Hub : Genes

Smtnl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000015157	0.03	0.03	3.6e-03	0.02	0.02	0.02	0.02	2.2e-03	3.2e-03	6.4e-03	3.3e-03
2	BLA	gene expression	ENSRNOG00000015157	0.07	0.06	6.9e-03	0.01	0.02	0.02	0.01	1.2e-01	4.0e-02	4.3e-02	7.6e-02
3	Brain	gene expression	ENSRNOG00000015157	0.15	0.09	1.6e-12	0.13	0.14	0.12	0.13	4.5e-12	1.4e-12	1.9e-11	3.3e-12
4	Eye	gene expression	ENSRNOG00000015157	0.49	0.35	2.2e-03	0.17	0.15	0.22	0.16	1.4e-03	2.4e-03	2.6e-04	1.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
BMI with tail	0.2	0.5	1.0	-0.5	1.0	0.5	-0.9
BMI without tail	0.6	1.2	1.7	-0.9	1.3	0.8	-1.3
Body weight	1.8	7.7	9.1	-3.0	2.6	2.9	-2.6
Epididymis fat weight	2.3	5.5	10.4	-1.4	3.2	1.7	-2.5
Glucose	3.4	5.2	7.5	2.7	-1.8	-2.3	2.1
Heart weight	0.3	0.4	1.2	-0.1	1.1	0.3	-0.6
Left kidney weight	0.0	0.1	0.4	-0.0	-0.1	-0.6	-0.4
Right kidney weight	0.0	0.1	0.2	-0.1	-0.2	-0.5	-0.4
Tail length	3.4	10.4	12.0	-3.5	3.1	3.3	-3.0
Length with tail	2.2	8.1	11.3	-3.4	2.3	3.0	-2.6
Length without tail	1.8	3.8	5.0	-2.2	1.7	2.0	-1.8
Liver weight, left	0.8	1.3	2.1	-1.4	0.7	1.2	-1.0
Liver weight, right	1.4	2.2	3.1	-1.5	1.5	1.1	-1.8
Parametrial fat weight	9.1	17.8	29.2	-3.1	5.4	3.2	-4.7
Retroperitoneal fat weight	0.1	0.2	0.5	0.6	0.1	-0.7	-0.1
Intraocular pressure	1.3	1.8	4.4	2.1	-0.1	-1.4	0.9
Extensor digitorum longus weight	1.5	6.1	11.2	-1.2	3.3	0.7	-3.3
Soleus weight	4.7	13.7	16.0	-3.9	3.7	3.2	-4.0
Tibialis anterior weight	2.7	9.1	15.4	-2.2	3.9	2.1	-3.5
Tibia length	0.7	2.1	3.9	-2.0	0.6	1.9	-0.7
Number of licking bursts	0.4	0.4	0.8	0.7	-0.6	-0.4	0.9
Food consumed during 24 hour testing period	0.4	0.5	1.3	-1.1	-0.1	0.7	-0.5
Times rat made contact with spout	0.3	0.4	0.9	0.1	-0.7	0.3	0.9
Mean time between licks in bursts	1.8	2.6	3.9	-1.5	1.7	1.0	-2.0
Mean num. licks in bursts	0.1	0.2	0.3	-0.5	0.2	0.5	-0.2
Std. dev. time between licks in bursts	0.5	0.7	1.0	-0.7	0.9	0.5	-1.0
Water consumed over 24 hours	0.8	0.9	1.6	-1.3	-0.9	1.0	0.3
Indifference point 0 sec	0.6	1.0	2.7	0.4	-0.8	0.6	1.6
Indifference point AUC	0.8	0.9	2.0	1.2	-0.1	-1.4	0.1
Indifference point function ln k	1.0	1.4	2.1	-1.4	-1.1	1.4	0.7
Indifference point function log k	1.0	1.4	2.1	-1.4	-1.1	1.4	0.7
Delay discounting total patch changes 0 sec	0.5	0.8	2.4	0.5	-0.7	0.5	1.5
Delay discounting total patch changes 12 sec	0.4	0.6	1.6	1.3	0.4	-0.6	0.5
Delay discounting total patch changes 18 sec	0.2	0.2	0.6	0.8	0.3	-0.2	0.4
Delay discounting total patch changes 24 sec	0.5	0.6	1.0	1.0	-0.3	-0.9	0.6
Delay discounting total patch changes 6 sec	0.9	1.4	3.3	1.8	0.0	-1.2	0.9
Delay discounting time to switch 0 sec	0.4	0.7	1.7	-0.1	1.3	0.2	-1.0
Delay discounting water rate 0 sec	0.3	0.5	1.1	0.3	-1.0	-0.4	0.8
Delay discounting water rate 12 sec	0.4	0.7	1.1	-0.6	1.0	0.8	-0.7
Delay discounting water rate 18 sec	1.0	1.3	2.2	-1.5	0.6	1.5	-0.7
Delay discounting water rate 24 sec	0.0	0.0	0.1	0.0	0.2	-0.1	-0.3
Delay discounting water rate 6 sec	0.1	0.1	0.2	-0.4	-0.4	-0.1	-0.2
Locomotor activity	0.2	0.3	0.8	0.1	0.9	0.2	-0.5
Locomotor testing distance	0.6	1.0	2.5	0.6	1.6	-0.3	-1.0
Locomotor testing rearing	0.6	0.9	1.5	1.1	1.2	-0.8	-0.6
Light reinforcement 1	0.3	0.5	1.3	0.6	1.1	-0.1	-0.5
Light reinforcement 2	0.1	0.1	0.3	0.5	-0.0	-0.5	0.1
Reaction time number correct	0.2	0.4	0.4	-0.6	0.6	0.6	-0.6
Reaction time mean minus median	1.9	2.5	4.3	1.9	-1.2	-1.0	2.1
Reaction time mean minus median AUC	0.8	1.1	1.8	1.3	-0.6	-0.6	1.3
Reaction time num false alarms	1.3	1.8	3.5	1.2	-1.3	-0.6	1.9
Reaction time num false alarms AUC	1.0	1.4	2.4	1.1	-1.2	-0.7	1.5
Reaction time trials correct on left	0.2	0.4	0.4	-0.6	0.6	0.6	-0.6
Reaction time trials on left	0.2	0.3	0.4	-0.6	0.5	0.5	-0.6
Reaction time mean	0.5	0.7	1.3	1.0	-0.7	-0.5	1.1
Reaction time mean AUC	1.1	1.5	2.2	1.3	-1.1	-0.8	1.5
Median of all reaction times	0.2	0.3	0.4	0.6	-0.5	-0.4	0.6
Reaction time omissions	0.1	0.2	0.5	0.7	0.3	-0.3	0.2
Reaction time false alarm rate	1.1	1.6	2.7	1.2	-1.2	-0.7	1.7
Reaction time premature initiation rate	0.3	0.4	0.8	-0.7	-0.4	0.9	0.4
Reaction time premature initiations	0.4	0.6	1.2	-1.0	-0.1	1.1	-0.0
Std. dev. reaction times	1.8	2.5	4.3	1.6	-1.5	-0.9	2.1
Reaction time trials completed	0.2	0.3	0.4	-0.6	0.5	0.5	-0.6
Reaction time trials AUC	0.2	0.3	0.3	-0.5	0.5	0.5	-0.6
Social response proportion	2.6	2.8	6.2	-1.8	1.1	2.5	-0.6
Social responses	1.5	1.9	3.9	-0.7	2.0	1.5	-1.0
Social time	1.4	1.9	3.1	-1.0	1.8	1.5	-1.1
Conditioned locomotion	1.1	1.3	1.6	1.1	-1.3	-1.0	1.2
Cocaine response after cond. corrected	0.3	0.3	0.8	-0.6	0.0	0.9	0.2
Cocaine response after cond. not corrected	0.3	0.3	0.8	-0.6	0.3	0.9	0.1
Cocaine response before conditioning	0.3	0.3	0.8	-0.2	0.9	0.2	-0.7
Saline control response	0.1	0.2	0.6	0.2	0.8	0.3	-0.2
Condit. Reinf. active minus inactive responses	0.2	0.2	0.6	-0.2	-0.0	0.7	0.5
Condit. Reinf. active-inactive response ratio	0.3	0.4	1.0	0.2	-0.4	0.5	1.0
Condit. Reinf. active responses	0.1	0.1	0.3	-0.3	0.0	0.6	0.1
Condit. Reinf. inactive responses	0.0	0.1	0.1	0.2	0.0	-0.4	-0.2
Condit. Reinf. lever presses	0.9	1.2	1.6	1.3	-1.0	-0.9	1.2
Condit. Reinf. lever reinforcers received	0.0	0.1	0.1	-0.0	-0.1	0.3	0.3
Pavlov. Cond. lever latency	2.3	3.1	4.2	-1.7	1.9	1.3	-2.1
Pavlov. Cond. magazine entry latency	0.5	0.6	1.1	0.5	-1.0	-0.4	1.0
Pavlov. Cond. change in total contacts	0.5	0.7	1.2	0.6	-1.1	-0.5	1.0
Pavlov. Cond. index score	2.0	2.6	2.8	1.7	-1.7	-1.5	1.7
Pavlov. Cond. latency score	2.5	3.1	3.3	1.8	-1.8	-1.7	1.8
Pavlov. Cond. lever contacts	1.0	1.4	1.7	1.2	-1.1	-0.9	1.3
Pavlov. Cond. magazine entry number	0.7	0.9	1.2	-0.8	1.1	0.7	-1.1
Pavlov. Cond. intertrial magazine entries	0.6	0.8	1.6	-0.5	1.3	0.7	-0.9
Pavlov. Cond. lever-magazine prob. diff.	2.0	2.6	2.9	1.6	-1.7	-1.4	1.7
Pavlov. Cond. response bias	1.1	1.5	2.0	1.2	-1.3	-0.9	1.4
Conditioned reinforcement - actives	0.6	0.6	1.1	-0.5	1.0	0.3	-1.1
Conditioned reinforcement - inactives	0.4	0.5	1.2	0.8	1.1	-0.1	-0.1
Conditioned locomotion	0.3	0.4	1.2	0.4	-0.2	-1.1	-0.4
Intermittent access intake day 1-15 change	1.6	1.6	3.1	1.8	-0.4	-1.6	0.8
Intermittent access intake escalation	1.4	1.4	2.7	1.5	-0.6	-1.6	0.6
Intermittent access intake escalation 2	2.0	2.0	3.1	1.5	-1.2	-1.8	1.0
Intermitt. access day 1 inactive lever presses	2.2	2.4	4.2	2.0	-0.9	-1.3	1.7
Intermitt. access day 15 inactive lever presses	0.2	0.3	0.7	0.5	-0.0	0.3	0.8
Intermitt. access escalation Index	1.9	1.7	2.3	-1.2	1.4	1.5	-1.0
Intermittent access day 1 total infusions	0.8	0.9	1.9	-0.3	1.4	0.3	-1.2
Intermittent access day 15 total infusions	0.9	1.1	1.6	1.0	0.9	-1.3	-0.9
Intermittent access terminal intake (last 3 days)	0.9	1.0	2.1	0.2	1.5	-0.3	-1.3
Intermittent access total infusions	0.6	0.7	1.3	0.2	1.0	-0.5	-1.2
Intermittent access day 1 locomotion	0.6	0.6	1.3	0.1	1.1	-0.2	-1.1
Intermittent access day 15 total locomotion	0.4	0.5	1.1	0.4	0.3	-1.0	-0.8
Intermittent access total locomotion	0.3	0.3	0.7	0.1	0.6	-0.4	-0.9
Intermittent access standard deviation	1.7	1.8	4.6	1.6	-0.1	-2.1	-0.3
Cocaine induced anxiety	0.9	1.1	1.9	0.6	-1.4	-0.4	1.4
Post-drug Anxiety	0.7	0.8	2.2	0.8	-0.5	0.2	1.5
Baseline Anxiety	0.2	0.2	0.7	0.4	0.8	0.2	0.0
Lifetime Intake	0.8	0.9	1.7	0.4	1.3	-0.5	-1.2
Incentive Sensitization - Responses	0.1	0.1	0.2	-0.1	0.4	0.1	-0.4
Incentive Sensitization - Breakpoint	0.1	0.1	0.1	-0.0	0.4	0.1	-0.3
Progressive ratio test 1 active lever presses	1.3	1.3	2.4	-0.9	1.3	0.6	-1.5
Progressive ratio test 1 breakpoint	1.8	1.9	2.9	-1.0	1.7	1.0	-1.6
Progressive ratio test 1 inactive lever presses	0.3	0.4	0.6	0.2	0.8	-0.3	-0.8
Progressive ratio test 2 active lever presses	0.5	0.5	1.0	-0.4	0.9	0.2	-1.0
Progressive ratio test 2 breakpoint	0.3	0.4	0.7	-0.4	0.8	0.3	-0.9
Progressive ratio test 2 inactive lever presses	0.5	0.6	1.3	0.9	1.1	-0.2	-0.3
Total sessions with >9 infusions	1.2	1.3	2.9	-0.7	1.4	0.2	-1.7
Short access day 1 total inactive lever presses	0.2	0.2	0.6	0.7	0.3	-0.1	0.5
Short access day 10 total inactive lever presses	0.0	0.0	0.0	-0.0	-0.1	0.1	0.2
Short access day 1 total infusions	0.9	0.9	1.6	1.3	0.5	-1.3	-0.3
Short access day 10 total infusions	0.4	0.4	1.1	0.3	1.0	-0.1	-0.7
Short access total infusions	0.8	0.9	1.2	1.1	1.1	-0.8	-0.6
Short access day 1 locomotion	0.6	0.6	1.5	1.2	0.1	-1.0	0.3
Short access day 10 total locomotion	0.3	0.3	0.7	0.7	0.1	-0.9	-0.2
Short access total locomotion	0.2	0.3	0.6	0.5	0.2	-0.8	-0.4
Compulsive drug intake	0.2	0.2	0.6	-0.2	-0.2	0.8	0.5
One hour access (0.3 mA shock)	0.3	0.4	1.0	0.3	1.0	-0.2	-0.7
One hour access (shock baseline)	0.6	0.7	1.8	-0.1	1.0	-0.4	-1.3
Number of responses in last shaping day	1.0	1.0	2.0	1.4	-0.3	-1.1	0.8
Context. condit. distance diff. score	1.1	1.3	2.1	-0.9	1.5	1.0	-1.2
Locomotion velocity, session 1	4.0	4.3	4.7	-2.2	2.1	1.9	-2.1
Locomotion distance, session 1	0.5	0.6	1.1	-0.6	1.0	0.3	-1.0
Locomotion velocity, session 2	0.5	0.6	1.2	-1.1	0.3	1.0	-0.5
Locomotion distance, session 2	0.5	0.8	0.9	-0.9	0.9	0.9	-0.7
Locomotion velocity, session 3	0.9	1.0	2.9	0.2	-1.7	-0.8	0.8
Locomotion distance, session 3	0.0	0.0	0.1	-0.0	-0.3	-0.1	0.1
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	-0.7	0.1	0.3	-0.5
Stereotopy head waving duration, day 3	0.5	0.7	1.7	0.7	-0.7	-1.3	0.1
Locomotion velocity, session 7	0.1	0.1	0.2	0.4	0.1	-0.1	0.2
Locomotion distance, session 7	0.2	0.2	0.4	0.6	0.0	0.1	0.7
Stereotopy head waving bouts, day 7	0.9	1.0	1.6	-0.8	1.2	0.6	-1.3
Stereotopy head waving duration, day 7	1.3	1.6	2.4	-1.1	1.4	0.8	-1.5
Locomotion velocity, session 8	1.3	1.5	3.2	-1.2	1.1	0.5	-1.8
Locomotion distance, session 8	2.5	3.8	4.4	-1.9	2.1	1.8	-2.0
Degree of sensitization distance	0.2	0.2	0.7	0.4	0.8	0.3	-0.0
Degree of sensitization stereotypy	1.6	1.8	2.4	-1.2	1.6	1.2	-1.3
Condit. Reinf. active minus inactive responses	0.4	0.5	1.3	0.2	-0.3	0.7	1.1
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.0	0.2	-0.3	0.5	1.0
Condit. Reinf. active responses	0.3	0.4	1.1	0.2	-0.1	0.7	1.0
Condit. Reinf. inactive responses	0.0	0.1	0.1	0.3	-0.2	-0.1	0.4
Incentive salience index mean	0.5	0.6	1.3	-0.2	-0.1	1.1	1.0
Condit. Reinf. lever presses	1.0	1.4	3.9	-1.2	0.4	2.0	0.3
Time in familiar zone, hab. session 1	0.4	0.3	0.7	0.8	-0.2	-0.6	0.5
Time in novel zone, hab. session 1	0.2	0.2	0.4	-0.6	0.0	0.6	-0.2
Total zone transitions, hab. session 1	0.9	1.2	2.7	0.4	1.7	-0.4	-1.4
Total locomotion distance, hab. session 1	0.1	0.1	0.4	0.2	0.6	0.1	-0.2
Locomotion velocity, hab. session 1	0.1	0.1	0.3	0.3	0.6	-0.1	-0.2
Time in familiar zone, hab. session 2	0.2	0.2	0.3	-0.6	0.1	0.6	-0.1
Time in novel zone, hab. session 2	0.7	0.7	1.0	1.0	-0.7	-0.7	1.0
Total zone transitions, hab. session 2	0.8	1.1	2.5	-0.3	1.6	0.4	-1.2
Total locomotion distance, hab. session 2	0.1	0.1	0.5	0.1	0.7	0.2	-0.3
Locomotion velocity, hab. session 2	0.1	0.2	0.4	-0.0	0.7	0.1	-0.4
Novel to familiar place preference ratio	0.3	0.3	0.5	0.7	-0.2	-0.6	0.4
Novelty place preference	0.1	0.1	0.2	0.4	-0.1	-0.2	0.3
Time in novel zone, NPP test	0.0	0.0	0.0	0.2	0.1	0.1	0.2
Total zone transitions, NPP test	0.6	0.9	2.5	0.2	1.6	-0.0	-1.1
Total locomotion distance, NPP test	0.3	0.4	0.9	0.9	-0.1	-0.7	0.4
Locomotion velocity, NPP test	0.7	1.0	1.8	1.3	-0.5	-1.1	0.8
Pavlov. Cond. lever latency	0.6	0.8	2.2	-0.1	0.8	-0.7	-1.5
Pavlov. Cond. magazine entry latency	0.7	0.9	1.7	-0.9	-0.6	1.3	0.9
Pavlov. Cond. change in total contacts	1.5	1.6	3.8	1.0	-1.3	-0.2	2.0
Pavlov. Cond. index score	0.6	0.7	1.6	-0.6	-0.3	1.3	0.9
Pavlov. Cond. latency score	0.7	0.9	2.1	-0.8	-0.2	1.5	0.8
Pavlov. Cond. lever contacts	0.5	0.6	1.6	0.1	-0.5	0.8	1.3
Pavlov. Cond. magazine entry number	0.4	0.6	1.4	0.0	0.7	-0.6	-1.2
Pavlov. Cond. intertrial magazine entries	0.5	0.6	1.0	0.8	1.0	-0.7	-0.7
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.2	-0.5	-0.4	1.1	1.0
Pavlov. Cond. response bias	0.6	0.7	1.6	-0.1	-0.6	0.9	1.3
Bone: apparent density	1.1	1.8	2.9	-1.3	1.4	1.7	-0.9
Bone surface	0.9	1.5	2.5	-0.9	1.6	1.0	-1.3
Bone volume	1.0	1.7	3.0	-0.9	1.7	1.0	-1.5
Bone: connectivity density	1.4	2.3	2.9	-1.4	1.7	1.7	-1.2
Bone: cortical apparent density	1.1	1.5	2.3	1.0	-1.4	-0.8	1.5
Bone: cortical area	0.5	0.7	1.1	0.9	-0.8	-1.0	0.6
Bone: cortical porosity	0.6	0.6	1.3	-1.1	-0.2	1.1	0.1
Bone: cortical porosity	0.4	0.4	0.7	-0.8	-0.4	0.9	0.2
Bone: cortical thickness	1.3	2.1	3.7	1.0	-1.9	-0.8	1.8
Bone: cortical thickness	0.8	0.9	1.8	-0.2	-1.3	0.5	1.3
Bone: cortical tissue density	0.9	1.2	1.9	0.9	-1.2	-0.6	1.4
Bone: elastic displacement	0.9	1.0	1.3	1.1	-0.9	-0.9	1.1
Bone: elastic work	1.3	1.7	2.4	1.1	-1.6	-1.0	1.4
Bone: endosteal estimation	0.5	1.1	1.6	0.6	1.2	-1.0	-1.3
Bone: endosteal perimeter	0.6	1.1	1.9	0.5	1.3	-0.8	-1.4
Bone: final force	0.1	0.2	0.5	0.2	0.7	-0.1	-0.4
Bone: final moment	0.1	0.2	0.3	0.4	0.6	-0.3	-0.3
Bone: marrow area	0.5	1.1	1.6	0.6	1.2	-1.0	-1.3
Bone: maximum diameter	0.2	0.4	1.2	0.7	-0.0	-1.1	-0.3
Bone: maximum force	0.1	0.2	0.4	0.3	0.6	-0.3	-0.4
Bone: maximum moment	0.1	0.2	0.3	0.5	0.5	-0.5	-0.3
Bone: minimum diameter	0.5	0.8	2.0	-0.1	1.1	-0.5	-1.4
Bone: periosteal estimation	0.3	0.6	1.2	0.7	0.4	-1.1	-0.6
Bone: periosteal perimeter	0.2	0.3	0.6	0.5	0.3	-0.8	-0.4
Bone: post-yield work	0.6	0.8	1.3	-0.7	1.1	1.0	-0.8
Bone: stiffness	2.1	3.3	4.8	-1.5	2.2	1.5	-2.0
Bone: tissue strength	0.6	0.6	1.1	1.1	-0.4	-0.8	0.7
Bone: trabecular number	0.6	1.0	2.1	-1.0	0.8	1.5	-0.4
Bone: trabecular spacing	0.3	0.4	0.9	0.6	-0.5	-1.0	0.1
Bone: trabecular thickness	0.3	0.3	0.4	-0.5	0.6	0.6	-0.6
Bone: trabecular tissue density	1.8	2.5	3.8	1.2	-1.9	-1.3	1.7
Breakpoint value in progressive ratio session	0.8	0.9	1.4	-0.7	1.2	1.2	-0.5
Distance traveled before self-admin	0.5	0.5	1.6	0.6	-0.5	-1.2	-0.1
Distance traveled after self-admin	1.3	1.5	3.1	0.1	1.6	-0.6	-1.8
Delta time in closed arm before/after self-admin	0.3	0.3	0.7	-0.4	0.4	-0.3	-0.9
Delta time in open arm before/after self-admin	0.3	0.3	0.7	0.6	0.9	0.2	0.0
Diff in mean of infusions in LGA sessions	0.5	0.5	1.4	-0.5	0.6	1.2	0.0
Extinction: sum of active levers before priming	2.0	2.0	2.9	-1.2	1.7	1.6	-1.1
Active lever presses in extinction session 6	1.5	1.4	2.1	-1.2	1.2	0.8	-1.5
Delta distance traveled before/after self-admin	2.0	2.1	4.8	-0.5	2.2	0.9	-1.6
Delta ambulatory time before/after self-admin	1.2	1.3	3.3	-0.3	1.8	0.8	-1.1
Time in closed arm before self-admin	0.6	0.6	1.9	-0.5	0.6	1.4	0.3
Time in closed arm after self-admin	0.0	0.0	0.1	-0.3	-0.1	0.0	-0.1
Time in open arm before self-admin	1.7	1.9	2.5	1.2	-1.6	-1.5	1.2
Time in open arm after self-admin	1.5	1.6	3.4	1.8	-0.4	-1.4	1.0
Sum of active levers in priming session hrs 5-6	2.0	1.9	3.4	-1.4	1.3	1.9	-0.8
Time to tail flick, vehicle, before self-admin	1.4	1.4	2.1	-1.3	1.0	1.4	-0.9
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.1	0.4	0.2	-0.0	0.1
Time to tail flick, test, before self-admin	0.7	0.7	1.2	-0.4	-0.8	0.9	1.1
Time to tail flick, test, after self-admin	0.2	0.2	0.4	-0.6	-0.2	0.7	0.3
Delta time to tail flick, vehicle, before/after SA	1.2	1.2	2.0	1.4	-0.5	-1.4	0.6
Delta time to tail flick, test, before/after SA	0.3	0.3	0.7	0.0	0.5	-0.6	-0.8
Ambulatory time before self-admin	0.4	0.4	1.0	0.4	-0.6	-1.0	0.1
Ambulatory time after self-admin	1.4	1.6	2.9	-0.7	1.7	0.4	-1.7
Total heroin consumption	2.6	3.1	5.7	-1.7	1.7	2.4	-0.9
Area under the delay curve	0.1	0.1	0.3	0.1	-0.4	-0.5	-0.1
Delay disc. indifference point, 0s delay	0.7	0.8	1.5	-0.4	1.2	0.1	-1.2
Delay disc. indifference point, 16s delay	0.3	0.3	0.6	-0.3	-0.1	-0.7	-0.8
Delay disc. indifference point, 2s delay	0.3	0.3	0.4	0.5	-0.6	-0.4	0.6
Delay disc. indifference point, 24s delay	0.2	0.2	0.6	0.0	-0.8	-0.1	0.6
Delay disc. indifference point, 4s delay	0.1	0.1	0.3	0.5	0.4	-0.2	0.1
Delay disc. indifference point, 8s delay	0.0	0.0	0.0	-0.0	-0.1	-0.2	-0.1
Delay discount exponential model param	0.1	0.1	0.1	0.0	0.4	0.3	-0.0
Delay discount hyperbolic model param	0.1	0.1	0.1	-0.1	0.3	0.4	-0.1
Fecal boli incidents, locomotor time 1	0.1	0.1	0.4	-0.6	-0.5	0.1	-0.2
Change in fecal boli incidents, locomotor task	0.3	0.3	0.8	0.5	-0.6	-0.0	0.9
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.1	-0.2	-0.3	0.2	0.3
Bouts of movement, locomotor time 1	0.2	0.3	0.6	-0.8	-0.2	0.6	-0.1
Total resting periods, locomotor time 1	0.3	0.3	0.5	-0.6	-0.7	0.6	0.4
Rest time, locomotor task time 1	0.4	0.5	0.8	0.5	-0.9	-0.5	0.8
Distance moved, locomotor task time 1	0.2	0.2	0.7	0.2	0.9	0.0	-0.4
Vertical activity count, locomotor time 1	0.3	0.3	1.0	0.1	1.0	0.2	-0.5
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.2	-0.7	0.0	0.4
Bouts of movement, locomotor time 2	0.3	0.3	0.6	-0.0	-0.7	0.3	0.8
Total resting periods, locomotor time 2	0.1	0.1	0.2	-0.3	-0.4	0.4	0.3
Rest time, locomotor task time 2	0.2	0.3	0.8	-0.1	-0.9	-0.2	0.5
Distance moved, locomotor task time 2	0.3	0.4	0.5	0.7	0.7	-0.6	-0.4
Vertical activity count, locomotor time 2	0.1	0.1	0.4	0.1	0.6	-0.1	-0.4
Weight adjusted by age	0.7	0.7	2.4	0.4	1.5	0.3	-0.6
Seeking ratio, delayed vs. immediate footshock	0.6	0.7	1.0	0.7	-1.0	-0.7	1.0
Locomotion in novel chamber	2.8	3.4	5.7	2.3	-1.2	-2.4	1.2
Locomotion in novel chamber post-restriction	0.5	0.6	1.0	0.8	-0.7	-0.5	1.0
Progressive ratio	0.4	0.4	1.1	1.0	0.1	-0.6	0.4
Food seeking constrained by brief footshock	0.1	0.1	0.2	0.1	-0.5	-0.2	0.2
Seeking ratio, punishment vs. effort	0.2	0.3	0.7	-0.9	-0.5	0.4	-0.1
Run reversals in cocaine runway, females	0.1	0.1	0.2	0.4	-0.3	-0.2	0.5
Run reversals in cocaine runway, males	1.0	1.0	2.2	1.5	0.1	-1.3	0.3
Latency to leave start box in cocaine runway	0.1	0.1	0.2	-0.4	-0.1	0.2	-0.1
Latency to leave start box in cocaine runway, F	0.5	0.5	1.2	-1.1	0.3	0.8	-0.5
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	-0.3	0.3	-0.0	-0.6
Cd content in liver	0.7	0.7	1.3	-0.5	1.1	0.4	-1.1
Co content in liver	0.4	0.5	0.8	-0.7	0.6	0.3	-0.9
Cu content in liver	0.6	0.8	1.7	0.0	-1.1	0.3	1.3
Fe content in liver	0.6	0.7	1.3	-0.9	0.7	1.1	-0.4
K content in liver	1.2	1.2	2.1	-1.4	0.6	1.0	-1.1
Mg content in liver	0.0	0.0	0.1	0.2	-0.2	-0.3	0.1
Mn content in liver	0.3	0.3	0.5	-0.7	-0.5	0.6	0.3
Na content in liver	0.2	0.2	0.4	0.3	-0.4	-0.7	0.0
Rb content in liver	0.1	0.2	0.4	0.2	0.6	-0.2	-0.4
Se content in liver	0.9	1.0	1.6	0.8	-1.3	-0.6	1.2
Sr content in liver	1.1	1.0	1.7	-0.6	1.3	0.5	-1.3
Zn content in liver	0.4	0.5	0.9	0.8	-0.5	-0.3	0.9