Hub : Genes

Myof

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016117 0.3 0.09 0.0e+00 0.18 0.23 0.22 0.22 6.2e-20 3.3e-25 1.5e-24 5.4e-24
2 Adipose mRNA stability ENSRNOG00000016117 0.08 0.04 7.8e-10 0.09 0.07 0.08 0.09 1.5e-10 1.9e-08 2.8e-09 1.0e-09
3 BLA gene expression ENSRNOG00000016117 0.08 0.04 9.6e-05 0.04 0.06 0.04 0.05 2.9e-03 2.3e-04 2.6e-03 8.4e-04
4 Brain gene expression ENSRNOG00000016117 0.13 0.05 1.1e-16 0.15 0.17 0.16 0.17 6.4e-14 1.3e-15 1.9e-14 2.3e-15
5 Brain mRNA stability ENSRNOG00000016117 0.08 0.05 4.0e-07 0.04 0.07 0.07 0.06 7.5e-05 4.8e-07 4.0e-07 7.1e-06
6 IL gene expression ENSRNOG00000016117 0.5 0.14 2.6e-09 0.34 0.32 0.31 0.32 4.5e-09 1.9e-08 2.8e-08 2.2e-08
7 Liver gene expression ENSRNOG00000016117 0.03 0.02 2.8e-03 0.01 0 0 0 3.1e-02 7.6e-02 7.7e-02 1.2e-01
8 NAcc gene expression ENSRNOG00000016117 0.05 0.03 3.7e-04 0.06 0.04 0.04 0.04 5.4e-05 2.8e-04 5.8e-04 3.8e-04
9 NAcc mRNA stability ENSRNOG00000016117 0.05 0.03 5.2e-04 0.05 0.04 0.04 0.04 1.3e-04 3.7e-04 5.6e-04 3.1e-04
10 OFC gene expression ENSRNOG00000016117 0.28 0.11 5.6e-04 0.2 0.13 0.13 0.15 1.6e-05 4.7e-04 6.9e-04 2.1e-04
11 PL gene expression ENSRNOG00000016117 0.35 0.1 0.0e+00 0.28 0.31 0.3 0.29 2.9e-21 2.7e-24 4.5e-23 1.4e-22
12 PL mRNA stability ENSRNOG00000016117 0.06 0.03 5.9e-04 0.03 0.03 0.03 0.03 2.5e-03 1.4e-03 1.4e-03 1.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.51.52.51.11.31.31.30.71.40.61.21.41.41.61.3
BMI without tail1.22.54.82.21.81.71.51.21.71.61.71.71.11.21.3
Body weight0.21.01.90.80.81.31.31.30.91.41.21.0-0.20.80.6
Epididymis fat weight0.30.81.60.90.81.00.91.31.00.71.11.00.40.30.5
Glucose0.10.21.30.30.40.40.1-0.40.00.7-0.20.0-1.1-0.3-0.2
Heart weight0.91.43.40.2-1.1-0.4-0.8-1.7-1.10.8-0.8-1.0-1.8-1.5-1.6
Left kidney weight0.30.94.2-0.7-0.9-0.3-0.5-0.3-0.90.7-0.5-0.9-2.1-0.9-1.3
Right kidney weight1.33.77.9-1.7-2.0-1.4-1.6-1.2-2.1-0.1-1.9-2.1-2.8-2.2-2.5
Tail length0.31.03.51.20.40.90.71.10.41.90.70.4-1.6-0.7-0.1
Length with tail0.20.73.8-0.4-0.70.10.10.8-0.50.9-0.0-0.5-2.0-0.9-0.8
Length without tail0.30.72.7-1.4-1.0-0.4-0.30.4-0.8-0.2-0.4-0.8-1.7-0.5-0.6
Liver weight, left0.30.53.3-0.5-0.00.40.41.1-0.10.8-0.1-0.1-1.8-0.4-0.6
Liver weight, right0.20.32.3-0.3-0.30.0-0.10.1-0.30.00.2-0.3-1.5-0.8-0.4
Parametrial fat weight0.40.72.8-0.5-1.0-0.3-0.5-1.2-0.60.1-0.3-0.5-1.7-1.2-1.0
Retroperitoneal fat weight0.10.20.8-0.0-0.80.20.1-0.4-0.20.4-0.4-0.1-0.4-0.9-0.5
Intraocular pressure0.10.20.5-0.4-0.6-0.20.00.3-0.5-0.0-0.4-0.60.70.0-0.1
Extensor digitorum longus weight0.20.71.10.41.11.01.00.80.80.60.90.8-0.20.31.1
Soleus weight1.13.15.01.71.92.22.21.21.82.02.11.80.31.41.6
Tibialis anterior weight0.62.24.01.11.71.51.61.81.50.91.61.60.51.12.0
Tibia length0.10.41.3-0.5-0.6-0.4-0.5-0.2-0.60.0-0.3-0.6-1.2-0.8-1.0
Number of licking bursts0.91.13.2-0.9-1.0-1.4-1.10.2-1.0-1.8-0.7-0.91.6-0.4-0.3
Food consumed during 24 hour testing period0.20.30.80.2-0.5-0.2-0.5-0.3-0.50.6-0.4-0.4-0.9-0.6-0.8
Times rat made contact with spout0.80.91.91.11.00.50.61.01.0-0.21.21.11.40.61.3
Mean time between licks in bursts0.50.72.6-0.2-0.4-0.6-0.9-1.6-0.4-0.3-0.6-0.4-1.2-1.0-1.2
Mean num. licks in bursts1.92.33.41.81.81.81.60.51.81.81.61.7-0.60.91.2
Std. dev. time between licks in bursts2.53.05.0-1.5-1.7-1.8-1.8-2.2-1.7-1.6-1.7-1.7-0.4-2.0-1.9
Water consumed over 24 hours1.51.83.01.71.51.01.01.51.50.71.41.51.10.91.6
Indifference point 0 sec0.50.91.9-0.9-0.9-0.9-0.9-0.3-1.1-0.5-1.0-1.0-0.8-1.1-1.4
Indifference point AUC3.13.66.0-2.0-2.3-2.1-1.9-1.7-2.3-1.6-1.7-2.5-0.4-2.0-1.5
Indifference point function ln k3.85.37.92.32.82.62.42.32.72.52.12.70.12.31.7
Indifference point function log k3.85.37.92.32.82.62.42.32.72.52.12.70.12.31.7
Delay discounting total patch changes 0 sec0.50.81.9-0.8-0.7-0.8-0.8-0.3-1.0-0.4-0.9-0.9-0.9-1.0-1.4
Delay discounting total patch changes 12 sec3.54.76.0-2.1-2.4-2.5-2.3-2.1-2.4-2.4-2.2-2.4-0.2-2.1-1.9
Delay discounting total patch changes 18 sec0.50.71.5-0.8-0.9-1.1-0.9-0.6-0.9-1.2-0.5-1.00.7-0.6-0.5
Delay discounting total patch changes 24 sec0.60.81.7-0.7-0.9-0.8-0.8-0.1-0.9-0.4-0.6-0.9-1.3-1.3-1.0
Delay discounting total patch changes 6 sec3.14.76.5-1.9-2.5-2.3-2.3-1.7-2.5-1.5-2.4-2.5-1.2-2.3-2.4
Delay discounting time to switch 0 sec0.81.33.8-1.3-1.3-1.4-1.2-0.5-1.0-2.0-0.9-1.10.9-0.5-0.7
Delay discounting water rate 0 sec1.21.94.61.61.71.51.30.91.52.11.31.5-0.60.81.0
Delay discounting water rate 12 sec0.60.93.11.00.71.10.80.70.91.81.10.9-1.00.50.3
Delay discounting water rate 18 sec1.62.13.91.51.51.61.41.51.52.01.61.6-0.91.01.0
Delay discounting water rate 24 sec0.71.02.30.70.91.11.11.51.11.11.01.2-0.20.80.7
Delay discounting water rate 6 sec0.10.20.90.50.40.40.30.10.40.90.30.4-0.20.20.1
Locomotor activity0.30.41.40.60.80.30.31.20.90.10.60.90.60.60.4
Locomotor testing distance0.40.61.70.70.90.40.31.31.00.20.61.10.60.80.5
Locomotor testing rearing1.21.94.00.81.61.11.32.01.60.61.41.60.61.61.4
Light reinforcement 10.20.31.2-0.8-0.4-0.30.10.7-0.3-0.8-0.2-0.31.10.40.2
Light reinforcement 20.91.13.6-0.7-0.9-1.2-1.0-1.0-0.8-1.8-0.8-0.91.9-0.3-0.1
Reaction time number correct2.33.25.51.11.71.71.82.32.10.92.22.11.02.21.7
Reaction time mean minus median0.50.72.81.00.30.70.2-0.30.41.6-0.40.2-1.7-0.1-0.8
Reaction time mean minus median AUC0.30.41.60.60.30.3-0.1-0.50.30.9-0.40.1-1.3-0.2-0.9
Reaction time num false alarms0.30.41.0-0.8-1.0-0.3-0.10.4-0.6-0.2-0.1-0.6-1.0-0.8-0.4
Reaction time num false alarms AUC0.30.51.6-0.6-1.1-0.3-0.30.3-0.7-0.1-0.1-0.7-1.2-0.9-0.6
Reaction time trials correct on left2.33.25.51.11.71.71.82.32.10.92.22.11.02.21.7
Reaction time trials on left2.23.15.31.11.61.61.82.32.00.92.12.10.92.11.7
Reaction time mean1.21.63.4-0.1-0.8-0.8-1.3-1.8-1.0-0.1-1.3-1.2-1.8-1.8-1.6
Reaction time mean AUC1.72.24.7-0.4-1.1-1.1-1.6-2.2-1.3-0.4-1.6-1.5-1.8-2.0-1.8
Median of all reaction times1.31.74.0-0.3-0.9-1.0-1.4-2.0-1.2-0.5-1.2-1.3-1.4-1.9-1.5
Reaction time omissions0.81.04.91.40.50.90.30.00.81.50.50.8-2.2-0.3-0.6
Reaction time false alarm rate1.21.73.0-1.3-1.7-1.0-1.0-0.7-1.6-0.6-1.1-1.6-1.4-1.7-1.3
Reaction time premature initiation rate0.91.35.1-1.0-1.0-0.7-0.8-0.3-1.00.0-0.8-1.1-2.3-1.4-1.4
Reaction time premature initiations0.30.43.3-0.3-0.10.30.20.90.10.60.40.1-1.8-0.1-0.5
Std. dev. reaction times0.91.35.90.6-0.4-0.0-0.7-1.2-0.41.0-1.0-0.5-2.4-1.3-1.7
Reaction time trials completed2.23.15.31.11.61.61.82.32.00.92.12.10.92.11.7
Reaction time trials AUC1.92.84.81.11.51.51.62.21.90.82.12.00.91.91.6
Social response proportion2.73.04.21.72.01.71.71.21.81.11.52.01.72.01.9
Social responses0.60.71.40.51.01.11.20.50.60.70.20.71.11.00.9
Social time0.70.91.8-1.0-0.9-1.0-1.0-0.9-1.0-0.9-1.3-1.0-0.1-0.9-0.8
Conditioned locomotion0.10.10.3-0.20.10.20.20.30.3-0.00.50.2-0.3-0.0-0.2
Cocaine response after cond. corrected0.20.20.3-0.2-0.5-0.4-0.5-0.2-0.60.0-0.4-0.6-0.3-0.4-0.5
Cocaine response after cond. not corrected0.10.10.1-0.0-0.3-0.3-0.30.2-0.40.0-0.1-0.4-0.4-0.2-0.2
Cocaine response before conditioning0.00.10.20.20.10.00.10.20.2-0.20.30.20.10.10.5
Saline control response2.33.08.1-2.6-1.6-2.0-1.6-1.2-1.6-2.9-1.5-1.60.3-1.5-0.9
Condit. Reinf. active minus inactive responses2.42.94.41.91.61.81.82.11.81.42.01.80.91.51.8
Condit. Reinf. active-inactive response ratio1.51.62.21.31.31.11.11.41.20.71.51.21.31.31.4
Condit. Reinf. active responses0.40.51.20.50.41.01.11.10.60.80.90.6-0.20.40.5
Condit. Reinf. inactive responses1.01.23.1-1.2-1.3-0.5-0.5-0.7-1.2-0.1-1.1-1.2-1.8-1.4-1.3
Condit. Reinf. lever presses0.20.30.6-0.5-0.8-0.5-0.4-0.0-0.7-0.7-0.4-0.70.0-0.5-0.5
Condit. Reinf. lever reinforcers received0.20.20.80.20.20.60.70.90.40.30.60.4-0.10.20.4
Pavlov. Cond. lever latency1.42.03.11.21.81.31.30.91.61.11.51.60.71.71.6
Pavlov. Cond. magazine entry latency0.30.31.50.6-0.3-0.1-0.5-0.1-0.10.4-0.2-0.1-1.2-0.8-0.7
Pavlov. Cond. change in total contacts0.50.71.7-0.5-1.1-0.8-0.9-0.4-0.9-0.7-0.7-0.9-0.8-1.3-0.9
Pavlov. Cond. index score0.70.91.8-0.4-1.2-0.8-0.9-0.3-1.0-0.4-0.9-1.0-1.1-1.3-1.1
Pavlov. Cond. latency score0.50.61.2-0.3-1.0-0.6-0.8-0.1-0.8-0.2-0.6-0.8-1.1-1.1-1.0
Pavlov. Cond. lever contacts1.21.62.5-1.2-1.6-1.2-1.1-0.7-1.5-1.1-1.3-1.5-0.7-1.6-1.4
Pavlov. Cond. magazine entry number2.02.44.60.81.61.41.81.21.50.81.61.51.82.11.8
Pavlov. Cond. intertrial magazine entries1.11.52.20.91.41.11.31.51.20.81.11.20.81.41.5
Pavlov. Cond. lever-magazine prob. diff.0.50.71.4-0.2-1.0-0.7-0.9-0.1-0.9-0.4-0.7-0.9-1.1-1.2-1.0
Pavlov. Cond. response bias1.21.63.2-0.8-1.5-1.2-1.3-0.7-1.4-0.9-1.3-1.4-1.1-1.8-1.5
Conditioned reinforcement - actives0.90.91.80.50.90.90.91.30.81.11.10.9-0.51.30.7
Conditioned reinforcement - inactives3.43.96.01.81.82.02.02.22.02.51.72.10.22.41.9
Conditioned locomotion0.10.21.10.20.10.50.5-0.10.11.1-0.10.1-0.50.30.1
Intermittent access intake day 1-15 change3.73.75.31.72.12.12.01.52.22.32.32.2-0.42.11.2
Intermittent access intake escalation3.02.94.81.51.81.81.71.41.92.12.21.9-0.61.90.8
Intermittent access intake escalation 24.44.47.32.02.32.11.91.62.52.22.72.5-0.12.51.4
Intermitt. access day 1 inactive lever presses0.20.20.50.70.30.50.40.10.50.00.50.50.60.30.4
Intermitt. access day 15 inactive lever presses0.60.71.30.90.71.11.20.00.71.00.50.80.50.70.9
Intermitt. access escalation Index1.00.92.21.31.20.90.7-0.41.50.50.91.5-0.10.60.8
Intermittent access day 1 total infusions0.70.81.90.90.81.11.10.80.81.4-0.20.9-0.10.70.9
Intermittent access day 15 total infusions2.93.38.51.71.82.21.91.21.82.91.31.9-1.41.80.9
Intermittent access terminal intake (last 3 days)2.93.26.71.81.92.01.91.12.02.61.52.0-0.71.91.3
Intermittent access total infusions1.71.94.11.41.41.71.61.01.52.00.71.5-0.61.51.1
Intermittent access day 1 locomotion0.20.20.70.60.00.50.30.1-0.10.8-0.5-0.0-0.8-0.20.0
Intermittent access day 15 total locomotion0.20.21.3-0.7-0.5-0.10.1-0.1-0.50.2-1.1-0.4-0.5-0.0-0.4
Intermittent access total locomotion0.10.10.4-0.3-0.20.10.20.3-0.2-0.0-0.6-0.10.00.10.2
Intermittent access standard deviation3.53.77.42.31.92.21.81.22.12.72.12.1-1.11.71.1
Cocaine induced anxiety0.40.50.90.60.80.30.30.61.0-0.50.50.90.70.70.9
Post-drug Anxiety0.80.93.7-1.1-0.7-1.0-0.8-0.7-0.6-1.9-0.7-0.61.4-0.5-0.2
Baseline Anxiety1.01.11.8-1.1-1.3-0.9-0.8-1.1-1.3-0.9-0.7-1.30.2-1.3-1.0
Lifetime Intake0.91.02.30.81.01.31.30.91.01.50.11.1-0.31.20.9
Incentive Sensitization - Responses4.84.87.01.82.22.42.52.12.52.22.12.50.32.61.9
Incentive Sensitization - Breakpoint4.34.36.21.72.12.32.42.02.42.22.02.40.22.51.8
Progressive ratio test 1 active lever presses0.80.91.50.61.01.11.20.70.90.70.41.00.61.21.1
Progressive ratio test 1 breakpoint0.90.91.60.81.11.11.20.61.00.70.61.00.71.21.2
Progressive ratio test 1 inactive lever presses3.33.55.21.91.92.22.31.62.01.71.62.11.11.92.1
Progressive ratio test 2 active lever presses2.83.05.01.11.82.02.21.91.91.71.12.00.22.21.6
Progressive ratio test 2 breakpoint3.64.06.31.42.12.32.52.02.31.91.52.30.42.51.9
Progressive ratio test 2 inactive lever presses2.52.95.61.11.71.82.01.71.81.41.01.91.22.41.8
Total sessions with >9 infusions0.10.10.2-0.5-0.30.10.40.2-0.40.1-0.4-0.30.40.20.2
Short access day 1 total inactive lever presses3.03.38.11.41.71.72.01.21.80.70.61.92.82.52.2
Short access day 10 total inactive lever presses0.30.30.80.50.3-0.2-0.3-0.90.5-0.90.60.50.8-0.10.4
Short access day 1 total infusions0.20.20.9-0.8-0.4-0.3-0.1-0.1-0.5-0.5-0.9-0.40.60.1-0.1
Short access day 10 total infusions0.30.31.5-0.1-0.5-0.1-0.2-0.6-0.50.4-1.2-0.4-0.8-0.7-0.6
Short access total infusions0.20.20.5-0.10.20.50.70.60.20.6-0.60.30.30.60.5
Short access day 1 locomotion0.20.21.2-0.30.10.10.30.30.1-0.40.40.11.10.50.6
Short access day 10 total locomotion0.00.00.10.2-0.3-0.0-0.10.1-0.2-0.3-0.1-0.20.1-0.10.0
Short access total locomotion0.20.20.8-0.3-0.4-0.3-0.2-0.3-0.3-0.9-0.4-0.30.8-0.20.2
Compulsive drug intake2.62.64.62.21.81.81.40.32.01.82.12.0-0.70.91.2
One hour access (0.3 mA shock)6.57.610.52.32.83.13.22.83.03.02.63.0-0.13.22.3
One hour access (shock baseline)1.01.22.30.71.01.21.31.51.01.30.71.1-0.21.40.8
Number of responses in last shaping day0.40.41.2-0.20.50.60.80.20.5-0.20.20.51.11.10.4
Context. condit. distance diff. score1.41.83.10.81.41.41.61.51.31.31.81.30.41.31.4
Locomotion velocity, session 11.11.22.0-0.9-1.1-1.4-1.3-1.0-1.2-1.3-1.1-1.30.7-0.7-0.8
Locomotion distance, session 10.50.71.5-1.2-0.9-0.9-0.6-0.1-1.0-0.9-1.0-1.00.5-0.4-0.5
Locomotion velocity, session 20.60.71.31.11.00.50.40.70.90.91.10.90.51.21.0
Locomotion distance, session 20.10.11.1-0.30.1-0.2-0.11.0-0.1-0.0-0.1-0.10.00.30.2
Locomotion velocity, session 30.40.40.80.40.90.60.60.90.70.50.80.7-0.50.60.4
Locomotion distance, session 30.60.62.60.50.60.80.60.90.61.20.30.5-1.60.20.0
Stereotopy head waving bouts, day 30.40.51.90.30.60.50.60.40.50.40.80.61.40.90.7
Stereotopy head waving duration, day 30.60.73.60.60.60.50.70.20.60.20.80.61.90.91.1
Locomotion velocity, session 72.73.04.52.11.92.01.81.61.91.71.91.80.21.11.8
Locomotion distance, session 71.62.03.82.01.51.71.51.21.51.71.51.5-0.40.71.3
Stereotopy head waving bouts, day 70.30.31.60.10.40.00.20.40.40.10.60.41.31.00.6
Stereotopy head waving duration, day 70.20.30.90.30.50.30.4-0.00.50.50.70.50.80.90.4
Locomotion velocity, session 80.30.40.50.40.70.70.70.60.60.50.60.60.10.70.7
Locomotion distance, session 80.91.33.20.31.20.81.11.81.10.61.31.00.71.51.4
Degree of sensitization distance0.30.31.30.70.30.30.40.10.4-0.10.70.41.10.21.1
Degree of sensitization stereotypy0.10.10.3-0.5-0.1-0.4-0.2-0.1-0.2-0.0-0.2-0.10.20.5-0.1
Condit. Reinf. active minus inactive responses0.10.20.50.3-0.4-0.3-0.5-0.1-0.1-0.0-0.5-0.2-0.7-0.5-0.5
Condit. Reinf. active-inactive response ratio0.30.30.60.2-0.6-0.4-0.6-0.7-0.2-0.2-0.6-0.3-0.8-0.5-0.7
Condit. Reinf. active responses0.10.10.7-0.1-0.2-0.2-0.30.1-0.30.0-0.5-0.2-0.8-0.6-0.4
Condit. Reinf. inactive responses0.10.10.3-0.50.1-0.10.10.5-0.3-0.2-0.2-0.20.1-0.10.1
Incentive salience index mean0.81.01.6-0.6-1.1-1.0-1.2-0.3-0.9-0.7-1.2-1.0-1.2-1.3-1.1
Condit. Reinf. lever presses2.53.44.4-1.9-1.8-2.0-2.0-1.2-1.9-2.0-2.1-1.9-1.0-2.1-1.7
Time in familiar zone, hab. session 10.40.42.20.70.10.50.60.50.40.50.20.41.50.70.6
Time in novel zone, hab. session 10.30.30.5-0.4-0.3-0.6-0.6-0.6-0.5-0.7-0.4-0.5-0.6-0.6-0.3
Total zone transitions, hab. session 10.10.10.5-0.7-0.2-0.10.10.7-0.0-0.5-0.0-0.00.30.40.2
Total locomotion distance, hab. session 10.91.22.8-1.7-1.2-1.3-1.00.3-1.1-1.6-1.3-1.10.4-0.6-0.7
Locomotion velocity, hab. session 11.72.45.0-2.2-1.6-1.8-1.5-0.1-1.7-2.1-1.7-1.70.1-1.2-1.2
Time in familiar zone, hab. session 20.10.10.50.1-0.3-0.2-0.3-0.7-0.2-0.2-0.3-0.30.2-0.6-0.5
Time in novel zone, hab. session 20.00.00.0-0.20.1-0.0-0.00.0-0.1-0.0-0.2-0.1-0.10.10.0
Total zone transitions, hab. session 20.71.02.1-1.5-1.1-1.0-0.9-0.5-1.2-0.9-0.8-1.2-0.5-0.8-1.0
Total locomotion distance, hab. session 20.91.12.1-1.5-1.2-1.1-1.0-0.1-1.3-0.8-1.1-1.4-0.2-1.0-1.2
Locomotion velocity, hab. session 21.01.32.9-1.7-1.3-1.3-1.00.0-1.4-1.1-1.1-1.4-0.1-1.0-1.0
Novel to familiar place preference ratio4.74.96.92.22.31.92.02.52.21.62.42.21.82.62.6
Novelty place preference5.05.27.32.22.42.02.12.52.31.62.52.31.92.72.7
Time in novel zone, NPP test5.05.27.32.42.52.02.12.32.31.72.52.31.82.62.7
Total zone transitions, NPP test1.11.62.4-1.5-1.4-1.3-1.2-0.6-1.4-1.1-1.1-1.5-1.1-1.4-1.3
Total locomotion distance, NPP test1.82.53.5-1.8-1.8-1.8-1.7-0.6-1.8-1.7-1.5-1.9-0.4-1.6-1.4
Locomotion velocity, NPP test1.82.53.6-1.9-1.8-1.8-1.7-0.6-1.8-1.6-1.5-1.9-0.6-1.7-1.4
Pavlov. Cond. lever latency0.10.10.4-0.0-0.20.10.2-0.6-0.10.1-0.1-0.10.50.3-0.2
Pavlov. Cond. magazine entry latency1.11.43.8-0.4-1.1-1.0-1.4-0.6-1.0-0.2-1.2-1.1-1.9-1.6-1.6
Pavlov. Cond. change in total contacts0.40.42.40.6-0.3-0.2-0.6-0.3-0.20.6-0.4-0.2-1.6-0.7-0.8
Pavlov. Cond. index score0.50.61.9-0.5-0.7-0.8-1.00.3-0.7-0.3-0.7-0.7-1.4-1.0-0.9
Pavlov. Cond. latency score0.40.51.8-0.5-0.5-0.7-0.90.4-0.6-0.3-0.6-0.6-1.3-1.0-0.7
Pavlov. Cond. lever contacts0.70.81.4-0.9-0.8-0.9-1.0-0.0-0.8-0.8-0.8-0.8-1.1-1.2-0.8
Pavlov. Cond. magazine entry number0.40.52.3-0.40.40.20.60.00.4-0.60.60.41.51.01.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.4-0.2-0.00.10.4-0.1-0.20.1-0.10.10.0-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.9-0.5-0.7-0.9-1.10.1-0.7-0.4-0.8-0.7-1.4-1.1-1.0
Pavlov. Cond. response bias0.70.83.0-0.1-0.7-0.7-1.1-0.3-0.70.0-0.8-0.7-1.7-1.3-1.3
Bone: apparent density4.88.012.02.12.83.03.33.32.82.52.72.82.03.52.7
Bone surface3.56.18.42.42.52.82.92.62.42.72.42.51.32.72.2
Bone volume3.76.28.92.12.42.83.03.02.52.52.62.51.32.62.2
Bone: connectivity density6.29.713.23.03.33.33.52.83.22.92.93.32.33.63.1
Bone: cortical apparent density0.81.03.1-0.4-0.8-1.1-1.1-1.8-0.9-1.2-1.2-0.91.0-0.5-0.2
Bone: cortical area0.81.23.70.90.71.41.31.70.71.90.90.7-1.10.30.3
Bone: cortical porosity0.91.01.90.91.00.70.90.81.00.51.21.01.21.11.4
Bone: cortical porosity1.31.42.01.31.31.11.11.11.31.11.41.20.51.11.3
Bone: cortical thickness1.01.72.5-1.4-1.5-1.2-1.2-0.3-1.6-0.5-1.4-1.6-1.3-1.5-1.5
Bone: cortical thickness1.41.62.8-1.3-1.6-1.5-1.3-0.3-1.7-1.2-1.3-1.60.2-1.1-1.0
Bone: cortical tissue density0.81.02.8-0.4-0.8-1.1-1.0-1.7-0.8-1.3-1.2-0.81.2-0.4-0.1
Bone: elastic displacement0.60.64.80.50.5-0.0-0.0-0.90.5-0.8-0.10.42.20.40.5
Bone: elastic work1.11.45.31.41.20.80.80.01.20.20.91.22.31.11.3
Bone: endosteal estimation5.010.916.03.53.24.03.93.43.33.93.63.30.52.72.8
Bone: endosteal perimeter5.010.214.33.13.13.73.83.63.33.53.53.30.83.02.7
Bone: final force0.20.31.30.2-0.20.50.50.9-0.21.20.3-0.1-0.9-0.1-0.2
Bone: final moment0.20.31.50.3-0.20.50.50.8-0.21.20.2-0.1-0.8-0.2-0.3
Bone: marrow area5.211.216.43.53.34.14.03.43.43.93.63.40.62.82.8
Bone: maximum diameter6.111.215.92.93.33.94.03.93.43.63.73.40.63.32.8
Bone: maximum force0.91.54.11.00.81.51.61.60.82.01.20.90.01.10.9
Bone: maximum moment0.81.44.31.10.81.61.61.40.82.11.00.80.10.90.7
Bone: minimum diameter6.411.921.13.63.44.34.13.43.54.63.53.5-0.62.82.5
Bone: periosteal estimation3.46.911.62.52.43.23.33.22.43.42.82.50.02.12.0
Bone: periosteal perimeter3.76.110.12.22.32.93.03.22.42.82.72.40.42.22.0
Bone: post-yield work1.41.95.61.20.91.71.81.90.92.41.01.0-0.01.30.8
Bone: stiffness1.11.84.41.01.01.61.61.81.02.11.41.0-0.80.91.0
Bone: tissue strength0.10.10.60.40.10.40.2-0.80.10.5-0.00.1-0.3-0.3-0.2
Bone: trabecular number4.16.48.72.52.62.72.92.72.52.82.32.51.52.92.3
Bone: trabecular spacing2.33.05.2-1.1-1.7-1.7-2.0-1.9-1.7-1.4-1.4-1.7-1.7-2.3-1.8
Bone: trabecular thickness2.93.65.11.51.92.22.32.11.92.02.02.00.72.01.6
Bone: trabecular tissue density0.70.91.40.61.01.01.10.91.00.71.21.00.51.01.1
Breakpoint value in progressive ratio session0.20.20.9-1.0-0.4-0.4-0.10.3-0.6-0.8-0.3-0.5-0.2-0.4-0.0
Distance traveled before self-admin0.80.91.61.11.20.80.70.81.30.50.91.30.10.91.0
Distance traveled after self-admin3.94.36.42.22.11.92.01.52.21.81.92.22.02.32.5
Delta time in closed arm before/after self-admin0.80.71.9-0.4-0.9-0.4-0.50.1-0.90.0-0.9-1.0-1.4-1.2-1.1
Delta time in open arm before/after self-admin1.61.62.71.11.30.80.90.61.40.61.61.41.41.61.7
Diff in mean of infusions in LGA sessions1.61.83.82.01.21.51.30.91.51.11.61.6-0.20.91.3
Extinction: sum of active levers before priming0.10.10.50.0-0.10.30.40.4-0.20.60.4-0.2-0.7-0.4-0.0
Active lever presses in extinction session 64.34.18.91.22.01.82.13.01.91.12.01.91.82.42.4
Delta distance traveled before/after self-admin1.92.02.91.41.31.51.60.81.31.31.51.31.61.41.7
Delta ambulatory time before/after self-admin2.83.04.21.81.81.92.01.11.71.71.81.71.41.72.1
Time in closed arm before self-admin2.32.63.61.61.71.21.31.61.81.01.81.81.71.81.9
Time in closed arm after self-admin0.10.11.0-0.4-0.1-0.3-0.11.0-0.2-0.3-0.1-0.20.3-0.40.1
Time in open arm before self-admin0.30.30.8-0.7-0.5-0.4-0.4-0.5-0.5-0.9-0.7-0.5-0.0-0.6-0.7
Time in open arm after self-admin0.20.20.80.00.50.20.30.30.5-0.10.60.40.70.90.4
Sum of active levers in priming session hrs 5-60.10.10.30.5-0.10.10.00.10.1-0.10.40.10.50.0-0.0
Time to tail flick, vehicle, before self-admin0.70.74.1-0.5-0.4-0.6-0.4-0.7-0.3-1.5-0.3-0.32.00.20.4
Time to tail flick, vehicle, after self-admin0.70.73.30.40.60.80.91.80.70.80.90.70.10.41.0
Time to tail flick, test, before self-admin2.72.74.01.71.61.81.91.81.51.71.61.60.61.52.0
Time to tail flick, test, after self-admin1.61.72.81.61.41.00.90.71.5-0.51.41.51.70.91.6
Delta time to tail flick, vehicle, before/after SA2.12.17.80.91.21.41.52.81.21.71.41.2-1.00.81.0
Delta time to tail flick, test, before/after SA0.20.21.00.10.3-0.10.00.20.4-1.00.50.30.80.20.2
Ambulatory time before self-admin0.50.51.10.90.90.50.40.61.00.30.91.00.30.70.8
Ambulatory time after self-admin6.77.411.02.92.92.62.62.12.92.22.62.92.43.03.3
Total heroin consumption0.10.10.3-0.6-0.4-0.00.10.3-0.4-0.3-0.3-0.4-0.2-0.2-0.1
Area under the delay curve0.30.31.2-0.6-0.3-0.7-0.50.2-0.2-1.10.0-0.31.1-0.20.1
Delay disc. indifference point, 0s delay2.02.24.41.21.51.01.11.51.80.22.11.71.41.41.8
Delay disc. indifference point, 16s delay0.20.20.6-0.8-0.3-0.6-0.3-0.2-0.5-0.6-0.2-0.40.6-0.3-0.0
Delay disc. indifference point, 2s delay0.40.43.50.20.2-0.00.20.40.3-0.50.40.21.90.40.7
Delay disc. indifference point, 24s delay0.80.71.3-0.8-0.9-1.1-1.0-0.8-1.1-0.6-0.6-1.1-0.1-1.1-0.6
Delay disc. indifference point, 4s delay0.30.31.4-0.5-0.2-0.7-0.40.4-0.3-1.0-0.3-0.21.2-0.00.4
Delay disc. indifference point, 8s delay1.81.85.1-1.4-1.3-1.8-1.5-0.8-1.2-2.3-0.8-1.30.9-1.3-0.9
Delay discount exponential model param0.30.31.20.60.40.80.5-0.20.41.10.10.4-1.00.3-0.0
Delay discount hyperbolic model param0.30.31.30.40.20.70.4-0.20.21.0-0.00.3-1.10.2-0.1
Fecal boli incidents, locomotor time 11.21.32.61.01.41.11.11.10.90.61.11.21.01.21.6
Change in fecal boli incidents, locomotor task1.11.11.6-1.3-1.3-1.1-1.1-0.8-0.9-0.9-0.9-1.0-0.8-1.0-1.2
Time >=10cm from walls, locomotor time 11.01.110.50.2-0.10.50.2-0.20.21.20.0-0.0-3.2-0.4-0.4
Bouts of movement, locomotor time 10.30.41.5-0.80.5-0.00.41.20.2-0.20.80.30.80.70.2
Total resting periods, locomotor time 10.30.41.3-0.90.3-0.20.31.20.0-0.30.80.20.70.70.3
Rest time, locomotor task time 11.51.74.00.21.40.50.91.41.0-0.21.81.32.01.51.5
Distance moved, locomotor task time 11.51.75.2-0.1-1.3-0.6-1.0-1.3-1.10.2-1.4-1.3-2.3-1.9-1.4
Vertical activity count, locomotor time 11.51.65.0-0.2-1.3-0.7-1.1-1.2-1.10.3-1.0-1.2-2.2-1.5-1.7
Time >=10cm from walls, locomotor time 20.40.42.00.80.60.40.10.20.90.30.60.7-1.40.00.3
Bouts of movement, locomotor time 21.01.12.8-1.2-1.0-1.7-1.4-0.5-0.9-1.5-0.6-1.01.0-0.5-0.4
Total resting periods, locomotor time 20.91.02.6-1.3-0.9-1.6-1.3-0.2-0.8-1.5-0.4-0.81.0-0.4-0.3
Rest time, locomotor task time 20.40.51.8-1.4-0.3-0.7-0.21.1-0.5-1.00.4-0.30.80.40.2
Distance moved, locomotor task time 20.60.72.41.40.30.90.3-0.60.71.10.30.5-1.5-0.6-0.0
Vertical activity count, locomotor time 20.50.62.81.70.30.5-0.1-1.00.50.80.30.5-1.1-0.6-0.2
Weight adjusted by age0.50.64.4-0.20.4-0.10.20.60.2-1.00.50.32.10.60.7
Seeking ratio, delayed vs. immediate footshock0.10.20.7-0.6-0.4-0.3-0.20.0-0.3-0.10.1-0.3-0.9-0.5-0.4
Locomotion in novel chamber3.74.67.71.42.12.12.32.42.31.72.52.11.52.82.2
Locomotion in novel chamber post-restriction0.30.31.6-1.1-0.3-0.10.31.2-0.60.2-0.0-0.5-0.10.40.2
Progressive ratio0.20.30.8-0.9-0.3-0.2-0.20.7-0.2-0.4-0.5-0.3-0.7-0.6-0.8
Food seeking constrained by brief footshock0.70.93.9-0.5-0.10.40.41.6-0.01.8-0.5-0.0-2.00.1-0.6
Seeking ratio, punishment vs. effort0.10.21.00.4-0.00.20.20.3-0.01.00.20.0-0.70.20.1
Run reversals in cocaine runway, females0.20.21.40.0-0.3-0.2-0.10.1-0.2-0.60.2-0.31.20.10.1
Run reversals in cocaine runway, males3.02.95.7-2.0-2.0-1.7-1.6-1.3-2.0-1.1-2.4-2.0-1.0-1.4-1.6
Latency to leave start box in cocaine runway2.02.23.01.41.71.71.71.31.61.41.71.70.61.31.2
Latency to leave start box in cocaine runway, F3.43.84.91.92.12.12.11.62.21.92.12.21.01.81.9
Latency to leave start box in cocaine runway, M0.10.10.30.10.20.30.20.40.10.00.50.1-0.3-0.2-0.4
Cd content in liver1.71.93.5-0.8-1.5-1.2-1.3-1.5-1.4-0.6-1.5-1.5-1.4-1.6-1.9
Co content in liver0.40.51.5-0.1-0.7-0.7-0.8-1.2-0.5-0.5-0.7-0.6-0.1-0.9-1.0
Cu content in liver4.04.88.3-2.2-2.3-2.6-2.3-2.2-2.3-2.9-2.4-2.30.7-1.7-1.6
Fe content in liver2.02.43.9-1.5-1.4-1.9-2.0-1.7-1.5-1.9-1.6-1.5-0.0-1.2-1.4
K content in liver0.30.31.4-0.9-0.1-0.6-0.50.3-0.1-1.20.2-0.10.60.10.3
Mg content in liver0.80.82.4-1.4-0.7-1.3-1.1-0.4-0.8-1.6-0.6-0.80.2-0.5-0.5
Mn content in liver2.12.45.2-2.0-1.6-2.0-1.7-0.7-1.6-2.3-1.4-1.60.9-0.6-0.8
Na content in liver1.41.53.7-1.7-1.1-1.6-1.4-0.6-1.3-1.9-1.2-1.20.4-0.6-0.4
Rb content in liver0.10.10.50.40.30.40.30.70.30.30.50.4-0.30.00.3
Se content in liver17.120.731.2-4.3-4.5-5.5-5.3-4.5-4.8-5.6-4.8-4.70.3-3.9-3.8
Sr content in liver0.20.10.80.3-0.20.20.1-0.90.00.60.20.0-0.5-0.0-0.2
Zn content in liver2.02.24.5-0.7-1.3-1.8-2.0-2.0-1.3-2.1-1.2-1.30.2-1.7-1.0