Hub : Genes

Kpna2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000015329 0.31 0.09 0.0e+00 0.36 0.34 0.36 0.36 2.5e-42 1.6e-38 5.8e-41 1.1e-41
2 Adipose mRNA stability ENSRNOG00000015329 0.03 0.02 3.8e-03 0.01 0.01 0.01 0 6.7e-02 2.7e-02 5.1e-02 8.1e-02
3 BLA gene expression ENSRNOG00000015329 0.07 0.04 7.5e-04 0.02 0.03 0.01 0.04 3.1e-02 6.1e-03 5.2e-02 4.3e-03
4 Brain gene expression ENSRNOG00000015329 0.13 0.08 3.5e-08 0.07 0.06 0.07 0.06 1.9e-07 7.2e-06 6.6e-07 1.7e-06
5 IL gene expression ENSRNOG00000015329 0.29 0.12 1.8e-04 0.1 0.14 0.12 0.12 2.9e-03 2.5e-04 7.9e-04 6.8e-04
6 LHb gene expression ENSRNOG00000015329 0.22 0.1 1.0e-03 0.02 0.07 0.01 0.05 1.2e-01 8.6e-03 1.4e-01 2.5e-02
7 Liver gene expression ENSRNOG00000015329 0.13 0.06 8.6e-10 0.07 0.06 0.08 0.06 8.9e-08 1.5e-07 5.5e-09 1.5e-07
8 NAcc gene expression ENSRNOG00000015329 0.14 0.06 6.4e-12 0.16 0.12 0.13 0.14 4.2e-12 3.1e-09 6.5e-10 2.6e-10
9 PL gene expression ENSRNOG00000015329 0.11 0.05 3.1e-08 0.06 0.09 0.08 0.09 4.8e-05 4.1e-07 1.8e-06 3.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
BMI with tail0.72.35.30.80.8-1.4-0.8-2.1-1.52.3-0.2-2.3
BMI without tail2.96.113.1-0.22.1-2.4-2.1-2.7-2.43.6-1.8-3.3
Body weight2.410.315.8-1.63.8-3.3-3.6-2.4-2.54.0-3.0-4.0
Epididymis fat weight1.94.59.6-2.00.2-1.8-1.9-3.1-2.81.9-1.9-2.1
Glucose1.01.52.01.1-0.91.41.21.01.1-1.31.41.4
Heart weight0.10.10.90.90.30.10.50.30.00.10.10.2
Left kidney weight0.61.76.42.51.10.51.01.41.4-0.11.60.1
Right kidney weight0.41.03.11.81.20.10.61.11.2-0.21.2-0.2
Tail length1.75.38.1-2.02.4-2.1-2.7-1.7-2.02.5-2.8-2.3
Length with tail1.45.29.1-2.53.0-2.2-2.9-0.9-1.51.9-2.8-2.0
Length without tail0.20.52.0-1.40.8-0.5-0.90.2-0.1-0.3-0.6-0.2
Liver weight, left0.40.61.9-1.11.4-0.7-1.0-0.0-0.30.1-0.9-0.5
Liver weight, right0.20.41.3-0.00.4-0.4-0.1-0.7-0.5-1.01.1-0.2
Parametrial fat weight1.22.44.8-2.20.2-2.1-1.4-1.9-1.9-0.1-0.8-1.7
Retroperitoneal fat weight2.27.311.6-2.71.9-3.0-3.2-2.8-2.42.3-2.4-3.4
Intraocular pressure0.71.04.20.00.1-0.3-0.6-1.1-1.42.1-1.0-0.6
Extensor digitorum longus weight0.93.517.50.2-4.20.61.7-2.5-1.9-0.60.70.4
Soleus weight0.20.51.50.91.20.00.20.80.50.9-0.30.1
Tibialis anterior weight0.62.04.7-0.9-0.6-1.3-0.6-2.2-1.91.8-1.1-1.7
Tibia length0.20.52.41.01.60.10.10.80.5-0.00.70.2
Number of licking bursts0.10.10.50.10.30.20.10.70.6-0.50.10.2
Food consumed during 24 hour testing period2.93.55.4-1.31.3-1.6-2.0-1.8-1.82.3-2.3-2.2
Times rat made contact with spout0.40.50.9-0.80.8-0.5-0.9-0.4-0.40.5-1.0-0.6
Mean time between licks in bursts0.30.41.0-0.60.2-0.6-0.5-0.9-1.00.1-0.3-0.6
Mean num. licks in bursts0.60.71.6-0.5-0.0-0.6-0.6-1.2-1.21.0-0.8-0.7
Std. dev. time between licks in bursts0.10.20.6-0.2-0.50.1-0.1-0.8-0.60.4-0.1-0.2
Water consumed over 24 hours0.30.40.9-0.10.6-0.7-0.7-0.8-0.60.6-0.3-0.9
Indifference point 0 sec5.58.813.1-1.53.5-3.5-3.1-1.9-2.23.6-2.9-3.6
Indifference point AUC1.61.93.5-1.21.6-0.9-1.6-1.1-1.11.6-1.9-1.0
Indifference point function ln k0.50.82.11.40.00.11.00.90.9-0.31.40.1
Indifference point function log k0.50.82.11.40.00.11.00.90.9-0.31.40.1
Delay discounting total patch changes 0 sec5.38.612.2-1.73.5-3.3-3.1-1.9-2.33.5-3.0-3.4
Delay discounting total patch changes 12 sec6.08.013.9-2.42.9-2.9-3.2-1.9-2.33.0-3.7-2.8
Delay discounting total patch changes 18 sec2.93.97.4-1.12.4-1.5-2.3-1.1-1.22.7-2.6-1.8
Delay discounting total patch changes 24 sec4.96.210.1-1.43.2-2.6-2.6-1.7-2.02.8-2.8-2.7
Delay discounting total patch changes 6 sec3.85.78.6-1.52.9-2.9-2.7-1.4-1.62.6-2.4-2.8
Delay discounting time to switch 0 sec0.50.82.30.2-1.51.10.70.50.5-0.90.61.0
Delay discounting water rate 0 sec2.54.06.3-1.32.2-2.5-2.1-1.9-1.82.0-1.4-2.5
Delay discounting water rate 12 sec0.50.83.41.30.2-0.10.70.30.7-0.91.8-0.0
Delay discounting water rate 18 sec0.40.61.50.91.1-0.80.10.50.5-0.51.2-0.6
Delay discounting water rate 24 sec0.20.31.00.60.3-0.00.20.70.5-0.71.00.2
Delay discounting water rate 6 sec0.10.20.80.70.3-0.20.3-0.1-0.1-0.20.9-0.4
Locomotor activity1.21.96.81.32.6-0.7-0.71.11.11.9-0.2-1.2
Locomotor testing distance1.52.48.11.32.6-0.6-0.81.00.82.9-1.1-1.3
Locomotor testing rearing0.91.45.20.41.40.1-0.90.91.22.3-1.3-0.8
Light reinforcement 10.71.23.90.90.7-0.9-0.1-0.9-1.22.0-1.0-1.3
Light reinforcement 20.81.02.6-0.10.5-0.8-0.5-1.2-1.61.5-0.8-0.8
Reaction time number correct0.50.81.41.1-0.40.31.10.70.4-1.21.20.8
Reaction time mean minus median0.30.42.30.1-1.50.40.5-0.4-0.2-0.50.40.3
Reaction time mean minus median AUC0.50.61.21.0-1.00.21.00.20.2-1.01.10.4
Reaction time num false alarms2.12.99.5-0.93.1-1.2-1.70.3-0.22.2-2.1-1.2
Reaction time num false alarms AUC2.33.29.3-1.33.0-1.5-1.90.0-0.52.1-2.2-1.6
Reaction time trials correct on left0.50.81.41.1-0.40.31.10.70.4-1.21.20.8
Reaction time trials on left0.50.71.41.0-0.40.31.10.50.3-1.21.20.7
Reaction time mean0.60.81.50.7-1.10.70.90.70.7-1.21.00.8
Reaction time mean AUC0.91.21.80.9-1.40.91.10.91.0-1.31.11.0
Median of all reaction times0.50.71.30.7-0.80.60.80.90.9-1.11.00.7
Reaction time omissions0.50.61.5-0.9-0.6-0.9-0.7-1.2-1.2-0.2-0.1-0.6
Reaction time false alarm rate2.13.07.0-1.52.7-1.1-2.0-0.0-0.32.2-2.3-1.4
Reaction time premature initiation rate1.11.53.7-0.01.2-1.5-0.8-0.8-0.91.9-1.2-1.6
Reaction time premature initiations0.50.71.30.40.9-1.2-0.2-0.5-0.71.1-0.6-1.1
Std. dev. reaction times0.30.52.1-0.3-1.50.20.4-0.3-0.1-1.00.60.3
Reaction time trials completed0.50.71.41.0-0.40.31.10.50.3-1.21.20.7
Reaction time trials AUC0.50.71.60.9-0.50.21.00.50.3-1.31.20.6
Social response proportion0.20.20.50.7-0.30.10.50.30.3-0.40.70.1
Social responses0.40.51.20.81.1-0.5-0.20.70.70.8-0.0-0.9
Social time0.40.51.00.3-0.91.00.60.60.4-0.60.31.0
Conditioned locomotion0.30.40.9-0.50.1-0.5-0.5-0.6-0.80.9-0.9-0.6
Cocaine response after cond. corrected0.70.83.10.2-0.90.60.90.40.3-1.81.10.9
Cocaine response after cond. not corrected2.12.35.70.8-0.81.31.41.71.6-2.41.51.6
Cocaine response before conditioning1.01.23.61.10.60.90.71.91.8-0.50.50.9
Saline control response1.11.46.50.10.8-0.4-0.6-0.3-0.42.5-1.9-1.1
Condit. Reinf. active minus inactive responses3.13.915.0-0.83.9-1.6-2.10.80.12.1-2.3-1.5
Condit. Reinf. active-inactive response ratio1.01.03.5-0.61.9-0.7-0.90.90.40.8-1.5-0.6
Condit. Reinf. active responses4.56.316.5-1.34.1-2.4-2.7-0.1-0.73.1-3.1-2.4
Condit. Reinf. inactive responses3.64.59.0-0.72.7-2.3-2.2-1.0-1.23.0-2.1-2.4
Condit. Reinf. lever presses1.92.66.80.12.6-1.5-1.40.40.22.4-1.7-1.8
Condit. Reinf. lever reinforcers received3.95.413.6-1.23.7-2.3-2.5-0.2-0.82.8-2.9-2.3
Pavlov. Cond. lever latency0.40.52.1-0.4-1.50.30.3-0.9-0.6-0.80.70.3
Pavlov. Cond. magazine entry latency3.23.65.41.5-1.12.31.82.02.0-2.21.72.3
Pavlov. Cond. change in total contacts0.30.51.50.11.20.3-0.31.10.70.5-0.70.3
Pavlov. Cond. index score0.60.82.40.90.70.80.41.51.4-0.30.10.7
Pavlov. Cond. latency score0.91.13.21.00.61.10.61.81.6-0.50.31.0
Pavlov. Cond. lever contacts0.30.51.60.41.3-0.4-0.40.50.31.0-0.7-0.6
Pavlov. Cond. magazine entry number4.04.96.8-2.01.2-2.6-2.1-2.3-2.42.3-2.1-2.6
Pavlov. Cond. intertrial magazine entries12.916.720.2-4.12.8-4.1-4.5-3.9-4.24.2-4.3-4.3
Pavlov. Cond. lever-magazine prob. diff.0.60.82.40.90.60.90.51.61.4-0.40.20.8
Pavlov. Cond. response bias0.20.20.80.40.90.1-0.00.70.60.1-0.1-0.1
Conditioned reinforcement - actives0.30.31.0-0.10.5-0.2-0.40.0-0.31.0-0.9-0.4
Conditioned reinforcement - inactives2.02.34.7-1.21.8-1.5-2.2-1.1-1.11.6-1.4-1.5
Conditioned locomotion2.53.04.5-1.21.6-1.9-1.7-1.3-1.52.1-2.1-1.9
Intermittent access intake day 1-15 change0.30.31.5-1.2-0.6-0.2-0.2-0.4-0.2-0.1-0.3-0.2
Intermittent access intake escalation0.20.20.8-0.9-0.8-0.10.2-0.3-0.0-0.20.0-0.0
Intermittent access intake escalation 20.80.83.2-1.8-0.3-0.8-0.8-1.0-0.70.2-0.8-0.9
Intermitt. access day 1 inactive lever presses2.93.19.8-0.63.1-1.3-2.20.3-0.22.2-1.9-1.6
Intermitt. access day 15 inactive lever presses1.31.43.3-0.90.7-1.0-1.4-1.0-0.91.8-1.1-1.5
Intermitt. access escalation Index5.04.47.11.9-1.12.12.12.12.2-2.72.22.2
Intermittent access day 1 total infusions0.91.02.4-0.11.5-1.3-1.0-0.3-0.71.3-0.8-1.2
Intermittent access day 15 total infusions0.50.61.2-0.70.4-1.0-0.6-0.6-0.70.8-0.6-1.1
Intermittent access terminal intake (last 3 days)2.42.63.7-1.81.3-1.9-1.8-1.3-1.41.5-1.5-1.9
Intermittent access total infusions2.83.14.5-1.22.1-2.1-1.9-0.9-1.22.0-1.7-2.1
Intermittent access day 1 locomotion3.53.65.8-0.92.4-2.2-2.0-0.9-1.42.4-1.9-2.2
Intermittent access day 15 total locomotion5.55.88.5-2.02.6-2.9-2.6-1.4-1.72.6-2.6-2.9
Intermittent access total locomotion9.110.315.4-2.13.5-3.8-3.4-2.0-2.33.8-3.2-3.9
Intermittent access standard deviation1.51.63.2-1.10.8-1.2-1.3-1.2-1.11.8-1.3-1.4
Cocaine induced anxiety0.10.20.50.6-0.20.20.60.30.3-0.20.70.0
Post-drug Anxiety0.50.51.20.4-1.10.81.00.0-0.0-0.80.70.8
Baseline Anxiety0.70.81.70.5-1.31.01.1-0.1-0.0-1.10.71.1
Lifetime Intake3.43.86.5-0.92.5-2.2-2.1-0.9-1.22.5-2.0-2.3
Incentive Sensitization - Responses1.71.72.9-1.71.3-1.1-1.6-0.8-1.31.2-1.6-0.9
Incentive Sensitization - Breakpoint1.51.52.8-1.71.3-1.0-1.6-0.6-1.21.0-1.5-0.8
Progressive ratio test 1 active lever presses3.73.88.6-0.92.9-1.8-2.2-0.5-1.02.5-2.2-2.1
Progressive ratio test 1 breakpoint4.74.99.6-1.03.1-2.0-2.4-0.7-1.33.1-2.5-2.4
Progressive ratio test 1 inactive lever presses4.34.612.6-0.53.6-2.0-2.5-0.2-0.82.8-2.0-2.3
Progressive ratio test 2 active lever presses3.63.95.6-1.62.3-2.0-2.1-1.0-1.72.4-2.3-1.9
Progressive ratio test 2 breakpoint3.84.26.0-1.82.3-2.1-2.3-1.0-1.72.4-2.4-2.0
Progressive ratio test 2 inactive lever presses4.85.57.8-1.62.6-2.8-2.6-1.5-2.12.7-2.3-2.7
Total sessions with >9 infusions0.60.72.01.21.4-0.5-0.20.3-0.21.4-0.3-0.6
Short access day 1 total inactive lever presses1.01.13.3-0.11.8-1.1-1.4-0.2-0.31.3-1.0-1.0
Short access day 10 total inactive lever presses1.11.22.4-0.70.8-1.5-1.1-1.0-1.01.1-0.8-1.5
Short access day 1 total infusions1.71.85.01.02.2-1.1-0.80.3-0.32.2-0.9-1.4
Short access day 10 total infusions7.17.811.9-1.83.1-3.0-3.1-1.9-2.13.5-2.8-3.3
Short access total infusions3.43.78.8-0.13.0-1.8-1.9-0.2-0.63.0-1.8-2.2
Short access day 1 locomotion4.95.112.1-0.32.5-2.4-1.9-1.5-1.93.5-2.2-2.7
Short access day 10 total locomotion10.711.720.5-2.53.3-3.5-3.6-2.3-2.64.5-4.0-3.8
Short access total locomotion6.36.415.8-0.72.9-2.5-2.5-1.4-1.74.0-2.7-2.9
Compulsive drug intake1.91.93.61.3-0.41.21.01.41.6-1.91.71.1
One hour access (0.3 mA shock)0.70.81.8-0.71.3-0.7-1.20.0-0.10.9-1.0-1.0
One hour access (shock baseline)1.72.03.7-1.31.1-1.3-1.4-1.0-1.21.9-1.8-1.4
Number of responses in last shaping day0.60.61.80.21.1-0.9-0.40.2-0.11.3-0.8-1.0
Context. condit. distance diff. score0.00.00.20.10.20.20.20.20.4-0.00.20.1
Locomotion velocity, session 10.40.41.0-0.51.0-0.4-1.0-0.4-0.50.7-0.6-0.4
Locomotion distance, session 10.40.51.1-0.11.0-0.6-0.9-0.7-0.70.7-0.2-0.6
Locomotion velocity, session 20.50.61.40.01.20.4-0.81.21.10.6-0.60.1
Locomotion distance, session 20.30.41.10.71.00.5-0.30.80.80.30.10.3
Locomotion velocity, session 31.01.12.21.50.41.40.81.21.1-0.00.91.3
Locomotion distance, session 30.40.40.80.30.80.6-0.10.90.7-0.20.50.8
Stereotopy head waving bouts, day 30.40.41.00.6-1.00.71.0-0.0-0.1-0.50.60.8
Stereotopy head waving duration, day 30.40.41.10.9-0.60.71.10.30.1-0.40.40.8
Locomotion velocity, session 70.20.20.80.2-0.50.40.2-0.00.4-0.60.90.2
Locomotion distance, session 70.00.00.10.20.2-0.2-0.3-0.2-0.10.1-0.1-0.2
Stereotopy head waving bouts, day 71.41.53.01.5-0.41.71.31.41.4-0.50.71.5
Stereotopy head waving duration, day 73.84.67.52.1-1.22.72.32.52.3-1.51.42.6
Locomotion velocity, session 80.30.31.0-1.00.9-0.2-1.00.00.10.2-0.5-0.3
Locomotion distance, session 80.10.21.00.11.00.0-0.30.40.50.5-0.1-0.1
Degree of sensitization distance0.80.81.4-0.8-0.1-1.0-0.7-1.2-1.20.4-1.0-1.1
Degree of sensitization stereotypy2.62.95.02.1-0.22.21.52.22.2-0.51.01.8
Condit. Reinf. active minus inactive responses1.61.73.8-0.31.9-1.4-1.00.4-0.12.0-1.8-1.3
Condit. Reinf. active-inactive response ratio0.40.41.2-0.10.9-0.5-0.30.70.40.8-1.1-0.3
Condit. Reinf. active responses2.32.85.7-0.62.3-1.9-1.40.1-0.62.4-2.2-1.9
Condit. Reinf. inactive responses1.51.83.0-0.91.6-1.7-1.4-0.8-1.11.4-1.1-1.7
Incentive salience index mean1.21.53.5-0.31.9-1.1-0.90.70.31.8-1.6-1.2
Condit. Reinf. lever presses0.30.41.30.50.60.10.31.20.90.9-0.4-0.3
Time in familiar zone, hab. session 11.01.01.6-1.30.2-1.1-1.1-1.0-1.10.6-1.1-0.9
Time in novel zone, hab. session 10.90.91.81.3-0.50.91.10.61.0-0.71.30.7
Total zone transitions, hab. session 10.50.71.70.11.3-1.0-0.9-0.4-0.21.2-0.2-1.3
Total locomotion distance, hab. session 11.42.03.9-0.32.0-1.7-1.6-0.8-0.61.8-0.9-2.0
Locomotion velocity, hab. session 11.52.14.0-0.62.0-1.7-1.7-0.8-0.81.8-1.1-1.9
Time in familiar zone, hab. session 20.90.92.2-1.11.2-0.5-1.2-0.1-0.11.0-1.5-0.6
Time in novel zone, hab. session 20.70.72.60.5-1.10.10.7-0.5-0.3-1.21.60.3
Total zone transitions, hab. session 20.20.20.80.20.80.0-0.50.00.20.9-0.1-0.4
Total locomotion distance, hab. session 21.21.62.7-0.71.1-1.3-1.4-1.4-1.21.7-0.8-1.6
Locomotion velocity, hab. session 21.01.42.2-0.71.0-1.2-1.3-1.3-1.21.5-0.8-1.4
Novel to familiar place preference ratio1.11.13.3-0.81.0-1.8-1.0-0.7-0.70.7-0.5-1.7
Novelty place preference0.70.72.2-0.60.8-1.5-0.7-0.4-0.30.5-0.2-1.4
Time in novel zone, NPP test0.50.51.7-0.40.9-1.3-0.6-0.2-0.10.3-0.0-1.2
Total zone transitions, NPP test0.30.41.80.71.3-0.1-0.40.0-0.11.1-0.1-0.4
Total locomotion distance, NPP test1.01.42.3-0.71.5-1.1-1.5-1.0-0.91.4-0.7-1.4
Locomotion velocity, NPP test1.11.53.0-0.41.2-1.1-1.3-1.4-1.41.7-0.9-1.3
Pavlov. Cond. lever latency1.11.44.7-0.2-2.20.20.7-0.9-0.7-1.91.20.8
Pavlov. Cond. magazine entry latency1.82.35.6-0.62.4-1.1-1.50.5-0.02.3-2.0-1.4
Pavlov. Cond. change in total contacts1.61.75.6-0.12.0-0.7-0.90.60.32.4-1.7-1.1
Pavlov. Cond. index score1.72.16.5-0.32.5-0.8-1.20.70.32.3-1.8-1.2
Pavlov. Cond. latency score1.51.96.2-0.12.5-0.5-1.10.90.52.2-1.6-1.0
Pavlov. Cond. lever contacts0.81.02.90.21.50.1-0.50.90.81.7-1.3-0.5
Pavlov. Cond. magazine entry number1.21.64.00.3-2.00.91.0-0.6-0.1-2.01.61.0
Pavlov. Cond. intertrial magazine entries2.32.74.7-0.41.7-2.0-1.4-1.2-1.72.2-1.8-1.9
Pavlov. Cond. lever-magazine prob. diff.1.51.95.8-0.22.4-0.7-1.10.80.32.2-1.7-1.0
Pavlov. Cond. response bias1.41.84.9-0.12.2-0.7-1.00.90.32.2-1.7-1.0
Bone: apparent density0.61.02.1-1.21.4-1.0-1.3-0.8-0.90.5-0.6-0.9
Bone surface3.35.912.9-2.93.6-2.4-3.4-0.9-1.21.3-2.3-2.2
Bone volume2.94.910.3-2.43.2-2.4-2.9-1.1-1.41.5-2.0-2.1
Bone: connectivity density1.01.63.2-1.61.8-1.2-1.8-0.7-0.90.5-1.1-1.0
Bone: cortical apparent density1.52.05.41.9-1.60.81.9-0.30.2-1.02.30.8
Bone: cortical area2.53.710.2-0.63.2-2.1-2.0-1.0-0.92.5-1.0-2.3
Bone: cortical porosity2.32.56.3-1.02.5-1.0-1.71.00.71.9-2.0-1.3
Bone: cortical porosity1.71.86.4-0.32.5-1.1-1.31.00.61.7-1.3-1.2
Bone: cortical thickness1.62.710.03.2-0.21.01.90.20.80.03.00.5
Bone: cortical thickness1.51.75.42.3-0.10.61.40.61.4-0.42.30.3
Bone: cortical tissue density1.52.05.11.9-1.70.81.9-0.20.2-1.02.30.8
Bone: elastic displacement1.61.84.41.7-0.50.91.51.21.4-1.12.11.0
Bone: elastic work0.30.41.00.10.7-0.8-0.4-0.5-0.10.50.7-1.0
Bone: endosteal estimation9.921.435.2-5.25.5-4.9-5.9-1.5-2.23.9-5.7-4.7
Bone: endosteal perimeter10.922.436.4-5.35.9-4.7-6.0-1.7-2.54.1-5.9-4.4
Bone: final force1.42.47.7-0.82.8-2.1-1.7-0.6-0.40.9-0.5-2.0
Bone: final moment1.52.47.8-0.92.8-2.1-1.7-0.6-0.40.9-0.5-2.1
Bone: marrow area9.620.534.0-5.25.3-4.8-5.8-1.5-2.13.7-5.5-4.6
Bone: maximum diameter3.97.216.8-2.44.1-3.0-3.3-0.8-1.32.5-2.6-2.7
Bone: maximum force2.95.111.6-1.23.4-2.9-2.5-1.4-1.52.1-1.4-2.8
Bone: maximum moment3.05.111.3-1.33.4-3.0-2.5-1.4-1.42.0-1.3-2.9
Bone: minimum diameter10.319.028.2-4.25.3-4.7-5.3-2.3-2.84.4-4.7-4.6
Bone: periosteal estimation8.016.429.6-3.75.4-4.6-5.0-1.6-2.03.9-4.1-4.5
Bone: periosteal perimeter3.55.716.9-2.04.1-2.5-2.9-0.3-0.72.1-2.4-2.3
Bone: post-yield work1.92.64.8-1.82.2-1.5-2.2-0.7-0.81.3-1.7-1.5
Bone: stiffness1.52.47.7-0.82.8-1.8-1.8-0.4-0.61.2-1.2-1.7
Bone: tissue strength1.01.01.81.3-0.11.10.91.00.8-0.91.31.1
Bone: trabecular number1.01.54.4-1.22.1-1.1-1.7-0.5-0.90.8-1.1-0.8
Bone: trabecular spacing0.40.51.20.6-1.10.90.90.60.7-0.40.20.7
Bone: trabecular thickness1.82.23.0-1.41.4-1.7-1.6-1.5-1.71.2-1.0-1.5
Bone: trabecular tissue density0.30.52.20.8-0.0-0.20.5-0.5-0.4-0.71.50.1
Breakpoint value in progressive ratio session0.40.40.90.20.70.7-0.31.00.70.8-0.70.5
Distance traveled before self-admin1.92.04.10.9-0.41.71.21.81.5-1.51.02.0
Distance traveled after self-admin1.61.74.51.00.31.70.82.11.8-0.8-0.11.6
Delta time in closed arm before/after self-admin0.10.10.4-0.30.20.2-0.20.40.5-0.70.00.5
Delta time in open arm before/after self-admin0.40.41.30.5-1.20.50.9-0.4-0.60.20.20.5
Diff in mean of infusions in LGA sessions0.80.91.81.3-1.01.11.00.40.7-0.31.20.7
Extinction: sum of active levers before priming0.30.30.8-0.10.3-0.5-0.3-0.4-0.60.9-0.8-0.5
Active lever presses in extinction session 61.41.32.6-0.61.1-1.2-1.2-0.5-0.61.6-1.6-1.3
Delta distance traveled before/after self-admin0.30.41.21.10.30.70.20.70.90.5-0.20.2
Delta ambulatory time before/after self-admin0.20.20.80.30.5-0.0-0.30.00.10.7-0.9-0.3
Time in closed arm before self-admin0.80.92.51.60.00.70.81.11.5-0.31.00.5
Time in closed arm after self-admin1.01.12.60.5-0.10.80.31.21.6-1.51.11.0
Time in open arm before self-admin0.91.02.20.3-1.01.20.90.70.8-1.51.11.1
Time in open arm after self-admin0.30.31.2-0.3-0.80.10.3-0.7-1.10.5-0.50.1
Sum of active levers in priming session hrs 5-60.90.92.01.4-0.50.71.31.31.0-0.10.30.6
Time to tail flick, vehicle, before self-admin0.80.83.4-0.4-0.40.70.50.70.5-1.80.91.2
Time to tail flick, vehicle, after self-admin0.50.61.9-1.10.3-0.6-0.6-0.8-1.40.2-0.7-0.2
Time to tail flick, test, before self-admin0.80.72.9-0.2-1.70.20.8-0.00.2-1.50.70.7
Time to tail flick, test, after self-admin0.10.10.30.4-0.2-0.50.60.2-0.0-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA2.72.63.7-1.50.7-1.7-1.7-1.8-1.91.6-1.7-1.7
Delta time to tail flick, test, before/after SA0.10.10.50.20.7-0.50.10.40.00.2-0.1-0.4
Ambulatory time before self-admin1.31.32.70.6-0.11.50.81.61.3-1.20.81.6
Ambulatory time after self-admin0.60.71.90.70.70.90.21.41.1-0.1-0.60.8
Total heroin consumption0.40.51.80.41.10.10.11.40.90.4-0.40.3
Area under the delay curve0.10.10.70.00.2-0.40.0-0.3-0.80.2-0.10.1
Delay disc. indifference point, 0s delay0.40.40.80.4-0.90.50.80.2-0.1-0.70.50.9
Delay disc. indifference point, 16s delay0.20.20.90.20.3-0.60.1-0.5-1.00.5-0.2-0.2
Delay disc. indifference point, 2s delay0.70.81.7-0.91.0-1.3-0.7-0.6-1.2-0.1-0.7-0.8
Delay disc. indifference point, 24s delay2.22.23.2-0.61.5-1.7-1.2-1.4-1.81.8-1.2-1.6
Delay disc. indifference point, 4s delay0.80.81.90.8-0.60.91.10.90.6-1.00.81.4
Delay disc. indifference point, 8s delay0.20.20.40.4-0.40.20.5-0.3-0.7-0.20.40.5
Delay discount exponential model param0.20.20.90.3-0.40.60.20.40.9-0.30.30.1
Delay discount hyperbolic model param0.20.20.80.2-0.30.60.10.40.9-0.20.30.1
Fecal boli incidents, locomotor time 10.20.20.50.1-0.70.40.50.3-0.1-0.60.00.7
Change in fecal boli incidents, locomotor task0.50.41.6-0.2-0.3-0.6-0.2-1.3-1.10.5-0.2-0.6
Time >=10cm from walls, locomotor time 12.42.44.01.0-0.51.51.21.82.0-2.01.71.6
Bouts of movement, locomotor time 10.30.41.40.1-1.2-0.50.3-0.9-0.60.10.6-0.4
Total resting periods, locomotor time 10.40.51.7-0.1-1.3-0.50.3-1.1-0.8-0.10.6-0.3
Rest time, locomotor task time 10.40.51.9-0.0-1.40.40.7-0.1-0.1-1.00.40.7
Distance moved, locomotor task time 10.60.61.0-0.70.9-0.5-1.0-0.7-0.60.9-0.6-0.8
Vertical activity count, locomotor time 10.20.20.9-0.30.9-0.2-0.7-0.2-0.10.4-0.3-0.5
Time >=10cm from walls, locomotor time 20.70.71.60.1-0.71.10.30.81.3-1.20.80.8
Bouts of movement, locomotor time 20.20.21.10.3-1.00.10.4-0.7-0.40.30.20.1
Total resting periods, locomotor time 20.30.31.30.5-1.20.30.7-0.4-0.20.10.40.4
Rest time, locomotor task time 23.84.47.91.3-2.82.42.40.90.6-2.61.92.7
Distance moved, locomotor task time 20.40.51.2-0.60.7-0.3-1.1-0.40.21.0-0.6-0.9
Vertical activity count, locomotor time 22.22.44.8-1.01.7-1.4-1.8-0.8-0.42.2-1.5-2.1
Weight adjusted by age0.60.71.40.9-0.90.91.20.60.3-0.80.71.1
Seeking ratio, delayed vs. immediate footshock0.30.31.1-0.0-0.0-0.5-0.1-0.7-0.61.0-0.4-0.5
Locomotion in novel chamber0.30.41.30.20.50.30.11.10.8-0.90.50.6
Locomotion in novel chamber post-restriction2.12.44.5-2.11.8-2.1-1.8-0.8-1.20.3-1.2-1.7
Progressive ratio0.30.41.8-0.5-0.40.50.00.0-0.2-1.30.10.8
Food seeking constrained by brief footshock1.92.35.4-2.21.4-0.7-2.2-0.6-0.61.3-2.3-1.2
Seeking ratio, punishment vs. effort1.21.43.9-0.81.2-0.9-1.3-0.3-0.12.0-1.5-1.4
Run reversals in cocaine runway, females0.80.83.80.1-1.90.60.4-1.3-0.7-0.50.80.1
Run reversals in cocaine runway, males0.10.10.20.2-0.3-0.20.40.1-0.1-0.40.40.2
Latency to leave start box in cocaine runway0.50.61.10.7-0.30.90.70.91.0-0.60.80.7
Latency to leave start box in cocaine runway, F1.31.52.81.50.11.31.11.71.7-0.60.91.1
Latency to leave start box in cocaine runway, M0.20.20.7-0.7-0.9-0.1-0.1-0.5-0.2-0.50.2-0.3
Cd content in liver2.22.55.30.8-2.31.22.00.60.9-2.31.61.4
Co content in liver0.70.81.20.2-1.10.91.01.01.1-0.90.50.9
Cu content in liver0.20.30.7-0.4-0.4-0.5-0.3-0.6-0.80.5-0.5-0.4
Fe content in liver0.20.30.80.90.4-0.10.30.80.70.30.2-0.0
K content in liver0.40.41.6-0.81.3-0.3-0.90.60.10.1-0.7-0.1
Mg content in liver0.20.20.9-0.9-0.2-0.3-0.3-0.1-0.3-0.5-0.2-0.1
Mn content in liver0.30.31.50.11.2-0.4-0.10.80.4-0.40.2-0.1
Na content in liver0.80.93.00.61.30.80.11.71.10.5-0.50.7
Rb content in liver1.62.03.71.2-0.81.01.31.41.4-1.81.91.4
Se content in liver1.31.63.81.3-0.71.71.31.20.8-1.00.91.9
Sr content in liver0.20.20.8-0.40.9-0.3-0.6-0.2-0.10.2-0.1-0.5
Zn content in liver0.30.30.80.10.70.30.10.70.2-0.80.50.9