Scara3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016177 0.02 0.02 9.3e-03 0.01 0 -0 -0 2.4e-02 1.6e-01 3.8e-01 4.9e-01
2 Adipose mRNA stability ENSRNOG00000016177 0.04 0.03 1.1e-03 0 0.01 0.01 0 1.1e-01 9.6e-03 1.5e-02 7.9e-02
3 BLA gene expression ENSRNOG00000016177 0.73 0.13 0.0e+00 0.48 0.4 0.45 0.46 2.0e-28 6.9e-23 2.7e-26 6.7e-27
4 Brain gene expression ENSRNOG00000016177 0.44 0.22 0.0e+00 0.24 0.26 0.24 0.25 9.2e-22 5.0e-24 4.8e-22 8.2e-23
5 Brain intron excision ratio chr15:40151061:40152473 0.08 0.06 2.1e-05 0.05 0.06 0.06 0.06 1.5e-05 4.7e-06 5.6e-06 5.7e-06
6 Brain intron excision ratio chr15:40151276:40152473 0.53 0.23 3.5e-06 0.06 0.07 0.08 0.07 1.7e-06 1.6e-07 4.2e-08 6.6e-07
7 Brain mRNA stability ENSRNOG00000016177 0.34 0.13 0.0e+00 0.31 0.33 0.33 0.33 2.2e-29 4.6e-31 6.6e-31 1.5e-31
8 IL gene expression ENSRNOG00000016177 0.26 0.15 6.6e-04 0.13 0.11 0.08 0.09 5.9e-04 1.3e-03 5.2e-03 4.3e-03
9 LHb gene expression ENSRNOG00000016177 0.54 0.15 2.9e-10 0.24 0.25 0.22 0.23 2.1e-06 1.2e-06 7.6e-06 3.2e-06
10 NAcc gene expression ENSRNOG00000016177 0.29 0.11 0.0e+00 0.26 0.26 0.25 0.27 1.5e-19 3.3e-19 8.8e-19 5.8e-20
11 OFC gene expression ENSRNOG00000016177 0.43 0.17 1.1e-06 0.22 0.16 0.23 0.24 7.2e-06 1.2e-04 4.4e-06 2.0e-06
12 PL gene expression ENSRNOG00000016177 0.31 0.13 0.0e+00 0.18 0.15 0.22 0.15 2.2e-13 9.2e-12 1.1e-16 1.9e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.41.22.01.20.1-1.0-0.61.2-1.4-1.4-0.8-1.4-0.9-0.8-1.4
BMI without tail0.40.92.5-0.41.60.81.4-0.81.10.21.00.20.91.00.2
Body weight0.20.71.40.9-1.2-1.0-0.80.9-0.3-0.6-1.0-0.6-1.0-1.0-0.6
Epididymis fat weight1.02.35.7-1.31.11.51.7-1.52.41.21.51.31.51.61.4
Glucose0.60.92.71.11.0-0.50.10.8-0.8-1.7-0.5-1.3-0.5-0.4-1.4
Heart weight0.20.22.40.4-0.2-0.30.20.11.5-0.1-0.30.0-0.2-0.1-0.0
Left kidney weight1.13.04.52.0-1.5-2.1-1.31.80.4-1.8-2.1-1.5-2.0-1.9-1.6
Right kidney weight0.20.73.9-0.0-1.6-0.5-0.1-0.12.00.4-0.60.8-0.4-0.40.5
Tail length0.72.16.7-1.10.11.11.5-1.52.61.61.11.61.11.21.5
Length with tail0.10.42.6-0.1-1.6-0.3-0.4-0.10.70.7-0.40.7-0.3-0.40.7
Length without tail1.83.97.11.6-2.7-2.1-2.52.0-2.0-1.2-2.1-1.2-2.2-2.2-1.1
Liver weight, left4.87.79.72.9-1.4-3.1-2.63.1-2.3-3.0-3.0-2.9-3.0-2.8-2.8
Liver weight, right2.33.84.82.2-1.0-2.1-2.02.1-1.4-2.1-2.0-2.0-2.1-1.9-2.1
Parametrial fat weight3.46.78.7-2.92.22.92.7-2.81.32.32.92.42.92.92.3
Retroperitoneal fat weight0.51.72.8-1.01.51.41.7-1.21.50.81.40.81.41.41.0
Intraocular pressure1.21.72.5-1.40.41.50.9-1.50.81.61.31.51.41.31.6
Extensor digitorum longus weight8.634.740.66.0-4.1-6.1-6.26.4-5.8-5.6-6.1-5.7-6.2-6.3-5.8
Soleus weight0.51.43.91.2-0.2-1.0-1.11.2-2.0-1.2-1.0-1.4-1.0-1.1-1.2
Tibialis anterior weight6.321.826.34.6-3.6-4.9-5.15.0-4.3-4.2-5.0-4.4-5.0-5.1-4.4
Tibia length0.72.15.0-1.6-1.80.40.2-1.22.22.10.32.20.40.51.8
Number of licking bursts0.10.20.9-0.00.90.40.5-0.20.3-0.20.4-0.20.40.4-0.2
Food consumed during 24 hour testing period0.60.71.30.8-1.1-1.1-0.60.71.0-0.4-1.1-0.3-1.1-0.9-0.7
Times rat made contact with spout0.10.10.60.10.50.10.4-0.00.8-0.30.0-0.10.00.2-0.3
Mean time between licks in bursts3.95.56.5-2.41.32.52.1-2.61.92.52.62.42.52.52.5
Mean num. licks in bursts0.10.10.30.2-0.5-0.3-0.20.20.2-0.1-0.4-0.0-0.4-0.3-0.1
Std. dev. time between licks in bursts4.85.810.4-2.9-0.22.21.3-2.72.03.12.33.22.22.22.9
Water consumed over 24 hours1.01.21.81.2-1.2-1.2-1.31.1-0.2-0.9-1.2-0.8-1.3-1.2-1.0
Indifference point 0 sec1.82.97.4-2.1-1.71.00.4-1.71.82.40.92.70.91.02.0
Indifference point AUC1.72.04.71.70.5-1.1-0.81.6-0.7-2.1-1.0-2.2-1.1-1.0-2.1
Indifference point function ln k0.40.51.6-0.7-1.00.3-0.1-0.70.21.10.21.30.30.31.0
Indifference point function log k0.40.51.6-0.7-1.00.3-0.1-0.70.21.10.21.30.30.31.0
Delay discounting total patch changes 0 sec1.42.26.0-1.7-1.90.70.2-1.41.62.20.62.40.60.71.7
Delay discounting total patch changes 12 sec0.20.30.6-0.7-0.70.3-0.0-0.50.30.70.40.80.30.40.4
Delay discounting total patch changes 18 sec0.20.20.8-0.20.20.40.5-0.50.90.40.50.50.40.50.2
Delay discounting total patch changes 24 sec0.30.32.3-0.5-1.5-0.2-0.6-0.1-0.10.6-0.20.8-0.3-0.20.2
Delay discounting total patch changes 6 sec0.10.10.3-0.5-0.20.30.3-0.40.50.40.30.50.30.30.4
Delay discounting time to switch 0 sec1.01.62.2-1.50.61.31.0-1.40.31.41.41.41.41.31.5
Delay discounting water rate 0 sec0.50.81.30.8-1.1-1.0-0.90.80.4-0.6-1.0-0.6-1.1-1.0-0.8
Delay discounting water rate 12 sec0.40.61.60.6-1.3-0.8-0.90.7-0.0-0.3-0.9-0.2-0.9-0.8-0.4
Delay discounting water rate 18 sec3.95.16.42.4-1.5-2.5-2.02.5-1.3-2.5-2.5-2.2-2.5-2.4-2.5
Delay discounting water rate 24 sec0.40.61.41.20.4-0.7-0.20.80.1-1.0-0.7-1.0-0.7-0.6-0.9
Delay discounting water rate 6 sec1.92.84.61.8-2.1-1.9-1.91.70.3-1.0-1.9-1.1-2.0-1.9-1.4
Locomotor activity1.21.811.10.1-3.3-1.3-1.70.70.70.5-1.30.6-1.2-1.30.1
Locomotor testing distance1.72.96.7-2.1-2.30.7-0.1-1.41.82.50.72.60.70.72.0
Locomotor testing rearing3.04.711.2-2.7-2.51.1-0.0-2.01.93.31.13.31.11.12.9
Light reinforcement 11.12.02.7-1.31.41.51.6-1.41.61.11.51.21.41.61.2
Light reinforcement 20.60.84.20.32.00.71.2-0.20.9-0.60.7-0.50.70.8-0.3
Reaction time number correct0.10.10.40.20.60.30.00.0-0.6-0.10.1-0.20.30.00.1
Reaction time mean minus median0.10.20.6-0.1-0.8-0.3-0.60.1-0.80.5-0.20.3-0.2-0.20.4
Reaction time mean minus median AUC0.10.10.5-0.1-0.4-0.2-0.40.0-0.70.5-0.10.2-0.1-0.10.4
Reaction time num false alarms0.20.20.8-0.7-0.60.2-0.1-0.4-0.10.90.20.70.30.20.6
Reaction time num false alarms AUC0.10.10.4-0.2-0.7-0.2-0.30.0-0.30.5-0.30.3-0.1-0.20.2
Reaction time trials correct on left0.10.10.40.20.60.30.00.0-0.6-0.10.1-0.20.30.00.1
Reaction time trials on left0.10.10.50.10.70.30.1-0.1-0.60.00.2-0.20.40.10.2
Reaction time mean0.10.10.20.3-0.3-0.4-0.30.3-0.10.1-0.3-0.2-0.3-0.30.2
Reaction time mean AUC0.10.20.40.3-0.7-0.6-0.50.4-0.40.1-0.5-0.2-0.5-0.50.2
Median of all reaction times0.10.10.20.5-0.1-0.3-0.00.40.0-0.0-0.4-0.4-0.3-0.40.2
Reaction time omissions1.82.53.5-1.91.01.61.5-1.7-0.21.81.61.71.71.61.8
Reaction time false alarm rate0.00.10.3-0.4-0.6-0.1-0.0-0.10.30.3-0.10.3-0.1-0.00.1
Reaction time premature initiation rate0.40.61.10.8-0.3-0.9-0.80.8-0.1-1.1-0.7-0.9-0.8-0.7-0.9
Reaction time premature initiations0.40.61.10.80.0-0.7-0.70.8-0.4-1.1-0.6-1.0-0.6-0.7-0.9
Std. dev. reaction times0.00.10.20.1-0.3-0.3-0.20.2-0.40.1-0.2-0.1-0.2-0.20.1
Reaction time trials completed0.10.10.50.10.70.30.1-0.1-0.60.00.2-0.20.40.10.2
Reaction time trials AUC0.10.10.40.10.60.30.1-0.0-0.60.00.2-0.20.40.10.2
Social response proportion0.60.63.5-0.11.90.80.8-0.4-0.8-0.10.8-0.20.80.70.3
Social responses4.35.57.3-2.21.92.62.0-2.51.62.52.52.32.62.62.7
Social time0.40.61.2-1.1-0.60.60.2-0.70.50.90.51.10.50.51.1
Conditioned locomotion0.40.51.2-0.51.11.00.6-0.5-0.60.20.90.20.80.80.4
Cocaine response after cond. corrected0.50.62.50.61.60.30.20.4-1.2-0.90.2-1.00.20.1-0.7
Cocaine response after cond. not corrected0.30.41.60.11.20.40.30.1-1.2-0.50.4-0.60.40.3-0.3
Cocaine response before conditioning0.60.81.9-1.3-1.00.40.3-0.90.61.30.41.40.40.41.1
Saline control response0.20.20.6-0.5-0.80.1-0.1-0.40.60.70.00.80.10.10.6
Condit. Reinf. active minus inactive responses0.30.40.9-0.90.00.70.3-0.70.70.70.60.80.60.60.6
Condit. Reinf. active-inactive response ratio0.10.10.30.20.2-0.2-0.30.4-0.3-0.6-0.3-0.6-0.3-0.3-0.5
Condit. Reinf. active responses0.81.01.6-1.20.21.00.8-1.21.31.01.01.21.01.00.9
Condit. Reinf. inactive responses2.63.24.3-1.90.61.71.6-2.01.62.01.82.11.81.81.9
Condit. Reinf. lever presses0.20.31.8-0.2-1.3-0.5-0.4-0.00.40.5-0.40.6-0.4-0.40.3
Condit. Reinf. lever reinforcers received0.40.51.1-0.9-0.00.70.5-0.81.00.70.70.90.60.70.6
Pavlov. Cond. lever latency1.31.83.5-1.21.91.61.5-1.30.60.81.60.81.61.50.8
Pavlov. Cond. magazine entry latency0.30.31.20.5-1.1-0.7-0.50.40.60.1-0.70.0-0.7-0.6-0.1
Pavlov. Cond. change in total contacts2.73.85.22.0-2.3-2.3-2.32.0-1.0-1.4-2.2-1.3-2.3-2.2-1.5
Pavlov. Cond. index score1.21.53.91.1-2.0-1.5-1.51.2-0.1-0.4-1.5-0.5-1.5-1.4-0.6
Pavlov. Cond. latency score0.81.13.60.8-1.9-1.2-1.30.90.1-0.2-1.2-0.2-1.3-1.2-0.3
Pavlov. Cond. lever contacts1.31.85.11.0-2.3-1.7-1.61.2-0.3-0.3-1.6-0.4-1.6-1.5-0.7
Pavlov. Cond. magazine entry number0.20.21.2-0.20.90.30.20.0-1.1-0.50.3-0.40.30.2-0.2
Pavlov. Cond. intertrial magazine entries7.39.412.5-3.51.93.33.0-3.42.23.03.23.13.33.23.0
Pavlov. Cond. lever-magazine prob. diff.1.21.63.61.2-1.9-1.5-1.51.2-0.1-0.5-1.5-0.6-1.5-1.4-0.7
Pavlov. Cond. response bias1.41.95.51.2-2.3-1.7-1.61.2-0.2-0.3-1.6-0.4-1.6-1.6-0.7
Conditioned reinforcement - actives1.41.43.2-1.01.41.21.8-1.31.40.61.10.81.31.20.6
Conditioned reinforcement - inactives2.02.27.3-1.50.41.21.6-1.52.71.41.21.51.21.31.4
Conditioned locomotion0.50.61.8-0.50.90.71.4-0.71.30.10.60.20.70.70.1
Intermittent access intake day 1-15 change0.40.42.2-0.40.20.50.3-0.51.50.40.50.50.40.60.5
Intermittent access intake escalation0.10.10.7-0.20.10.2-0.0-0.20.80.10.30.20.20.30.2
Intermittent access intake escalation 20.00.00.3-0.1-0.10.0-0.2-0.10.50.20.10.2-0.00.10.3
Intermitt. access day 1 inactive lever presses0.70.71.3-0.91.00.90.9-0.80.20.70.90.50.90.91.1
Intermitt. access day 15 inactive lever presses0.10.10.20.3-0.2-0.5-0.40.4-0.1-0.3-0.5-0.4-0.4-0.4-0.0
Intermitt. access escalation Index0.00.00.1-0.20.20.00.1-0.1-0.20.30.0-0.00.1-0.00.0
Intermittent access day 1 total infusions0.60.61.60.90.3-0.60.30.60.9-1.2-0.7-1.0-0.6-0.6-1.3
Intermittent access day 15 total infusions0.30.31.50.30.80.10.50.01.2-0.60.1-0.40.10.2-0.5
Intermittent access terminal intake (last 3 days)0.80.82.21.10.4-0.6-0.10.90.6-1.5-0.7-1.2-0.7-0.7-1.4
Intermittent access total infusions0.50.52.00.41.20.11.00.01.4-0.90.0-0.60.10.1-0.8
Intermittent access day 1 locomotion0.40.42.4-0.40.30.41.1-0.51.50.10.50.30.40.5-0.0
Intermittent access day 15 total locomotion0.40.43.00.50.70.10.70.01.7-0.50.1-0.30.00.3-0.3
Intermittent access total locomotion0.40.54.30.00.30.20.9-0.22.1-0.20.30.00.20.3-0.2
Intermittent access standard deviation0.70.81.11.0-0.6-1.0-0.90.90.6-0.9-1.1-0.7-1.0-0.9-0.9
Cocaine induced anxiety0.50.62.80.0-1.7-0.7-0.80.3-1.00.2-0.80.3-0.7-0.80.0
Post-drug Anxiety2.02.33.7-1.80.31.51.0-1.70.61.81.51.91.51.51.9
Baseline Anxiety2.72.93.5-1.71.21.81.5-1.81.91.61.91.71.81.91.6
Lifetime Intake0.40.43.00.30.80.11.0-0.11.7-0.5-0.0-0.40.10.1-0.5
Incentive Sensitization - Responses0.50.53.00.7-0.5-0.7-0.00.51.7-0.6-0.6-0.5-0.7-0.4-0.5
Incentive Sensitization - Breakpoint0.50.54.30.5-0.4-0.60.10.42.1-0.4-0.5-0.3-0.6-0.3-0.4
Progressive ratio test 1 active lever presses1.01.02.61.31.0-0.60.20.9-0.1-1.6-0.7-1.5-0.6-0.7-1.6
Progressive ratio test 1 breakpoint1.01.02.61.21.2-0.50.20.80.2-1.6-0.6-1.5-0.5-0.6-1.5
Progressive ratio test 1 inactive lever presses0.70.71.5-0.71.00.81.0-0.91.20.60.70.60.90.80.7
Progressive ratio test 2 active lever presses0.80.92.41.11.0-0.50.50.61.5-1.3-0.5-1.2-0.5-0.4-1.2
Progressive ratio test 2 breakpoint0.80.93.51.10.7-0.60.50.71.9-1.2-0.6-1.1-0.6-0.4-1.1
Progressive ratio test 2 inactive lever presses0.30.43.20.30.4-0.10.80.01.8-0.4-0.1-0.3-0.10.0-0.3
Total sessions with >9 infusions0.70.81.8-0.61.01.01.1-0.91.30.70.90.50.90.90.7
Short access day 1 total inactive lever presses0.91.04.00.90.6-0.50.80.62.0-1.4-0.6-1.1-0.5-0.4-1.2
Short access day 10 total inactive lever presses0.60.71.3-0.81.10.90.8-0.80.60.60.80.50.90.80.8
Short access day 1 total infusions0.30.30.90.30.90.10.90.10.8-0.5-0.0-0.70.1-0.0-0.4
Short access day 10 total infusions0.60.71.40.9-0.8-0.9-0.40.70.8-0.7-1.0-0.6-0.9-0.9-1.2
Short access total infusions0.40.42.90.50.1-0.30.50.21.7-0.4-0.5-0.4-0.3-0.4-0.6
Short access day 1 locomotion0.20.20.60.3-0.8-0.6-0.40.30.20.1-0.6-0.1-0.6-0.6-0.1
Short access day 10 total locomotion0.70.82.7-0.80.00.71.0-0.81.60.90.80.90.70.80.9
Short access total locomotion0.70.72.5-0.8-0.10.60.8-0.81.60.80.60.90.60.70.8
Compulsive drug intake0.40.40.8-0.8-0.10.50.5-0.7-0.80.90.40.70.60.40.6
One hour access (0.3 mA shock)0.20.21.00.50.2-0.30.40.21.0-0.5-0.5-0.4-0.2-0.3-0.8
One hour access (shock baseline)0.40.51.50.80.2-0.40.10.51.2-0.9-0.5-0.8-0.4-0.4-0.9
Number of responses in last shaping day0.40.41.60.2-1.3-0.7-0.90.4-0.70.1-0.70.1-0.7-0.6-0.1
Context. condit. distance diff. score1.61.910.1-0.13.21.41.9-0.70.7-0.51.4-0.51.41.4-0.0
Locomotion velocity, session 10.30.30.9-0.8-0.50.5-0.2-0.5-0.10.90.50.80.40.30.7
Locomotion distance, session 10.60.82.1-0.9-1.50.3-0.5-0.70.91.40.41.30.20.30.8
Locomotion velocity, session 20.30.31.4-0.6-1.2-0.0-0.6-0.30.10.90.00.8-0.0-0.00.4
Locomotion distance, session 20.91.33.6-1.3-1.70.4-0.6-0.91.01.90.41.70.40.41.2
Locomotion velocity, session 31.21.42.31.5-0.0-1.1-0.91.3-1.2-1.4-1.1-1.5-1.1-1.1-1.2
Locomotion distance, session 30.20.20.70.60.6-0.2-0.10.4-0.2-0.8-0.2-0.7-0.2-0.2-0.7
Stereotopy head waving bouts, day 30.20.31.10.3-0.7-0.4-0.70.4-1.10.2-0.4-0.2-0.4-0.40.2
Stereotopy head waving duration, day 31.61.92.81.3-1.6-1.5-1.71.5-1.2-0.8-1.5-1.1-1.6-1.6-0.8
Locomotion velocity, session 72.93.213.4-0.63.71.92.6-1.31.20.01.90.01.92.00.6
Locomotion distance, session 74.25.312.4-1.73.52.63.1-2.21.61.12.61.12.62.61.3
Stereotopy head waving bouts, day 71.41.62.61.2-1.6-1.5-1.61.3-0.6-0.7-1.4-0.9-1.5-1.4-0.9
Stereotopy head waving duration, day 72.73.34.61.8-1.7-2.0-2.12.0-1.3-1.5-1.9-1.6-2.1-2.0-1.4
Locomotion velocity, session 80.20.20.50.60.5-0.2-0.20.40.3-0.6-0.2-0.7-0.2-0.2-0.6
Locomotion distance, session 80.71.12.3-0.71.21.11.0-1.01.50.71.20.61.11.20.6
Degree of sensitization distance6.16.110.4-2.23.02.73.2-2.62.01.72.71.72.82.71.9
Degree of sensitization stereotypy1.41.52.11.3-1.2-1.4-1.31.4-0.3-1.1-1.4-1.1-1.4-1.4-1.1
Condit. Reinf. active minus inactive responses0.20.21.20.3-1.1-0.5-0.60.30.30.2-0.50.1-0.5-0.50.1
Condit. Reinf. active-inactive response ratio0.30.30.60.7-0.4-0.5-0.80.7-0.6-0.5-0.5-0.6-0.6-0.6-0.3
Condit. Reinf. active responses0.40.51.4-0.4-1.20.0-0.1-0.41.21.00.11.00.10.10.7
Condit. Reinf. inactive responses1.92.24.8-1.6-0.80.90.9-1.62.22.01.02.11.01.11.6
Incentive salience index mean0.60.73.40.4-1.8-0.9-1.00.50.50.2-0.90.1-0.9-0.9-0.0
Condit. Reinf. lever presses0.50.74.30.0-2.1-0.8-0.90.20.60.7-0.80.6-0.7-0.70.2
Time in familiar zone, hab. session 10.30.20.4-0.40.50.50.6-0.60.30.50.50.40.60.50.2
Time in novel zone, hab. session 12.12.12.81.6-0.4-1.4-1.21.7-1.5-1.7-1.4-1.7-1.4-1.4-1.4
Total zone transitions, hab. session 10.20.31.60.2-1.3-0.5-0.70.20.70.3-0.50.2-0.5-0.5-0.3
Total locomotion distance, hab. session 10.40.61.6-0.8-1.00.3-0.0-0.71.31.20.31.10.30.30.6
Locomotion velocity, hab. session 11.01.53.5-1.4-1.30.50.0-1.11.91.90.51.80.60.61.1
Time in familiar zone, hab. session 20.30.31.30.21.20.30.10.1-1.0-0.50.2-0.60.30.1-0.3
Time in novel zone, hab. session 20.10.10.9-0.2-1.0-0.2-0.2-0.00.50.4-0.20.4-0.2-0.20.1
Total zone transitions, hab. session 20.71.03.90.6-2.0-1.0-1.50.7-0.10.0-1.0-0.1-1.0-1.1-0.5
Total locomotion distance, hab. session 20.10.21.2-0.1-1.1-0.2-0.60.00.20.5-0.20.4-0.2-0.30.0
Locomotion velocity, hab. session 20.30.42.30.1-1.5-0.5-1.00.20.10.4-0.50.2-0.5-0.6-0.2
Novel to familiar place preference ratio0.20.20.5-0.6-0.50.10.1-0.4-0.50.60.10.70.20.20.3
Novelty place preference0.20.30.7-0.7-0.50.20.2-0.5-0.50.70.30.90.30.30.5
Time in novel zone, NPP test0.20.20.6-0.7-0.60.2-0.0-0.4-0.70.60.20.80.20.20.4
Total zone transitions, NPP test0.70.92.2-1.1-0.80.70.1-1.01.31.50.71.40.60.71.0
Total locomotion distance, NPP test3.95.58.8-2.70.12.21.6-2.62.43.02.22.92.22.22.5
Locomotion velocity, NPP test3.24.67.5-2.40.22.01.6-2.42.32.72.02.62.02.02.2
Pavlov. Cond. lever latency0.20.31.4-0.11.20.70.5-0.3-0.6-0.30.6-0.20.60.5-0.0
Pavlov. Cond. magazine entry latency0.10.10.60.4-0.3-0.4-0.10.30.7-0.2-0.4-0.1-0.4-0.3-0.0
Pavlov. Cond. change in total contacts2.12.35.11.4-2.2-1.9-1.71.5-0.3-0.7-1.8-0.8-1.8-1.7-1.1
Pavlov. Cond. index score0.60.71.60.7-1.2-1.1-0.80.80.6-0.3-1.1-0.4-1.0-0.9-0.4
Pavlov. Cond. latency score0.40.51.40.5-1.2-0.9-0.60.60.7-0.1-0.9-0.2-0.9-0.8-0.2
Pavlov. Cond. lever contacts0.40.51.40.4-1.2-0.9-0.60.60.7-0.2-0.9-0.1-0.8-0.8-0.2
Pavlov. Cond. magazine entry number0.81.01.5-1.11.11.21.0-1.0-0.20.81.20.71.21.10.8
Pavlov. Cond. intertrial magazine entries0.50.61.5-0.9-0.80.50.2-0.80.71.20.41.20.40.40.9
Pavlov. Cond. lever-magazine prob. diff.0.81.01.81.0-1.4-1.3-1.01.00.5-0.6-1.3-0.6-1.2-1.1-0.6
Pavlov. Cond. response bias1.01.31.91.3-1.0-1.4-1.01.20.2-1.0-1.4-0.9-1.3-1.2-0.9
Bone: apparent density1.32.12.7-1.60.71.61.2-1.61.41.41.51.71.51.51.4
Bone surface0.61.02.1-1.1-0.10.90.6-1.20.91.30.81.50.90.91.1
Bone volume0.71.22.3-1.2-0.11.00.8-1.31.31.41.01.51.01.01.1
Bone: connectivity density3.14.85.9-2.41.62.42.0-2.41.42.12.42.22.42.42.4
Bone: cortical apparent density0.40.61.50.81.2-0.20.30.6-0.9-1.2-0.3-1.1-0.2-0.2-0.9
Bone: cortical area0.20.40.70.6-0.8-0.6-0.40.40.5-0.5-0.8-0.2-0.7-0.6-0.8
Bone: cortical porosity0.80.93.00.5-1.7-1.0-1.30.8-0.7-0.3-1.1-0.3-1.1-1.1-0.5
Bone: cortical porosity0.91.03.40.5-1.8-1.0-1.30.8-0.5-0.3-1.1-0.2-1.1-1.1-0.5
Bone: cortical thickness0.40.61.40.8-0.5-0.8-0.40.70.1-0.9-0.9-0.6-0.8-0.8-1.2
Bone: cortical thickness0.30.31.30.40.7-0.20.30.3-0.1-0.9-0.3-0.7-0.2-0.2-1.1
Bone: cortical tissue density0.50.71.60.91.3-0.30.30.7-0.9-1.3-0.3-1.2-0.3-0.3-1.0
Bone: elastic displacement0.50.61.6-0.6-1.20.3-0.3-0.61.01.30.21.10.10.20.9
Bone: elastic work0.70.94.4-0.5-2.1-0.2-0.8-0.41.11.2-0.31.3-0.3-0.20.7
Bone: endosteal estimation0.00.10.2-0.2-0.50.1-0.2-0.20.40.4-0.00.40.00.00.3
Bone: endosteal perimeter0.30.61.5-0.8-0.90.4-0.2-0.70.81.20.31.10.30.30.9
Bone: final force0.20.30.50.6-0.6-0.6-0.50.40.1-0.4-0.7-0.3-0.6-0.6-0.6
Bone: final moment0.20.31.00.5-1.0-0.7-0.60.40.2-0.2-0.8-0.0-0.7-0.7-0.5
Bone: marrow area0.10.10.3-0.3-0.40.2-0.1-0.30.50.50.10.50.10.10.4
Bone: maximum diameter0.50.91.31.0-0.8-0.9-0.90.9-0.2-0.9-1.1-0.8-1.1-1.0-1.2
Bone: maximum force0.50.81.60.9-1.3-1.0-1.00.8-0.1-0.6-1.2-0.4-1.0-1.1-1.0
Bone: maximum moment0.50.82.60.7-1.6-1.1-1.00.70.1-0.3-1.2-0.1-1.0-1.0-0.8
Bone: minimum diameter0.30.62.60.5-1.6-0.8-0.90.50.4-0.1-1.00.0-0.9-0.9-0.5
Bone: periosteal estimation0.10.10.50.1-0.7-0.2-0.30.10.60.1-0.40.2-0.3-0.3-0.2
Bone: periosteal perimeter0.10.20.5-0.3-0.70.2-0.2-0.40.70.70.10.70.10.10.3
Bone: post-yield work0.60.82.71.01.1-0.40.50.60.1-1.4-0.4-1.2-0.3-0.3-1.6
Bone: stiffness0.40.71.10.9-0.4-0.9-0.70.9-0.6-1.0-0.9-0.9-0.8-0.9-1.0
Bone: tissue strength0.10.10.3-0.3-0.50.1-0.0-0.30.10.50.10.60.10.10.3
Bone: trabecular number2.13.24.2-2.01.01.91.7-2.01.61.71.91.91.91.91.8
Bone: trabecular spacing1.82.32.81.6-1.1-1.6-1.61.7-1.0-1.3-1.6-1.5-1.6-1.7-1.5
Bone: trabecular thickness0.30.31.1-0.6-0.10.40.4-0.61.10.50.30.80.40.40.4
Bone: trabecular tissue density1.11.52.31.1-1.0-1.2-1.11.3-1.5-1.2-1.3-1.1-1.2-1.3-1.2
Breakpoint value in progressive ratio session0.40.40.7-0.90.30.80.3-0.7-0.20.60.80.70.80.60.5
Distance traveled before self-admin0.80.91.60.9-1.3-1.1-1.00.9-0.6-0.6-1.1-0.6-1.1-1.1-0.8
Distance traveled after self-admin0.91.01.51.2-0.9-1.0-1.11.1-0.1-0.8-1.0-1.1-1.1-1.1-1.1
Delta time in closed arm before/after self-admin0.30.31.2-0.40.30.40.6-0.51.10.50.50.40.40.50.6
Delta time in open arm before/after self-admin0.40.40.9-0.51.00.80.6-0.6-0.30.30.70.30.70.70.5
Diff in mean of infusions in LGA sessions0.50.61.80.4-1.2-0.7-1.20.7-1.4-0.1-0.7-0.3-0.7-0.8-0.0
Extinction: sum of active levers before priming2.42.44.5-1.51.21.51.6-1.62.11.51.51.41.51.51.4
Active lever presses in extinction session 60.30.31.0-0.51.00.60.8-0.40.40.30.60.10.60.60.3
Delta distance traveled before/after self-admin0.60.61.31.00.1-0.6-0.81.0-0.8-0.8-0.6-1.1-0.7-0.7-0.7
Delta ambulatory time before/after self-admin0.50.61.00.9-0.2-0.6-0.90.9-0.8-0.7-0.7-1.0-0.7-0.7-0.7
Time in closed arm before self-admin0.60.72.10.8-0.5-0.6-1.10.9-1.5-0.6-0.6-0.7-0.7-0.7-0.6
Time in closed arm after self-admin0.10.10.20.2-0.5-0.2-0.40.1-0.10.4-0.10.1-0.2-0.20.3
Time in open arm before self-admin0.10.10.2-0.3-0.40.10.1-0.30.20.30.10.40.20.00.0
Time in open arm after self-admin0.40.50.9-0.60.90.80.8-0.70.50.30.80.40.90.80.5
Sum of active levers in priming session hrs 5-60.90.92.7-0.71.71.21.2-0.80.10.41.00.21.21.00.6
Time to tail flick, vehicle, before self-admin0.10.10.3-0.5-0.20.20.3-0.2-0.20.20.00.40.20.10.3
Time to tail flick, vehicle, after self-admin1.81.910.11.0-0.2-0.8-1.51.3-3.2-1.3-0.8-1.3-0.9-1.0-1.2
Time to tail flick, test, before self-admin0.80.84.6-0.6-0.10.70.6-0.72.10.80.60.80.60.70.6
Time to tail flick, test, after self-admin6.36.58.9-2.33.03.02.7-2.52.01.92.91.82.92.82.3
Delta time to tail flick, vehicle, before/after SA0.70.62.70.80.7-0.3-0.50.7-1.6-1.0-0.2-1.0-0.3-0.3-0.8
Delta time to tail flick, test, before/after SA1.91.76.8-1.02.61.51.5-1.1-0.30.51.50.31.51.40.9
Ambulatory time before self-admin0.50.51.00.7-1.0-0.9-0.50.70.3-0.5-0.9-0.5-0.8-0.9-0.7
Ambulatory time after self-admin1.51.72.41.5-1.3-1.4-1.41.5-0.1-1.1-1.4-1.3-1.4-1.4-1.3
Total heroin consumption2.32.76.61.2-1.4-1.7-1.61.6-2.6-1.3-1.8-1.3-1.6-1.7-1.5
Area under the delay curve0.20.20.40.7-0.6-0.5-0.40.50.4-0.4-0.5-0.3-0.5-0.5-0.7
Delay disc. indifference point, 0s delay1.31.43.1-1.2-0.60.80.4-1.21.61.80.91.60.80.91.4
Delay disc. indifference point, 16s delay0.10.20.40.70.1-0.1-0.10.40.3-0.6-0.3-0.5-0.2-0.2-0.6
Delay disc. indifference point, 2s delay0.40.42.5-0.2-1.6-0.5-0.7-0.10.10.8-0.30.6-0.4-0.30.3
Delay disc. indifference point, 24s delay0.40.30.90.9-0.2-0.5-0.40.70.0-0.6-0.5-0.8-0.5-0.5-0.8
Delay disc. indifference point, 4s delay1.21.21.81.4-0.9-1.1-1.11.3-0.8-1.0-1.2-1.1-1.1-1.2-1.1
Delay disc. indifference point, 8s delay0.50.51.20.8-0.3-0.7-0.30.70.0-1.1-0.7-0.6-0.7-0.6-1.1
Delay discount exponential model param0.60.71.2-1.10.80.80.7-0.9-0.10.80.90.70.90.81.1
Delay discount hyperbolic model param0.80.91.3-1.11.11.00.9-1.00.10.81.00.71.01.01.1
Fecal boli incidents, locomotor time 12.32.54.31.6-1.0-1.6-1.21.7-1.7-2.1-1.6-1.5-1.5-1.5-1.9
Change in fecal boli incidents, locomotor task0.30.30.7-0.20.80.50.4-0.4-0.30.70.40.20.60.30.8
Time >=10cm from walls, locomotor time 10.60.61.4-1.1-0.00.60.6-1.00.80.90.51.20.60.61.0
Bouts of movement, locomotor time 10.90.91.80.8-0.4-0.8-1.11.0-1.4-1.2-0.7-1.1-0.8-0.8-1.1
Total resting periods, locomotor time 11.11.22.31.10.2-0.8-1.01.2-1.5-1.5-0.7-1.5-0.8-0.9-1.4
Rest time, locomotor task time 11.41.52.81.40.3-0.9-1.01.2-1.7-1.5-0.9-1.6-0.9-1.0-1.6
Distance moved, locomotor task time 11.21.32.1-1.40.11.10.9-1.21.01.31.01.41.01.01.4
Vertical activity count, locomotor time 10.50.63.3-0.5-1.8-0.5-0.6-0.10.21.0-0.40.8-0.5-0.30.5
Time >=10cm from walls, locomotor time 20.20.20.50.4-0.5-0.5-0.60.4-0.7-0.1-0.5-0.2-0.5-0.5-0.1
Bouts of movement, locomotor time 21.21.34.11.30.2-1.0-1.11.2-2.0-1.1-0.7-1.4-1.0-0.8-1.3
Total resting periods, locomotor time 22.22.34.31.80.3-1.3-1.21.6-2.1-1.7-1.1-2.0-1.3-1.2-1.8
Rest time, locomotor task time 25.15.911.93.00.5-2.2-1.32.6-1.0-3.5-2.1-3.2-2.2-2.0-3.4
Distance moved, locomotor task time 22.12.45.4-1.9-0.61.20.7-1.71.32.31.02.21.21.12.1
Vertical activity count, locomotor time 20.80.93.7-0.8-1.9-0.2-0.5-0.50.51.7-0.21.4-0.2-0.21.0
Weight adjusted by age1.51.73.70.6-1.9-1.3-1.91.1-1.7-0.6-1.3-0.4-1.4-1.3-0.5
Seeking ratio, delayed vs. immediate footshock0.91.02.4-1.0-0.50.60.6-1.11.11.60.61.40.80.61.4
Locomotion in novel chamber0.10.10.40.3-0.0-0.40.40.10.6-0.5-0.4-0.2-0.3-0.3-0.7
Locomotion in novel chamber post-restriction0.70.91.51.1-0.5-0.9-0.81.00.3-1.0-0.9-1.0-1.0-0.9-1.2
Progressive ratio0.60.71.00.9-1.0-0.8-0.90.90.5-0.5-1.0-0.7-0.9-1.0-0.5
Food seeking constrained by brief footshock0.50.62.50.81.6-0.10.10.6-0.7-1.00.1-1.4-0.0-0.1-0.6
Seeking ratio, punishment vs. effort0.20.31.60.11.30.20.40.0-0.8-0.50.4-0.50.30.4-0.3
Run reversals in cocaine runway, females1.61.66.7-1.00.91.11.4-1.22.60.81.20.91.01.30.7
Run reversals in cocaine runway, males7.26.98.52.9-2.0-2.9-2.52.9-1.2-2.6-2.9-2.6-2.9-2.8-2.8
Latency to leave start box in cocaine runway1.21.32.41.5-0.7-1.3-1.31.2-0.5-0.9-1.2-1.2-1.3-1.3-1.0
Latency to leave start box in cocaine runway, F2.73.04.02.0-1.2-1.9-1.91.9-1.4-1.3-1.9-1.7-1.9-1.9-1.4
Latency to leave start box in cocaine runway, M0.70.71.2-0.80.50.80.7-1.01.10.70.91.00.80.90.8
Cd content in liver0.10.10.2-0.40.00.30.4-0.40.20.40.30.40.30.30.4
Co content in liver1.72.03.11.7-0.1-1.1-1.21.5-1.8-1.6-1.1-1.8-1.2-1.2-1.7
Cu content in liver0.81.01.51.2-0.3-0.9-0.91.1-1.1-1.1-0.9-1.2-0.9-0.9-1.0
Fe content in liver0.91.11.9-0.91.01.11.1-1.01.40.71.10.81.11.11.1
K content in liver0.90.91.3-0.71.01.01.0-1.01.10.81.00.71.01.00.8
Mg content in liver0.70.71.4-0.60.80.90.9-0.91.20.70.90.60.90.90.7
Mn content in liver3.03.45.1-1.81.01.91.8-2.02.32.01.91.91.81.91.8
Na content in liver2.42.59.80.9-3.1-1.8-2.11.2-0.2-0.1-1.8-0.1-1.8-1.8-0.5
Rb content in liver0.30.31.4-0.11.20.50.9-0.30.6-0.20.5-0.10.50.50.2
Se content in liver2.02.45.3-1.7-1.21.10.4-1.51.72.31.12.21.01.02.1
Sr content in liver1.11.01.7-1.10.41.10.7-1.1-0.11.21.11.11.01.11.3
Zn content in liver1.01.14.00.7-2.0-1.2-1.40.8-0.8-0.1-1.2-0.2-1.2-1.2-0.3