Hub : Genes

Esco2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000015921 0.02 0.02 4.3e-03 0.02 0.02 0.02 0.02 1.9e-03 5.2e-03 5.7e-03 3.2e-03
2 BLA gene expression ENSRNOG00000015921 0.05 0.04 8.8e-03 0.02 0.01 0 0 2.3e-02 6.2e-02 1.9e-01 3.2e-01
3 Brain gene expression ENSRNOG00000015921 0.16 0.08 3.1e-15 0.17 0.16 0.16 0.17 2.0e-15 8.5e-15 4.7e-15 2.8e-15
4 Brain mRNA stability ENSRNOG00000015921 0.03 0.02 5.4e-03 0.02 0.02 0.02 0.02 1.1e-02 4.7e-03 4.4e-03 9.2e-03
5 LHb gene expression ENSRNOG00000015921 0.2 0.13 6.7e-03 0.02 0.04 -0 0.02 1.2e-01 5.2e-02 4.2e-01 1.2e-01
6 Liver gene expression ENSRNOG00000015921 0.06 0.04 8.8e-07 0.06 0.06 0.04 0.06 3.7e-07 1.0e-06 9.0e-06 6.0e-07
7 NAcc gene expression ENSRNOG00000015921 0.04 0.03 5.3e-03 0.02 0.03 0.02 0.03 6.3e-03 5.7e-03 1.3e-02 2.0e-03
8 PL gene expression ENSRNOG00000015921 0.1 0.05 1.1e-06 0.07 0.04 0.06 0.06 5.8e-06 2.3e-04 4.2e-05 1.6e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
BMI with tail0.62.02.5-1.4-1.3-1.4-1.2-1.5-1.4-1.6-1.5
BMI without tail0.00.10.3-0.10.4-0.10.5-0.3-0.2-0.2-0.2
Body weight0.10.30.7-0.4-0.9-0.4-0.7-0.3-0.4-0.8-0.3
Epididymis fat weight0.51.21.90.91.41.01.41.11.01.11.0
Glucose1.62.53.1-1.7-1.1-1.8-1.2-1.7-1.6-1.6-1.6
Heart weight0.00.00.1-0.1-0.40.0-0.20.1-0.0-0.4-0.0
Left kidney weight0.82.23.8-1.2-1.9-1.5-1.8-1.0-1.2-1.7-1.2
Right kidney weight0.30.81.61.10.11.00.31.31.10.41.1
Tail length0.72.02.41.51.21.51.51.51.51.01.5
Length with tail0.20.81.41.00.11.00.41.21.00.51.1
Length without tail0.40.92.4-0.6-1.5-0.7-1.5-0.4-0.5-0.8-0.5
Liver weight, left4.57.39.7-2.7-2.9-2.7-3.1-2.5-2.6-2.4-2.6
Liver weight, right2.23.65.0-1.8-2.2-1.8-2.1-1.9-1.8-1.9-1.8
Parametrial fat weight2.34.67.91.92.81.82.61.72.02.12.0
Retroperitoneal fat weight0.10.41.20.31.00.41.10.40.30.60.4
Intraocular pressure1.62.22.61.51.41.51.51.51.61.41.6
Extensor digitorum longus weight6.325.435.8-4.7-6.0-4.6-5.9-4.9-4.5-4.9-4.6
Soleus weight0.51.51.8-1.2-1.2-1.2-1.2-1.3-1.2-1.2-1.2
Tibialis anterior weight4.214.321.6-3.4-4.7-3.3-4.6-3.6-3.4-3.7-3.4
Tibia length1.95.57.02.61.62.51.52.62.62.32.6
Number of licking bursts0.10.10.2-0.50.0-0.50.0-0.4-0.4-0.3-0.4
Food consumed during 24 hour testing period0.20.20.7-0.2-0.8-0.1-0.7-0.2-0.2-0.5-0.2
Times rat made contact with spout0.10.10.2-0.4-0.1-0.5-0.2-0.4-0.3-0.3-0.3
Mean time between licks in bursts3.75.26.82.22.42.22.62.32.22.22.2
Mean num. licks in bursts0.00.00.00.1-0.20.1-0.20.00.10.10.1
Std. dev. time between licks in bursts8.910.611.63.42.93.23.13.33.43.33.4
Water consumed over 24 hours0.50.61.4-0.5-1.2-0.5-0.9-0.6-0.5-1.0-0.5
Indifference point 0 sec4.97.910.03.22.02.92.23.03.12.83.1
Indifference point AUC4.14.86.3-2.4-1.7-2.5-2.0-2.5-2.2-2.0-2.2
Indifference point function ln k1.31.82.61.50.71.61.01.61.41.21.4
Indifference point function log k1.31.82.61.50.71.61.01.61.41.21.4
Delay discounting total patch changes 0 sec4.06.58.52.91.72.71.92.72.82.52.9
Delay discounting total patch changes 12 sec0.50.71.10.90.70.70.50.71.00.91.0
Delay discounting total patch changes 18 sec0.10.10.20.40.30.20.40.20.40.10.4
Delay discounting total patch changes 24 sec0.70.91.51.20.50.80.40.91.21.11.2
Delay discounting total patch changes 6 sec0.10.20.30.40.50.40.30.40.50.60.5
Delay discounting time to switch 0 sec1.21.82.31.21.51.41.31.31.31.31.3
Delay discounting water rate 0 sec0.10.20.6-0.2-0.8-0.3-0.6-0.4-0.4-0.3-0.4
Delay discounting water rate 12 sec0.10.10.40.0-0.60.3-0.40.0-0.0-0.3-0.0
Delay discounting water rate 18 sec3.34.35.9-2.0-2.4-1.8-2.4-2.0-2.1-1.9-2.0
Delay discounting water rate 24 sec1.01.31.9-1.1-1.2-0.9-0.9-1.1-1.4-1.2-1.4
Delay discounting water rate 6 sec0.71.02.9-0.6-1.7-0.5-1.4-0.7-0.7-1.0-0.7
Locomotor activity0.81.32.31.30.01.3-0.21.31.41.11.5
Locomotor testing distance5.28.610.83.22.23.22.03.13.23.13.3
Locomotor testing rearing8.914.017.54.12.74.22.64.04.13.74.2
Light reinforcement 10.50.91.50.81.20.81.20.80.91.00.9
Light reinforcement 20.70.91.3-1.2-0.3-1.0-0.2-1.0-1.1-1.1-1.0
Reaction time number correct0.10.10.2-0.3-0.2-0.1-0.0-0.2-0.4-0.5-0.3
Reaction time mean minus median0.20.20.40.50.10.60.20.60.50.50.5
Reaction time mean minus median AUC0.10.10.30.30.10.50.10.50.30.50.3
Reaction time num false alarms0.50.81.40.80.71.00.60.80.81.20.9
Reaction time num false alarms AUC0.10.20.50.30.20.60.20.30.30.70.5
Reaction time trials correct on left0.10.10.2-0.3-0.2-0.1-0.0-0.2-0.4-0.5-0.3
Reaction time trials on left0.00.10.1-0.3-0.1-0.00.1-0.2-0.4-0.4-0.2
Reaction time mean0.00.00.1-0.2-0.30.1-0.20.1-0.1-0.1-0.2
Reaction time mean AUC0.00.00.1-0.1-0.30.2-0.20.2-0.0-0.1-0.0
Median of all reaction times0.10.10.2-0.5-0.5-0.1-0.3-0.1-0.4-0.4-0.3
Reaction time omissions1.92.63.51.61.81.51.91.61.41.61.5
Reaction time false alarm rate0.10.20.60.30.30.50.20.30.40.80.4
Reaction time premature initiation rate0.40.60.7-0.8-0.8-0.8-0.8-0.7-0.8-0.7-0.8
Reaction time premature initiations0.60.81.1-1.0-0.8-0.9-0.8-0.9-1.0-0.8-0.9
Std. dev. reaction times0.00.00.0-0.1-0.20.2-0.10.1-0.1-0.0-0.1
Reaction time trials completed0.00.10.1-0.3-0.1-0.00.1-0.2-0.4-0.4-0.2
Reaction time trials AUC0.00.10.1-0.3-0.1-0.00.0-0.2-0.4-0.3-0.2
Social response proportion0.20.30.5-0.70.0-0.40.1-0.4-0.7-0.6-0.6
Social responses3.24.26.31.92.12.22.52.11.81.81.9
Social time1.11.52.01.01.01.30.71.31.41.41.4
Conditioned locomotion0.10.10.3-0.00.5-0.10.50.0-0.00.2-0.0
Cocaine response after cond. corrected1.31.42.0-1.4-0.6-1.4-0.6-1.3-1.4-1.1-1.4
Cocaine response after cond. not corrected0.40.50.7-0.8-0.1-0.9-0.2-0.9-0.9-0.4-0.9
Cocaine response before conditioning2.02.43.01.61.31.71.11.51.61.71.6
Saline control response0.50.70.90.90.51.00.50.91.00.71.0
Condit. Reinf. active minus inactive responses0.70.81.20.90.90.80.90.80.91.10.9
Condit. Reinf. active-inactive response ratio0.20.30.4-0.6-0.3-0.7-0.5-0.6-0.6-0.2-0.6
Condit. Reinf. active responses1.01.41.51.21.21.11.21.11.21.21.2
Condit. Reinf. inactive responses3.03.74.32.01.91.92.11.92.01.72.0
Condit. Reinf. lever presses0.40.50.80.90.10.80.20.80.90.50.9
Condit. Reinf. lever reinforcers received0.60.81.01.00.90.80.90.81.00.91.0
Pavlov. Cond. lever latency0.30.51.50.41.20.31.10.30.30.80.3
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.50.3-0.30.20.2-0.30.2
Pavlov. Cond. change in total contacts1.11.63.9-0.8-2.0-0.9-1.7-0.8-0.8-1.5-0.8
Pavlov. Cond. index score0.20.31.3-0.1-1.2-0.0-0.9-0.1-0.1-0.7-0.1
Pavlov. Cond. latency score0.10.20.70.2-0.80.3-0.60.30.2-0.40.2
Pavlov. Cond. lever contacts0.20.31.10.1-1.10.1-0.90.10.1-0.50.1
Pavlov. Cond. magazine entry number0.20.20.4-0.60.2-0.7-0.1-0.5-0.60.1-0.6
Pavlov. Cond. intertrial magazine entries6.88.712.32.83.52.73.32.72.73.12.7
Pavlov. Cond. lever-magazine prob. diff.0.30.41.5-0.2-1.2-0.1-0.9-0.2-0.2-0.7-0.2
Pavlov. Cond. response bias0.20.31.40.1-1.20.2-0.90.00.1-0.70.1
Conditioned reinforcement - actives0.40.40.90.50.90.60.90.30.30.40.4
Conditioned reinforcement - inactives1.61.82.21.31.51.21.31.41.31.41.3
Conditioned locomotion0.00.10.2-0.00.40.20.4-0.1-0.0-0.2-0.0
Intermittent access intake day 1-15 change0.30.30.50.50.50.70.50.60.50.60.5
Intermittent access intake escalation0.10.10.10.20.20.30.20.30.20.40.2
Intermittent access intake escalation 20.10.10.20.20.10.40.10.30.30.30.2
Intermitt. access day 1 inactive lever presses0.30.30.80.30.90.50.70.70.50.50.4
Intermitt. access day 15 inactive lever presses0.10.10.2-0.3-0.4-0.2-0.5-0.0-0.4-0.3-0.3
Intermitt. access escalation Index0.00.00.10.10.20.20.1-0.2-0.10.1-0.1
Intermittent access day 1 total infusions1.21.42.1-1.2-0.9-1.3-0.9-1.3-1.0-1.5-1.2
Intermittent access day 15 total infusions0.30.40.6-0.7-0.3-0.7-0.3-0.7-0.5-0.8-0.6
Intermittent access terminal intake (last 3 days)1.61.82.2-1.4-1.1-1.5-1.2-1.5-1.2-1.5-1.4
Intermittent access total infusions0.80.81.4-1.0-0.4-1.1-0.4-1.1-0.8-1.2-1.0
Intermittent access day 1 locomotion0.10.10.10.20.4-0.10.30.00.3-0.10.2
Intermittent access day 15 total locomotion0.40.41.0-0.7-0.5-0.7-0.3-0.6-0.4-1.0-0.7
Intermittent access total locomotion0.00.00.2-0.1-0.0-0.30.1-0.20.1-0.5-0.2
Intermittent access standard deviation0.50.51.0-0.6-1.0-0.6-0.9-0.6-0.6-0.7-0.6
Cocaine induced anxiety0.20.30.50.7-0.10.5-0.00.70.70.20.7
Post-drug Anxiety3.03.34.11.91.71.71.82.01.81.71.9
Baseline Anxiety2.22.43.01.41.71.61.71.31.41.71.4
Lifetime Intake0.30.40.8-0.6-0.3-0.7-0.2-0.8-0.5-0.9-0.7
Incentive Sensitization - Responses0.30.30.4-0.5-0.6-0.4-0.6-0.4-0.6-0.4-0.5
Incentive Sensitization - Breakpoint0.10.10.2-0.3-0.5-0.2-0.5-0.2-0.5-0.3-0.4
Progressive ratio test 1 active lever presses2.93.03.9-1.8-1.3-2.0-1.2-1.9-1.7-1.9-1.8
Progressive ratio test 1 breakpoint2.93.04.0-1.8-1.2-2.0-1.2-1.9-1.7-1.9-1.8
Progressive ratio test 1 inactive lever presses0.20.20.50.40.60.40.70.40.40.10.3
Progressive ratio test 2 active lever presses2.02.12.7-1.5-1.1-1.5-1.0-1.5-1.5-1.7-1.6
Progressive ratio test 2 breakpoint1.71.92.4-1.4-1.1-1.4-1.0-1.4-1.4-1.5-1.5
Progressive ratio test 2 inactive lever presses0.20.30.6-0.4-0.3-0.5-0.3-0.4-0.6-0.8-0.5
Total sessions with >9 infusions0.20.20.50.30.60.30.70.40.30.10.3
Short access day 1 total inactive lever presses1.61.72.4-1.4-0.8-1.5-1.1-1.4-1.3-1.4-1.4
Short access day 10 total inactive lever presses0.20.20.60.20.80.40.60.30.40.40.3
Short access day 1 total infusions0.60.61.0-0.8-0.3-0.9-0.4-0.8-0.8-1.0-0.9
Short access day 10 total infusions0.40.50.8-0.5-0.9-0.6-0.8-0.8-0.4-0.9-0.5
Short access total infusions0.30.30.6-0.5-0.5-0.6-0.4-0.6-0.4-0.8-0.5
Short access day 1 locomotion0.00.00.10.1-0.30.2-0.30.10.1-0.00.1
Short access day 10 total locomotion0.60.60.70.80.80.80.80.90.80.60.8
Short access total locomotion0.70.70.80.90.70.70.80.90.90.60.9
Compulsive drug intake0.50.50.80.80.80.80.70.60.50.90.8
One hour access (0.3 mA shock)0.20.30.5-0.6-0.5-0.4-0.5-0.7-0.3-0.7-0.5
One hour access (shock baseline)0.70.81.2-1.0-0.8-0.8-0.7-1.0-0.6-1.1-0.9
Number of responses in last shaping day0.10.10.20.4-0.20.5-0.10.30.40.40.4
Context. condit. distance diff. score1.01.22.1-1.30.1-1.30.1-1.2-1.4-1.0-1.4
Locomotion velocity, session 10.91.01.31.10.81.10.80.81.11.21.0
Locomotion distance, session 11.92.53.41.80.91.91.11.41.81.51.8
Locomotion velocity, session 20.91.11.51.20.71.20.60.91.21.21.1
Locomotion distance, session 22.84.05.52.31.32.31.41.92.32.12.2
Locomotion velocity, session 31.92.22.5-1.5-1.5-1.4-1.4-1.4-1.6-1.6-1.6
Locomotion distance, session 30.60.71.0-0.8-0.6-1.0-0.6-0.8-1.0-0.8-0.9
Stereotopy head waving bouts, day 30.00.00.10.1-0.30.2-0.20.20.1-0.20.1
Stereotopy head waving duration, day 30.60.71.6-0.7-1.3-0.5-1.2-0.6-0.6-0.9-0.6
Locomotion velocity, session 70.60.60.9-0.90.6-1.00.6-0.7-0.9-0.7-1.0
Locomotion distance, session 70.50.72.50.21.60.11.60.30.30.40.2
Stereotopy head waving bouts, day 70.50.51.4-0.5-1.2-0.4-1.1-0.6-0.6-0.7-0.5
Stereotopy head waving duration, day 71.41.83.1-1.2-1.8-1.1-1.7-1.1-1.2-1.2-1.1
Locomotion velocity, session 80.40.50.8-0.7-0.6-0.8-0.5-0.9-0.8-0.6-0.8
Locomotion distance, session 80.20.30.80.40.70.40.90.20.40.40.3
Degree of sensitization distance1.81.94.60.92.21.02.01.01.11.11.0
Degree of sensitization stereotypy0.80.91.6-0.8-1.3-0.8-1.2-0.9-0.9-0.9-0.8
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.20.5-0.10.40.30.10.3
Condit. Reinf. active-inactive response ratio0.20.30.4-0.5-0.6-0.4-0.6-0.4-0.5-0.6-0.5
Condit. Reinf. active responses0.91.11.91.20.51.40.61.11.20.91.2
Condit. Reinf. inactive responses3.84.55.32.31.72.31.72.12.32.22.2
Incentive salience index mean0.20.20.50.6-0.30.7-0.30.50.50.40.5
Condit. Reinf. lever presses0.60.81.51.10.11.20.10.91.00.81.0
Time in familiar zone, hab. session 10.10.10.20.20.40.40.40.10.20.10.2
Time in novel zone, hab. session 12.62.52.9-1.6-1.6-1.7-1.6-1.5-1.6-1.5-1.6
Total zone transitions, hab. session 10.10.10.30.5-0.20.5-0.00.20.50.20.5
Total locomotion distance, hab. session 11.11.52.21.40.91.50.91.11.31.41.4
Locomotion velocity, hab. session 12.73.85.02.11.42.21.41.82.12.22.1
Time in familiar zone, hab. session 20.50.50.9-0.8-0.2-0.9-0.3-0.7-0.9-0.5-0.8
Time in novel zone, hab. session 20.30.30.60.60.20.80.20.50.70.50.6
Total zone transitions, hab. session 20.10.20.30.5-0.50.5-0.30.20.40.10.4
Total locomotion distance, hab. session 20.30.40.80.70.20.90.20.50.60.60.7
Locomotion velocity, hab. session 20.20.30.70.7-0.00.80.10.40.60.50.7
Novel to familiar place preference ratio0.50.50.80.80.60.70.50.70.90.60.8
Novelty place preference0.70.71.10.90.80.80.60.81.00.81.0
Time in novel zone, NPP test0.70.71.10.90.70.80.60.81.00.91.0
Total zone transitions, NPP test1.62.33.01.71.11.71.31.41.71.51.7
Total locomotion distance, NPP test6.18.59.53.02.73.12.82.82.92.93.0
Locomotion velocity, NPP test4.66.67.42.72.42.72.52.42.62.62.6
Pavlov. Cond. lever latency0.10.10.4-0.40.1-0.60.2-0.4-0.3-0.3-0.3
Pavlov. Cond. magazine entry latency0.00.10.2-0.1-0.40.0-0.30.0-0.2-0.3-0.2
Pavlov. Cond. change in total contacts0.50.51.7-0.3-1.3-0.1-1.2-0.4-0.3-0.8-0.3
Pavlov. Cond. index score0.10.20.5-0.1-0.70.1-0.7-0.1-0.2-0.3-0.2
Pavlov. Cond. latency score0.10.10.30.0-0.50.3-0.50.1-0.0-0.1-0.0
Pavlov. Cond. lever contacts0.10.10.20.1-0.40.3-0.50.2-0.00.1-0.0
Pavlov. Cond. magazine entry number0.40.51.20.51.10.41.00.50.60.80.6
Pavlov. Cond. intertrial magazine entries1.31.51.91.40.91.41.01.21.41.21.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.3-0.9-0.1-0.9-0.3-0.4-0.5-0.4
Pavlov. Cond. response bias0.70.81.5-0.8-1.2-0.6-1.2-0.6-0.9-0.9-0.9
Bone: apparent density1.42.32.61.51.51.51.61.41.51.51.5
Bone surface1.11.92.51.51.11.51.31.41.61.21.5
Bone volume1.22.12.51.51.21.61.41.31.61.31.5
Bone: connectivity density2.74.35.61.92.41.92.42.12.02.11.9
Bone: cortical apparent density1.41.82.5-1.5-0.8-1.6-0.9-1.4-1.5-1.2-1.5
Bone: cortical area0.10.10.3-0.1-0.5-0.2-0.5-0.5-0.1-0.5-0.1
Bone: cortical porosity0.10.10.30.2-0.50.2-0.50.10.10.20.2
Bone: cortical porosity0.10.10.30.2-0.50.3-0.50.10.20.10.2
Bone: cortical thickness0.30.50.8-0.6-0.8-0.7-0.8-0.9-0.6-0.8-0.6
Bone: cortical thickness0.70.81.6-1.0-0.4-1.0-0.7-1.3-1.0-0.7-1.0
Bone: cortical tissue density1.62.13.0-1.7-0.9-1.7-1.1-1.5-1.7-1.3-1.6
Bone: elastic displacement1.41.62.21.50.61.50.91.41.40.91.5
Bone: elastic work1.72.23.31.80.61.80.81.51.81.31.8
Bone: endosteal estimation0.10.20.30.50.20.60.30.50.60.30.6
Bone: endosteal perimeter0.81.62.21.40.81.50.91.31.41.11.4
Bone: final force0.10.10.3-0.2-0.5-0.2-0.5-0.3-0.2-0.5-0.2
Bone: final moment0.00.10.20.1-0.50.1-0.4-0.10.1-0.30.1
Bone: marrow area0.10.30.40.60.30.70.40.60.70.40.6
Bone: maximum diameter0.30.60.9-0.7-0.9-0.7-1.0-1.0-0.6-0.8-0.6
Bone: maximum force0.10.20.7-0.2-0.8-0.2-0.7-0.5-0.1-0.6-0.1
Bone: maximum moment0.10.10.40.2-0.70.2-0.6-0.10.2-0.30.2
Bone: minimum diameter0.10.10.20.3-0.50.4-0.40.10.4-0.20.4
Bone: periosteal estimation0.00.10.10.3-0.10.3-0.00.10.4-0.00.3
Bone: periosteal perimeter0.30.60.90.90.40.90.50.70.90.50.9
Bone: post-yield work1.72.43.9-1.7-1.0-1.6-1.1-2.0-1.6-1.5-1.6
Bone: stiffness0.50.70.9-0.8-0.9-0.8-0.9-0.9-0.7-0.9-0.8
Bone: tissue strength0.30.30.50.70.20.60.40.60.70.40.7
Bone: trabecular number2.13.24.21.62.01.61.91.71.72.01.7
Bone: trabecular spacing1.51.92.7-1.2-1.6-1.2-1.5-1.4-1.3-1.4-1.2
Bone: trabecular thickness0.40.50.60.70.60.70.60.60.70.80.8
Bone: trabecular tissue density0.70.91.5-0.9-1.1-0.9-1.2-0.9-1.0-0.9-0.9
Breakpoint value in progressive ratio session0.40.50.70.60.80.60.80.60.70.70.8
Distance traveled before self-admin0.20.20.6-0.3-0.8-0.1-0.7-0.5-0.3-0.5-0.4
Distance traveled after self-admin0.80.91.4-0.9-1.2-0.8-1.1-1.0-0.8-1.0-0.8
Delta time in closed arm before/after self-admin0.20.20.40.40.40.60.50.50.40.30.3
Delta time in open arm before/after self-admin0.10.10.30.20.5-0.20.50.20.20.10.2
Diff in mean of infusions in LGA sessions0.10.10.2-0.0-0.50.1-0.40.30.10.00.1
Extinction: sum of active levers before priming1.41.52.21.01.41.21.51.01.11.31.1
Active lever presses in extinction session 60.00.00.2-0.20.4-0.10.1-0.1-0.10.1-0.1
Delta distance traveled before/after self-admin1.11.21.4-1.2-1.1-1.0-1.0-1.1-1.1-1.1-1.1
Delta ambulatory time before/after self-admin0.80.91.1-1.0-1.0-0.8-0.9-0.9-0.9-1.0-0.9
Time in closed arm before self-admin0.40.40.6-0.5-0.8-0.7-0.7-0.5-0.5-0.6-0.6
Time in closed arm after self-admin0.10.10.10.3-0.20.30.10.40.30.00.1
Time in open arm before self-admin0.20.20.50.40.30.70.40.40.50.60.6
Time in open arm after self-admin0.10.10.40.20.70.20.50.20.20.30.3
Sum of active levers in priming session hrs 5-60.10.10.3-0.20.60.00.5-0.2-0.20.1-0.1
Time to tail flick, vehicle, before self-admin0.20.20.50.40.50.20.30.40.30.70.5
Time to tail flick, vehicle, after self-admin1.11.11.4-1.1-1.0-1.1-1.0-1.1-1.2-0.9-1.1
Time to tail flick, test, before self-admin0.50.50.90.80.60.50.70.70.80.70.9
Time to tail flick, test, after self-admin2.22.34.91.12.20.92.21.21.01.51.2
Delta time to tail flick, vehicle, before/after SA1.11.11.4-1.1-0.9-1.1-0.7-1.0-1.1-1.2-1.2
Delta time to tail flick, test, before/after SA0.20.20.7-0.20.8-0.20.8-0.1-0.40.1-0.4
Ambulatory time before self-admin0.20.20.4-0.3-0.5-0.2-0.6-0.4-0.3-0.4-0.3
Ambulatory time after self-admin1.21.32.3-1.0-1.5-0.8-1.3-1.1-0.9-1.2-1.0
Total heroin consumption1.01.22.6-1.1-1.2-1.0-1.6-1.0-1.0-0.8-0.9
Area under the delay curve0.20.20.4-0.3-0.6-0.2-0.5-0.5-0.2-0.5-0.2
Delay disc. indifference point, 0s delay2.42.63.61.71.21.91.41.61.81.61.7
Delay disc. indifference point, 16s delay0.40.40.6-0.6-0.7-0.5-0.5-0.8-0.6-0.8-0.4
Delay disc. indifference point, 2s delay0.70.71.31.00.31.20.40.81.01.00.8
Delay disc. indifference point, 24s delay0.70.70.9-0.8-0.9-0.6-0.8-1.0-0.7-1.0-0.6
Delay disc. indifference point, 4s delay1.01.11.8-1.0-1.3-0.9-1.2-1.0-0.9-1.0-0.9
Delay disc. indifference point, 8s delay0.60.60.9-0.8-0.8-0.9-0.9-0.8-0.7-1.0-0.6
Delay discount exponential model param0.60.61.10.71.00.60.90.80.60.90.6
Delay discount hyperbolic model param0.50.61.20.61.10.51.00.80.60.80.5
Fecal boli incidents, locomotor time 12.22.43.6-1.5-1.6-1.6-1.9-1.5-1.4-1.6-1.2
Change in fecal boli incidents, locomotor task0.10.10.20.10.10.30.50.3-0.0-0.2-0.0
Time >=10cm from walls, locomotor time 11.31.32.01.31.10.61.11.31.11.41.0
Bouts of movement, locomotor time 10.60.70.9-0.9-0.8-0.8-0.9-0.9-0.9-0.6-0.9
Total resting periods, locomotor time 11.51.72.0-1.4-1.1-1.2-1.1-1.4-1.4-1.1-1.4
Rest time, locomotor task time 12.02.22.8-1.4-1.4-1.4-1.2-1.7-1.6-1.6-1.5
Distance moved, locomotor task time 11.61.82.31.31.51.01.21.41.31.51.4
Vertical activity count, locomotor time 11.11.11.71.20.51.10.51.21.11.31.1
Time >=10cm from walls, locomotor time 20.10.10.2-0.0-0.4-0.3-0.2-0.0-0.2-0.3-0.2
Bouts of movement, locomotor time 21.51.62.4-1.3-1.3-1.0-1.1-1.4-1.3-1.1-1.5
Total resting periods, locomotor time 23.43.64.8-2.0-1.8-1.6-1.6-2.0-2.0-1.8-2.2
Rest time, locomotor task time 29.611.212.8-3.4-3.0-3.3-2.9-3.5-3.6-3.4-3.5
Distance moved, locomotor task time 24.45.16.02.41.92.01.92.32.42.52.4
Vertical activity count, locomotor time 22.32.53.61.90.81.71.01.61.81.71.7
Weight adjusted by age0.10.10.40.2-0.6-0.1-0.60.30.10.30.1
Seeking ratio, delayed vs. immediate footshock2.12.43.51.51.11.91.41.71.61.41.7
Locomotion in novel chamber0.10.10.3-0.2-0.3-0.5-0.1-0.4-0.4-0.2-0.3
Locomotion in novel chamber post-restriction0.80.91.3-0.8-1.1-0.8-0.9-1.1-0.9-1.0-1.0
Progressive ratio0.30.30.8-0.5-0.9-0.4-0.7-0.4-0.4-0.6-0.4
Food seeking constrained by brief footshock1.61.93.0-1.6-0.9-1.4-0.7-1.5-1.7-1.2-1.7
Seeking ratio, punishment vs. effort0.30.40.7-0.7-0.1-0.7-0.1-0.7-0.8-0.4-0.8
Run reversals in cocaine runway, females0.60.51.00.71.00.51.00.60.60.70.6
Run reversals in cocaine runway, males6.15.98.3-2.1-2.9-2.1-2.9-2.3-2.3-2.6-2.2
Latency to leave start box in cocaine runway1.11.22.3-0.8-1.5-0.6-1.1-0.9-1.0-1.5-1.1
Latency to leave start box in cocaine runway, F2.12.33.8-1.3-1.9-1.0-1.8-1.2-1.4-1.8-1.5
Latency to leave start box in cocaine runway, M0.90.81.41.00.70.91.20.90.80.80.8
Cd content in liver0.10.20.20.40.40.40.30.50.40.40.4
Co content in liver2.63.03.9-1.7-1.7-1.7-1.6-1.9-1.6-2.0-1.6
Cu content in liver1.21.42.3-1.2-1.2-1.2-1.2-1.1-1.1-1.5-1.1
Fe content in liver0.40.40.80.50.90.50.80.80.50.70.5
K content in liver0.30.30.80.50.80.50.90.40.40.50.4
Mg content in liver0.30.30.60.50.60.50.80.40.40.40.4
Mn content in liver2.52.84.11.71.81.72.01.51.61.41.6
Na content in liver0.40.40.70.7-0.90.7-0.60.50.60.40.6
Rb content in liver0.10.10.2-0.40.1-0.40.1-0.2-0.5-0.4-0.5
Se content in liver4.55.56.62.51.82.51.92.52.62.12.6
Sr content in liver1.31.21.51.11.11.11.21.21.10.91.1
Zn content in liver0.20.20.50.4-0.70.4-0.50.40.4-0.20.4