Hub : Genes

Mal

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability ENSRNOG00000015445 0.04 0.04 1.4e-04 0.02 0.01 0.02 0.02 9.0e-04 9.1e-03 3.3e-03 3.1e-03
2 BLA alternative TSS ENSRNOT00000020870 0.29 0.17 4.8e-12 0.18 0.18 0.18 0.15 5.2e-10 4.6e-10 5.7e-10 1.7e-08
3 BLA alternative TSS ENSRNOT00000114128 0.36 0.19 8.9e-16 0.24 0.23 0.25 0.23 3.4e-13 9.8e-13 7.6e-14 1.1e-12
4 BLA gene expression ENSRNOG00000015445 0.06 0.05 4.2e-03 0.02 0 0.01 0 2.5e-02 1.6e-01 7.7e-02 2.3e-01
5 BLA mRNA stability ENSRNOG00000015445 0.11 0.08 2.2e-05 0.08 0.04 0.07 0.01 5.1e-05 2.9e-03 1.2e-04 1.5e-01
6 Brain gene expression ENSRNOG00000015445 0.07 0.05 2.6e-07 0.07 0.06 0.07 0.06 5.6e-07 1.9e-06 9.0e-07 1.2e-06
7 Brain mRNA stability ENSRNOG00000015445 0.16 0.09 0.0e+00 0.21 0.2 0.2 0.2 2.6e-19 1.7e-18 2.2e-18 2.4e-18
8 Eye gene expression ENSRNOG00000015445 0.5 0.25 4.6e-03 0.09 -0.02 0.07 0.05 2.0e-02 6.8e-01 2.9e-02 6.6e-02
9 NAcc alternative TSS ENSRNOT00000020870 0.03 0.03 3.5e-03 0.01 0.03 0.01 0.03 4.4e-02 1.4e-03 5.8e-02 4.6e-03
10 NAcc alternative TSS ENSRNOT00000114128 0.04 0.03 4.7e-03 0.02 0.03 0.02 0.02 7.1e-03 5.4e-03 1.2e-02 1.4e-02
11 NAcc mRNA stability ENSRNOG00000015445 0.1 0.07 4.1e-05 0.06 0.02 0.05 0.03 2.4e-05 8.1e-03 8.0e-05 4.3e-03
12 PL alternative TSS ENSRNOT00000020870 0.07 0.07 4.2e-03 0.02 -0 0.01 -0 1.2e-02 7.7e-01 6.8e-02 6.2e-01
13 PL alternative TSS ENSRNOT00000114128 0.07 0.07 5.6e-03 0.02 -0 0.01 -0 1.0e-02 9.5e-01 4.2e-02 1.0e+00
14 PL mRNA stability ENSRNOG00000015445 0.06 0.06 3.9e-03 0.03 -0 0.03 -0 1.3e-03 5.3e-01 2.8e-03 7.5e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail1.23.86.02.3-1.72.01.72.51.61.82.2-2.12.01.8-1.81.71.7
BMI without tail3.26.811.43.2-2.32.72.13.42.22.43.1-2.92.72.4-2.22.22.3
Body weight4.418.827.15.2-4.04.23.94.94.04.14.7-4.74.54.1-4.04.04.1
Epididymis fat weight0.00.10.50.70.3-0.2-0.20.1-0.1-0.10.2-0.10.0-0.10.2-0.2-0.1
Glucose0.10.20.80.9-0.20.10.30.60.40.30.5-0.50.40.30.0-0.00.1
Heart weight1.62.35.92.4-1.21.21.31.71.31.41.8-1.81.61.4-1.11.21.2
Left kidney weight0.10.31.41.2-0.30.40.30.60.40.50.7-0.60.50.5-0.30.30.4
Right kidney weight0.10.41.01.0-0.40.60.41.00.40.50.7-0.60.60.5-0.40.30.4
Tail length3.19.315.43.9-2.73.02.53.72.72.83.5-3.33.22.8-2.62.72.8
Length with tail2.17.712.83.6-2.52.62.43.12.62.63.0-3.02.92.6-2.52.52.6
Length without tail0.51.11.51.2-1.00.91.10.91.01.00.9-1.11.01.0-1.11.01.1
Liver weight, left0.10.20.40.6-0.40.20.60.20.60.60.2-0.40.40.6-0.40.40.5
Liver weight, right0.50.81.0-0.51.0-1.0-0.8-1.0-1.0-0.9-0.70.8-0.9-0.91.0-1.0-0.9
Parametrial fat weight0.71.42.4-0.71.3-1.1-1.2-1.0-1.6-1.1-1.01.1-1.2-1.11.3-1.2-1.3
Retroperitoneal fat weight0.20.51.3-0.30.8-0.9-0.7-1.1-0.6-0.5-1.10.8-0.8-0.50.6-0.5-0.4
Intraocular pressure0.10.10.30.40.4-0.3-0.40.1-0.6-0.10.10.1-0.2-0.10.5-0.4-0.5
Extensor digitorum longus weight0.00.10.90.90.20.1-0.40.4-0.2-0.30.5-0.20.1-0.30.00.0-0.0
Soleus weight0.71.92.81.1-1.51.21.51.01.61.71.0-1.31.31.7-1.41.51.4
Tibialis anterior weight1.55.06.42.5-2.22.22.12.22.22.12.1-2.32.32.1-2.32.42.3
Tibia length2.57.112.93.5-2.22.91.93.62.22.13.6-3.12.92.1-2.22.22.2
Number of licking bursts0.40.50.90.80.9-0.9-0.7-0.5-0.6-0.7-0.70.5-0.6-0.70.6-0.6-0.6
Food consumed during 24 hour testing period0.50.61.3-1.10.7-0.7-0.7-0.8-0.6-0.7-0.80.8-0.8-0.70.7-0.7-0.7
Times rat made contact with spout0.10.10.2-0.1-0.40.20.3-0.20.40.30.0-0.10.20.3-0.40.40.4
Mean time between licks in bursts0.00.10.20.2-0.20.30.10.40.20.30.4-0.20.30.3-0.10.10.1
Mean num. licks in bursts0.40.51.0-1.0-0.90.80.80.10.70.70.5-0.30.50.7-0.70.70.7
Std. dev. time between licks in bursts0.80.92.11.4-0.80.80.80.90.90.91.1-1.01.00.9-0.90.90.9
Water consumed over 24 hours0.00.00.00.0-0.1-0.00.1-0.20.2-0.0-0.0-0.00.0-0.0-0.10.10.1
Indifference point 0 sec0.20.40.9-0.4-0.70.40.7-0.20.90.5-0.1-0.30.40.5-0.80.80.9
Indifference point AUC0.40.51.10.7-0.60.90.51.00.70.31.0-0.80.70.3-0.70.70.6
Indifference point function ln k0.20.30.70.3-0.60.40.80.20.50.80.3-0.50.50.8-0.60.60.6
Indifference point function log k0.20.30.70.3-0.60.40.80.20.50.80.3-0.50.50.8-0.60.60.6
Delay discounting total patch changes 0 sec0.20.40.9-0.4-0.70.40.7-0.20.90.4-0.1-0.30.40.4-0.80.81.0
Delay discounting total patch changes 12 sec0.60.81.3-0.0-1.11.10.90.81.10.80.6-0.70.80.8-1.11.01.1
Delay discounting total patch changes 18 sec0.30.41.0-0.90.5-0.6-0.5-1.0-0.2-0.7-0.90.7-0.7-0.70.4-0.4-0.3
Delay discounting total patch changes 24 sec1.01.22.2-1.30.9-1.1-0.8-1.4-0.7-1.3-1.51.2-1.1-1.30.8-0.8-0.7
Delay discounting total patch changes 6 sec0.40.61.40.2-0.90.80.80.31.20.40.4-0.60.70.4-1.11.01.1
Delay discounting time to switch 0 sec2.64.04.7-1.82.1-1.9-2.1-1.8-2.1-1.9-2.02.1-2.1-1.92.2-2.1-2.0
Delay discounting water rate 0 sec4.77.58.82.5-2.92.63.02.42.92.62.5-2.82.82.6-2.92.92.9
Delay discounting water rate 12 sec1.21.83.21.0-1.50.81.80.21.71.40.5-1.11.21.4-1.71.61.7
Delay discounting water rate 18 sec0.60.81.40.8-1.00.51.20.40.81.10.7-0.90.91.1-0.90.90.8
Delay discounting water rate 24 sec1.52.02.81.5-1.51.21.60.91.71.31.0-1.31.41.3-1.61.71.7
Delay discounting water rate 6 sec2.13.13.71.9-1.81.61.91.41.91.51.7-1.81.81.5-1.91.91.8
Locomotor activity0.50.71.91.4-0.60.80.61.00.60.71.2-1.00.90.7-0.70.70.7
Locomotor testing distance0.10.20.40.30.6-0.3-0.6-0.3-0.5-0.40.10.2-0.3-0.40.5-0.4-0.4
Locomotor testing rearing0.10.10.40.6-0.10.30.10.20.20.20.6-0.40.30.2-0.20.30.3
Light reinforcement 10.10.31.11.1-0.20.30.30.30.40.40.5-0.50.40.4-0.40.50.6
Light reinforcement 20.30.30.60.7-0.50.50.70.50.60.80.4-0.50.50.8-0.50.50.5
Reaction time number correct0.00.10.20.2-0.20.10.1-0.40.30.2-0.0-0.10.10.2-0.20.40.4
Reaction time mean minus median1.31.72.4-1.11.3-1.2-1.4-1.1-1.5-1.3-0.91.2-1.2-1.31.4-1.6-1.5
Reaction time mean minus median AUC0.60.81.4-0.80.9-0.8-0.9-0.6-1.1-1.0-0.40.8-0.8-1.01.0-1.2-1.2
Reaction time num false alarms3.85.26.61.6-2.42.42.42.62.42.32.2-2.32.42.3-2.22.32.4
Reaction time num false alarms AUC4.56.48.31.7-2.62.72.62.92.62.52.4-2.62.62.5-2.42.52.6
Reaction time trials correct on left0.00.10.20.2-0.20.10.1-0.40.30.2-0.0-0.10.10.2-0.20.40.4
Reaction time trials on left0.10.10.20.2-0.30.10.2-0.30.40.20.1-0.10.20.2-0.30.50.4
Reaction time mean0.10.20.40.2-0.40.40.50.60.20.60.6-0.50.50.6-0.40.20.2
Reaction time mean AUC0.10.10.30.1-0.30.30.40.50.10.50.5-0.40.40.5-0.30.10.1
Median of all reaction times0.50.71.10.5-0.80.80.91.00.61.00.9-0.90.91.0-0.80.70.6
Reaction time omissions0.20.30.70.2-0.50.70.30.80.20.60.9-0.60.60.6-0.50.40.3
Reaction time false alarm rate3.44.87.21.3-2.32.42.32.72.22.22.1-2.22.32.2-2.12.12.2
Reaction time premature initiation rate0.20.20.60.80.7-0.5-0.6-0.5-0.7-0.60.10.1-0.3-0.60.3-0.3-0.5
Reaction time premature initiations0.20.20.70.60.6-0.5-0.6-0.8-0.6-0.5-0.10.2-0.4-0.50.2-0.2-0.4
Std. dev. reaction times0.20.20.70.5-0.40.50.30.70.20.60.8-0.60.60.6-0.30.20.2
Reaction time trials completed0.10.10.20.2-0.30.10.2-0.30.40.20.1-0.10.20.2-0.30.50.4
Reaction time trials AUC0.00.10.20.2-0.20.10.1-0.30.30.20.1-0.10.10.2-0.20.40.3
Social response proportion0.30.30.60.5-0.50.70.50.70.40.80.7-0.60.60.8-0.40.50.4
Social responses2.93.85.51.8-1.92.21.62.21.71.92.3-2.12.01.9-1.81.91.9
Social time0.40.50.80.4-0.70.90.60.70.70.70.7-0.70.70.7-0.80.80.8
Conditioned locomotion7.18.410.21.3-3.23.13.12.63.03.12.6-2.72.93.1-3.23.23.2
Cocaine response after cond. corrected0.40.41.2-0.0-0.70.50.80.20.51.10.2-0.40.51.1-0.70.70.7
Cocaine response after cond. not corrected0.10.10.4-0.2-0.40.30.40.10.10.60.2-0.20.20.6-0.30.30.2
Cocaine response before conditioning0.80.91.9-0.51.0-0.7-1.1-0.4-1.1-1.4-0.30.7-0.7-1.41.1-1.1-1.1
Saline control response4.05.47.52.2-2.32.42.21.92.51.92.1-2.32.31.9-2.72.72.7
Condit. Reinf. active minus inactive responses1.41.72.61.6-1.21.41.11.41.30.91.4-1.41.30.9-1.41.41.3
Condit. Reinf. active-inactive response ratio1.21.23.31.8-0.91.00.91.21.10.81.2-1.21.10.8-1.11.11.0
Condit. Reinf. active responses2.83.94.52.0-2.02.11.82.01.91.72.1-2.12.11.7-2.12.12.0
Condit. Reinf. inactive responses0.91.21.40.6-1.21.11.21.01.01.11.2-1.11.21.1-1.11.11.1
Condit. Reinf. lever presses0.71.01.41.1-0.91.00.70.91.20.71.0-1.01.00.7-1.11.11.1
Condit. Reinf. lever reinforcers received2.02.83.11.7-1.71.71.51.71.61.41.8-1.81.71.4-1.81.81.7
Pavlov. Cond. lever latency1.72.33.1-1.81.5-1.4-1.5-1.2-1.6-1.3-1.51.6-1.5-1.31.7-1.7-1.7
Pavlov. Cond. magazine entry latency0.20.20.30.3-0.50.40.50.10.40.50.5-0.40.40.5-0.50.50.4
Pavlov. Cond. change in total contacts1.41.93.11.6-1.31.41.21.41.21.31.8-1.51.51.3-1.31.31.2
Pavlov. Cond. index score1.82.32.61.5-1.61.41.51.21.61.51.6-1.61.61.5-1.61.61.5
Pavlov. Cond. latency score1.31.61.91.2-1.31.21.30.91.31.31.4-1.31.31.3-1.41.41.3
Pavlov. Cond. lever contacts1.92.63.31.7-1.61.51.61.21.81.41.6-1.71.61.4-1.71.71.8
Pavlov. Cond. magazine entry number0.50.61.2-1.00.7-0.7-0.7-0.7-0.6-0.9-1.10.9-0.9-0.90.7-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.30.8-1.0-0.6-0.9-0.5-0.8-1.10.8-0.9-0.80.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.62.02.31.3-1.51.31.41.11.51.41.5-1.51.51.4-1.51.51.4
Pavlov. Cond. response bias2.33.23.61.9-1.81.71.81.61.91.71.9-1.91.91.7-1.81.81.8
Conditioned reinforcement - actives0.20.21.00.9-0.10.30.11.0-0.10.20.6-0.50.40.2-0.10.1-0.1
Conditioned reinforcement - inactives1.71.92.41.1-1.41.21.51.11.51.51.1-1.41.41.5-1.51.41.5
Conditioned locomotion0.10.10.50.7-0.00.10.10.7-0.00.00.4-0.30.20.0-0.00.0-0.0
Intermittent access intake day 1-15 change2.82.83.41.5-1.71.71.71.71.61.61.7-1.71.71.6-1.91.81.6
Intermittent access intake escalation2.22.22.61.4-1.41.51.41.61.41.41.5-1.61.51.4-1.61.51.4
Intermittent access intake escalation 20.40.40.70.4-0.70.80.70.80.60.50.6-0.70.70.5-0.80.70.6
Intermitt. access day 1 inactive lever presses2.72.94.01.0-1.81.71.81.61.72.01.5-1.71.72.0-1.81.71.7
Intermitt. access day 15 inactive lever presses0.30.30.70.4-0.70.20.8-0.00.70.70.2-0.50.50.7-0.80.60.7
Intermitt. access escalation Index0.20.10.4-0.7-0.50.30.3-0.20.50.10.1-0.10.20.1-0.50.50.5
Intermittent access day 1 total infusions0.20.30.4-0.50.6-0.5-0.6-0.2-0.6-0.3-0.60.5-0.5-0.30.4-0.6-0.6
Intermittent access day 15 total infusions0.80.91.41.0-0.91.00.91.20.90.90.9-1.01.00.9-1.10.90.9
Intermittent access terminal intake (last 3 days)0.30.40.70.5-0.50.70.60.90.50.50.5-0.60.60.5-0.70.60.5
Intermittent access total infusions0.00.00.20.20.00.10.00.4-0.00.20.1-0.10.10.2-0.20.0-0.0
Intermittent access day 1 locomotion0.20.20.40.5-0.40.30.40.70.30.40.3-0.40.40.4-0.40.30.3
Intermittent access day 15 total locomotion0.20.20.40.4-0.30.30.40.70.20.60.5-0.50.50.6-0.30.20.2
Intermittent access total locomotion0.50.51.20.9-0.60.70.71.10.50.70.8-0.80.80.7-0.60.40.5
Intermittent access standard deviation0.30.41.00.3-0.60.60.70.40.70.30.2-0.50.50.3-1.00.80.7
Cocaine induced anxiety5.05.810.6-3.22.1-2.4-2.0-3.0-1.9-2.2-3.12.7-2.6-2.21.8-1.9-1.9
Post-drug Anxiety1.71.93.7-1.91.1-1.3-1.2-1.8-1.2-1.3-1.61.5-1.4-1.31.0-1.1-1.2
Baseline Anxiety1.31.43.01.7-1.01.20.91.50.81.01.7-1.41.31.0-0.70.90.8
Lifetime Intake0.10.10.50.5-0.20.40.20.70.10.50.4-0.40.30.5-0.30.20.1
Incentive Sensitization - Responses0.10.10.20.10.4-0.2-0.3-0.1-0.5-0.0-0.00.2-0.3-0.00.2-0.3-0.5
Incentive Sensitization - Breakpoint0.20.20.3-0.10.5-0.4-0.4-0.3-0.6-0.2-0.30.4-0.4-0.20.4-0.4-0.6
Progressive ratio test 1 active lever presses1.61.72.71.6-1.11.21.11.61.01.31.5-1.41.41.3-1.11.01.0
Progressive ratio test 1 breakpoint2.02.03.11.7-1.31.41.21.71.21.41.6-1.61.51.4-1.31.21.2
Progressive ratio test 1 inactive lever presses0.60.71.30.7-0.80.80.81.10.70.81.0-0.90.90.8-0.70.60.7
Progressive ratio test 2 active lever presses0.20.20.50.40.5-0.3-0.50.2-0.7-0.20.10.2-0.3-0.20.4-0.6-0.7
Progressive ratio test 2 breakpoint0.20.20.50.20.6-0.3-0.60.1-0.7-0.20.10.2-0.3-0.20.5-0.6-0.7
Progressive ratio test 2 inactive lever presses0.40.51.10.9-0.50.60.61.10.41.00.7-0.70.71.0-0.60.40.4
Total sessions with >9 infusions0.10.10.30.30.4-0.1-0.50.4-0.5-0.20.10.2-0.2-0.20.4-0.4-0.5
Short access day 1 total inactive lever presses1.21.41.90.4-1.31.21.21.11.21.30.8-1.01.11.3-1.41.31.2
Short access day 10 total inactive lever presses0.30.42.6-1.6-0.1-0.30.2-0.90.1-0.0-1.10.6-0.4-0.0-0.20.10.1
Short access day 1 total infusions0.00.00.1-0.0-0.10.2-0.00.30.00.20.2-0.10.10.2-0.10.00.0
Short access day 10 total infusions0.10.10.10.20.3-0.1-0.40.2-0.3-0.1-0.10.2-0.2-0.10.2-0.3-0.3
Short access total infusions0.00.00.20.2-0.10.20.00.40.00.30.2-0.10.10.3-0.20.10.0
Short access day 1 locomotion0.30.30.5-0.50.5-0.4-0.7-0.3-0.5-0.5-0.30.5-0.5-0.50.6-0.6-0.5
Short access day 10 total locomotion1.51.72.71.3-1.31.21.31.61.11.31.4-1.41.41.3-1.21.01.1
Short access total locomotion0.30.30.70.6-0.50.50.50.80.40.40.6-0.60.60.4-0.50.40.4
Compulsive drug intake0.10.10.3-0.5-0.2-0.10.3-0.40.30.1-0.40.1-0.00.1-0.10.10.3
One hour access (0.3 mA shock)1.51.72.51.1-1.31.31.41.61.21.51.2-1.31.31.5-1.41.11.2
One hour access (shock baseline)0.20.21.10.6-0.30.60.31.00.10.50.6-0.50.40.5-0.40.20.1
Number of responses in last shaping day0.80.81.10.9-0.90.70.80.80.81.10.8-0.90.91.1-1.00.80.8
Context. condit. distance diff. score0.20.21.01.0-0.30.00.5-0.10.50.40.1-0.40.30.4-0.50.50.5
Locomotion velocity, session 10.10.10.6-0.8-0.20.5-0.10.40.20.00.2-0.00.10.0-0.20.10.2
Locomotion distance, session 11.11.42.20.5-1.31.01.50.91.31.40.9-1.11.21.4-1.21.21.3
Locomotion velocity, session 20.70.81.2-0.2-1.01.10.91.01.00.90.6-0.70.80.9-1.01.01.0
Locomotion distance, session 23.65.26.11.4-2.42.32.52.22.42.52.0-2.22.32.5-2.32.32.4
Locomotion velocity, session 31.11.22.51.3-1.01.10.91.40.90.91.6-1.31.20.9-0.90.91.0
Locomotion distance, session 36.87.412.53.5-2.52.62.53.12.32.33.5-3.13.02.3-2.32.32.3
Stereotopy head waving bouts, day 31.21.42.9-1.71.0-1.1-1.0-1.6-1.0-1.0-1.51.4-1.3-1.00.8-0.8-0.9
Stereotopy head waving duration, day 31.21.53.3-1.81.0-1.1-1.0-1.6-1.0-1.0-1.71.5-1.4-1.00.8-0.8-0.9
Locomotion velocity, session 71.11.23.31.8-0.81.00.81.20.90.71.4-1.31.10.7-1.11.01.0
Locomotion distance, session 70.81.05.32.3-0.60.60.70.90.70.51.2-1.11.00.5-0.90.80.8
Stereotopy head waving bouts, day 70.10.20.30.1-0.40.40.30.20.60.40.3-0.30.30.4-0.50.50.5
Stereotopy head waving duration, day 70.00.00.1-0.3-0.10.10.1-0.10.10.2-0.00.00.00.2-0.00.10.1
Locomotion velocity, session 82.02.43.50.7-1.71.61.61.31.91.51.1-1.41.51.5-1.81.81.9
Locomotion distance, session 84.46.58.02.4-2.62.22.82.12.82.72.1-2.62.62.7-2.72.72.7
Degree of sensitization distance2.22.24.0-1.11.5-1.7-1.4-1.9-1.3-1.4-2.01.6-1.6-1.41.2-1.2-1.2
Degree of sensitization stereotypy1.01.11.31.1-1.01.01.01.11.21.11.1-1.11.11.1-1.01.01.0
Condit. Reinf. active minus inactive responses0.20.20.30.1-0.50.40.50.40.60.50.3-0.40.40.5-0.30.40.4
Condit. Reinf. active-inactive response ratio0.50.50.80.5-0.80.60.90.40.90.90.5-0.70.70.9-0.70.70.8
Condit. Reinf. active responses0.00.00.1-0.2-0.10.10.10.10.30.00.1-0.10.10.0-0.00.10.1
Condit. Reinf. inactive responses0.10.10.3-0.50.3-0.2-0.4-0.2-0.1-0.5-0.30.3-0.3-0.50.3-0.2-0.2
Incentive salience index mean0.10.10.2-0.2-0.40.20.50.10.50.40.2-0.20.30.4-0.20.30.3
Condit. Reinf. lever presses0.00.00.1-0.1-0.10.10.10.10.20.10.2-0.10.10.1-0.00.00.1
Time in familiar zone, hab. session 11.21.11.7-0.51.2-1.1-1.3-1.0-1.1-1.0-0.91.1-1.1-1.01.1-1.1-1.2
Time in novel zone, hab. session 10.40.40.8-0.0-0.80.40.90.30.70.70.2-0.50.60.7-0.70.70.7
Total zone transitions, hab. session 10.71.01.50.7-1.00.91.21.20.91.21.1-1.11.11.2-0.70.70.8
Total locomotion distance, hab. session 11.11.62.10.8-1.41.31.41.21.41.21.1-1.31.31.2-1.31.31.4
Locomotion velocity, hab. session 11.21.82.30.9-1.41.31.41.21.51.31.2-1.31.41.3-1.41.41.4
Time in familiar zone, hab. session 20.70.71.9-1.40.7-0.7-0.8-1.3-0.5-0.6-1.11.0-0.9-0.60.4-0.5-0.5
Time in novel zone, hab. session 20.50.51.81.4-0.40.50.61.10.30.40.9-0.80.70.4-0.30.30.4
Total zone transitions, hab. session 24.25.46.21.8-2.42.32.52.32.42.42.2-2.42.42.4-2.32.32.4
Total locomotion distance, hab. session 22.33.04.50.7-1.91.71.91.32.11.81.2-1.51.61.8-2.12.12.1
Locomotion velocity, hab. session 21.82.53.90.3-1.81.61.81.12.01.60.9-1.31.41.6-1.91.91.9
Novel to familiar place preference ratio0.00.00.2-0.10.0-0.10.1-0.30.10.1-0.40.2-0.20.1-0.10.10.1
Novelty place preference0.10.10.4-0.30.2-0.2-0.1-0.5-0.0-0.1-0.60.4-0.4-0.1-0.00.10.0
Time in novel zone, NPP test0.10.10.4-0.20.2-0.3-0.2-0.5-0.1-0.1-0.60.4-0.4-0.10.00.0-0.0
Total zone transitions, NPP test1.01.42.00.8-1.21.11.41.11.31.41.0-1.21.21.4-1.11.21.2
Total locomotion distance, NPP test1.21.62.60.8-1.31.21.40.91.61.30.8-1.21.21.3-1.51.51.5
Locomotion velocity, NPP test0.91.42.20.5-1.21.11.40.71.51.30.6-1.01.01.3-1.41.41.4
Pavlov. Cond. lever latency0.20.20.50.7-0.40.30.40.50.40.50.4-0.50.40.5-0.40.40.4
Pavlov. Cond. magazine entry latency0.10.10.20.20.3-0.2-0.40.2-0.4-0.40.10.1-0.1-0.40.5-0.4-0.4
Pavlov. Cond. change in total contacts0.20.20.30.00.5-0.3-0.5-0.1-0.5-0.5-0.10.3-0.3-0.50.5-0.5-0.5
Pavlov. Cond. index score0.30.40.6-0.30.6-0.4-0.7-0.2-0.7-0.8-0.20.5-0.5-0.80.8-0.8-0.7
Pavlov. Cond. latency score0.30.40.6-0.60.7-0.5-0.7-0.4-0.8-0.8-0.40.6-0.6-0.80.8-0.8-0.7
Pavlov. Cond. lever contacts0.00.00.1-0.2-0.00.10.00.2-0.1-0.00.3-0.00.0-0.00.1-0.1-0.1
Pavlov. Cond. magazine entry number0.20.30.6-0.8-0.40.10.5-0.60.50.6-0.60.1-0.00.6-0.60.60.5
Pavlov. Cond. intertrial magazine entries0.60.71.00.4-0.90.80.90.70.90.90.6-0.80.80.9-1.01.01.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.20.4-0.3-0.5-0.0-0.5-0.6-0.00.3-0.3-0.60.6-0.6-0.5
Pavlov. Cond. response bias0.10.10.50.7-0.10.30.10.70.1-0.10.7-0.40.3-0.10.1-0.00.0
Bone: apparent density1.21.92.61.6-1.41.31.41.21.61.21.2-1.41.41.2-1.51.51.5
Bone surface0.81.42.31.5-1.11.11.11.11.21.11.2-1.21.21.1-1.21.21.1
Bone volume0.91.52.11.5-1.21.21.21.11.41.11.1-1.31.21.1-1.31.41.3
Bone: connectivity density0.20.41.31.1-0.50.40.50.70.50.50.7-0.70.60.5-0.50.50.4
Bone: cortical apparent density0.20.30.70.3-0.50.80.30.90.30.30.9-0.60.60.3-0.40.50.4
Bone: cortical area2.64.05.02.1-1.92.11.82.22.01.72.2-2.12.11.7-1.91.91.9
Bone: cortical porosity0.10.10.2-0.30.10.0-0.20.4-0.3-0.30.3-0.00.0-0.30.4-0.4-0.4
Bone: cortical porosity0.20.20.70.3-0.40.50.20.80.30.10.8-0.50.50.1-0.10.10.2
Bone: cortical thickness0.61.02.20.8-1.01.30.71.40.80.61.5-1.11.10.6-0.80.80.7
Bone: cortical thickness0.20.31.10.6-0.40.60.20.90.30.21.0-0.70.60.2-0.20.20.1
Bone: cortical tissue density0.20.20.50.1-0.50.70.30.70.20.30.7-0.50.50.3-0.40.40.3
Bone: elastic displacement0.20.20.70.5-0.30.40.10.80.20.30.8-0.50.50.3-0.00.00.1
Bone: elastic work0.10.10.50.5-0.20.5-0.00.70.20.10.7-0.40.40.1-0.20.20.2
Bone: endosteal estimation0.51.13.61.9-0.80.70.90.81.00.90.8-1.00.90.9-1.01.01.0
Bone: endosteal perimeter1.63.34.92.2-1.71.71.81.71.91.71.7-1.91.81.7-1.91.91.9
Bone: final force3.35.36.22.5-2.32.32.22.42.52.02.3-2.42.42.0-2.32.42.3
Bone: final moment2.64.35.42.3-2.02.11.92.12.21.82.1-2.22.11.8-2.12.22.1
Bone: marrow area0.51.03.41.8-0.80.70.90.81.00.90.8-1.00.90.9-1.01.01.0
Bone: maximum diameter4.37.88.32.9-2.72.72.72.72.92.72.7-2.92.82.7-2.82.82.8
Bone: maximum force0.50.91.11.1-0.90.90.90.91.00.70.9-1.00.90.7-1.01.01.0
Bone: maximum moment0.20.40.70.8-0.60.70.60.60.80.40.7-0.70.70.4-0.70.70.7
Bone: minimum diameter1.32.33.21.8-1.41.61.31.71.51.21.7-1.61.61.2-1.51.51.5
Bone: periosteal estimation1.93.96.72.6-1.81.91.82.02.01.72.0-2.12.01.7-2.02.02.0
Bone: periosteal perimeter2.13.44.42.1-1.81.81.81.91.91.61.9-1.91.91.6-1.91.91.8
Bone: post-yield work0.81.11.5-1.01.0-1.1-1.0-0.9-1.1-1.0-0.81.0-1.0-1.01.2-1.2-1.2
Bone: stiffness1.72.73.51.1-1.81.71.81.41.91.51.4-1.61.71.5-1.81.81.8
Bone: tissue strength0.20.20.30.4-0.40.30.40.10.60.30.1-0.30.30.3-0.50.60.5
Bone: trabecular number1.62.43.71.9-1.51.41.61.51.61.51.4-1.61.61.5-1.61.61.6
Bone: trabecular spacing0.30.40.9-0.90.6-0.6-0.6-0.6-0.6-0.4-0.70.7-0.7-0.40.7-0.7-0.7
Bone: trabecular thickness0.60.71.00.8-0.91.00.80.90.80.70.8-0.90.90.7-0.91.00.9
Bone: trabecular tissue density1.11.62.01.0-1.21.41.11.41.01.31.4-1.31.31.3-1.21.31.2
Breakpoint value in progressive ratio session0.80.91.70.6-0.91.01.01.00.80.91.3-1.11.10.9-0.90.80.9
Distance traveled before self-admin2.02.13.51.9-1.31.31.41.61.51.41.5-1.61.51.4-1.31.31.4
Distance traveled after self-admin1.81.93.31.8-1.21.21.21.51.31.51.4-1.51.41.5-1.21.21.3
Delta time in closed arm before/after self-admin0.30.32.0-1.40.2-0.3-0.2-0.4-0.4-0.2-0.70.5-0.5-0.20.1-0.2-0.4
Delta time in open arm before/after self-admin0.20.21.01.0-0.30.30.30.50.40.30.4-0.40.40.3-0.10.30.4
Diff in mean of infusions in LGA sessions1.01.21.7-1.31.0-1.1-1.0-1.2-1.1-0.8-1.01.1-1.1-0.81.1-1.1-1.1
Extinction: sum of active levers before priming0.10.10.30.1-0.20.30.10.40.1-0.00.5-0.40.3-0.0-0.30.20.1
Active lever presses in extinction session 60.20.11.4-1.2-0.20.10.3-0.20.30.1-0.30.1-0.00.1-0.30.30.3
Delta distance traveled before/after self-admin0.00.00.1-0.0-0.00.10.00.2-0.00.30.2-0.20.10.3-0.00.00.1
Delta ambulatory time before/after self-admin1.31.41.6-1.21.2-1.1-1.3-1.1-1.3-1.0-1.21.2-1.2-1.01.3-1.2-1.2
Time in closed arm before self-admin0.10.10.3-0.00.2-0.2-0.5-0.5-0.2-0.4-0.00.3-0.3-0.40.3-0.2-0.1
Time in closed arm after self-admin0.20.21.5-1.20.1-0.1-0.3-0.4-0.2-0.3-0.30.4-0.3-0.30.2-0.1-0.2
Time in open arm before self-admin0.20.20.4-0.50.5-0.5-0.2-0.3-0.5-0.2-0.60.5-0.5-0.20.4-0.4-0.5
Time in open arm after self-admin0.10.10.30.50.5-0.4-0.3-0.2-0.4-0.3-0.50.3-0.4-0.30.5-0.4-0.4
Sum of active levers in priming session hrs 5-60.20.20.30.3-0.40.30.40.30.50.60.6-0.40.40.6-0.30.30.4
Time to tail flick, vehicle, before self-admin2.02.12.9-0.71.6-1.6-1.5-1.4-1.6-1.2-1.51.4-1.5-1.21.4-1.5-1.7
Time to tail flick, vehicle, after self-admin0.10.10.3-0.4-0.40.40.30.20.40.20.4-0.30.30.2-0.60.50.4
Time to tail flick, test, before self-admin0.80.81.61.3-0.91.00.81.10.70.81.2-1.00.90.8-0.60.80.7
Time to tail flick, test, after self-admin1.71.72.0-1.21.2-1.3-1.2-1.4-1.3-1.4-1.41.4-1.4-1.41.3-1.2-1.2
Delta time to tail flick, vehicle, before/after SA3.43.34.50.5-2.01.91.91.72.01.71.9-1.81.81.7-2.02.02.1
Delta time to tail flick, test, before/after SA1.61.42.5-1.61.1-1.3-1.0-1.6-0.8-1.1-1.61.3-1.3-1.10.8-0.9-0.8
Ambulatory time before self-admin1.51.64.12.0-1.01.11.11.61.21.11.3-1.41.31.1-1.01.11.1
Ambulatory time after self-admin0.80.92.21.5-0.70.80.71.20.80.91.1-1.11.00.9-0.60.70.7
Total heroin consumption1.61.92.51.2-1.41.31.30.91.51.41.5-1.41.41.4-1.41.41.6
Area under the delay curve0.50.60.8-0.60.8-0.9-0.7-0.8-0.7-0.7-0.60.7-0.7-0.70.9-0.8-0.7
Delay disc. indifference point, 0s delay3.43.76.3-2.51.8-1.8-1.8-2.0-1.8-1.7-2.22.1-2.0-1.71.9-1.8-1.8
Delay disc. indifference point, 16s delay0.90.91.3-0.81.0-1.1-0.9-1.1-0.9-0.8-1.11.0-1.0-0.81.0-0.9-0.9
Delay disc. indifference point, 2s delay0.10.10.3-0.30.4-0.5-0.3-0.5-0.3-0.3-0.30.3-0.3-0.30.4-0.3-0.3
Delay disc. indifference point, 24s delay1.71.62.1-1.31.2-1.2-1.3-1.2-1.3-1.4-1.21.3-1.3-1.41.3-1.2-1.2
Delay disc. indifference point, 4s delay0.10.10.40.10.5-0.3-0.50.0-0.5-0.40.10.1-0.2-0.40.7-0.5-0.5
Delay disc. indifference point, 8s delay0.70.71.0-0.31.0-0.9-0.9-0.8-0.9-0.9-0.50.7-0.8-0.91.0-1.0-0.9
Delay discount exponential model param0.40.50.80.5-0.70.80.70.70.70.70.5-0.60.70.7-0.90.70.7
Delay discount hyperbolic model param0.30.40.60.5-0.60.70.60.60.60.60.4-0.60.60.6-0.80.70.6
Fecal boli incidents, locomotor time 10.00.00.10.00.2-0.2-0.2-0.1-0.2-0.2-0.30.2-0.2-0.20.2-0.2-0.2
Change in fecal boli incidents, locomotor task0.00.00.1-0.1-0.00.0-0.1-0.2-0.00.20.3-0.10.10.2-0.0-0.1-0.0
Time >=10cm from walls, locomotor time 10.50.50.60.7-0.70.70.70.70.70.70.8-0.70.70.7-0.70.60.8
Bouts of movement, locomotor time 12.22.57.2-2.71.2-1.3-1.5-1.5-1.4-1.3-1.41.7-1.5-1.31.6-1.6-1.4
Total resting periods, locomotor time 11.31.45.5-2.40.8-0.9-1.0-1.2-0.9-0.8-1.21.3-1.2-0.81.1-1.1-1.0
Rest time, locomotor task time 10.10.20.6-0.50.3-0.3-0.3-0.6-0.2-0.4-0.80.4-0.4-0.40.0-0.1-0.3
Distance moved, locomotor task time 10.00.00.0-0.1-0.1-0.00.1-0.00.00.00.2-0.10.10.00.20.00.1
Vertical activity count, locomotor time 10.40.50.70.2-0.70.60.80.70.70.80.8-0.60.60.8-0.50.60.7
Time >=10cm from walls, locomotor time 20.00.00.40.60.0-0.20.1-0.40.1-0.1-0.0-0.10.0-0.1-0.10.00.1
Bouts of movement, locomotor time 20.60.61.0-0.60.8-0.7-1.0-0.5-0.9-1.0-0.40.7-0.7-1.00.7-0.8-0.9
Total resting periods, locomotor time 20.40.40.7-0.40.7-0.5-0.8-0.2-0.8-0.8-0.20.5-0.5-0.80.6-0.7-0.8
Rest time, locomotor task time 20.00.00.2-0.3-0.20.30.10.5-0.00.2-0.0-0.00.10.2-0.10.0-0.0
Distance moved, locomotor task time 20.20.20.9-0.50.3-0.6-0.3-0.9-0.2-0.4-0.50.4-0.4-0.40.4-0.2-0.2
Vertical activity count, locomotor time 20.10.10.3-0.1-0.50.20.6-0.10.60.40.1-0.20.30.4-0.50.40.5
Weight adjusted by age2.22.54.72.2-1.31.41.21.41.81.51.3-1.61.51.5-1.61.81.7
Seeking ratio, delayed vs. immediate footshock0.00.00.2-0.2-0.20.20.2-0.10.20.40.0-0.00.10.4-0.20.20.2
Locomotion in novel chamber0.60.71.51.2-0.80.60.80.80.70.90.9-0.90.90.9-0.60.70.7
Locomotion in novel chamber post-restriction2.12.54.51.0-1.61.61.52.01.31.62.1-1.71.71.6-1.41.21.3
Progressive ratio5.05.88.8-2.92.2-2.4-2.3-3.0-2.2-2.1-2.62.6-2.5-2.12.2-2.2-2.2
Food seeking constrained by brief footshock1.21.42.10.6-1.41.21.30.81.41.10.9-1.11.21.1-1.41.41.4
Seeking ratio, punishment vs. effort6.07.49.02.8-2.82.72.73.02.62.52.8-2.82.82.5-2.72.72.6
Run reversals in cocaine runway, females2.02.03.01.7-1.31.31.31.41.31.61.5-1.41.41.6-1.21.21.4
Run reversals in cocaine runway, males2.92.84.41.3-1.61.91.52.11.61.61.8-1.71.71.6-1.61.61.6
Latency to leave start box in cocaine runway1.61.82.4-1.31.3-1.1-1.3-0.9-1.5-1.3-1.11.4-1.4-1.31.6-1.5-1.5
Latency to leave start box in cocaine runway, F1.92.03.0-1.71.3-1.2-1.5-1.1-1.6-1.4-0.91.4-1.4-1.41.6-1.6-1.6
Latency to leave start box in cocaine runway, M0.20.21.1-0.20.3-0.5-0.1-0.3-0.2-0.1-1.00.5-0.5-0.10.2-0.2-0.2
Cd content in liver0.10.10.40.6-0.20.30.10.30.10.20.5-0.40.30.2-0.20.30.1
Co content in liver1.51.72.91.1-1.31.41.21.71.01.31.6-1.41.41.3-1.11.21.1
Cu content in liver2.63.13.61.6-1.81.81.71.91.81.51.9-1.91.91.5-1.71.71.8
Fe content in liver0.30.40.60.5-0.70.40.70.30.70.60.3-0.50.60.6-0.70.70.8
K content in liver2.62.63.60.4-1.81.71.71.41.91.71.4-1.51.61.7-1.81.61.9
Mg content in liver4.34.45.31.1-2.32.22.12.12.32.32.0-2.02.12.3-2.22.02.3
Mn content in liver3.64.15.61.3-2.22.02.11.62.42.01.7-2.02.02.0-2.32.22.3
Na content in liver0.00.10.1-0.2-0.20.20.20.10.30.3-0.2-0.00.10.3-0.30.20.3
Rb content in liver3.84.85.91.8-2.32.32.32.42.12.02.4-2.32.32.0-2.12.12.1
Se content in liver2.02.52.91.5-1.61.51.51.41.71.71.3-1.51.51.7-1.71.71.7
Sr content in liver1.11.01.41.0-1.00.90.90.81.11.20.8-1.01.01.2-1.11.11.1
Zn content in liver0.20.20.40.2-0.40.60.30.70.40.50.6-0.50.50.5-0.40.40.4