Ankfy1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016212 0.11 0.07 5.2e-10 0.06 0.06 0.06 0.04 7.9e-07 3.7e-07 4.5e-07 5.8e-05
2 Adipose mRNA stability ENSRNOG00000016212 0.12 0.08 1.3e-11 0.09 0.08 0.09 0.07 7.9e-10 1.7e-09 8.7e-10 3.2e-08
3 BLA gene expression ENSRNOG00000016212 0.13 0.09 8.8e-06 0.1 0.1 0.09 0.1 4.0e-06 6.1e-06 1.1e-05 6.9e-06
4 Brain gene expression ENSRNOG00000016212 0.1 0.06 2.6e-08 0.09 0.09 0.09 0.09 5.6e-09 2.8e-08 1.3e-08 9.4e-09
5 Eye gene expression ENSRNOG00000016212 0.29 0.18 8.6e-03 0.07 0.04 0.06 0.06 3.3e-02 9.1e-02 4.4e-02 4.2e-02
6 IL gene expression ENSRNOG00000016212 0.23 0.14 3.6e-03 0.04 0.03 0.03 0.04 3.1e-02 5.7e-02 7.6e-02 3.6e-02
7 LHb gene expression ENSRNOG00000016212 0.26 0.16 2.9e-03 0.01 0.02 0.02 0.02 1.5e-01 8.9e-02 8.8e-02 1.3e-01
8 Liver gene expression ENSRNOG00000016212 0.03 0.02 9.1e-03 0.01 0 0.01 0 2.6e-02 1.2e-01 5.1e-02 7.6e-02
9 Liver mRNA stability ENSRNOG00000016212 0.06 0.04 5.1e-05 0.03 0.02 0.02 0.03 2.5e-04 4.4e-03 1.0e-03 3.7e-04
10 PL gene expression ENSRNOG00000016212 0.05 0.04 1.8e-03 0.02 0.03 0.03 0.02 1.8e-02 3.5e-03 2.3e-03 6.1e-03
11 PL mRNA stability ENSRNOG00000016212 0.04 0.03 6.1e-03 0.03 0.03 0.03 0.03 1.3e-03 2.2e-03 3.1e-03 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail0.20.61.0-0.9-1.0-0.6-1.0-1.0-0.5-0.20.50.6-0.90.6
BMI without tail0.30.61.1-1.0-1.0-0.5-1.0-1.0-0.6-0.20.60.5-0.80.5
Body weight0.31.12.3-0.9-1.50.7-1.5-1.50.61.4-0.6-0.7-0.4-0.7
Epididymis fat weight2.55.910.2-3.1-3.1-1.8-3.2-3.1-1.9-1.01.81.8-2.81.8
Glucose0.50.81.90.30.9-0.90.90.9-0.9-1.40.90.9-0.10.9
Heart weight0.81.22.2-1.3-1.2-0.9-1.2-1.2-1.0-0.70.90.9-1.50.9
Left kidney weight0.20.50.8-0.6-0.2-0.7-0.3-0.2-0.8-0.90.90.7-0.90.7
Right kidney weight0.10.20.6-0.4-0.1-0.5-0.2-0.1-0.5-0.50.60.5-0.80.5
Tail length0.51.43.2-1.2-1.80.7-1.8-1.80.51.3-0.5-0.7-0.6-0.7
Length with tail0.31.22.7-0.5-1.01.3-1.1-1.01.01.7-1.1-1.30.1-1.3
Length without tail0.30.61.3-0.5-1.00.6-1.1-1.00.50.9-0.6-0.6-0.3-0.6
Liver weight, left0.20.41.10.2-0.20.7-0.2-0.20.81.0-0.8-0.70.4-0.7
Liver weight, right0.40.71.7-1.1-1.3-0.4-1.3-1.3-0.40.00.30.4-0.90.4
Parametrial fat weight7.614.929.5-4.8-5.3-2.7-5.4-5.3-2.6-1.32.72.7-4.32.7
Retroperitoneal fat weight0.30.91.3-0.8-0.6-1.1-0.5-0.6-1.1-1.11.11.1-1.01.1
Intraocular pressure1.82.54.3-1.4-0.9-1.8-0.8-0.9-1.9-2.11.81.8-1.51.8
Extensor digitorum longus weight3.513.918.0-4.2-4.2-3.4-4.2-4.2-3.4-2.73.43.4-4.13.4
Soleus weight1.13.39.0-2.3-3.0-0.4-3.0-3.0-0.40.50.40.4-1.70.4
Tibialis anterior weight2.79.316.6-3.7-4.1-2.2-4.0-4.1-2.3-1.42.32.2-3.32.2
Tibia length0.92.54.71.00.52.00.50.52.02.2-2.0-2.01.2-2.0
Number of licking bursts0.20.20.40.60.60.30.60.60.30.2-0.3-0.30.6-0.3
Food consumed during 24 hour testing period0.80.91.40.90.61.00.60.61.21.2-1.1-1.01.0-1.0
Times rat made contact with spout1.61.82.01.41.31.41.31.31.41.2-1.3-1.41.4-1.4
Mean time between licks in bursts1.11.53.1-1.5-1.8-0.9-1.8-1.8-0.8-0.40.70.9-1.40.9
Mean num. licks in bursts0.10.10.30.20.10.50.10.10.50.5-0.4-0.50.2-0.5
Std. dev. time between licks in bursts0.40.50.9-0.8-1.0-0.5-1.0-1.0-0.6-0.30.50.5-0.70.5
Water consumed over 24 hours4.95.87.12.42.02.52.02.02.62.5-2.6-2.52.7-2.5
Indifference point 0 sec2.23.64.41.81.72.11.71.72.01.9-1.9-2.11.8-2.1
Indifference point AUC2.22.64.6-1.5-0.7-1.7-0.9-0.7-1.9-2.02.11.7-1.91.7
Indifference point function ln k7.110.112.83.22.43.42.52.43.43.3-3.5-3.43.6-3.4
Indifference point function log k7.110.112.83.22.43.42.52.43.43.3-3.5-3.43.6-3.4
Delay discounting total patch changes 0 sec1.52.53.11.51.41.81.51.41.61.6-1.5-1.81.5-1.8
Delay discounting total patch changes 12 sec1.11.42.2-1.3-0.9-1.2-0.9-0.9-1.2-1.11.41.2-1.51.2
Delay discounting total patch changes 18 sec0.40.51.1-0.9-0.4-0.5-0.5-0.4-0.7-0.71.00.5-1.00.5
Delay discounting total patch changes 24 sec0.40.51.2-0.6-0.0-0.7-0.2-0.0-0.9-0.91.10.7-0.90.7
Delay discounting total patch changes 6 sec1.21.93.7-1.3-0.6-1.3-0.6-0.6-1.5-1.61.91.3-1.81.3
Delay discounting time to switch 0 sec1.62.43.0-1.7-1.7-1.5-1.6-1.7-1.2-1.11.41.5-1.71.5
Delay discounting water rate 0 sec0.60.91.51.21.10.81.11.10.80.6-0.8-0.81.2-0.8
Delay discounting water rate 12 sec0.20.31.0-0.5-0.9-0.2-1.0-0.9-0.20.10.10.2-0.30.2
Delay discounting water rate 18 sec0.81.02.10.70.11.20.10.11.31.5-1.4-1.20.9-1.2
Delay discounting water rate 24 sec0.10.20.4-0.1-0.6-0.6-0.6-0.6-0.3-0.30.10.6-0.00.6
Delay discounting water rate 6 sec0.10.20.60.70.30.30.20.30.40.2-0.5-0.30.8-0.3
Locomotor activity0.61.01.4-1.1-1.2-0.9-1.2-1.2-0.9-0.70.90.9-1.10.9
Locomotor testing distance3.65.96.5-2.5-2.4-2.4-2.5-2.4-2.4-2.12.52.4-2.52.4
Locomotor testing rearing4.26.78.5-2.7-2.2-2.6-2.3-2.2-2.8-2.62.82.6-2.92.6
Light reinforcement 11.52.73.2-1.8-1.6-1.6-1.6-1.6-1.6-1.41.61.6-1.81.6
Light reinforcement 20.20.30.5-0.4-0.3-0.7-0.3-0.3-0.5-0.60.60.7-0.50.7
Reaction time number correct0.10.10.3-0.1-0.5-0.0-0.5-0.50.10.3-0.30.00.20.0
Reaction time mean minus median0.30.41.10.81.10.41.01.10.30.0-0.3-0.40.4-0.4
Reaction time mean minus median AUC0.10.10.30.30.50.10.50.50.0-0.1-0.1-0.10.0-0.1
Reaction time num false alarms1.01.42.41.31.51.11.61.50.90.6-0.9-1.11.3-1.1
Reaction time num false alarms AUC0.71.01.81.21.30.81.41.30.70.4-0.7-0.81.1-0.8
Reaction time trials correct on left0.10.10.3-0.1-0.5-0.0-0.5-0.50.10.3-0.30.00.20.0
Reaction time trials on left0.10.10.3-0.1-0.5-0.1-0.5-0.50.10.2-0.30.10.20.1
Reaction time mean0.20.20.50.50.70.30.70.70.30.2-0.3-0.30.2-0.3
Reaction time mean AUC0.30.41.10.81.00.31.01.00.30.1-0.3-0.30.4-0.3
Median of all reaction times0.00.10.20.20.40.10.40.40.1-0.0-0.1-0.1-0.0-0.1
Reaction time omissions0.50.60.8-0.8-0.6-0.8-0.7-0.6-0.9-0.80.80.8-0.90.8
Reaction time false alarm rate0.60.91.91.01.30.81.41.30.60.3-0.5-0.80.8-0.8
Reaction time premature initiation rate2.02.73.81.61.11.71.11.11.91.9-1.9-1.71.9-1.7
Reaction time premature initiations1.52.23.51.40.81.60.80.81.81.8-1.9-1.61.8-1.6
Std. dev. reaction times0.91.22.31.31.50.81.51.50.80.5-0.8-0.81.0-0.8
Reaction time trials completed0.10.10.3-0.1-0.5-0.1-0.5-0.50.10.2-0.30.10.20.1
Reaction time trials AUC0.10.10.2-0.0-0.40.0-0.4-0.40.20.3-0.3-0.00.3-0.0
Social response proportion2.52.76.01.00.22.00.10.22.12.4-2.1-2.01.7-2.0
Social responses0.91.23.3-1.4-1.6-0.5-1.8-1.6-0.40.00.40.5-1.10.5
Social time0.50.72.0-1.0-1.4-0.1-1.4-1.4-0.20.30.00.1-0.70.1
Conditioned locomotion0.40.51.10.91.10.21.11.10.3-0.1-0.3-0.20.7-0.2
Cocaine response after cond. corrected0.91.01.60.80.61.30.60.61.11.2-1.2-1.31.0-1.3
Cocaine response after cond. not corrected0.50.50.90.50.31.00.30.30.80.9-0.9-1.00.6-1.0
Cocaine response before conditioning0.70.91.2-1.1-1.0-0.8-1.0-1.0-0.8-0.60.90.8-1.10.8
Saline control response0.40.50.8-0.9-0.8-0.5-0.8-0.8-0.6-0.40.70.5-0.80.5
Condit. Reinf. active minus inactive responses0.81.01.40.90.61.10.60.61.21.2-1.2-1.11.1-1.1
Condit. Reinf. active-inactive response ratio1.21.21.51.10.91.20.90.91.11.1-1.2-1.21.2-1.2
Condit. Reinf. active responses0.30.40.70.60.30.70.30.30.80.8-0.8-0.70.8-0.7
Condit. Reinf. inactive responses0.20.20.4-0.4-0.4-0.7-0.4-0.4-0.5-0.50.50.7-0.40.7
Condit. Reinf. lever presses0.10.20.40.50.7-0.10.70.70.0-0.20.00.10.40.1
Condit. Reinf. lever reinforcers received0.20.30.50.50.30.50.30.30.70.7-0.6-0.50.7-0.5
Pavlov. Cond. lever latency1.01.32.9-1.5-1.7-0.5-1.7-1.7-0.7-0.20.60.5-1.30.5
Pavlov. Cond. magazine entry latency0.81.01.51.21.20.71.21.20.90.7-0.8-0.71.2-0.7
Pavlov. Cond. change in total contacts0.60.81.41.11.20.61.21.20.70.5-0.7-0.61.1-0.6
Pavlov. Cond. index score0.50.61.61.01.30.01.31.30.2-0.2-0.1-0.00.8-0.0
Pavlov. Cond. latency score0.50.71.81.01.3-0.11.31.30.1-0.4-0.00.10.80.1
Pavlov. Cond. lever contacts0.30.40.90.80.90.10.90.90.3-0.0-0.2-0.10.7-0.1
Pavlov. Cond. magazine entry number0.40.51.0-0.9-1.0-0.4-1.0-1.0-0.4-0.20.40.4-0.90.4
Pavlov. Cond. intertrial magazine entries0.70.91.6-1.1-1.3-0.6-1.3-1.3-0.7-0.40.70.6-1.00.6
Pavlov. Cond. lever-magazine prob. diff.0.50.71.71.11.30.11.31.30.3-0.2-0.2-0.10.9-0.1
Pavlov. Cond. response bias0.50.71.51.11.20.41.21.20.60.3-0.5-0.41.0-0.4
Conditioned reinforcement - actives1.01.01.8-1.1-1.2-0.9-1.3-1.2-0.8-0.70.90.9-0.90.9
Conditioned reinforcement - inactives1.92.22.8-1.6-1.4-1.4-1.4-1.4-1.6-1.31.71.4-1.61.4
Conditioned locomotion1.01.22.0-0.8-0.5-1.4-0.7-0.5-1.3-1.31.31.4-0.91.4
Intermittent access intake day 1-15 change1.81.83.5-0.9-0.5-1.6-0.4-0.5-1.7-1.91.81.6-1.11.6
Intermittent access intake escalation1.61.63.6-0.8-0.3-1.5-0.3-0.3-1.6-1.91.71.5-1.01.5
Intermittent access intake escalation 20.60.61.80.00.3-0.90.30.3-0.9-1.30.90.9-0.40.9
Intermitt. access day 1 inactive lever presses0.30.30.60.30.4-0.60.50.4-0.6-0.80.50.60.20.6
Intermitt. access day 15 inactive lever presses0.30.30.40.50.30.60.40.30.60.6-0.5-0.60.7-0.6
Intermitt. access escalation Index0.30.30.7-0.5-0.80.3-0.8-0.80.30.8-0.3-0.3-0.1-0.3
Intermittent access day 1 total infusions2.22.53.2-1.8-1.7-1.6-1.7-1.7-1.5-1.21.51.6-1.61.6
Intermittent access day 15 total infusions6.87.69.6-2.6-2.1-3.1-2.2-2.1-3.1-3.03.13.1-2.73.1
Intermittent access terminal intake (last 3 days)4.95.35.9-2.4-2.2-2.4-2.2-2.2-2.4-2.12.32.4-2.32.4
Intermittent access total infusions3.64.04.9-1.9-1.8-2.2-1.8-1.8-2.1-1.92.12.2-1.82.2
Intermittent access day 1 locomotion3.13.13.9-1.7-1.8-2.0-1.8-1.8-1.8-1.51.82.0-1.42.0
Intermittent access day 15 total locomotion2.52.73.8-1.4-1.1-2.0-1.1-1.1-1.9-1.91.82.0-1.52.0
Intermittent access total locomotion1.71.92.8-1.1-1.3-1.7-1.3-1.3-1.5-1.31.41.7-0.81.7
Intermittent access standard deviation6.26.610.2-2.1-1.5-3.0-1.4-1.5-3.1-3.23.03.0-2.33.0
Cocaine induced anxiety1.82.04.01.81.51.21.51.51.21.0-1.2-1.22.0-1.2
Post-drug Anxiety1.01.11.51.10.91.10.80.91.11.0-1.1-1.11.2-1.1
Baseline Anxiety0.60.71.7-1.1-0.9-0.6-0.9-0.9-0.6-0.60.60.6-1.30.6
Lifetime Intake5.25.86.7-2.4-2.2-2.6-2.2-2.2-2.5-2.32.52.6-2.22.6
Incentive Sensitization - Responses0.20.20.3-0.3-0.5-0.5-0.5-0.5-0.4-0.10.20.5-0.20.5
Incentive Sensitization - Breakpoint0.20.20.2-0.3-0.5-0.5-0.5-0.5-0.4-0.10.20.5-0.20.5
Progressive ratio test 1 active lever presses1.21.21.9-1.4-1.4-0.9-1.3-1.4-0.9-0.71.00.9-1.20.9
Progressive ratio test 1 breakpoint1.41.52.5-1.6-1.6-0.9-1.6-1.6-0.9-0.50.90.9-1.40.9
Progressive ratio test 1 inactive lever presses2.02.12.7-1.3-1.4-1.6-1.3-1.4-1.5-1.41.61.6-1.21.6
Progressive ratio test 2 active lever presses0.91.01.2-1.1-1.1-1.0-1.1-1.1-0.9-0.70.81.0-1.01.0
Progressive ratio test 2 breakpoint0.50.60.8-0.8-0.9-0.8-0.9-0.9-0.7-0.50.60.8-0.60.8
Progressive ratio test 2 inactive lever presses2.73.13.5-1.8-1.7-1.9-1.6-1.7-1.8-1.61.81.9-1.61.9
Total sessions with >9 infusions3.03.24.0-2.0-1.9-1.7-1.9-1.9-1.7-1.52.01.7-1.91.7
Short access day 1 total inactive lever presses0.20.20.5-0.4-0.4-0.5-0.4-0.4-0.6-0.30.70.5-0.20.5
Short access day 10 total inactive lever presses0.10.20.40.50.20.30.30.20.40.5-0.5-0.30.6-0.3
Short access day 1 total infusions4.85.18.1-2.1-1.6-2.5-1.5-1.6-2.6-2.62.82.5-2.22.5
Short access day 10 total infusions2.02.22.5-1.6-1.5-1.6-1.5-1.5-1.5-1.31.41.6-1.41.6
Short access total infusions5.66.27.7-2.5-2.1-2.7-2.1-2.1-2.7-2.52.82.7-2.42.7
Short access day 1 locomotion1.61.72.8-1.1-0.8-1.5-0.8-0.8-1.5-1.61.71.5-1.31.5
Short access day 10 total locomotion1.41.52.4-0.9-0.9-1.5-0.9-0.9-1.4-1.31.41.5-0.71.5
Short access total locomotion1.41.42.1-0.9-0.9-1.4-0.9-0.9-1.4-1.31.41.4-0.81.4
Compulsive drug intake1.71.72.71.20.91.40.80.91.31.5-1.4-1.41.6-1.4
One hour access (0.3 mA shock)1.92.32.6-1.6-1.4-1.5-1.6-1.4-1.5-1.31.51.5-1.51.5
One hour access (shock baseline)3.23.84.2-2.0-1.8-2.0-1.8-1.8-1.9-1.82.02.0-2.12.0
Number of responses in last shaping day0.80.82.0-0.5-0.3-1.0-0.3-0.3-1.1-1.41.41.0-0.61.0
Context. condit. distance diff. score0.70.81.8-1.1-1.4-0.5-1.4-1.4-0.5-0.10.50.5-1.00.5
Locomotion velocity, session 10.90.92.5-1.3-1.60.0-1.6-1.6-0.20.40.2-0.0-1.0-0.0
Locomotion distance, session 10.81.01.5-1.2-1.1-0.8-1.1-1.1-0.9-0.70.90.8-1.20.8
Locomotion velocity, session 20.60.71.00.50.31.00.30.31.01.0-1.0-1.00.7-1.0
Locomotion distance, session 20.10.10.3-0.4-0.50.3-0.5-0.50.20.4-0.2-0.3-0.2-0.3
Locomotion velocity, session 31.51.73.01.71.71.01.71.71.00.6-1.0-1.01.5-1.0
Locomotion distance, session 30.10.10.20.40.40.30.40.40.40.3-0.4-0.30.4-0.3
Stereotopy head waving bouts, day 30.00.00.10.10.00.20.00.00.20.2-0.2-0.20.2-0.2
Stereotopy head waving duration, day 30.60.71.6-0.40.0-1.00.00.0-1.1-1.31.11.0-0.61.0
Locomotion velocity, session 70.10.10.1-0.3-0.2-0.3-0.2-0.2-0.3-0.30.30.3-0.30.3
Locomotion distance, session 70.00.00.10.10.00.10.00.00.20.2-0.2-0.10.2-0.1
Stereotopy head waving bouts, day 70.80.91.6-1.2-1.3-0.7-1.3-1.3-0.7-0.50.70.7-1.10.7
Stereotopy head waving duration, day 70.91.12.0-1.3-1.4-0.7-1.4-1.4-0.8-0.40.80.7-1.20.7
Locomotion velocity, session 80.91.01.6-1.2-1.3-0.9-1.3-1.3-0.8-0.60.80.9-1.10.9
Locomotion distance, session 80.71.02.8-1.3-1.7-0.2-1.7-1.7-0.20.30.20.2-1.00.2
Degree of sensitization distance0.50.50.8-0.9-0.9-0.6-0.9-0.9-0.6-0.40.60.6-0.80.6
Degree of sensitization stereotypy0.60.71.7-1.0-1.3-0.3-1.3-1.3-0.30.10.30.3-0.80.3
Condit. Reinf. active minus inactive responses1.51.72.31.20.91.50.90.91.41.4-1.4-1.51.3-1.5
Condit. Reinf. active-inactive response ratio1.01.01.40.90.81.20.80.81.11.1-1.1-1.21.0-1.2
Condit. Reinf. active responses1.11.41.91.00.81.40.80.81.31.3-1.3-1.41.1-1.4
Condit. Reinf. inactive responses0.00.00.10.20.20.20.20.20.20.1-0.2-0.20.2-0.2
Incentive salience index mean2.22.63.81.41.01.91.01.01.81.9-1.8-1.91.5-1.9
Condit. Reinf. lever presses2.73.76.21.40.82.40.80.82.32.5-2.3-2.41.6-2.4
Time in familiar zone, hab. session 10.20.20.4-0.3-0.1-0.6-0.1-0.1-0.6-0.70.60.6-0.40.6
Time in novel zone, hab. session 10.50.50.80.60.30.80.30.30.80.9-0.8-0.80.7-0.8
Total zone transitions, hab. session 15.37.49.0-2.9-2.6-2.8-2.6-2.6-2.8-2.52.82.8-3.02.8
Total locomotion distance, hab. session 10.30.40.6-0.8-0.7-0.6-0.7-0.7-0.6-0.50.60.6-0.70.6
Locomotion velocity, hab. session 10.40.60.8-0.9-0.8-0.8-0.8-0.8-0.8-0.70.80.8-0.90.8
Time in familiar zone, hab. session 20.30.30.50.40.20.60.20.20.60.7-0.6-0.60.4-0.6
Time in novel zone, hab. session 20.10.10.30.50.60.10.60.60.1-0.1-0.1-0.10.4-0.1
Total zone transitions, hab. session 22.22.94.1-2.0-1.9-1.5-1.9-1.9-1.6-1.31.61.5-2.01.5
Total locomotion distance, hab. session 20.40.50.7-0.9-0.8-0.6-0.8-0.8-0.7-0.50.70.6-0.80.6
Locomotion velocity, hab. session 20.50.60.9-0.9-0.8-0.7-0.8-0.8-0.8-0.60.80.7-0.90.7
Novel to familiar place preference ratio0.10.10.3-0.2-0.0-0.5-0.0-0.0-0.4-0.60.40.5-0.20.5
Novelty place preference0.00.00.0-0.0-0.0-0.1-0.0-0.0-0.1-0.20.10.1-0.00.1
Time in novel zone, NPP test0.00.00.00.0-0.10.0-0.1-0.10.10.0-0.1-0.00.0-0.0
Total zone transitions, NPP test3.24.66.0-2.4-2.1-2.0-2.1-2.1-2.2-1.82.22.0-2.42.0
Total locomotion distance, NPP test0.40.50.9-0.6-0.3-0.8-0.3-0.3-0.9-1.00.90.8-0.80.8
Locomotion velocity, NPP test0.40.51.2-0.40.0-0.80.00.0-1.0-1.11.00.8-0.60.8
Pavlov. Cond. lever latency2.93.74.6-1.9-1.6-2.1-1.6-1.6-2.0-1.92.02.1-1.92.1
Pavlov. Cond. magazine entry latency4.65.97.82.21.82.81.81.82.72.7-2.7-2.82.4-2.8
Pavlov. Cond. change in total contacts2.52.73.21.81.81.61.81.81.51.2-1.5-1.61.7-1.6
Pavlov. Cond. index score3.24.15.61.81.42.41.41.42.32.3-2.3-2.41.9-2.4
Pavlov. Cond. latency score3.64.66.41.91.42.51.41.42.42.5-2.4-2.52.0-2.5
Pavlov. Cond. lever contacts2.22.63.51.51.31.91.31.31.71.7-1.7-1.91.5-1.9
Pavlov. Cond. magazine entry number2.43.03.7-1.7-1.4-1.9-1.4-1.4-1.8-1.71.81.9-1.71.9
Pavlov. Cond. intertrial magazine entries3.84.55.2-2.1-1.8-2.3-1.8-1.8-2.3-2.12.32.3-2.22.3
Pavlov. Cond. lever-magazine prob. diff.3.03.85.11.81.42.31.41.42.12.1-2.1-2.31.9-2.3
Pavlov. Cond. response bias2.93.54.61.71.52.21.51.52.02.0-2.0-2.21.8-2.2
Bone: apparent density0.30.51.2-0.3-0.70.6-0.7-0.70.71.1-0.7-0.60.0-0.6
Bone surface0.61.12.4-1.3-1.5-0.7-1.5-1.5-0.6-0.30.60.7-1.10.7
Bone volume1.01.73.2-1.6-1.8-0.9-1.8-1.8-0.9-0.50.90.9-1.40.9
Bone: connectivity density0.30.51.4-0.8-1.20.2-1.2-1.20.20.6-0.2-0.2-0.5-0.2
Bone: cortical apparent density0.81.12.01.31.40.81.41.40.70.4-0.7-0.81.1-0.8
Bone: cortical area0.10.20.40.10.4-0.40.40.4-0.5-0.60.50.4-0.00.4
Bone: cortical porosity2.42.63.41.41.01.81.01.01.81.8-1.8-1.81.7-1.8
Bone: cortical porosity2.12.32.91.41.11.71.11.11.71.6-1.7-1.71.6-1.7
Bone: cortical thickness1.72.94.52.02.11.42.12.11.30.9-1.3-1.41.9-1.4
Bone: cortical thickness4.85.66.42.52.22.52.22.22.42.2-2.4-2.52.5-2.5
Bone: cortical tissue density0.70.91.71.21.30.71.31.30.70.4-0.7-0.71.0-0.7
Bone: elastic displacement0.10.20.40.40.6-0.10.60.6-0.2-0.40.20.10.30.1
Bone: elastic work0.81.02.21.21.50.61.51.50.50.1-0.5-0.61.1-0.6
Bone: endosteal estimation3.88.29.5-2.9-2.3-3.1-2.3-2.3-3.1-2.93.13.1-3.13.1
Bone: endosteal perimeter3.98.09.6-2.9-2.4-3.0-2.4-2.4-3.0-2.73.03.0-3.13.0
Bone: final force0.61.01.2-1.1-1.0-1.0-1.0-1.0-1.0-0.91.01.0-1.11.0
Bone: final moment0.71.21.4-1.1-1.0-1.1-1.0-1.0-1.1-1.01.11.1-1.21.1
Bone: marrow area3.78.09.3-2.8-2.3-3.0-2.3-2.3-3.1-2.83.13.0-3.13.0
Bone: maximum diameter1.01.92.8-1.2-0.7-1.6-0.7-0.7-1.6-1.71.61.6-1.41.6
Bone: maximum force0.71.31.5-1.2-1.0-1.2-1.0-1.0-1.2-1.01.21.2-1.21.2
Bone: maximum moment0.91.61.9-1.3-1.0-1.4-1.0-1.0-1.4-1.31.41.4-1.31.4
Bone: minimum diameter2.44.45.1-2.2-1.9-2.2-1.9-1.9-2.2-2.02.22.2-2.32.2
Bone: periosteal estimation1.93.84.9-1.8-1.4-2.2-1.4-1.4-2.2-2.12.22.2-2.12.2
Bone: periosteal perimeter1.22.02.6-1.3-1.0-1.6-1.0-1.0-1.6-1.51.61.6-1.51.6
Bone: post-yield work0.20.30.8-0.7-0.9-0.1-0.9-0.9-0.00.30.00.1-0.50.1
Bone: stiffness1.21.84.1-1.7-2.0-0.7-2.0-2.0-0.7-0.20.70.7-1.50.7
Bone: tissue strength0.20.20.4-0.20.1-0.60.10.1-0.5-0.60.50.6-0.30.6
Bone: trabecular number0.40.71.70.3-0.11.0-0.1-0.11.11.3-1.1-1.00.6-1.0
Bone: trabecular spacing0.30.40.9-0.3-0.1-0.8-0.1-0.1-0.8-1.00.80.8-0.50.8
Bone: trabecular thickness0.10.10.2-0.3-0.5-0.0-0.5-0.50.10.3-0.10.0-0.20.0
Bone: trabecular tissue density1.11.53.51.51.90.71.91.90.60.2-0.6-0.71.2-0.7
Breakpoint value in progressive ratio session0.20.20.4-0.6-0.60.3-0.6-0.60.20.5-0.1-0.3-0.5-0.3
Distance traveled before self-admin0.80.81.6-0.6-0.1-1.1-0.1-0.1-1.1-1.31.21.1-1.01.1
Distance traveled after self-admin7.68.410.6-3.0-2.7-3.0-2.6-2.7-2.9-2.73.03.0-3.33.0
Delta time in closed arm before/after self-admin0.90.91.7-1.1-0.7-0.8-0.7-0.7-1.0-1.01.20.8-1.30.8
Delta time in open arm before/after self-admin0.80.71.2-1.0-1.0-0.8-1.1-1.0-0.7-0.50.60.8-0.90.8
Diff in mean of infusions in LGA sessions0.50.61.40.30.00.9-0.00.00.91.2-1.1-0.90.6-0.9
Extinction: sum of active levers before priming0.50.51.4-0.9-1.20.1-1.1-1.20.10.40.0-0.1-0.7-0.1
Active lever presses in extinction session 60.70.71.4-1.2-1.1-0.5-1.1-1.1-0.5-0.30.70.5-1.10.5
Delta distance traveled before/after self-admin3.43.76.0-2.2-2.5-1.6-2.4-2.5-1.6-1.11.61.6-1.91.6
Delta ambulatory time before/after self-admin2.22.34.1-1.7-2.0-1.3-2.0-2.0-1.3-0.81.21.3-1.51.3
Time in closed arm before self-admin1.01.12.40.70.21.20.30.21.31.6-1.3-1.21.1-1.2
Time in closed arm after self-admin0.00.00.10.20.20.20.30.20.20.20.0-0.20.3-0.2
Time in open arm before self-admin0.50.51.50.81.20.11.21.2-0.1-0.50.1-0.10.4-0.1
Time in open arm after self-admin1.11.22.5-0.8-0.4-1.3-0.5-0.4-1.3-1.61.31.3-1.11.3
Sum of active levers in priming session hrs 5-60.60.61.6-0.1-0.41.0-0.5-0.41.01.3-0.9-1.00.2-1.0
Time to tail flick, vehicle, before self-admin0.30.31.1-0.1-0.30.7-0.2-0.30.61.0-0.8-0.70.2-0.7
Time to tail flick, vehicle, after self-admin0.10.10.2-0.4-0.4-0.3-0.4-0.4-0.4-0.30.40.3-0.40.3
Time to tail flick, test, before self-admin4.94.86.22.21.72.31.61.72.42.3-2.4-2.32.5-2.3
Time to tail flick, test, after self-admin1.21.31.71.00.81.30.90.81.21.2-1.2-1.31.1-1.3
Delta time to tail flick, vehicle, before/after SA1.31.22.5-0.7-0.4-1.3-0.5-0.4-1.3-1.61.51.3-0.91.3
Delta time to tail flick, test, before/after SA2.01.82.6-1.4-1.0-1.4-0.9-1.0-1.5-1.51.51.4-1.61.4
Ambulatory time before self-admin0.30.30.6-0.20.2-0.60.20.2-0.5-0.80.70.6-0.60.6
Ambulatory time after self-admin3.03.34.3-2.1-2.1-1.7-2.0-2.1-1.6-1.31.71.7-2.01.7
Total heroin consumption0.91.13.3-0.1-0.61.2-0.6-0.61.31.8-1.2-1.20.4-1.2
Area under the delay curve0.10.10.2-0.10.1-0.30.10.1-0.4-0.40.40.3-0.20.3
Delay disc. indifference point, 0s delay2.12.33.0-1.7-1.5-1.4-1.5-1.5-1.5-1.31.51.4-1.71.4
Delay disc. indifference point, 16s delay0.70.71.0-0.7-0.4-0.9-0.4-0.4-1.0-1.01.00.9-0.90.9
Delay disc. indifference point, 2s delay0.10.10.20.40.50.10.50.50.2-0.0-0.2-0.10.3-0.1
Delay disc. indifference point, 24s delay0.90.91.11.01.00.91.01.00.80.7-0.8-0.91.0-0.9
Delay disc. indifference point, 4s delay0.50.50.7-0.8-0.7-0.7-0.7-0.7-0.8-0.70.80.7-0.80.7
Delay disc. indifference point, 8s delay0.00.00.0-0.1-0.0-0.1-0.0-0.0-0.1-0.10.10.1-0.10.1
Delay discount exponential model param0.00.00.1-0.2-0.3-0.0-0.3-0.30.00.1-0.00.0-0.10.0
Delay discount hyperbolic model param0.00.00.0-0.1-0.20.1-0.2-0.20.10.2-0.1-0.10.0-0.1
Fecal boli incidents, locomotor time 10.40.40.50.70.60.70.60.70.60.6-0.6-0.70.6-0.7
Change in fecal boli incidents, locomotor task0.60.60.90.90.80.70.80.80.70.6-0.7-0.71.0-0.7
Time >=10cm from walls, locomotor time 10.50.50.50.70.70.70.70.60.70.7-0.7-0.70.7-0.7
Bouts of movement, locomotor time 10.91.01.20.90.71.10.70.81.11.1-1.1-1.11.1-1.1
Total resting periods, locomotor time 12.32.53.21.61.41.71.41.41.61.6-1.6-1.71.8-1.7
Rest time, locomotor task time 10.50.50.90.91.00.51.00.90.50.3-0.5-0.50.8-0.5
Distance moved, locomotor task time 11.11.31.6-1.3-1.2-1.0-1.2-1.2-1.1-0.91.11.0-1.31.0
Vertical activity count, locomotor time 11.11.11.5-1.2-1.2-1.0-1.2-1.2-0.9-0.70.91.0-1.21.0
Time >=10cm from walls, locomotor time 20.90.91.11.01.00.91.00.90.90.8-0.9-0.91.0-0.9
Bouts of movement, locomotor time 21.41.61.81.31.21.31.21.21.21.2-1.2-1.31.3-1.3
Total resting periods, locomotor time 21.01.11.21.10.91.10.90.91.11.1-1.1-1.11.1-1.1
Rest time, locomotor task time 21.01.22.01.21.11.01.11.11.00.8-1.0-1.01.4-1.0
Distance moved, locomotor task time 22.42.83.6-1.7-1.4-1.7-1.4-1.4-1.7-1.71.71.7-1.91.7
Vertical activity count, locomotor time 20.80.91.2-1.0-0.9-0.9-0.9-0.9-0.9-0.80.90.9-1.10.9
Weight adjusted by age2.73.14.4-2.0-1.9-1.6-1.9-1.9-1.4-1.31.71.6-2.11.6
Seeking ratio, delayed vs. immediate footshock0.40.41.00.71.00.51.01.00.40.1-0.4-0.50.4-0.5
Locomotion in novel chamber1.62.04.6-0.6-0.2-2.0-0.3-0.2-1.6-2.11.42.0-1.02.0
Locomotion in novel chamber post-restriction0.20.30.50.60.70.30.70.70.40.2-0.4-0.30.6-0.3
Progressive ratio0.80.91.8-0.9-0.6-0.9-0.6-0.6-1.0-1.11.10.9-1.30.9
Food seeking constrained by brief footshock0.10.10.30.30.50.40.50.50.30.0-0.4-0.40.1-0.4
Seeking ratio, punishment vs. effort1.21.52.31.31.01.21.01.01.21.1-1.4-1.21.5-1.2
Run reversals in cocaine runway, females0.10.10.20.40.30.00.30.30.10.1-0.1-0.00.4-0.0
Run reversals in cocaine runway, males2.72.63.7-1.4-1.0-1.8-1.0-1.0-1.8-1.91.81.8-1.71.8
Latency to leave start box in cocaine runway0.20.20.40.20.40.60.40.40.50.4-0.3-0.60.2-0.6
Latency to leave start box in cocaine runway, F0.40.40.90.20.31.00.30.30.80.8-0.6-1.00.2-1.0
Latency to leave start box in cocaine runway, M0.20.20.3-0.5-0.5-0.5-0.5-0.5-0.5-0.40.50.5-0.50.5
Cd content in liver1.01.11.8-1.2-1.3-0.9-1.2-1.3-0.9-0.70.90.9-1.20.9
Co content in liver0.20.20.4-0.5-0.6-0.3-0.6-0.6-0.4-0.30.30.3-0.40.3
Cu content in liver3.23.94.52.11.82.01.91.82.01.8-2.0-2.02.1-2.0
Fe content in liver0.30.40.90.1-0.20.8-0.2-0.20.70.9-0.8-0.80.3-0.8
K content in liver0.30.30.70.1-0.20.6-0.2-0.20.70.9-0.6-0.60.1-0.6
Mg content in liver0.00.00.0-0.00.1-0.20.10.1-0.1-0.10.20.2-0.10.2
Mn content in liver1.92.22.81.41.21.61.21.21.71.6-1.6-1.61.5-1.6
Na content in liver0.20.20.3-0.20.1-0.50.10.1-0.5-0.60.50.5-0.30.5
Rb content in liver0.81.11.4-1.1-1.0-1.0-1.0-1.0-1.0-0.81.01.0-1.21.0
Se content in liver0.81.01.81.21.30.81.31.30.70.5-0.8-0.81.1-0.8
Sr content in liver1.71.52.2-1.4-1.5-1.1-1.5-1.5-1.1-0.91.11.1-1.21.1
Zn content in liver0.10.10.30.50.50.30.50.50.30.1-0.3-0.30.5-0.3