Hub : Genes

Dmpk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000015085 0.26 0.14 0.0e+00 0.23 0.23 0.24 0.23 1.6e-25 3.2e-25 6.0e-26 2.3e-25
2 Adipose isoform ratio ENSRNOT00000020428 0.11 0.15 5.6e-04 0.02 0.02 0.02 0.01 1.1e-03 3.3e-03 5.7e-03 7.3e-03
3 Adipose isoform ratio ENSRNOT00000105612 0.1 0.14 9.7e-04 0.02 0.02 0.01 0.01 1.8e-03 6.1e-03 8.4e-03 1.1e-02
4 Adipose intron excision ratio chr1:78734515:78735157 0.1 0.07 2.7e-13 0.11 0.11 0.1 0.11 4.6e-12 7.7e-12 1.9e-11 8.0e-12
5 Adipose intron excision ratio chr1:78734530:78735157 0.06 0.05 1.1e-07 0.06 0.06 0.06 0.06 2.5e-07 1.7e-07 2.5e-07 2.9e-07
6 Adipose mRNA stability ENSRNOG00000015085 0.12 0.11 2.7e-07 0.06 0.06 0.07 0.06 1.1e-07 2.0e-07 3.0e-08 1.6e-07
7 BLA intron excision ratio chr1:78734530:78735157 0.06 0.06 2.2e-03 0.02 0.01 0 0.01 2.8e-02 5.7e-02 2.7e-01 1.5e-01
8 Brain gene expression ENSRNOG00000015085 0.1 0.11 8.9e-06 0.04 0.04 0.02 0.03 6.5e-05 2.1e-04 4.1e-03 3.7e-04
9 Brain intron excision ratio chr1:78734515:78735157 0.13 0.09 7.8e-15 0.16 0.17 0.16 0.16 2.3e-14 3.1e-15 5.2e-15 9.3e-15
10 Brain intron excision ratio chr1:78734530:78735157 0.14 0.12 3.5e-10 0.1 0.12 0.1 0.1 1.1e-09 9.1e-11 1.7e-09 1.5e-09
11 Eye intron excision ratio chr1:78739005:78739312 0.87 0.12 1.0e-02 -0 0 -0.02 -0.01 3.9e-01 2.8e-01 6.6e-01 4.4e-01
12 Liver mRNA stability ENSRNOG00000015085 0.03 0.03 3.0e-04 0.02 0.02 0.01 0.02 1.5e-03 1.1e-03 7.1e-03 2.4e-03
13 NAcc intron excision ratio chr1:78734515:78735157 0.05 0.05 4.9e-04 0.04 0.03 0.04 0.05 4.8e-04 1.8e-03 4.3e-04 2.0e-04
14 PL intron excision ratio chr1:78734515:78735157 0.04 0.05 3.7e-03 0.01 0.02 0.01 0.01 4.2e-02 7.1e-03 3.2e-02 2.4e-02
15 PL intron excision ratio chr1:78734530:78735157 0.69 0.18 3.7e-05 0.02 0.07 0.05 0.03 1.2e-02 1.0e-05 6.2e-05 3.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.72.33.4-1.41.8-1.8-1.51.6-1.61.6-1.6-1.51.3-1.81.6-1.5-1.5-0.0
BMI without tail1.32.64.0-1.52.0-2.0-1.41.7-1.61.7-1.7-1.61.4-2.01.7-1.5-1.5-0.1
Body weight0.93.96.1-1.82.3-2.3-1.72.1-1.92.2-2.1-2.01.7-2.52.1-2.0-1.9-0.3
Epididymis fat weight0.61.55.41.1-0.60.61.4-1.20.2-1.01.01.3-1.50.9-1.21.31.3-2.3
Glucose0.20.40.70.6-0.50.50.6-0.70.5-0.50.50.6-0.50.9-0.70.70.60.5
Heart weight2.53.69.1-1.71.3-1.3-2.01.9-0.51.9-1.9-2.02.2-1.51.9-2.3-2.03.0
Left kidney weight6.618.826.4-4.14.0-4.0-4.64.6-2.74.5-4.5-4.64.6-4.74.6-5.1-4.63.0
Right kidney weight5.315.119.9-3.73.8-3.8-4.14.1-2.54.0-4.0-4.14.1-4.14.1-4.5-4.13.0
Tail length0.10.31.3-0.30.6-0.6-0.20.5-0.30.4-0.3-0.40.2-0.80.5-0.5-0.3-1.2
Length with tail0.20.71.4-0.80.8-0.8-0.70.9-0.60.9-0.8-0.90.8-1.21.0-1.0-0.9-0.3
Length without tail0.10.20.4-0.40.4-0.4-0.50.5-0.30.4-0.4-0.50.5-0.60.5-0.6-0.50.0
Liver weight, left9.214.918.3-3.54.1-4.1-3.93.9-2.74.1-4.1-3.94.0-3.83.9-4.3-4.03.3
Liver weight, right2.03.34.9-1.52.0-2.0-1.71.9-1.41.9-1.9-1.81.7-2.01.9-2.2-1.80.1
Parametrial fat weight0.10.20.4-0.50.2-0.2-0.30.4-0.40.5-0.6-0.40.4-0.40.4-0.1-0.40.6
Retroperitoneal fat weight0.00.00.10.2-0.10.10.3-0.2-0.1-0.20.10.2-0.20.2-0.20.30.2-0.1
Intraocular pressure0.10.11.10.2-0.50.50.1-0.20.4-0.00.10.10.00.4-0.20.10.11.0
Extensor digitorum longus weight1.55.97.3-2.42.5-2.5-2.42.5-2.12.6-2.5-2.52.5-2.62.5-2.7-2.51.3
Soleus weight0.10.20.4-0.40.4-0.4-0.40.5-0.30.4-0.4-0.50.4-0.50.5-0.6-0.50.1
Tibialis anterior weight2.99.913.9-3.13.0-3.0-3.33.4-2.33.2-3.2-3.43.3-3.53.4-3.7-3.31.6
Tibia length0.30.71.2-0.70.8-0.8-1.00.9-0.51.0-1.0-0.90.8-1.10.9-0.9-0.90.1
Number of licking bursts3.54.25.0-2.02.2-2.2-2.02.0-1.92.2-2.2-2.02.0-2.02.0-1.7-2.02.1
Food consumed during 24 hour testing period5.36.47.42.5-2.42.42.7-2.71.9-2.62.62.7-2.72.7-2.72.72.7-2.2
Times rat made contact with spout0.00.00.20.2-0.00.00.2-0.20.4-0.10.10.2-0.10.4-0.2-0.00.10.3
Mean time between licks in bursts0.10.10.20.2-0.50.50.3-0.20.3-0.10.10.2-0.20.1-0.20.30.2-0.3
Mean num. licks in bursts3.74.45.12.2-2.22.22.1-2.12.2-2.22.32.1-2.02.3-2.11.62.1-1.8
Std. dev. time between licks in bursts0.10.11.70.10.2-0.20.10.1-0.10.1-0.1-0.0-0.1-0.30.1-0.3-0.0-1.3
Water consumed over 24 hours0.20.20.40.6-0.40.40.6-0.50.4-0.40.40.5-0.50.6-0.50.30.5-0.5
Indifference point 0 sec0.30.62.4-0.60.3-0.3-0.80.7-0.00.5-0.6-0.80.9-0.60.7-0.9-0.81.5
Indifference point AUC3.44.05.0-2.02.2-2.2-2.02.1-2.01.9-1.9-2.01.9-2.22.1-2.0-2.00.9
Indifference point function ln k1.21.72.81.3-1.61.61.3-1.31.5-1.21.21.3-1.11.7-1.41.01.20.4
Indifference point function log k1.21.72.81.3-1.61.61.3-1.31.5-1.21.21.3-1.11.7-1.41.01.20.4
Delay discounting total patch changes 0 sec0.50.82.6-0.80.5-0.5-0.90.9-0.20.7-0.7-0.91.1-0.70.9-1.2-1.01.6
Delay discounting total patch changes 12 sec1.41.92.6-1.41.5-1.5-1.41.5-1.31.4-1.4-1.41.3-1.61.5-1.3-1.40.7
Delay discounting total patch changes 18 sec1.92.63.2-1.51.6-1.6-1.61.6-1.31.7-1.7-1.71.7-1.61.6-1.8-1.71.3
Delay discounting total patch changes 24 sec0.40.51.1-0.60.7-0.7-0.50.7-1.00.7-0.7-0.60.5-0.90.7-0.6-0.6-0.7
Delay discounting total patch changes 6 sec2.03.04.3-1.71.3-1.3-1.91.9-1.01.7-1.7-1.91.9-1.91.9-2.1-1.91.4
Delay discounting time to switch 0 sec3.35.07.42.1-2.42.42.3-2.31.6-2.22.22.3-2.42.2-2.32.72.4-1.6
Delay discounting water rate 0 sec3.75.98.3-2.32.4-2.4-2.42.5-1.92.4-2.4-2.52.5-2.52.5-2.9-2.51.6
Delay discounting water rate 12 sec0.20.20.7-0.40.5-0.5-0.40.5-0.20.5-0.5-0.50.5-0.50.5-0.8-0.5-0.1
Delay discounting water rate 18 sec0.10.10.4-0.30.4-0.4-0.20.4-0.30.3-0.3-0.40.3-0.50.4-0.6-0.4-0.4
Delay discounting water rate 24 sec0.60.81.2-0.70.9-0.9-0.80.8-0.51.0-1.0-0.80.9-0.60.8-1.1-0.91.1
Delay discounting water rate 6 sec0.71.01.8-0.81.4-1.4-0.81.0-1.00.9-0.9-0.90.9-1.01.0-1.2-0.9-0.1
Locomotor activity2.03.24.6-1.71.5-1.5-2.01.8-0.91.8-1.8-1.92.0-1.71.8-2.0-1.92.1
Locomotor testing distance0.71.11.5-1.00.8-0.8-1.21.1-0.50.9-0.9-1.11.2-1.11.1-1.2-1.11.2
Locomotor testing rearing5.07.99.3-2.72.9-2.9-2.92.9-2.32.9-3.0-2.92.8-3.12.9-3.0-2.91.7
Light reinforcement 10.00.00.3-0.10.1-0.1-0.20.20.0-0.10.1-0.20.2-0.20.2-0.5-0.2-0.3
Light reinforcement 20.20.21.9-0.20.4-0.4-0.20.3-0.5-0.10.1-0.20.0-0.60.3-0.3-0.2-1.4
Reaction time number correct4.86.910.3-2.52.3-2.3-2.72.7-1.52.7-2.7-2.72.9-2.42.7-3.0-2.83.2
Reaction time mean minus median0.50.72.50.5-1.11.10.3-0.71.4-0.50.50.5-0.31.1-0.70.50.51.6
Reaction time mean minus median AUC0.30.43.8-0.2-0.30.3-0.40.10.80.2-0.3-0.20.40.40.0-0.3-0.21.9
Reaction time num false alarms4.05.57.4-2.22.5-2.5-2.32.5-2.02.5-2.5-2.42.3-2.72.5-2.5-2.40.7
Reaction time num false alarms AUC3.34.76.5-2.12.2-2.2-2.12.3-1.82.3-2.3-2.32.1-2.62.3-2.3-2.20.6
Reaction time trials correct on left4.86.910.3-2.52.3-2.3-2.72.7-1.52.7-2.7-2.72.9-2.42.7-3.0-2.83.2
Reaction time trials on left4.86.89.8-2.42.3-2.3-2.72.7-1.52.7-2.6-2.72.9-2.42.7-3.0-2.83.1
Reaction time mean1.82.54.31.5-1.91.91.4-1.62.1-1.51.51.6-1.51.8-1.61.51.5-0.5
Reaction time mean AUC1.52.03.61.3-1.81.81.2-1.51.9-1.41.41.4-1.31.6-1.51.31.4-0.4
Median of all reaction times2.22.93.91.6-1.91.91.6-1.72.0-1.71.71.7-1.71.7-1.71.61.7-1.2
Reaction time omissions0.00.10.3-0.0-0.40.4-0.20.10.4-0.00.0-0.10.1-0.30.1-0.2-0.1-0.5
Reaction time false alarm rate0.20.20.9-0.40.5-0.5-0.30.4-0.50.4-0.5-0.40.2-0.70.4-0.3-0.3-0.9
Reaction time premature initiation rate0.50.71.40.9-0.70.70.8-0.80.7-1.01.00.8-0.90.7-0.80.70.8-1.2
Reaction time premature initiations0.20.30.6-0.40.4-0.4-0.50.5-0.10.3-0.4-0.60.6-0.40.5-0.8-0.60.7
Std. dev. reaction times0.70.92.40.7-1.31.30.5-0.91.5-0.80.80.8-0.51.2-0.90.70.71.0
Reaction time trials completed4.86.89.8-2.42.3-2.3-2.72.7-1.52.7-2.6-2.72.9-2.42.7-3.0-2.83.1
Reaction time trials AUC5.78.210.8-2.72.5-2.5-3.02.9-1.72.9-2.9-3.03.1-2.72.9-3.3-3.13.3
Social response proportion0.70.71.6-0.70.6-0.6-1.00.9-0.10.8-0.8-0.91.0-0.80.9-1.3-1.00.8
Social responses0.50.61.1-0.80.4-0.4-0.90.9-0.30.7-0.7-0.90.9-0.90.9-1.1-0.90.7
Social time4.05.36.62.1-2.62.62.3-2.21.9-2.52.52.3-2.32.1-2.22.42.3-2.2
Conditioned locomotion0.00.00.10.20.2-0.20.2-0.2-0.1-0.10.10.2-0.20.3-0.20.20.2-0.2
Cocaine response after cond. corrected0.50.51.0-0.70.5-0.5-0.90.8-0.30.7-0.7-0.80.8-0.70.8-0.8-0.81.0
Cocaine response after cond. not corrected1.31.41.9-1.21.0-1.0-1.31.3-0.61.2-1.2-1.31.3-1.31.3-1.4-1.31.0
Cocaine response before conditioning1.62.02.6-1.31.6-1.6-1.41.5-1.21.5-1.5-1.41.3-1.61.5-1.5-1.40.4
Saline control response1.62.12.7-1.31.6-1.6-1.51.5-1.11.5-1.4-1.51.5-1.41.5-1.6-1.51.2
Condit. Reinf. active minus inactive responses0.10.10.2-0.10.4-0.4-0.30.2-0.20.4-0.3-0.20.2-0.10.2-0.4-0.20.2
Condit. Reinf. active-inactive response ratio0.40.40.8-0.50.8-0.8-0.70.6-0.40.7-0.7-0.60.7-0.40.6-0.9-0.70.7
Condit. Reinf. active responses0.10.10.10.4-0.20.20.3-0.30.2-0.20.20.3-0.30.3-0.30.30.3-0.3
Condit. Reinf. inactive responses0.70.81.10.9-0.90.91.0-0.90.7-0.80.81.0-1.00.9-0.91.11.0-0.8
Condit. Reinf. lever presses0.20.30.5-0.40.5-0.5-0.60.5-0.10.6-0.6-0.50.6-0.50.5-0.7-0.50.4
Condit. Reinf. lever reinforcers received0.10.10.20.4-0.20.20.3-0.40.2-0.20.30.4-0.40.4-0.40.40.4-0.3
Pavlov. Cond. lever latency0.00.00.00.1-0.00.00.1-0.00.0-0.10.10.00.00.1-0.0-0.10.0-0.0
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.10.1-0.0-0.00.3-0.00.00.0-0.00.00.0-0.2-0.0-0.3
Pavlov. Cond. change in total contacts0.20.30.50.5-0.60.60.5-0.60.7-0.60.60.6-0.50.7-0.60.60.6-0.0
Pavlov. Cond. index score0.00.10.20.2-0.30.30.2-0.20.4-0.20.20.2-0.20.2-0.20.20.2-0.3
Pavlov. Cond. latency score0.10.10.20.3-0.40.40.3-0.30.5-0.30.40.3-0.30.3-0.30.30.3-0.4
Pavlov. Cond. lever contacts0.10.20.2-0.40.3-0.3-0.50.4-0.20.5-0.5-0.40.4-0.40.4-0.4-0.40.2
Pavlov. Cond. magazine entry number0.60.70.9-0.81.0-1.0-0.80.8-0.80.8-0.8-0.80.8-0.90.8-0.8-0.80.6
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.20.4-0.4-0.10.2-0.40.2-0.2-0.20.2-0.10.2-0.1-0.20.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.1-0.20.2-0.0-0.00.4-0.00.10.1-0.00.1-0.0-0.00.0-0.1
Pavlov. Cond. response bias0.00.00.0-0.0-0.00.0-0.10.00.10.2-0.1-0.10.1-0.00.0-0.1-0.10.2
Conditioned reinforcement - actives1.11.12.1-1.01.4-1.4-0.91.0-1.31.0-1.0-0.90.9-1.11.0-0.8-0.9-0.2
Conditioned reinforcement - inactives1.01.12.3-1.01.3-1.3-0.91.1-1.40.8-0.9-1.00.8-1.51.1-0.6-0.9-1.0
Conditioned locomotion2.93.54.8-1.72.2-2.2-1.81.8-1.71.9-1.9-1.91.9-1.71.8-1.9-1.91.5
Intermittent access intake day 1-15 change0.20.20.8-0.40.6-0.6-0.50.5-0.10.5-0.4-0.50.5-0.50.5-0.9-0.50.3
Intermittent access intake escalation0.30.21.0-0.30.5-0.5-0.50.40.10.5-0.4-0.50.5-0.40.4-1.0-0.50.6
Intermittent access intake escalation 20.50.52.9-0.20.3-0.3-0.60.40.60.4-0.4-0.50.7-0.20.4-1.3-0.61.7
Intermitt. access day 1 inactive lever presses0.30.30.9-0.80.5-0.5-0.50.5-0.90.3-0.4-0.50.4-0.60.50.5-0.5-0.1
Intermitt. access day 15 inactive lever presses0.70.82.8-0.91.2-1.2-0.60.8-1.70.6-0.6-0.70.5-1.00.80.2-0.7-0.7
Intermitt. access escalation Index0.20.20.40.4-0.40.40.5-0.40.2-0.20.20.4-0.50.3-0.40.40.4-0.7
Intermittent access day 1 total infusions1.21.32.7-1.21.3-1.3-1.01.2-1.71.2-1.2-1.10.9-1.41.2-0.5-1.1-0.4
Intermittent access day 15 total infusions0.80.91.8-0.91.3-1.3-0.80.9-1.11.1-1.0-0.90.8-1.00.9-0.9-0.9-0.1
Intermittent access terminal intake (last 3 days)1.11.21.8-1.11.3-1.3-1.11.1-1.21.3-1.2-1.11.0-1.11.1-0.8-1.10.5
Intermittent access total infusions2.22.43.5-1.61.7-1.7-1.51.5-1.81.9-1.8-1.51.5-1.61.5-1.0-1.50.6
Intermittent access day 1 locomotion0.20.20.4-0.50.6-0.6-0.50.5-0.70.5-0.5-0.50.4-0.50.5-0.2-0.50.0
Intermittent access day 15 total locomotion0.50.51.1-0.60.8-0.8-0.70.6-0.30.6-0.6-0.70.7-0.50.6-0.9-0.71.0
Intermittent access total locomotion1.72.02.2-1.41.5-1.5-1.51.4-1.31.4-1.4-1.41.5-1.31.4-1.1-1.41.3
Intermittent access standard deviation0.50.51.3-0.70.7-0.7-0.80.7-0.40.8-0.6-0.70.8-0.60.7-0.6-0.71.1
Cocaine induced anxiety1.01.13.20.8-0.80.81.1-1.00.2-1.11.21.1-1.10.9-1.01.81.1-1.1
Post-drug Anxiety0.20.21.20.1-0.60.60.3-0.3-0.3-0.40.50.3-0.30.2-0.31.10.3-0.4
Baseline Anxiety0.60.64.0-0.60.0-0.0-0.80.60.00.7-0.7-0.70.9-0.30.6-0.7-0.72.0
Lifetime Intake1.92.13.2-1.51.6-1.6-1.41.4-1.81.8-1.7-1.41.3-1.51.4-0.9-1.40.4
Incentive Sensitization - Responses0.40.31.4-0.50.7-0.7-0.40.5-1.20.7-0.7-0.40.3-0.60.5-0.2-0.4-0.3
Incentive Sensitization - Breakpoint0.30.31.4-0.50.7-0.7-0.30.4-1.20.7-0.7-0.40.3-0.50.4-0.1-0.4-0.3
Progressive ratio test 1 active lever presses1.01.01.5-1.10.9-0.9-1.01.1-1.21.2-1.1-1.00.9-1.21.1-0.6-1.0-0.0
Progressive ratio test 1 breakpoint0.70.71.3-0.90.7-0.7-0.80.9-1.01.0-0.9-0.90.7-1.10.9-0.5-0.8-0.4
Progressive ratio test 1 inactive lever presses0.60.71.5-0.90.9-0.9-0.80.9-1.20.4-0.5-0.80.7-1.20.9-0.3-0.8-0.7
Progressive ratio test 2 active lever presses0.60.62.0-0.81.0-1.0-0.60.7-1.40.9-0.9-0.70.5-0.90.7-0.3-0.6-0.4
Progressive ratio test 2 breakpoint0.50.62.1-0.70.9-0.9-0.50.6-1.40.9-0.8-0.60.4-0.80.6-0.1-0.5-0.6
Progressive ratio test 2 inactive lever presses0.40.53.9-0.30.7-0.7-0.00.2-1.30.2-0.2-0.1-0.2-0.70.30.4-0.0-2.0
Total sessions with >9 infusions3.13.44.5-1.91.9-1.9-1.81.9-2.12.1-2.1-1.91.8-2.01.9-1.3-1.90.9
Short access day 1 total inactive lever presses1.92.13.3-1.51.6-1.6-1.31.5-1.71.7-1.6-1.41.2-1.81.5-1.0-1.3-0.4
Short access day 10 total inactive lever presses0.50.60.80.7-0.80.80.7-0.70.5-0.90.90.8-0.80.6-0.70.80.8-0.7
Short access day 1 total infusions1.11.12.1-1.01.0-1.0-1.01.1-0.91.5-1.4-1.11.0-1.11.1-1.1-1.00.5
Short access day 10 total infusions2.52.84.0-1.81.7-1.7-1.61.7-2.02.0-1.9-1.71.6-1.81.7-0.8-1.70.6
Short access total infusions0.70.81.7-0.90.9-0.9-0.70.9-1.31.2-1.1-0.80.7-1.00.9-0.3-0.8-0.2
Short access day 1 locomotion1.01.11.6-0.91.0-1.0-1.01.1-0.81.3-1.3-1.11.0-1.11.1-1.1-1.10.6
Short access day 10 total locomotion0.10.10.50.3-0.40.40.1-0.10.7-0.10.10.10.00.3-0.1-0.50.10.7
Short access total locomotion0.10.10.4-0.40.3-0.3-0.30.3-0.60.5-0.4-0.30.3-0.40.3-0.1-0.3-0.0
Compulsive drug intake0.20.20.9-0.2-0.60.60.0-0.20.1-0.20.20.10.00.4-0.21.00.00.8
One hour access (0.3 mA shock)0.00.00.10.2-0.10.10.2-0.20.20.0-0.00.2-0.20.1-0.20.10.2-0.4
One hour access (shock baseline)1.51.72.7-1.11.6-1.6-1.21.3-1.11.5-1.5-1.31.2-1.41.3-1.6-1.20.2
Number of responses in last shaping day3.43.55.6-1.61.8-1.8-1.81.8-1.02.4-2.3-1.81.8-1.61.8-2.3-1.81.9
Context. condit. distance diff. score0.20.20.6-0.30.5-0.5-0.30.4-0.10.5-0.5-0.40.4-0.30.4-0.5-0.40.8
Locomotion velocity, session 10.10.10.80.00.2-0.20.0-0.1-0.1-0.00.00.1-0.00.3-0.20.30.10.9
Locomotion distance, session 10.00.00.30.00.1-0.1-0.1-0.00.2-0.10.1-0.00.20.2-0.0-0.3-0.10.6
Locomotion velocity, session 21.41.71.9-1.31.3-1.3-1.31.3-1.11.3-1.3-1.31.3-1.41.3-1.2-1.31.3
Locomotion distance, session 20.20.20.6-0.40.5-0.5-0.50.5-0.20.4-0.4-0.50.5-0.50.5-0.8-0.50.2
Locomotion velocity, session 30.20.30.5-0.50.5-0.5-0.40.6-0.50.5-0.5-0.50.5-0.70.6-0.6-0.5-0.2
Locomotion distance, session 30.91.01.50.9-1.01.01.0-0.90.8-1.01.01.0-1.00.8-0.90.91.0-1.2
Stereotopy head waving bouts, day 31.21.41.7-1.21.2-1.2-1.21.2-1.11.3-1.3-1.21.2-1.21.2-1.0-1.21.3
Stereotopy head waving duration, day 31.01.21.8-1.01.1-1.1-1.11.1-0.81.1-1.1-1.11.1-1.01.1-1.1-1.11.3
Locomotion velocity, session 70.30.30.50.6-0.50.50.6-0.50.7-0.60.60.5-0.50.6-0.50.30.5-0.7
Locomotion distance, session 70.00.00.20.0-0.10.10.10.00.2-0.10.1-0.0-0.0-0.10.0-0.2-0.0-0.4
Stereotopy head waving bouts, day 70.91.11.6-0.91.2-1.2-1.10.9-1.01.1-1.1-1.01.0-0.80.9-0.9-1.01.3
Stereotopy head waving duration, day 71.01.21.9-1.01.4-1.4-1.11.0-1.21.2-1.2-1.01.0-1.01.0-0.9-1.01.0
Locomotion velocity, session 80.00.00.2-0.00.0-0.00.0-0.00.00.0-0.0-0.00.00.1-0.00.10.00.5
Locomotion distance, session 80.00.00.10.10.2-0.20.10.10.20.1-0.1-0.10.1-0.00.1-0.4-0.1-0.1
Degree of sensitization distance0.50.50.6-0.60.6-0.6-0.70.7-0.30.7-0.7-0.70.7-0.60.7-0.8-0.70.8
Degree of sensitization stereotypy1.31.42.2-1.11.5-1.5-1.21.1-1.31.3-1.3-1.11.1-1.01.1-1.0-1.11.1
Condit. Reinf. active minus inactive responses0.30.30.7-0.50.4-0.4-0.60.6-0.20.4-0.4-0.60.5-0.80.7-0.7-0.6-0.2
Condit. Reinf. active-inactive response ratio0.20.20.5-0.30.4-0.4-0.40.5-0.20.4-0.4-0.50.4-0.70.5-0.7-0.5-0.5
Condit. Reinf. active responses0.10.20.4-0.30.2-0.2-0.40.50.00.2-0.2-0.40.4-0.60.5-0.7-0.4-0.4
Condit. Reinf. inactive responses0.10.10.40.3-0.40.40.3-0.20.6-0.40.40.2-0.20.3-0.2-0.10.2-0.4
Incentive salience index mean0.20.20.6-0.40.2-0.2-0.50.5-0.10.3-0.3-0.50.4-0.80.5-0.6-0.5-0.5
Condit. Reinf. lever presses0.00.10.6-0.0-0.10.1-0.00.1-0.0-0.00.0-0.0-0.1-0.30.1-0.0-0.0-0.8
Time in familiar zone, hab. session 10.20.20.5-0.40.4-0.4-0.40.4-0.30.5-0.5-0.40.5-0.40.4-0.4-0.40.7
Time in novel zone, hab. session 10.50.50.7-0.70.8-0.8-0.80.8-0.60.6-0.6-0.70.7-0.80.8-0.7-0.70.3
Total zone transitions, hab. session 10.10.20.4-0.30.5-0.5-0.40.4-0.20.5-0.5-0.40.4-0.30.4-0.7-0.40.4
Total locomotion distance, hab. session 10.40.50.80.7-0.70.70.9-0.80.3-0.70.70.8-0.80.8-0.80.80.8-0.5
Locomotion velocity, hab. session 11.11.62.11.2-1.21.21.4-1.30.7-1.31.31.3-1.31.3-1.31.41.3-1.0
Time in familiar zone, hab. session 20.40.40.6-0.60.7-0.7-0.60.6-0.80.7-0.7-0.60.6-0.60.6-0.4-0.60.7
Time in novel zone, hab. session 20.10.10.30.3-0.30.30.2-0.30.6-0.30.30.3-0.20.5-0.30.10.30.3
Total zone transitions, hab. session 20.50.71.6-0.80.8-0.8-0.90.8-0.60.8-0.8-0.80.9-0.70.8-0.8-0.81.3
Total locomotion distance, hab. session 20.40.61.00.7-0.60.60.8-0.80.3-0.80.80.8-0.80.9-0.91.00.8-0.3
Locomotion velocity, hab. session 20.30.40.60.6-0.50.50.8-0.70.1-0.60.60.7-0.70.7-0.70.80.7-0.4
Novel to familiar place preference ratio0.50.51.6-0.50.8-0.8-0.70.8-0.30.7-0.7-0.70.7-0.80.8-1.3-0.8-0.5
Novelty place preference0.50.51.4-0.50.8-0.8-0.60.7-0.30.6-0.6-0.70.7-0.70.7-1.2-0.7-0.4
Time in novel zone, NPP test0.60.61.6-0.60.9-0.9-0.70.8-0.30.7-0.7-0.80.8-0.80.8-1.3-0.8-0.1
Total zone transitions, NPP test0.20.31.3-0.40.4-0.4-0.50.4-0.20.5-0.5-0.50.5-0.30.4-0.5-0.51.1
Total locomotion distance, NPP test0.10.21.2-0.30.4-0.4-0.30.3-0.20.4-0.4-0.30.4-0.10.3-0.4-0.41.1
Locomotion velocity, NPP test0.10.10.6-0.20.4-0.4-0.30.2-0.10.3-0.3-0.30.3-0.10.2-0.4-0.30.8
Pavlov. Cond. lever latency0.30.40.40.6-0.50.50.7-0.60.4-0.60.60.6-0.60.6-0.60.60.6-0.4
Pavlov. Cond. magazine entry latency0.10.10.1-0.20.2-0.2-0.30.3-0.30.3-0.3-0.30.3-0.40.3-0.3-0.3-0.0
Pavlov. Cond. change in total contacts0.80.81.30.9-1.01.00.8-0.90.7-0.90.90.9-0.90.8-0.90.90.9-1.1
Pavlov. Cond. index score0.20.20.3-0.50.4-0.4-0.60.5-0.40.5-0.5-0.50.5-0.50.5-0.5-0.50.3
Pavlov. Cond. latency score0.00.00.1-0.20.1-0.1-0.30.2-0.20.3-0.3-0.20.2-0.20.2-0.1-0.20.1
Pavlov. Cond. lever contacts0.40.50.7-0.70.7-0.7-0.70.8-0.60.8-0.8-0.80.7-0.80.8-0.8-0.70.3
Pavlov. Cond. magazine entry number0.00.00.10.0-0.10.10.0-0.10.3-0.10.10.1-0.00.2-0.1-0.00.10.2
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.2-0.2-0.20.20.00.0-0.0-0.20.2-0.10.2-0.3-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.60.5-0.5-0.70.6-0.40.6-0.6-0.60.6-0.70.6-0.6-0.60.5
Pavlov. Cond. response bias1.01.21.7-1.01.1-1.1-1.11.2-0.91.2-1.2-1.21.1-1.31.2-1.3-1.20.5
Bone: apparent density0.10.21.30.4-0.30.30.5-0.30.3-0.20.20.3-0.40.1-0.3-0.00.3-1.1
Bone surface0.10.10.7-0.20.3-0.3-0.20.3-0.10.3-0.3-0.30.2-0.50.4-0.6-0.3-0.8
Bone volume0.00.10.5-0.10.1-0.1-0.00.2-0.00.2-0.2-0.20.1-0.30.2-0.5-0.2-0.7
Bone: connectivity density0.20.32.40.5-0.50.50.6-0.40.5-0.50.50.4-0.50.2-0.40.10.4-1.5
Bone: cortical apparent density0.00.00.60.2-0.00.00.2-0.0-0.0-0.10.10.1-0.2-0.1-0.0-0.00.1-0.8
Bone: cortical area1.11.62.3-1.21.3-1.3-1.31.4-0.81.3-1.3-1.31.3-1.51.4-1.5-1.30.6
Bone: cortical porosity0.10.10.30.1-0.30.30.2-0.30.0-0.20.10.2-0.20.3-0.30.50.30.4
Bone: cortical porosity0.00.00.3-0.2-0.10.1-0.10.1-0.10.1-0.1-0.10.1-0.10.10.1-0.10.5
Bone: cortical thickness0.30.40.8-0.60.6-0.6-0.70.7-0.30.7-0.7-0.70.7-0.80.7-0.9-0.70.3
Bone: cortical thickness1.11.32.1-1.01.1-1.1-1.11.2-0.61.2-1.2-1.21.2-1.11.2-1.4-1.21.1
Bone: cortical tissue density0.10.10.70.3-0.10.10.3-0.10.1-0.20.10.2-0.2-0.0-0.10.10.2-0.8
Bone: elastic displacement1.11.21.91.0-1.01.01.3-1.20.4-1.11.11.2-1.21.1-1.21.41.2-1.0
Bone: elastic work0.00.00.1-0.10.2-0.2-0.00.1-0.20.1-0.1-0.10.0-0.20.1-0.2-0.1-0.4
Bone: endosteal estimation0.00.10.70.2-0.10.10.3-0.20.1-0.20.20.2-0.30.1-0.20.20.2-0.9
Bone: endosteal perimeter0.00.00.2-0.00.2-0.2-0.10.10.00.2-0.2-0.0-0.0-0.20.1-0.1-0.0-0.4
Bone: final force0.30.50.8-0.60.8-0.8-0.60.7-0.50.8-0.7-0.70.6-0.90.8-0.9-0.7-0.0
Bone: final moment0.50.81.2-0.81.0-1.0-0.81.0-0.71.0-0.9-0.90.8-1.11.0-1.1-0.90.1
Bone: marrow area0.00.10.70.1-0.10.10.2-0.20.0-0.10.20.2-0.30.0-0.10.20.2-0.8
Bone: maximum diameter1.93.44.4-1.81.9-1.9-1.92.0-1.31.9-1.9-1.91.9-2.12.0-2.0-1.91.1
Bone: maximum force0.20.30.6-0.50.6-0.6-0.50.6-0.40.6-0.5-0.60.5-0.70.6-0.8-0.6-0.2
Bone: maximum moment0.30.50.8-0.60.7-0.7-0.60.7-0.50.7-0.7-0.70.6-0.90.8-0.9-0.7-0.1
Bone: minimum diameter0.20.30.5-0.50.5-0.5-0.50.6-0.40.5-0.5-0.60.5-0.70.6-0.7-0.6-0.2
Bone: periosteal estimation0.20.30.6-0.50.6-0.6-0.50.6-0.40.6-0.6-0.60.5-0.80.6-0.7-0.6-0.3
Bone: periosteal perimeter0.20.30.5-0.50.6-0.6-0.50.6-0.30.6-0.6-0.50.4-0.70.6-0.6-0.5-0.2
Bone: post-yield work0.60.82.90.8-0.80.80.8-0.70.7-0.90.90.8-0.90.5-0.70.60.8-1.7
Bone: stiffness0.71.21.6-1.11.1-1.1-1.11.2-0.71.1-1.1-1.11.1-1.31.2-1.3-1.10.4
Bone: tissue strength0.40.40.50.6-0.60.60.6-0.70.4-0.60.60.7-0.70.6-0.70.70.7-0.7
Bone: trabecular number0.30.41.60.7-0.60.60.8-0.60.5-0.60.60.6-0.70.5-0.60.30.6-1.3
Bone: trabecular spacing0.30.31.9-0.60.2-0.2-0.60.5-0.30.4-0.4-0.60.6-0.40.5-0.3-0.61.4
Bone: trabecular thickness0.91.01.9-0.91.1-1.1-1.01.1-0.71.0-1.0-1.11.0-1.21.1-1.4-1.10.2
Bone: trabecular tissue density0.71.01.2-0.91.1-1.1-1.01.0-0.71.0-1.0-1.01.0-1.01.0-1.0-1.00.9
Breakpoint value in progressive ratio session4.85.47.22.2-2.32.32.5-2.51.8-2.32.32.5-2.42.6-2.52.72.5-1.2
Distance traveled before self-admin0.20.20.4-0.40.2-0.2-0.50.4-0.00.1-0.2-0.50.5-0.40.4-0.6-0.50.6
Distance traveled after self-admin0.70.81.40.8-1.21.20.8-0.90.7-1.11.00.8-0.80.9-0.90.90.8-0.4
Delta time in closed arm before/after self-admin0.10.10.30.1-0.30.30.1-0.10.5-0.10.10.10.00.2-0.1-0.10.00.5
Delta time in open arm before/after self-admin0.40.33.60.2-0.00.00.4-0.2-0.5-0.20.30.3-0.5-0.1-0.20.40.4-1.9
Diff in mean of infusions in LGA sessions3.13.55.01.8-1.51.52.1-2.01.0-1.91.92.1-2.12.0-2.02.22.1-1.4
Extinction: sum of active levers before priming1.51.52.41.1-1.21.21.4-1.30.8-1.01.01.3-1.41.2-1.31.51.3-1.0
Active lever presses in extinction session 60.10.10.1-0.20.2-0.2-0.10.2-0.40.3-0.3-0.20.1-0.40.2-0.1-0.1-0.4
Delta distance traveled before/after self-admin2.93.17.31.6-1.51.51.9-1.70.7-1.71.71.8-2.01.4-1.72.01.8-2.7
Delta ambulatory time before/after self-admin1.01.11.51.0-1.01.01.1-1.00.6-1.11.11.1-1.10.9-1.01.21.1-1.2
Time in closed arm before self-admin1.31.52.0-1.11.4-1.4-1.31.2-0.91.2-1.2-1.21.3-1.11.2-1.4-1.30.9
Time in closed arm after self-admin0.10.10.50.10.0-0.0-0.0-0.10.3-0.10.10.00.10.3-0.1-0.1-0.00.7
Time in open arm before self-admin0.70.81.10.8-1.01.00.9-0.80.8-0.90.90.8-0.80.8-0.91.00.9-0.4
Time in open arm after self-admin0.70.84.30.6-0.50.50.9-0.7-0.1-0.70.70.8-1.00.3-0.71.00.9-2.1
Sum of active levers in priming session hrs 5-61.51.52.71.0-1.61.61.1-1.21.3-0.90.91.2-1.01.5-1.21.31.10.6
Time to tail flick, vehicle, before self-admin2.93.03.5-1.71.3-1.3-1.91.9-1.21.8-1.9-1.91.9-1.91.9-1.9-1.91.5
Time to tail flick, vehicle, after self-admin0.40.44.3-0.3-0.20.2-0.60.30.50.3-0.3-0.40.70.00.3-0.5-0.52.1
Time to tail flick, test, before self-admin0.30.30.70.4-0.90.90.6-0.50.5-0.00.00.5-0.40.7-0.60.70.50.5
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.00.0-0.30.3-0.30.2-0.2-0.30.3-0.40.3-0.3-0.3-0.1
Delta time to tail flick, vehicle, before/after SA0.30.31.90.3-0.60.60.2-0.41.0-0.30.40.3-0.10.7-0.40.20.21.4
Delta time to tail flick, test, before/after SA1.71.52.3-1.21.2-1.2-1.41.3-1.00.9-0.9-1.31.3-1.41.4-1.5-1.30.7
Ambulatory time before self-admin0.00.00.1-0.1-0.20.2-0.10.10.0-0.00.0-0.10.1-0.00.1-0.1-0.10.2
Ambulatory time after self-admin1.11.21.91.0-1.41.41.0-1.10.9-1.21.21.1-1.01.2-1.11.11.0-0.1
Total heroin consumption0.50.61.40.6-0.90.90.8-0.70.4-0.70.60.7-0.80.5-0.70.90.8-1.2
Area under the delay curve1.51.62.81.2-1.01.01.4-1.30.6-1.31.21.4-1.51.2-1.31.51.4-1.7
Delay disc. indifference point, 0s delay0.90.92.60.8-0.70.71.1-0.90.3-0.90.91.0-1.10.7-0.91.21.0-1.6
Delay disc. indifference point, 16s delay1.01.03.20.9-0.80.81.1-1.00.5-0.90.91.0-1.20.7-1.01.01.1-1.8
Delay disc. indifference point, 2s delay2.83.15.21.5-1.41.41.8-1.80.6-1.81.81.9-2.01.6-1.82.31.9-2.2
Delay disc. indifference point, 24s delay0.00.00.1-0.1-0.00.0-0.20.20.30.2-0.2-0.20.2-0.10.2-0.4-0.20.3
Delay disc. indifference point, 4s delay0.10.10.2-0.10.5-0.5-0.10.1-0.40.2-0.2-0.10.0-0.10.1-0.0-0.1-0.2
Delay disc. indifference point, 8s delay1.51.52.21.1-1.11.11.3-1.30.8-1.21.11.4-1.41.3-1.31.51.3-1.0
Delay discount exponential model param1.11.21.9-1.00.8-0.8-1.21.1-0.51.1-1.0-1.21.2-1.01.1-1.3-1.21.4
Delay discount hyperbolic model param0.90.91.8-0.90.6-0.6-1.01.0-0.30.9-0.9-1.01.1-0.91.0-1.2-1.11.3
Fecal boli incidents, locomotor time 10.00.00.1-0.10.1-0.1-0.00.1-0.20.0-0.0-0.1-0.0-0.20.10.0-0.0-0.4
Change in fecal boli incidents, locomotor task0.80.71.10.8-0.90.90.9-0.90.6-0.80.80.9-0.90.8-0.91.10.9-0.9
Time >=10cm from walls, locomotor time 10.10.10.40.3-0.10.10.3-0.20.2-0.30.20.2-0.30.2-0.20.10.2-0.6
Bouts of movement, locomotor time 12.32.62.91.6-1.51.51.7-1.71.2-1.71.61.7-1.71.7-1.71.71.7-1.3
Total resting periods, locomotor time 12.73.03.51.7-1.61.61.9-1.81.3-1.81.81.8-1.81.8-1.81.91.8-1.5
Rest time, locomotor task time 10.10.10.30.2-0.10.10.3-0.20.2-0.30.20.2-0.30.2-0.20.20.2-0.5
Distance moved, locomotor task time 10.20.20.4-0.50.4-0.4-0.50.4-0.40.5-0.5-0.50.5-0.40.4-0.4-0.40.6
Vertical activity count, locomotor time 10.10.10.60.1-0.10.10.3-0.2-0.2-0.10.10.2-0.4-0.0-0.20.40.3-0.8
Time >=10cm from walls, locomotor time 20.10.10.20.3-0.20.20.4-0.30.1-0.40.40.3-0.40.3-0.30.50.4-0.2
Bouts of movement, locomotor time 25.76.28.22.4-2.62.62.5-2.62.2-2.62.52.6-2.42.9-2.62.62.5-1.2
Total resting periods, locomotor time 25.25.57.72.3-2.52.52.4-2.52.1-2.42.42.4-2.32.8-2.52.42.4-0.9
Rest time, locomotor task time 20.00.00.20.3-0.10.10.3-0.20.3-0.20.10.2-0.20.4-0.20.10.20.1
Distance moved, locomotor task time 20.50.60.8-0.80.7-0.7-0.90.8-0.70.8-0.7-0.80.8-0.90.8-0.7-0.80.6
Vertical activity count, locomotor time 20.20.21.20.2-0.20.20.3-0.3-0.1-0.30.30.3-0.5-0.0-0.30.50.4-1.1
Weight adjusted by age0.00.00.20.00.4-0.40.1-0.1-0.3-0.10.10.1-0.10.0-0.10.10.1-0.4
Seeking ratio, delayed vs. immediate footshock1.51.72.01.3-1.31.31.4-1.41.1-1.31.31.4-1.31.4-1.41.31.3-0.9
Locomotion in novel chamber0.70.92.10.7-1.41.40.6-0.91.1-0.80.80.8-0.61.2-0.90.90.71.0
Locomotion in novel chamber post-restriction1.41.62.21.2-1.51.51.3-1.31.1-1.31.31.3-1.21.3-1.31.41.3-0.5
Progressive ratio0.40.40.80.7-0.60.60.9-0.70.3-0.50.50.7-0.70.8-0.80.90.70.0
Food seeking constrained by brief footshock5.36.57.62.4-2.62.62.5-2.71.8-2.72.72.7-2.62.7-2.72.82.7-2.0
Seeking ratio, punishment vs. effort1.11.42.21.1-1.21.21.0-1.21.0-1.41.41.2-1.21.1-1.11.11.2-1.5
Run reversals in cocaine runway, females0.30.30.90.5-0.30.30.6-0.60.2-0.70.70.6-0.60.5-0.60.60.6-0.9
Run reversals in cocaine runway, males0.70.71.0-0.80.9-0.9-0.90.9-0.50.9-0.9-0.90.9-0.80.9-1.0-0.90.7
Latency to leave start box in cocaine runway0.10.10.50.1-0.40.40.1-0.00.7-0.20.2-0.00.10.1-0.0-0.2-0.00.3
Latency to leave start box in cocaine runway, F0.30.41.6-0.50.1-0.1-0.50.60.30.4-0.4-0.60.8-0.40.6-0.7-0.61.3
Latency to leave start box in cocaine runway, M0.00.00.10.2-0.10.10.1-0.10.3-0.10.10.1-0.10.1-0.1-0.20.0-0.3
Cd content in liver0.10.10.90.1-0.30.30.0-0.20.30.1-0.10.10.00.4-0.20.10.11.0
Co content in liver1.82.23.41.4-1.31.31.6-1.60.8-1.51.51.6-1.61.6-1.61.81.6-0.9
Cu content in liver0.10.10.4-0.50.3-0.3-0.30.3-0.40.3-0.3-0.30.4-0.30.3-0.2-0.30.6
Fe content in liver1.31.53.9-1.11.1-1.1-1.31.2-0.61.3-1.3-1.21.3-0.91.2-1.1-1.22.0
K content in liver0.20.20.6-0.60.5-0.5-0.40.5-0.70.4-0.4-0.50.4-0.70.5-0.3-0.5-0.2
Mg content in liver0.20.20.4-0.40.4-0.4-0.40.5-0.50.3-0.3-0.40.4-0.60.5-0.3-0.4-0.1
Mn content in liver0.91.01.7-1.01.0-1.0-1.01.1-0.90.9-0.9-1.11.0-1.31.1-1.1-1.10.2
Na content in liver0.10.10.50.1-0.40.40.2-0.30.2-0.40.40.2-0.10.3-0.30.40.20.7
Rb content in liver0.00.00.00.1-0.10.10.1-0.10.1-0.10.10.1-0.00.2-0.1-0.10.10.0
Se content in liver1.62.02.4-1.41.4-1.4-1.51.5-1.21.5-1.5-1.51.4-1.51.5-1.3-1.41.2
Sr content in liver0.30.20.3-0.50.5-0.5-0.50.5-0.40.5-0.5-0.50.5-0.60.5-0.4-0.50.5
Zn content in liver0.10.10.4-0.30.5-0.5-0.20.3-0.60.3-0.3-0.30.2-0.30.3-0.3-0.3-0.2