Hub : Genes

Nptxr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016156 0.35 0.1 0.0e+00 0.33 0.34 0.35 0.35 2.6e-37 5.1e-39 1.5e-40 5.9e-40
2 Adipose mRNA stability ENSRNOG00000016156 0.06 0.03 9.3e-07 0.03 0.03 0.04 0.03 3.1e-04 1.2e-04 1.5e-05 5.0e-04
3 Brain gene expression ENSRNOG00000016156 0.14 0.06 2.8e-11 0.07 0.13 0.13 0.1 5.5e-07 6.6e-12 5.6e-12 6.0e-10
4 Brain mRNA stability ENSRNOG00000016156 0.06 0.03 9.2e-05 0.05 0.03 0.04 0.03 1.9e-05 1.1e-03 1.3e-04 3.7e-04
5 IL gene expression ENSRNOG00000016156 0.37 0.14 2.4e-03 0.2 0.1 0.1 0.16 1.6e-05 2.1e-03 2.4e-03 1.3e-04
6 LHb mRNA stability ENSRNOG00000016156 0.14 0.09 8.0e-03 0.04 0.07 0.02 -0 3.4e-02 1.1e-02 1.2e-01 3.5e-01
7 Liver gene expression ENSRNOG00000016156 0.11 0.06 1.5e-09 0.06 0.08 0.08 0.08 1.3e-07 5.7e-09 5.5e-09 5.2e-09
8 OFC mRNA stability ENSRNOG00000016156 0.32 0.13 2.7e-05 0.17 0.13 0.1 0.04 6.4e-05 6.5e-04 2.3e-03 3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.20.51.9-0.6-0.2-0.40.31.20.2-1.40.3
BMI without tail0.20.31.2-0.00.6-0.3-1.11.0-0.1-0.0-0.2
Body weight1.45.910.3-2.7-3.0-1.23.20.11.4-3.12.7
Epididymis fat weight2.55.812.8-2.2-2.6-1.82.70.22.2-3.62.7
Glucose0.30.50.9-0.9-1.00.00.8-0.8-0.0-0.50.9
Heart weight2.23.25.6-2.4-2.2-1.02.3-1.50.9-1.71.7
Left kidney weight4.613.228.2-3.3-4.4-1.15.30.22.1-5.33.7
Right kidney weight5.415.438.9-3.6-4.8-0.56.2-1.01.6-5.53.8
Tail length0.51.42.3-1.5-1.4-0.90.8-1.50.8-0.41.5
Length with tail1.97.113.9-2.9-3.6-1.43.7-1.31.7-2.43.1
Length without tail2.55.515.5-2.2-3.0-0.83.9-1.01.4-2.52.2
Liver weight, left1.11.82.5-1.2-1.3-1.11.31.51.4-1.61.2
Liver weight, right4.57.511.9-2.8-3.0-2.81.9-0.13.1-3.13.4
Parametrial fat weight0.61.22.9-1.2-0.9-1.20.2-1.71.0-0.71.1
Retroperitoneal fat weight3.612.026.3-3.7-3.9-2.13.9-0.32.8-5.13.7
Intraocular pressure0.30.51.8-0.3-0.60.10.80.60.2-1.30.7
Extensor digitorum longus weight0.51.94.31.02.00.2-2.10.9-0.71.5-1.6
Soleus weight0.72.04.71.31.11.5-0.4-2.2-1.31.3-1.5
Tibialis anterior weight2.06.811.82.63.41.7-3.20.3-2.22.7-3.3
Tibia length0.20.51.3-0.0-0.70.61.11.0-0.4-0.70.5
Number of licking bursts0.70.81.71.11.10.1-1.20.1-0.41.3-0.9
Food consumed during 24 hour testing period0.40.41.1-0.1-0.20.80.41.0-0.9-0.90.1
Times rat made contact with spout0.40.41.70.40.40.1-0.6-1.3-0.30.8-0.3
Mean time between licks in bursts0.91.22.60.91.40.3-1.11.6-0.51.0-1.4
Mean num. licks in bursts0.60.71.1-1.0-1.0-0.40.8-1.10.6-0.90.9
Std. dev. time between licks in bursts0.40.50.90.60.60.80.2-0.1-0.80.9-1.0
Water consumed over 24 hours0.10.10.50.20.10.3-0.0-0.5-0.40.7-0.3
Indifference point 0 sec0.30.51.6-0.5-0.30.31.2-1.3-0.20.4-0.2
Indifference point AUC2.32.84.52.11.81.6-0.8-0.0-1.62.0-2.0
Indifference point function ln k3.14.46.8-2.6-2.3-1.81.60.32.0-2.62.5
Indifference point function log k3.14.46.8-2.6-2.3-1.81.60.32.0-2.62.5
Delay discounting total patch changes 0 sec0.20.41.4-0.20.10.40.8-1.2-0.40.8-0.5
Delay discounting total patch changes 12 sec0.71.02.30.90.71.50.90.1-1.30.6-1.2
Delay discounting total patch changes 18 sec1.41.94.61.21.02.00.4-0.4-2.11.1-1.5
Delay discounting total patch changes 24 sec0.81.01.51.01.11.0-0.3-1.2-1.01.1-1.2
Delay discounting total patch changes 6 sec1.21.93.21.31.21.70.3-0.4-1.81.6-1.7
Delay discounting time to switch 0 sec0.40.62.30.20.20.80.11.5-0.6-1.1-0.3
Delay discounting water rate 0 sec0.71.05.3-0.7-0.8-0.40.9-2.30.40.90.3
Delay discounting water rate 12 sec0.40.51.3-1.1-0.5-1.10.2-0.60.90.00.5
Delay discounting water rate 18 sec0.20.31.0-0.6-0.5-0.40.3-1.00.20.70.2
Delay discounting water rate 24 sec2.12.95.4-2.3-2.2-1.41.8-0.91.3-1.22.0
Delay discounting water rate 6 sec0.81.12.7-0.9-0.8-1.4-0.1-1.61.30.50.9
Locomotor activity1.01.53.2-1.5-1.4-0.71.50.30.6-1.81.2
Locomotor testing distance0.10.10.6-0.5-0.1-0.8-0.2-0.30.4-0.10.2
Locomotor testing rearing0.40.72.3-0.7-0.8-0.20.90.50.4-1.50.7
Light reinforcement 10.10.10.4-0.00.30.20.10.7-0.30.1-0.4
Light reinforcement 20.81.11.9-1.1-0.7-1.00.41.21.1-1.41.1
Reaction time number correct0.60.93.00.10.5-1.4-1.70.41.20.40.4
Reaction time mean minus median0.00.10.2-0.3-0.3-0.10.2-0.10.0-0.30.4
Reaction time mean minus median AUC0.50.61.1-0.8-0.9-0.40.7-0.50.6-1.11.0
Reaction time num false alarms0.10.20.8-0.6-0.1-0.30.9-0.10.3-0.20.0
Reaction time num false alarms AUC0.10.10.5-0.40.1-0.40.7-0.20.3-0.0-0.2
Reaction time trials correct on left0.60.93.00.10.5-1.4-1.70.41.20.40.4
Reaction time trials on left0.70.93.30.20.6-1.4-1.80.51.10.50.4
Reaction time mean0.20.30.7-0.6-0.8-0.10.6-0.50.2-0.40.8
Reaction time mean AUC0.20.20.6-0.5-0.7-0.20.4-0.40.2-0.30.7
Median of all reaction times0.10.10.3-0.4-0.60.10.4-0.30.0-0.10.5
Reaction time omissions1.41.94.51.61.50.7-1.62.1-1.01.0-1.0
Reaction time false alarm rate0.20.31.6-0.5-0.20.21.3-0.5-0.0-0.3-0.2
Reaction time premature initiation rate0.40.51.6-0.0-0.31.20.90.4-1.2-0.3-0.1
Reaction time premature initiations0.10.10.3-0.1-0.20.40.20.4-0.5-0.20.3
Std. dev. reaction times0.50.71.5-1.0-1.2-0.31.0-0.50.3-0.91.2
Reaction time trials completed0.70.93.30.20.6-1.4-1.80.51.10.50.4
Reaction time trials AUC0.50.82.3-0.00.3-1.4-1.50.51.10.20.5
Social response proportion0.90.95.50.00.50.60.22.3-0.9-0.1-0.7
Social responses1.11.42.91.01.51.0-0.51.3-1.20.8-1.7
Social time3.14.16.52.22.32.0-1.60.8-2.22.0-2.6
Conditioned locomotion0.30.41.3-0.6-0.7-0.21.10.30.5-0.70.5
Cocaine response after cond. corrected0.50.62.20.40.10.90.51.5-0.8-0.2-0.6
Cocaine response after cond. not corrected0.30.42.00.20.00.60.41.4-0.6-0.3-0.3
Cocaine response before conditioning0.20.20.6-0.20.1-0.7-0.8-0.30.6-0.00.4
Saline control response0.81.12.2-1.2-0.8-1.40.9-1.01.5-0.70.7
Condit. Reinf. active minus inactive responses1.01.22.41.40.91.6-0.2-0.0-1.50.8-1.3
Condit. Reinf. active-inactive response ratio0.60.61.80.80.31.40.50.0-1.30.3-0.8
Condit. Reinf. active responses0.50.71.81.00.61.4-0.00.5-1.20.1-0.9
Condit. Reinf. inactive responses0.20.30.70.70.50.5-0.60.8-0.4-0.3-0.3
Condit. Reinf. lever presses0.40.60.80.80.70.7-0.8-0.9-0.70.9-0.5
Condit. Reinf. lever reinforcers received0.50.72.00.90.41.40.20.3-1.20.1-0.8
Pavlov. Cond. lever latency0.10.20.80.40.2-0.2-0.30.90.3-0.4-0.0
Pavlov. Cond. magazine entry latency1.72.03.41.21.41.4-0.6-0.9-1.71.7-1.8
Pavlov. Cond. change in total contacts0.81.12.9-0.1-0.51.71.6-0.4-1.60.1-0.5
Pavlov. Cond. index score0.60.81.50.50.61.0-0.0-1.2-1.01.1-1.1
Pavlov. Cond. latency score0.91.12.10.70.71.2-0.1-1.4-1.21.3-1.2
Pavlov. Cond. lever contacts0.10.21.3-0.4-0.20.10.2-1.1-0.10.3-0.0
Pavlov. Cond. magazine entry number0.50.71.9-0.4-0.5-0.80.11.40.8-0.90.9
Pavlov. Cond. intertrial magazine entries0.20.20.40.4-0.50.50.2-0.6-0.3-0.60.6
Pavlov. Cond. lever-magazine prob. diff.0.50.71.20.40.50.8-0.1-1.1-0.91.0-1.0
Pavlov. Cond. response bias0.30.40.90.30.40.9-0.0-0.6-0.90.6-0.7
Conditioned reinforcement - actives1.71.73.11.81.51.3-0.90.6-1.31.1-1.6
Conditioned reinforcement - inactives1.71.93.21.41.31.4-0.9-0.8-1.81.7-1.4
Conditioned locomotion1.31.63.41.41.01.80.30.9-1.70.2-1.6
Intermittent access intake day 1-15 change0.20.21.00.50.4-0.0-0.3-0.5-0.11.0-0.3
Intermittent access intake escalation0.20.20.90.50.5-0.0-0.5-0.3-0.20.9-0.2
Intermittent access intake escalation 20.10.10.50.20.3-0.0-0.1-0.7-0.20.6-0.3
Intermitt. access day 1 inactive lever presses0.40.41.30.2-0.31.20.8-0.4-1.00.2-0.2
Intermitt. access day 15 inactive lever presses0.40.41.00.80.01.00.6-0.4-1.00.5-0.2
Intermitt. access escalation Index0.30.31.20.40.6-0.1-1.10.4-0.30.6-0.1
Intermittent access day 1 total infusions1.01.22.70.90.61.60.51.3-1.6-0.0-0.9
Intermittent access day 15 total infusions1.11.22.61.20.81.50.20.6-1.61.0-1.1
Intermittent access terminal intake (last 3 days)0.60.71.31.00.71.00.10.5-1.10.8-0.8
Intermittent access total infusions1.61.83.91.41.11.90.11.3-2.00.5-1.3
Intermittent access day 1 locomotion0.70.72.00.60.31.40.60.4-1.40.1-0.6
Intermittent access day 15 total locomotion0.20.20.50.3-0.00.60.5-0.2-0.7-0.2-0.0
Intermittent access total locomotion0.60.71.70.3-0.31.31.3-0.3-1.3-0.4-0.1
Intermittent access standard deviation0.91.03.10.70.11.81.30.4-1.50.0-0.7
Cocaine induced anxiety0.80.92.2-1.1-1.1-0.80.50.20.8-1.51.1
Post-drug Anxiety2.02.24.1-1.8-2.0-1.11.4-0.91.2-1.31.7
Baseline Anxiety0.50.53.0-0.2-0.3-0.50.0-1.70.30.90.2
Lifetime Intake1.92.15.01.41.02.20.31.4-2.20.2-1.4
Incentive Sensitization - Responses0.20.20.70.10.2-0.2-0.7-0.80.2-0.00.2
Incentive Sensitization - Breakpoint0.20.20.70.10.1-0.2-0.7-0.80.2-0.20.2
Progressive ratio test 1 active lever presses1.71.73.71.61.11.9-0.30.6-1.90.8-1.2
Progressive ratio test 1 breakpoint1.01.02.11.30.91.4-0.30.3-1.50.8-1.0
Progressive ratio test 1 inactive lever presses1.61.73.41.31.51.7-0.80.6-1.80.5-1.5
Progressive ratio test 2 active lever presses0.91.01.91.41.01.3-0.7-0.3-1.30.6-0.8
Progressive ratio test 2 breakpoint1.01.12.31.41.01.5-0.5-0.1-1.50.5-1.0
Progressive ratio test 2 inactive lever presses2.02.33.71.91.71.6-1.30.0-1.81.4-1.5
Total sessions with >9 infusions0.60.61.90.60.11.40.80.3-1.2-0.7-0.5
Short access day 1 total inactive lever presses1.61.84.81.10.52.21.00.2-2.10.9-1.4
Short access day 10 total inactive lever presses1.31.43.2-1.2-1.5-0.21.8-1.70.4-0.41.2
Short access day 1 total infusions0.50.51.60.50.01.30.80.1-1.0-0.4-0.5
Short access day 10 total infusions1.41.53.80.80.52.00.91.5-1.8-0.6-1.0
Short access total infusions1.41.54.30.80.32.11.11.2-1.8-0.8-0.9
Short access day 1 locomotion0.90.92.50.80.61.60.20.4-1.40.3-1.1
Short access day 10 total locomotion0.80.82.60.40.41.60.3-0.9-1.50.3-0.7
Short access total locomotion1.11.23.90.40.22.01.1-0.3-1.7-0.4-1.0
Compulsive drug intake1.11.12.80.70.8-0.4-1.5-1.50.01.7-0.5
One hour access (0.3 mA shock)3.33.86.02.42.51.7-1.81.1-1.91.8-2.2
One hour access (shock baseline)0.60.71.50.80.91.0-0.21.2-1.00.0-0.9
Number of responses in last shaping day5.15.17.52.32.52.6-1.62.1-2.71.0-2.7
Context. condit. distance diff. score6.17.49.7-2.9-3.0-2.52.4-1.43.0-2.93.1
Locomotion velocity, session 10.90.91.81.10.61.20.70.7-1.10.6-1.4
Locomotion distance, session 15.16.611.63.42.81.8-2.41.6-2.03.0-2.9
Locomotion velocity, session 20.60.74.20.70.40.50.22.1-0.5-0.3-0.5
Locomotion distance, session 25.88.213.03.63.02.8-2.11.5-3.12.9-3.4
Locomotion velocity, session 31.92.25.4-1.4-1.4-2.10.9-0.42.3-1.01.5
Locomotion distance, session 30.80.92.00.50.6-1.4-1.4-0.51.11.10.1
Stereotopy head waving bouts, day 30.40.51.5-0.5-0.80.61.20.2-0.4-0.90.4
Stereotopy head waving duration, day 32.02.46.1-1.7-1.90.02.50.60.3-2.11.4
Locomotion velocity, session 70.40.41.4-0.4-0.7-0.40.6-0.00.8-1.20.6
Locomotion distance, session 70.30.41.50.60.00.90.5-1.2-0.50.2-0.4
Stereotopy head waving bouts, day 73.84.47.2-2.3-2.1-1.82.11.12.0-2.72.2
Stereotopy head waving duration, day 73.74.67.1-2.5-1.9-2.31.51.12.4-2.72.3
Locomotion velocity, session 81.01.13.6-0.6-1.3-0.01.90.60.3-1.50.9
Locomotion distance, session 80.30.51.2-0.5-0.7-0.70.6-0.11.1-0.60.7
Degree of sensitization distance1.81.95.6-0.9-1.31.42.4-1.1-0.7-1.70.4
Degree of sensitization stereotypy3.03.34.8-1.8-1.5-2.01.41.42.2-2.21.8
Condit. Reinf. active minus inactive responses0.20.31.70.20.20.0-0.1-1.30.00.4-0.4
Condit. Reinf. active-inactive response ratio0.50.51.7-0.6-0.5-0.80.4-1.30.9-0.30.4
Condit. Reinf. active responses0.70.95.20.00.4-0.4-0.6-2.30.40.9-0.4
Condit. Reinf. inactive responses0.91.15.5-0.10.3-0.6-0.9-2.40.41.2-0.2
Incentive salience index mean0.30.42.20.30.40.0-0.3-1.5-0.00.8-0.5
Condit. Reinf. lever presses0.20.31.60.30.30.1-0.4-1.3-0.10.7-0.3
Time in familiar zone, hab. session 10.40.40.90.90.50.7-0.20.9-0.70.5-0.4
Time in novel zone, hab. session 11.31.22.4-1.6-1.3-0.91.3-0.00.8-1.21.1
Total zone transitions, hab. session 11.52.25.51.51.7-0.7-2.0-0.00.42.4-1.4
Total locomotion distance, hab. session 10.50.71.60.40.5-1.3-0.8-0.31.01.3-0.1
Locomotion velocity, hab. session 10.60.82.90.90.7-0.8-1.1-0.40.51.7-0.4
Time in familiar zone, hab. session 20.50.61.7-0.3-0.2-1.3-0.70.11.10.20.8
Time in novel zone, hab. session 20.50.51.50.30.21.20.6-0.4-1.2-0.2-0.7
Total zone transitions, hab. session 22.02.64.52.11.61.5-1.10.2-1.62.1-1.9
Total locomotion distance, hab. session 21.62.13.11.81.41.6-0.50.7-1.71.6-1.8
Locomotion velocity, hab. session 21.92.63.91.91.51.7-0.70.5-1.82.0-2.0
Novel to familiar place preference ratio2.12.23.4-1.7-1.7-1.61.3-0.31.4-1.31.8
Novelty place preference3.03.14.8-2.0-1.9-2.01.5-0.31.8-1.62.2
Time in novel zone, NPP test3.53.65.8-2.1-2.1-2.21.6-0.52.0-1.72.4
Total zone transitions, NPP test2.43.48.32.32.20.3-2.00.1-0.62.9-2.1
Total locomotion distance, NPP test1.11.53.61.71.30.8-0.80.1-0.71.9-1.5
Locomotion velocity, NPP test1.52.24.32.01.70.8-1.20.3-0.82.1-1.9
Pavlov. Cond. lever latency0.10.10.3-0.4-0.4-0.10.50.10.1-0.50.3
Pavlov. Cond. magazine entry latency1.72.33.31.81.61.5-1.01.3-1.61.4-1.5
Pavlov. Cond. change in total contacts2.93.04.52.11.91.9-1.10.9-2.01.5-2.1
Pavlov. Cond. index score0.60.81.51.10.81.2-0.30.6-1.10.7-1.0
Pavlov. Cond. latency score0.30.40.80.80.60.9-0.20.4-0.80.5-0.7
Pavlov. Cond. lever contacts0.40.50.80.90.70.8-0.60.0-0.70.8-0.8
Pavlov. Cond. magazine entry number1.11.42.5-1.6-1.3-1.20.8-0.91.2-1.11.2
Pavlov. Cond. intertrial magazine entries0.50.73.70.20.10.1-0.3-1.9-0.31.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.70.81.41.20.91.1-0.50.6-1.00.8-1.0
Pavlov. Cond. response bias1.21.52.51.61.21.5-0.70.6-1.41.0-1.2
Bone: apparent density0.00.00.1-0.0-0.1-0.1-0.1-0.2-0.10.30.2
Bone surface0.10.20.90.50.20.4-0.11.0-0.50.4-0.3
Bone volume0.00.00.10.1-0.0-0.1-0.10.20.00.10.2
Bone: connectivity density0.10.10.3-0.2-0.5-0.00.5-0.5-0.00.00.4
Bone: cortical apparent density0.60.82.3-0.40.1-1.5-0.7-1.01.40.40.1
Bone: cortical area0.30.41.20.10.20.70.71.1-0.6-0.9-0.4
Bone: cortical porosity0.91.02.6-0.7-0.60.81.31.2-0.5-1.60.5
Bone: cortical porosity1.41.53.7-0.6-0.61.11.61.7-0.9-1.90.3
Bone: cortical thickness0.71.12.41.11.50.9-0.90.4-1.00.3-1.6
Bone: cortical thickness1.92.23.41.81.81.4-1.30.5-1.61.2-1.8
Bone: cortical tissue density0.60.82.3-0.50.0-1.5-0.6-1.01.40.40.2
Bone: elastic displacement0.20.30.9-0.6-0.6-0.20.90.20.4-0.20.4
Bone: elastic work0.91.24.2-0.6-0.80.92.01.2-0.6-1.20.1
Bone: endosteal estimation0.81.74.3-1.0-1.60.52.11.3-0.2-1.61.3
Bone: endosteal perimeter1.22.45.2-1.0-1.50.02.02.00.3-2.31.5
Bone: final force0.60.92.30.40.01.50.71.5-1.3-0.7-0.4
Bone: final moment0.60.92.20.2-0.11.50.91.4-1.4-0.7-0.5
Bone: marrow area0.91.84.7-1.0-1.60.52.21.3-0.2-1.61.3
Bone: maximum diameter1.32.45.9-1.0-1.40.52.41.7-0.2-2.31.0
Bone: maximum force0.71.32.90.4-0.01.71.01.6-1.6-0.9-0.5
Bone: maximum moment0.81.43.00.2-0.11.71.21.6-1.6-1.0-0.6
Bone: minimum diameter0.30.51.5-0.1-0.30.81.00.7-0.6-1.20.1
Bone: periosteal estimation0.71.33.0-0.6-0.90.71.71.6-0.5-1.60.6
Bone: periosteal perimeter1.42.46.0-1.1-1.40.42.31.80.0-2.41.2
Bone: post-yield work1.21.63.51.40.81.5-0.51.5-1.90.8-1.0
Bone: stiffness0.50.81.5-0.2-0.51.21.21.0-1.2-1.10.0
Bone: tissue strength0.20.20.6-0.5-0.5-0.20.80.10.2-0.60.4
Bone: trabecular number0.40.61.2-0.6-0.8-1.00.2-0.21.1-0.51.1
Bone: trabecular spacing0.81.02.70.90.41.60.41.0-1.6-0.2-0.7
Bone: trabecular thickness0.70.81.6-0.8-0.7-1.0-0.0-1.31.2-0.51.0
Bone: trabecular tissue density0.30.41.4-0.70.2-0.4-0.4-1.20.20.9-0.4
Breakpoint value in progressive ratio session0.20.31.00.40.50.4-1.00.1-0.70.2-0.2
Distance traveled before self-admin2.22.33.71.71.81.8-0.81.0-1.61.0-1.9
Distance traveled after self-admin1.01.13.80.80.21.90.6-0.2-1.80.5-0.7
Delta time in closed arm before/after self-admin0.30.20.50.50.50.60.50.2-0.4-0.5-0.7
Delta time in open arm before/after self-admin0.10.10.20.20.30.2-0.40.1-0.30.4-0.3
Diff in mean of infusions in LGA sessions0.30.40.60.80.40.6-0.7-0.4-0.70.6-0.4
Extinction: sum of active levers before priming2.22.24.31.91.71.0-2.11.5-1.21.0-0.9
Active lever presses in extinction session 60.20.20.30.60.30.6-0.10.4-0.5-0.20.2
Delta distance traveled before/after self-admin1.61.74.0-1.2-2.0-0.31.8-1.30.4-0.91.7
Delta ambulatory time before/after self-admin1.01.12.9-0.8-1.60.21.7-0.9-0.1-0.61.1
Time in closed arm before self-admin1.11.32.50.61.11.1-0.8-0.2-1.51.5-1.6
Time in closed arm after self-admin0.40.41.4-0.6-0.40.41.2-1.0-0.3-0.6-0.2
Time in open arm before self-admin0.60.61.5-0.6-0.9-1.00.2-0.71.2-0.20.9
Time in open arm after self-admin0.30.41.0-0.4-0.1-1.0-0.8-0.41.00.20.4
Sum of active levers in priming session hrs 5-60.20.20.30.50.10.5-0.50.3-0.50.50.3
Time to tail flick, vehicle, before self-admin0.10.10.5-0.0-0.6-0.20.4-0.1-0.10.10.7
Time to tail flick, vehicle, after self-admin0.30.40.6-0.7-0.4-0.80.2-0.80.70.30.7
Time to tail flick, test, before self-admin0.80.81.80.91.30.2-1.30.3-0.30.3-1.3
Time to tail flick, test, after self-admin0.50.51.40.20.8-0.5-1.2-0.40.11.1-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.00.70.5-0.10.0-0.20.4-0.7
Delta time to tail flick, test, before/after SA0.70.61.5-0.5-0.0-1.2-0.6-0.80.71.10.7
Ambulatory time before self-admin1.61.62.81.41.61.2-1.20.1-1.11.3-1.7
Ambulatory time after self-admin0.80.92.10.90.51.40.3-0.4-1.41.1-0.9
Total heroin consumption0.81.01.51.21.20.7-1.01.2-0.90.6-1.1
Area under the delay curve4.14.46.12.52.41.7-2.30.9-1.82.3-2.3
Delay disc. indifference point, 0s delay0.30.30.7-0.20.20.90.20.7-0.8-0.5-0.3
Delay disc. indifference point, 16s delay5.35.37.42.72.71.7-2.41.4-2.02.6-2.6
Delay disc. indifference point, 2s delay5.25.88.92.83.01.9-2.62.4-2.11.3-2.6
Delay disc. indifference point, 24s delay1.11.13.21.30.80.7-0.60.8-0.91.8-0.9
Delay disc. indifference point, 4s delay2.82.94.02.02.01.7-1.41.1-1.71.6-2.0
Delay disc. indifference point, 8s delay3.13.26.32.01.91.3-2.1-0.5-1.42.5-1.9
Delay discount exponential model param4.24.46.3-2.5-2.5-1.62.4-0.91.7-2.42.3
Delay discount hyperbolic model param4.54.86.7-2.6-2.6-1.72.4-1.21.9-2.32.4
Fecal boli incidents, locomotor time 11.41.53.71.20.81.90.2-0.5-1.91.0-1.3
Change in fecal boli incidents, locomotor task0.80.81.8-0.5-0.8-1.30.4-0.01.3-0.71.1
Time >=10cm from walls, locomotor time 10.50.51.6-0.2-0.60.81.20.6-0.7-0.60.3
Bouts of movement, locomotor time 10.30.30.8-0.2-0.5-0.10.50.50.3-0.90.7
Total resting periods, locomotor time 10.10.10.40.2-0.20.50.40.6-0.3-0.40.2
Rest time, locomotor task time 10.30.31.10.1-0.31.00.5-0.5-0.8-0.50.1
Distance moved, locomotor task time 10.91.02.0-1.2-0.9-1.40.30.31.4-0.71.0
Vertical activity count, locomotor time 11.41.53.3-1.5-1.3-1.01.0-1.80.9-0.51.1
Time >=10cm from walls, locomotor time 20.20.20.8-0.4-0.70.10.9-0.0-0.3-0.20.6
Bouts of movement, locomotor time 20.70.83.90.20.5-0.1-1.22.0-0.1-0.80.2
Total resting periods, locomotor time 21.01.14.60.70.90.4-1.42.1-0.6-0.5-0.3
Rest time, locomotor task time 20.40.50.91.00.50.9-0.50.4-1.00.8-0.5
Distance moved, locomotor task time 21.11.21.9-1.4-1.2-1.10.7-0.21.3-1.21.3
Vertical activity count, locomotor time 21.31.42.3-1.4-1.5-0.61.2-1.00.6-1.21.5
Weight adjusted by age0.40.41.2-0.6-0.7-1.00.3-0.11.1-0.10.6
Seeking ratio, delayed vs. immediate footshock0.30.42.10.40.6-0.2-1.40.00.10.7-0.3
Locomotion in novel chamber1.51.84.0-0.10.6-2.0-1.8-1.51.51.50.3
Locomotion in novel chamber post-restriction1.21.44.71.41.70.1-2.20.8-0.30.9-0.9
Progressive ratio0.20.30.60.20.20.70.2-0.5-0.80.6-0.6
Food seeking constrained by brief footshock0.30.41.70.40.40.40.41.3-0.5-0.3-0.5
Seeking ratio, punishment vs. effort0.20.21.20.40.40.2-0.01.1-0.1-0.3-0.2
Run reversals in cocaine runway, females1.11.13.0-1.1-0.5-1.70.0-1.11.4-0.20.9
Run reversals in cocaine runway, males0.20.20.40.60.20.30.40.50.20.3-0.6
Latency to leave start box in cocaine runway0.80.92.3-0.7-0.7-0.60.51.20.9-1.50.9
Latency to leave start box in cocaine runway, F0.50.63.50.40.60.1-0.31.90.1-0.2-0.6
Latency to leave start box in cocaine runway, M2.62.55.2-1.5-1.9-1.11.1-0.01.3-2.22.3
Cd content in liver0.50.51.7-0.6-0.2-1.30.20.80.8-0.20.8
Co content in liver0.10.10.40.10.20.0-0.00.6-0.30.4-0.3
Cu content in liver2.12.56.71.51.90.1-2.60.4-0.52.3-1.5
Fe content in liver2.32.75.9-2.0-2.1-0.82.40.40.8-1.42.1
K content in liver0.70.71.10.90.71.0-0.20.9-0.90.6-1.0
Mg content in liver0.40.40.90.70.30.90.10.7-0.80.4-0.6
Mn content in liver0.20.20.60.60.6-0.3-0.80.10.5-0.1-0.1
Na content in liver0.20.20.90.20.3-0.0-0.40.0-0.20.9-0.4
Rb content in liver0.20.20.40.50.30.60.2-0.2-0.40.5-0.6
Se content in liver0.80.93.2-0.20.3-1.8-1.10.61.40.60.3
Sr content in liver2.11.95.91.11.6-0.4-2.4-0.60.02.0-1.0
Zn content in liver0.60.71.50.80.9-0.0-1.20.8-0.21.2-0.7