Hub : Genes

Rb1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000016029 0.21 0.12 0.0e+00 0.1 0.16 0.16 0.16 1.6e-11 1.7e-17 2.1e-17 6.6e-17
2 Adipose mRNA stability ENSRNOG00000016029 0.09 0.05 1.5e-09 0.08 0.08 0.08 0.08 1.3e-09 7.7e-09 1.5e-09 1.6e-09
3 BLA gene expression ENSRNOG00000016029 0.21 0.11 4.6e-06 0.08 0.1 0.12 0.09 3.8e-05 4.1e-06 6.7e-07 1.2e-05
4 BLA mRNA stability ENSRNOG00000016029 0.1 0.08 1.3e-03 0.07 0.03 0.04 0.04 1.5e-04 7.2e-03 3.7e-03 3.6e-03
5 Brain gene expression ENSRNOG00000016029 0.14 0.07 6.2e-14 0.09 0.16 0.15 0.16 3.0e-08 3.4e-14 4.7e-14 2.1e-14
6 Brain mRNA stability ENSRNOG00000016029 0.14 0.07 1.8e-12 0.09 0.13 0.13 0.12 1.4e-08 2.7e-12 3.8e-12 1.2e-11
7 IL gene expression ENSRNOG00000016029 0.19 0.11 2.4e-03 0.05 0.02 0.01 0.03 2.6e-02 1.0e-01 2.1e-01 5.2e-02
8 LHb gene expression ENSRNOG00000016029 0.21 0.13 3.4e-03 0.16 0.07 0.11 0.12 1.3e-04 1.1e-02 1.7e-03 7.3e-04
9 Liver gene expression ENSRNOG00000016029 0.06 0.04 2.2e-07 0.04 0.05 0.05 0.04 2.7e-05 2.0e-06 7.6e-06 1.0e-05
10 Liver intron excision ratio chr15:48393920:48441211 0.05 0.04 9.5e-03 0.01 0 -0 0.01 1.8e-02 9.4e-02 5.5e-01 3.6e-02
11 Liver mRNA stability ENSRNOG00000016029 0.06 0.04 5.4e-07 0.05 0.05 0.04 0.05 3.1e-06 1.1e-06 1.1e-05 4.9e-06
12 NAcc gene expression ENSRNOG00000016029 0.1 0.05 2.8e-07 0.06 0.08 0.07 0.07 4.5e-05 1.4e-06 7.7e-06 1.2e-05
13 OFC gene expression ENSRNOG00000016029 0.18 0.11 2.2e-03 0.1 0.06 0.04 0.06 2.6e-03 1.4e-02 5.3e-02 1.4e-02
14 PL gene expression ENSRNOG00000016029 0.11 0.06 5.6e-08 0.03 0.09 0.08 0.07 2.3e-03 2.3e-07 9.8e-07 2.2e-06
15 PL mRNA stability ENSRNOG00000016029 0.05 0.04 9.8e-03 0.01 0.01 0.02 0 5.8e-02 1.1e-01 1.3e-02 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.10.30.9-0.6-0.20.10.10.70.90.60.7-0.3-0.9-0.50.90.10.50.1
BMI without tail0.91.93.3-1.4-1.51.21.41.01.81.41.2-1.2-1.6-1.41.61.31.21.1
Body weight0.10.41.4-0.3-0.80.50.7-0.4-0.21.2-0.9-0.7-0.9-0.4-0.30.80.00.7
Epididymis fat weight1.43.26.5-1.7-2.52.02.50.81.31.90.5-2.1-0.5-2.01.12.51.52.0
Glucose0.50.82.3-0.70.4-0.1-0.41.01.50.61.40.0-1.2-0.31.4-0.40.5-1.4
Heart weight0.10.10.20.2-0.30.30.4-0.4-0.1-0.1-0.40.1-0.20.1-0.20.3-0.30.2
Left kidney weight0.72.14.6-0.3-2.12.02.0-1.0-0.01.4-1.4-1.1-1.9-0.8-0.42.2-0.12.0
Right kidney weight1.54.414.1-0.0-2.83.02.7-1.8-0.51.4-2.2-1.3-2.4-0.8-1.02.8-0.53.8
Tail length0.51.54.3-0.5-1.81.41.6-0.70.41.5-0.7-1.0-2.1-0.80.01.7-0.01.6
Length with tail0.10.52.50.3-0.50.20.5-0.9-1.10.4-1.6-0.30.20.1-1.20.5-0.40.8
Length without tail0.91.94.41.31.4-1.0-1.2-1.0-2.1-1.4-1.61.01.91.3-1.8-1.3-1.0-0.6
Liver weight, left0.40.72.80.50.7-1.4-0.6-0.1-0.9-0.3-0.50.41.70.5-0.7-0.7-0.3-1.3
Liver weight, right0.20.41.60.30.9-1.2-0.7-0.0-0.00.10.10.5-0.20.4-0.1-0.9-0.3-1.3
Parametrial fat weight1.32.63.7-1.9-1.51.31.61.81.81.31.6-1.80.3-1.91.91.61.90.9
Retroperitoneal fat weight0.51.82.9-1.5-1.51.11.61.41.11.10.9-1.70.5-1.61.21.51.60.6
Intraocular pressure0.50.72.3-1.1-0.8-0.30.80.70.71.50.6-1.10.2-1.00.70.80.9-0.5
Extensor digitorum longus weight4.317.329.24.15.4-4.7-5.4-2.2-3.6-5.1-1.64.92.34.7-3.1-5.4-3.5-3.6
Soleus weight2.77.914.72.33.8-3.6-3.8-0.6-2.0-3.6-0.33.12.62.8-1.5-3.8-1.7-3.2
Tibialis anterior weight2.89.816.03.34.0-3.5-3.9-2.0-2.8-3.6-1.73.70.93.6-2.6-4.0-2.9-2.3
Tibia length2.15.912.1-0.8-3.33.13.4-1.6-0.13.5-2.4-2.2-3.0-1.5-0.73.3-0.12.8
Number of licking bursts1.01.22.6-1.3-0.80.91.01.11.21.61.0-1.2-0.3-1.21.20.81.20.6
Food consumed during 24 hour testing period0.40.52.30.6-0.30.60.3-1.2-0.20.2-0.90.4-1.50.4-0.50.3-0.9-0.0
Times rat made contact with spout2.93.36.1-1.8-1.81.91.91.12.02.51.0-1.8-2.0-1.81.71.81.42.4
Mean time between licks in bursts0.10.20.7-0.2-0.60.10.60.10.40.20.3-0.3-0.2-0.40.30.60.3-0.8
Mean num. licks in bursts0.20.21.60.0-0.20.30.1-0.30.20.2-0.20.1-1.30.00.10.2-0.20.9
Std. dev. time between licks in bursts0.60.71.90.5-1.20.41.2-1.4-0.90.3-1.4-0.2-0.20.1-1.11.2-0.70.1
Water consumed over 24 hours0.20.21.30.40.10.2-0.0-0.6-0.10.2-0.50.3-1.10.3-0.3-0.1-0.60.0
Indifference point 0 sec1.42.35.8-0.5-2.31.82.3-1.00.12.4-1.4-1.4-1.6-1.1-0.32.20.11.0
Indifference point AUC0.60.84.00.21.0-0.8-1.00.30.5-0.81.10.80.20.50.5-1.0-0.1-2.0
Indifference point function ln k0.60.92.7-0.3-1.31.21.3-0.5-0.30.9-1.1-0.9-0.7-0.6-0.41.20.11.6
Indifference point function log k0.60.92.7-0.3-1.31.21.3-0.5-0.30.9-1.1-0.9-0.7-0.6-0.41.20.11.6
Delay discounting total patch changes 0 sec1.22.05.8-0.5-2.11.52.2-1.00.02.4-1.4-1.3-1.5-1.0-0.42.00.00.7
Delay discounting total patch changes 12 sec0.40.51.20.3-0.60.40.7-1.0-0.21.1-0.9-0.1-1.00.1-0.50.6-0.6-1.1
Delay discounting total patch changes 18 sec0.50.72.4-1.0-0.70.30.70.60.91.50.6-1.0-0.3-0.90.90.80.8-0.3
Delay discounting total patch changes 24 sec0.40.51.80.0-0.70.20.7-0.9-0.11.3-1.0-0.3-1.3-0.1-0.40.7-0.40.8
Delay discounting total patch changes 6 sec1.62.45.6-1.7-1.71.51.81.21.52.40.9-1.9-0.5-1.81.41.71.60.8
Delay discounting time to switch 0 sec0.20.22.50.20.20.2-0.1-0.2-0.5-0.4-0.50.10.40.2-0.4-0.1-0.21.6
Delay discounting water rate 0 sec0.20.41.7-0.4-0.60.40.5-0.20.31.3-0.3-0.6-1.1-0.40.10.60.1-0.6
Delay discounting water rate 12 sec0.10.21.5-0.3-0.1-0.10.10.3-0.20.10.1-0.41.2-0.3-0.00.10.4-0.3
Delay discounting water rate 18 sec0.20.30.7-0.7-0.20.50.30.90.60.30.7-0.60.2-0.60.70.20.80.1
Delay discounting water rate 24 sec1.21.63.1-1.7-0.60.10.61.81.51.61.4-1.50.4-1.51.60.61.7-0.6
Delay discounting water rate 6 sec0.40.61.50.61.0-1.2-0.9-0.5-0.7-0.4-0.50.7-0.00.7-0.6-1.0-0.6-0.9
Locomotor activity5.79.016.63.72.2-1.6-2.1-3.9-3.9-2.4-4.13.0-0.43.4-4.1-2.2-3.8-0.1
Locomotor testing distance3.05.012.02.71.2-0.9-1.1-3.2-3.1-1.2-3.51.9-0.62.3-3.3-1.2-2.80.8
Locomotor testing rearing3.14.913.52.60.8-1.0-0.8-3.4-3.2-0.8-3.71.7-0.52.2-3.4-0.9-2.90.1
Light reinforcement 12.44.56.8-2.3-2.32.62.31.72.32.41.6-2.3-1.2-2.32.22.32.01.4
Light reinforcement 23.54.78.0-2.5-1.52.61.62.62.81.42.7-2.0-0.5-2.32.81.62.51.2
Reaction time number correct0.71.03.4-0.31.1-1.2-1.01.20.5-0.81.40.31.20.10.8-1.00.6-1.8
Reaction time mean minus median1.62.15.21.60.9-1.0-0.9-1.9-2.2-0.8-2.31.20.51.5-2.2-0.8-1.70.3
Reaction time mean minus median AUC0.50.61.60.90.4-0.0-0.3-1.2-1.1-0.3-1.30.6-0.20.8-1.2-0.3-1.00.8
Reaction time num false alarms0.10.20.90.2-0.40.90.4-0.40.2-0.0-0.10.2-0.90.10.00.3-0.3-0.3
Reaction time num false alarms AUC0.30.41.7-0.0-0.71.30.8-0.20.60.20.1-0.1-1.2-0.20.30.7-0.10.4
Reaction time trials correct on left0.71.03.4-0.31.1-1.2-1.01.20.5-0.81.40.31.20.10.8-1.00.6-1.8
Reaction time trials on left0.71.03.2-0.31.0-1.2-0.91.20.6-0.71.40.21.2-0.00.9-0.90.7-1.8
Reaction time mean1.31.84.21.70.6-0.5-0.6-1.9-1.9-1.3-2.01.20.11.4-1.9-0.5-1.7-0.0
Reaction time mean AUC1.82.45.01.90.9-0.9-0.9-2.1-2.2-1.5-2.21.50.31.7-2.2-0.8-1.9-0.0
Median of all reaction times0.81.02.41.30.3-0.1-0.3-1.5-1.4-1.2-1.50.90.01.0-1.5-0.2-1.3-0.2
Reaction time omissions0.20.20.6-0.2-0.7-0.30.8-0.1-0.30.4-0.5-0.50.7-0.3-0.20.70.20.1
Reaction time false alarm rate0.60.83.2-0.1-1.11.81.2-0.50.50.7-0.3-0.4-1.6-0.40.11.1-0.21.1
Reaction time premature initiation rate0.71.05.5-1.0-0.00.20.01.60.4-0.21.1-0.82.3-0.80.80.11.40.8
Reaction time premature initiations1.11.68.1-1.10.5-0.4-0.52.10.7-0.61.8-0.62.9-0.71.2-0.51.6-0.3
Std. dev. reaction times1.31.84.01.50.9-1.0-0.9-1.7-2.0-1.1-1.91.20.71.4-2.0-0.8-1.6-0.3
Reaction time trials completed0.71.03.2-0.31.0-1.2-0.91.20.6-0.71.40.21.2-0.00.9-0.90.7-1.8
Reaction time trials AUC0.71.03.2-0.31.0-1.2-1.01.20.6-0.81.40.31.10.10.8-1.00.6-1.8
Social response proportion1.21.34.7-0.80.4-0.0-0.41.70.9-0.92.2-0.32.0-0.51.3-0.31.3-0.8
Social responses0.70.92.0-0.9-0.70.80.61.20.8-0.11.3-0.81.4-0.91.00.91.20.8
Social time0.40.52.40.5-0.50.50.5-0.9-0.6-0.2-1.00.1-0.00.2-0.70.7-0.51.5
Conditioned locomotion0.30.30.9-0.6-0.20.80.10.90.6-0.21.0-0.40.3-0.50.70.20.80.3
Cocaine response after cond. corrected1.01.13.1-0.40.9-1.0-0.91.30.5-1.01.50.11.7-0.10.8-0.90.8-1.8
Cocaine response after cond. not corrected0.30.41.3-0.40.4-0.4-0.40.90.5-0.41.1-0.00.6-0.20.7-0.40.5-1.2
Cocaine response before conditioning1.21.44.80.1-1.41.61.4-1.20.01.6-1.3-0.5-2.2-0.3-0.41.4-0.61.3
Saline control response0.20.31.6-0.4-0.3-0.20.4-0.10.11.3-0.5-0.6-0.7-0.4-0.00.30.10.7
Condit. Reinf. active minus inactive responses0.30.40.8-0.7-0.80.40.80.40.40.80.2-0.90.5-0.80.40.80.7-0.3
Condit. Reinf. active-inactive response ratio0.10.10.3-0.4-0.30.40.30.20.50.40.4-0.3-0.3-0.40.40.30.30.2
Condit. Reinf. active responses0.50.71.6-0.9-1.20.61.20.40.71.30.3-1.1-0.2-1.00.61.20.8-0.2
Condit. Reinf. inactive responses0.70.82.5-0.9-1.20.71.20.30.61.6-0.0-1.2-0.5-1.00.51.20.7-0.3
Condit. Reinf. lever presses0.71.02.60.6-1.00.91.0-1.6-0.60.7-1.6-0.1-1.60.1-1.01.0-0.91.0
Condit. Reinf. lever reinforcers received0.50.71.8-0.8-1.20.71.30.20.61.30.0-1.0-0.6-0.90.51.20.60.3
Pavlov. Cond. lever latency0.81.23.6-1.20.1-0.4-0.21.91.20.21.8-0.71.2-0.91.4-0.11.4-1.0
Pavlov. Cond. magazine entry latency1.31.56.21.1-0.30.60.3-1.9-0.70.0-1.70.7-2.50.8-1.20.3-1.51.6
Pavlov. Cond. change in total contacts1.82.53.92.01.2-1.2-1.2-2.0-1.9-1.8-1.71.70.01.8-1.9-1.2-1.9-0.6
Pavlov. Cond. index score1.62.15.71.70.3-0.1-0.3-2.4-1.6-0.7-2.21.2-1.71.4-1.9-0.3-2.01.0
Pavlov. Cond. latency score1.72.15.81.70.20.1-0.2-2.4-1.6-0.7-2.31.1-1.61.3-1.9-0.2-2.01.2
Pavlov. Cond. lever contacts1.52.16.31.70.2-0.2-0.2-2.5-1.7-0.4-2.41.2-1.41.4-2.0-0.2-2.00.4
Pavlov. Cond. magazine entry number0.91.15.4-0.80.5-0.7-0.51.50.4-0.11.3-0.42.3-0.50.8-0.51.1-1.7
Pavlov. Cond. intertrial magazine entries3.44.47.8-2.3-2.52.22.51.52.32.81.3-2.4-1.4-2.42.02.51.90.1
Pavlov. Cond. lever-magazine prob. diff.1.41.95.01.60.3-0.0-0.3-2.2-1.4-0.7-2.01.2-1.61.3-1.7-0.3-1.91.0
Pavlov. Cond. response bias1.92.77.61.90.4-0.5-0.4-2.8-1.7-0.5-2.51.4-1.91.6-2.1-0.4-2.30.4
Conditioned reinforcement - actives1.21.13.6-1.1-0.30.90.31.61.50.41.9-0.70.4-1.01.60.41.3-0.1
Conditioned reinforcement - inactives1.41.65.4-0.8-1.61.71.60.00.71.5-0.1-1.1-1.3-1.00.51.60.52.3
Conditioned locomotion0.10.21.00.3-0.20.70.2-0.50.1-0.1-0.20.3-1.00.2-0.10.2-0.4-0.1
Intermittent access intake day 1-15 change2.02.03.6-1.5-1.71.41.60.81.01.70.4-1.8-0.3-1.61.01.81.31.9
Intermittent access intake escalation1.61.62.7-1.5-1.41.01.31.01.01.60.6-1.6-0.2-1.51.01.51.31.4
Intermittent access intake escalation 20.60.61.1-0.9-0.90.60.90.70.60.50.5-1.00.3-0.90.71.00.90.3
Intermitt. access day 1 inactive lever presses0.70.71.6-1.1-0.90.20.90.80.31.20.2-1.30.9-1.00.50.91.1-0.0
Intermitt. access day 15 inactive lever presses0.30.41.0-0.5-0.90.40.9-0.10.11.0-0.4-0.8-0.2-0.6-0.01.00.40.6
Intermitt. access escalation Index0.50.51.30.51.1-1.0-1.1-0.2-0.4-0.5-0.10.70.10.7-0.4-1.1-0.5-0.6
Intermittent access day 1 total infusions0.70.84.0-0.8-0.70.60.80.21.02.00.2-0.8-1.6-0.80.70.60.40.6
Intermittent access day 15 total infusions1.72.05.4-1.6-1.41.31.51.01.32.30.6-1.7-0.7-1.61.21.31.31.4
Intermittent access terminal intake (last 3 days)1.11.23.1-1.2-1.01.11.00.91.21.80.7-1.2-0.8-1.21.10.81.01.1
Intermittent access total infusions1.82.06.3-1.5-1.31.31.41.01.52.50.8-1.6-1.2-1.51.31.21.31.3
Intermittent access day 1 locomotion1.31.45.1-1.0-1.41.11.50.10.92.3-0.1-1.3-1.5-1.10.61.30.60.8
Intermittent access day 15 total locomotion1.41.53.0-1.4-1.21.11.21.11.41.71.0-1.4-0.5-1.41.31.21.20.8
Intermittent access total locomotion1.11.24.4-1.0-1.31.01.40.31.02.10.1-1.2-1.3-1.10.71.20.70.5
Intermittent access standard deviation0.30.32.0-0.7-0.2-0.20.20.40.31.40.1-0.7-0.1-0.50.40.30.5-0.1
Cocaine induced anxiety3.13.56.72.31.2-1.3-1.2-2.4-2.6-1.7-2.51.80.42.1-2.6-1.4-2.2-0.0
Post-drug Anxiety0.30.41.2-0.0-0.80.50.8-0.2-0.6-0.1-0.6-0.51.1-0.3-0.50.70.21.0
Baseline Anxiety2.72.84.1-2.0-1.71.51.71.61.82.01.3-2.0-0.4-2.01.72.01.80.6
Lifetime Intake1.31.54.9-1.2-1.11.11.20.71.32.20.5-1.3-1.4-1.21.10.90.91.2
Incentive Sensitization - Responses2.22.23.8-1.4-1.61.91.51.02.01.51.3-1.3-1.6-1.51.71.41.20.9
Incentive Sensitization - Breakpoint2.62.64.0-1.5-1.82.01.81.02.01.71.3-1.5-1.7-1.61.71.61.31.2
Progressive ratio test 1 active lever presses0.80.92.1-1.1-0.30.30.31.21.41.51.2-0.8-0.6-0.91.30.31.0-0.2
Progressive ratio test 1 breakpoint1.11.22.5-1.3-0.40.50.41.41.61.51.5-1.0-0.4-1.11.50.41.2-0.2
Progressive ratio test 1 inactive lever presses3.63.89.1-2.5-1.81.01.82.01.93.01.4-2.5-0.1-2.32.01.82.30.7
Progressive ratio test 2 active lever presses2.83.06.2-2.0-1.21.31.22.02.52.12.2-1.6-1.1-1.82.41.01.90.1
Progressive ratio test 2 breakpoint2.72.95.6-1.9-1.51.41.41.72.42.31.8-1.7-1.4-1.82.21.21.70.5
Progressive ratio test 2 inactive lever presses1.21.44.0-1.3-1.30.81.30.81.22.00.6-1.4-1.1-1.31.11.11.00.7
Total sessions with >9 infusions0.50.61.1-0.7-0.91.10.90.60.90.80.6-0.7-0.5-0.80.80.70.70.7
Short access day 1 total inactive lever presses1.61.88.0-1.2-1.40.71.40.21.22.8-0.0-1.3-2.3-1.20.81.40.60.9
Short access day 10 total inactive lever presses0.80.91.6-1.2-1.10.51.00.90.81.20.6-1.30.1-1.20.91.11.10.1
Short access day 1 total infusions0.40.41.0-0.7-0.40.40.40.70.91.00.7-0.6-0.5-0.60.80.30.6-0.0
Short access day 10 total infusions0.60.63.60.3-0.1-0.30.1-0.9-0.11.3-1.00.1-1.90.3-0.4-0.1-0.71.1
Short access total infusions1.01.13.8-1.0-1.00.91.10.41.11.90.3-1.1-1.5-1.00.80.90.71.1
Short access day 1 locomotion0.50.51.80.90.1-0.3-0.1-1.2-1.0-0.2-1.30.5-0.40.7-1.1-0.2-1.00.2
Short access day 10 total locomotion0.40.51.60.4-0.90.70.8-1.0-0.20.4-0.90.0-1.30.1-0.50.8-0.60.4
Short access total locomotion0.70.71.9-0.1-1.41.01.3-0.6-0.01.1-0.9-0.7-0.9-0.5-0.31.3-0.10.8
Compulsive drug intake0.50.51.60.70.1-0.4-0.1-1.1-0.80.2-1.30.3-0.60.5-1.0-0.4-0.80.9
One hour access (0.3 mA shock)0.30.31.9-0.5-0.20.10.20.30.51.40.1-0.5-0.9-0.40.4-0.10.30.6
One hour access (shock baseline)0.20.20.5-0.40.4-0.2-0.40.70.60.50.7-0.0-0.1-0.10.6-0.50.4-0.7
Number of responses in last shaping day0.10.10.30.50.4-0.3-0.4-0.4-0.3-0.5-0.20.5-0.10.5-0.3-0.3-0.50.0
Context. condit. distance diff. score4.65.69.8-2.7-1.52.61.52.83.11.73.1-2.1-0.9-2.43.11.52.62.4
Locomotion velocity, session 11.81.92.61.61.4-1.4-1.4-1.3-1.5-1.5-1.01.60.61.6-1.4-1.4-1.4-1.2
Locomotion distance, session 10.81.02.31.20.5-1.0-0.5-1.5-1.1-0.2-1.21.0-0.81.1-1.2-0.5-1.4-0.7
Locomotion velocity, session 20.80.94.60.90.3-0.8-0.4-1.1-1.0-0.2-1.00.70.20.8-1.1-0.4-1.0-2.2
Locomotion distance, session 22.43.56.72.11.1-1.8-1.1-2.6-1.9-0.4-2.41.8-1.41.9-2.2-1.1-2.4-2.4
Locomotion velocity, session 30.30.41.0-0.7-0.30.30.30.90.90.21.0-0.5-0.0-0.60.90.30.7-0.8
Locomotion distance, session 31.11.22.2-1.3-0.81.00.81.31.51.01.4-1.0-0.7-1.21.40.81.20.5
Stereotopy head waving bouts, day 31.01.25.20.71.0-1.4-1.0-0.2-1.0-1.2-0.30.81.80.8-0.7-1.0-0.4-2.3
Stereotopy head waving duration, day 31.61.93.11.41.4-1.6-1.4-1.1-1.5-1.4-1.11.40.81.5-1.4-1.4-1.3-1.8
Locomotion velocity, session 79.310.217.3-3.7-2.62.82.73.74.22.93.7-3.3-1.0-3.64.12.73.61.4
Locomotion distance, session 75.36.712.8-3.1-2.02.22.03.13.62.23.2-2.5-1.2-2.93.52.02.90.5
Stereotopy head waving bouts, day 70.70.81.51.00.5-1.1-0.4-1.1-1.2-0.3-1.20.70.60.9-1.2-0.4-1.0-0.8
Stereotopy head waving duration, day 70.81.02.11.00.8-1.1-0.8-0.9-1.4-0.8-1.00.81.41.0-1.2-0.8-0.8-0.8
Locomotion velocity, session 80.40.41.0-0.7-0.40.10.30.71.00.80.7-0.5-0.7-0.60.90.30.60.7
Locomotion distance, session 80.81.25.3-0.8-1.01.20.90.21.41.60.6-0.7-2.3-0.81.00.90.40.2
Degree of sensitization distance1.92.03.9-1.7-1.00.71.01.82.01.11.9-1.4-0.2-1.62.01.01.7-0.1
Degree of sensitization stereotypy0.20.20.60.40.1-0.6-0.1-0.5-0.70.2-0.70.10.50.3-0.6-0.1-0.4-0.1
Condit. Reinf. active minus inactive responses0.40.51.50.5-0.2-0.40.3-0.8-1.20.1-1.2-0.11.00.2-1.10.2-0.40.5
Condit. Reinf. active-inactive response ratio0.40.53.20.50.6-0.6-0.4-0.0-0.8-1.1-0.10.41.80.4-0.5-0.5-0.10.2
Condit. Reinf. active responses0.50.62.00.1-1.00.11.0-1.0-0.81.1-1.4-0.60.2-0.2-0.91.0-0.30.7
Condit. Reinf. inactive responses1.21.44.5-0.2-1.60.91.4-1.1-0.22.1-1.5-0.9-1.8-0.5-0.61.5-0.41.0
Incentive salience index mean1.01.23.30.2-1.30.61.4-1.3-1.11.1-1.8-0.70.1-0.3-1.21.3-0.41.7
Condit. Reinf. lever presses2.02.68.3-0.3-2.21.52.2-1.3-0.52.1-1.9-1.4-1.1-0.9-0.92.2-0.12.9
Time in familiar zone, hab. session 11.41.36.8-0.9-1.01.31.00.41.11.00.7-0.9-1.3-0.90.91.00.62.6
Time in novel zone, hab. session 13.43.315.90.82.0-2.4-2.00.4-0.9-1.70.41.32.61.2-0.4-2.0-0.3-4.0
Total zone transitions, hab. session 10.81.12.21.20.8-1.3-0.8-1.2-1.0-0.6-1.01.1-0.11.1-1.1-0.8-1.2-1.5
Total locomotion distance, hab. session 10.91.33.11.30.3-1.1-0.3-1.7-1.4-0.3-1.50.9-0.01.1-1.5-0.3-1.4-1.8
Locomotion velocity, hab. session 11.31.95.61.60.2-0.8-0.2-2.4-1.7-0.1-2.31.0-1.11.3-2.0-0.2-1.9-0.4
Time in familiar zone, hab. session 20.40.41.00.01.0-0.1-1.00.70.3-0.90.80.5-0.00.30.4-1.00.1-0.9
Time in novel zone, hab. session 20.10.10.60.3-0.0-0.70.0-0.6-0.40.3-0.50.20.40.2-0.40.0-0.3-0.0
Total zone transitions, hab. session 22.43.15.02.01.5-1.8-1.5-2.0-2.2-1.2-2.11.80.32.0-2.2-1.5-2.0-1.4
Total locomotion distance, hab. session 21.41.83.11.51.0-1.5-1.0-1.7-1.7-0.6-1.61.20.41.4-1.8-1.0-1.5-1.4
Locomotion velocity, hab. session 22.12.84.61.91.3-1.7-1.3-2.1-2.1-0.8-2.01.60.11.8-2.1-1.3-2.0-1.7
Novel to familiar place preference ratio0.40.52.4-0.4-0.7-0.60.7-0.20.11.6-0.4-0.6-0.0-0.5-0.00.70.2-1.3
Novelty place preference0.40.42.6-0.5-0.7-0.40.7-0.20.11.6-0.4-0.7-0.1-0.50.00.70.2-1.0
Time in novel zone, NPP test0.30.42.0-0.3-0.5-0.50.5-0.20.11.4-0.4-0.5-0.0-0.4-0.00.50.1-1.2
Total zone transitions, NPP test0.40.61.60.80.2-0.6-0.2-1.2-0.90.3-1.30.5-0.50.7-1.0-0.2-1.0-1.1
Total locomotion distance, NPP test0.30.51.40.4-0.5-0.10.5-1.1-0.51.0-1.2-0.0-0.90.2-0.80.5-0.7-0.5
Locomotion velocity, NPP test0.30.51.70.1-0.7-0.00.7-0.9-0.41.3-1.1-0.3-0.9-0.1-0.60.7-0.4-0.2
Pavlov. Cond. lever latency1.41.87.50.81.6-1.4-1.80.2-0.2-1.90.71.40.71.1-0.0-1.7-0.5-2.7
Pavlov. Cond. magazine entry latency0.70.91.7-1.0-1.11.31.20.50.71.20.3-1.2-0.4-1.10.61.20.91.0
Pavlov. Cond. change in total contacts0.30.31.5-0.2-0.60.10.8-0.5-0.31.2-0.9-0.6-0.2-0.3-0.40.7-0.0-0.2
Pavlov. Cond. index score1.21.64.5-0.9-1.51.61.7-0.10.31.8-0.5-1.4-0.9-1.10.21.60.62.1
Pavlov. Cond. latency score1.62.15.8-1.1-1.91.71.9-0.00.52.1-0.5-1.7-0.9-1.30.31.90.72.4
Pavlov. Cond. lever contacts1.51.87.6-0.8-1.61.51.7-0.20.21.9-0.7-1.4-0.8-1.10.01.60.52.8
Pavlov. Cond. magazine entry number0.20.20.60.40.5-0.6-0.5-0.1-0.3-0.8-0.00.50.60.4-0.2-0.5-0.30.1
Pavlov. Cond. intertrial magazine entries0.50.63.10.2-0.90.30.8-0.9-0.60.5-1.2-0.3-0.4-0.1-0.80.8-0.41.7
Pavlov. Cond. lever-magazine prob. diff.0.91.23.2-0.6-1.31.41.4-0.30.21.6-0.6-1.1-1.1-0.90.01.30.31.8
Pavlov. Cond. response bias0.40.51.7-0.5-0.81.11.00.00.10.9-0.3-0.8-0.5-0.60.10.90.41.3
Bone: apparent density0.20.43.70.3-0.20.20.3-0.80.20.5-0.60.2-1.90.2-0.10.2-0.6-0.2
Bone surface0.40.63.60.70.00.10.1-1.2-0.30.3-1.00.6-1.90.6-0.6-0.0-1.1-0.7
Bone volume0.40.75.40.80.2-0.1-0.2-1.2-0.10.3-0.90.8-2.30.7-0.5-0.2-1.2-0.5
Bone: connectivity density0.40.61.3-0.6-1.01.21.10.20.41.0-0.2-0.9-0.7-0.80.31.00.50.7
Bone: cortical apparent density1.11.54.4-1.4-0.1-0.10.02.11.0-0.11.9-1.01.9-1.11.50.11.80.1
Bone: cortical area0.20.31.70.30.0-0.0-0.0-0.60.20.1-0.10.4-1.30.3-0.0-0.0-0.5-1.2
Bone: cortical porosity1.01.13.50.9-0.40.80.4-1.7-1.00.3-1.90.3-1.50.6-1.30.4-1.21.4
Bone: cortical porosity1.11.23.50.9-0.30.80.3-1.7-0.90.2-1.70.5-1.90.6-1.20.3-1.31.3
Bone: cortical thickness0.20.30.8-0.5-0.50.40.60.30.60.90.2-0.6-0.5-0.60.50.50.4-0.3
Bone: cortical thickness0.60.71.6-1.0-0.4-0.00.41.21.20.91.3-0.70.1-0.91.20.41.0-0.4
Bone: cortical tissue density1.21.54.6-1.4-0.1-0.1-0.02.11.0-0.22.0-0.92.0-1.11.50.01.80.1
Bone: elastic displacement0.70.71.60.80.6-1.3-0.5-0.9-1.3-0.1-1.30.60.50.8-1.2-0.6-0.8-0.7
Bone: elastic work1.52.04.91.60.7-1.3-0.7-2.1-1.6-0.1-2.21.3-1.21.5-1.9-0.7-1.9-0.1
Bone: endosteal estimation0.40.82.31.10.4-0.5-0.5-1.2-0.4-0.8-0.61.2-1.51.0-0.7-0.4-1.3-0.8
Bone: endosteal perimeter0.51.02.31.30.5-0.5-0.6-1.4-0.8-1.2-0.71.3-0.71.1-0.9-0.5-1.4-1.5
Bone: final force0.50.82.7-0.5-1.10.61.0-0.10.71.2-0.2-0.6-1.6-0.60.41.00.11.5
Bone: final moment0.30.62.4-0.1-0.90.30.8-0.50.20.9-0.6-0.4-1.5-0.3-0.00.9-0.21.4
Bone: marrow area0.40.82.61.10.3-0.4-0.4-1.2-0.4-0.7-0.61.1-1.61.0-0.7-0.3-1.3-0.7
Bone: maximum diameter0.30.66.10.40.4-0.3-0.5-0.20.3-0.70.50.8-0.50.50.2-0.5-0.4-2.5
Bone: maximum force0.30.54.00.4-0.3-0.20.2-0.9-0.00.5-0.80.3-2.00.3-0.40.2-0.8-0.0
Bone: maximum moment0.40.73.60.7-0.2-0.50.1-1.3-0.40.3-1.20.5-1.90.6-0.70.2-1.1-0.0
Bone: minimum diameter0.50.92.61.00.1-0.4-0.3-1.5-0.5-0.2-0.90.9-1.50.9-0.9-0.1-1.3-1.6
Bone: periosteal estimation0.30.62.30.80.2-0.2-0.3-0.9-0.1-0.5-0.30.9-1.50.7-0.3-0.2-1.0-1.2
Bone: periosteal perimeter0.20.43.60.50.1-0.3-0.2-0.60.0-0.40.00.6-0.70.5-0.1-0.2-0.6-1.9
Bone: post-yield work0.91.22.7-1.1-0.90.80.90.81.61.11.3-0.8-1.6-1.01.40.90.80.6
Bone: stiffness0.30.42.6-0.2-0.80.80.7-0.30.50.8-0.2-0.3-1.6-0.30.20.8-0.10.3
Bone: tissue strength0.20.20.70.4-0.4-0.00.4-0.8-0.40.0-0.80.2-0.50.2-0.60.4-0.6-0.5
Bone: trabecular number0.40.62.3-0.4-0.91.21.0-0.20.61.0-0.2-0.5-1.5-0.50.40.90.10.6
Bone: trabecular spacing0.60.81.80.71.0-1.1-1.1-0.2-0.9-1.4-0.20.91.30.8-0.6-1.0-0.5-1.1
Bone: trabecular thickness0.60.75.3-0.3-0.60.50.7-0.40.61.3-0.4-0.4-2.3-0.30.30.6-0.20.9
Bone: trabecular tissue density0.71.02.11.01.3-0.7-1.3-0.5-0.8-1.4-0.31.20.31.1-0.7-1.2-0.9-1.4
Breakpoint value in progressive ratio session0.80.93.80.21.4-2.0-1.40.4-0.4-0.00.10.50.80.6-0.2-1.6-0.1-1.1
Distance traveled before self-admin2.72.93.92.01.8-1.9-1.8-1.6-1.8-1.7-1.52.00.02.0-1.8-1.7-1.9-1.0
Distance traveled after self-admin1.21.33.90.91.7-1.0-1.70.1-0.3-2.00.61.40.71.1-0.1-1.7-0.5-1.1
Delta time in closed arm before/after self-admin0.30.31.00.3-0.41.00.5-0.5-0.0-0.4-0.20.2-0.80.1-0.20.4-0.40.8
Delta time in open arm before/after self-admin0.10.10.2-0.3-0.40.00.30.20.40.30.2-0.3-0.3-0.30.30.40.2-0.3
Diff in mean of infusions in LGA sessions1.21.45.2-0.01.6-2.3-1.70.8-0.4-0.10.40.41.80.5-0.0-1.70.2-1.5
Extinction: sum of active levers before priming0.60.62.1-0.9-0.60.30.60.60.91.50.5-0.9-0.9-0.90.80.40.70.7
Active lever presses in extinction session 60.90.81.5-1.2-0.70.50.81.11.01.20.9-1.10.0-1.11.10.51.10.5
Delta distance traveled before/after self-admin1.01.04.2-0.80.50.2-0.51.71.2-0.52.0-0.21.1-0.51.4-0.61.2-0.7
Delta ambulatory time before/after self-admin0.50.52.1-0.60.40.2-0.41.20.8-0.31.4-0.10.8-0.31.0-0.50.8-0.5
Time in closed arm before self-admin0.00.00.20.0-0.20.30.1-0.00.2-0.40.20.0-0.1-0.10.20.30.00.2
Time in closed arm after self-admin0.10.10.50.40.20.1-0.2-0.2-0.3-0.7-0.20.30.20.3-0.3-0.1-0.30.1
Time in open arm before self-admin0.40.51.40.51.1-0.5-1.1-0.1-0.4-0.50.00.70.50.7-0.3-1.2-0.4-1.0
Time in open arm after self-admin0.00.10.20.20.2-0.2-0.2-0.10.0-0.30.10.3-0.30.20.0-0.4-0.2-0.2
Sum of active levers in priming session hrs 5-61.00.93.7-0.70.7-0.2-0.61.61.0-0.61.9-0.01.2-0.31.3-0.81.0-0.5
Time to tail flick, vehicle, before self-admin1.71.76.1-1.5-1.40.91.50.81.12.50.3-1.7-0.7-1.51.01.31.20.9
Time to tail flick, vehicle, after self-admin1.01.12.9-0.90.8-0.9-0.91.70.60.21.4-0.41.7-0.41.0-0.71.2-1.2
Time to tail flick, test, before self-admin0.50.53.30.5-0.40.40.5-1.1-0.10.2-0.80.3-1.80.3-0.40.3-0.80.4
Time to tail flick, test, after self-admin3.03.14.9-1.8-2.22.12.21.41.71.61.3-2.0-0.1-2.01.72.21.81.2
Delta time to tail flick, vehicle, before/after SA0.80.82.2-0.41.0-1.2-1.01.20.3-0.41.10.11.50.00.6-0.80.6-1.1
Delta time to tail flick, test, before/after SA2.52.33.7-1.7-1.21.41.31.91.70.81.9-1.50.9-1.71.81.31.90.6
Ambulatory time before self-admin1.61.72.51.41.4-1.6-1.4-1.3-1.2-0.8-1.21.4-0.71.4-1.2-1.3-1.5-1.2
Ambulatory time after self-admin1.92.14.21.32.0-1.6-2.0-0.5-1.0-2.0-0.21.70.61.5-0.8-2.0-1.1-1.2
Total heroin consumption0.91.12.40.81.5-1.4-1.5-0.5-0.9-0.5-0.61.00.21.1-0.8-1.6-0.8-1.1
Area under the delay curve0.50.52.20.7-0.10.10.1-1.3-0.40.1-1.00.5-1.50.5-0.60.1-1.00.1
Delay disc. indifference point, 0s delay0.91.02.41.20.2-0.3-0.3-1.6-1.4-0.8-1.60.80.11.0-1.5-0.2-1.20.1
Delay disc. indifference point, 16s delay0.40.41.40.60.3-0.3-0.3-1.0-0.40.1-0.80.6-1.20.6-0.6-0.3-0.80.3
Delay disc. indifference point, 2s delay1.71.93.81.81.0-0.8-1.0-1.8-1.5-2.0-1.21.70.11.6-1.5-1.0-1.7-0.2
Delay disc. indifference point, 24s delay0.10.10.50.20.2-0.1-0.1-0.20.2-0.10.10.3-0.70.20.1-0.2-0.20.1
Delay disc. indifference point, 4s delay0.40.50.80.90.6-0.2-0.6-0.8-0.6-0.8-0.50.9-0.00.8-0.6-0.6-0.8-0.4
Delay disc. indifference point, 8s delay0.40.42.0-0.2-0.70.60.6-0.40.30.9-0.4-0.3-1.4-0.30.10.7-0.10.6
Delay discount exponential model param0.50.52.4-0.70.1-0.2-0.11.20.3-0.10.9-0.61.5-0.50.6-0.11.0-0.1
Delay discount hyperbolic model param0.70.72.2-1.1-0.30.10.21.50.60.41.1-0.91.3-0.90.90.31.20.1
Fecal boli incidents, locomotor time 11.01.13.01.00.9-0.9-0.9-1.3-0.70.3-1.31.0-1.71.1-1.0-0.9-1.3-0.9
Change in fecal boli incidents, locomotor task0.70.65.80.10.2-0.6-0.20.5-0.5-1.20.40.12.40.1-0.1-0.30.4-0.9
Time >=10cm from walls, locomotor time 10.20.20.7-0.0-0.70.60.6-0.3-0.30.3-0.8-0.4-0.6-0.2-0.40.7-0.10.5
Bouts of movement, locomotor time 10.30.31.20.00.8-0.2-0.80.7-0.2-0.80.50.31.10.20.1-0.90.3-0.2
Total resting periods, locomotor time 10.40.51.50.00.9-0.4-1.00.8-0.1-0.90.70.31.20.30.2-1.00.3-0.6
Rest time, locomotor task time 11.61.73.61.31.6-1.1-1.8-0.5-1.0-1.8-0.41.60.11.5-0.9-1.9-1.2-1.2
Distance moved, locomotor task time 11.41.52.9-1.3-1.51.01.71.00.91.20.7-1.60.7-1.51.01.71.30.7
Vertical activity count, locomotor time 10.30.40.70.60.6-0.8-0.4-0.5-0.9-0.6-0.70.50.80.6-0.8-0.5-0.5-0.0
Time >=10cm from walls, locomotor time 21.41.42.21.31.4-1.2-1.4-0.8-1.4-1.5-0.91.40.81.4-1.2-1.3-1.1-0.6
Bouts of movement, locomotor time 20.70.73.0-0.01.3-0.7-1.40.6-0.0-0.40.70.51.00.40.2-1.30.2-1.7
Total resting periods, locomotor time 20.60.62.5-0.01.3-0.7-1.30.60.1-0.30.60.40.60.40.3-1.20.1-1.6
Rest time, locomotor task time 20.30.41.00.01.0-0.7-0.90.50.4-0.10.40.5-0.90.40.4-1.0-0.1-0.8
Distance moved, locomotor task time 20.30.41.4-0.3-1.00.41.2-0.2-0.10.6-0.5-0.70.4-0.6-0.21.10.20.5
Vertical activity count, locomotor time 21.41.62.11.41.3-1.2-1.1-1.2-1.4-1.4-1.11.40.41.5-1.4-1.2-1.4-0.7
Weight adjusted by age1.31.43.41.20.8-1.1-0.9-0.8-1.7-1.8-1.01.11.81.2-1.4-0.8-1.0-0.1
Seeking ratio, delayed vs. immediate footshock0.40.43.20.0-0.7-0.10.6-0.1-0.7-0.6-0.3-0.41.8-0.2-0.50.70.30.8
Locomotion in novel chamber0.60.84.50.70.20.1-0.3-1.3-0.40.5-1.20.6-2.10.7-0.8-0.1-1.20.1
Locomotion in novel chamber post-restriction0.10.10.30.20.3-0.3-0.4-0.10.3-0.40.30.5-0.60.30.2-0.3-0.20.3
Progressive ratio0.50.61.6-0.80.5-0.5-0.51.31.00.41.3-0.3-0.1-0.41.1-0.60.8-1.2
Food seeking constrained by brief footshock2.93.58.9-0.42.5-1.7-2.62.20.4-1.42.00.72.70.41.0-2.60.9-3.0
Seeking ratio, punishment vs. effort0.30.31.90.40.5-0.0-0.5-0.0-0.5-1.2-0.00.51.40.5-0.3-0.4-0.2-0.2
Run reversals in cocaine runway, females0.50.51.7-0.4-0.60.90.60.31.10.30.8-0.3-1.3-0.50.80.60.30.7
Run reversals in cocaine runway, males1.21.22.50.91.0-1.5-1.0-1.2-0.70.1-1.21.0-1.61.1-0.9-1.1-1.3-0.7
Latency to leave start box in cocaine runway1.51.62.91.21.4-1.7-1.5-0.7-1.4-1.5-0.61.31.31.3-1.1-1.4-1.0-1.1
Latency to leave start box in cocaine runway, F0.91.02.70.81.1-1.6-1.2-0.5-1.1-0.9-0.60.91.21.0-0.9-1.1-0.7-0.8
Latency to leave start box in cocaine runway, M0.10.10.30.50.3-0.2-0.3-0.5-0.3-0.4-0.20.5-0.50.4-0.4-0.2-0.50.0
Cd content in liver0.40.40.7-0.8-0.40.20.40.80.60.70.8-0.70.6-0.70.70.40.80.3
Co content in liver1.41.64.20.62.0-1.3-2.00.60.2-1.71.21.40.71.00.4-2.1-0.2-1.0
Cu content in liver1.21.54.60.81.4-2.0-1.3-0.1-0.8-1.10.31.01.60.9-0.5-1.5-0.4-2.2
Fe content in liver0.40.41.1-0.7-1.00.40.80.40.50.50.5-0.80.4-0.80.51.00.7-0.4
K content in liver1.01.01.6-1.0-1.21.31.30.71.20.90.5-1.1-0.9-1.11.01.20.90.7
Mg content in liver0.30.30.7-0.4-0.30.40.40.50.90.20.6-0.2-0.8-0.40.80.30.4-0.8
Mn content in liver0.20.21.3-0.2-0.10.60.20.30.8-0.10.50.0-1.1-0.20.60.10.10.3
Na content in liver3.84.011.02.50.7-0.7-0.7-3.1-2.6-1.2-3.31.8-0.92.1-2.8-0.7-2.7-0.3
Rb content in liver0.60.71.5-1.1-0.60.20.71.20.70.60.9-1.11.1-1.00.90.61.2-0.1
Se content in liver2.73.35.82.21.2-1.7-1.2-2.2-2.4-1.7-2.31.80.72.0-2.4-1.2-2.1-0.9
Sr content in liver0.30.30.50.60.4-0.6-0.5-0.6-0.5-0.5-0.40.70.10.6-0.5-0.3-0.6-0.4
Zn content in liver2.22.44.91.91.0-0.9-0.9-2.2-2.0-1.0-2.21.5-0.31.7-2.1-1.0-2.00.1