5